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M. thermoresistible (build 8) TH_1749 ()

annotation: POSSIBLE TRNA/RRNA METHYLTRANSFERASE
coordinates: 3369638 - 3370363
length: 242

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1749-100% (242)POSSIBLE TRNA/RRNA METHYLTRANSFERASE
M. thermoresistible (build 8)TH_1588tsnR4e-1229.87% (154) Possible 23S rRNA methyltransferase tsnR
M. thermoresistible (build 8)TH_1372-2e-1027.56% (225) POSSIBLE RRNA METHYLTRANSFERASE (RRNA METHYLASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3610c-1e-10681.74% (241) putative tRNA/rRNA methyltransferase
M. gilvum PYR-GCKMflv_1447-1e-11686.67% (240) RNA methyltransferase
M. tuberculosis H37RvRv3579c-1e-10782.16% (241) tRNA/rRNA methyltransferase
M. leprae Br4923MLBr_00324-1e-10480.42% (240) putative methyltransferase
M. abscessus ATCC 19977MAB_0572-1e-10982.08% (240) putative tRNA/rRNA methyltransferase
M. marinum MMMAR_5079-1e-10982.92% (240) tRNA/rRNA methyltransferase
M. avium 104MAV_0574-1e-11185.00% (240) RNA methyltransferase, TrmH family protein, group 3
M. smegmatis MC2 155MSMEG_6073-1e-11486.67% (240) RNA methyltransferase, TrmH family protein, group 3
M. ulcerans Agy99MUL_4155-1e-10982.92% (240) tRNA/rRNA methyltransferase
M. vanbaalenii PYR-1Mvan_5337-1e-11484.58% (240) RNA methyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1447|M.gilvum_PYR-GCK          MAGNSQRRGAVRKAGTKKGPQVGSGGVRRRGLEGRGATPPAHERPHHPAG
Mvan_5337|M.vanbaalenii_PYR-1       MAGNSQRRGAVRKAGTKKGPTVGSGGVRRRGLEGKGATPPAHQRPHHPAG
MSMEG_6073|M.smegmatis_MC2_155      MAGNSQRRGAVRKPGTKKGPTVGSGGVRRRGLEGRGATPPAHMRPNHPAA
Mb3610c|M.bovis_AF2122/97           MPGNSRRRGAVRKSGTKKGAGVGSGGQRRRGLEGRGPTPPAHLRPHHPAA
Rv3579c|M.tuberculosis_H37Rv        MPGNSRRRGAVRKSGTKKGAGVGSGGQRRRGLEGRGPTPPAHLRPHHPAA
MLBr_00324|M.leprae_Br4923          -------------------------------MEGRGPTPPAYLRPNHPAA
MAV_0574|M.avium_104                MAGNSRRRGAVRKAGTKKGPTVGSGGQRRRGLEGRGPTPPAHLRPNHPAA
MMAR_5079|M.marinum_M               MAGNSQRRGAIRKSGTKKGTSVGSGGQRRRGLEGRGPTPPAHMRPNHPAA
MUL_4155|M.ulcerans_Agy99           MAGNSQRRGAIRKSGTKKGTSVGSGGQRRRGLEGRGPTPSAHMRPNHPAA
TH_1749|M.thermoresistible__bu      --------------------------------------------------
MAB_0572|M.abscessus_ATCC_1997      MAGNSQRRGAVRKPGTKKGPTVGSGGVRRRGLEGKGATPPAEQRTKHPAA
                                                                                      

