For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MHHRTRVMILLAALGGLRVAEISRVRGEDIDIAKPAIHVVGKGKRSAWLPLHVLLVDAALTMPTRGWWFP ANSRRPGDHVHSKSVSDIIGNAMRRAGVRGTPHGLRHWYGTTLLDDGADLRTVQELLRHRSLSTTQIYTR VTDERRAAAVGRLNPFRGAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0779 | - | - | 100% (160) | site-specific recombinase, phage integrase family protein |
| M. avium 104 | MAV_3746 | xerC | 8e-16 | 33.73% (166) | site-specific tyrosine recombinase XerC |
| M. avium 104 | MAV_3070 | xerD | 1e-15 | 36.18% (152) | site-specific tyrosine recombinase XerD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2918c | xerC | 8e-17 | 36.26% (171) | site-specific tyrosine recombinase XerC |
| M. gilvum PYR-GCK | Mflv_3500 | xerD | 5e-17 | 37.50% (152) | site-specific tyrosine recombinase XerD |
| M. tuberculosis H37Rv | Rv2894c | xerC | 9e-17 | 36.26% (171) | site-specific tyrosine recombinase XerC |
| M. leprae Br4923 | MLBr_01600 | xerC | 5e-17 | 32.94% (170) | site-specific tyrosine recombinase XerC |
| M. abscessus ATCC 19977 | MAB_3204c | xerC | 1e-16 | 34.34% (166) | site-specific tyrosine recombinase XerC |
| M. marinum M | MMAR_2506 | xerD | 1e-15 | 36.18% (152) | integrase/recombinase, XerD |
| M. smegmatis MC2 155 | MSMEG_2515 | xerC | 6e-17 | 36.81% (163) | site-specific tyrosine recombinase XerC |
| M. thermoresistible (build 8) | TH_2517 | - | 7e-40 | 50.96% (157) | PUTATIVE putative site-specific recombinase, phage integrase |
| M. ulcerans Agy99 | MUL_1690 | xerD | 5e-15 | 35.53% (152) | site-specific tyrosine recombinase XerD |
| M. vanbaalenii PYR-1 | Mvan_2207 | xerC | 5e-17 | 34.15% (164) | site-specific tyrosine recombinase XerC |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2918c|M.bovis_AF2122/97 -------------------MQAILDEFDEYLALQCGRSVHTRRAYLGDLR
Rv2894c|M.tuberculosis_H37Rv -------------------MQAILDEFDEYLALQCGRSVHTRRAYLGDLR
MLBr_01600|M.leprae_Br4923 --------------------MAILDEFDEHLALRCGRSEHTRRAYLGDLR
Mvan_2207|M.vanbaalenii_PYR-1 MVCHGRGVQTGGQERSDPGIGSCLEEFDEYLALERGRSEHTRRAYLGDVR
MAB_3204c|M.abscessus_ATCC_199 ---------------MTPQLAAILDEFAEHLALERGRSVHTQRAYRGDLT
MSMEG_2515|M.smegmatis_MC2_155 -------------------MESVLDQFDAYLGLERGHSDHTRRAYRGDLT
MMAR_2506|M.marinum_M -------------MST-LTLDTQLQGYLDHLAIERGVAANTLSSYRRDLR
MUL_1690|M.ulcerans_Agy99 -------------MST-LTLDTQLQGYLDHLAIERGVAANTLSSYRRDLR
Mflv_3500|M.gilvum_PYR-GCK -------------MGVGAVLDGQLQGYLDHLAIERGVAANTLSSYRRDLR
MAV_0779|M.avium_104 --------------------------------------------------
TH_2517|M.thermoresistible__bu ----------------LESVQYPLVNTWRTWQFAQSLSKRTVDERVATVT
