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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_1936 | - | 100% (339) | MCE-FAMILY PROTEIN MCE4B | |
M. thermoresistible (build 8) | TH_1734 | - | e-101 | 64.68% (269) | MCE-FAMILY PROTEIN MCE4B |
M. thermoresistible (build 8) | TH_4449 | - | 5e-78 | 44.05% (336) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3528c | mce4B | 1e-133 | 68.36% (335) | MCE-family protein MCE4B |
M. gilvum PYR-GCK | Mflv_1557 | - | 1e-145 | 73.08% (338) | virulence factor Mce family protein |
M. tuberculosis H37Rv | Rv3498c | mce4B | 1e-133 | 68.36% (335) | MCE-family protein MCE4B |
M. leprae Br4923 | MLBr_02590 | mce1B | 1e-54 | 35.33% (317) | putative secreted protein |
M. abscessus ATCC 19977 | MAB_4152c | - | 1e-128 | 66.17% (334) | MCE-family protein |
M. marinum M | MMAR_4986 | mce4B | 1e-132 | 67.76% (335) | MCE-family protein Mce4B |
M. avium 104 | MAV_0658 | - | 1e-133 | 69.85% (335) | virulence factor Mce family protein |
M. smegmatis MC2 155 | MSMEG_5899 | - | 1e-151 | 75.74% (338) | virulence factor Mce family protein |
M. ulcerans Agy99 | MUL_4061 | mce4B | 1e-131 | 67.16% (335) | MCE-family protein Mce4B |
M. vanbaalenii PYR-1 | Mvan_5201 | - | 1e-144 | 75.00% (336) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb3528c|M.bovis_AF2122/97 MAGSGVPSHRSMVIKVSVFAVVMLLVAAGLVVVFGDFRFGPTTVYHATFT Rv3498c|M.tuberculosis_H37Rv MAGSGVPSHRSMVIKVSVFAVVMLLVAAGLVVVFGDFRFGPTTVYHATFT MMAR_4986|M.marinum_M MASGGMPSHRSMVIKVSVFGVVMLVVAAALVVVFGDFRFGPTNVYHATFT MUL_4061|M.ulcerans_Agy99 MASGGMPSHRSMVIKVSVFGVVMLVLAAALVVVFGDFRFGPTNVYHATFT MAV_0658|M.avium_104 MAGSGMPSHRSMVIKVSIFAAAMLLVSAGLVVVFGDFRFGPESTYHATFV Mflv_1557|M.gilvum_PYR-GCK -----MNRERRTLVSVSIFTVVMLMVAASLIVVFGEFRFAAEDKYRATFT Mvan_5201|M.vanbaalenii_PYR-1 -----MR--DKTLINVGVFTVAMLLVAAMLVVVFGEFRFASEDKYHATFT MSMEG_5899|M.smegmatis_MC2_155 -----MHR-DRTMLKVGIFTMVMLLVAAGLVVVFGEFRFAAGQSYHATFS TH_1936|M.thermoresistible__bu ------------MIKVVVFTIAMVLVAAGLVVVFGEFRFASGRTYHATFT MAB_4152c|M.abscessus_ATCC_199 -----MKR--ATQIKVIVFTVVMLLVAAGLIITFGEFRFGSGKRYHAMFS MLBr_02590|M.leprae_Br4923 ------MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRTNGYTAEFT : : :* .:::.:. :::.**::**. * * * Mb3528c|M.bovis_AF2122/97 DASRLKAGQKVRIAGVPVGSVKAVKLNPDHS-IDVAFAIDRSYTLYSSTR Rv3498c|M.tuberculosis_H37Rv DASRLKAGQKVRIAGVPVGSVKAVKLNPDHS-IDVAFAIDRSYTLYSSTR MMAR_4986|M.marinum_M NASRLKAGQKVRIAGVPVGSVKAVDLNPDNT-IDVAFAIDRAYTMYSSTR MUL_4061|M.ulcerans_Agy99 NASRLKAGQKVRIAGVPVGSVKAVDLNPDNT-IDVAFAIDRAYTMYSSTR MAV_0658|M.avium_104 DVSRLKAGQKVRIAGVPVGAVEAVKLNRDNT-IDVTFGVDKRYTLYSSTR Mflv_1557|M.gilvum_PYR-GCK DASRLKTGQDVRIAGIPVGTVEGLSLNPDNS-VEVEFTVNERYQLYTSTK Mvan_5201|M.vanbaalenii_PYR-1 