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MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAIAADHRPLAPWAVVLVAAAGAT YLLMYVRRYYGGRIAHLVQHDLRMDAFQALLRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRH VLTLLLGVAVMTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDAAVCGIRVVKA FGQEERETVKLVTASRALYAAQLRVARLNAHFGPLLQTLPALGQMAVFALGGWMAAQGSITVGTFVAFWA CLTLLARPACDLAGMLTIAQQARAGAVRVLELIDSRPTLVDGTKPLSPEARLSLEFQRVSFGYVADRPVL REISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRELTLDSLRSAIGLVPEDAVLF SGTIGANIAYGRPDATPEQIATAARAAHIEEFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPR LLIMDDPTSAVDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVGTPDEVWERCP RYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTNVHNPGPHDHPPGPDPLRRLLREFRGPLALS LLLVAVQTCAGLLPPLLIRHGIDVGIRRHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQVLFRL RSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVAVISVVTLVGILVALLAIRARLVLL IFTTMPVLALATWQFRRASNWTYRRARHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRL GVRGQRLLALYYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYTPIGELAQMFDDYQR AAVAAGRIRSLLSTRTPSSPAARPVGTLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGS GKSTLIKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRDAIAYGRPDATDAQVE RAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQLQLLALARARLVDPDILLLDEATVALDPATEAVVQR ATLTLAARRTTLIVAHGLAIAEHADRIVVLEHGTVVEDGAHTELLAAGGHYSRLWAAHTRLCSPEITQLQ CIDA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0194 | - | - | 100% (1194) | PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER |
| M. tuberculosis H37Rv | Rv1272c | - | 2e-72 | 36.11% (468) | drugs-transport transmembrane ATP-binding protein ABC |
| M. tuberculosis H37Rv | Rv1273c | - | 2e-67 | 31.82% (572) | drugs-transport transmembrane ATP-binding protein ABC |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0200 | - | 0.0 | 99.66% (1194) | drugs-transport transmembrane ATP-binding protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_1748 | - | 1e-106 | 40.81% (566) | ABC transporter related |
| M. leprae Br4923 | MLBr_01113 | - | 4e-70 | 30.89% (505) | putative ABC transporter, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_1414c | - | 1e-71 | 35.41% (466) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_5223 | - | 0.0 | 77.11% (1184) | drug-transport transmembrane ATP-binding protein ABC transporter |
| M. avium 104 | MAV_1421 | - | 1e-76 | 32.80% (561) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_5659 | - | 1e-107 | 39.97% (578) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_3634 | - | 2e-98 | 41.55% (491) | PUTATIVE ABC transporter, ATP-binding protein |
| M. ulcerans Agy99 | MUL_4010 | - | 9e-73 | 32.26% (561) | transmembrane ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_5005 | - | 1e-104 | 41.03% (563) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Rv0194|M.tuberculosis_H37Rv MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAIA
