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MRTNWWGRLSRYVLRYRRDLLLGLFASVVGTAITVMVPLVTKRVIDNAIAPDHRPLAPWALVLVAAAVAI YFMTFVRRHYGGRIAHLVQHDLRVDAFATLMRWDGRQQDRWSSGQLIVRTTNDLELVQTLLFDLPNVIRH LLTLLLCLAVMAWLSLPLALLVVLLVPLIGLVAHRSRRLLAVATEAAQERNAVVTGVVDAAVSGIHVVKA FGQQSQETVKLTTAGRALYAARVRVARLNAYFGPLLQSLPAFGQMAVLAVGGWMAAQGTITVGTFVAFWS CLTLVSRPACDLAGMLTIAQQARTGAMRVFELIDSRPTLVDGTKQLPSSTPVSLAFEQASFGYAAEHPVL RGIDLSVRPGETLAVVGPPGSGKSTLALLAMRCYDVTAGAVRVGGHDVRDLTLDSLRSAIGLVPEQAILF SGTIGENISYGRSNVTLEQITAAARAAHIDEFVNTLPDGYATPVGAQGLTLSGGQRQRIALARALVGNPR LLIMDEPTSAVDAVIEASIQDVLREVLADRTAVIFTRRRSMLSLADRVAVLDSGHLLDIGTPEQLWGRCS RYRELLSPATDPLRSLAFEDGVPEPESEPEAIDVAADATGPSDHSPKPDLLRRLLHDFRGPLIVSLLLVA LETGAGLLPPLLIRHGIDVGIRQHVLTALWWAALAGAAIVAIRLVAQWGSAVVAGTAGEKALFRLRSLVF AHAQRLDLDAFEDNGDSQIITAVTADVDAIVAFLRTGLVIAIVSLVTAVGILAALLAINAKLALLIFATL PMLGLATWQFRRASSWTYRQARQRLGTVTATLREYSAGLRIAQAYRAEYVGFQTYFAHSDDYRRLRVRGQ RLLALYFPLVPLTCSLATTLVLFEGGRDVQAGVLSVGALVTYLLYVEMLFAPVDKLSQMFDEYQRAAVAV GRIRSLLNTPTAFSPSAAPVGTLRGEIEFDAVHFRYPTRDAPALAGINLRIPAGQTVVFVGSTGSGKSTL MKLVSRFYDPTDGIIRVDGCDLREFDIDGYRSRLSIVAQEPYLFAGTVRDAIAYGRPDATDAQVERAARE VGAHPMIAALDGGYQHEVAAGGRNLSAGQLQLLALARARLVDSDILLLDEATVALDPATEALVHWATLGL AADRTTLIIAHELAIAEFVDRIVVLEQGTIVEDGTHVELLAAGGRYAALWAAHSRVGRPSPSDDRPIPTE LLVHSPDTDVL
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_5223 | - | - | 100% (1201) | drug-transport transmembrane ATP-binding protein ABC transporter |
M. marinum M | MMAR_4148 | - | 1e-72 | 31.68% (625) | transmembrane ATP-binding protein ABC transporter |
M. marinum M | MMAR_3283 | - | 3e-70 | 32.47% (582) | drug-transport transmembrane ATP-binding protein ABC |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0200 | - | 0.0 | 77.03% (1184) | drugs-transport transmembrane ATP-binding protein ABC transporter |
M. gilvum PYR-GCK | Mflv_1748 | - | 1e-106 | 40.07% (589) | ABC transporter related |
M. tuberculosis H37Rv | Rv0194 | - | 0.0 | 77.11% (1184) | drugs-transport transmembrane ATP-binding protein ABC transporter |
M. leprae Br4923 | MLBr_01113 | - | 2e-70 | 34.84% (465) | putative ABC transporter, ATP-binding component |
M. abscessus ATCC 19977 | MAB_1414c | - | 7e-75 | 36.03% (469) | ABC transporter ATP-binding protein |
M. avium 104 | MAV_1420 | - | 1e-70 | 35.98% (478) | ABC transporter |
M. smegmatis MC2 155 | MSMEG_5659 | - | 1e-104 | 38.80% (598) | ABC transporter, ATP-binding protein |
M. thermoresistible (build 8) | TH_3634 | - | 1e-97 | 41.34% (491) | PUTATIVE ABC transporter, ATP-binding protein |
M. ulcerans Agy99 | MUL_4011 | - | 9e-73 | 31.68% (625) | transmembrane ATP-binding protein ABC transporter |