DASRLKAGQDVRIAGVPVGTVEGLTLNPDNT-VDVAFTVNDRYQLYTSTK MSMEG_5899|M.smegmatis_MC2_155 EASRLKAGQDVRIAGVPVGTVKSVKLNPDNT-VDVGFDVNKRYQLYTSSR TH_1936|M.thermoresistible__bu DASRLETGDDVRIAGVPVGTVKSVKLNEDNT-VDVSFDVNKRYQLYTSTR MAB_4152c|M.abscessus_ATCC_199 TASDLRSGQKVRIAGVPVGRVKNVSLNRDNS-VEVTFDVDSKYQLYSSSR MLBr_02590|M.leprae_Br4923 NISGLRTGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTT * *.:*: ** :*: ** *: : * . : : * * :: :* *: Mb3528c|M.bovis_AF2122/97 AVIRYENLVGDRFLEITSGPGE--LRKLPPGGTINVAHTQPALDLDALLG Rv3498c|M.tuberculosis_H37Rv AVIRYENLVGDRFLEITSGPGE--LRKLPPGGTINVAHTQPALDLDALLG MMAR_4986|M.marinum_M AVIRYENLVGDRYLEITSGPGE--LRKLPPGGTINAEHTQPALDLDALLG MUL_4061|M.ulcerans_Agy99 AVIRYENLVGDRYLEITSGPDE--LRKLPPGGTINAEHTQPALDLDALLG MAV_0658|M.avium_104 AVIRYENLVGDRYLEITSGPGE--LRKLPAGGTINSQHTQPALDLDALLG Mflv_1557|M.gilvum_PYR-GCK AVIRYENLVGDRYLEITSGPGD--LVKLPPGGTV--VNTEPALDLDALLG Mvan_5201|M.vanbaalenii_PYR-1 AVVRYENLVGDRYLEITSGPGD--LVKLPKGGTI--THTEPALDLDALLG MSMEG_5899|M.smegmatis_MC2_155 AVVRYENLVGDRYLEITSGPGE--LRKLAPGGTLGLQNTQPALDLDALLG TH_1936|M.thermoresistible__bu ALIRYENLVGDRYLEIASGPGE--LKKLPPGGRIPQTNTQPALDLDALLG MAB_4152c|M.abscessus_ATCC_199 AIIRYENLVGDRYLEITAGPGE--LHKLPDGGTLDKEHTQPALDLDALLG MLBr_02590|M.leprae_Br4923 AQIRYLDLIGNRYLELKHGEGQGSEKIMPAGGLIPLSRTSPALDLDALIG * :** :*:*:*:**: * .: :. ** : .*.********:* Mb3528c|M.bovis_AF2122/97 GLRPVLKGFDADKINTITSAVIELLQGQGGPLANVLADTGAFSAALGARD Rv3498c|M.tuberculosis_H37Rv GLRPVLKGFDADKINTITSAVIELLQGQGGPLANVLADTGAFSAALGARD MMAR_4986|M.marinum_M GLRPVLKGLDADKVNTVTGAVIELLQGQGGALANVLADTSAFSTALARRD MUL_4061|M.ulcerans_Agy99 GLRPVLKGLDADKVNTVTGAVIELLQGQGGALANVLADTSAFSTALARRD MAV_0658|M.avium_104 GLRPVLKGLDADKVNTISSAVIQLLQGQGGALSNVLADTSAFTSALGQRD Mflv_1557|M.gilvum_PYR-GCK GLKPVVKGLDGAKVNEISSAVIELLQGEGGALAAMLSSTSAFTQNLAARD Mvan_5201|M.vanbaalenii_PYR-1 GLKPVVKGLDGAKINEISNAVIELLQGEGGALSAMLSNTSAFTQNLAARD MSMEG_5899|M.smegmatis_MC2_155 GLRPVLKGLDGAKINEVSNAVIEMLQGQGGALANMLTSTSAFTQNLAARD TH_1936|M.thermoresistible__bu GLRPVLKGLEGHKVNEISTAVIQALQGQGGALSELLANTGSFTQRLADRY MAB_4152c|M.abscessus_ATCC_199 GLRPVLKGFDAAKVNEISNAFIQILQGQGGTLSQLLGDTSSFTSGLAERD MLBr_02590|M.leprae_Br4923 GFKPLFRALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERD *::*:.:.:: *:* :: *.: :**:**.: :* .*. :: :. * Mb3528c|M.bovis_AF2122/97 QLIGEVITNLNAVLATVDAKSAQFSASVDQLQQLVSGLAKNRDPIAGAIS Rv3498c|M.tuberculosis_H37Rv QLIGEVITNLNAVLATVDAKSAQFSASVDQLQQLVSGLAKNRDPIAGAIS MMAR_4986|M.marinum_M QLIGDTITNLNSVLATVDQRSAQFSASVDQLQQLITGLAENKDVIAGAIP MUL_4061|M.ulcerans_Agy99 QLIGDTITNLNSVLATVDQRSAQFSASVDQLQQLITGLAENKDVIAGAIP MAV_0658|M.avium_104 QLIGDVINNLNTVLTTVDQRSAQFSASVDQLQQLITGLAKHKDDIAGAIP Mflv_1557|M.gilvum_PYR-GCK