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M. thermoresistible (build 8) TH_1776 ()

annotation: PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPB (PROTEIN-TYROSINE-PHOSPHATASE) (PTPase)
coordinates: 3480192 - 3480785
length: 198

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_1776 - 100% (198) PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPB (PROTEIN-TYROSINE-PHOSPHATASE) (PTPase)
M. thermoresistible (build 8) TH_2765 - 2e-15 36.30% (135) PUTATIVE putative protein tyrosine/serine phosphatase
M. thermoresistible (build 8) TH_3916 - 7e-14 33.89% (180) PUTATIVE -

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0158c ptbB 2e-55 52.63% (209) phosphotyrosine protein phosphatase PTPB
M. gilvum PYR-GCK Mflv_0735 - 3e-61 59.39% (197) protein tyrosine/serine phosphatase
M. tuberculosis H37Rv Rv0153c ptbB 1e-55 52.63% (209) phosphotyrosine protein phosphatase PTPB
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_4591 - 2e-30 38.58% (197) putative phosphotyrosine protein phosphatase
M. marinum M MMAR_0373 ptpB 6e-55 54.11% (207) phosphotyrosine protein phosphatase PtpB
M. avium 104 MAV_5145 - 3e-54 54.85% (206) phosphotyrosine protein phosphatase ptpb
M. smegmatis MC2 155 MSMEG_0100 - 5e-65 61.03% (195) phosphotyrosine protein phosphatase ptpb
M. ulcerans Agy99 MUL_4739 ptpB 3e-54 53.14% (207) phosphotyrosine protein phosphatase PtpB
M. vanbaalenii PYR-1 Mvan_0115 - 4e-63 61.42% (197) protein tyrosine/serine phosphatase

CLUSTAL 2.0.9 multiple sequence alignment


TH_1776|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0100|M.smegmatis_MC2_155      ------MTGPDGTSLELGGAWNFRDV--AQETG-IRPGVLYRSSELSKLS
Mflv_0735|M.gilvum_PYR-GCK          ---------MPFSGRELSGAWNFRDV--SEPAG-IAPGHLFRSSELSKLD
Mvan_0115|M.vanbaalenii_PYR-1       ---------MAAAGDELSGAWNFRDV--SEQTG-VAPGRFFRASELSKLD
Mb0158c|M.bovis_AF2122/97           ---------MAVR--ELPGAWNFRDV--ADTATALRPGRLFRSSELSRLD
Rv0153c|M.tuberculosis_H37Rv        ---------MAVR--ELPGAWNFRDV--ADTATALRPGRLFRSSELSRLD
MMAR_0373|M.marinum_M               ---------MAETGPELPGAWNFRDV--ADSTAALRPGRLFRSSELSGLD
MUL_4739|M.ulcerans_Agy99           ---------MAETGPELPGAWNFRDV--ADSTAALRPGRLFRSSELSGLD
MAV_5145|M.avium_104                ---------MPEALRELSGAWNFRDV--ADGAPMLRPGRLFRSGELSGLD
MAB_4591|M.abscessus_ATCC_1997      MTISSAESKASPADNPVEGIWNFRDVGGADSPVTIRPGVLFRSSELSGLT
                                                                                      

TH_1776|M.thermoresistible__bu      -------------------------------VPDDVVIHQLPFPDQSSVD
MSMEG_0100|M.smegmatis_MC2_155      DDGRAVFKRLGITDVADLRSHQEVQRRGPGQVPDGVAVHLLPFHPDDTSG
Mflv_0735|M.gilvum_PYR-GCK          DDGRGALIGFGVTDVADLRTARELERHGPGRVPTEVEVHHLPFVETMAAD
Mvan_0115|M.vanbaalenii_PYR-1       DTGRAALKGLGVTDVADLRTSRELERHGPGLVPAGVEIHHLPFVETMAAD
Mb0158c|M.bovis_AF2122/97           DAGRATLRRLGITDVADLRSSREVARRGPGRVPDGIDVHLLPFPDLADDD
Rv0153c|M.tuberculosis_H37Rv        DAGRATLRRLGITDVADLRSSREVARRGPGRVPDGIDVHLLPFPDLADDD
MMAR_0373|M.marinum_M               DQGRAALRRFKITDVADLRSSREVARRGPGQVPAGVDVHLLPFPDLADDQ
MUL_4739|M.ulcerans_Agy99           DQGRAALRRFKITDVADLRSSREVARRGPGQVPAGVDVHLLPFPDLADDQ
MAV_5145|M.avium_104                DEGRATLRRLGITDVADLRAAREVARRGPGRVPDGVEVHLLPFPDLGEHE
MAB_4591|M.abscessus_ATCC_1997      PAGAQTLRAFGVTDLYDLRSPTEIARTGSDRVDGGIRVHEVPFATPAAGE
                                                                   *   : :* :**       

TH_1776|M.thermoresistible__bu      G----EAPHESAFRRMMS-------EQPADGDVSAAARRYMTSAYKEFPT
MSMEG_0100|M.smegmatis_MC2_155      Q----DAPHESTFQRVMS-------ESPDGEDVTESARRYMTEVYEEFPT
Mflv_0735|M.gilvum_PYR-GCK          G----ESPHEHAFQRMMT-------DKPDGEPIAEAAARYMSEEYGRIAT
Mvan_0115|M.vanbaalenii_PYR-1       G----ESPHEHAFQRMMT-------DKPDDEPVADAAARYMTEEYGRIAT
Mb0158c|M.bovis_AF2122/97           A--DDSAPHETAFKRLLTNGGSNGESGESSQSINDAATRYMTDEYRQFPT
Rv0153c|M.tuberculosis_H37Rv        A--DDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYMTDEYRQFPT
MMAR_0373|M.marinum_M               AGTDDNAPHETAFKRLLT----DGDAGESSEAIDQVAARYMADEYRQFPM
MUL_4739|M.ulcerans_Agy99           AGTDDNAPHETAFKGLLT----DGDAGESSEAIDQVAARYMADEYRQFPM
MAV_5145|M.avium_104                AGTDDQAPHEHAFQRLLT----GDGAEQSAESVDEAATRYMIDEYRQFPT
MAB_4591|M.abscessus_ATCC_1997      E----RAPHEIAYRQMMLES-----MTAGRGPDPASQVEFMLAEYRRFPE
                                          :*** ::: ::                     .:*   * .:. 

