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M. marinum M MMAR_5223 (-)

annotation: drug-transport transmembrane ATP-binding protein ABC transporter
coordinates: 6309196 - 6312801
length: 1201

MRTNWWGRLSRYVLRYRRDLLLGLFASVVGTAITVMVPLVTKRVIDNAIAPDHRPLAPWALVLVAAAVAI
YFMTFVRRHYGGRIAHLVQHDLRVDAFATLMRWDGRQQDRWSSGQLIVRTTNDLELVQTLLFDLPNVIRH
LLTLLLCLAVMAWLSLPLALLVVLLVPLIGLVAHRSRRLLAVATEAAQERNAVVTGVVDAAVSGIHVVKA
FGQQSQETVKLTTAGRALYAARVRVARLNAYFGPLLQSLPAFGQMAVLAVGGWMAAQGTITVGTFVAFWS
CLTLVSRPACDLAGMLTIAQQARTGAMRVFELIDSRPTLVDGTKQLPSSTPVSLAFEQASFGYAAEHPVL
RGIDLSVRPGETLAVVGPPGSGKSTLALLAMRCYDVTAGAVRVGGHDVRDLTLDSLRSAIGLVPEQAILF
SGTIGENISYGRSNVTLEQITAAARAAHIDEFVNTLPDGYATPVGAQGLTLSGGQRQRIALARALVGNPR
LLIMDEPTSAVDAVIEASIQDVLREVLADRTAVIFTRRRSMLSLADRVAVLDSGHLLDIGTPEQLWGRCS
RYRELLSPATDPLRSLAFEDGVPEPESEPEAIDVAADATGPSDHSPKPDLLRRLLHDFRGPLIVSLLLVA
LETGAGLLPPLLIRHGIDVGIRQHVLTALWWAALAGAAIVAIRLVAQWGSAVVAGTAGEKALFRLRSLVF
AHAQRLDLDAFEDNGDSQIITAVTADVDAIVAFLRTGLVIAIVSLVTAVGILAALLAINAKLALLIFATL
PMLGLATWQFRRASSWTYRQARQRLGTVTATLREYSAGLRIAQAYRAEYVGFQTYFAHSDDYRRLRVRGQ
RLLALYFPLVPLTCSLATTLVLFEGGRDVQAGVLSVGALVTYLLYVEMLFAPVDKLSQMFDEYQRAAVAV
GRIRSLLNTPTAFSPSAAPVGTLRGEIEFDAVHFRYPTRDAPALAGINLRIPAGQTVVFVGSTGSGKSTL
MKLVSRFYDPTDGIIRVDGCDLREFDIDGYRSRLSIVAQEPYLFAGTVRDAIAYGRPDATDAQVERAARE
VGAHPMIAALDGGYQHEVAAGGRNLSAGQLQLLALARARLVDSDILLLDEATVALDPATEALVHWATLGL
AADRTTLIIAHELAIAEFVDRIVVLEQGTIVEDGTHVELLAAGGRYAALWAAHSRVGRPSPSDDRPIPTE
LLVHSPDTDVL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_5223--100% (1201)drug-transport transmembrane ATP-binding protein ABC transporter
M. marinum MMMAR_4148-1e-7231.68% (625) transmembrane ATP-binding protein ABC transporter
M. marinum MMMAR_3283-3e-7032.47% (582) drug-transport transmembrane ATP-binding protein ABC

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0200-0.077.03% (1184) drugs-transport transmembrane ATP-binding protein ABC transporter
M. gilvum PYR-GCKMflv_1748-1e-10640.07% (589) ABC transporter related
M. tuberculosis H37RvRv0194-0.077.11% (1184) drugs-transport transmembrane ATP-binding protein ABC transporter
M. leprae Br4923MLBr_01113-2e-7034.84% (465) putative ABC transporter, ATP-binding component
M. abscessus ATCC 19977MAB_1414c-7e-7536.03% (469) ABC transporter ATP-binding protein
M. avium 104MAV_1420-1e-7035.98% (478) ABC transporter
M. smegmatis MC2 155MSMEG_5659-1e-10438.80% (598) ABC transporter, ATP-binding protein
M. thermoresistible (build 8)TH_3634-1e-9741.34% (491) PUTATIVE ABC transporter, ATP-binding protein
M. ulcerans Agy99MUL_4011-9e-7331.68% (625) transmembrane ATP-binding protein ABC transporter
M. vanbaalenii PYR-1Mvan_5005-1e-10440.58% (589) ABC transporter-related protein

