For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_1936 ()

annotation: MCE-FAMILY PROTEIN MCE4B
coordinates: 3776319 - 3777335
length: 339

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1936-100% (339)MCE-FAMILY PROTEIN MCE4B
M. thermoresistible (build 8)TH_1734-e-10164.68% (269) MCE-FAMILY PROTEIN MCE4B
M. thermoresistible (build 8)TH_4449-5e-7844.05% (336) PUTATIVE virulence factor Mce family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3528cmce4B1e-13368.36% (335) MCE-family protein MCE4B
M. gilvum PYR-GCKMflv_1557-1e-14573.08% (338) virulence factor Mce family protein
M. tuberculosis H37RvRv3498cmce4B1e-13368.36% (335) MCE-family protein MCE4B
M. leprae Br4923MLBr_02590mce1B1e-5435.33% (317) putative secreted protein
M. abscessus ATCC 19977MAB_4152c-1e-12866.17% (334) MCE-family protein
M. marinum MMMAR_4986mce4B1e-13267.76% (335) MCE-family protein Mce4B
M. avium 104MAV_0658-1e-13369.85% (335) virulence factor Mce family protein
M. smegmatis MC2 155MSMEG_5899-1e-15175.74% (338) virulence factor Mce family protein
M. ulcerans Agy99MUL_4061mce4B1e-13167.16% (335) MCE-family protein Mce4B
M. vanbaalenii PYR-1Mvan_5201-1e-14475.00% (336) virulence factor Mce family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3528c|M.bovis_AF2122/97           MAGSGVPSHRSMVIKVSVFAVVMLLVAAGLVVVFGDFRFGPTTVYHATFT
Rv3498c|M.tuberculosis_H37Rv        MAGSGVPSHRSMVIKVSVFAVVMLLVAAGLVVVFGDFRFGPTTVYHATFT
MMAR_4986|M.marinum_M               MASGGMPSHRSMVIKVSVFGVVMLVVAAALVVVFGDFRFGPTNVYHATFT
MUL_4061|M.ulcerans_Agy99           MASGGMPSHRSMVIKVSVFGVVMLVLAAALVVVFGDFRFGPTNVYHATFT
MAV_0658|M.avium_104                MAGSGMPSHRSMVIKVSIFAAAMLLVSAGLVVVFGDFRFGPESTYHATFV
Mflv_1557|M.gilvum_PYR-GCK          -----MNRERRTLVSVSIFTVVMLMVAASLIVVFGEFRFAAEDKYRATFT
Mvan_5201|M.vanbaalenii_PYR-1       -----MR--DKTLINVGVFTVAMLLVAAMLVVVFGEFRFASEDKYHATFT
MSMEG_5899|M.smegmatis_MC2_155      -----MHR-DRTMLKVGIFTMVMLLVAAGLVVVFGEFRFAAGQSYHATFS
TH_1936|M.thermoresistible__bu      ------------MIKVVVFTIAMVLVAAGLVVVFGEFRFASGRTYHATFT
MAB_4152c|M.abscessus_ATCC_199      -----MKR--ATQIKVIVFTVVMLLVAAGLIITFGEFRFGSGKRYHAMFS
MLBr_02590|M.leprae_Br4923          ------MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRTNGYTAEFT
                                                 : : :*  .:::.:. :::.**::**.    * * * 

