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M. bovis AF2122 / 97 Mb3778c (-)

annotation: cytidine/deoxycytidylate deaminase
coordinates: 4135541 - 4135999
length: 152

VTTDEDLIRAALAVAATAGPRDVPVGAVVVGADGTELARAVNAREALGDPTAHAEILAMRLAAGVLGDGW
RLEGTTLAVTVEPCTMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGGVLARECAA
PLEAFFARQRLG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3778c--100% (152)cytidine/deoxycytidylate deaminase
M. bovis AF2122 / 97Mb1444ribG1e-0935.29% (136) bifunctional diaminohydroxyphosphoribosylaminopyrimidine
M. bovis AF2122 / 97Mb0851c-2e-0838.46% (104) deaminase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1214-8e-6985.14% (148) CMP/dCMP deaminase, zinc-binding
M. tuberculosis H37RvRv3752c-1e-83100.00% (152) cytidine/deoxycytidylate deaminase
M. leprae Br4923MLBr_02474-1e-7488.08% (151) putative cytidine/deoxycytidylate deaminase
M. abscessus ATCC 19977MAB_0268-2e-6379.59% (147) cytidine/deoxycytidylate deaminase family protein
M. marinum MMMAR_5295-8e-7689.47% (152) cytidine/deoxycytidylate deaminase
M. avium 104MAV_0324-6e-7791.45% (152) cytidine and deoxycytidylate deaminase family protein
M. smegmatis MC2 155MSMEG_6327-1e-6785.14% (148) cytidine and deoxycytidylate deaminase family protein
M. thermoresistible (build 8)TH_1653-3e-7187.16% (148) POSSIBLE CYTIDINE/DEOXYCYTIDYLATE DEAMINASE
M. ulcerans Agy99MUL_4370-1e-7588.82% (152) cytidine/deoxycytidylate deaminase
M. vanbaalenii PYR-1Mvan_5594-9e-6782.43% (148) CMP/dCMP deaminase, zinc-binding

CLUSTAL 2.0.9 multiple sequence alignment


Mb3778c|M.bovis_AF2122/97           ----------------MTTDEDLIRAALAVAATAGPRDVPVGAVVVGADG
Rv3752c|M.tuberculosis_H37Rv        ----------------MTTDEDLIRAALAVAATAGPRDVPVGAVVVGADG
Mflv_1214|M.gilvum_PYR-GCK          -----------------MTDEDLIRAALDAARGAGPRDVPIGAVVFDAEG
Mvan_5594|M.vanbaalenii_PYR-1       MNRQFSSAGEPAIQSKQVTDEELIRAALDAARLAGPRDVPIGAVVFAPDG
MAB_0268|M.abscessus_ATCC_1997      --------------MTFPDDEALIRAALVAAREAGSQDVPIGAVIYAADG
TH_1653|M.thermoresistible__bu      -------------MIGSVTDEDMIRAALTAAREAGPRDVPIGAVVFGPDG
MSMEG_6327|M.smegmatis_MC2_155      -----------------MTPESQIRAALEAARTAGPRDVPIGAVVYAADG
MMAR_5295|M.marinum_M               ----------------MIADEDLVRAALAAAATAGPRDVPIGAVVISADG
MUL_4370|M.ulcerans_Agy99           ----------------MIADEDLVRAALAAAATAGPRDVPIGAVMISADG
MAV_0324|M.avium_104                ----------------MISDEDLIRSALAVAATAGPRDVPIGAVVVGADG
MLBr_02474|M.leprae_Br4923          ---MPSAAGRRHQTRSVTTDEDLIRAALTVATTAGSRDVPIGAVVLGADG
                                                        *  :*:** .*  **.:***:***:  .:*