Mb0200|M.bovis_AF2122/97 MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAVA
MMAR_5223|M.marinum_M MRTNWWGRLSRYVLRYRRDLLLGLFASVVGTAITVMVPLVTKRVIDNAIA
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1421|M.avium_104 --------------------------------------------------
MUL_4010|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Rv0194|M.tuberculosis_H37Rv ADHRPLAPWAVVLVAAAGATYLLMYVRRYYGGRIAHLVQHDLRMDAFQAL
Mb0200|M.bovis_AF2122/97 ADHRPLAPWAVVLVAAAGATYLLTYVRRYYGGRIAHLVQHDLRMDAFQAL
MMAR_5223|M.marinum_M PDHRPLAPWALVLVAAAVAIYFMTFVRRHYGGRIAHLVQHDLRVDAFATL
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1421|M.avium_104 --------------------------------------------------
MUL_4010|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Rv0194|M.tuberculosis_H37Rv LRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAV
Mb0200|M.bovis_AF2122/97 LRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAV
MMAR_5223|M.marinum_M MRWDGRQQDRWSSGQLIVRTTNDLELVQTLLFDLPNVIRHLLTLLLCLAV
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1421|M.avium_104 --------------------------------------------------
MUL_4010|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Rv0194|M.tuberculosis_H37Rv MTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDA
Mb0200|M.bovis_AF2122/97 MTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDA
MMAR_5223|M.marinum_M MAWLSLPLALLVVLLVPLIGLVAHRSRRLLAVATEAAQERNAVVTGVVDA
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1421|M.avium_104 --------------------------------------------------
MUL_4010|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Rv0194|M.tuberculosis_H37Rv AVCGIRVVKAFGQEERETVKLVTASRALYAAQLRVARLNAHFGPLLQTLP
Mb0200|M.bovis_AF2122/97 AVCGIRVVKAFGQEERETVKLVMASRALYAAQLRVARLNAHFGPLLQTLP
MMAR_5223|M.marinum_M AVSGIHVVKAFGQQSQETVKLTTAGRALYAARVRVARLNAYFGPLLQSLP
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1421|M.avium_104 --------------------------------------------------
MUL_4010|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Rv0194|M.tuberculosis_H37Rv ALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQ
Mb0200|M.bovis_AF2122/97 ALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQ
MMAR_5223|M.marinum_M AFGQMAVLAVGGWMAAQGTITVGTFVAFWSCLTLVSRPACDLAGMLTIAQ
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1421|M.avium_104 --------------------------------------------------
MUL_4010|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Rv0194|M.tuberculosis_H37Rv QARAGAVRVLELIDSRPTLVDGTKPLSPEARLSLEFQRVSFGYVADRPVL
Mb0200|M.bovis_AF2122/97 QARAGAVRVLELIDSRPTLVDGTKPLSLEARLSLEFQRVSFGYVADRPVL
MMAR_5223|M.marinum_M QARTGAMRVFELIDSRPTLVDGTKQLPSSTPVSLAFEQASFGYAAEHPVL
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1421|M.avium_104 --------------------------------------------------
