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M. thermoresistible (build 8) TH_2130 (nth)

annotation: PROBABLE ENDONUCLEASE III NTH (DNA-(APURINIC OR APYRIMIDINIC SITE)LYASE) (AP LYASE) (AP ENDONUCLEASE CLASS I) (ENDODEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC)) (DEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC))
coordinates: 4179770 - 4180417
length: 216

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2130 nth - 100% (216) PROBABLE ENDONUCLEASE III NTH (DNA-(APURINIC OR APYRIMIDINIC SITE)LYASE) (AP LYASE) (AP ENDONUCLEASE CLASS I) (ENDODEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC)) (DEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC))
M. thermoresistible (build 8) TH_0591 mutY 2e-07 26.86% (175) PROBABLE ADENINE GLYCOSYLASE MUTY

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3698c nth 1e-102 82.79% (215) endonuclease III
M. gilvum PYR-GCK Mflv_1373 - 1e-106 85.58% (215) endonuclease III
M. tuberculosis H37Rv Rv3674c nth 1e-102 82.79% (215) endonuclease III
M. leprae Br4923 MLBr_02301 nth 1e-105 84.19% (215) putative endonuclease III
M. abscessus ATCC 19977 MAB_0418 - 1e-102 81.40% (215) endonuclease III protein
M. marinum M MMAR_5162 nth 1e-106 85.58% (215) endonuclease III Nth
M. avium 104 MAV_0455 nth 1e-101 81.31% (214) endonuclease III
M. smegmatis MC2 155 MSMEG_6187 nth 1e-110 88.37% (215) endonuclease III
M. ulcerans Agy99 MUL_4248 nth 1e-107 85.58% (215) endonuclease III Nth
M. vanbaalenii PYR-1 Mvan_5433 - 1e-106 86.05% (215) endonuclease III

CLUSTAL 2.0.9 multiple sequence alignment


TH_2130|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6187|M.smegmatis_MC2_155      -----MSAG-AARAAKPKKSDAKKWDSETHLGLVRRARRMNRTLAKAFPH
Mflv_1373|M.gilvum_PYR-GCK          -----MTVSEPSTGAKSARRSARKWDRETHLGLVRRARRMNRTLTQAFPH
Mvan_5433|M.vanbaalenii_PYR-1       -----MTVK-PARGA-SPRKSGRKWDEETHLGLVRRARRMNRTLAQAFPH
MMAR_5162|M.marinum_M               -----MSGGSKPTANASTPKLPKRWSEETRTALVRRARRMNRKLAQAFPH
MUL_4248|M.ulcerans_Agy99           --------------------------------MVRRARRMNRKLAQAFPH
Mb3698c|M.bovis_AF2122/97           --------------------MPGRWSAETRLALVRRARRMNRALAQAFPH
Rv3674c|M.tuberculosis_H37Rv        --------------------MPGRWSAETRLALVRRARRMNRALAQAFPH
MLBr_02301|M.leprae_Br4923          ------------MPLTPGVDVARRWSGETRLGLVRRARRMNRALAQAFPH
MAV_0455|M.avium_104                ---------------------------------MRRARRMNRILAQAFPE
MAB_0418|M.abscessus_ATCC_1997      MPTTGSAAKPRAKSSVKAPAPVRAWKPETHTGLVRRARRMNRTLAQAFPH
                                                                                      

