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M. smegmatis MC2 155 MSMEG_5660 (-)

annotation: ABC transporter ATP-binding protein
coordinates: 5751434 - 5753386
length: 650

VVTEPPQSHRDGLRSAPAIAPAPERKRAATDLRRLLPYLLPYRARWVTMVVVAIVSLGATIAIPLMTKAV
IDGPVRHQDSQGLWTLGAAAVGIGISEAVLWFIRRWLVARATMGVEADIRKDLYARLQILPMSFHGRWQS
GQLLSRVMNDLSTIRRFMSFGLVFLILNGLQITVVTAILLAMYWPLGVVVLVSIVPIAATVLHFEREYTR
LSRLAQDQTGHVATHVEESALGLRVVKSFGREDYVFDRFDEQATRLYDTQVARVGVSAKFWTLLEVIPNL
TLIVVLGFGAYAAGHGYVTMGTLVAFITMMLSLVWPIASLGFLLSMTQESFTAANRIAEIFDAPREIVDG
PITEAPRGGRLQLRDVGFKFPDSDEWVLRGVNLTVEPGETVALVGSTGSGKSVLAALFSRLYDVTEGQIL
IDGRDIRDLSLPALRRTVATAFEDPTLFSMSVAENLRLGRSDATDDELEQAVEVAAAHFVYDLPFGLDTR
IGEQGMSLSGGQRQRLSLARAILAAPRILVLDDTLSALDVHTEARVTEALSRVLSSVTGVIVAHRASTVL
LADKVALLDRDAHGAGTVTHIGTHAELLAEVPQYRYLLAADDELDDDTERTCEWEDDEDLERLRRVHDER
AAIDGLDEPEYLGQEVQRR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5660--100% (650)ABC transporter ATP-binding protein
M. smegmatis MC2 155MSMEG_5008-9e-8234.09% (569) ABC transporter, ATP-binding protein
M. smegmatis MC2 155MSMEG_5659-2e-7131.34% (568) ABC transporter, ATP-binding protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0200-1e-8233.74% (578) drugs-transport transmembrane ATP-binding protein ABC
M. gilvum PYR-GCKMflv_1747-0.082.31% (616) ABC transporter related
M. tuberculosis H37RvRv0194-3e-8333.45% (577) drugs-transport transmembrane ATP-binding protein ABC
M. leprae Br4923MLBr_01113-2e-7029.27% (632) putative ABC transporter, ATP-binding component
M. abscessus ATCC 19977MAB_1415c-6e-7231.23% (570) ABC transporter ATP-binding protein
M. marinum MMMAR_5223-8e-8334.80% (569) drug-transport transmembrane ATP-binding protein ABC
M. avium 104MAV_1421-7e-7331.11% (569) ABC transporter, ATP-binding protein
M. thermoresistible (build 8)TH_2635-0.079.54% (611) PUTATIVE ABC transporter related
M. ulcerans Agy99MUL_4010-1e-7030.81% (568) transmembrane ATP-binding protein ABC transporter
M. vanbaalenii PYR-1Mvan_5006-0.080.35% (626) ABC transporter-related protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0200|M.bovis_AF2122/97            ---------------------------MRTNCWWRLSGYVMRHRRDLLLG
Rv0194|M.tuberculosis_H37Rv         ---------------------------MRTNCWWRLSGYVMRHRRDLLLG
MMAR_5223|M.marinum_M               ---------------------------MRTNWWGRLSRYVLRYRRDLLLG
Mflv_1747|M.gilvum_PYR-GCK          -----MADSRTDSLHAAPAIGPPPSRVRPSSDLWRMMPYLLPYRGRWIVM
Mvan_5006|M.vanbaalenii_PYR-1       -----MADTGFDSLRAAPSIGPPPKRVKPSSDLWRMMPYLLPYRGRWIVM
MSMEG_5660|M.smegmatis_MC2_155      MVVTEPPQSHRDGLRSAPAIAPAPERKRAATDLRRLLPYLLPYRARWVTM
TH_2635|M.thermoresistible__bu      --------VVTGRLHEAAKIAPPPERSWVGADLWRLLPYLMPYRARWTAM
MAV_1421|M.avium_104                ------------------------------MLLALLRQYIQPYRRLVAVL
MUL_4010|M.ulcerans_Agy99           ------------------------------MLLALLRQYIRPYRRLVAAL
MAB_1415c|M.abscessus_ATCC_199      --------------------------MPQGQLRALLPRYVRPYRGLIAVV
MLBr_01113|M.leprae_Br4923          ---------------MTMATAPATRSCDFYCTIRRLLKQLVPQRRLSLTV
                                                                       :   :   *      