Mflv_1447|M.gilvum_PYR-GCK          KRAAKAARQAQGRH---KKTDDTEIVLGRNPVVECLRAGVPATALYVALG
Mvan_5337|M.vanbaalenii_PYR-1       KRAAKAARQAQGRH---KKTDDTEIVLGRNPVLECLRAGVPATALYVALG
MSMEG_6073|M.smegmatis_MC2_155      KKARAAAKAQQQRAG--RKADETELVLGRNPVLECLRAKVPATALYVALG
Mb3610c|M.bovis_AF2122/97           KRARAQPRR-PVK-----RADETETVLGRNPVLECLRAGVPATALYVALG
Rv3579c|M.tuberculosis_H37Rv        KRARAQPRR-PVK-----RADETETVLGRNPVLECLRAGVPATALYVALG
MLBr_00324|M.leprae_Br4923          KRNQSSPHR-PVK-----RTDETETVLGRNPVLECLRAGVPATALYVALG
MAV_0574|M.avium_104                KRAQSPPRR-PAK-----RTEETETVLGRNPVLECLRAGVPATALYVALG
MMAR_5079|M.marinum_M               KRAKAQQRR-PARG----RTDETETVLGRNPVLECLRAGVPSTALYVALG
MUL_4155|M.ulcerans_Agy99           KRAKAQQRR-PARG----RTDETETVLGRNPVLECLRAGVPSTALYVALG
TH_1749|M.thermoresistible__bu      -------------------------VLGRNPVVECLRAEVPATALYVALG
MAB_0572|M.abscessus_ATCC_1997      KRAAVQRKIADAKQRRLKQGDEAEMVLGRNPVLECLRTGVPATALYVAVG
                                                             *******:****: **:******:*

Mflv_1447|M.gilvum_PYR-GCK          TDADERLTESVQMAADRGISILEVQRHDLDRMAANGLHQGIALQVPPYAY
Mvan_5337|M.vanbaalenii_PYR-1       ADSDERLTESVQIAADKGIAILEVPRHDLDRIAANGMHQGIALQVPPYNY
MSMEG_6073|M.smegmatis_MC2_155      TDADERVTESVQIAADRGISILEVPRTDLDRMSNHGLHQGLGLQVPPYAY
Mb3610c|M.bovis_AF2122/97           TEADERLTECVARAADSGIAIVELLRADLDRMTANHLHQGIALQVPPYNY
Rv3579c|M.tuberculosis_H37Rv        TEADERLTECVARAADSGIAIVELLRADLDRMTANHLHQGIALQVPPYNY
MLBr_00324|M.leprae_Br4923          TEVDKRLTESVMRAADVGVAILEVPRTYLDRITNNHLHQGIALQVPPYHY
MAV_0574|M.avium_104                TEADERLTESVSRAADSGISILEVPRADLDRMTGNHLHQGIALQVPPYIY
MMAR_5079|M.marinum_M               VEADERLTESVSRAADSGIPILEVPRTDLDRMTANHLHQGIALQVPPYNY
MUL_4155|M.ulcerans_Agy99           VEADERLTESVSRAADSGIPILEVPRTDLDRMTANHLHQGIALQVPPYNY
TH_1749|M.thermoresistible__bu      TEADERLTEAVRLAADAGISILEVPRHDLDRISANGLHQGIALQVPPYQY
MAB_0572|M.abscessus_ATCC_1997      ADNDERLTESVALAADAGIAILEVPRPDLDRMSTNGLHQGLALQIPPYKY
                                    .: *:*:**.*  *** *:.*:*: *  ***:: : :***:.**:*** *