M. vanbaalenii PYR-1 | Mvan_5005 | - | 1e-104 | 40.58% (589) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1414c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAVA Rv0194|M.tuberculosis_H37Rv MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAIA MMAR_5223|M.marinum_M MRTNWWGRLSRYVLRYRRDLLLGLFASVVGTAITVMVPLVTKRVIDNAIA Mflv_1748|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5005|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5659|M.smegmatis_MC2_155 -------------------------------------------------- TH_3634|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1414c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 ADHRPLAPWAVVLVAAAGATYLLTYVRRYYGGRIAHLVQHDLRMDAFQAL Rv0194|M.tuberculosis_H37Rv ADHRPLAPWAVVLVAAAGATYLLMYVRRYYGGRIAHLVQHDLRMDAFQAL MMAR_5223|M.marinum_M PDHRPLAPWALVLVAAAVAIYFMTFVRRHYGGRIAHLVQHDLRVDAFATL Mflv_1748|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5005|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5659|M.smegmatis_MC2_155 -------------------------------------------------- TH_3634|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1414c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 LRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAV Rv0194|M.tuberculosis_H37Rv LRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAV MMAR_5223|M.marinum_M MRWDGRQQDRWSSGQLIVRTTNDLELVQTLLFDLPNVIRHLLTLLLCLAV Mflv_1748|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5005|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5659|M.smegmatis_MC2_155 -------------------------------------------------- TH_3634|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1414c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 MTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDA Rv0194|M.tuberculosis_H37Rv MTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDA MMAR_5223|M.marinum_M MAWLSLPLALLVVLLVPLIGLVAHRSRRLLAVATEAAQERNAVVTGVVDA Mflv_1748|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5005|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5659|M.smegmatis_MC2_155 -------------------------------------------------- TH_3634|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1414c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 AVCGIRVVKAFGQEERETVKLVMASRALYAAQLRVARLNAHFGPLLQTLP Rv0194|M.tuberculosis_H37Rv AVCGIRVVKAFGQEERETVKLVTASRALYAAQLRVARLNAHFGPLLQTLP MMAR_5223|M.marinum_M AVSGIHVVKAFGQQSQETVKLTTAGRALYAARVRVARLNAYFGPLLQSLP Mflv_1748|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5005|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5659|M.smegmatis_MC2_155 -------------------------------------------------- TH_3634|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1414c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 ALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQ Rv0194|M.tuberculosis_H37Rv ALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQ MMAR_5223|M.marinum_M AFGQMAVLAVGGWMAAQGTITVGTFVAFWSCLTLVSRPACDLAGMLTIAQ Mflv_1748|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5005|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5659|M.smegmatis_MC2_155 -------------------------------------------------- TH_3634|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1414c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 QARAGAVRVLELIDSRPTLVDGTKPLSLEARLSLEFQRVSFGYVADRPVL Rv0194|M.tuberculosis_H37Rv QARAGAVRVLELIDSRPTLVDGTKPLSPEARLSLEFQRVSFGYVADRPVL MMAR_5223|M.marinum_M QARTGAMRVFELIDSRPTLVDGTKQLPSSTPVSLAFEQASFGYAAEHPVL Mflv_1748|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5005|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5659|M.smegmatis_MC2_155 -------------------------------------------------- TH_3634|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1414c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 REISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRE Rv0194|M.tuberculosis_H37Rv REISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRE MMAR_5223|M.marinum_M RGIDLSVRPGETLAVVGPPGSGKSTLALLAMRCYDVTAGAVRVGGHDVRD Mflv_1748|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5005|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5659|M.smegmatis_MC2_155 -------------------------------------------------- TH_3634|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1414c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 LTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE Rv0194|M.tuberculosis_H37Rv LTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE MMAR_5223|M.marinum_M LTLDSLRSAIGLVPEQAILFSGTIGENISYGRSNVTLEQITAAARAAHID Mflv_1748|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5005|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5659|M.smegmatis_MC2_155 -------------------------------------------------- TH_3634|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1414c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSA Rv0194|M.tuberculosis_H37Rv EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSA MMAR_5223|M.marinum_M EFVNTLPDGYATPVGAQGLTLSGGQRQRIALARALVGNPRLLIMDEPTSA Mflv_1748|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5005|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5659|M.smegmatis_MC2_155 -------------------------------------------------- TH_3634|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 --------MTMAT-------APA-TRSCDFYCTIRRLLKQLVPQRRLS-- MUL_4011|M.ulcerans_Agy99 --------MTAALNQRPRGGAPAPTRSRDFWGSATRLVKRLAPQRRRS-- MAV_1420|M.avium_104 --------MTTTTRPAPP--APA-GRSRDFWGSAARLVKQLAPQRRTA-- MAB_1414c|M.abscessus_ATCC_199 --------MTRAIGFRGVQQGPA-ERSRDFRGTAIRMVKRLAPQRFLT-- Mb0200|M.bovis_AF2122/97 VDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVG Rv0194|M.tuberculosis_H37Rv VDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVG MMAR_5223|M.marinum_M VDAVIEASIQDVLREVLADRTAVIFTRRRSMLSLADRVAVLDSGHLLDIG Mflv_1748|M.gilvum_PYR-GCK -------------------------------MTETNWRGKFDE------- Mvan_5005|M.vanbaalenii_PYR-1 ------------------------------MSADGEWRGKYDE------- MSMEG_5659|M.smegmatis_MC2_155 -------------------------------MSVTDWRGRLQE------- TH_3634|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 ---------------LTVITLGITGTAIGIIVPWVLGHTT---------- MUL_4011|M.ulcerans_Agy99 ---------------LAVIALGIVGTAIGVAVPRILGHAA---------- MAV_1420|M.avium_104 ---------------IAVITLGIAGTVIGVMVPRILGHAT---------- MAB_1414c|M.abscessus_ATCC_199 ---------------ATVITLSMIGIAIGVIGPRILGHAT---------- Mb0200|M.bovis_AF2122/97 TPDEVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTN Rv0194|M.tuberculosis_H37Rv TPDEVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTN MMAR_5223|M.marinum_M TPEQLWGRCSRYRELLSPATDPLRSLAFEDGVPEPESEP-----EAIDVA Mflv_1748|M.gilvum_PYR-GCK -----------------SAD-----LPIDETVPRQREAR----------- Mvan_5005|M.vanbaalenii_PYR-1 -----------------HTD-----LPIDETVPRRREAR----------- MSMEG_5659|M.smegmatis_MC2_155 -----------------EQDPNNDNLPIDESIPLRREAR----------- TH_3634|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 ------------DLLFNGVIGRQLPKGISKTQAVAAARTRGDNALADLLS MUL_4011|M.ulcerans_Agy99 ------------DLLFNGVIGRQLPAGITKAQAIAGARARGDNTFAELLS MAV_1420|M.avium_104 ------------DLLFNGVVGRQLPAGISKAQAVAAARSRGQNTFADLLS MAB_1414c|M.abscessus_ATCC_199 ------------DLLFNGVIGRQLPAGQSREQAVETARARGDGQFAQMLS Mb0200|M.bovis_AF2122/97 VHNPGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRH Rv0194|M.tuberculosis_H37Rv VHNPGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRH MMAR_5223|M.marinum_M ADATGPSDHSPKPDLLRRLLHDFRGPLIVSLLLVALETGAGLLPPLLIRH Mflv_1748|M.gilvum_PYR-GCK -------------ALLGSLLRPYRWAVVLLAVVVVVENAARLSVPILVQK Mvan_5005|M.vanbaalenii_PYR-1 -------------SLLYLLLRPYRWVVLALAVVVVVENAARLSVPLLVQK MSMEG_5659|M.smegmatis_MC2_155 -------------SLLISLLRPYRWIVAVLALVVIVENAARLSVPVLVQR TH_3634|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 GMNLVPG---QGVDFVAVGRTLGLALSLYLVYTLLTWAQARLLNVTVQRI MUL_4011|M.ulcerans_Agy99 