Mb0200|M.bovis_AF2122/97            FGAALAGTVIAVLVPLVT----KRVIDDAVAA-DHRPLAPWAVVLVAAA-
Rv0194|M.tuberculosis_H37Rv         FGAALAGTVIAVLVPLVT----KRVIDDAIAA-DHRPLAPWAVVLVAAA-
MMAR_5223|M.marinum_M               LFASVVGTAITVMVPLVT----KRVIDNAIAP-DHRPLAPWALVLVAAA-
Mflv_1747|M.gilvum_PYR-GCK          IVVALASLAATISIPLMT----KAVIDGPVRQQDQQGLWLVGAAALGVG-
Mvan_5006|M.vanbaalenii_PYR-1       IVVALASLAATISIPLMT----KAVIDGPVRHQDQQGLWLVGAAAVAVG-
MSMEG_5660|M.smegmatis_MC2_155      VVVAIVSLGATIAIPLMT----KAVIDGPVRHQDSQGLWTLGAAAVGIG-
TH_2635|M.thermoresistible__bu      ITVAVVSLSATVAIPLMT----KAVIDGPVRQQDQQGLWILGSAAMAVG-
MAV_1421|M.avium_104                MALQVISNLASLYLPTVN----AAIIDEGVAKGDTSTIVRLGVVMLGVT-
MUL_4010|M.ulcerans_Agy99           MALQLISTLASLYLPTVN----AAIIDDGVAKGDTNTIIRLGVVMLGVT-
MAB_1415c|M.abscessus_ATCC_199      VTLQIISTLASLYLPTVN----AAIIDDGVAHGDTRTIARLGAVMLGVT-
MLBr_01113|M.leprae_Br4923          ITLGITGTAIGIIVPWVLGHTTDLLFNGVIGRQLPKGISKTQAVAAARTR
                                    .   : .    : :* :       :::  :       :     .  .   

Mb0200|M.bovis_AF2122/97            ------------------------------------GATYLLTYVRRYYG
Rv0194|M.tuberculosis_H37Rv         ------------------------------------GATYLLMYVRRYYG
MMAR_5223|M.marinum_M               ------------------------------------VAIYFMTFVRRHYG
Mflv_1747|M.gilvum_PYR-GCK          ------------------------------------VTEAVLWFIRRWLV
Mvan_5006|M.vanbaalenii_PYR-1       ------------------------------------VTEAVLWFIRRWLV
MSMEG_5660|M.smegmatis_MC2_155      ------------------------------------ISEAVLWFIRRWLV
TH_2635|M.thermoresistible__bu      ------------------------------------ISEAVLMFIRRWLV
MAV_1421|M.avium_104                ------------------------------------AVQALCAVGAVYFG
MUL_4010|M.ulcerans_Agy99           ------------------------------------GLQVLCAVGAVYFG
MAB_1415c|M.abscessus_ATCC_199      ------------------------------------LVQITCSIGAVYFG
MLBr_01113|M.leprae_Br4923          GDNALADLLSGMNLVPGQGVDFVAVGRTLGLALSLYLVYTLLTWAQARLL
                                                                                      

Mb0200|M.bovis_AF2122/97            GRIAHLVQHDLRMDAFQALLRWDGRQQDRWSSGQLIVRTTNDLQLVQALL
Rv0194|M.tuberculosis_H37Rv         GRIAHLVQHDLRMDAFQALLRWDGRQQDRWSSGQLIVRTTNDLQLVQALL
MMAR_5223|M.marinum_M               GRIAHLVQHDLRVDAFATLMRWDGRQQDRWSSGQLIVRTTNDLELVQTLL
Mflv_1747|M.gilvum_PYR-GCK          ARATMGVEADIRKQLYARLQILPMSFHGRWQSGQLLSRIMNDLSTIRRFM
Mvan_5006|M.vanbaalenii_PYR-1       ARATMGVEADIRKQLYARLQILPMSFHGQWQSGQLLSRIMNDLSTIRRFM
MSMEG_5660|M.smegmatis_MC2_155      ARATMGVEADIRKDLYARLQILPMSFHGRWQSGQLLSRVMNDLSTIRRFM
TH_2635|M.thermoresistible__bu      ARATMGVEADIRKDLYARLQILPMSFHGRWQSGQLVSRVMNDLSTIRRLL
MAV_1421|M.avium_104                SRTGMGFGRDLRAAMFEHVITFSERETARFGAPTLLTRSTNDVRQIQYLV
MUL_4010|M.ulcerans_Agy99           ARTGTGFGRDLRAAMFEHVITFSERETARFGASTLLTRSTNDVRQIVFLV
MAB_1415c|M.abscessus_ATCC_199      SRTGMGFGRDMRSALFHHITGFSAEESARFGAPTLLTRTTNDVQQLQLLI
MLBr_01113|M.leprae_Br4923          NVTVQRIMFALRSDVEDKVHRLPLSYCDTRQRGELLSRVTNDIDNLQSSL
                                          .   :*      :               *: *  **:  :   :