Mb3528c|M.bovis_AF2122/97           DASRLKAGQKVRIAGVPVGSVKAVKLNPDHS-IDVAFAIDRSYTLYSSTR
Rv3498c|M.tuberculosis_H37Rv        DASRLKAGQKVRIAGVPVGSVKAVKLNPDHS-IDVAFAIDRSYTLYSSTR
MMAR_4986|M.marinum_M               NASRLKAGQKVRIAGVPVGSVKAVDLNPDNT-IDVAFAIDRAYTMYSSTR
MUL_4061|M.ulcerans_Agy99           NASRLKAGQKVRIAGVPVGSVKAVDLNPDNT-IDVAFAIDRAYTMYSSTR
MAV_0658|M.avium_104                DVSRLKAGQKVRIAGVPVGAVEAVKLNRDNT-IDVTFGVDKRYTLYSSTR
Mflv_1557|M.gilvum_PYR-GCK          DASRLKTGQDVRIAGIPVGTVEGLSLNPDNS-VEVEFTVNERYQLYTSTK
Mvan_5201|M.vanbaalenii_PYR-1       DASRLKAGQDVRIAGVPVGTVEGLTLNPDNT-VDVAFTVNDRYQLYTSTK
MSMEG_5899|M.smegmatis_MC2_155      EASRLKAGQDVRIAGVPVGTVKSVKLNPDNT-VDVGFDVNKRYQLYTSSR
TH_1936|M.thermoresistible__bu      DASRLETGDDVRIAGVPVGTVKSVKLNEDNT-VDVSFDVNKRYQLYTSTR
MAB_4152c|M.abscessus_ATCC_199      TASDLRSGQKVRIAGVPVGRVKNVSLNRDNS-VEVTFDVDSKYQLYSSSR
MLBr_02590|M.leprae_Br4923          NISGLRTGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTT
                                      * *.:*: ** :*: ** *: : *  . : : * * ::    :* *: 

Mb3528c|M.bovis_AF2122/97           AVIRYENLVGDRFLEITSGPGE--LRKLPPGGTINVAHTQPALDLDALLG
Rv3498c|M.tuberculosis_H37Rv        AVIRYENLVGDRFLEITSGPGE--LRKLPPGGTINVAHTQPALDLDALLG
MMAR_4986|M.marinum_M               AVIRYENLVGDRYLEITSGPGE--LRKLPPGGTINAEHTQPALDLDALLG
MUL_4061|M.ulcerans_Agy99           AVIRYENLVGDRYLEITSGPDE--LRKLPPGGTINAEHTQPALDLDALLG
MAV_0658|M.avium_104                AVIRYENLVGDRYLEITSGPGE--LRKLPAGGTINSQHTQPALDLDALLG
Mflv_1557|M.gilvum_PYR-GCK          AVIRYENLVGDRYLEITSGPGD--LVKLPPGGTV--VNTEPALDLDALLG
Mvan_5201|M.vanbaalenii_PYR-1       AVVRYENLVGDRYLEITSGPGD--LVKLPKGGTI--THTEPALDLDALLG
MSMEG_5899|M.smegmatis_MC2_155      AVVRYENLVGDRYLEITSGPGE--LRKLAPGGTLGLQNTQPALDLDALLG
TH_1936|M.thermoresistible__bu      ALIRYENLVGDRYLEIASGPGE--LKKLPPGGRIPQTNTQPALDLDALLG
MAB_4152c|M.abscessus_ATCC_199      AIIRYENLVGDRYLEITAGPGE--LHKLPDGGTLDKEHTQPALDLDALLG
MLBr_02590|M.leprae_Br4923          AQIRYLDLIGNRYLELKHGEGQGSEKIMPAGGLIPLSRTSPALDLDALIG
                                    * :** :*:*:*:**:  * .:     :. ** :   .*.********:*