GMKVTPG---QGVDFGAVVRTLALALALYLIASLLIWGQARLLNVTVQRT MAV_1420|M.avium_104 GMNVVPG---RGVDFGAVARTLALALLLYLVSALLIWVQARLLNRTVQRT MAB_1414c|M.abscessus_ATCC_199 GMNVIPG---QGVDFHAIGMTLALALSLYLIAGMLAWVQARLLNVTVQRT Mb0200|M.bovis_AF2122/97 GIDVGIR----RHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQV Rv0194|M.tuberculosis_H37Rv GIDVGIR----RHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQV MMAR_5223|M.marinum_M GIDVGIR----QHVLTALWWAALAGAAIVAIRLVAQWGSAVVAGTAGEKA Mflv_1748|M.gilvum_PYR-GCK GIDDGIPPLLEGGPAITLMTIVATLCGVVVVQAVGRMYFLRRSGRIGQKV Mvan_5005|M.vanbaalenii_PYR-1 GIDDGIPPLLAGERATTLLTIVAALCGVVVVQACSRMYFLRRSGRIGQKV MSMEG_5659|M.smegmatis_MC2_155 GIDHGIPPILAGGPARELMVIVATLCAVVLVQATSRMFFLRRSGRVGQKV TH_3634|M.thermoresistible__bu ------------------------------------MYFLRRSGRIGQEV . :. MLBr_01113|M.leprae_Br4923 MFALRSDVEDKVHRLPLSYCDTRQRGELLSRVTNDIDNLQSSLSITLSQL MUL_4011|M.ulcerans_Agy99 VAALRADVEHKLHRLPLSYFDGRQRGELLSRVTNDIDNIQSSLSMTISQL MAV_1420|M.avium_104 MVALRSAVEDKVHRLPLAYFDGRQRGELLSRVTNDIDNIQSSLSMTISQL MAB_1414c|M.abscessus_ATCC_199 VVALRTEVENKIHRLPLSYFDSRQRGEILSRVTNDVDNIQTSLQMSINQL Mb0200|M.bovis_AF2122/97 LFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVA Rv0194|M.tuberculosis_H37Rv LFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVA MMAR_5223|M.marinum_M LFRLRSLVFAHAQRLDLDAFEDNGDSQIITAVTADVDAIVAFLRTGLVIA Mflv_1748|M.gilvum_PYR-GCK LLELRRRVFRHFGRLDIAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL Mvan_5005|M.vanbaalenii_PYR-1 LLELRRRVFRHFGRLDIAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL MSMEG_5659|M.smegmatis_MC2_155 LLELRRRVFRHFQRLDLAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL TH_3634|M.thermoresistible__bu LLELRRRLFRHFQRLDVAFHERYTSGRVVSRSTNDVEAIQDMLETGFDSL : ** : : ** : : ..::: * *:: : * : MLBr_01113|M.leprae_Br4923 LTSLLTVVAVLVVMVSVSPLLALVALLTVPMSLLATRAIAQRSQQLFVAQ MUL_4011|M.ulcerans_Agy99 VTAILTVVAVLSMMVWISPLLALITLLTVPLSLLVTRAITRRSQRLFVAH MAV_1420|M.avium_104 LTSVLTVLTVLAMMLSISPLLAGITLLTVPLSLLATRVIVRRSQRLFVAQ MAB_1414c|M.abscessus_ATCC_199 LSSMLTLVAVLAMMLSISPLLAVITLATVPLSLWVTRTIARRSQRLFVAQ Mb0200|M.bovis_AF2122/97 VISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRA Rv0194|M.tuberculosis_H37Rv VISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRA MMAR_5223|M.marinum_M IVSLVTAVGILAALLAINAKLALLIFATLPMLGLATWQFRRASSWTYRQA Mflv_1748|M.gilvum_PYR-GCK ITAVLTMVGTAVLLVVLDVKLGLMCLVAFPVLVLLVWWFQRESSKTYREV Mvan_5005|M.vanbaalenii_PYR-1 ITAVLTLVGTAVLLVVLDVKLGLMCLAAFPILVLLVMWFRRESSKTYREV MSMEG_5659|M.smegmatis_MC2_155 ITAVLTLFGTAVLLVVLDWRLGLMCLAAFPILVALVWWFRNESARTYRKV TH_3634|M.thermoresistible__bu ITAVLTLGGTAILLVTLDVRLGLMCLGAFPVLIALVWWFREESAKTYRKV : :::* :: : * : : :.