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0200|M.bovis_AF2122/97            MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAVA
Rv0194|M.tuberculosis_H37Rv         MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAIA
MMAR_5223|M.marinum_M               MRTNWWGRLSRYVLRYRRDLLLGLFASVVGTAITVMVPLVTKRVIDNAIA
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0200|M.bovis_AF2122/97            ADHRPLAPWAVVLVAAAGATYLLTYVRRYYGGRIAHLVQHDLRMDAFQAL
Rv0194|M.tuberculosis_H37Rv         ADHRPLAPWAVVLVAAAGATYLLMYVRRYYGGRIAHLVQHDLRMDAFQAL
MMAR_5223|M.marinum_M               PDHRPLAPWALVLVAAAVAIYFMTFVRRHYGGRIAHLVQHDLRVDAFATL
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0200|M.bovis_AF2122/97            LRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAV
Rv0194|M.tuberculosis_H37Rv         LRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAV
MMAR_5223|M.marinum_M               MRWDGRQQDRWSSGQLIVRTTNDLELVQTLLFDLPNVIRHLLTLLLCLAV
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0200|M.bovis_AF2122/97            MTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDA
Rv0194|M.tuberculosis_H37Rv         MTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDA
MMAR_5223|M.marinum_M               MAWLSLPLALLVVLLVPLIGLVAHRSRRLLAVATEAAQERNAVVTGVVDA
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0200|M.bovis_AF2122/97            AVCGIRVVKAFGQEERETVKLVMASRALYAAQLRVARLNAHFGPLLQTLP
Rv0194|M.tuberculosis_H37Rv         AVCGIRVVKAFGQEERETVKLVTASRALYAAQLRVARLNAHFGPLLQTLP
MMAR_5223|M.marinum_M               AVSGIHVVKAFGQQSQETVKLTTAGRALYAARVRVARLNAYFGPLLQSLP
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0200|M.bovis_AF2122/97            ALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQ
Rv0194|M.tuberculosis_H37Rv         ALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQ
MMAR_5223|M.marinum_M               AFGQMAVLAVGGWMAAQGTITVGTFVAFWSCLTLVSRPACDLAGMLTIAQ
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0200|M.bovis_AF2122/97            QARAGAVRVLELIDSRPTLVDGTKPLSLEARLSLEFQRVSFGYVADRPVL
Rv0194|M.tuberculosis_H37Rv         QARAGAVRVLELIDSRPTLVDGTKPLSPEARLSLEFQRVSFGYVADRPVL
MMAR_5223|M.marinum_M               QARTGAMRVFELIDSRPTLVDGTKQLPSSTPVSLAFEQASFGYAAEHPVL
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0200|M.bovis_AF2122/97            REISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRE
Rv0194|M.tuberculosis_H37Rv         REISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRE
MMAR_5223|M.marinum_M               RGIDLSVRPGETLAVVGPPGSGKSTLALLAMRCYDVTAGAVRVGGHDVRD
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0200|M.bovis_AF2122/97            LTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE
Rv0194|M.tuberculosis_H37Rv         LTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE
MMAR_5223|M.marinum_M               LTLDSLRSAIGLVPEQAILFSGTIGENISYGRSNVTLEQITAAARAAHID
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0200|M.bovis_AF2122/97            EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSA
Rv0194|M.tuberculosis_H37Rv         EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSA
MMAR_5223|M.marinum_M               EFVNTLPDGYATPVGAQGLTLSGGQRQRIALARALVGNPRLLIMDEPTSA
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MLBr_01113|M.leprae_Br4923          --------MTMAT-------APA-TRSCDFYCTIRRLLKQLVPQRRLS--
MUL_4011|M.ulcerans_Agy99           --------MTAALNQRPRGGAPAPTRSRDFWGSATRLVKRLAPQRRRS--
MAV_1420|M.avium_104                --------MTTTTRPAPP--APA-GRSRDFWGSAARLVKQLAPQRRTA--
MAB_1414c|M.abscessus_ATCC_199      --------MTRAIGFRGVQQGPA-ERSRDFRGTAIRMVKRLAPQRFLT--
Mb0200|M.bovis_AF2122/97            VDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVG
Rv0194|M.tuberculosis_H37Rv         VDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVG
MMAR_5223|M.marinum_M               VDAVIEASIQDVLREVLADRTAVIFTRRRSMLSLADRVAVLDSGHLLDIG
Mflv_1748|M.gilvum_PYR-GCK          -------------------------------MTETNWRGKFDE-------
Mvan_5005|M.vanbaalenii_PYR-1       ------------------------------MSADGEWRGKYDE-------
MSMEG_5659|M.smegmatis_MC2_155      -------------------------------MSVTDWRGRLQE-------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MLBr_01113|M.leprae_Br4923          ---------------LTVITLGITGTAIGIIVPWVLGHTT----------
MUL_4011|M.ulcerans_Agy99           ---------------LAVIALGIVGTAIGVAVPRILGHAA----------
MAV_1420|M.avium_104                ---------------IAVITLGIAGTVIGVMVPRILGHAT----------
MAB_1414c|M.abscessus_ATCC_199      ---------------ATVITLSMIGIAIGVIGPRILGHAT----------
Mb0200|M.bovis_AF2122/97            TPDEVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTN
Rv0194|M.tuberculosis_H37Rv         TPDEVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTN
MMAR_5223|M.marinum_M               TPEQLWGRCSRYRELLSPATDPLRSLAFEDGVPEPESEP-----EAIDVA
Mflv_1748|M.gilvum_PYR-GCK          -----------------SAD-----LPIDETVPRQREAR-----------
Mvan_5005|M.vanbaalenii_PYR-1       -----------------HTD-----LPIDETVPRRREAR-----------
MSMEG_5659|M.smegmatis_MC2_155      -----------------EQDPNNDNLPIDESIPLRREAR-----------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MLBr_01113|M.leprae_Br4923          ------------DLLFNGVIGRQLPKGISKTQAVAAARTRGDNALADLLS
MUL_4011|M.ulcerans_Agy99           ------------DLLFNGVIGRQLPAGITKAQAIAGARARGDNTFAELLS
MAV_1420|M.avium_104                ------------DLLFNGVVGRQLPAGISKAQAVAAARSRGQNTFADLLS
MAB_1414c|M.abscessus_ATCC_199      ------------DLLFNGVIGRQLPAGQSREQAVETARARGDGQFAQMLS
Mb0200|M.bovis_AF2122/97            VHNPGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRH
Rv0194|M.tuberculosis_H37Rv         VHNPGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRH
MMAR_5223|M.marinum_M               ADATGPSDHSPKPDLLRRLLHDFRGPLIVSLLLVALETGAGLLPPLLIRH
Mflv_1748|M.gilvum_PYR-GCK          -------------ALLGSLLRPYRWAVVLLAVVVVVENAARLSVPILVQK
Mvan_5005|M.vanbaalenii_PYR-1       -------------SLLYLLLRPYRWVVLALAVVVVVENAARLSVPLLVQK
MSMEG_5659|M.smegmatis_MC2_155      -------------SLLISLLRPYRWIVAVLALVVIVENAARLSVPVLVQR
TH_3634|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MLBr_01113|M.leprae_Br4923          GMNLVPG---QGVDFVAVGRTLGLALSLYLVYTLLTWAQARLLNVTVQRI
MUL_4011|M.ulcerans_Agy99           GMKVTPG---QGVDFGAVVRTLALALALYLIASLLIWGQARLLNVTVQRT
MAV_1420|M.avium_104                GMNVVPG---RGVDFGAVARTLALALLLYLVSALLIWVQARLLNRTVQRT
MAB_1414c|M.abscessus_ATCC_199      GMNVIPG---QGVDFHAIGMTLALALSLYLIAGMLAWVQARLLNVTVQRT
Mb0200|M.bovis_AF2122/97            GIDVGIR----RHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQV
Rv0194|M.tuberculosis_H37Rv         GIDVGIR----RHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQV
MMAR_5223|M.marinum_M               GIDVGIR----QHVLTALWWAALAGAAIVAIRLVAQWGSAVVAGTAGEKA
Mflv_1748|M.gilvum_PYR-GCK          GIDDGIPPLLEGGPAITLMTIVATLCGVVVVQAVGRMYFLRRSGRIGQKV
Mvan_5005|M.vanbaalenii_PYR-1       GIDDGIPPLLAGERATTLLTIVAALCGVVVVQACSRMYFLRRSGRIGQKV
MSMEG_5659|M.smegmatis_MC2_155      GIDHGIPPILAGGPARELMVIVATLCAVVLVQATSRMFFLRRSGRVGQKV
TH_3634|M.thermoresistible__bu      ------------------------------------MYFLRRSGRIGQEV
                                                                               .   :. 