TH_2130|M.thermoresistible__bu      VYCELDFTNPLELTVATILSAQSTDKRVNLTTPALFRKYRTALDYAQADR
MSMEG_6187|M.smegmatis_MC2_155      VYCELDFTNPLELTVATILSAQSTDKRVNLTTPALFKKYRTALDYAQADR
Mflv_1373|M.gilvum_PYR-GCK          VYCELDFTNPLELTVATILSAQSTDKRVNLTTPALFAKYRTARDYATADR
Mvan_5433|M.vanbaalenii_PYR-1       VYCELDFTDPLELTVATILSAQSTDKRVNLTTPALFKKYRTARDYATADR
MMAR_5162|M.marinum_M               VYCELDFTSPLELAVATILSAQSTDKRVNLTTPDLFVKYQTALDYAQADR
MUL_4248|M.ulcerans_Agy99           VYCELDFTSPLELAVATILSAQSTDKRVNLTTPDLFAKYQTALDYAQADR
Mb3698c|M.bovis_AF2122/97           VYCELDFTTPLELAVATILSAQSTDKRVNLTTPALFARYRTARDYAQADR
Rv3674c|M.tuberculosis_H37Rv        VYCELDFTTPLELAVATILSAQSTDKRVNLTTPALFARYRTARDYAQADR
MLBr_02301|M.leprae_Br4923          VYCELDFTSPLELTVATILSAQSTDKRVNLTTPAVFARYRSALDYMQADR
MAV_0455|M.avium_104                AHCELDFTTPLELTVATILSAQSTDKRVNLTTRALFKRYTCALDYAQADR
MAB_0418|M.abscessus_ATCC_1997      VYCELDFTNPLELAVATILSAQCTDVRVNMVTPALFAKYRTAEDYAGANR
                                    .:****** ****:********.** ***:.*  :* :*  * **  *:*

TH_2130|M.thermoresistible__bu      AELEELIRPTGFFRTKANSLIRLGQELVERFDGEVPDNLEDLVTLPGVGR
MSMEG_6187|M.smegmatis_MC2_155      TELEELIRPTGFYRNKANSLIKLGQELVERFDGEVPKTLDELVTLPGVGR
Mflv_1373|M.gilvum_PYR-GCK          TELEELIRPTGFYRNKATSLIGLGQALEERFDGEVPRTLDELVTLPGIGR
Mvan_5433|M.vanbaalenii_PYR-1       TELEELIRPTGFYRNKANSLIGLGQALEERFDGQVPRTLDELVTLPGVGR
MMAR_5162|M.marinum_M               AELENLIRPTGFYRNKANSLIGLGQALVERFDGQVPATMEELVTLPGVGR
MUL_4248|M.ulcerans_Agy99           AELENLIRPTGFYRNKANSLIGLGQALVERFDGQVPATMEELVTLPGVGR
Mb3698c|M.bovis_AF2122/97           TELESLIRPTGFYRNKAASLIGLGQALVERFGGEVPATMDKLVTLPGVGR
Rv3674c|M.tuberculosis_H37Rv        TELESLIRPTGFYRNKAASLIGLGQALVERFGGEVPATMDKLVTLPGVGR
MLBr_02301|M.leprae_Br4923          AELENFIRPTGFFRNKAASLIRLGQALVERFDGEVPSTMVDLFTLPGVGR
MAV_0455|M.avium_104                DELENLIRPTGFFRNKASALIRLGQALVERFDGEVPATMAELVTLPGVGR
MAB_0418|M.abscessus_ATCC_1997      AELEEMIRTTGFYRNKANSIMGLGTQLVERFGGEIPPRLKDLVTLPGIGR
                                     ***.:**.***:*.** ::: **  * ***.*::*  : .*.****:**

TH_2130|M.thermoresistible__bu      KTANVILGNAFDVPGITVDTHFGRLVRRWRWTDERDPVKVEHAVGKLIER
MSMEG_6187|M.smegmatis_MC2_155      KTANVILGNAFDIPGITVDTHFGRLVRRWRWTDHEDPVKVEFAVAELIER
Mflv_1373|M.gilvum_PYR-GCK          KTANVVLGNAFDIPGITVDTHFGRLVRRWRWTAEEDPVKVEHIVGDLIER
Mvan_5433|M.vanbaalenii_PYR-1       KTANVILGNAFDIPGITVDTHFGRLVRRWRWTAEEDPVKVEHIVGELIER
MMAR_5162|M.marinum_M               KTANVILGNAFDVPGITVDTHFGRLARRWRWTAEEDPVKVEHAVGELIER
MUL_4248|M.ulcerans_Agy99           KTANVILGNAFDVPGITVDTHFGRLARRWRWTAEEDPVKVEHAVGELIER
Mb3698c|M.bovis_AF2122/97           KTANVILGNAFGIPGITVDTHFGRLVRRWRWTTAEDPVKVEQAVGELIER
Rv3674c|M.tuberculosis_H37Rv        KTANVILGNAFGIPGITVDTHFGRLVRRWRWTTAEDPVKVEQAVGELIER
MLBr_02301|M.leprae_Br4923          KTANVILGNAFGIPGITVDTHFGRLVRRWRWTAEEDPVKVEHAVGELIER
MAV_0455|M.avium_104                KTANVILGNAFGVPGITVDTHFARLVHRWRWTAEKDPVKIEHAVGELIER
MAB_0418|M.abscessus_ATCC_1997      KTANVILGNAFDIPGITVDTHFGRLVRRWRWTEEEDPVKVEHLVGELIER
                                    *****:*****.:*********.**.:*****  .****:*  *..****