MUL_4010|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Rv0194|M.tuberculosis_H37Rv REISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRE
Mb0200|M.bovis_AF2122/97 REISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRE
MMAR_5223|M.marinum_M RGIDLSVRPGETLAVVGPPGSGKSTLALLAMRCYDVTAGAVRVGGHDVRD
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1421|M.avium_104 --------------------------------------------------
MUL_4010|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Rv0194|M.tuberculosis_H37Rv LTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE
Mb0200|M.bovis_AF2122/97 LTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE
MMAR_5223|M.marinum_M LTLDSLRSAIGLVPEQAILFSGTIGENISYGRSNVTLEQITAAARAAHID
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1421|M.avium_104 --------------------------------------------------
MUL_4010|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Rv0194|M.tuberculosis_H37Rv EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSA
Mb0200|M.bovis_AF2122/97 EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSA
MMAR_5223|M.marinum_M EFVNTLPDGYATPVGAQGLTLSGGQRQRIALARALVGNPRLLIMDEPTSA
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1421|M.avium_104 --------------------------------------------------
MUL_4010|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01113|M.leprae_Br4923 ---MTMAT-------APATRSCDFYCTIRRLLKQLVPQRRLSLT------
MAB_1414c|M.abscessus_ATCC_199 ---MTRAIGFRGVQQGPAERSRDFRGTAIRMVKRLAPQRFLTAT------
Rv0194|M.tuberculosis_H37Rv VDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVG
Mb0200|M.bovis_AF2122/97 VDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVG
MMAR_5223|M.marinum_M VDAVIEASIQDVLREVLADRTAVIFTRRRSMLSLADRVAVLDSGHLLDIG
MSMEG_5659|M.smegmatis_MC2_155 -------------------------------MSVTDWRGRLQE-------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK -------------------------------MTETNWRGKFDE-------
Mvan_5005|M.vanbaalenii_PYR-1 ------------------------------MSADGEWRGKYDE-------
MAV_1421|M.avium_104 --------------------------------------------------
MUL_4010|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01113|M.leprae_Br4923 -----------------VITLGITGTAIGIIVPWVLGHTT----------
MAB_1414c|M.abscessus_ATCC_199 -----------------VITLSMIGIAIGVIGPRILGHAT----------
Rv0194|M.tuberculosis_H37Rv TPDEVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTN
Mb0200|M.bovis_AF2122/97 TPDEVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTN
MMAR_5223|M.marinum_M TPEQLWGRCSRYRELLSPATDPLRSLAFEDGVPEPESEP-----EAIDVA
MSMEG_5659|M.smegmatis_MC2_155 -----------------EQDPNNDNLPIDESIPLRREAR-----------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK -----------------SAD-----LPIDETVPRQREAR-----------
Mvan_5005|M.vanbaalenii_PYR-1 -----------------HTD-----LPIDETVPRRREAR-----------