*: . : . * : MLBr_01113|M.leprae_Br4923 WTSAGRLNAHIEETYSGLTVVKTFGHQTAAREQFRNVNNDVYQASFSAQF MUL_4011|M.ulcerans_Agy99 WTSTGRLNAHIEETYSGFTVVKTFGHQAAAREQFHNLNDDVYQASFGAQL MAV_1420|M.avium_104 WTSVGRLNAHIEETYSGFTVVQTFGHRAAARDRFRALNDEVYRASFGAQF MAB_1414c|M.abscessus_ATCC_199 WANTGKLNAHIEETYSGFTIVKTYGHRAEAEAIFADRNAEVYRSAFGAQF Mb0200|M.bovis_AF2122/97 RHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQR Rv0194|M.tuberculosis_H37Rv RHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQR MMAR_5223|M.marinum_M RQRLGTVTATLREYSAGLRIAQAYRAEYVGFQTYFAHSDDYRRLRVRGQR Mflv_1748|M.gilvum_PYR-GCK REISALVIVQFVETMTGIKAVQAYRREPRNQQIFEDVADRYREINERTFK Mvan_5005|M.vanbaalenii_PYR-1 REISALVIVQFVETMTGIKAVQAYRREPRNQQIFEDIADRYRVINEKTFK MSMEG_5659|M.smegmatis_MC2_155 RESAALVIVQFVETMTGIKAVQAYRREPRNQEIFSDIADDYREINEKTFK TH_3634|M.thermoresistible__bu RESAALVIVQFVETMTGIKAVQAYRREPRNQEIFEQVADDYREINEKTLR . : . : * :*: .::: . : MLBr_01113|M.leprae_Br4923 FSGLVSPATMFISNLGYVVVAALGGLQVATGHITLGNIQAFIQYVRQFNM MUL_4011|M.ulcerans_Agy99 LSALVQPATTFIGNLGYVAVAVMGGLQVATGQITLGSVQAFIQYVRQFNT MAV_1420|M.avium_104 FSGLVAPATAVIGNLGYAAVAVLGGLQVATGQITLGNIQAFIQYVRQFNS MAB_1414c|M.abscessus_ATCC_199 FSGLVSPATAFVGNLSYVAVAVVGGLKVASGGLTLGSIQAFSQYVRQFNQ Mb0200|M.bovis_AF2122/97 LLALYYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYT Rv0194|M.tuberculosis_H37Rv LLALYYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYT MMAR_5223|M.marinum_M LLALYFPLVPLTCSLATTLVLFEGGRDVQAGVLSVGALVTYLLYVEMLFA Mflv_1748|M.gilvum_PYR-GCK LLAVFMPGVKLVGNLTTGVVLLYGGYRALHGEMTIGTLTAFLLYLRMFFE Mvan_5005|M.vanbaalenii_PYR-1 LLAVFMPGVKLVGNLTTGVVLLYGGYRVLHGEMTIGTLAAFLLYLRMFFE MSMEG_5659|M.smegmatis_MC2_155 LLAIFMPGVKLVGNITTGVVLIYGGYRVLNDQMTIGTLAAFLLYLRMFFE TH_3634|M.thermoresistible__bu LLAIFMPGVRLVGNITTGVVLLYGGYLVLNDQMTIGTLTAFLLYLRMFFE : .: * . . .: * *. . . :::* : :: *:. : MLBr_01113|M.leprae_Br4923 PLSQVAGIYNTLQSGLASAERVFDLLDEPEELPDPMLALPPPH----GQV MUL_4011|M.ulcerans_Agy99 PVSQVAAMYNSLQSGVASAERVFELLDEPEEAADPASALQPPVS-RTGRA MAV_1420|M.avium_104 PLSQLAGMYNTLQSGVASAERVFALLDEPEEPPDAPPEEKPTAPGPAGRD MAB_1414c|M.abscessus_ATCC_199 PLTQVAAMYNTLQSGLASAERVFELLDADEETPDPLAAATAPTG------ Mb0200|M.bovis_AF2122/97 PIGELAQMFDDYQRAAVAAGRIRSLLSTRTPSSPAA---RPVG------- Rv0194|M.tuberculosis_H37Rv PIGELAQMFDDYQRAAVAAGRIRSLLSTRTPSSPAA---RPVG------- MMAR_5223|M.marinum_M PVDKLSQMFDEYQRAAVAVGRIRSLLNTPTAFSPSA---APVG------- Mflv_1748|M.gilvum_PYR-GCK PMQEISQFFNTFQSASSALEKLAGVLAEKPGISDPA---KPVR------V Mvan_5005|M.vanbaalenii_PYR-1 PMQEISQFFNTFQSAASALEKLAGVLAEKPGISDPP---HPVA------L MSMEG_5659|M.smegmatis_MC2_155 PMQEISQFFNTFQSASSALEKLAGVLAQRPGIADPE---RPVA------L