QLIGDVITNLNTVLGTVDEKGAEFDASVDQLQKLITGLAEGRDPIAGAIG Mvan_5201|M.vanbaalenii_PYR-1 QLIGDVINNLNTVLGTVDEKGAEFNASVDQLQKLITGLAEGRDPIAGAIG MSMEG_5899|M.smegmatis_MC2_155 QLISDVIANLNTVLGTVDEKGAQFDASVDQLQQLITGLAENKDPIAGAIE TH_1936|M.thermoresistible__bu YVINDVITHLNAVVGTLDEKSAEFDASVDQLQQLITGLAEGRDPIAGALP MAB_4152c|M.abscessus_ATCC_199 QLIGDVINHLNEVLATVDSKSTQFSSSVDQLQQLISGLAQQRDVVAGALP MLBr_02590|M.leprae_Br4923 QAIGEVVKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFA *.:.: :** *: * : :*. :*::*: *::** . * :**:: Mb3528c|M.bovis_AF2122/97 PLASTTTDLTELLRNSRRPLQGILENARPLATELDNRKAEVNNDIEQLGE Rv3498c|M.tuberculosis_H37Rv PLASTTTDLTELLRNSRRPLQGILENARPLATELDNRKAEVNNDIEQLGE MMAR_4986|M.marinum_M PLASTTTDLTELLKNSRRPLQGLLENARPLATELDNRKDEVNNDVEQLGE MUL_4061|M.ulcerans_Agy99 PLASTTTDLTELLKNSRRPLQGLLENARPLATELDNRKDEVNNDVEQLGE MAV_0658|M.avium_104 PLASTTTDLTELLQNSRRPLQGVLENTRPLATELDNRKAEVNNDVEQLGE Mflv_1557|M.gilvum_PYR-GCK PLATAENDLTEMLETSRRPIQGVIENVRPFAQRMDERKADVNKVIEPLAE Mvan_5201|M.vanbaalenii_PYR-1 PLATAENDLTAMLEASRRPVQGVIENVRPFAQRMDERKGDVNKVIEPLAE MSMEG_5899|M.smegmatis_MC2_155 PLASAESDLTEMLEKSRRPVQGVIENVRPMAGRMDERKDDINKVIEPLAE TH_1936|M.thermoresistible__bu PLASAENDLTDMLRNGRRPVQGVLENLRPLATEIDNRKEEVNRVIEPLAE MAB_4152c|M.abscessus_ATCC_199 PLASTASSLESVLKDTRPYIKGTIEQARQLATRVDERKADVNVVVENLAE MLBr_02590|M.leprae_Br4923 HISNAAGTVANLLAEDHALLHKSINYLDGIQQPLIDQRLQLEDYLHKLPT ::.: : :* : :: :: : : ::: ::: :. * Mb3528c|M.bovis_AF2122/97 DYLRLS-ALGSYGAFFNIYFCSVTIKINGPAGSDILLPIGGQPDPSKGRC Rv3498c|M.tuberculosis_H37Rv DYLRLS-ALGSYGAFFNIYFCSVTIKINGPAGSDILLPIGGQPDPSKGRC MMAR_4986|M.marinum_M DYLRLA-ALGSYGAFFNIYFCTVTIKINGPAGSDILIPMGGQPDPSKGRC MUL_4061|M.ulcerans_Agy99 DYLRLA-ALGSYGAFFNIYFCTVTIKINGPAGSDILIPMGGQPDPSKGRC MAV_0658|M.avium_104 DYLRLA-ALGAYGSFFNIYFCSVTIKINGPAGSDILLPLGGQVDPSKGRC Mflv_1557|M.gilvum_PYR-GCK NYLRLN-ALGAYGSFFNIFYCSTRLKINGPAGSDILVPFGGPPDPSKGRC Mvan_5201|M.vanbaalenii_PYR-1 NYLRLN-ALGAYGSFFNIFYCSTRLKINGPAGSDILVPFGGPPDPSKGRC MSMEG_5899|M.smegmatis_MC2_155 NYLRLN-ALGAYGSFFNIFYCSVRLKVNGPAGSDILIPFGGPPDPSKGRC TH_1936|M.thermoresistible__bu NYLRLQ-SLGAYGAYFNIFYCSTRIKINGPAGSDILIPFGGPPDPSKGRC MAB_4152c|M.abscessus_ATCC_199 NYLRLN-ALGAYGSFFNIYYCSIRIKVNGPVGTDWLIPFGGPPDPSKGRC MLBr_02590|M.leprae_Br4923 VLNQIGRTIGSYGDFVNFYSCDITLKINGLQPGGPVRTVRLFQQP-TGRC :: ::*:** :.*:: * :*:** . : .. :* .*** Mb3528c|M.bovis_AF2122/97 AFAK- Rv3498c|M.tuberculosis_H37Rv AFAK- MMAR_4986|M.marinum_M AFAK- MUL_4061|M.ulcerans_Agy99 AFAK- MAV_0658|M.avium_104 AFVK- Mflv_1557|M.gilvum_PYR-GCK SEDG- Mvan_5201|M.vanbaalenii_PYR-1 AEVE- MSMEG_5899|M.smegmatis_MC2_155 SENG- TH_1936|M.thermoresistible__bu SEDG- MAB_4152c|M.abscessus_ATCC_199 AFKNE MLBr_02590|M.leprae_Br4923 TPQ-- :