MAV_1421|M.avium_104 --------------------------------------------------
MUL_4010|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01113|M.leprae_Br4923 ------------DLLFNGVIGRQLPKGISKTQAVAAARTRGDNALADLLS
MAB_1414c|M.abscessus_ATCC_199 ------------DLLFNGVIGRQLPAGQSREQAVETARARGDGQFAQMLS
Rv0194|M.tuberculosis_H37Rv VHNPGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRH
Mb0200|M.bovis_AF2122/97 VHNPGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRH
MMAR_5223|M.marinum_M ADATGPSDHSPKPDLLRRLLHDFRGPLIVSLLLVALETGAGLLPPLLIRH
MSMEG_5659|M.smegmatis_MC2_155 -------------SLLISLLRPYRWIVAVLALVVIVENAARLSVPVLVQR
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK -------------ALLGSLLRPYRWAVVLLAVVVVVENAARLSVPILVQK
Mvan_5005|M.vanbaalenii_PYR-1 -------------SLLYLLLRPYRWVVLALAVVVVVENAARLSVPLLVQK
MAV_1421|M.avium_104 --------------MLLALLRQYIQPYRRLVAVLMALQVISNLASLYLPT
MUL_4010|M.ulcerans_Agy99 --------------MLLALLRQYIRPYRRLVAALMALQLISTLASLYLPT
MLBr_01113|M.leprae_Br4923 GMNLVPG---QGVDFVAVGRTLGLALSLYLVYTLLTWAQARLLNVTVQRI
MAB_1414c|M.abscessus_ATCC_199 GMNVIPG---QGVDFHAIGMTLALALSLYLIAGMLAWVQARLLNVTVQRT
Rv0194|M.tuberculosis_H37Rv GIDVGIR----RHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQV
Mb0200|M.bovis_AF2122/97 GIDVGIR----RHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQV
MMAR_5223|M.marinum_M GIDVGIR----QHVLTALWWAALAGAAIVAIRLVAQWGSAVVAGTAGEKA
MSMEG_5659|M.smegmatis_MC2_155 GIDHGIPPILAGGPARELMVIVATLCAVVLVQATSRMFFLRRSGRVGQKV
TH_3634|M.thermoresistible__bu ------------------------------------MYFLRRSGRIGQEV
Mflv_1748|M.gilvum_PYR-GCK GIDDGIPPLLEGGPAITLMTIVATLCGVVVVQAVGRMYFLRRSGRIGQKV
Mvan_5005|M.vanbaalenii_PYR-1 GIDDGIPPLLAGERATTLLTIVAALCGVVVVQACSRMYFLRRSGRIGQKV
MAV_1421|M.avium_104 VNAAIIDEGVAKGDTSTIVRLGVVMLGVTAVQALCAVGAVYFGSRTGMGF
MUL_4010|M.ulcerans_Agy99 VNAAIIDDGVAKGDTNTIIRLGVVMLGVTGLQVLCAVGAVYFGARTGTGF
MLBr_01113|M.leprae_Br4923 MFALRSDVEDKVHRLPLSYCDTRQRGELLSRVTNDIDNLQSSLSITLSQL
MAB_1414c|M.abscessus_ATCC_199 VVALRTEVENKIHRLPLSYFDSRQRGEILSRVTNDVDNIQTSLQMSINQL
Rv0194|M.tuberculosis_H37Rv LFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVA
Mb0200|M.bovis_AF2122/97 LFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVA
MMAR_5223|M.marinum_M LFRLRSLVFAHAQRLDLDAFEDNGDSQIITAVTADVDAIVAFLRTGLVIA
MSMEG_5659|M.smegmatis_MC2_155 LLELRRRVFRHFQRLDLAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL
TH_3634|M.thermoresistible__bu LLELRRRLFRHFQRLDVAFHERYTSGRVVSRSTNDVEAIQDMLETGFDSL
Mflv_1748|M.gilvum_PYR-GCK LLELRRRVFRHFGRLDIAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL
Mvan_5005|M.vanbaalenii_PYR-1 LLELRRRVFRHFGRLDIAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL
MAV_1421|M.avium_104 GRDLRAAMFEHVITFSERETARFGAPTLLTRSTNDVRQIQYLVQITATVL
MUL_4010|M.ulcerans_Agy99 GRDLRAAMFEHVITFSERETARFGASTLLTRSTNDVRQIVFLVQTTATVL
** : : : ::: * *: : :
MLBr_01113|M.leprae_Br4923 LTSLLTVVAVLVVMVSVSPLLALVALLTVPMSLLATRAIAQRSQQLFVAQ
