For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2218 | - | - | 100% (443) | dehydrogenase |
| M. thermoresistible (build 8) | TH_1173 | ndh | 2e-33 | 28.84% (423) | PROBABLE NADH DEHYDROGENASE NDH |
| M. thermoresistible (build 8) | TH_1143 | - | 5e-17 | 27.99% (418) | dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1885c | ndh | 2e-35 | 28.47% (425) | NADH dehydrogenase |
| M. gilvum PYR-GCK | Mflv_3348 | - | 2e-36 | 29.50% (417) | FAD-dependent pyridine nucleotide-disulphide oxidoreductase |
| M. tuberculosis H37Rv | Rv1854c | ndh | 1e-35 | 28.47% (425) | NADH dehydrogenase |
| M. leprae Br4923 | MLBr_02061 | - | 4e-36 | 28.71% (425) | putative dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2429c | - | 7e-35 | 28.33% (420) | NADH dehydrogenase (NDH) |
| M. marinum M | MMAR_0689 | ndh_1 | 2e-35 | 30.60% (415) | NADH dehydrogenase Ndh_1 |
| M. avium 104 | MAV_4103 | - | 0.0 | 77.78% (432) | dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4433 | - | 1e-150 | 60.27% (438) | dehydrogenase |
| M. ulcerans Agy99 | MUL_3025 | ndh | 2e-35 | 28.71% (425) | NADH dehydrogenase Ndh |
| M. vanbaalenii PYR-1 | Mvan_2953 | - | 8e-38 | 29.23% (455) | FAD-dependent pyridine nucleotide-disulphide oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1885c|M.bovis_AF2122/97 MSPQQEPTAQPP---------------RRHRVVIIGSGFGGLNAAKKLKR
Rv1854c|M.tuberculosis_H37Rv MSPQQEPTAQPP---------------RRHRVVIIGSGFGGLNAAKKLKR
MUL_3025|M.ulcerans_Agy99 MSPQPETTAQAR---------------PRHRVVIIGSGFGGLNAAKKLKR
MLBr_02061|M.leprae_Br4923 MNAQPAATAAQD---------------RRHQVVIIGSGFGGLNAAKKLKR
Mflv_3348|M.gilvum_PYR-GCK MS---HPGATPS---------------DRHKVVIIGSGFGGLTAAKALKK
MAB_2429c|M.abscessus_ATCC_199 MSTTPDAAGAAAPVAANPQPKIQDALTPKHRVVIIGSGFGGLTAAKTLKR
MMAR_0689|M.marinum_M MTPPSSESSAAG---------------RRHHVVIIGSGFGGLSAARALKR
Mvan_2953|M.vanbaalenii_PYR-1 MVG------------------------RRLRVVIIGGGFGGLFCARRLAR
TH_2218|M.thermoresistible__bu ----------------------------MTSVVIVGSGFAGFECARHLSD
MAV_4103|M.avium_104 --------------------------------MIVGSGFTGFTCARRLAK
MSMEG_4433|M.smegmatis_MC2_155 --------------------------MRPARIVIVGSGFAGFECARRLSK
:*:*.** *: .*: *
Mb1885c|M.bovis_AF2122/97 ------ADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQ
Rv1854c|M.tuberculosis_H37Rv ------ADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQ
MUL_3025|M.ulcerans_Agy99 ------ADVDIKLIARTTHHLFQPLLYQVATGIISEGDIAPPTRVVLRRQ