TH_3634|M.thermoresistible__bu PMQEISQFFNTFQSAASALEKLAGVLAEEPAIKDPQ---HPVSP-----A *: ::: ::: * . : :: :* . . MLBr_01113|M.leprae_Br4923 PRINGRVEFQQVSFAYRT-GTPVIDDLSMVVEPGSTVAIVGPTGAGKTTL MUL_4011|M.ulcerans_Agy99 PALTGRVEFERVNFAYHP-GHPVIHDLSLVAEPGSTVAIVGPTGAGKTTL MAV_1420|M.avium_104 AGGGGRVEFAHVSFAYRP-GIRVIDDLSLVAEPGSTVAIVGPTGAGKTTL MAB_1414c|M.abscessus_ATCC_199 ---SVRVEFEDISFGYSP-GQPVIEGLSLRVEPGQTVAIVGPTGAGKTTL Mb0200|M.bovis_AF2122/97 -TLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGSGKSTL Rv0194|M.tuberculosis_H37Rv -TLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGSGKSTL MMAR_5223|M.marinum_M -TLRGEIEFDAVHFRYPTRDAPALAGINLRIPAGQTVVFVGSTGSGKSTL Mflv_1748|M.gilvum_PYR-GCK DEVRGEVALLDVHFAYVP-GRPVLPGLDLVIPAGQTVALVGTTGAGKTTI Mvan_5005|M.vanbaalenii_PYR-1 GEVRGEIALRDLTFEYVP-GRPVLPGLDLVIPAGQTVALVGTTGAGKTTI MSMEG_5659|M.smegmatis_MC2_155 HAVAGTITFDHVHFAYAP-GRPVLPDLTLTVPAGQTVALVGTTGAGKTTI TH_3634|M.thermoresistible__bu RPVRGEIAFHGVQFAYVP-GRPVIPELTLTVPAGQTVALVGTTGAGKTTI : : : : * . .: : : .*.**.:**.**:**:*: MLBr_01113|M.leprae_Br4923 VNLLMRFYDVDSGQILIDGVDITTVSRHALRSRIGMVLQDAWLFDGTIAE MUL_4011|M.ulcerans_Agy99 VNLLMRFYEVDSGRILVDGIDITTVSRQSLRSHIGMVLQDTWLFDGTISE MAV_1420|M.avium_104 VNLLMRFYDVDAGRISIDGVDIATMDRRALRSRIGMVLQDTWLFDGTIAE MAB_1414c|M.abscessus_ATCC_199 VNLLMRFYEVDSGRILLDGIDVSTMTRHDLRSRMGMVLQDTWLFGGTIVE Mb0200|M.bovis_AF2122/97 IKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRD Rv0194|M.tuberculosis_H37Rv IKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRD MMAR_5223|M.marinum_M MKLVSRFYDPTDGIIRVDGCDLREFDIDGYRSRLSIVAQEPYLFAGTVRD Mflv_1748|M.gilvum_PYR-GCK AKLITRFYDPGSGTVSLDGVDLRDMSQADLRRHVVMVTQENFMFGGTIAD Mvan_5005|M.vanbaalenii_PYR-1 AKLITRFYDPVAGTVMLDEIDLRDVAQAELRRHVVMVTQENFMFGGTVAD MSMEG_5659|M.smegmatis_MC2_155 AKLIARFYDPTSGTVTLDGVDLRDLSQSELRRHVVMVTQENFMFEGTVAD TH_3634|M.thermoresistible__bu ATLIARFYDPTAGSVTLDGIDLRDIAQSELRRHVVMVTQENFMFDGTVAD .*: ***: * : :* *: . * :: :* *: ::* **: : MLBr_01113|M.leprae_Br4923 NIAYGRPQASEDEVMEAAKAAYVDRFVHTLSAGYQTRVSGDGDNISAGEK MUL_4011|M.ulcerans_Agy99 NIAYGRPEASPDDIIQAAKAAYVDRFVHMLPASYQTRISGDGSNISAGEK MAV_1420|M.avium_104 NIGYGRPGAGDDEIVAAARAAYVDRFVQNLPDGYHTRVSGDGGNLSAGER MAB_1414c|M.abscessus_ATCC_199 NIAYGRPGASQEEILEAARAAYVDRFVRTLPDGYDTKIADDGGNISAGEK Mb0200|M.bovis_AF2122/97 AIAYGRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQL Rv0194|M.tuberculosis_H37Rv AIAYGRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQL MMAR_5223|M.marinum_M AIAYGRPDATDAQVERAAREVGAHPMIAALDGGYQHEVAAGGRNLSAGQL Mflv_1748|M.gilvum_PYR-GCK NIRFGRPGATDDEVRAAARAVGAHTFIDVLPDGYDTDVAKRGGRLSAGQR Mvan_5005|M.vanbaalenii_PYR-1 NIRFGRPDATDDEVRAAARAVGAHTFIGALPDGYDTDVAKRGGRLSAGQR MSMEG_5659|M.smegmatis_MC2_155 NIRFGRPDATDAQVRAAAEAVGADRFIATLPEGYGTDVAKRGGRLSAGQR TH_3634|M.thermoresistible__bu NIRFGRPEATDAEIAAAAEAVGADRFIAALPDGYHTDVAKRGSRLSAGQR * :*** * :: **. . .. :: * .