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M. thermoresistible (build 8) TH_2765 (-)

annotation: putative protein tyrosine/serine phosphatase
coordinates: 4197322 - 4198089
length: 256

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2765--100% (256)putative protein tyrosine/serine phosphatase
M. thermoresistible (build 8)TH_3916-2e-4641.77% (249) PUTATIVE -
M. thermoresistible (build 8)TH_4093-2e-4142.02% (257) PUTATIVE -

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0158cptbB1e-2030.07% (276) phosphotyrosine protein phosphatase PTPB
M. gilvum PYR-GCKMflv_0735-1e-2333.73% (249) protein tyrosine/serine phosphatase
M. tuberculosis H37RvRv0153cptbB9e-2130.80% (276) phosphotyrosine protein phosphatase PTPB
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4591-5e-1530.28% (251) putative phosphotyrosine protein phosphatase
M. marinum MMMAR_0373ptpB9e-2232.31% (260) phosphotyrosine protein phosphatase PtpB
M. avium 104MAV_5145-3e-1931.75% (274) phosphotyrosine protein phosphatase ptpb
M. smegmatis MC2 155MSMEG_0100-3e-2029.55% (247) phosphotyrosine protein phosphatase ptpb
M. ulcerans Agy99MUL_4739ptpB8e-2233.08% (260) phosphotyrosine protein phosphatase PtpB
M. vanbaalenii PYR-1Mvan_0115-3e-2132.27% (251) protein tyrosine/serine phosphatase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0158c|M.bovis_AF2122/97           ---------MAVR--ELPGAWNFRDV--ADTATALRPGRLFRSSELSRLD
Rv0153c|M.tuberculosis_H37Rv        ---------MAVR--ELPGAWNFRDV--ADTATALRPGRLFRSSELSRLD
MMAR_0373|M.marinum_M               ---------MAETGPELPGAWNFRDV--ADSTAALRPGRLFRSSELSGLD
MUL_4739|M.ulcerans_Agy99           ---------MAETGPELPGAWNFRDV--ADSTAALRPGRLFRSSELSGLD
MAV_5145|M.avium_104                ---------MPEALRELSGAWNFRDV--ADGAPMLRPGRLFRSGELSGLD
Mflv_0735|M.gilvum_PYR-GCK          ---------MPFSGRELSGAWNFRDV--SEPAG-IAPGHLFRSSELSKLD
Mvan_0115|M.vanbaalenii_PYR-1       ---------MAAAGDELSGAWNFRDV--SEQTG-VAPGRFFRASELSKLD
MSMEG_0100|M.smegmatis_MC2_155      ------MTGPDGTSLELGGAWNFRDV--AQETG-IRPGVLYRSSELSKLS
MAB_4591|M.abscessus_ATCC_1997      MTISSAESKASPADNPVEGIWNFRDVGGADSPVTIRPGVLFRSSELSGLT
TH_2765|M.thermoresistible__bu      ---------VSAPVTIVPNFRSLGGLP-TTDGRRVKEGVLYRSENLTNLD
                                                    : .  .: .:  :     :  * ::*: :*: * 

Mb0158c|M.bovis_AF2122/97           DAGRATLRRLGITDVADLRSSREVARR---GPGRVPDGIDVHLLPFPDLA
Rv0153c|M.tuberculosis_H37Rv        DAGRATLRRLGITDVADLRSSREVARR---GPGRVPDGIDVHLLPFPDLA
MMAR_0373|M.marinum_M               DQGRAALRRFKITDVADLRSSREVARR---GPGQVPAGVDVHLLPFPDLA
MUL_4739|M.ulcerans_Agy99           DQGRAALRRFKITDVADLRSSREVARR---GPGQVPAGVDVHLLPFPDLA
MAV_5145|M.avium_104                DEGRATLRRLGITDVADLRAAREVARR---GPGRVPDGVEVHLLPFPDLG
Mflv_0735|M.gilvum_PYR-GCK          DDGRGALIGFGVTDVADLRTARELERH---GPGRVPTEVEVHHLPFVETM
Mvan_0115|M.vanbaalenii_PYR-1       DTGRAALKGLGVTDVADLRTSRELERH---GPGLVPAGVEIHHLPFVETM
MSMEG_0100|M.smegmatis_MC2_155      DDGRAVFKRLGITDVADLRSHQEVQRR---GPGQVPDGVAVHLLPFHPDD
MAB_4591|M.abscessus_ATCC_1997      PAGAQTLRAFGVTDLYDLRSPTEIART---GSDRVDGGIRVHEVPFATPA
TH_2765|M.thermoresistible__bu      EDARKHLAALNIRSVCDLRSAGEQQKHPLVWPGENPKSIPVKTLPDARVA
                                      .   :  : : .: ***:  *  :     ..     : :: :*     