MLBr_01113|M.leprae_Br4923          MFALRSDVEDKVHRLPLSYCDTRQRGELLSRVTNDIDNLQSSLSITLSQL
MUL_4011|M.ulcerans_Agy99           VAALRADVEHKLHRLPLSYFDGRQRGELLSRVTNDIDNIQSSLSMTISQL
MAV_1420|M.avium_104                MVALRSAVEDKVHRLPLAYFDGRQRGELLSRVTNDIDNIQSSLSMTISQL
MAB_1414c|M.abscessus_ATCC_199      VVALRTEVENKIHRLPLSYFDSRQRGEILSRVTNDVDNIQTSLQMSINQL
Mb0200|M.bovis_AF2122/97            LFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVA
Rv0194|M.tuberculosis_H37Rv         LFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVA
MMAR_5223|M.marinum_M               LFRLRSLVFAHAQRLDLDAFEDNGDSQIITAVTADVDAIVAFLRTGLVIA
Mflv_1748|M.gilvum_PYR-GCK          LLELRRRVFRHFGRLDIAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL
Mvan_5005|M.vanbaalenii_PYR-1       LLELRRRVFRHFGRLDIAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL
MSMEG_5659|M.smegmatis_MC2_155      LLELRRRVFRHFQRLDLAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL
TH_3634|M.thermoresistible__bu      LLELRRRLFRHFQRLDVAFHERYTSGRVVSRSTNDVEAIQDMLETGFDSL
                                    :  **  :  :  ** :   :    ..:::  * *:: :   *   :   

