For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_1741 | - | 100% (305) | 2-HYDROXY-6-OXO-6-PHENYLHEXA-2,4-DIENOATE HYDROLASE BPHD | |
| M. thermoresistible (build 8) | TH_3363 | - | 9e-63 | 43.15% (292) | PUTATIVE alpha/beta hydrolase fold |
| M. thermoresistible (build 8) | TH_4528 | - | 1e-25 | 30.29% (274) | PUTATIVE alpha/beta hydrolase fold |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3600c | bphD | 1e-133 | 77.97% (286) | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD |
| M. gilvum PYR-GCK | Mflv_1464 | - | 1e-146 | 84.07% (295) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv3569c | bphD | 1e-133 | 77.97% (286) | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD |
| M. leprae Br4923 | MLBr_01899 | lipG | 3e-05 | 25.17% (302) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_3810 | - | 5e-54 | 37.33% (292) | putative hydrolase, alpha/beta fold |
| M. marinum M | MMAR_5064 | bphD | 1e-131 | 79.86% (283) | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD |
| M. avium 104 | MAV_0592 | - | 1e-129 | 77.97% (286) | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase |
| M. smegmatis MC2 155 | MSMEG_6037 | - | 1e-140 | 84.15% (284) | 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase |
| M. ulcerans Agy99 | MUL_4140 | bphD | 1e-131 | 79.86% (283) | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD |
| M. vanbaalenii PYR-1 | Mvan_5307 | - | 1e-143 | 82.55% (298) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1464|M.gilvum_PYR-GCK MTSFAAEAAQQQEITFESTSRYAQVR---EDMRLHYHEAGV---GNPKTV
Mvan_5307|M.vanbaalenii_PYR-1 MTSFAAEAAQQQEITFESTSRFAQVR---EDMRLHYHEAGD---PESPTV
TH_1741|M.thermoresistible__bu MTSYIQEAENQVEITFESTSRYAEVKAGDRDMRLHYHEAGI---GHAQKV
MSMEG_6037|M.smegmatis_MC2_155 ------MVTATQEITFESTSRFADVQAGELAMRLHYHEAGD---PSAQTI
Mb3600c|M.bovis_AF2122/97 -------MTATEELTFESTSRFAEVDVD-GPLKLHYHEAGV---GNDQTV
Rv3569c|M.tuberculosis_H37Rv -------MTATEELTFESTSRFAEVDVD-GPLKLHYHEAGV---GNDQTV
MMAR_5064|M.marinum_M ---MTVTQSKTAEHTFESTSRYAEVDVD-GPLKLHYHEAGV---GNDQTV
MUL_4140|M.ulcerans_Agy99 ---MTVTQSKTAEHTFESTSRYAEVDVD-GPLKLHYHEAGV---GNDQTV
MAV_0592|M.avium_104 -------MTATEELTFESTSRFAEVDVD-GPLKLHYHEAGLSFKGTGRTV
MAB_3810|M.abscessus_ATCC_1997 -----------MDVTYEGTKRELATDEG----TLRYHEAGT--AGEGEPL
MLBr_01899|M.leprae_Br4923 ---------------MEVRSGYATSG----DLKLYYEDMGN---VDDPPV
* . * *.: * :
Mflv_1464|M.gilvum_PYR-GCK VLLHGGGPGASSWSN-FGRNIPVLAKHFHVLAVDQPGYGHSDKHTEHEQY
Mvan_5307|M.vanbaalenii_PYR-1 VLLHGGGPGASSWSN-FGKNIPVLAEHFHVLAVDQPGYGHSDKHTEHEQY
TH_1741|M.thermoresistible__bu VLLHGGGPGASSWSN-FGRNIAVLARHFHVIAVDQPGYGHSDKHTEHEQY
MSMEG_6037|M.smegmatis_MC2_155 VLLHGGGPGAASWSN-FGRNIAVLAEHFHVLAVDQPGYGLSDKHTEHEQY
Mb3600c|M.bovis_AF2122/97 VLLHGGGPGAASWTN-FSRNIAVLARHFHVLAVDQPGYGHSDKRAEHGQF
Rv3569c|M.tuberculosis_H37Rv VLLHGGGPGAASWTN-FSRNIAVLARHFHVLAVDQPGYGHSDKRAEHGQF
MMAR_5064|M.marinum_M VLLHGGGPGASSWSN-FARNIEVLAQQFHVLAVDQPGYGHSDKRAEHGQF
