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M. avium 104 MAV_0777 (-)

annotation: cytidine/deoxycytidylate deaminase
coordinates: 744881 - 745381
length: 166

TDFARRTIDLARQNVAEGGRPFATVIVQDGEVLAESANKAAQTNDPTAHAEILAIRAACLKLGTEHLVDA
TIYVLAHPCPMCLGALYYCSPREVIFLTTRESYEPYYVDDRKYFELSNFYAEFAKPFDERRLPMRYQPHP
DAVDVYRLWNERNGGRRRSTVVPSD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_0777--100% (166)cytidine/deoxycytidylate deaminase
M. avium 104MAV_0324-1e-1045.33% (75) cytidine and deoxycytidylate deaminase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0851c-3e-4767.19% (128) deaminase
M. gilvum PYR-GCKMflv_1214-2e-1141.67% (96) CMP/dCMP deaminase, zinc-binding
M. tuberculosis H37RvRv0828c-3e-4767.19% (128) deaminase
M. leprae Br4923MLBr_02474-2e-1044.00% (75) putative cytidine/deoxycytidylate deaminase
M. abscessus ATCC 19977MAB_0053c-9e-7274.85% (163) cytidine/deoxycytidylate deaminase
M. marinum MMMAR_4851-8e-7380.38% (158) deaminase
M. smegmatis MC2 155MSMEG_3575-1e-0932.65% (98) cytidine/deoxycytidylate deaminase, zinc-binding region
M. thermoresistible (build 8)TH_1653-7e-1240.62% (96) POSSIBLE CYTIDINE/DEOXYCYTIDYLATE DEAMINASE
M. ulcerans Agy99MUL_0449-3e-3783.72% (86) hypothetical protein MUL_0449
M. vanbaalenii PYR-1Mvan_5594-4e-1241.67% (96) CMP/dCMP deaminase, zinc-binding

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1214|M.gilvum_PYR-GCK          -----------------MTDEDLIRAALDAARGAGPRDVPIGAVVFDAEG
Mvan_5594|M.vanbaalenii_PYR-1       MNRQFSSAGEPAIQSKQVTDEELIRAALDAARLAGPRDVPIGAVVFAPDG
TH_1653|M.thermoresistible__bu      -------------MIGSVTDEDMIRAALTAAREAGPRDVPIGAVVFGPDG
MLBr_02474|M.leprae_Br4923          ---MPSAAGRRHQTRSVTTDEDLIRAALTVATTAGSRDVPIGAVVLGADG
Mb0851c|M.bovis_AF2122/97           ----------------------------------MPAGMAGFR-------
Rv0828c|M.tuberculosis_H37Rv        ----------------------------------MPAGMAGFR-------
MMAR_4851|M.marinum_M               -------------------MTDFAQRAIDLARQNVAEGGRPFATVIVKDG
MUL_0449|M.ulcerans_Agy99           -------------------MTDFAQRAIDFARLNVAEGGRPFATVIVKDG
MAV_0777|M.avium_104                -------------------MTDFARRTIDLARQNVAEGGRPFATVIVQDG
MAB_0053c|M.abscessus_ATCC_199      --------------------MDFAQRTIDLARRNVEEGGRPFATIIVKDG
MSMEG_3575|M.smegmatis_MC2_155      -------------MAISDADLKYLRRCVDLAREALDDGDEPFGSVLVDHT
                                                                         .            

