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M. thermoresistible (build 8) TH_2028 ()

annotation: POSSIBLE METHYLTRANSFERASE (METHYLASE)
coordinates: 3987566 - 3988384
length: 273

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2028 - 100% (273) POSSIBLE METHYLTRANSFERASE (METHYLASE)
M. thermoresistible (build 8) TH_2193 - 8e-09 37.50% (104) CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8) TH_0087 - 4e-08 28.45% (116) methyltransferase type 11

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0229c - 1e-109 74.32% (257) methyltransferase (methylase)
M. gilvum PYR-GCK Mflv_0427 - 1e-112 77.25% (255) methyltransferase type 11
M. tuberculosis H37Rv Rv0224c - 1e-110 74.71% (257) methyltransferase (methylase)
M. leprae Br4923 MLBr_02584 - 1e-112 73.21% (265) hypothetical protein MLBr_02584
M. abscessus ATCC 19977 MAB_4481 - 1e-108 73.15% (257) hypothetical protein MAB_4481
M. marinum M MMAR_0473 - 1e-114 77.73% (256) methyltransferase
M. avium 104 MAV_4945 - 1e-115 78.60% (257) SAM-dependent methyltransferase
M. smegmatis MC2 155 MSMEG_3286 - 2e-09 34.55% (165) methyltransferase
M. ulcerans Agy99 MUL_1123 - 1e-112 76.95% (256) methyltransferase
M. vanbaalenii PYR-1 Mvan_0241 - 1e-112 76.86% (255) methyltransferase type 11

CLUSTAL 2.0.9 multiple sequence alignment


Mb0229c|M.bovis_AF2122/97           --------------MAVTDVFARRATLRRSLRLLADFRYEQRDPARFYRT
Rv0224c|M.tuberculosis_H37Rv        --------------MAVTDVFARRATLRRSLRLLADFRYEQRDPARFYRT
MLBr_02584|M.leprae_Br4923          MDTRRRVWPVAIITPHVTDVFAQRATLTRSLQLLSEFRYEQPYPARFYRA
MMAR_0473|M.marinum_M               --------------MAVTDRFARRATLSRSLRLLSEFRYEQPDPARFYGA
MUL_1123|M.ulcerans_Agy99           --------------MAVTDRFARRATLSRSLRLLSEFRYEQPDPARFYGA
MAV_4945|M.avium_104                ----------------MTDIFARRATLARSVRLLSQFRYERSEPARFYGA
TH_2028|M.thermoresistible__bu      MDAPR-----AAARRDVTELFARRATLRRSVRLLSEFRFEQSDPARFYGA
Mflv_0427|M.gilvum_PYR-GCK          --------------MAATDLLAGRATLSRSLRLLSAFRFEQTDPDRFYGA
Mvan_0241|M.vanbaalenii_PYR-1       --------------MPATDRFSDRATLARSVRLLTAFRFEQSAPDRFYGA
MAB_4481|M.abscessus_ATCC_1997      -------------MPDITDLFAQRATLRRSTSLLTAFRFEQSAPERFYGT
MSMEG_3286|M.smegmatis_MC2_155      ----------------MPDTVGPQPQYET-----FADEFLDHARDGFYNA
                                                     .: .. :.            .:       ** :