Mb0200|M.bovis_AF2122/97            -FDVPNVLRHVLTLLLGVAVMTWLSVPLALLAVLLVPVIGLIAHRSRRLL
Rv0194|M.tuberculosis_H37Rv         -FDVPNVLRHVLTLLLGVAVMTWLSVPLALLAVLLVPVIGLIAHRSRRLL
MMAR_5223|M.marinum_M               -FDLPNVIRHLLTLLLCLAVMAWLSLPLALLVVLLVPLIGLVAHRSRRLL
Mflv_1747|M.gilvum_PYR-GCK          SFGLIFLMLNVLQITVVTVILLVMYWPLGVVVLVSIVPITLTVLHFQQEY
Mvan_5006|M.vanbaalenii_PYR-1       SFGLIFLMLNVLQITVVTAILLAMYWPLGVVVLVSIVPITLTVLHFQQEY
MSMEG_5660|M.smegmatis_MC2_155      SFGLVFLILNGLQITVVTAILLAMYWPLGVVVLVSIVPIAATVLHFEREY
TH_2635|M.thermoresistible__bu      SFGLVFLVLNGLQIAVVTSILLAMYWPLGVVALLSIVPITMTVLHFQRLY
MAV_1421|M.avium_104                QITATVLVTAPIMCLGGIVMAIHQEAALTWLLLISVPVMALTNYWVMSHM
MUL_4010|M.ulcerans_Agy99           QTTATVLVAAPIMSIGGIIMAVHQEAALTWLLLVSVPILALANYWIMTHM
MAB_1415c|M.abscessus_ATCC_199      QVTCTMLVTAPIMCVGGIAMAIHQNAGLSWLLMVSMPALGLANWYIVHSM
MLBr_01113|M.leprae_Br4923          SITLSQLLTSLLTVVAVLVVMVSVSPLLALVALLTVPMSLLATRAIAQRS
                                          ::   :       :       *  : :: :              

Mb0200|M.bovis_AF2122/97            AAATHCAQEHKAAVTGVVDAAVCGIRVVKAFGQEERETVKLVMASRALYA
Rv0194|M.tuberculosis_H37Rv         AAATHCAQEHKAAVTGVVDAAVCGIRVVKAFGQEERETVKLVTASRALYA
MMAR_5223|M.marinum_M               AVATEAAQERNAVVTGVVDAAVSGIHVVKAFGQQSQETVKLTTAGRALYA
Mflv_1747|M.gilvum_PYR-GCK          TRLSRLAQDQAGHVATHVEEAALGLRVVKSFGREDYVYDRFDEQLTDLYD
Mvan_5006|M.vanbaalenii_PYR-1       TRLSRLAQDQAGHVATHVEEAALGLRVIKSFGREDYVYERFDDQLTDLYD
MSMEG_5660|M.smegmatis_MC2_155      TRLSRLAQDQTGHVATHVEESALGLRVVKSFGREDYVFDRFDEQATRLYD
TH_2635|M.thermoresistible__bu      TRLSRQAQDETGHVATHVEEAALGVRVVKSFGRERYSYDRFDEQATRLFR
MAV_1421|M.avium_104                LPLFRRMQALIDGVNRVMRDQLSGVRVVRAFAREDFERDRFDRANATLSN
MUL_4010|M.ulcerans_Agy99           LPLFRSMQALIDGINRVLRDQLSGVRVVRAFTREPFERDRFAQANTALAS
MAB_1415c|M.abscessus_ATCC_199      LPIFRRMQRLIDGINRVMREQLSGIRVVRAFTREAVERKRFSAAVAEVSE
MLBr_01113|M.leprae_Br4923          QQLFVAQWTSAGRLNAHIEETYSGLTVVKTFGHQTAAREQFRNVNNDVYQ
                                                 :   :     *: *:::* ::     ::      :  