Mb2918c|M.bovis_AF2122/97 SLFAFLADR--GSSLDALT-------LSVLRSWLAATAGAGAARTTLARR
Rv2894c|M.tuberculosis_H37Rv SLFAFLADR--GSSLDALT-------LSVLRSWLAATAGAGAARTTLARR
MLBr_01600|M.leprae_Br4923 SLLTHLEGR--GSRLDQLS-------LPVLRSWLATAAGAGAARTTLARR
Mvan_2207|M.vanbaalenii_PYR-1 ALFDFLAERRPGTGLRGLT-------LPVLRSWLAAQATAGAARSTLARR
MAB_3204c|M.abscessus_ATCC_199 LLFDHLSASNPEATLADLS-------LPVLRSWLGAQARQGAARSTVARR
MSMEG_2515|M.smegmatis_MC2_155 ALFDFVEQRTGERSLARVS-------LPLLRSWLAEQSASGAARTTLARR
MMAR_2506|M.marinum_M RYSKHLEDR-GITDLAKVGEDDVSEFLVALRRGDPESGVLGLSAVSAARA
MUL_1690|M.ulcerans_Agy99 RYSKHLEDR-GITDLAKVGEDDVSEFLVALRRGDPESGVLGLSAVSAARA
Mflv_3500|M.gilvum_PYR-GCK RYAEHLKAR-GVGDLAAVTETDVSEFLVALRLGDPDGGVVPLSAVSAARA
MAV_0779|M.avium_104 --------------------------------------------------
TH_2517|M.thermoresistible__bu RMANWCQTSPESATSEQIA------------EWLAAGDWMPRTRWTYHR-
Mb2918c|M.bovis_AF2122/97 TSAVKAFTAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAA
Rv2894c|M.tuberculosis_H37Rv TSAVKAFTAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAA
MLBr_01600|M.leprae_Br4923 ISAVKAFTAWAKWRGQLAADPAARLQVPRAYRTLPAVLRQDQALQIMAAA
Mvan_2207|M.vanbaalenii_PYR-1 TSAVKTFTAWAVRRGLMTEDPAARLQVPKARRTLPSVLRQDQAREAMDAA
MAB_3204c|M.abscessus_ATCC_199 TSAVKIFTAWATRRGLLPTDPAIRLQQPKSRRTLPAVLRQDQAAAAMEAA
MSMEG_2515|M.smegmatis_MC2_155 TSSVKTFCAWALRRGLIGVDPAARLQVPKARRTLPAVLRRDQALDALDAV
MMAR_2506|M.marinum_M LIAVRGLHRFAAAEGLAALDVARAVRPPTPGRRLPKSLTIDEVLALLEGA
MUL_1690|M.ulcerans_Agy99 LIAVRGLHRFAAAEGLAALDVARAVRPPTPGRRLPKSLTIDEVLALLEGA
Mflv_3500|M.gilvum_PYR-GCK LIAVRGLHRFAAAEGIAAIDVARDVKPPTPSRRLPKSLSIDEVLALLEAA
MAV_0779|M.avium_104 --------------------------------------------------
TH_2517|M.thermoresistible__bu --ALSAWFTWLQLQGHRLDNPMLRLGDPKRPKSVPRPLSNADVARLLTTR
Mb2918c|M.bovis_AF2122/97 ESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLG
Rv2894c|M.tuberculosis_H37Rv ESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLG
MLBr_01600|M.leprae_Br4923 KSGAEQGDPLALRDRLIVEMLYATGIRVSELCGLDIDDVDTRHRLVRVLG
Mvan_2207|M.vanbaalenii_PYR-1 KSGAQQGDPLALRDRLIVEMLYATGIRVSELCGLDIDDVDTARRLLRVLG
MAB_3204c|M.abscessus_ATCC_199 HSGAEQDDPMALRDRLIVEMLYATGIRVSELCGLDIDDIDRPRKVLRVLG
MSMEG_2515|M.smegmatis_MC2_155 NSGAQEGDPIALRDRLIVELLYATGIRVSELCGLDIDDIDTSRRVVRVLG
MMAR_2506|M.marinum_M GGDNPADGPLTLRNRALLELLYSTGSRISEAVGLDVDDIDTQARTVLLQG
MUL_1690|M.ulcerans_Agy99 GGDNPADGPLTLRNRALLELLYSTGSRISEAVGLDVDDIDTQARTVLLQG
Mflv_3500|M.gilvum_PYR-GCK GGDSEADSPLTLRNRALLELLYSTGARISEAVGLDIDDVDTSARSVLLRG
MAV_0779|M.avium_104 ---------MHHRTRVMILLAALGGLRVAEISRVRGEDIDIAKPAIHVVG
TH_2517|M.thermoresistible__bu ---------MHTRTRAMVLLATFEGLRTFEIAKVRGEHFDLVSRTMTVTG
: * * :: : * * * : :..* : : *
