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M. gilvum PYR-GCK Mflv_3332 (-)

annotation: CMP/dCMP deaminase, zinc-binding
coordinates: 3515732 - 3516223
length: 163

VRRLRPMAVTGDDLRHLRRCVELAREAQDAGDEPFGSLLLDADGVTRVEDRNRVKDGDATRHPEYAIAKW
AVENLSPDDRATVYTSGEHCPMCAAAHAWVGLGRVVYAASSVQLAQWLVEWKAPPPPVASLPITTVAPGV
PVDGPAPELTEEMKTLYERAFRR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3332--100% (163)CMP/dCMP deaminase, zinc-binding
M. gilvum PYR-GCKMflv_1214-6e-0531.53% (111) CMP/dCMP deaminase, zinc-binding

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3141-2e-0627.72% (101) hypothetical protein Mb3141
M. tuberculosis H37RvRv3114-2e-0627.72% (101) hypothetical protein Rv3114
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3459-2e-5869.33% (150) putative cytidine/deoxycytidylate deaminase
M. marinum M-----
M. avium 104MAV_0777-3e-0526.42% (106) cytidine/deoxycytidylate deaminase
M. smegmatis MC2 155MSMEG_3575-2e-6169.81% (159) cytidine/deoxycytidylate deaminase, zinc-binding region
M. thermoresistible (build 8)TH_2296-2e-6471.52% (158) cytidine/deoxycytidylate deaminase, zinc-binding region
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_3058-4e-6878.48% (158) CMP/dCMP deaminase, zinc-binding

CLUSTAL 2.0.9 multiple sequence alignment


Mb3141|M.bovis_AF2122/97            MVAARLPFGWPADSGVTADIIEAAMELAIDTARHATAPFGAALLDVTTLR
Rv3114|M.tuberculosis_H37Rv         MVAARLPFGWSADSGVTADIIEAAMELAIDTARHATAPFGAALLDVTTLR
Mflv_3332|M.gilvum_PYR-GCK          ----MRRLRPMAVTGDDLRHLRRCVELAREAQDAGDEPFGSLLLDADGVT
Mvan_3058|M.vanbaalenii_PYR-1       ----------MAVTDDDLVFLRRCVSLARTALDGGDEPFGSLLVDHEGSV
MSMEG_3575|M.smegmatis_MC2_155      ----------MAISDADLKYLRRCVDLAREALDDGDEPFGSVLVDHTGTT
TH_2296|M.thermoresistible__bu      ----------VAIGDDDLRYLHRCVELARAALAAGDEPFGSILVDADGQI
MAB_3459|M.abscessus_ATCC_1997      ------------MDDNDIQHLRRCVELATEALDAGDEPFGSLLTGPDGAV
MAV_0777|M.avium_104                ----------------MTDFARRTIDLARQNVAEGGRPFATVIVQ-DGEV
                                                         .  :.**      .  **.: :       

Mb3141|M.bovis_AF2122/97            AFSGGNTYFESGDRFAHAETNVLRAAMSTLPELS--NHVLISTAEPCPMC
Rv3114|M.tuberculosis_H37Rv         AFSGGNTYFESGDRFAHAETNVLRAAMSTLPELS--NHVLISTAEPCPMC
Mflv_3332|M.gilvum_PYR-GCK          RVEDRNR-VKDGDATRHPEYAIAKWAVENLSPD--DRATVYTSGEHCPMC
Mvan_3058|M.vanbaalenii_PYR-1       RFEDHNR-VKDGDATRHPEFAIARWAVEHLSPAQRNRSTVYTSGEHCPMC
MSMEG_3575|M.smegmatis_MC2_155      LFEDRNR-VKDGDATAHPEFAIARWAARHLTPDRRARATVYTSGEHCPMC
TH_2296|M.thermoresistible__bu      RYEDRNR-VSGGDRTRHPEFAIARWAAQHLGPDERGRATVYTSGEHCPMC
MAB_3459|M.abscessus_ATCC_1997      LAEDRNR-VGAGDPTRHPEFELARWSVRNLSPTDRALSTVYTSGEHCPMC
MAV_0777|M.avium_104                LAESANKAAQTNDPTAHAEILAIRAACLKLGTEHLVDATIYVLAHPCPMC
                                      .. *     .*   *.*    : :   *        .:   .. ****

Mb3141|M.bovis_AF2122/97            AAASVLSGVRAIIFGTSIETLIQCG-----WFQIRISASDVVAASTRPTR
Rv3114|M.tuberculosis_H37Rv         AAASVLSGVRAIIFGTSIETLIQCG-----WFQIRISASDVVAASTRPTR
Mflv_3332|M.gilvum_PYR-GCK          AAAHAWVGLGRVVYAASSVQLAQW------LVEWKAPPPPVASLPITTVA
Mvan_3058|M.vanbaalenii_PYR-1       AAAHAWVGLGRVVYAASSAQLAQW------LREWGVPAPPVATLPIATVA
MSMEG_3575|M.smegmatis_MC2_155      AAAHAWVGLGRIVYATSSAQLGGW------LTEWGAQAPPVATLPINTVA
TH_2296|M.thermoresistible__bu      AAAHAWVGLGRIVYAASAAQLSGW------LAEWGAPPGPVAPLPVTVVA
MAB_3459|M.abscessus_ATCC_1997      SAAHAWVGLGRIVYASSSAQLTQW------LTELGAPPSPVASLSINEVA
MAV_0777|M.avium_104                LGALYYCSPREVIFLTTRESYEPYYVDDRKYFELSNFYAEFAKPFDERRL
                                     .*    .   ::: ::               :       ..        

Mb3141|M.bovis_AF2122/97            PSVYSGFLSHKTDLLYRNSENRRAMNPWTDPSH
Rv3114|M.tuberculosis_H37Rv         PSVYSGFLSHKTDLLYRNSENRRAMNPWTDPSH
Mflv_3332|M.gilvum_PYR-GCK          PGVPVDGPAPELTEEMKTLYERAFRR-------
Mvan_3058|M.vanbaalenii_PYR-1       PGVDVDGPAAELTEEMKALYARAFRA-------
MSMEG_3575|M.smegmatis_MC2_155      PGVVVDGPAEELAETMHNLYRAKFGR-------
TH_2296|M.thermoresistible__bu      PGLVADGPAAELTETMRELYERKFRP-------
MAB_3459|M.abscessus_ATCC_1997      PGVQTDGPAPDLAEDVRALHVRFLGDA------
MAV_0777|M.avium_104                PMRYQPHPDAVDVYRLWNERNGGRRRSTVVPSD
                                    *