TH_1776|M.thermoresistible__bu      LRGARRAVQQVVSLLIDGRPVIAHCFAGKDRTGFTVATVLAAAGVDRDAV
MSMEG_0100|M.smegmatis_MC2_155      LPGAHNAVRQVVSLLAAGRPVIAHCFAGKDRTGFTVATVLDAAGVDRDDI
Mflv_0735|M.gilvum_PYR-GCK          APLAQRAVHRVVTLLGSGRSVLAHCFAGKDRTGFTVAVVLEAAGVDRDAI
Mvan_0115|M.vanbaalenii_PYR-1       APFARRAVHRVVNLLGSERAVLAHCFAGKDRTGFTIAVVLEAAGVDRDAI
Mb0158c|M.bovis_AF2122/97           RNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVI
Rv0153c|M.tuberculosis_H37Rv        RNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVI
MMAR_0373|M.marinum_M               RTGAQRAVHRVFTLLAAGRPVLTHCFAGKDRTGFVVATVLEAVGVDREVI
MUL_4739|M.ulcerans_Agy99           RTGAQRAVHRVFTLLAAGRPVLTHCFAGKDRTGFVVATVLEAVGVDREVI
MAV_5145|M.avium_104                RNGAQRALHRVISLLAAGRAVLTHCFAGKDRTGFVVATVLEAVGVDRDVI
MAB_4591|M.abscessus_ATCC_1997      LPGTLVALKAVVDQLSSGATALVHCAAGKDRTGLLVGLLLSSVGVDYADI
                                       :  *:: *.  *    ..:.** *******: :. :* :.*:*   :

TH_1776|M.thermoresistible__bu      MADYLRSNDAVPQLRGRILSWIRDR--YADTPELETLAEARLTDAVLGVE
MSMEG_0100|M.smegmatis_MC2_155      FADFLRSNEAITPLRNRIMDSVRAR--SGDEPEIITFAEARLTDEVLGVR
Mflv_0735|M.gilvum_PYR-GCK          MADYLRSNEAVPQLRESILETIRVR--AAEAPEIMEFAEARLTDSVLGVR
Mvan_0115|M.vanbaalenii_PYR-1       MADYLRSNVAVPRLRESILATVRER--AVDAPEIMELAEARLTDAVLGVR
Mb0158c|M.bovis_AF2122/97           VADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVR
Rv0153c|M.tuberculosis_H37Rv        VADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVR
MMAR_0373|M.marinum_M               LADYLRSNDAVPQLRDRISEMIRERTDVELTPEVVTFTKARLSDGVLGVR
MUL_4739|M.ulcerans_Agy99           LADYLRSNDAVPQLRDRVSEMIRERTDVELTPEVVTFTKARLSDGVLGVR
MAV_5145|M.avium_104                VADFLRSNDAAPALRAQISAMIAQRQDTELTPEVVTWTEARLSDGVLGVR
MAB_4591|M.abscessus_ATCC_1997      AADYLRSNAAIGAMRAHISAQMNAA-----EPELAQTMAAMLSDEVLGVR
                                     **:**** :   :*  :   :         **:     * *:* ****.

TH_1776|M.thermoresistible__bu      EDYLAISWRTIDEEFGSLSNFLSAADVSADDVARLRDVLLG
MSMEG_0100|M.smegmatis_MC2_155      EEYLAAAWKRLEEAYGSLSGFMTAAGISPEELTALRDALR-
Mflv_0735|M.gilvum_PYR-GCK          EDYLDVARRTLEAEFGSLRDYLESAGVTDEDLARLRRVLHG
Mvan_0115|M.vanbaalenii_PYR-1       EEYLDSARRTIDDQFGSLTGYLESADVTDEDIRRLRKVLLG
Mb0158c|M.bovis_AF2122/97           AEYLAAARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
Rv0153c|M.tuberculosis_H37Rv        AEYLAAARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
MMAR_0373|M.marinum_M               PEYLAAAWQTIDETFGSLDGYLADSGITEADRHQLRSALLG
MUL_4739|M.ulcerans_Agy99           PEYLAAAWQTIDETFGSLDGYLADSGITEADRHQLRSALLG
MAV_5145|M.avium_104                EEYLAAARQTIDEKFGSLQAYLRDAGVGEADVQRLRAALLA
MAB_4591|M.abscessus_ATCC_1997      EEYLDTGFRQVANVFGSPEAMLVAAGVDDDGLTALRAALT-
                                     :**  . : :   :**    :  :.:       :* .*

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_1776		-	100% (198)	PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPB (PROTEIN-TYROSINE-PHOSPHATASE) (PTPase)
M. thermoresistible (build 8)	TH_2765	-	2e-15	36.30% (135)	PUTATIVE putative protein tyrosine/serine phosphatase
M. thermoresistible (build 8)	TH_3916	-	7e-14	33.89% (180)	PUTATIVE -