MLBr_02061|M.leprae_Br4923 ------ANVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQ
Mflv_3348|M.gilvum_PYR-GCK ------ADVDIKMIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRNQ
MAB_2429c|M.abscessus_ATCC_199 ------ANADVTLIARTTHHLFQPLLYQVATGIISEGEIAPPTRQILKDQ
MMAR_0689|M.marinum_M ------ADVDITLISKTTTHLFQPLLYQVATGILSEGDIAPTTRLILRRQ
Mvan_2953|M.vanbaalenii_PYR-1 ------ADVDVTVLDRTAGHLFQPLLYQCATGTLSIGHISRPLREEFAGH
TH_2218|M.thermoresistible__bu KLRRQQAPVDITMISPVDYMLYTPLLPDVAGGVVDARFVTVPLANTLR--
MAV_4103|M.avium_104 TLRR--APVDITMISPVDYMLYTPLLPDVAGGVVDARFVAVPLANSLR--
MSMEG_4433|M.smegmatis_MC2_155 QLKRHRSEAVVTLISPVDYLLYTPLLPEVAGGATDPRFATVPLNDRLP--
: . :.:: . *: *** : * * . : . :
Mb1885c|M.bovis_AF2122/97 RNVQVLLGNVTHIDLAGQCVVSELLG-HTYQTPYDSLIVAAGAGQSYFGN
Rv1854c|M.tuberculosis_H37Rv RNVQVLLGNVTHIDLAGQCVVSELLG-HTYQTPYDSLIVAAGAGQSYFGN
MUL_3025|M.ulcerans_Agy99 RNAQVLLGNVTHIDLAKQSVVSDLLG-HTYETPYDTLIVAAGAGQSYFGN
MLBr_02061|M.leprae_Br4923 RNIQVLLGNVTHIDLANQCVVSELLG-HTYETLYDSLIVAAGAGQSYFGN
Mflv_3348|M.gilvum_PYR-GCK KNAQVLLGDVTRIDLKTNTVRSELLG-HTYITPFDSLIVAAGAGQSYFGN
MAB_2429c|M.abscessus_ATCC_199 DNAQVVLGDVTSIDLEKQVVHSSLLG-HDYSTPYDSLIVAAGAGQSYFGN
MMAR_0689|M.marinum_M KNVRVLLGEVMGIDLNAQTVTSKLMD-MTTVSPYDSLIVAAGAQQSYFGN
Mvan_2953|M.vanbaalenii_PYR-1 PNITTLLGEAVALDPERRTVTALRPDETTFTIDYDVLVVAAGMQQSYFGK
TH_2218|M.thermoresistible__bu -GVRTARGWVDSVDFDARTVSFTDPEDRTHTVAWDRLVLTPGSVTRLFDI
MAV_4103|M.avium_104 -GMHAVRGRVDAVDFTGRTLTYRDPEERSHSMSWDRLVLTPGSVTKLFDV
MSMEG_4433|M.smegmatis_MC2_155 -EVQFIRAYVDSVDLSARSLRCRDQENMSHELSWDRLVLTPGSISRLFDI
. . :* . : :* *:::.* *.
Mb1885c|M.bovis_AF2122/97 DHFAEFAPGMKSIDDALELRGRILSAFEQAERSSDPERRAKLLTFTVVGA
Rv1854c|M.tuberculosis_H37Rv DHFAEFAPGMKSIDDALELRGRILSAFEQAERSSDPERRAKLLTFTVVGA
MUL_3025|M.ulcerans_Agy99 DHFAEFAPGMKSIDDALELRGRILSAFEQAERSRDAERRAKLLTFTVVGA
MLBr_02061|M.leprae_Br4923 DQFAEFAPGMKSIDDALELRGRILSAFEQAERSNDPERREKLLTFTVVGA
Mflv_3348|M.gilvum_PYR-GCK DHFAEWAPGMKSIDDALELRGRILGSFEQAERSSDPARREKLLTFVVVGA
MAB_2429c|M.abscessus_ATCC_199 DHFAEWAPGMKSIDDALELRGRILGAFEQAERSSDPVRRRKLMTFTVVGA
MMAR_0689|M.marinum_M DDFAIFAPGMKTIDDALELRGRILGAFEAAEVATDHDERERRLTFVVVGA
Mvan_2953|M.vanbaalenii_PYR-1 PHFAQWAPGMKTLDDALSIRQRIFTAFEIAETLPPGAERDAWLTFAVTGG
TH_2218|M.thermoresistible__bu PGLAEHARGLKSTAEALYLRDHFLQQLQLSCIDDDPDEIAARRTVVVVGA
MAV_4103|M.avium_104 PGLARHARGLKTTAEALYLRDHFVEQLELANIEDDPRVAAARRTVVVVGA
MSMEG_4433|M.smegmatis_MC2_155 PGLAEHGRGLKSTAQALFLRDHIIEQFELARIDEDRERANARKTVVVVGS
:* . *:*: :** :* ::. :: : *..*.*.