Mflv_1447|M.gilvum_PYR-GCK          AHPDDLLRDAKSDAAPALLVALDNISDPRNLGAIVRSVAAFGGHGVVLPQ
Mvan_5337|M.vanbaalenii_PYR-1       AHPDDLLAEAKSDAMPALLVALDNISDPRNLGAIVRSVAAFGGHGVLIPQ
MSMEG_6073|M.smegmatis_MC2_155      AHPDDLLATARADAAPALLVALDNISDPRNLGAIVRSVAAFAGHGVVIPQ
Mb3610c|M.bovis_AF2122/97           AHPDDLLA-AALDQPPALLVALDNLSDPRNLGAIMRSVAAFGGHGVLIPQ
Rv3579c|M.tuberculosis_H37Rv        AHPDDLLA-AALDQPPALLVALDNLSDPRNLGAIVRSVAAFGGHGVLIPQ
MLBr_00324|M.leprae_Br4923          VHSDDLLA-AATDSPPALLVALDNISDPRNLGAIVRSVAAFSGHGILIPQ
MAV_0574|M.avium_104                AHPDDLLE-AAAGSPPALLVALDNISDPRNLGAIVRSVAAFGGHGVLIPQ
MMAR_5079|M.marinum_M               AHPDDLLA-AALDTPPALLVALDNISDPRNLGAIVRSVAAFGGHGVLIPQ
MUL_4155|M.ulcerans_Agy99           AHPDDLLA-AALDTPPALLVALDNISDPRNLGAIVRSVAAFGGHGVLIPQ
TH_1749|M.thermoresistible__bu      AHPDDLLERATTDTEPALLVALDNISDPRNLGAIVRSVAAFAGHGVVIPQ
MAB_0572|M.abscessus_ATCC_1997      AHPDDLLARARAEAQPALLVALDNISDPRNLGAIVRSVAAFGGHGVVIPQ
                                    .*.****  *     *********:*********:******.***:::**

Mflv_1447|M.gilvum_PYR-GCK          RRSASVTAVAWRTSAGAAARTPVARATNLNRTLKQYADAGLQVVGLDAGG
Mvan_5337|M.vanbaalenii_PYR-1       RRSASVTAVAWRTSAGAAARTPVARATNLTRALKQWADAGLQVVGLDADG
MSMEG_6073|M.smegmatis_MC2_155      RRSASVTAVAWRTSAGAAARVPVARATNLNRTLKSFADAGLQIVGLDAGG
Mb3610c|M.bovis_AF2122/97           RRSASVTAVAWRTSAGAAARIPVARATNLTRTLKGWADRGVRVIGLDAGG
Rv3579c|M.tuberculosis_H37Rv        RRSASVTAVAWRTSAGAAARIPVARATNLTRTLKGWADRGVRVIGLDAGG
MLBr_00324|M.leprae_Br4923          RRSASVTAVAWRTSAGAAARIPVARATNLTRALKVWADQGLRVIGLDHDG
MAV_0574|M.avium_104                RRSASVTAVAWRTSAGAAARIPVARATNLTRTLQDWADRGLRVIGLDAGG
MMAR_5079|M.marinum_M               RRSASVTAVAWRTSAGAAARMPVARATNLTRALKDWADRGVRVVGLDAGG
MUL_4155|M.ulcerans_Agy99           RRSASVTAVAWRTSAGAAARMPVARATNLTRALKDWADRGVRVVGLDAGG
TH_1749|M.thermoresistible__bu      RRSASVTAVAWRTSAGAAARVPVARATNLNRTLKNWADAGLMIVGLDAGG
MAB_0572|M.abscessus_ATCC_1997      RRSASVTAVAWRTSAGAAARLPVARATNLTRTLKDWQDKGITIVGLDAGG
                                    ******************** ********.*:*: : * *: ::*** .*