Mb0229c|M.bovis_AF2122/97           LAADTAAMIGDLWLATHSEPPVGRTLLDVGGGPGYFATAFSDAGVGYIGV
Rv0224c|M.tuberculosis_H37Rv        LAADTAAMIGDLWLATHSEPPVGRTLLDVGGGPGYFATAFSDAGVGYIGV
MLBr_02584|M.leprae_Br4923          LAADTVAMVGDLWLSTHGAPPVGRILLDVGSGSGYFAAAFADAGVRYIGV
MMAR_0473|M.marinum_M               LAADTATLVSDLWLAARGESVAGRTLLDVGGGPGYFASAFAAAGVGYIGV
MUL_1123|M.ulcerans_Agy99           LAADTATLVSDLWLAARGESVAGRTLLDVGGGPGYFASAFAAAGVGYIGV
MAV_4945|M.avium_104                LAADTAAMVDDLWRAGHGESAAGRTLLDVGGGPGYFAAAFADAGVRYLGV
TH_2028|M.thermoresistible__bu      LADDTAALVADLWRAATGSDPAGRTVLDVGGGPGYFAAAFARAGMRYIGV
Mflv_0427|M.gilvum_PYR-GCK          LASDTVAMVDDLWRATTGTSTRNLTVLDVGGGPGYFASAFTDAGLHYVGV
Mvan_0241|M.vanbaalenii_PYR-1       LADDTVAMVGDLWESATGESQAGLTLLDVGGGPGYFASAFTAAGVNYIGV
MAB_4481|M.abscessus_ATCC_1997      LAQDTVHLITDLWQQAEGVALRGRTVLDVGGGPGYFASAFADAGARYIGV
MSMEG_3286|M.smegmatis_MC2_155      HYDRPACLA-------LIGDVAGRTILDAACGPGLYAEELAKRGASLIGF
                                        .. :              .  :**.. *.* :*  ::  *   :*.

Mb0229c|M.bovis_AF2122/97           EPDPDEMHAAGPAFTGR----PGMFVRASGMALPLADDSVDICLSSNVAE
Rv0224c|M.tuberculosis_H37Rv        EPDPDEMHAAGPAFTGR----PGMFVRASGMALPFADDSVDICLSSNVAE
MLBr_02584|M.leprae_Br4923          EPDPREMHAAGPALVPK----AGAFVRASGMALPFADDAVDICLSSNVAE
MMAR_0473|M.marinum_M               EPDPNEMHAAGPAHAGG----PGSFVRASGMALPFADDSVDICLSSNVAE
MUL_1123|M.ulcerans_Agy99           EPDPNEMHAAGPAHAGG----PGSFVRASGMALPLADDSVDICLSSNVAE
MAV_4945|M.avium_104                EPDPGEMHAAGPVVAAD----TGTFVRASGMALPFADDSVDICLSSNVAE
TH_2028|M.thermoresistible__bu      EPDPREIHAGPAVECPEDDPAAGTFVRASGMALPFADASVDICLSSNVAE
Mflv_0427|M.gilvum_PYR-GCK          EPDPGEMHAAAPRTHSR----AGSFVRASGTALPFADGSVDICLSSNVAE
Mvan_0241|M.vanbaalenii_PYR-1       EPDPREMHAAAALTHER----AGTFVRASGTALPFADDSVDVCLSSNVAE
MAB_4481|M.abscessus_ATCC_1997      EPDPREMHAAPQGHRGIQDP-RTTYLRASGMALPLADNSVDICLSSNVAE
MSMEG_3286|M.smegmatis_MC2_155      DQSPRMVELARARVPSG----DFRVHDLAGPLDWLPSQSVDAVLLALALE
                                    : .*  :. .                  :*    :.. :**  * : . *

Mb0229c|M.bovis_AF2122/97           HVPRPWQLGTEMLRVTKPGGLVVLSYTVWLGPFG--GHEMGLSHYLGGAR
Rv0224c|M.tuberculosis_H37Rv        HVPRPWQLGTEMLRVTKPGGLVVLSYTVWLGPFG--GHEMGLSHYLGGAR
MLBr_02584|M.leprae_Br4923          HVPQPWQLGNEMLRVTKPGGLVVLSYTIWLGPFG--GHEMGLTHYLGGAR
MMAR_0473|M.marinum_M               HVPRPWQLGAEMLRVTRPGGLAVLSYTVWLGPFG--GHEMGLSHYLGGAR
MUL_1123|M.ulcerans_Agy99           HVPRPWQLGAEMLRVTRPGGLAVLSYTVWLGPFG--GHEMGLSHYLGGAR
MAV_4945|M.avium_104                HVPRPWQLGAEMLRVTRPGGLAVLSYTVWLGPFG--GHEMGLTHYLGGSR
TH_2028|M.thermoresistible__bu      HVPQPWLLGREMLRVTRPGGLAVLSYTVWLGPFG--GHETGLWHYLGGRR
Mflv_0427|M.gilvum_PYR-GCK          HVAQPWRLGEEMLRVTRPGGLAVLSYTVWLGPFG--GHEMGLSHYLGGYR
Mvan_0241|M.vanbaalenii_PYR-1       HVAQPWRLGDEMLRVTRPGGLAVLSYTVWLGPFG--GHEMGLTHYLGGRR
MAB_4481|M.abscessus_ATCC_1997      HVPQPWRLGEEMLRVTRPGGLAILSYTVWLGPFG--GHEMGLTHYFGGAR
MSMEG_3286|M.smegmatis_MC2_155      YVDDRTAMLREFHRVLRPAGALVLSRMHPTGDWLRHGGNYFETRVVEETW
                                    :*     :  *: ** :*.*  :**     * :   * :    : .    