Mb0200|M.bovis_AF2122/97            AQLRVARLNAHFGPLLQTLPALGQMAVFALGGWMAAQGSITVGTFVAFWA
Rv0194|M.tuberculosis_H37Rv         AQLRVARLNAHFGPLLQTLPALGQMAVFALGGWMAAQGSITVGTFVAFWA
MMAR_5223|M.marinum_M               ARVRVARLNAYFGPLLQSLPAFGQMAVLAVGGWMAAQGTITVGTFVAFWS
Mflv_1747|M.gilvum_PYR-GCK          TQIDRVSVSAKFWTLLEIIPNLTLIVVLGFGAYAAGHGHVTMGTLVAFIT
Mvan_5006|M.vanbaalenii_PYR-1       TQVSRVSVSAKFWTLLEIIPNLTLIVVLGFGAYAAGHGYVTMGTLVAFIT
MSMEG_5660|M.smegmatis_MC2_155      TQVARVGVSAKFWTLLEVIPNLTLIVVLGFGAYAAGHGYVTMGTLVAFIT
TH_2635|M.thermoresistible__bu      TQVGRVEVSARFWTLLEIIPNLTLIVVLGFGAYAAGTGLVTMGTLVAFIT
MAV_1421|M.avium_104                TALAAGNWQALMLPVTTLTINVSSVALIWFGGLRIDHGQMQVGSLTAFLA
MUL_4010|M.ulcerans_Agy99           TALRAGNWQALMLPVTTLTINVSSVAVIWFGGLLIDQGRMQVGSLSAFLS
MAB_1415c|M.abscessus_ATCC_199      AALAAGRWQALMLPATSLVINTSSVALIWFGGLRIDQGQMQVGSLVAFLS
MLBr_01113|M.leprae_Br4923          ASFSAQFFSGLVSPATMFISNLGYVVVAALGGLQVATGHITLGNIQAFIQ
                                    : .     .. . .          :.:  .*.     * : :*.: **  

Mb0200|M.bovis_AF2122/97            CLTLLARPACDLAGMLTIAQQARAGAVRVLELIDSRPTLVDGTKPLSLEA
Rv0194|M.tuberculosis_H37Rv         CLTLLARPACDLAGMLTIAQQARAGAVRVLELIDSRPTLVDGTKPLSPEA
MMAR_5223|M.marinum_M               CLTLVSRPACDLAGMLTIAQQARTGAMRVFELIDSRPTLVDGTKQLPSST
Mflv_1747|M.gilvum_PYR-GCK          MMLSLVWPIASLGFLLSMTQESFTAANRIAEIFDAPREITDGPREQAPR-
Mvan_5006|M.vanbaalenii_PYR-1       MMLSLVWPIASLGFLLSMTQESFTAANRIAEIFDAPREITDGPRDQAPR-
MSMEG_5660|M.smegmatis_MC2_155      MMLSLVWPIASLGFLLSMTQESFTAANRIAEIFDAPREIVDGPITEAPR-
TH_2635|M.thermoresistible__bu      MMLSLVWPIASLGFLLSMTQESMTAANRIAEIFDAPIEITDGPITTPPR-
MAV_1421|M.avium_104                YFTQILMAVLMATMTLVVLPRASVCAERITEVLSTGAAVADPASPKSPPG
MUL_4010|M.ulcerans_Agy99           YFAQILMAVLMATMTLVVLPRAAVCAERITEVLSTPAALNNPQHPRFPAA
MAB_1415c|M.abscessus_ATCC_199      YFLQILMSMMMLTMLAVMVPRASACAERITEVFDTTGAITAPADPVRVAD
MLBr_01113|M.leprae_Br4923          YVRQFNMPLSQVAGIYNTLQSGLASAERVFDLLDEPEELPDPMLALPPPH
                                     .  .  .             . . * *: :::.    :           

Mb0200|M.bovis_AF2122/97            ----R--LSLEFQRVSFGYVA----------DRPVLREISLSVRAGETLA
Rv0194|M.tuberculosis_H37Rv         ----R--LSLEFQRVSFGYVA----------DRPVLREISLSVRAGETLA
MMAR_5223|M.marinum_M               ----P--VSLAFEQASFGYAA----------EHPVLRGIDLSVRPGETLA
Mflv_1747|M.gilvum_PYR-GCK          ------GGRLELVDVGFRFPD---------SDEWALRHVTVTVEPGETLA
Mvan_5006|M.vanbaalenii_PYR-1       ------GGRLEVVDVGFRFPDSA-------SGDWALRHVTVTVEPGETLA
MSMEG_5660|M.smegmatis_MC2_155      ------GGRLQLRDVGFKFPD---------SDEWVLRGVNLTVEPGETVA
TH_2635|M.thermoresistible__bu      ------RGRLELRDVGFKFPDSGGVGASGGQDTWVLRHVTVTVEPGETLA
MAV_1421|M.avium_104                ----AITGIVRLDRATFTYPG---------ADRPVLQDISLTARPGTTTA
MUL_4010|M.ulcerans_Agy99           ----GITGAVRLENITFSYPG---------ADCPVLQDISLSAPPGATTA
MAB_1415c|M.abscessus_ATCC_199      ----PYP-TVEFTRAGFRYPG---------AERAVLEEISFTAQPGMITA
MLBr_01113|M.leprae_Br4923          GQVPRINGRVEFQQVSFAYRT----------GTPVIDDLSMVVEPGSTVA
                                             : .    * :               .:  : . . .*   *