Mb1885c|M.bovis_AF2122/97 GPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKL
Rv1854c|M.tuberculosis_H37Rv GPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKL
MUL_3025|M.ulcerans_Agy99 GPTGVEMAGQIAELAEHTLKGAFRHIDSTRARVILLDAAPAVLPPFGDKL
MLBr_02061|M.leprae_Br4923 GPTGVEMAGQIAELADHTLKGAFRRIDSTKARVVLLDAAPAVLPPMGEKL
Mflv_3348|M.gilvum_PYR-GCK GPTGVEMAGQIAELADHTLKGAFRHIDSTKARVILLDAAPAVLPPMGEKL
MAB_2429c|M.abscessus_ATCC_199 GPTGVEMAGQIAELANETLKGTFRHIDPTDARVILLDAAPAVLPPFGPKL
MMAR_0689|M.marinum_M GPTGVELAGEIVQLAERTLAGAFRTITPSECRVILLDAAPAVLPPMGPKL
Mvan_2953|M.vanbaalenii_PYR-1 GPTGVELAGQIREMATRTLTNEFHSIEPEEARVLLFDGGDRVLKSFAPEL
TH_2218|M.thermoresistible__bu SYSGTELVAQLRALADTAAEQMG--FDPAEVRFVLLDLAEQVMPEVGEKL
MAV_4103|M.avium_104 SYSGTELVAQLRALADAAARQMG--FDPGAVRFLLLDLAEQVMPEVGKKL
MSMEG_4433|M.smegmatis_MC2_155 SYSGTELIAQLCAMASVAVHDFG--FEPGDVRLILVERSGRLMPEIGPAL
. :*.*: .:: :* : : . *.:*.: . :: .. *
Mb1885c|M.bovis_AF2122/97 GQRAAARLQKLGVEIQLGAMVTDVDRNGITVK-DSDGTVRRIESACKVWS
Rv1854c|M.tuberculosis_H37Rv GQRAAARLQKLGVEIQLGAMVTDVDRNGITVK-DSDGTVRRIESACKVWS
MUL_3025|M.ulcerans_Agy99 GERAAARLQKLGVEIQLGAMVTDVDRNGITVK-DSDGTIRRIESACKVWS
MLBr_02061|M.leprae_Br4923 GQRAAARLQKMGVEIQLSAMVTDVDRNGITVQ-DSDGTVRRIESACKVWS
Mflv_3348|M.gilvum_PYR-GCK GKQAQKRLEKMGVEIQLNAMVTDVDRNGITVK-DPDGTMRRIEAACKVWS
MAB_2429c|M.abscessus_ATCC_199 GDKARKRLEKLGVEIQLSAMVTDVDRNGLTVK-HADGSIERIESWCKVWS
MMAR_0689|M.marinum_M GLKAQKKLEKMDVEIQLNAMVTAVDYKGITVK-DKDGTERRIDCACKVWA
Mvan_2953|M.vanbaalenii_PYR-1 SGRAAGTLRSLGVDVRLGVHVTDVQREGVTVAPKSGGSEEYYAVRTVLWT
TH_2218|M.thermoresistible__bu GTAAMQVLRHRGIDVRLGLTLSEVHADHVVLS---DGS--RVGTRTVAWL
MAV_4103|M.avium_104 GDAALKVLRRRGIDVRLGTTLKEAHADHVVLS---DGS--RIDTHTIAWV
MSMEG_4433|M.smegmatis_MC2_155 AVRAEHVLKRRGVRFLTGVTLSRVAADHVILS---DGT--RIGTYTVAWV
. * *. .: . . :. . . : : .*: *
Mb1885c|M.bovis_AF2122/97 AGVSASWLGRDLAEQS-RVELDRAGRVQVLPDLSIPGYPNVFVVGDMAAV
Rv1854c|M.tuberculosis_H37Rv AGVSASRLGRDLAEQS-RVELDRAGRVQVLPDLSIPGYPNVFVVGDMAAV
MUL_3025|M.ulcerans_Agy99 AGVQASRLGRDLAEQS-EVELDRAGRVQVLPDLSVPGHPNVFVIGDMAAV
MLBr_02061|M.leprae_Br4923 AGVSASRLGRDLAEQS-LVELDWAGRVKVLPDLSIPGYRNVFVVGDMAAI
Mflv_3348|M.gilvum_PYR-GCK AGVSASPLGRDLADQS-GVELDRAGRVKVLPDLSIPGHPNVFVVGDMAAV
MAB_2429c|M.abscessus_ATCC_199 AGVSASPLGKNLAEQS-GVELDRAGRVKVGPDLSIPGHPNVFVVGDMMAV
MMAR_0689|M.marinum_M AGVQASPLGKMIAEQSDGTETDRAGRVIVEPDLTVKGHPHVFVIGDLMSV
Mvan_2953|M.vanbaalenii_PYR-1 AGVEAVPFAGHLAEVL-DVQADRAGRLAVQPDLSVPGHPEIFVIGDLVGR
TH_2218|M.thermoresistible__bu TGVTAAPLIETLGLPT------TKGRLEVDAELRVPDRPDVFAAGDAAAV
MAV_4103|M.avium_104 TGVTGAPLIQDLGLPT------EKGRLKVQPDLQVPGHPGVFAAGDAAAV
MSMEG_4433|M.smegmatis_MC2_155 AGVVASPLITATGLPT------EKGRLKVGPDLQVPGFDGVFAGGDAAAV
:** . : . **: * .:* : . :*. ** .
