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AAAGDELSGAWNFRDVSEQTGVAPGRFFRASELSKLDDTGRAALKGLGVTDVADLRTSRELERHGPGLVP AGVEIHHLPFVETMAADGESPHEHAFQRMMTDKPDDEPVADAAARYMTEEYGRIATAPFARRAVHRVVNL LGSERAVLAHCFAGKDRTGFTIAVVLEAAGVDRDAIMADYLRSNVAVPRLRESILATVRERAVDAPEIME LAEARLTDAVLGVREEYLDSARRTIDDQFGSLTGYLESADVTDEDIRRLRKVLLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0115 | - | - | 100% (266) | protein tyrosine/serine phosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0158c | ptbB | 2e-77 | 54.41% (272) | phosphotyrosine protein phosphatase PTPB |
| M. gilvum PYR-GCK | Mflv_0735 | - | 1e-121 | 80.83% (266) | protein tyrosine/serine phosphatase |
| M. tuberculosis H37Rv | Rv0153c | ptbB | 2e-77 | 54.41% (272) | phosphotyrosine protein phosphatase PTPB |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4591 | - | 1e-45 | 39.47% (266) | putative phosphotyrosine protein phosphatase |
| M. marinum M | MMAR_0373 | ptpB | 6e-77 | 55.07% (276) | phosphotyrosine protein phosphatase PtpB |
| M. avium 104 | MAV_5145 | - | 4e-78 | 56.51% (269) | phosphotyrosine protein phosphatase ptpb |
| M. smegmatis MC2 155 | MSMEG_0100 | - | 3e-80 | 55.81% (258) | phosphotyrosine protein phosphatase ptpb |
| M. thermoresistible (build 8) | TH_1776 | - | 4e-63 | 61.42% (197) | PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPB |
| M. ulcerans Agy99 | MUL_4739 | ptpB | 4e-76 | 54.35% (276) | phosphotyrosine protein phosphatase PtpB |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0158c|M.bovis_AF2122/97 ---------MAVR--ELPGAWNFRDV--ADTATALRPGRLFRSSELSRLD
Rv0153c|M.tuberculosis_H37Rv ---------MAVR--ELPGAWNFRDV--ADTATALRPGRLFRSSELSRLD
MMAR_0373|M.marinum_M ---------MAETGPELPGAWNFRDV--ADSTAALRPGRLFRSSELSGLD
MUL_4739|M.ulcerans_Agy99 ---------MAETGPELPGAWNFRDV--ADSTAALRPGRLFRSSELSGLD
MAV_5145|M.avium_104 ---------MPEALRELSGAWNFRDV--ADGAPMLRPGRLFRSGELSGLD
Mvan_0115|M.vanbaalenii_PYR-1 ---------MAAAGDELSGAWNFRDV--SEQTG-VAPGRFFRASELSKLD
Mflv_0735|M.gilvum_PYR-GCK ---------MPFSGRELSGAWNFRDV--SEPAG-IAPGHLFRSSELSKLD
MSMEG_0100|M.smegmatis_MC2_155 ------MTGPDGTSLELGGAWNFRDV--AQETG-IRPGVLYRSSELSKLS
TH_1776|M.thermoresistible__bu --------------------------------------------------
MAB_4591|M.abscessus_ATCC_1997 MTISSAESKASPADNPVEGIWNFRDVGGADSPVTIRPGVLFRSSELSGLT
Mb0158c|M.bovis_AF2122/97 DAGRATLRRLGITDVADLRSSREVARRGPGRVPDGIDVHLLPFPDLADDD
Rv0153c|M.tuberculosis_H37Rv DAGRATLRRLGITDVADLRSSREVARRGPGRVPDGIDVHLLPFPDLADDD
MMAR_0373|M.marinum_M DQGRAALRRFKITDVADLRSSREVARRGPGQVPAGVDVHLLPFPDLADDQ
MUL_4739|M.ulcerans_Agy99 DQGRAALRRFKITDVADLRSSREVARRGPGQVPAGVDVHLLPFPDLADDQ
MAV_5145|M.avium_104 DEGRATLRRLGITDVADLRAAREVARRGPGRVPDGVEVHLLPFPDLGEHE
Mvan_0115|M.vanbaalenii_PYR-1 DTGRAALKGLGVTDVADLRTSRELERHGPGLVPAGVEIHHLPFVETMAAD
Mflv_0735|M.gilvum_PYR-GCK DDGRGALIGFGVTDVADLRTARELERHGPGRVPTEVEVHHLPFVETMAAD
MSMEG_0100|M.smegmatis_MC2_155 DDGRAVFKRLGITDVADLRSHQEVQRRGPGQVPDGVAVHLLPFHPDDTSG
TH_1776|M.thermoresistible__bu -------------------------------VPDDVVIHQLPFPDQSSVD
MAB_4591|M.abscessus_ATCC_1997 PAGAQTLRAFGVTDLYDLRSPTEIARTGSDRVDGGIRVHEVPFATPAAGE
* : :* :**
Mb0158c|M.bovis_AF2122/97 A--DDSAPHETAFKRLLTNGGSNGESGESSQSINDAATRYMTDEYRQFPT
Rv0153c|M.tuberculosis_H37Rv A--DDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYMTDEYRQFPT
MMAR_0373|M.marinum_M AGTDDNAPHETAFKRLLT----DGDAGESSEAIDQVAARYMADEYRQFPM
MUL_4739|M.ulcerans_Agy99 AGTDDNAPHETAFKGLLT----DGDAGESSEAIDQVAARYMADEYRQFPM
MAV_5145|M.avium_104 AGTDDQAPHEHAFQRLLT----GDGAEQSAESVDEAATRYMIDEYRQFPT
Mvan_0115|M.vanbaalenii_PYR-1 G----ESPHEHAFQRMMT-------DKPDDEPVADAAARYMTEEYGRIAT
Mflv_0735|M.gilvum_PYR-GCK G----ESPHEHAFQRMMT-------DKPDGEPIAEAAARYMSEEYGRIAT
MSMEG_0100|M.smegmatis_MC2_155 Q----DAPHESTFQRVMS-------ESPDGEDVTESARRYMTEVYEEFPT
TH_1776|M.thermoresistible__bu G----EAPHESAFRRMMS-------EQPADGDVSAAARRYMTSAYKEFPT
MAB_4591|M.abscessus_ATCC_1997 E----RAPHEIAYRQMMLES-----MTAGRGPDPASQVEFMLAEYRRFPE
:*** ::: :: .:* * .:.