MLBr_01113|M.leprae_Br4923          LTSLLTVVAVLVVMVSVSPLLALVALLTVPMSLLATRAIAQRSQQLFVAQ
MUL_4011|M.ulcerans_Agy99           VTAILTVVAVLSMMVWISPLLALITLLTVPLSLLVTRAITRRSQRLFVAH
MAV_1420|M.avium_104                LTSVLTVLTVLAMMLSISPLLAGITLLTVPLSLLATRVIVRRSQRLFVAQ
MAB_1414c|M.abscessus_ATCC_199      LSSMLTLVAVLAMMLSISPLLAVITLATVPLSLWVTRTIARRSQRLFVAQ
Mb0200|M.bovis_AF2122/97            VISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRA
Rv0194|M.tuberculosis_H37Rv         VISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRA
MMAR_5223|M.marinum_M               IVSLVTAVGILAALLAINAKLALLIFATLPMLGLATWQFRRASSWTYRQA
Mflv_1748|M.gilvum_PYR-GCK          ITAVLTMVGTAVLLVVLDVKLGLMCLVAFPVLVLLVWWFQRESSKTYREV
Mvan_5005|M.vanbaalenii_PYR-1       ITAVLTLVGTAVLLVVLDVKLGLMCLAAFPILVLLVMWFRRESSKTYREV
MSMEG_5659|M.smegmatis_MC2_155      ITAVLTLFGTAVLLVVLDWRLGLMCLAAFPILVALVWWFRNESARTYRKV
TH_3634|M.thermoresistible__bu      ITAVLTLGGTAILLVTLDVRLGLMCLGAFPVLIALVWWFREESAKTYRKV
                                    : :::*       :: :   *  : : :.*:    .  : . *   :   