Mflv_1214|M.gilvum_PYR-GCK          TELARAANAREELGDPTAHAEILALRAAALVHGDGWRLEGATLAVTVEPC
Mvan_5594|M.vanbaalenii_PYR-1       RELARAANAREEFGDPTAHAEILALRAAARELGDGWRLEGATLAVTVEPC
TH_1653|M.thermoresistible__bu      GELARAANAREQLGDPTAHAEVLALRAAARRLGDGWRLEGATLAVTVEPC
MLBr_02474|M.leprae_Br4923          NELARAVNAREAIGDPTAHAEILAMRAAAGTLGNGWRLEGTTLAVTVEPC
Mb0851c|M.bovis_AF2122/97           --------RWAQTNDPTAHAESLAIRAACTKLGT-EHLVGTTLNVLAHPC
Rv0828c|M.tuberculosis_H37Rv        --------RWAQTNDPTAHAESLAIRAACTKLGT-EHLVGTTLNVLAHPC
MMAR_4851|M.marinum_M               QVLAESANKVAQTNDPTAHAEILAIRAACTKLGT-EQLFGTTFYVLAHPC
MUL_0449|M.ulcerans_Agy99           QVLAESANKVAQTNDPTAHAEILAIRAACTKLGT-EQLFGTTFYVLAHPC
MAV_0777|M.avium_104                EVLAESANKAAQTNDPTAHAEILAIRAACLKLGT-EHLVDATIYVLAHPC
MAB_0053c|M.abscessus_ATCC_199      AVLAESPNRVAQTNDPTAHAEILAIREACTRLGT-EHLAGSTIFILALPC
MSMEG_3575|M.smegmatis_MC2_155      GTTLFEDRNRVKDGDATAHPEFAIARWAARHLTP-DRRARATVYTSGEHC
                                                 .*.***.*    * *.       :   :*.      *

Mflv_1214|M.gilvum_PYR-GCK          TMCAGALVMARVARVVFG--------------AWEPKTGAVGSLWDVVRD
Mvan_5594|M.vanbaalenii_PYR-1       TMCAGALVMARVARVVFG--------------AWEPKTGAVGSLWDVVRD
TH_1653|M.thermoresistible__bu      TMCAGALVLARVARLVFG--------------AWEPKTGAVGSLWDVVRD
MLBr_02474|M.leprae_Br4923          TMCAGALVLARIERLVFG--------------AWQPKTGAVGSLWDVVRD
Mb0851c|M.bovis_AF2122/97           PMCYGSLYYCSPDEVVFLTSRDAYEPHYVDDRRYFEPATFYDEFAKEWQD
Rv0828c|M.tuberculosis_H37Rv        PMCYGSLYYCSPDEVVFLTSRDAYEPHYVDDRRYFEPATFYDEFAKEWQD
MMAR_4851|M.marinum_M               PMCLGSLYYCSPDEVIFLTTRDIYEQYYVDDRKYFELATFYDEFAKAWQD
MUL_0449|M.ulcerans_Agy99           PMCLGS--------------------------------------------
MAV_0777|M.avium_104                PMCLGALYYCSPREVIFLTTRESYEPYYVDDRKYFELSNFYAEFAKPFDE
MAB_0053c|M.abscessus_ATCC_199      PMCLGALYYCSPDEVVFLTTREAYQPHYVDDRKYFEFNTFYGEFAKPWDR
MSMEG_3575|M.smegmatis_MC2_155      PMCAAAHAWVGLGRIVYAT-----------------SSAQLGGWLTEWGA
                                    .** .:                                            

Mflv_1214|M.gilvum_PYR-GCK          RRLTHRPQVRGGVL--EAECAAPLEEFFARQR---------
Mvan_5594|M.vanbaalenii_PYR-1       RRLTHRPQVRGGVL--EAECAAPLEEFFAGQR---------
TH_1653|M.thermoresistible__bu      RRLNHRPEVRGGVL--AAECAAPLEEFFARQRDPDSPRGLG
MLBr_02474|M.leprae_Br4923          HRLNHRPAVRGGVL--AQECTAPLEAFFAHQRLSKGPPVR-
Mb0851c|M.bovis_AF2122/97           RRLPMRQEHRPDIRAGAVDVYRFRQEPNGGERSAIAAPTG-
Rv0828c|M.tuberculosis_H37Rv        RRLPMRQEHRPDIRAGAVDVYRFRQEPNGGERSAIAAPTG-
MMAR_4851|M.marinum_M               RRLPMRYDPRPSA----VNVYRFWQELNGGKRAAAPDAAG-
MUL_0449|M.ulcerans_Agy99           ------------------------QELNGGKRAAAPNSAD-
MAV_0777|M.avium_104                RRLPMRYQPHPDA----VDVYRLWNERNGGRRRSTVVPSD-
MAB_0053c|M.abscessus_ATCC_199      RRLPMHYQARDDA----VDVYRLWQERNGGNRHVAGAPTAT
MSMEG_3575|M.smegmatis_MC2_155      QAPPVATLPINTVAP-GVVVDGPAEELAETMHNLYRAKFGR
                                                            :      :