Mflv_1447|M.gilvum_PYR-GCK          DTTIDEIDGLTPTIVVVGSEGKGLSRLVRENCDRIVSIPMAGPTESLNAS
Mvan_5337|M.vanbaalenii_PYR-1       DTTVDQIDGAGPIVVVVGSEGKGLSRLVRENCDAVVSIPMAGPTESLNAS
MSMEG_6073|M.smegmatis_MC2_155      DTTLDELDATGPTVVVVGSEGKGLSRLVREHCDAIVSIPMAGPTESLNAS
Mb3610c|M.bovis_AF2122/97           GTALDDVDGTDSLVVVVGSEGKGLSRLVRQNCDEVVSIPMAAQAESLNAS
Rv3579c|M.tuberculosis_H37Rv        GTALDDVDGTDSLVVVVGSEGKGLSRLVRQNCDEVVSIPMAAQAESLNAS
MLBr_00324|M.leprae_Br4923          DTALDDLDGTDPLAVVVGSEGKGLSRLVRHSCDEVVSIPMAGQVESLNAS
MAV_0574|M.avium_104                DTTLDDLDGSDPLVVVVGSEGKGLSRLVRQNCDEVVSIPMAGSAESLNAS
MMAR_5079|M.marinum_M               DTAIDDLDGSDPIVVVVGSEGKGLSRLVRQTCDEVVSVPMAGPTESLNAS
MUL_4155|M.ulcerans_Agy99           DTAIDDLDGSDPIVVVVGSEGKGLSRLVRQTCDEVVSVPMAGPTESLNAS
TH_1749|M.thermoresistible__bu      DTTLDELDGTTPLVVVVGSEGKGLSRLVRENCDLVVSIPMAGPAESLNAS
MAB_0572|M.abscessus_ATCC_1997      DTELDNLDGVGDIAVVVGSEGKGLSQLVRKTCDAVVSIPMAGPVESLNAS
                                    .* :*::*.     ***********:***. ** :**:***. .******

Mflv_1447|M.gilvum_PYR-GCK          VAAGVVLAEIARQRRLS---------------------------------
Mvan_5337|M.vanbaalenii_PYR-1       VAAGVVLAEIARQRRSA---------------------------------
MSMEG_6073|M.smegmatis_MC2_155      VAAGVVLAEIARQRRS----------------------------------
Mb3610c|M.bovis_AF2122/97           VAAGVVLAAIARQRRRPREPREQDAESHDLSSNHAILRLLAPLRLDPQNL
Rv3579c|M.tuberculosis_H37Rv        VAAGVVLAEIARQRRRPREPREQ-------TQNRMI--------------
MLBr_00324|M.leprae_Br4923          VAVGVVLAEIARQRRL----------------------------------
MAV_0574|M.avium_104                VAAGVVLAEISRQRRG----------------------------------
MMAR_5079|M.marinum_M               VAAGVVLAEIARQRRT----------------------------------
MUL_4155|M.ulcerans_Agy99           VAAGVVLAEIARQRRT----------------------------------
TH_1749|M.thermoresistible__bu      VAAGVVLADIARQRRR----------------------------------
MAB_0572|M.abscessus_ATCC_1997      VAAGVVLAEIARQRR-----------------------------------
                                    **.***** *:****                                   

Mflv_1447|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5337|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_6073|M.smegmatis_MC2_155      --------------------------------------------------
Mb3610c|M.bovis_AF2122/97           GAGPQREHRHRQGRRHGAQSQSGVLADAGVDVVPAQHAPPQQVRQRTGIG
Rv3579c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00324|M.leprae_Br4923          --------------------------------------------------
MAV_0574|M.avium_104                --------------------------------------------------
MMAR_5079|M.marinum_M               --------------------------------------------------
MUL_4155|M.ulcerans_Agy99           --------------------------------------------------
TH_1749|M.thermoresistible__bu      --------------------------------------------------
MAB_0572|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_1447|M.gilvum_PYR-GCK          ---------
Mvan_5337|M.vanbaalenii_PYR-1       ---------
MSMEG_6073|M.smegmatis_MC2_155      ---------
Mb3610c|M.bovis_AF2122/97           QVGSDVDPE
Rv3579c|M.tuberculosis_H37Rv        ---------
MLBr_00324|M.leprae_Br4923          ---------
MAV_0574|M.avium_104                ---------
MMAR_5079|M.marinum_M               ---------
MUL_4155|M.ulcerans_Agy99           ---------
TH_1749|M.thermoresistible__bu      ---------
MAB_0572|M.abscessus_ATCC_1997      ---------