TH_2130|M.thermoresistible__bu      REWTLLSHRVIFHGRRVCHARKPACGVCVLADDCPSYGIGETDKLAAAEL
MSMEG_6187|M.smegmatis_MC2_155      SEWTLLSHRVIFHGRRVCHARKPACGVCVLAKDCPSYGIGPTDPPTAAAL
Mflv_1373|M.gilvum_PYR-GCK          SEWTLLSHRVIFHGRRVCHARKPACGVCVLAKDCPSYGTGPTDPLIAAAL
Mvan_5433|M.vanbaalenii_PYR-1       SEWTLLSHRVIFHGRRVCHARKPACGVCVLAKDCPSYGAGPTDPLIAAPL
MMAR_5162|M.marinum_M               KEWTLLSHRVIFHGRRVCHARKPACGVCVLAKDCPSYGLGPTEPLLAAPL
MUL_4248|M.ulcerans_Agy99           KEWTLLSHRVIFHGRRVCHARKPACGVCVLAKDCPSYGLGPTEPLLAAPL
Mb3698c|M.bovis_AF2122/97           KEWTLLSHRVIFHGRRVCHARRPACGVCVLAKDCPSFGLGPTEPLLAAPL
Rv3674c|M.tuberculosis_H37Rv        KEWTLLSHRVIFHGRRVCHARRPACGVCVLAKDCPSFGLGPTEPLLAAPL
MLBr_02301|M.leprae_Br4923          DQWTLLSHRVIFHGRRVCHARKPACGVCVLAKDCPSFGLGPTEPLLAAPL
MAV_0455|M.avium_104                SEWTMLSHRVIFHGRRVCHSRKPACGVCLLARDCPSFGLGPTEPPLAAQL
MAB_0418|M.abscessus_ATCC_1997      KEWTLLSHRVIFHGRRVCHARKPACGVCVLAKDCPSYGLGPTDPEVAAPL
                                     :**:**************:*:******:** ****:* * *:   ** *

TH_2130|M.thermoresistible__bu      VRGPERDHLLALAGL
MSMEG_6187|M.smegmatis_MC2_155      VKGPETEHLLALAGL
Mflv_1373|M.gilvum_PYR-GCK          VKGPETEHLLALAGL
Mvan_5433|M.vanbaalenii_PYR-1       VKGPETEHLLALAGL
MMAR_5162|M.marinum_M               VQGPETEHLLAMAGL
MUL_4248|M.ulcerans_Agy99           VQGPETEHLLAMAGL
Mb3698c|M.bovis_AF2122/97           VQGPETDHLLALAGL
Rv3674c|M.tuberculosis_H37Rv        VQGPETDHLLALAGL
MLBr_02301|M.leprae_Br4923          VQGPEAGHLLALAGL
MAV_0455|M.avium_104                VRGPETEHLLALAGL
MAB_0418|M.abscessus_ATCC_1997      VKGPETEHLLALAGL
                                    *:***  ****:***

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2130	nth	-	100% (216)	PROBABLE ENDONUCLEASE III NTH (DNA-(APURINIC OR APYRIMIDINIC SITE)LYASE) (AP LYASE) (AP ENDONUCLEASE CLASS I) (ENDODEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC)) (DEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC))
M. thermoresistible (build 8)	TH_0591	mutY	2e-07	26.86% (175)	PROBABLE ADENINE GLYCOSYLASE MUTY