* :: * .:***: MLBr_01113|M.leprae_Br4923 QLITIARAFLARPQLLILDEATSSIDTRTEALIARATHDLLQDRTSFIIA MUL_4011|M.ulcerans_Agy99 QLITIARAFLARPQLLILDEATSSVDTRTELLIARATAELRRDRTSFIIA MAV_1420|M.avium_104 QLITIARAFLARPQLLILDEATSSVDTRTEALIAHATRELRRDRTSFIIA MAB_1414c|M.abscessus_ATCC_199 QLITIARAFLARPQLLILDEATSSVDTRTELRIQRAMAELRRDRTSFIIA Mb0200|M.bovis_AF2122/97 QLLALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVA Rv0194|M.tuberculosis_H37Rv QLLALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVA MMAR_5223|M.marinum_M QLLALARARLVDSDILLLDEATVALDPATEALVHWATLGLAADRTTLIIA Mflv_1748|M.gilvum_PYR-GCK QLVAFARAFLADPAVLILDEATSSLDIPSERLVQRALETVLADRTAVVIA Mvan_5005|M.vanbaalenii_PYR-1 QLVAFARAFLADPAVLILDEATSSLDIPSERMVQRALETVLADRTAVVIA MSMEG_5659|M.smegmatis_MC2_155 QLIAFARAFLADPAVLILDEATSSLDIPSERMVQRALETVLADRTALVIA TH_3634|M.thermoresistible__bu QLIAFARAFLADPAVLILDEATSALDIPSERMVQRALRTVLADRTALVIA **:::*** *. . :*:***** ::* :* : * : **:.::* MLBr_01113|M.leprae_Br4923 HHLPTIRDADHILVVAAGKIVEQGSHAKLLARRGAYYRMTQA-------- MUL_4011|M.ulcerans_Agy99 HRLSTIRDADQILVVQAGQIVEHGTHAELLANRGAYYAMTRA-------- MAV_1420|M.avium_104 HRLSTIRDADRIAVIEAGRIFEQGTHAELLARRGVYYAMTQA-------- MAB_1414c|M.abscessus_ATCC_199 HRLSTIRDADRIVVLDGGRVTESGTHTELLARHGAYFAMTQS-------- Mb0200|M.bovis_AF2122/97 HGLAIAEHADRIVVLEHGTVVEDGAHTELLAAG-GHYSRLWAAHTRLCSP Rv0194|M.tuberculosis_H37Rv HGLAIAEHADRIVVLEHGTVVEDGAHTELLAAG-GHYSRLWAAHTRLCSP MMAR_5223|M.marinum_M HELAIAEFVDRIVVLEQGTIVEDGTHVELLAAG-GRYAALWAAHSRVGRP Mflv_1748|M.gilvum_PYR-GCK HRLSTVQIADRVLVLEHGRIVEDGPPEELTAREGGHYAALHRSWVQSLA- Mvan_5005|M.vanbaalenii_PYR-1 HRLSTVQIADRVLVLEHGRIVEDGAPDELTARDHGHYAALHRSWVQSLA- MSMEG_5659|M.smegmatis_MC2_155 HRLSTVQIADRVLVLEHGRIIEDGSPADLIGRTDGAYAALHRAWVDSLA- TH_3634|M.thermoresistible__bu HRLSTVEIADRVLVLERGRVVEDGPPGELIRRGEGRYAALHHAWLESLG- * *. . .*:: *: * : * *. .* : MLBr_01113|M.leprae_Br4923 ---------------------- MUL_4011|M.ulcerans_Agy99 ---------------------- MAV_1420|M.avium_104 ---------------------- MAB_1414c|M.abscessus_ATCC_199 ---------------------- Mb0200|M.bovis_AF2122/97 EITQLQCIDA------------ Rv0194|M.tuberculosis_H37Rv EITQLQCIDA------------ MMAR_5223|M.marinum_M SPSDDRPIPTELLVHSPDTDVL Mflv_1748|M.gilvum_PYR-GCK ---------------------- Mvan_5005|M.vanbaalenii_PYR-1 ---------------------- MSMEG_5659|M.smegmatis_MC2_155 ---------------------- TH_3634|M.thermoresistible__bu ----------------------