MLBr_01113|M.leprae_Br4923          WTSAGRLNAHIEETYSGLTVVKTFGHQTAAREQFRNVNNDVYQASFSAQF
MUL_4011|M.ulcerans_Agy99           WTSTGRLNAHIEETYSGFTVVKTFGHQAAAREQFHNLNDDVYQASFGAQL
MAV_1420|M.avium_104                WTSVGRLNAHIEETYSGFTVVQTFGHRAAARDRFRALNDEVYRASFGAQF
MAB_1414c|M.abscessus_ATCC_199      WANTGKLNAHIEETYSGFTIVKTYGHRAEAEAIFADRNAEVYRSAFGAQF
Mb0200|M.bovis_AF2122/97            RHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQR
Rv0194|M.tuberculosis_H37Rv         RHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQR
MMAR_5223|M.marinum_M               RQRLGTVTATLREYSAGLRIAQAYRAEYVGFQTYFAHSDDYRRLRVRGQR
Mflv_1748|M.gilvum_PYR-GCK          REISALVIVQFVETMTGIKAVQAYRREPRNQQIFEDVADRYREINERTFK
Mvan_5005|M.vanbaalenii_PYR-1       REISALVIVQFVETMTGIKAVQAYRREPRNQQIFEDIADRYRVINEKTFK
MSMEG_5659|M.smegmatis_MC2_155      RESAALVIVQFVETMTGIKAVQAYRREPRNQEIFSDIADDYREINEKTFK
TH_3634|M.thermoresistible__bu      RESAALVIVQFVETMTGIKAVQAYRREPRNQEIFEQVADDYREINEKTLR
                                        . : . : *  :*:  .:::  .      :                

MLBr_01113|M.leprae_Br4923          FSGLVSPATMFISNLGYVVVAALGGLQVATGHITLGNIQAFIQYVRQFNM
MUL_4011|M.ulcerans_Agy99           LSALVQPATTFIGNLGYVAVAVMGGLQVATGQITLGSVQAFIQYVRQFNT
MAV_1420|M.avium_104                FSGLVAPATAVIGNLGYAAVAVLGGLQVATGQITLGNIQAFIQYVRQFNS
MAB_1414c|M.abscessus_ATCC_199      FSGLVSPATAFVGNLSYVAVAVVGGLKVASGGLTLGSIQAFSQYVRQFNQ
Mb0200|M.bovis_AF2122/97            LLALYYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYT
Rv0194|M.tuberculosis_H37Rv         LLALYYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYT
MMAR_5223|M.marinum_M               LLALYFPLVPLTCSLATTLVLFEGGRDVQAGVLSVGALVTYLLYVEMLFA
Mflv_1748|M.gilvum_PYR-GCK          LLAVFMPGVKLVGNLTTGVVLLYGGYRALHGEMTIGTLTAFLLYLRMFFE
Mvan_5005|M.vanbaalenii_PYR-1       LLAVFMPGVKLVGNLTTGVVLLYGGYRVLHGEMTIGTLAAFLLYLRMFFE
MSMEG_5659|M.smegmatis_MC2_155      LLAIFMPGVKLVGNITTGVVLIYGGYRVLNDQMTIGTLAAFLLYLRMFFE
TH_3634|M.thermoresistible__bu      LLAIFMPGVRLVGNITTGVVLLYGGYLVLNDQMTIGTLTAFLLYLRMFFE
                                    : .:  * . .  .:    *   *.  .  . :::* : ::  *:. :  

