For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_1372 ()

annotation: POSSIBLE RRNA METHYLTRANSFERASE (RRNA METHYLASE)
coordinates: 2603857 - 2604729
length: 291

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1372-100% (291)POSSIBLE RRNA METHYLTRANSFERASE (RRNA METHYLASE)
M. thermoresistible (build 8)TH_1588tsnR9e-1732.94% (170) Possible 23S rRNA methyltransferase tsnR
M. thermoresistible (build 8)TH_1749-3e-1027.56% (225) POSSIBLE TRNA/RRNA METHYLTRANSFERASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0905-1e-11173.98% (269) rRNA methyltransferase
M. gilvum PYR-GCKMflv_1715-1e-12181.89% (265) tRNA/rRNA methyltransferase (SpoU)
M. tuberculosis H37RvRv0881-1e-11173.98% (269) rRNA methyltransferase
M. leprae Br4923MLBr_01397tsnR1e-1729.00% (231) putative rRNA methyltransferase
M. abscessus ATCC 19977MAB_0881-1e-11175.85% (265) putative tRNA/rRNA methyltransferase
M. marinum MMMAR_4651-1e-11275.56% (266) rRNA methyltransferase
M. avium 104MAV_1009-1e-11475.72% (276) SpoU rRNA methylase family protein
M. smegmatis MC2 155MSMEG_5687-1e-11779.34% (271) 23s ribosomal RNA methyltransferase
M. ulcerans Agy99MUL_0269-1e-11175.09% (265) rRNA methyltransferase
M. vanbaalenii PYR-1Mvan_5036-1e-12682.66% (271) tRNA/rRNA methyltransferase (SpoU)

CLUSTAL 2.0.9 multiple sequence alignment


Mb0905|M.bovis_AF2122/97            --------------------------------------------------
Rv0881|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4651|M.marinum_M               --------------------------------------------------
MUL_0269|M.ulcerans_Agy99           --------------------------------------------------
MAV_1009|M.avium_104                MPDSDARLASDLSLAVMRLARQLRFRNPSSPVSLSQLSALAMLANEGPMT
MAB_0881|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_1715|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5036|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5687|M.smegmatis_MC2_155      --------------------------------------------------
TH_1372|M.thermoresistible__bu      --------------------------------------------------
MLBr_01397|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0905|M.bovis_AF2122/97            --------------------------------------------------
Rv0881|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4651|M.marinum_M               --------------------------------------------------
MUL_0269|M.ulcerans_Agy99           --------------------------------------------------
MAV_1009|M.avium_104                PGALAVRERVRPPSMTRVIASLAEMGLVDRTPHPVDGRQVLVSVSEAGAE
MAB_0881|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_1715|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5036|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5687|M.smegmatis_MC2_155      --------------------------------------------------
TH_1372|M.thermoresistible__bu      --------------------------------------------------
MLBr_01397|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0905|M.bovis_AF2122/97            ------------------------------------MTEGRCAQHPDGLD
Rv0881|M.tuberculosis_H37Rv         ------------------------------------MTEGRCAQHPDGLD
MMAR_4651|M.marinum_M               ------------------------------------MTA---HSHVRDVD
MUL_0269|M.ulcerans_Agy99           --------------------------------------------------
MAV_1009|M.avium_104                LVKANRRARQEWLAKRLVHAGRRRARNPAPRGRSDAGPGRRRPVNTDALD
MAB_0881|M.abscessus_ATCC_1997      ------------------------------------------------ML
Mflv_1715|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5036|M.vanbaalenii_PYR-1       -------------------------------------------MIANNVE
MSMEG_5687|M.smegmatis_MC2_155      ---------------------------------------------MSPLQ
TH_1372|M.thermoresistible__bu      ----------------------------VHTLSGPNPDDPDGPDVTDGPD
MLBr_01397|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0905|M.bovis_AF2122/97            VQDVCDPDDPRLDDFRDLNSIDRRPDLPTGKALVIAEGVLVVQRMLASRF
Rv0881|M.tuberculosis_H37Rv         VQDVCDPDDPRLDDFRDLNSIDRRPDLPTGKALVIAEGVLVVQRMLASRF
MMAR_4651|M.marinum_M               VRDVSDPDDPCLDDFRDLNSIDRRPDLPSGKGLVIAEGVLVVQRMLASRF
MUL_0269|M.ulcerans_Agy99           MRDVSDPDDPCLDDFRDLNSIDRRPDLPSGKGLVIAEGVLVVQRMLASRF
MAV_1009|M.avium_104                VRDVDDPDDPRLDDFRDLNSVDRRPDLPSGKGLVIAEGVLVVQRMLASRF
MAB_0881|M.abscessus_ATCC_1997      VIDVHDPADSRLDSFRDLNSVDRRPDLPSGKGLVIAEGVLVVQRMLASRF
Mflv_1715|M.gilvum_PYR-GCK          MVDITDPADPRLDPFRDLNSVDRRPDLPSGKGLVIAEGVLVVQRMLASRF
Mvan_5036|M.vanbaalenii_PYR-1       VVDVTDPADPRLDDFRDLNSVDRRPDLPSGKGLVIAEGVLVVQRMLASRF
MSMEG_5687|M.smegmatis_MC2_155      VIDIDDPADPRIDDFRDLNSVDRRPDLPTGKALVIAEGVLVVQRMLASRF
TH_1372|M.thermoresistible__bu      VTDITDPADPRVDDFRDLNSVDRRPDLPGGKGLVIAEGVLVVQRMLASRF
MLBr_01397|M.leprae_Br4923          --MLTERSARVVAAVKLHRQVARRR-----VRRFLAEGPNLVEAAIVSGL
                                       : :     :  .:  ..: **         .:***  :*:  :.* :