Mb0200|M.bovis_AF2122/97            VVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRELTLDSLRSAIGLVP
Rv0194|M.tuberculosis_H37Rv         VVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRELTLDSLRSAIGLVP
MMAR_5223|M.marinum_M               VVGPPGSGKSTLALLAMRCYDVTAGAVRVGGHDVRDLTLDSLRSAIGLVP
Mflv_1747|M.gilvum_PYR-GCK          LVGATGSGKSVLVGLLSRLYDVTEGEIRIDAQDIRELSLRALRETVATAF
Mvan_5006|M.vanbaalenii_PYR-1       LVGATGSGKSVLAGLLSRLYDVTEGEIRIDAQDIRELSLDALRRTVATAF
MSMEG_5660|M.smegmatis_MC2_155      LVGSTGSGKSVLAALFSRLYDVTEGQILIDGRDIRDLSLPALRRTVATAF
TH_2635|M.thermoresistible__bu      LVGPTGSGKSVLVSLLSRLYDVTEGQIRIDGIDIRELSLDALRRTVATAF
MAV_1421|M.avium_104                IVGSTGSGKSTLISLICRLYDVTGGAVQIDGIDVRDYRTERLWSAIGLVP
MUL_4010|M.ulcerans_Agy99           IVGSTGSGKSTLISLICRLYDVTGGTVLLDGIDVRDYQTERLWAAIGLVP
MAB_1415c|M.abscessus_ATCC_199      IVGATGCGKSTLLNLIPRLHDVTTGSVRVGGNDVRRYDPEDLWTVMGLVP
MLBr_01113|M.leprae_Br4923          IVGPTGAGKTTLVNLLMRFYDVDSGQILIDGVDITTVSRHALRSRIGMVL
                                    :**..*.**:.*  *  * :**  * : :.. *:       *   :. . 

Mb0200|M.bovis_AF2122/97            EDAVLFSGTIGANIAYGRP---DATPEQIATAARAAHIEEFVNTLPDGYQ
Rv0194|M.tuberculosis_H37Rv         EDAVLFSGTIGANIAYGRP---DATPEQIATAARAAHIEEFVNTLPDGYQ
MMAR_5223|M.marinum_M               EQAILFSGTIGENISYGRS---NVTLEQITAAARAAHIDEFVNTLPDGYA
Mflv_1747|M.gilvum_PYR-GCK          EDPTLFSMSVAENLRLGRP---DATDEDLRQAVEIAAAQ-FVYDLPFGLD
Mvan_5006|M.vanbaalenii_PYR-1       EDPTLFSMSVAENLRLGRP---EATDDDLRRAIDVAAAQ-FVYDLPFGLD
MSMEG_5660|M.smegmatis_MC2_155      EDPTLFSMSVAENLRLGRS---DATDDELEQAVEVAAAH-FVYDLPFGLD
TH_2635|M.thermoresistible__bu      EDPTLFSVSVEENLRLGRPPANPASDAELAEAIEIAAAE-FVHDLPYGLH
MAV_1421|M.avium_104                QRGYLFSGTVADNLRYGRA---DATEQQMWEALRVAAADDFVGAHPDGLH
MUL_4010|M.ulcerans_Agy99           QRGYLFSGTVADNLRYGKS---DATDEEMWEALRVAAAEEFVRAH--GLQ
MAB_1415c|M.abscessus_ATCC_199      QRGYLFSGTVESNLRYGKA---DATEDEMWAALEVAQAAGFVRQHAAGLQ
MLBr_01113|M.leprae_Br4923          QDAWLFDGTIAENIAYGRP---QASEDEVMEAAKAAYVDRFVHTLSAGYQ
                                    :   **. ::  *:  *:.    .:  ::  *   *    **     *  