Mb0229c|M.bovis_AF2122/97           AAARYVRKHGHPAKNNYGSSLFAVSAAEGLRWAAGTGAALAVFPRYHPRW
Rv0224c|M.tuberculosis_H37Rv        AAARYVRKHGHPAKNNYGSSLFAVSAAEGLRWAAGTGAALAVFPRYHPRW
MLBr_02584|M.leprae_Br4923          AATRYVRKHGHRAKNDYGSSLFPVSAADGLNWAASTGVAVAAFPRYHPRW
MMAR_0473|M.marinum_M               AAARYARRHGHPAKNNYGSSLFAVSAAEGLRWAEGTGTLIAAFPRYHPRW
MUL_1123|M.ulcerans_Agy99           AAARYARRHGHPAKNNYGSSLFAVSAAEGLRWAEGTGTLIAAFPRYHPRS
MAV_4945|M.avium_104                AAARYARKHGHPAKNNYGSSLFEVSVADGLAWAACTGAELAAFPRYHPRW
TH_2028|M.thermoresistible__bu      AADRYARRHGHRPKNDYGSSLFAVSAADGLRWAAATGALLAAFPRYHPKW
Mflv_0427|M.gilvum_PYR-GCK          AAERYTRRHGHRPKNDYGSSLFAVSAADGLRWARSTGALAAAFPRYHPRW
Mvan_0241|M.vanbaalenii_PYR-1       AAEMYTRRHGHRPKNDYGSSLFAVHARDGLRWAQGTGALLAAFPRYHPRW
MAB_4481|M.abscessus_ATCC_1997      AARWYTRKHGHPPKNNYGSSLFPVSVRDGLRWARDTGTLTAAFPRYHPKW
MSMEG_3286|M.smegmatis_MC2_155      SRGWNVRYWLAPLERTCSELRDAGFLIEELREPRPTEEAARRDPQAYQRL
                                    :    .*      :.  ..        : *  .  *       *: : : 

Mb0229c|M.bovis_AF2122/97           AWWLTSVPVLREFLVSNLVLVLTP-----
Rv0224c|M.tuberculosis_H37Rv        AWWLTSVPVLREFLVSNLVLVLTP-----
MLBr_02584|M.leprae_Br4923          AWWLTSVPVLREFVVSNLVLVLRPR----
MMAR_0473|M.marinum_M               AWWMTSVPMLREFLVSNLVLVLSPR----
MUL_1123|M.ulcerans_Agy99           AWWMTSVPMLREFLVSNLVLVLSPR----
MAV_4945|M.avium_104                AWWLTSVPVLREFLVSNLVLVLQPQ----
TH_2028|M.thermoresistible__bu      GWWLTRAPVVREFLVSNLVLVLSPPEIVN
Mflv_0427|M.gilvum_PYR-GCK          AWGLTRVPGVREFLVSNLVLVLRPT----
Mvan_0241|M.vanbaalenii_PYR-1       AWGLTKVPGLREFLVSNLVLVLRPC----
MAB_4481|M.abscessus_ATCC_1997      AWWITKIPALREVLVSNLVLVLRPR----
MSMEG_3286|M.smegmatis_MC2_155      AQAPEGFMTIRAVPDFRLRRPAAGR----
                                    .        :* .   .*

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2028		-	100% (273)	POSSIBLE METHYLTRANSFERASE (METHYLASE)
M. thermoresistible (build 8)	TH_2193	-	8e-09	37.50% (104)	CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)	TH_0087	-	4e-08	28.45% (116)	methyltransferase type 11