Mb0905|M.bovis_AF2122/97            TPLALFGTDRRLAELKDDLAG----VGAPYYRASADVMARVIGFHLNRGV
Rv0881|M.tuberculosis_H37Rv         TPLALFGTDRRLAELKDDLAG----VGAPYYRASADVMARVIGFHLNRGV
MMAR_4651|M.marinum_M               SPRALLGTDRRLLELKDDLAG----VGVPYYRVSPDVMAQVVGFHLNRGV
MUL_0269|M.ulcerans_Agy99           SPRALLGTDRRLLELKEDLAG----VGAPYYRVSPDVMAQVVGFHLNRGV
MAV_1009|M.avium_104                RPHALLGTERRLAELRDDLAG----VPVPYYRTSADVMARVVGFHLNRGV
MAB_0881|M.abscessus_ATCC_1997      RPLALLGTDRRLSELAADLEP----VDVPYYRASAEVMAEVVGFHLNRGV
Mflv_1715|M.gilvum_PYR-GCK          VPRALLGTDRRLTELGTDLDG----LAAPFYRATAEVMAEAIGFHLNRGV
Mvan_5036|M.vanbaalenii_PYR-1       VPRALLGTDRRLTELGTDLAG----LDAPFYRASAEVMADVVGFHLNRGV
MSMEG_5687|M.smegmatis_MC2_155      IPRALLGTDRRLGELAADLDRYPQYADVPFYRASAEVMAEAIGFHLNRGV
TH_1372|M.thermoresistible__bu      TPRAFLGTDRRLTELRADLAA----VDAPFYRADAEVMAEVVGFHLNRGV
MLBr_01397|M.leprae_Br4923          VR-DVFVTEVAAQRHATVLAT----LKCPVHPVSERAAKALSDTVTPTGL
                                        .: *:    .    *         * : .   .     .     *:

Mb0905|M.bovis_AF2122/97            LAAARRVPEPSVAQVVAGARTVAVLEGVNDHENLGSIFRNAAGLSVDAVV
Rv0881|M.tuberculosis_H37Rv         LAAAGRVPEPSVAQVVAGARTVAVLEGVNDHENLGSIFRNAAGLSVDAVV
MMAR_4651|M.marinum_M               LAAASRVVEPSVGQVVDGARTIAVLEGVNDHENLGSIFRNAAGLGVDAVI
MUL_0269|M.ulcerans_Agy99           LAAASRVVEPSVGQVVDGARTIAVLEGVNDHENLSSIFRNAAGLGVHAVI
MAV_1009|M.avium_104                LAAARRVPEPGVAELLAGSRTVAVLEGVNDHENLGAIFRNAAGLGVDAVI
MAB_0881|M.abscessus_ATCC_1997      LAASRRPEELPAADLLQTARTVAVLEGVNDHENLGSIFRNAAGMGVDAVL
Mflv_1715|M.gilvum_PYR-GCK          LASASRAPELTVAEVLDGARTVAVLEGVNDHENLGSVFRNAAGLGVDAVI
Mvan_5036|M.vanbaalenii_PYR-1       LASASRAPELTVPHVLDGARTVAVLEGVNDHENLGSVFRNAAGLGVDGVI
MSMEG_5687|M.smegmatis_MC2_155      LASAPRAAELTVDDVIADARTIAVLEGVNDHENLGSIFRNAAGLAVDAVI
TH_1372|M.thermoresistible__bu      LASAARPTELTVPQVLDGARTVAVLEGVNDHENLGSIFRNAAGLGVDAVI
MLBr_01397|M.leprae_Br4923          IAVCEMPTTRLATVLAGSPQLVVAAVEISEPGNAGTVIRIADAMGAAAVI
                                    :* .       .  :   .: :..   :.:  * .:::* * .:.. .*:

Mb0905|M.bovis_AF2122/97            FGTGCADPLYRRAVRVSMGHALLVPYARAADWPTELMTLKESGFRLLAMT
Rv0881|M.tuberculosis_H37Rv         FGTGCADPLYRRAVRVSMGHALLVPYARAADWPTELMTLKESGFRLLAMT
MMAR_4651|M.marinum_M               FGSGCADPLYRRAVRVSMGHALLVPYARATDWPAELVALKERGFRLLALT
MUL_0269|M.ulcerans_Agy99           FGSGCADPLYRRAVRVSMGHALLVPYARATDWPAELVALKERGFRLLALT
MAV_1009|M.avium_104                FGSGCADPLYRRAVRVSMGHALLVPYARATDWPAELKTLKEKGFRLLAMT
MAB_0881|M.abscessus_ATCC_1997      FGSGCADPLYRRAVRVSMGHALLVPFARLPEWPKSLYRLRDSGFRLLAMT
Mflv_1715|M.gilvum_PYR-GCK          FGSGCADPLYRRAVRVSMGHALLVPFARAANWPADLNILRDNDFRLLAMT
Mvan_5036|M.vanbaalenii_PYR-1       FGSGCADPLYRRAVRVSMGHALLVPFAKAANWPGDLELLRDQGFRLLAMT
MSMEG_5687|M.smegmatis_MC2_155      FGAGCADPLYRRAVRVSMGHALLVPFARASSWPTDLELLRDKGFRLLAMT
TH_1372|M.thermoresistible__bu      FGSGCADPLYRRAVRVSMGHALLVPYARARHWPADLRLLRDNGFQLLAMT
MLBr_01397|M.leprae_Br4923          FGGYTVDPYNGKCLRSSAGSIFSITVVVASDAYAAVTELRAAGLQVLATM
                                    **   .**   :.:* * *  : :. .        :  *:  .:::**  

Mb0905|M.bovis_AF2122/97            PHGNACKLPEAIAAVSHERIALLVGAEGPGLTAAALRISDVRVRIPMSRG
Rv0881|M.tuberculosis_H37Rv         PHGNACKLPEAIAAVSHERIALLVGAEGPGLTAAALRISDVRVRIPMSRG
MMAR_4651|M.marinum_M               PKGDARALPEAMDAVGDQPVALLVGAEGPGLTAAALRISDLRVRIPMSRG
MUL_0269|M.ulcerans_Agy99           PKGDARALPEAMDAVGDQPVALLVGAEGPGLTAAALRISDLRVRIPMSRG
MAV_1009|M.avium_104                PQGSACGLAEAMTAARGDRVAVLVGAEGPGLTPAALRLSDVRVRIPMSRG
MAB_0881|M.abscessus_ATCC_1997      PAGDSKALADAIPPLRAEKVALMVGAEGPGLTDVALRASDLRVRIPMANG
Mflv_1715|M.gilvum_PYR-GCK          PDPTVPTLADAVSGLTEERIAILVGAEGPGLKEHTMRSADVRVRIPMARG
Mvan_5036|M.vanbaalenii_PYR-1       PDPTVQTLAQAMSGLAEQRVAILVGAEGPGLKEHTMRASDVRVRIPMSRG
MSMEG_5687|M.smegmatis_MC2_155      PDPSAATLSDAMVQLEGDRVAILVGAEGPGLTERTMRASDVRVRIPMSRG
TH_1372|M.thermoresistible__bu      PNPKAETLAAVMPRLAAQKVAVLVGAEGPGLAESTMRAADVRVRIPMSRG
MLBr_01397|M.leprae_Br4923          VDG-ETSLDEAKPLLG-KPTAWLFGSEPHGLSTEIAEAADYRVRIPMVGG
                                           *  .      .  * :.*:*  **     . :* ******  *

Mb0905|M.bovis_AF2122/97            TDSLNVATAAALAFYERTR--SGHHIGPGT------
Rv0881|M.tuberculosis_H37Rv         TDSLNVATAAALAFYERTR--SGHHIGPGT------
MMAR_4651|M.marinum_M               TDSLNVATAAALAFYERAR--LGQ------------
MUL_0269|M.ulcerans_Agy99           TDSLNVATAAALAFYERAR--LGQ------------
MAV_1009|M.avium_104                TDSLNVATAAALAFYERSRPVGGHRAAAGGGDGQSG
MAB_0881|M.abscessus_ATCC_1997      TDSLNVATAAALAFYERAR--LAP------------
Mflv_1715|M.gilvum_PYR-GCK          TDSLNVATAAALAFYERDR--SHR------------
Mvan_5036|M.vanbaalenii_PYR-1       TDSLNVATAAALAFYERDR--LGR------------
MSMEG_5687|M.smegmatis_MC2_155      TDSLNVATAAALAFYERAR--LSH------------
TH_1372|M.thermoresistible__bu      TDSLNVATAAALAFYERSR--PSG------------
MLBr_01397|M.leprae_Br4923          VESLNVAATAAICLYQSSR--ALRL-----------
                                    .:*****::**:.:*:  *