Mb0200|M.bovis_AF2122/97            TAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSAVDAVIECGIQE
Rv0194|M.tuberculosis_H37Rv         TAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSAVDAVIECGIQE
MMAR_5223|M.marinum_M               TPVGAQGLTLSGGQRQRIALARALVGNPRLLIMDEPTSAVDAVIEASIQD
Mflv_1747|M.gilvum_PYR-GCK          TRIGEQGMSLSGGQRQRLSLARAILTRPRILVLDDTLSALDVHTEAVVEE
Mvan_5006|M.vanbaalenii_PYR-1       TRIGEQGMSLSGGQRQRISLARAILADPRILVLDDTLSALDVHTEAVVEE
MSMEG_5660|M.smegmatis_MC2_155      TRIGEQGMSLSGGQRQRLSLARAILAAPRILVLDDTLSALDVHTEARVTE
TH_2635|M.thermoresistible__bu      TRIGEQGMSLSGGQRQRLSLARAVLAAPTILVLDDTLSALDVHTEAVVTE
MAV_1421|M.avium_104                MRVAQGGINFSGGQRQRLAIARAVIRRPAIYLFDDSFAALDARTDSRVRA
MUL_4010|M.ulcerans_Agy99           MRVAQGGINFSGGQRQRLAIARAIIGRPAVYLFDDAFSALDVHTDARVRA
MAB_1415c|M.abscessus_ATCC_199      MPVSQGGINFSGGQRQRIAIARAVIRRPGIYLFDDAFSALDVHTDARLRA
MLBr_01113|M.leprae_Br4923          TRVSGDGDNISAGEKQLITIARAFLARPQLLILDEATSSIDTRTEALIAR
                                      :.  * .:*.*::* :::***.:  * : ::*:. :::*.  :. :  

Mb0200|M.bovis_AF2122/97            VLREAIADRTAVIFTRRRSMLTLADRVAVLDS-----GRLLDVGTPDEVW
Rv0194|M.tuberculosis_H37Rv         VLREAIADRTAVIFTRRRSMLTLADRVAVLDS-----GRLLDVGTPDEVW
MMAR_5223|M.marinum_M               VLREVLADRTAVIFTRRRSMLSLADRVAVLDS-----GHLLDIGTPEQLW
Mflv_1747|M.gilvum_PYR-GCK          ALRRVLHEVTGIVVAHRASTVLLADRVALLQN-----GTVTHVGTHAELL
Mvan_5006|M.vanbaalenii_PYR-1       SLRRVLHDVTAIVVAHRASTVLLADRVALLRN-----GTITHVGTHAELL
MSMEG_5660|M.smegmatis_MC2_155      ALSRVLSSVTGVIVAHRASTVLLADKVALLDRDAHGAGTVTHIGTHAELL
TH_2635|M.thermoresistible__bu      ALRRVLRDVTGIVVANRASTVLLADRVALLERVGPDGATITHVGTHAELL
MAV_1421|M.avium_104                ALREITCDATVIVVTQRVSIAATADQVVVIDD-----GKVAGAGTHDALL
MUL_4010|M.ulcerans_Agy99           SLRELATKSAIIIVTQRVSTAAQADQVIVIDD-----GRVVGAGTHDSLL
MAB_1415c|M.abscessus_ATCC_199      ALREVAADATVIVVAQRISTVADADQIVVLED-----GRVAATGTHAELT
MLBr_01113|M.leprae_Br4923          ATHDLLQDRTSFIIAHHLPTIRDADHILVVAA-----GKIVEQGSHAKLL
                                           . : .:.:.: .    **:: ::       . :   *:   : 

Mb0200|M.bovis_AF2122/97            ERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTNVHNPGP
Rv0194|M.tuberculosis_H37Rv         ERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTNVHNPGP
MMAR_5223|M.marinum_M               GRCSRYRELLSPATDPLRSLAFEDGVPEPESEP-----EAIDVAADATGP
Mflv_1747|M.gilvum_PYR-GCK          AGVPEYRYLLAADDELDDGSERE---------------------CDWERD
Mvan_5006|M.vanbaalenii_PYR-1       ANVPEYRYLLAADDELDDGSERE---------------------CDWEEQ
MSMEG_5660|M.smegmatis_MC2_155      AEVPQYRYLLAADDELDDDTERT---------------------CEWEDD
TH_2635|M.thermoresistible__bu      ADVPQYRYLLAADPDLDDGAEPTPXXXVRAGTVATGSRSPTPTRCHPRRG
MAV_1421|M.avium_104                TDCAVYAEFADSQSVGAVPSGHTGSTP-----------------------
MUL_4010|M.ulcerans_Agy99           IDCPTYAEFAVSQSVTADIRGVS---------------------------
MAB_1415c|M.abscessus_ATCC_199      RRCGTYREICDSQAVFA---------------------------------
MLBr_01113|M.leprae_Br4923          ARRGAYYRMTQA--------------------------------------
                                         *  :  .                                      