Mb3778c|M.bovis_AF2122/97           TELARAVNAREALGDPTAHAEILAMRLAAGVLGDGWRLEGTTLAVTVEPC
Rv3752c|M.tuberculosis_H37Rv        TELARAVNAREALGDPTAHAEILAMRLAAGVLGDGWRLEGTTLAVTVEPC
Mflv_1214|M.gilvum_PYR-GCK          TELARAANAREELGDPTAHAEILALRAAALVHGDGWRLEGATLAVTVEPC
Mvan_5594|M.vanbaalenii_PYR-1       RELARAANAREEFGDPTAHAEILALRAAARELGDGWRLEGATLAVTVEPC
MAB_0268|M.abscessus_ATCC_1997      TELARAANARERLGDPTAHAEVLALRAAAAKHGDGWRLEGATLAVTVEPC
TH_1653|M.thermoresistible__bu      GELARAANAREQLGDPTAHAEVLALRAAARRLGDGWRLEGATLAVTVEPC
MSMEG_6327|M.smegmatis_MC2_155      TELARAVNVREAYGDPAGHAEIVAMRAAAKVLGDGWRLEGATLAVTVEPC
MMAR_5295|M.marinum_M               TELARAVNAREELGDPTAHAEILALRAAARVLGDGWRLEGATLAVTVEPC
MUL_4370|M.ulcerans_Agy99           TELARAVNAREELGDPTAHAEILALRAAARVLGDGWRLEGATLAVTVEPC
MAV_0324|M.avium_104                TELARAVNAREALGDPTAHAEILALRAAAAALGDGWRLEGATLAVTVEPC
MLBr_02474|M.leprae_Br4923          NELARAVNAREAIGDPTAHAEILAMRAAAGTLGNGWRLEGTTLAVTVEPC
                                     *****.*.**  ***:.***::*:* **   *:******:*********

Mb3778c|M.bovis_AF2122/97           TMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGGVL
Rv3752c|M.tuberculosis_H37Rv        TMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGGVL
Mflv_1214|M.gilvum_PYR-GCK          TMCAGALVMARVARVVFGAWEPKTGAVGSLWDVVRDRRLTHRPQVRGGVL
Mvan_5594|M.vanbaalenii_PYR-1       TMCAGALVMARVARVVFGAWEPKTGAVGSLWDVVRDRRLTHRPQVRGGVL
MAB_0268|M.abscessus_ATCC_1997      TMCAGALVLARVGRVVFGAWEPKTGAVGSLWDVVRDRRQAHRPEVRGGVL
TH_1653|M.thermoresistible__bu      TMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGGVL
MSMEG_6327|M.smegmatis_MC2_155      TMCAGALVLARVSRLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVIGGVL
MMAR_5295|M.marinum_M               TMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPQVRGGVL
MUL_4370|M.ulcerans_Agy99           TMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPQVRGGVL
MAV_0324|M.avium_104                TMCAGALVLARIARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGGVL
MLBr_02474|M.leprae_Br4923          TMCAGALVLARIERLVFGAWQPKTGAVGSLWDVVRDHRLNHRPAVRGGVL
                                    ********:**: *:*****:***************:*  *** * ****

Mb3778c|M.bovis_AF2122/97           ARECAAPLEAFFARQRLG-------
Rv3752c|M.tuberculosis_H37Rv        ARECAAPLEAFFARQRLG-------
Mflv_1214|M.gilvum_PYR-GCK          EAECAAPLEEFFARQR---------
Mvan_5594|M.vanbaalenii_PYR-1       EAECAAPLEEFFAGQR---------
MAB_0268|M.abscessus_ATCC_1997      EHECAALLERFFAAKR---------
TH_1653|M.thermoresistible__bu      AAECAAPLEEFFARQRDPDSPRGLG
MSMEG_6327|M.smegmatis_MC2_155      ADECAALLEEFFARQR---------
MMAR_5295|M.marinum_M               AQECAAPLEEFFGRQRLG-------
MUL_4370|M.ulcerans_Agy99           AQECAAPLEEFFGRQRLG-------
MAV_0324|M.avium_104                ERECAALLEGFFARQRLG-------
MLBr_02474|M.leprae_Br4923          AQECTAPLEAFFAHQRLSKGPPVR-
                                      **:* ** **. :*