Mb1885c|M.bovis_AF2122/97 EG---------VPGVAQGAIQGAKYVASTIKAELAGAN-PAEREPFQYFD
Rv1854c|M.tuberculosis_H37Rv EG---------VPGVAQGAIQGAKYVASTIKAELAGAN-PAEREPFQYFD
MUL_3025|M.ulcerans_Agy99 EG---------VPGVAQGAIQGAKYVATTIKSELAGAN-AAEREPFQYFD
MLBr_02061|M.leprae_Br4923 DG---------VPGVAQGAIQGAKYVANNIKAELGEAN-PAEREPFQYFD
Mflv_3348|M.gilvum_PYR-GCK ED---------VPGMAQGAIQGGRYAAKAIAAGLKGAE-VSEREPFKYFD
MAB_2429c|M.abscessus_ATCC_199 DG---------VPGVAQGAIQGGRYAAKQIKAELKGRS-PAERAPFKFFD
MMAR_0689|M.marinum_M PG---------VPGMAQGAIQGAHYATKTIKQAVKGHDDPANRKPFQYFN
Mvan_2953|M.vanbaalenii_PYR-1 DD---------LPGVAENAMQGGLHVAACIRRDLAGRP----RRNYRYRD
TH_2218|M.thermoresistible__bu PDLAQPDPERITPPTAQHATRQGKVLANNVAASLGYGR----MKQYRHRN
MAV_4103|M.avium_104 PDLTQPG--KITPPTAQHATRQGKVLARNVAASLGHGS----AKEYKHRN
MSMEG_4433|M.smegmatis_MC2_155 PDVTNPG--TITPPTAQHATRQGKILARNVAASLGYGS----AREYRHRD
. * *: * : . : : : ::. :
Mb1885c|M.bovis_AF2122/97 KGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLHLAYLIGFKTKITTLLS
Rv1854c|M.tuberculosis_H37Rv KGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLHLAYLIGFKTKITTLLS
MUL_3025|M.ulcerans_Agy99 KGSMATVSRFSAVAKIGPVEISGFIAWLAWLVLHLVYLVGFKTKVSTLLS
MLBr_02061|M.leprae_Br4923 KGSMATVSRFSAVAKIGPLEFSGFIAWLMWLVLHLMYLIGFKTKITTLLS
Mflv_3348|M.gilvum_PYR-GCK KGSMATVSRFSAVAKIGPLEFGGFIAWLSWLVLHLVYLVGFKTKIVTLLS
MAB_2429c|M.abscessus_ATCC_199 KGSMATVSRYSAVVKIGKIEFSGFIAWLSWLALHLVYLVGFKNRLVTLIL
MMAR_0689|M.marinum_M KGSMALISHYSAVAKVGKVEFAGFIAWLAWLFLHLLYLVGHRNRVAAAFS
Mvan_2953|M.vanbaalenii_PYR-1 LGSAAYISRGNALLQVGPVKVAGFLGWIAWGLLHIAFLTGVRNRVSTVVT
TH_2218|M.thermoresistible__bu MGLVVDLGPRYAVANPLNVHLSGFPAKAVARGYHLYAIPRFVNRWAVALA
MAV_4103|M.avium_104 LGLVVDLGPRYAVANPLNIHLSGLPAKAVTRGYHLYAIPRGVNRWAVSLA
MSMEG_4433|M.smegmatis_MC2_155 LGTVVDLGPGFAVANPLNIPLSGFLAKLVTRAYHLYAIPRNANRWAVALG
* . :. *: : : ..*: . *: : .: . .