MAB_1414c|M.abscessus_ATCC_199 LSSMLTLVAVLAMMLSISPLLAVITLATVPLSLWVTRTIARRSQRLFVAQ
Rv0194|M.tuberculosis_H37Rv VISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRA
Mb0200|M.bovis_AF2122/97 VISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRA
MMAR_5223|M.marinum_M IVSLVTAVGILAALLAINAKLALLIFATLPMLGLATWQFRRASSWTYRQA
MSMEG_5659|M.smegmatis_MC2_155 ITAVLTLFGTAVLLVVLDWRLGLMCLAAFPILVALVWWFRNESARTYRKV
TH_3634|M.thermoresistible__bu ITAVLTLGGTAILLVTLDVRLGLMCLGAFPVLIALVWWFREESAKTYRKV
Mflv_1748|M.gilvum_PYR-GCK ITAVLTMVGTAVLLVVLDVKLGLMCLVAFPVLVLLVWWFQRESSKTYREV
Mvan_5005|M.vanbaalenii_PYR-1 ITAVLTLVGTAVLLVVLDVKLGLMCLAAFPILVLLVMWFRRESSKTYREV
MAV_1421|M.avium_104 VTAPIMCLGGIVMAIHQEAALTWLLLISVPVMALTNYWVMSHMLPLFRRM
MUL_4010|M.ulcerans_Agy99 VAAPIMSIGGIIMAVHQEAALTWLLLVSVPILALANYWIMTHMLPLFRSM
: : : . : * : : :.*: . :
MLBr_01113|M.leprae_Br4923 WTSAGRLNAHIEETYSGLTVVKTFGHQTAAREQFRNVNNDVYQASFSAQF
MAB_1414c|M.abscessus_ATCC_199 WANTGKLNAHIEETYSGFTIVKTYGHRAEAEAIFADRNAEVYRSAFGAQF
Rv0194|M.tuberculosis_H37Rv RHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQR
Mb0200|M.bovis_AF2122/97 RHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQR
MMAR_5223|M.marinum_M RQRLGTVTATLREYSAGLRIAQAYRAEYVGFQTYFAHSDDYRRLRVRGQR
MSMEG_5659|M.smegmatis_MC2_155 RESAALVIVQFVETMTGIKAVQAYRREPRNQEIFSDIADDYREINEKTFK
TH_3634|M.thermoresistible__bu RESAALVIVQFVETMTGIKAVQAYRREPRNQEIFEQVADDYREINEKTLR
Mflv_1748|M.gilvum_PYR-GCK REISALVIVQFVETMTGIKAVQAYRREPRNQQIFEDVADRYREINERTFK
Mvan_5005|M.vanbaalenii_PYR-1 REISALVIVQFVETMTGIKAVQAYRREPRNQQIFEDIADRYRVINEKTFK
MAV_1421|M.avium_104 QALIDGVNRVMRDQLSGVRVVRAFAREDFERDRFDRANATLSNTALAAGN
MUL_4010|M.ulcerans_Agy99 QALIDGINRVLRDQLSGVRVVRAFTREPFERDRFAQANTALASTALRAGN
: : : :*. .::: . :
MLBr_01113|M.leprae_Br4923 FSGLVSPATMFISNLGYVVVAALGGLQVATGHITLGNIQAFIQYVRQFNM
MAB_1414c|M.abscessus_ATCC_199 FSGLVSPATAFVGNLSYVAVAVVGGLKVASGGLTLGSIQAFSQYVRQFNQ
Rv0194|M.tuberculosis_H37Rv LLALYYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYT
Mb0200|M.bovis_AF2122/97 LLALYYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYT
MMAR_5223|M.marinum_M LLALYFPLVPLTCSLATTLVLFEGGRDVQAGVLSVGALVTYLLYVEMLFA
MSMEG_5659|M.smegmatis_MC2_155 LLAIFMPGVKLVGNITTGVVLIYGGYRVLNDQMTIGTLAAFLLYLRMFFE
TH_3634|M.thermoresistible__bu LLAIFMPGVRLVGNITTGVVLLYGGYLVLNDQMTIGTLTAFLLYLRMFFE
Mflv_1748|M.gilvum_PYR-GCK LLAVFMPGVKLVGNLTTGVVLLYGGYRALHGEMTIGTLTAFLLYLRMFFE
Mvan_5005|M.vanbaalenii_PYR-1 LLAVFMPGVKLVGNLTTGVVLLYGGYRVLHGEMTIGTLAAFLLYLRMFFE
MAV_1421|M.avium_104 WQALMLPVTTLTINVSSVALIWFGGLRIDHGQMQVGSLTAFLAYFTQILM
MUL_4010|M.ulcerans_Agy99 WQALMLPVTTLTINVSSVAVIWFGGLLIDQGRMQVGSLSAFLSYFAQILM
.: * . : .: : *. . : :* : :: *. :
MLBr_01113|M.leprae_Br4923 PLSQVAGIYNTLQSGLASAERVFDLLDEPEELPDPMLALPPPHGQVPRIN
MAB_1414c|M.abscessus_ATCC_199 PLTQVAAMYNTLQSGLASAERVFELLDADEETPDPLAAATAPTGSV----
Rv0194|M.tuberculosis_H37Rv PIGELAQMFDDYQRAAVAAGRIRSLLST----RTPSSPAARPVG---TLR
