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M. thermoresistible (build 8) TH_2296 (-)

annotation: cytidine/deoxycytidylate deaminase, zinc-binding region
coordinates: 4503161 - 4503640
length: 160

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2296--100% (160)cytidine/deoxycytidylate deaminase, zinc-binding region
M. thermoresistible (build 8)TH_1653-1e-0533.67% (98) POSSIBLE CYTIDINE/DEOXYCYTIDYLATE DEAMINASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3778c-5e-0635.71% (98) cytidine/deoxycytidylate deaminase
M. gilvum PYR-GCKMflv_3332-2e-6471.52% (158) CMP/dCMP deaminase, zinc-binding
M. tuberculosis H37RvRv3752c-5e-0635.71% (98) cytidine/deoxycytidylate deaminase
M. leprae Br4923MLBr_02474-2e-0533.67% (98) putative cytidine/deoxycytidylate deaminase
M. abscessus ATCC 19977MAB_3459-4e-5563.58% (151) putative cytidine/deoxycytidylate deaminase
M. marinum MMMAR_4851-2e-0830.53% (95) deaminase
M. avium 104MAV_0777-1e-0834.52% (84) cytidine/deoxycytidylate deaminase
M. smegmatis MC2 155MSMEG_3575-3e-6573.25% (157) cytidine/deoxycytidylate deaminase, zinc-binding region
M. ulcerans Agy99MUL_0449-3e-0832.32% (99) hypothetical protein MUL_0449
M. vanbaalenii PYR-1Mvan_3058-1e-6570.89% (158) CMP/dCMP deaminase, zinc-binding

CLUSTAL 2.0.9 multiple sequence alignment


TH_2296|M.thermoresistible__bu      ----------VAIGDDDLRYLHRCVELARAALAAGDEPFGSILVDADGQI
MSMEG_3575|M.smegmatis_MC2_155      ----------MAISDADLKYLRRCVDLAREALDDGDEPFGSVLVDHTGTT
Mflv_3332|M.gilvum_PYR-GCK          ----MRRLRPMAVTGDDLRHLRRCVELAREAQDAGDEPFGSLLLDADGVT
Mvan_3058|M.vanbaalenii_PYR-1       ----------MAVTDDDLVFLRRCVSLARTALDGGDEPFGSLLVDHEGSV
MAB_3459|M.abscessus_ATCC_1997      ------------MDDNDIQHLRRCVELATEALDAGDEPFGSLLTGPDGAV
Mb3778c|M.bovis_AF2122/97           -------------MTTDEDLIRAALAVAATAGPRDVPVGAVVVGADGTEL
Rv3752c|M.tuberculosis_H37Rv        -------------MTTDEDLIRAALAVAATAGPRDVPVGAVVVGADGTEL
MLBr_02474|M.leprae_Br4923          MPSAAGRRHQTRSVTTDEDLIRAALTVATTAGSRDVPIGAVVLGADGNEL
MMAR_4851|M.marinum_M               ----------------MTDFAQRAIDLARQNVAEGGRPFATVIVKDGQVL
MUL_0449|M.ulcerans_Agy99           ----------------MTDFAQRAIDFARLNVAEGGRPFATVIVKDGQVL
MAV_0777|M.avium_104                ----------------MTDFARRTIDLARQNVAEGGRPFATVIVQDGEVL
                                                         :  : .*      .    . ::       