Mb0158c|M.bovis_AF2122/97 RNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVI
Rv0153c|M.tuberculosis_H37Rv RNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVI
MMAR_0373|M.marinum_M RTGAQRAVHRVFTLLAAGRPVLTHCFAGKDRTGFVVATVLEAVGVDREVI
MUL_4739|M.ulcerans_Agy99 RTGAQRAVHRVFTLLAAGRPVLTHCFAGKDRTGFVVATVLEAVGVDREVI
MAV_5145|M.avium_104 RNGAQRALHRVISLLAAGRAVLTHCFAGKDRTGFVVATVLEAVGVDRDVI
Mvan_0115|M.vanbaalenii_PYR-1 APFARRAVHRVVNLLGSERAVLAHCFAGKDRTGFTIAVVLEAAGVDRDAI
Mflv_0735|M.gilvum_PYR-GCK APLAQRAVHRVVTLLGSGRSVLAHCFAGKDRTGFTVAVVLEAAGVDRDAI
MSMEG_0100|M.smegmatis_MC2_155 LPGAHNAVRQVVSLLAAGRPVIAHCFAGKDRTGFTVATVLDAAGVDRDDI
TH_1776|M.thermoresistible__bu LRGARRAVQQVVSLLIDGRPVIAHCFAGKDRTGFTVATVLAAAGVDRDAV
MAB_4591|M.abscessus_ATCC_1997 LPGTLVALKAVVDQLSSGATALVHCAAGKDRTGLLVGLLLSSVGVDYADI
: *:: *. * ..:.** *******: :. :* :.*:* :
Mb0158c|M.bovis_AF2122/97 VADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVR
Rv0153c|M.tuberculosis_H37Rv VADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVR
MMAR_0373|M.marinum_M LADYLRSNDAVPQLRDRISEMIRERTDVELTPEVVTFTKARLSDGVLGVR
MUL_4739|M.ulcerans_Agy99 LADYLRSNDAVPQLRDRVSEMIRERTDVELTPEVVTFTKARLSDGVLGVR
MAV_5145|M.avium_104 VADFLRSNDAAPALRAQISAMIAQRQDTELTPEVVTWTEARLSDGVLGVR
Mvan_0115|M.vanbaalenii_PYR-1 MADYLRSNVAVPRLRESILATVRER--AVDAPEIMELAEARLTDAVLGVR
Mflv_0735|M.gilvum_PYR-GCK MADYLRSNEAVPQLRESILETIRVR--AAEAPEIMEFAEARLTDSVLGVR
MSMEG_0100|M.smegmatis_MC2_155 FADFLRSNEAITPLRNRIMDSVRAR--SGDEPEIITFAEARLTDEVLGVR
TH_1776|M.thermoresistible__bu MADYLRSNDAVPQLRGRILSWIRDR--YADTPELETLAEARLTDAVLGVE
MAB_4591|M.abscessus_ATCC_1997 AADYLRSNAAIGAMRAHISAQMNAA-----EPELAQTMAAMLSDEVLGVR
**:**** : :* : : **: * *:* ****.
Mb0158c|M.bovis_AF2122/97 AEYLAAARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
Rv0153c|M.tuberculosis_H37Rv AEYLAAARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
MMAR_0373|M.marinum_M PEYLAAAWQTIDETFGSLDGYLADSGITEADRHQLRSALLG
MUL_4739|M.ulcerans_Agy99 PEYLAAAWQTIDETFGSLDGYLADSGITEADRHQLRSALLG
MAV_5145|M.avium_104 EEYLAAARQTIDEKFGSLQAYLRDAGVGEADVQRLRAALLA
Mvan_0115|M.vanbaalenii_PYR-1 EEYLDSARRTIDDQFGSLTGYLESADVTDEDIRRLRKVLLG
Mflv_0735|M.gilvum_PYR-GCK EDYLDVARRTLEAEFGSLRDYLESAGVTDEDLARLRRVLHG
MSMEG_0100|M.smegmatis_MC2_155 EEYLAAAWKRLEEAYGSLSGFMTAAGISPEELTALRDALR-
TH_1776|M.thermoresistible__bu EDYLAISWRTIDEEFGSLSNFLSAADVSADDVARLRDVLLG
MAB_4591|M.abscessus_ATCC_1997 EEYLDTGFRQVANVFGSPEAMLVAAGVDDDGLTALRAALT-
:** . : : :** : :.: :* .*