MLBr_01113|M.leprae_Br4923          PLSQVAGIYNTLQSGLASAERVFDLLDEPEELPDPMLALPPPH----GQV
MUL_4011|M.ulcerans_Agy99           PVSQVAAMYNSLQSGVASAERVFELLDEPEEAADPASALQPPVS-RTGRA
MAV_1420|M.avium_104                PLSQLAGMYNTLQSGVASAERVFALLDEPEEPPDAPPEEKPTAPGPAGRD
MAB_1414c|M.abscessus_ATCC_199      PLTQVAAMYNTLQSGLASAERVFELLDADEETPDPLAAATAPTG------
Mb0200|M.bovis_AF2122/97            PIGELAQMFDDYQRAAVAAGRIRSLLSTRTPSSPAA---RPVG-------
Rv0194|M.tuberculosis_H37Rv         PIGELAQMFDDYQRAAVAAGRIRSLLSTRTPSSPAA---RPVG-------
MMAR_5223|M.marinum_M               PVDKLSQMFDEYQRAAVAVGRIRSLLNTPTAFSPSA---APVG-------
Mflv_1748|M.gilvum_PYR-GCK          PMQEISQFFNTFQSASSALEKLAGVLAEKPGISDPA---KPVR------V
Mvan_5005|M.vanbaalenii_PYR-1       PMQEISQFFNTFQSAASALEKLAGVLAEKPGISDPP---HPVA------L
MSMEG_5659|M.smegmatis_MC2_155      PMQEISQFFNTFQSASSALEKLAGVLAQRPGIADPE---RPVA------L
TH_3634|M.thermoresistible__bu      PMQEISQFFNTFQSAASALEKLAGVLAEEPAIKDPQ---HPVSP-----A
                                    *: ::: :::  * .  :  ::  :*        .     .         

MLBr_01113|M.leprae_Br4923          PRINGRVEFQQVSFAYRT-GTPVIDDLSMVVEPGSTVAIVGPTGAGKTTL
MUL_4011|M.ulcerans_Agy99           PALTGRVEFERVNFAYHP-GHPVIHDLSLVAEPGSTVAIVGPTGAGKTTL
MAV_1420|M.avium_104                AGGGGRVEFAHVSFAYRP-GIRVIDDLSLVAEPGSTVAIVGPTGAGKTTL
MAB_1414c|M.abscessus_ATCC_199      ---SVRVEFEDISFGYSP-GQPVIEGLSLRVEPGQTVAIVGPTGAGKTTL
Mb0200|M.bovis_AF2122/97            -TLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGSGKSTL
Rv0194|M.tuberculosis_H37Rv         -TLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGSGKSTL
MMAR_5223|M.marinum_M               -TLRGEIEFDAVHFRYPTRDAPALAGINLRIPAGQTVVFVGSTGSGKSTL
Mflv_1748|M.gilvum_PYR-GCK          DEVRGEVALLDVHFAYVP-GRPVLPGLDLVIPAGQTVALVGTTGAGKTTI
Mvan_5005|M.vanbaalenii_PYR-1       GEVRGEIALRDLTFEYVP-GRPVLPGLDLVIPAGQTVALVGTTGAGKTTI
MSMEG_5659|M.smegmatis_MC2_155      HAVAGTITFDHVHFAYAP-GRPVLPDLTLTVPAGQTVALVGTTGAGKTTI
TH_3634|M.thermoresistible__bu      RPVRGEIAFHGVQFAYVP-GRPVIPELTLTVPAGQTVALVGTTGAGKTTI
                                          : :  : : * .    .:  : :   .*.**.:**.**:**:*:

MLBr_01113|M.leprae_Br4923          VNLLMRFYDVDSGQILIDGVDITTVSRHALRSRIGMVLQDAWLFDGTIAE
MUL_4011|M.ulcerans_Agy99           VNLLMRFYEVDSGRILVDGIDITTVSRQSLRSHIGMVLQDTWLFDGTISE
MAV_1420|M.avium_104                VNLLMRFYDVDAGRISIDGVDIATMDRRALRSRIGMVLQDTWLFDGTIAE
MAB_1414c|M.abscessus_ATCC_199      VNLLMRFYEVDSGRILLDGIDVSTMTRHDLRSRMGMVLQDTWLFGGTIVE
Mb0200|M.bovis_AF2122/97            IKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRD
Rv0194|M.tuberculosis_H37Rv         IKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRD
MMAR_5223|M.marinum_M               MKLVSRFYDPTDGIIRVDGCDLREFDIDGYRSRLSIVAQEPYLFAGTVRD
Mflv_1748|M.gilvum_PYR-GCK          AKLITRFYDPGSGTVSLDGVDLRDMSQADLRRHVVMVTQENFMFGGTIAD
Mvan_5005|M.vanbaalenii_PYR-1       AKLITRFYDPVAGTVMLDEIDLRDVAQAELRRHVVMVTQENFMFGGTVAD
MSMEG_5659|M.smegmatis_MC2_155      AKLIARFYDPTSGTVTLDGVDLRDLSQSELRRHVVMVTQENFMFEGTVAD
TH_3634|M.thermoresistible__bu      ATLIARFYDPTAGSVTLDGIDLRDIAQSELRRHVVMVTQENFMFDGTVAD
                                     .*: ***:   * : :*  *:  .     * :: :* *: ::* **: :

MLBr_01113|M.leprae_Br4923          NIAYGRPQASEDEVMEAAKAAYVDRFVHTLSAGYQTRVSGDGDNISAGEK
MUL_4011|M.ulcerans_Agy99           NIAYGRPEASPDDIIQAAKAAYVDRFVHMLPASYQTRISGDGSNISAGEK
MAV_1420|M.avium_104                NIGYGRPGAGDDEIVAAARAAYVDRFVQNLPDGYHTRVSGDGGNLSAGER
MAB_1414c|M.abscessus_ATCC_199      NIAYGRPGASQEEILEAARAAYVDRFVRTLPDGYDTKIADDGGNISAGEK
Mb0200|M.bovis_AF2122/97            AIAYGRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQL
Rv0194|M.tuberculosis_H37Rv         AIAYGRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQL
MMAR_5223|M.marinum_M               AIAYGRPDATDAQVERAAREVGAHPMIAALDGGYQHEVAAGGRNLSAGQL
Mflv_1748|M.gilvum_PYR-GCK          NIRFGRPGATDDEVRAAARAVGAHTFIDVLPDGYDTDVAKRGGRLSAGQR
Mvan_5005|M.vanbaalenii_PYR-1       NIRFGRPDATDDEVRAAARAVGAHTFIGALPDGYDTDVAKRGGRLSAGQR
MSMEG_5659|M.smegmatis_MC2_155      NIRFGRPDATDAQVRAAAEAVGADRFIATLPEGYGTDVAKRGGRLSAGQR
TH_3634|M.thermoresistible__bu      NIRFGRPEATDAEIAAAAEAVGADRFIAALPDGYHTDVAKRGSRLSAGQR
                                     * :*** *   ::  **. . .. ::  *  .*   ::  * .:***: 