TH_2296|M.thermoresistible__bu      RYEDRNRVSGGDRTRHPEFAIARWAAQHLGPDERGR-ATVYTSGEHCPMC
MSMEG_3575|M.smegmatis_MC2_155      LFEDRNRVKDGDATAHPEFAIARWAARHLTPDRRAR-ATVYTSGEHCPMC
Mflv_3332|M.gilvum_PYR-GCK          RVEDRNRVKDGDATRHPEYAIAKWAVENLSPD--DR-ATVYTSGEHCPMC
Mvan_3058|M.vanbaalenii_PYR-1       RFEDHNRVKDGDATRHPEFAIARWAVEHLSPAQRNR-STVYTSGEHCPMC
MAB_3459|M.abscessus_ATCC_1997      LAEDRNRVGAGDPTRHPEFELARWSVRNLSPTDRAL-STVYTSGEHCPMC
Mb3778c|M.bovis_AF2122/97           ARAVNAREALGDPTAHAEILAMRLAAGVLGDGWRLEGTTLAVTVEPCTMC
Rv3752c|M.tuberculosis_H37Rv        ARAVNAREALGDPTAHAEILAMRLAAGVLGDGWRLEGTTLAVTVEPCTMC
MLBr_02474|M.leprae_Br4923          ARAVNAREAIGDPTAHAEILAMRAAAGTLGNGWRLEGTTLAVTVEPCTMC
MMAR_4851|M.marinum_M               AESANKVAQTNDPTAHAEILAIRAACTKLGT-EQLFGTTFYVLAHPCPMC
MUL_0449|M.ulcerans_Agy99           AESANKVAQTNDPTAHAEILAIRAACTKLGT-EQLFGTTFYVLAHPCPMC
MAV_0777|M.avium_104                AESANKAAQTNDPTAHAEILAIRAACLKLGT-EHLVDATIYVLAHPCPMC
                                        .     .* * *.*    : :   *        :*. .  . *.**

TH_2296|M.thermoresistible__bu      AAAHAWVGLGRIVYA----------ASAAQLSGWLAEWGAPPGPVAPLPV
MSMEG_3575|M.smegmatis_MC2_155      AAAHAWVGLGRIVYA----------TSSAQLGGWLTEWGAQAPPVATLPI
Mflv_3332|M.gilvum_PYR-GCK          AAAHAWVGLGRVVYA----------ASSVQLAQWLVEWKAPPPPVASLPI
Mvan_3058|M.vanbaalenii_PYR-1       AAAHAWVGLGRVVYA----------ASSAQLAQWLREWGVPAPPVATLPI
MAB_3459|M.abscessus_ATCC_1997      SAAHAWVGLGRIVYA----------SSSAQLTQWLTELGAPPSPVASLSI
Mb3778c|M.bovis_AF2122/97           AGALVLARVARLVFG----------AWEPKTGAVGSLWDVVRDRRLNHRP
Rv3752c|M.tuberculosis_H37Rv        AGALVLARVARLVFG----------AWEPKTGAVGSLWDVVRDRRLNHRP
MLBr_02474|M.leprae_Br4923          AGALVLARIERLVFG----------AWQPKTGAVGSLWDVVRDHRLNHRP
MMAR_4851|M.marinum_M               LGSLYYCSPDEVIFLTTRDIYEQYYVDDRKYFELATFYDEFAKAWQDRRL
MUL_0449|M.ulcerans_Agy99           LGS-----------------------------------------------
MAV_0777|M.avium_104                LGALYYCSPREVIFLTTRESYEPYYVDDRKYFELSNFYAEFAKPFDERRL
                                     .:                                               

TH_2296|M.thermoresistible__bu      TVVAPGLVADGPAAELTETMRELYERKFRP---
MSMEG_3575|M.smegmatis_MC2_155      NTVAPGVVVDGPAEELAETMHNLYRAKFGR---
Mflv_3332|M.gilvum_PYR-GCK          TTVAPGVPVDGPAPELTEEMKTLYERAFRR---
Mvan_3058|M.vanbaalenii_PYR-1       ATVAPGVDVDGPAAELTEEMKALYARAFRA---
MAB_3459|M.abscessus_ATCC_1997      NEVAPGVQTDGPAPDLAEDVRALHVRFLGDA--
Mb3778c|M.bovis_AF2122/97           EVRGG--VLARECAAPLEAFFARQRLG------
Rv3752c|M.tuberculosis_H37Rv        EVRGG--VLARECAAPLEAFFARQRLG------
MLBr_02474|M.leprae_Br4923          AVRGG--VLAQECTAPLEAFFAHQRLSKGPPVR
MMAR_4851|M.marinum_M               PMRYDPRPSAVNVYRFWQELNGGKRAAAPDAAG
MUL_0449|M.ulcerans_Agy99           -----------------QELNGGKRAAAPNSAD
MAV_0777|M.avium_104                PMRYQPHPDAVDVYRLWNERNGGRRRSTVVPSD
                                                     :