Mb3528c|M.bovis_AF2122/97           GLRPVLKGFDADKINTITSAVIELLQGQGGPLANVLADTGAFSAALGARD
Rv3498c|M.tuberculosis_H37Rv        GLRPVLKGFDADKINTITSAVIELLQGQGGPLANVLADTGAFSAALGARD
MMAR_4986|M.marinum_M               GLRPVLKGLDADKVNTVTGAVIELLQGQGGALANVLADTSAFSTALARRD
MUL_4061|M.ulcerans_Agy99           GLRPVLKGLDADKVNTVTGAVIELLQGQGGALANVLADTSAFSTALARRD
MAV_0658|M.avium_104                GLRPVLKGLDADKVNTISSAVIQLLQGQGGALSNVLADTSAFTSALGQRD
Mflv_1557|M.gilvum_PYR-GCK          GLKPVVKGLDGAKVNEISSAVIELLQGEGGALAAMLSSTSAFTQNLAARD
Mvan_5201|M.vanbaalenii_PYR-1       GLKPVVKGLDGAKINEISNAVIELLQGEGGALSAMLSNTSAFTQNLAARD
MSMEG_5899|M.smegmatis_MC2_155      GLRPVLKGLDGAKINEVSNAVIEMLQGQGGALANMLTSTSAFTQNLAARD
TH_1936|M.thermoresistible__bu      GLRPVLKGLEGHKVNEISTAVIQALQGQGGALSELLANTGSFTQRLADRY
MAB_4152c|M.abscessus_ATCC_199      GLRPVLKGFDAAKVNEISNAFIQILQGQGGTLSQLLGDTSSFTSGLAERD
MLBr_02590|M.leprae_Br4923          GFKPLFRALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERD
                                    *::*:.:.::  *:* :: *.:  :**:**.:  :* .*. ::  :. * 

Mb3528c|M.bovis_AF2122/97           QLIGEVITNLNAVLATVDAKSAQFSASVDQLQQLVSGLAKNRDPIAGAIS
Rv3498c|M.tuberculosis_H37Rv        QLIGEVITNLNAVLATVDAKSAQFSASVDQLQQLVSGLAKNRDPIAGAIS
MMAR_4986|M.marinum_M               QLIGDTITNLNSVLATVDQRSAQFSASVDQLQQLITGLAENKDVIAGAIP
MUL_4061|M.ulcerans_Agy99           QLIGDTITNLNSVLATVDQRSAQFSASVDQLQQLITGLAENKDVIAGAIP
MAV_0658|M.avium_104                QLIGDVINNLNTVLTTVDQRSAQFSASVDQLQQLITGLAKHKDDIAGAIP
Mflv_1557|M.gilvum_PYR-GCK          QLIGDVITNLNTVLGTVDEKGAEFDASVDQLQKLITGLAEGRDPIAGAIG
Mvan_5201|M.vanbaalenii_PYR-1       QLIGDVINNLNTVLGTVDEKGAEFNASVDQLQKLITGLAEGRDPIAGAIG
MSMEG_5899|M.smegmatis_MC2_155      QLISDVIANLNTVLGTVDEKGAQFDASVDQLQQLITGLAENKDPIAGAIE
TH_1936|M.thermoresistible__bu      YVINDVITHLNAVVGTLDEKSAEFDASVDQLQQLITGLAEGRDPIAGALP
MAB_4152c|M.abscessus_ATCC_199      QLIGDVINHLNEVLATVDSKSTQFSSSVDQLQQLISGLAQQRDVVAGALP
MLBr_02590|M.leprae_Br4923          QAIGEVVKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFA
                                      *.:.: :** *: *   :  :*. :*::*: *::** .  * :**:: 