MLBr_01113|M.leprae_Br4923          QLITIARAFLARPQLLILDEATSSIDTRTEALIARATHDLLQDRTSFIIA
MUL_4011|M.ulcerans_Agy99           QLITIARAFLARPQLLILDEATSSVDTRTELLIARATAELRRDRTSFIIA
MAV_1420|M.avium_104                QLITIARAFLARPQLLILDEATSSVDTRTEALIAHATRELRRDRTSFIIA
MAB_1414c|M.abscessus_ATCC_199      QLITIARAFLARPQLLILDEATSSVDTRTELRIQRAMAELRRDRTSFIIA
Mb0200|M.bovis_AF2122/97            QLLALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVA
Rv0194|M.tuberculosis_H37Rv         QLLALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVA
MMAR_5223|M.marinum_M               QLLALARARLVDSDILLLDEATVALDPATEALVHWATLGLAADRTTLIIA
Mflv_1748|M.gilvum_PYR-GCK          QLVAFARAFLADPAVLILDEATSSLDIPSERLVQRALETVLADRTAVVIA
Mvan_5005|M.vanbaalenii_PYR-1       QLVAFARAFLADPAVLILDEATSSLDIPSERMVQRALETVLADRTAVVIA
MSMEG_5659|M.smegmatis_MC2_155      QLIAFARAFLADPAVLILDEATSSLDIPSERMVQRALETVLADRTALVIA
TH_3634|M.thermoresistible__bu      QLIAFARAFLADPAVLILDEATSALDIPSERMVQRALRTVLADRTALVIA
                                    **:::*** *. . :*:***** ::*  :*  :  *   :   **:.::*

MLBr_01113|M.leprae_Br4923          HHLPTIRDADHILVVAAGKIVEQGSHAKLLARRGAYYRMTQA--------
MUL_4011|M.ulcerans_Agy99           HRLSTIRDADQILVVQAGQIVEHGTHAELLANRGAYYAMTRA--------
MAV_1420|M.avium_104                HRLSTIRDADRIAVIEAGRIFEQGTHAELLARRGVYYAMTQA--------
MAB_1414c|M.abscessus_ATCC_199      HRLSTIRDADRIVVLDGGRVTESGTHTELLARHGAYFAMTQS--------
Mb0200|M.bovis_AF2122/97            HGLAIAEHADRIVVLEHGTVVEDGAHTELLAAG-GHYSRLWAAHTRLCSP
Rv0194|M.tuberculosis_H37Rv         HGLAIAEHADRIVVLEHGTVVEDGAHTELLAAG-GHYSRLWAAHTRLCSP
MMAR_5223|M.marinum_M               HELAIAEFVDRIVVLEQGTIVEDGTHVELLAAG-GRYAALWAAHSRVGRP
Mflv_1748|M.gilvum_PYR-GCK          HRLSTVQIADRVLVLEHGRIVEDGPPEELTAREGGHYAALHRSWVQSLA-
Mvan_5005|M.vanbaalenii_PYR-1       HRLSTVQIADRVLVLEHGRIVEDGAPDELTARDHGHYAALHRSWVQSLA-
MSMEG_5659|M.smegmatis_MC2_155      HRLSTVQIADRVLVLEHGRIIEDGSPADLIGRTDGAYAALHRAWVDSLA-
TH_3634|M.thermoresistible__bu      HRLSTVEIADRVLVLERGRVVEDGPPGELIRRGEGRYAALHHAWLESLG-
                                    * *.  . .*:: *:  * : * *.  .*       :             

MLBr_01113|M.leprae_Br4923          ----------------------
MUL_4011|M.ulcerans_Agy99           ----------------------
MAV_1420|M.avium_104                ----------------------
MAB_1414c|M.abscessus_ATCC_199      ----------------------
Mb0200|M.bovis_AF2122/97            EITQLQCIDA------------
Rv0194|M.tuberculosis_H37Rv         EITQLQCIDA------------
MMAR_5223|M.marinum_M               SPSDDRPIPTELLVHSPDTDVL
Mflv_1748|M.gilvum_PYR-GCK          ----------------------
Mvan_5005|M.vanbaalenii_PYR-1       ----------------------
MSMEG_5659|M.smegmatis_MC2_155      ----------------------
TH_3634|M.thermoresistible__bu      ----------------------