Mb0200|M.bovis_AF2122/97            HDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRHGIDVGI
Rv0194|M.tuberculosis_H37Rv         HDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRHGIDVGI
MMAR_5223|M.marinum_M               SDHSPKPDLLRRLLHDFRGPLIVSLLLVALETGAGLLPPLLIRHGIDVGI
Mflv_1747|M.gilvum_PYR-GCK          EERARL---------DHEVLDGDVREREMLERRS----------------
Mvan_5006|M.vanbaalenii_PYR-1       EERARL---------DRDEECARV-DHEVLGRRA----------------
MSMEG_5660|M.smegmatis_MC2_155      EDLERLR-----RVHDERAAIDGLDEPEYLGQEVQRR-------------
TH_2635|M.thermoresistible__bu      SRRCRSRPPAAPRRPPRRPTSSGCRPAPGRSRRIRHRADGRPGSSRRRSA
MAV_1421|M.avium_104                --------------------------------------------------
MUL_4010|M.ulcerans_Agy99           --------------------------------------------------
MAB_1415c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0200|M.bovis_AF2122/97            RRHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQVLFRLRSVVFA
Rv0194|M.tuberculosis_H37Rv         RRHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQVLFRLRSVVFA
MMAR_5223|M.marinum_M               RQHVLTALWWAALAGAAIVAIRLVAQWGSAVVAGTAGEKALFRLRSLVFA
Mflv_1747|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5006|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5660|M.smegmatis_MC2_155      --------------------------------------------------
TH_2635|M.thermoresistible__bu      GRRPSPSPRDSRGSDRGVPVAYTGYMSCSSRLVPVVSTTFAPMLSVQM--
MAV_1421|M.avium_104                --------------------------------------------------
MUL_4010|M.ulcerans_Agy99           --------------------------------------------------
MAB_1415c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0200|M.bovis_AF2122/97            HAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVAVISVVTLVGI
Rv0194|M.tuberculosis_H37Rv         HAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVAVISVVTLVGI
MMAR_5223|M.marinum_M               HAQRLDLDAFEDNGDSQIITAVTADVDAIVAFLRTGLVIAIVSLVTAVGI
Mflv_1747|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5006|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5660|M.smegmatis_MC2_155      --------------------------------------------------
TH_2635|M.thermoresistible__bu      --------------------------------------------------
MAV_1421|M.avium_104                --------------------------------------------------
MUL_4010|M.ulcerans_Agy99           --------------------------------------------------
MAB_1415c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0200|M.bovis_AF2122/97            LVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRARHRLGTVTAT
Rv0194|M.tuberculosis_H37Rv         LVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRARHRLGTVTAT
MMAR_5223|M.marinum_M               LAALLAINAKLALLIFATLPMLGLATWQFRRASSWTYRQARQRLGTVTAT
Mflv_1747|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5006|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5660|M.smegmatis_MC2_155      --------------------------------------------------
TH_2635|M.thermoresistible__bu      --------------------------------------------------
MAV_1421|M.avium_104                --------------------------------------------------
MUL_4010|M.ulcerans_Agy99           --------------------------------------------------
MAB_1415c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0200|M.bovis_AF2122/97            LREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQRLLALYYPFVA
Rv0194|M.tuberculosis_H37Rv         LREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQRLLALYYPFVA
MMAR_5223|M.marinum_M               LREYSAGLRIAQAYRAEYVGFQTYFAHSDDYRRLRVRGQRLLALYFPLVP
Mflv_1747|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5006|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5660|M.smegmatis_MC2_155      --------------------------------------------------
TH_2635|M.thermoresistible__bu      --------------------------------------------------
MAV_1421|M.avium_104                --------------------------------------------------
MUL_4010|M.ulcerans_Agy99           --------------------------------------------------
MAB_1415c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0200|M.bovis_AF2122/97            LLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYTPIGELAQMFD
Rv0194|M.tuberculosis_H37Rv         LLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYTPIGELAQMFD
MMAR_5223|M.marinum_M               LTCSLATTLVLFEGGRDVQAGVLSVGALVTYLLYVEMLFAPVDKLSQMFD
Mflv_1747|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5006|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5660|M.smegmatis_MC2_155      --------------------------------------------------
TH_2635|M.thermoresistible__bu      --------------------------------------------------
MAV_1421|M.avium_104                --------------------------------------------------