Mb3528c|M.bovis_AF2122/97           PLASTTTDLTELLRNSRRPLQGILENARPLATELDNRKAEVNNDIEQLGE
Rv3498c|M.tuberculosis_H37Rv        PLASTTTDLTELLRNSRRPLQGILENARPLATELDNRKAEVNNDIEQLGE
MMAR_4986|M.marinum_M               PLASTTTDLTELLKNSRRPLQGLLENARPLATELDNRKDEVNNDVEQLGE
MUL_4061|M.ulcerans_Agy99           PLASTTTDLTELLKNSRRPLQGLLENARPLATELDNRKDEVNNDVEQLGE
MAV_0658|M.avium_104                PLASTTTDLTELLQNSRRPLQGVLENTRPLATELDNRKAEVNNDVEQLGE
Mflv_1557|M.gilvum_PYR-GCK          PLATAENDLTEMLETSRRPIQGVIENVRPFAQRMDERKADVNKVIEPLAE
Mvan_5201|M.vanbaalenii_PYR-1       PLATAENDLTAMLEASRRPVQGVIENVRPFAQRMDERKGDVNKVIEPLAE
MSMEG_5899|M.smegmatis_MC2_155      PLASAESDLTEMLEKSRRPVQGVIENVRPMAGRMDERKDDINKVIEPLAE
TH_1936|M.thermoresistible__bu      PLASAENDLTDMLRNGRRPVQGVLENLRPLATEIDNRKEEVNRVIEPLAE
MAB_4152c|M.abscessus_ATCC_199      PLASTASSLESVLKDTRPYIKGTIEQARQLATRVDERKADVNVVVENLAE
MLBr_02590|M.leprae_Br4923          HISNAAGTVANLLAEDHALLHKSINYLDGIQQPLIDQRLQLEDYLHKLPT
                                     ::.:   :  :*   :  ::  ::    :   : ::: :::  :. *  

Mb3528c|M.bovis_AF2122/97           DYLRLS-ALGSYGAFFNIYFCSVTIKINGPAGSDILLPIGGQPDPSKGRC
Rv3498c|M.tuberculosis_H37Rv        DYLRLS-ALGSYGAFFNIYFCSVTIKINGPAGSDILLPIGGQPDPSKGRC
MMAR_4986|M.marinum_M               DYLRLA-ALGSYGAFFNIYFCTVTIKINGPAGSDILIPMGGQPDPSKGRC
MUL_4061|M.ulcerans_Agy99           DYLRLA-ALGSYGAFFNIYFCTVTIKINGPAGSDILIPMGGQPDPSKGRC
MAV_0658|M.avium_104                DYLRLA-ALGAYGSFFNIYFCSVTIKINGPAGSDILLPLGGQVDPSKGRC
Mflv_1557|M.gilvum_PYR-GCK          NYLRLN-ALGAYGSFFNIFYCSTRLKINGPAGSDILVPFGGPPDPSKGRC
Mvan_5201|M.vanbaalenii_PYR-1       NYLRLN-ALGAYGSFFNIFYCSTRLKINGPAGSDILVPFGGPPDPSKGRC
MSMEG_5899|M.smegmatis_MC2_155      NYLRLN-ALGAYGSFFNIFYCSVRLKVNGPAGSDILIPFGGPPDPSKGRC
TH_1936|M.thermoresistible__bu      NYLRLQ-SLGAYGAYFNIFYCSTRIKINGPAGSDILIPFGGPPDPSKGRC
MAB_4152c|M.abscessus_ATCC_199      NYLRLN-ALGAYGSFFNIYYCSIRIKVNGPVGTDWLIPFGGPPDPSKGRC
MLBr_02590|M.leprae_Br4923          VLNQIGRTIGSYGDFVNFYSCDITLKINGLQPGGPVRTVRLFQQP-TGRC
                                       ::  ::*:** :.*:: *   :*:**    . : ..    :* .***

Mb3528c|M.bovis_AF2122/97           AFAK-
Rv3498c|M.tuberculosis_H37Rv        AFAK-
MMAR_4986|M.marinum_M               AFAK-
MUL_4061|M.ulcerans_Agy99           AFAK-
MAV_0658|M.avium_104                AFVK-
Mflv_1557|M.gilvum_PYR-GCK          SEDG-
Mvan_5201|M.vanbaalenii_PYR-1       AEVE-
MSMEG_5899|M.smegmatis_MC2_155      SENG-
TH_1936|M.thermoresistible__bu      SEDG-
MAB_4152c|M.abscessus_ATCC_199      AFKNE
MLBr_02590|M.leprae_Br4923          TPQ--
                                    :