Mb2918c|M.bovis_AF2122/97 KGNKQRTVPFGQPAADALHAWLVDGRRALVTAESG-HALLLGARGRRLDV
Rv2894c|M.tuberculosis_H37Rv KGNKQRTVPFGQPAADALHAWLVDGRRALVTAESG-HALLLGARGRRLDV
MLBr_01600|M.leprae_Br4923 KGNKQRTAPFGVPAADALRGWLDDGRPALVTVESG-PALLLGSRGRRLDV
Mvan_2207|M.vanbaalenii_PYR-1 KGNKQRTVPYGDPAHAALTAWLSDGRPALVTAGSG-AALLLGARGGRLDP
MAB_3204c|M.abscessus_ATCC_199 KGDKERTVPFGDPAADALSAWLDRGRPHLAVPASG-AALLLGARGRRVDP
MSMEG_2515|M.smegmatis_MC2_155 KGNKQRTVPFGEPAHAALTAWLTEGRPQLSIPESG-PALLLGARGRRLDP
MMAR_2506|M.marinum_M KGGKQRLVPVGRPAVQALDAYLVRGRPELARRGRGTPAIFLNARGGRLSR
MUL_1690|M.ulcerans_Agy99 KGGKQRLVPVGRPAVQALDAYLVRGRPELARRGRGTPAIFLNARGGRLSR
Mflv_3500|M.gilvum_PYR-GCK KGGKQRLIPIGRPAVTALETYLVRGRPDLARRGRGTPAIFLNARGGRLSR
MAV_0779|M.avium_104 KGKRSAWLPLHVLLVDAALTMPTRGWWFPAN---------SRRPGDHVHS
TH_2517|M.thermoresistible__bu KGGITATLPLHHRVVEHAYRMPRKGYWFPG------------RNGGHQRR
** * * * :
Mb2918c|M.bovis_AF2122/97 RQARTAVHQTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHS
Rv2894c|M.tuberculosis_H37Rv RQARTAVHQTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHS
MLBr_01600|M.leprae_Br4923 RQARTVVHQTVAVVAGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHS
Mvan_2207|M.vanbaalenii_PYR-1 RQARTVVHQTMAAVSGAPDIGPHGLRHSAATHLLEGGADLRVVQELLGHS
MAB_3204c|M.abscessus_ATCC_199 RQVRTVVHQTMSAVPGAPDIGPHGLRHSAATHLLEGGADLRVVQELLGHS
MSMEG_2515|M.smegmatis_MC2_155 RQARTVVHQTVSAVNGAPDIGPHGLRHSAATHLLEGGADLRIVQELLGHT
MMAR_2506|M.marinum_M QSAWQVLQDAAERAGITSGVSPHMLRHSFATHLLEGGADVRVVQELLGHA
MUL_1690|M.ulcerans_Agy99 QSAWQVLQDAAERADITSGVSPHMLRHSFATHLLEGGADVRVVQELLGHA
Mflv_3500|M.gilvum_PYR-GCK QSAWQVLQDAAGRAGVTATVSPHVLRHSFATHLLDGGADVRVVQELLGHA
MAV_0779|M.avium_104 KSVSDIIGNAMRRAGVRG--TPHGLRHWYGTTLLDDGADLRTVQELLRHR
TH_2517|M.thermoresistible__bu ESVGQTIKEAITRAGAVG--SAHQLRHWFGTALVEAGVDLRTVQTLLRHQ
... : :: . .* *** .* *:: *.*:* ** ** *
Mb2918c|M.bovis_AF2122/97 SLATTQLYTHVAVARLRAVHERAHPRA---------------
Rv2894c|M.tuberculosis_H37Rv SLATTQLYTHVAVARLRAVHERAHPRA---------------
MLBr_01600|M.leprae_Br4923 SLATTQLYTHVAVSRLRVVHDQAHPRA---------------
Mvan_2207|M.vanbaalenii_PYR-1 SLATTQLYTHVTVARLRAVHDQAHPRA---------------
MAB_3204c|M.abscessus_ATCC_199 TLATTQLYTHVTVARLRAVHDQAHPRA---------------
MSMEG_2515|M.smegmatis_MC2_155 SLATTQLYTHVTVERLRAVHDQAHPRA---------------
MMAR_2506|M.marinum_M SVTTTQIYTLVTVHALREVWAGAHPRAT--------------
MUL_1690|M.ulcerans_Agy99 SVTTTQIYTLVTVHALREVWAGAHPRAT--------------
Mflv_3500|M.gilvum_PYR-GCK SVTTTQIYTMVTVNALREVWAGAHPRAR--------------
MAV_0779|M.avium_104 SLSTTQIYTRVTDERRAAAVGRLNPFR------GAS------
TH_2517|M.thermoresistible__bu NLSSTEIYTQVKEPRRADAIQLLDPFQLDMVALSASPWKEAA
.:::*::** * . .*