MUL_4010|M.ulcerans_Agy99           --------------------------------------------------
MAB_1415c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0200|M.bovis_AF2122/97            DYQRAAVAAGRIRSLLSTRTPSSPAARPVGTLRGEVVFDAVHYSYRTREV
Rv0194|M.tuberculosis_H37Rv         DYQRAAVAAGRIRSLLSTRTPSSPAARPVGTLRGEVVFDAVHYSYRTREV
MMAR_5223|M.marinum_M               EYQRAAVAVGRIRSLLNTPTAFSPSAAPVGTLRGEIEFDAVHFRYPTRDA
Mflv_1747|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5006|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5660|M.smegmatis_MC2_155      --------------------------------------------------
TH_2635|M.thermoresistible__bu      --------------------------------------------------
MAV_1421|M.avium_104                --------------------------------------------------
MUL_4010|M.ulcerans_Agy99           --------------------------------------------------
MAB_1415c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0200|M.bovis_AF2122/97            PALAGINLRIPAGQTVVFVGSTGSGKSTLIKLVARFYDPTHGTVRVDGCD
Rv0194|M.tuberculosis_H37Rv         PALAGINLRIPAGQTVVFVGSTGSGKSTLIKLVARFYDPTHGTVRVDGCD
MMAR_5223|M.marinum_M               PALAGINLRIPAGQTVVFVGSTGSGKSTLMKLVSRFYDPTDGIIRVDGCD
Mflv_1747|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5006|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5660|M.smegmatis_MC2_155      --------------------------------------------------
TH_2635|M.thermoresistible__bu      --------------------------------------------------
MAV_1421|M.avium_104                --------------------------------------------------
MUL_4010|M.ulcerans_Agy99           --------------------------------------------------
MAB_1415c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0200|M.bovis_AF2122/97            LREFDVDGYRNRLGIVTQEQYVFAGTVRDAIAYGRPDATDAQVERAAREV
Rv0194|M.tuberculosis_H37Rv         LREFDVDGYRNRLGIVTQEQYVFAGTVRDAIAYGRPDATDAQVERAAREV
MMAR_5223|M.marinum_M               LREFDIDGYRSRLSIVAQEPYLFAGTVRDAIAYGRPDATDAQVERAAREV
Mflv_1747|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5006|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5660|M.smegmatis_MC2_155      --------------------------------------------------
TH_2635|M.thermoresistible__bu      --------------------------------------------------
MAV_1421|M.avium_104                --------------------------------------------------
MUL_4010|M.ulcerans_Agy99           --------------------------------------------------
MAB_1415c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0200|M.bovis_AF2122/97            GAHPMITALDNGYLHQVTAGGRNLSAGQLQLLALARARLVDPDILLLDEA
Rv0194|M.tuberculosis_H37Rv         GAHPMITALDNGYLHQVTAGGRNLSAGQLQLLALARARLVDPDILLLDEA
MMAR_5223|M.marinum_M               GAHPMIAALDGGYQHEVAAGGRNLSAGQLQLLALARARLVDSDILLLDEA
Mflv_1747|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5006|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5660|M.smegmatis_MC2_155      --------------------------------------------------
TH_2635|M.thermoresistible__bu      --------------------------------------------------
MAV_1421|M.avium_104                --------------------------------------------------
MUL_4010|M.ulcerans_Agy99           --------------------------------------------------
MAB_1415c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0200|M.bovis_AF2122/97            TVALDPATEAVVQRATLTLAARRTTLIVAHGLAIAEHADRIVVLEHGTVV
Rv0194|M.tuberculosis_H37Rv         TVALDPATEAVVQRATLTLAARRTTLIVAHGLAIAEHADRIVVLEHGTVV
MMAR_5223|M.marinum_M               TVALDPATEALVHWATLGLAADRTTLIIAHELAIAEFVDRIVVLEQGTIV
Mflv_1747|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5006|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5660|M.smegmatis_MC2_155      --------------------------------------------------
TH_2635|M.thermoresistible__bu      --------------------------------------------------
MAV_1421|M.avium_104                --------------------------------------------------
MUL_4010|M.ulcerans_Agy99           --------------------------------------------------
MAB_1415c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0200|M.bovis_AF2122/97            EDGAHTELLAAGGHYSRLWAAHTRLCSPEITQLQCIDA------------
Rv0194|M.tuberculosis_H37Rv         EDGAHTELLAAGGHYSRLWAAHTRLCSPEITQLQCIDA------------
MMAR_5223|M.marinum_M               EDGTHVELLAAGGRYAALWAAHSRVGRPSPSDDRPIPTELLVHSPDTDVL
Mflv_1747|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5006|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5660|M.smegmatis_MC2_155      --------------------------------------------------
TH_2635|M.thermoresistible__bu      --------------------------------------------------
MAV_1421|M.avium_104                --------------------------------------------------
MUL_4010|M.ulcerans_Agy99           --------------------------------------------------
MAB_1415c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------