Mb0200|M.bovis_AF2122/97 PIGELAQMFDDYQRAAVAAGRIRSLLST----RTPSSPAARPVG---TLR
MMAR_5223|M.marinum_M PVDKLSQMFDEYQRAAVAVGRIRSLLNT----PTAFSPSAAPVG---TLR
MSMEG_5659|M.smegmatis_MC2_155 PMQEISQFFNTFQSASSALEKLAGVLAQ----RPGIADPERPVA-LHAVA
TH_3634|M.thermoresistible__bu PMQEISQFFNTFQSAASALEKLAGVLAE----EPAIKDPQHPVSPARPVR
Mflv_1748|M.gilvum_PYR-GCK PMQEISQFFNTFQSASSALEKLAGVLAE----KPGISDPAKPVR-VDEVR
Mvan_5005|M.vanbaalenii_PYR-1 PMQEISQFFNTFQSAASALEKLAGVLAE----KPGISDPPHPVA-LGEVR
MAV_1421|M.avium_104 AVLMATMTLVVLPRASVCAERITEVLST----GAAVADPASPKSPPGAIT
MUL_4010|M.ulcerans_Agy99 AVLMATMTLVVLPRAAVCAERITEVLST----PAALNNPQHPRFPAAGIT
.: : . . :: :* *
MLBr_01113|M.leprae_Br4923 GRVEFQQVSFAYRT-GTPVIDDLSMVVEPGSTVAIVGPTGAGKTTLVNLL
MAB_1414c|M.abscessus_ATCC_199 -RVEFEDISFGYSP-GQPVIEGLSLRVEPGQTVAIVGPTGAGKTTLVNLL
Rv0194|M.tuberculosis_H37Rv GEVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGSGKSTLIKLV
Mb0200|M.bovis_AF2122/97 GEVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGSGKSTLIKLV
MMAR_5223|M.marinum_M GEIEFDAVHFRYPTRDAPALAGINLRIPAGQTVVFVGSTGSGKSTLMKLV
MSMEG_5659|M.smegmatis_MC2_155 GTITFDHVHFAYAP-GRPVLPDLTLTVPAGQTVALVGTTGAGKTTIAKLI
TH_3634|M.thermoresistible__bu GEIAFHGVQFAYVP-GRPVIPELTLTVPAGQTVALVGTTGAGKTTIATLI
Mflv_1748|M.gilvum_PYR-GCK GEVALLDVHFAYVP-GRPVLPGLDLVIPAGQTVALVGTTGAGKTTIAKLI
Mvan_5005|M.vanbaalenii_PYR-1 GEIALRDLTFEYVP-GRPVLPGLDLVIPAGQTVALVGTTGAGKTTIAKLI
MAV_1421|M.avium_104 GIVRLDRATFTYPGADRPVLQDISLTARPGTTTAIVGSTGSGKSTLISLI
MUL_4010|M.ulcerans_Agy99 GAVRLENITFSYPGADCPVLQDISLSAPPGATTAIVGSTGSGKSTLISLI
: : : * *.: : : .* *..:**.**:**:*: .*:
MLBr_01113|M.leprae_Br4923 MRFYDVDSGQILIDGVDITTVSRHALRSRIGMVLQDAWLFDGTIAENIAY
MAB_1414c|M.abscessus_ATCC_199 MRFYEVDSGRILLDGIDVSTMTRHDLRSRMGMVLQDTWLFGGTIVENIAY
Rv0194|M.tuberculosis_H37Rv ARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRDAIAY
Mb0200|M.bovis_AF2122/97 ARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRDAIAY
MMAR_5223|M.marinum_M SRFYDPTDGIIRVDGCDLREFDIDGYRSRLSIVAQEPYLFAGTVRDAIAY
MSMEG_5659|M.smegmatis_MC2_155 ARFYDPTSGTVTLDGVDLRDLSQSELRRHVVMVTQENFMFEGTVADNIRF
TH_3634|M.thermoresistible__bu ARFYDPTAGSVTLDGIDLRDIAQSELRRHVVMVTQENFMFDGTVADNIRF
Mflv_1748|M.gilvum_PYR-GCK TRFYDPGSGTVSLDGVDLRDMSQADLRRHVVMVTQENFMFGGTIADNIRF
Mvan_5005|M.vanbaalenii_PYR-1 TRFYDPVAGTVMLDEIDLRDVAQAELRRHVVMVTQENFMFGGTVADNIRF
MAV_1421|M.avium_104 CRLYDVTGGAVQIDGIDVRDYRTERLWSAIGLVPQRGYLFSGTVADNLRY
MUL_4010|M.ulcerans_Agy99 CRLYDVTGGTVLLDGIDVRDYQTERLWAAIGLVPQRGYLFSGTVADNLRY
*:*: * : :* *: : :* * ::* **: : : :
MLBr_01113|M.leprae_Br4923 GRPQASEDEVMEAAKAAYVDRFVHTLSAGYQTRVSGDGDNISAGEKQLIT
MAB_1414c|M.abscessus_ATCC_199 GRPGASQEEILEAARAAYVDRFVRTLPDGYDTKIADDGGNISAGEKQLIT
Rv0194|M.tuberculosis_H37Rv GRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQLQLLA
Mb0200|M.bovis_AF2122/97 GRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQLQLLA
MMAR_5223|M.marinum_M GRPDATDAQVERAAREVGAHPMIAALDGGYQHEVAAGGRNLSAGQLQLLA
MSMEG_5659|M.smegmatis_MC2_155 GRPDATDAQVRAAAEAVGADRFIATLPEGYGTDVAKRGGRLSAGQRQLIA
TH_3634|M.thermoresistible__bu GRPEATDAEIAAAAEAVGADRFIAALPDGYHTDVAKRGSRLSAGQRQLIA
Mflv_1748|M.gilvum_PYR-GCK GRPGATDDEVRAAARAVGAHTFIDVLPDGYDTDVAKRGGRLSAGQRQLVA
Mvan_5005|M.vanbaalenii_PYR-1 GRPDATDDEVRAAARAVGAHTFIGALPDGYDTDVAKRGGRLSAGQRQLVA
MAV_1421|M.avium_104 GRADATEQQMWEALRVAAADDFVGAHPDGLHMRVAQGGINFSGGQRQRLA
MUL_4010|M.ulcerans_Agy99 GKSDATDEEMWEALRVAAAEEFVRAH--GLQMRVAQGGINFSGGQRQRLA
*:. *:: :: * . . .. :: . * :: * .:*.*: * ::
MLBr_01113|M.leprae_Br4923 IARAFLARPQLLILDEATSSIDTRTEALIARATHDLLQDRTSFIIAHHLP
MAB_1414c|M.abscessus_ATCC_199 IARAFLARPQLLILDEATSSVDTRTELRIQRAMAELRRDRTSFIIAHRLS
Rv0194|M.tuberculosis_H37Rv LARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVAHGLA
Mb0200|M.bovis_AF2122/97 LARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVAHGLA
MMAR_5223|M.marinum_M LARARLVDSDILLLDEATVALDPATEALVHWATLGLAADRTTLIIAHELA
MSMEG_5659|M.smegmatis_MC2_155 FARAFLADPAVLILDEATSSLDIPSERMVQRALETVLADRTALVIAHRLS
TH_3634|M.thermoresistible__bu FARAFLADPAVLILDEATSALDIPSERMVQRALRTVLADRTALVIAHRLS
Mflv_1748|M.gilvum_PYR-GCK FARAFLADPAVLILDEATSSLDIPSERLVQRALETVLADRTAVVIAHRLS
Mvan_5005|M.vanbaalenii_PYR-1 FARAFLADPAVLILDEATSSLDIPSERMVQRALETVLADRTAVVIAHRLS
MAV_1421|M.avium_104 IARAVIRRPAIYLFDDSFAALDARTDSRVRAALREITCDATVIVVTQRVS
MUL_4010|M.ulcerans_Agy99 IARAIIGRPAVYLFDDAFSALDVHTDARVRASLRELATKSAIIIVTQRVS
:*** : . : ::*:: ::* :: : : : : .:::: :.
MLBr_01113|M.leprae_Br4923 TIRDADHILVVAAGKIVEQGSHAKLLARRGAYYRMTQA------------
MAB_1414c|M.abscessus_ATCC_199 TIRDADRIVVLDGGRVTESGTHTELLARHGAYFAMTQS------------
Rv0194|M.tuberculosis_H37Rv IAEHADRIVVLEHGTVVEDGAHTELLAAG-GHYSRLWAAHTRLCSPEITQ
Mb0200|M.bovis_AF2122/97 IAEHADRIVVLEHGTVVEDGAHTELLAAG-GHYSRLWAAHTRLCSPEITQ
MMAR_5223|M.marinum_M IAEFVDRIVVLEQGTIVEDGTHVELLAAG-GRYAALWAAHSRVGRPSPSD
MSMEG_5659|M.smegmatis_MC2_155 TVQIADRVLVLEHGRIIEDGSPADLIGRTDGAYAALHRAWVDSLA-----
TH_3634|M.thermoresistible__bu TVEIADRVLVLERGRVVEDGPPGELIRRGEGRYAALHHAWLESLG-----
Mflv_1748|M.gilvum_PYR-GCK TVQIADRVLVLEHGRIVEDGPPEELTAREGGHYAALHRSWVQSLA-----
Mvan_5005|M.vanbaalenii_PYR-1 TVQIADRVLVLEHGRIVEDGAPDELTARDHGHYAALHRSWVQSLA-----
MAV_1421|M.avium_104 IAATADQVVVIDDGKVAGAGTHDALLTDCAVYAEFADSQSVGAVPSGHTG
MUL_4010|M.ulcerans_Agy99 TAAQADQVIVIDDGRVVGAGTHDSLLIDCPTYAEFAVSQSVTADIRGVS-
.*:::*: * : *. *
MLBr_01113|M.leprae_Br4923 ------------------
MAB_1414c|M.abscessus_ATCC_199 ------------------
Rv0194|M.tuberculosis_H37Rv LQCIDA------------
Mb0200|M.bovis_AF2122/97 LQCIDA------------
MMAR_5223|M.marinum_M DRPIPTELLVHSPDTDVL
MSMEG_5659|M.smegmatis_MC2_155 ------------------
TH_3634|M.thermoresistible__bu ------------------
Mflv_1748|M.gilvum_PYR-GCK ------------------
Mvan_5005|M.vanbaalenii_PYR-1 ------------------
MAV_1421|M.avium_104 STP---------------
MUL_4010|M.ulcerans_Agy99 ------------------