Mb1885c|M.bovis_AF2122/97 WTVTFLSTRR----------------------------------------
Rv1854c|M.tuberculosis_H37Rv WTVTFLSTRR----------------------------------------
MUL_3025|M.ulcerans_Agy99 WTVTFLSTRR----------------------------------------
MLBr_02061|M.leprae_Br4923 WTVTFLSTRR----------------------------------------
Mflv_3348|M.gilvum_PYR-GCK WTVTFLSTKR----------------------------------------
MAB_2429c|M.abscessus_ATCC_199 WSIAFVTRSR----------------------------------------
MMAR_0689|M.marinum_M WGLAFLGRTR----------------------------------------
Mvan_2953|M.vanbaalenii_PYR-1 WLATIARASRYHRAFMLGSVSAPEARYTWSSRDQPTPPQALCEDPRTGHT
TH_2218|M.thermoresistible__bu YLTDALFDRS---------------------------------------V
MAV_4103|M.avium_104 YLTDALFARS---------------------------------------V
MSMEG_4433|M.smegmatis_MC2_155 YLTNVLFGRP---------------------------------------L
:
Mb1885c|M.bovis_AF2122/97 GQLTITDQ--------------------------------------QAFA
Rv1854c|M.tuberculosis_H37Rv GQLTITDQ--------------------------------------QAFA
MUL_3025|M.ulcerans_Agy99 GQLTITEQ--------------------------------------QAFA
MLBr_02061|M.leprae_Br4923 GQLTITEQ--------------------------------------QAFA
Mflv_3348|M.gilvum_PYR-GCK GQLTITEQ--------------------------------------QAYA
MAB_2429c|M.abscessus_ATCC_199 GQMAITEQ--------------------------------------QAWA
MMAR_0689|M.marinum_M GQMAITSQ--------------------------------------MVYA
Mvan_2953|M.vanbaalenii_PYR-1 SHMTISAQDVRRLLDAEHDSTLVLIEGRTEVITGQQKSSDQYRGAFEVIS
TH_2218|M.thermoresistible__bu VSIGLSSKE------------------------------------DASFA
MAV_4103|M.avium_104 VSIGLSSED------------------------------------DAQFT
MSMEG_4433|M.smegmatis_MC2_155 VSIGFAQPS------------------------------------WAQFS
: :: :
Mb1885c|M.bovis_AF2122/97 RTRLEQLAELAAEAQGSAASAKVAS--------------------
Rv1854c|M.tuberculosis_H37Rv RTRLEQLAELAAEAQGSAASAKVAS--------------------
MUL_3025|M.ulcerans_Agy99 RTRLEQLAELASEAQ--STEARQAS--------------------
MLBr_02061|M.leprae_Br4923 RTRLEQLAELTAESQSTAAANRATMRAS-----------------
Mflv_3348|M.gilvum_PYR-GCK RIRLEELEEIAASVQDTEKAAS-----------------------
MAB_2429c|M.abscessus_ATCC_199 RTRLDQLEELVAEKNGDEEPTTQPDKEKAAS--------------
MMAR_0689|M.marinum_M RLAMRYLQARAEEDALSAAEHAEQAEQRATG--------------
Mvan_2953|M.vanbaalenii_PYR-1 RDELLSRTGGAAHLTDDQISAQAAALDTAVNELGG----------
TH_2218|M.thermoresistible__bu VSQR-IPPPKQPTPGD-----------------------------
MAV_4103|M.avium_104 ASEG-IPMPKTG---------------------------------
MSMEG_4433|M.smegmatis_MC2_155 ASEEFMTAPTATQPLDEQMYTDDLRFQEASADRASAPGDRARKAT