Mb0158c|M.bovis_AF2122/97           DDDA--DDSAPHETAFKRLLTNGGSNGESGESSQSINDAATRYMTDEYRQ
Rv0153c|M.tuberculosis_H37Rv        DDDA--DDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYMTDEYRQ
MMAR_0373|M.marinum_M               DDQAGTDDNAPHETAFKRLLT----DGDAGESSEAIDQVAARYMADEYRQ
MUL_4739|M.ulcerans_Agy99           DDQAGTDDNAPHETAFKGLLT----DGDAGESSEAIDQVAARYMADEYRQ
MAV_5145|M.avium_104                EHEAGTDDQAPHEHAFQRLLT----GDGAEQSAESVDEAATRYMIDEYRQ
Mflv_0735|M.gilvum_PYR-GCK          AADG----ESPHEHAFQRMMT-------DKPDGEPIAEAAARYMSEEYGR
Mvan_0115|M.vanbaalenii_PYR-1       AADG----ESPHEHAFQRMMT-------DKPDDEPVADAAARYMTEEYGR
MSMEG_0100|M.smegmatis_MC2_155      TSGQ----DAPHESTFQRVMS-------ESPDGEDVTESARRYMTEVYEE
MAB_4591|M.abscessus_ATCC_1997      AGEE----RAPHEIAYRQMMLES-----MTAGRGPDPASQVEFMLAEYRR
TH_2765|M.thermoresistible__bu      GTEL-----------IHELMS------------DPSGERLARLLRENAAD
                                                    : ::                     . :      

Mb0158c|M.bovis_AF2122/97           FPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDR
Rv0153c|M.tuberculosis_H37Rv        FPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDR
MMAR_0373|M.marinum_M               FPMRTGAQRAVHRVFTLLAAGRPVLTHCFAGKDRTGFVVATVLEAVGVDR
MUL_4739|M.ulcerans_Agy99           FPMRTGAQRAVHRVFTLLAAGRPVLTHCFAGKDRTGFVVATVLEAVGVDR
MAV_5145|M.avium_104                FPTRNGAQRALHRVISLLAAGRAVLTHCFAGKDRTGFVVATVLEAVGVDR
Mflv_0735|M.gilvum_PYR-GCK          IATAPLAQRAVHRVVTLLGSGRSVLAHCFAGKDRTGFTVAVVLEAAGVDR
Mvan_0115|M.vanbaalenii_PYR-1       IATAPFARRAVHRVVNLLGSERAVLAHCFAGKDRTGFTIAVVLEAAGVDR
MSMEG_0100|M.smegmatis_MC2_155      FPTLPGAHNAVRQVVSLLAAGRPVIAHCFAGKDRTGFTVATVLDAAGVDR
MAB_4591|M.abscessus_ATCC_1997      FPELPGTLVALKAVVDQLSSGATALVHCAAGKDRTGLLVGLLLSSVGVDY
TH_2765|M.thermoresistible__bu      MPTAFQDSMKAIFDAIIDDEALPMLVMCVAGKDRTGFVVAIILAALDVEW
                                    :.                    . :. * *******: :. :* : .:: 

Mb0158c|M.bovis_AF2122/97           DVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVL
Rv0153c|M.tuberculosis_H37Rv        DVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVL
MMAR_0373|M.marinum_M               EVILADYLRSNDAVPQLRDRISEMIRERTDVELTPEVVTFTKARLSDGVL
MUL_4739|M.ulcerans_Agy99           EVILADYLRSNDAVPQLRDRVSEMIRERTDVELTPEVVTFTKARLSDGVL
MAV_5145|M.avium_104                DVIVADFLRSNDAAPALRAQISAMIAQRQDTELTPEVVTWTEARLSDGVL
Mflv_0735|M.gilvum_PYR-GCK          DAIMADYLRSNEAVPQLRESILETIRVR--AAEAPEIMEFAEARLTDSVL
Mvan_0115|M.vanbaalenii_PYR-1       DAIMADYLRSNVAVPRLRESILATVRER--AVDAPEIMELAEARLTDAVL
MSMEG_0100|M.smegmatis_MC2_155      DDIFADFLRSNEAITPLRNRIMDSVRAR--SGDEPEIITFAEARLTDEVL
MAB_4591|M.abscessus_ATCC_1997      ADIAADYLRSNAAIGAMRAHISAQMNAA-----EPELAQTMAAMLSDEVL
TH_2765|M.thermoresistible__bu      DAIVADYLASKDHTDKYRLHQSLMEYIE-----EPPAELLSADTLLD--V
                                      * **:* *:      *                *         * *  :

Mb0158c|M.bovis_AF2122/97           GVRAEYLAAARQTIDETYGSLGGYLRDAG-ISQATVNRMRGVLLG
Rv0153c|M.tuberculosis_H37Rv        GVRAEYLAAARQTIDETYGSLGGYLRDAG-ISQATVNRMRGVLLG
MMAR_0373|M.marinum_M               GVRPEYLAAAWQTIDETFGSLDGYLADSG-ITEADRHQLRSALLG
MUL_4739|M.ulcerans_Agy99           GVRPEYLAAAWQTIDETFGSLDGYLADSG-ITEADRHQLRSALLG
MAV_5145|M.avium_104                GVREEYLAAARQTIDEKFGSLQAYLRDAG-VGEADVQRLRAALLA
Mflv_0735|M.gilvum_PYR-GCK          GVREDYLDVARRTLEAEFGSLRDYLESAG-VTDEDLARLRRVLHG
Mvan_0115|M.vanbaalenii_PYR-1       GVREEYLDSARRTIDDQFGSLTGYLESAD-VTDEDIRRLRKVLLG
MSMEG_0100|M.smegmatis_MC2_155      GVREEYLAAAWKRLEEAYGSLSGFMTAAG-ISPEELTALRDALR-
MAB_4591|M.abscessus_ATCC_1997      GVREEYLDTGFRQVANVFGSPEAMLVAAG-VDDDGLTALRAALT-
TH_2765|M.thermoresistible__bu      GNRAEYLKASFDTIDREHGSFENYLVEVCGLTPERRERLKELMLE
                                    * * :**  .   :   .**    :     :       ::  :