MUL_4140|M.ulcerans_Agy99 VLLHGGGPGASSWSN-FARNIEVLAQQFHVLAVDQPGYGHSDKRAEHGQF
MAV_0592|M.avium_104 VLLHGGGPGAASWTN-FGRNIPVLARHFHVLAVDQPGYGLSDKRAEHGQF
MAB_3810|M.abscessus_ATCC_1997 ILLHGSGPGVTGWRN-YRGNLGVFAKHFHTYVLEFPGFGVSDAVPGHPVL
MLBr_01899|M.leprae_Br4923 LLIMGLGAQLVLWRTAFCEKLVAQGLRVVRYDNRDVGLSSRTDSTEQPCP
:*: * *. * . : :: . . :. * . . :
Mflv_1464|M.gilvum_PYR-GCK NRYSATALL----------------------NLFDHLGIE-KAALVGNSL
Mvan_5307|M.vanbaalenii_PYR-1 NRYSATALL----------------------NLFDYLGIE-RAALVGNSL
TH_1741|M.thermoresistible__bu NRYSATALL----------------------ALFDHLGIE-RADLVGNSL
MSMEG_6037|M.smegmatis_MC2_155 NRYSAKAVR----------------------GLLDHLGVEGRVPLLGNSL
Mb3600c|M.bovis_AF2122/97 NRYAAMALK----------------------GLFDQLGLG-RVPLVGNSL
Rv3569c|M.tuberculosis_H37Rv NRYAAMALK----------------------GLFDQLGLG-RVPLVGNSL
MMAR_5064|M.marinum_M NHYAARALK----------------------ELFDQLGLG-RVPLVGNSL
MUL_4140|M.ulcerans_Agy99 NHYAARALK----------------------ELFDQLGLG-RVLLVGNSL
MAV_0592|M.avium_104 NRYAARALN----------------------GLFEQLELG-RVPLVGNSL
MAB_3810|M.abscessus_ATCC_1997 T--AGASVI----------------------RFMDGLGIS-SAAVVGNSM
MLBr_01899|M.leprae_Br4923 SQPLTARLIRFWLGQRNACAYTLEDMTDDAVALLDHLSIE-RAHIVGASM
. : ::: * : . ::* *:
Mflv_1464|M.gilvum_PYR-GCK GGGTAVRFALDNGKRAGKLVLMGPGGLSVNLFSPDPTEGVKLLGRFAAEP
Mvan_5307|M.vanbaalenii_PYR-1 GGGTAVRFALDNGKRAGKLVLMGPGGLSVNLFSPDPTEGVKLLGKFAAEP
TH_1741|M.thermoresistible__bu GGGTAVRFALDHPKRAGRLVLMGPGGLSVNMFAPDPTEGVKLLARFNAEP
MSMEG_6037|M.smegmatis_MC2_155 GGGTAVRFALDYPDRAGKLVLMGPGGLSVNLFAPDPTEGVKALAKFNVEP
Mb3600c|M.bovis_AF2122/97 GGGTAVRFALDYPARAGRLVLMGPGGLSINLFAPDPTEGVKRLSKFSVAP
Rv3569c|M.tuberculosis_H37Rv GGGTAVRFALDYPARAGRLVLMGPGGLSINLFAPDPTEGVKRLSKFSVAP
MMAR_5064|M.marinum_M GGGTAVRFALDYPDRAGRLVLMGPGGLSINLFAPDPTEGVKRLGKFSVAP
MUL_4140|M.ulcerans_Agy99 GGGTAVRFALDYPDRAGRLVLMGPGGLSINLFAPDPTEGVKRLGKFSVAP
MAV_0592|M.avium_104 GGGTAVRFALDYPDKAGRLVLMGPGGLSINLFAPDPTEGVKRLGKFSAEP
MAB_3810|M.abscessus_ATCC_1997 GGVVGINLAIKHPDRITKLVTIG--GVGPNIFSPSPSEGLRLLQEFTDNP
MLBr_01899|M.leprae_Br4923 GGMIAQIFAARFPTRTRSLAVFFSSNNRPFLPPPAPRALLALLTGPPTGS
** . :* : *. : . : .* * : * .
Mflv_1464|M.gilvum_PYR-GCK TRENIEKFLRIMVFDQAMITPELVEERFQIASTPESLAATKAMG--KSFA
Mvan_5307|M.vanbaalenii_PYR-1 TRENIEKFLRIMVFDQNMITPELVEERFQIASTPESLAATKAMG--KSFA
TH_1741|M.thermoresistible__bu TRENLEAFLRIMVYDQSLITEELIDERFAIAATPESLAATRAMG--KSFM
MSMEG_6037|M.smegmatis_MC2_155 TRENLEAFLRIMVFDQKLITPELVEERFAIASTPESLAATRAMG--KSFA
Mb3600c|M.bovis_AF2122/97 TRENLEAFLRVMVYDKNLITPELVDQRFALASTPESLTATRAMG--KSFA
Rv3569c|M.tuberculosis_H37Rv TRENLEAFLRVMVYDKNLITPELVDQRFALASTPESLTATRAMG--KSFA
MMAR_5064|M.marinum_M TRENLEAFLRVMVYDQKLITPELVDQRFELARTPESLAATRAMG--KSFA
MUL_4140|M.ulcerans_Agy99 TRENLEAFLRVMVYDQKLITPELVDQRFELARTPESLAATRAMG--KSFA
MAV_0592|M.avium_104 TRENLEAFLRVMVYDQKLITDELIDERFALASTPESLAATRAMG--MSFA
MAB_3810|M.abscessus_ATCC_1997 DRDKLIRWLNSMVWDPAVVTDELIEERWEAAINPDAHKTAQLMYGSKAFA
MLBr_01899|M.leprae_Br4923 RRDVVVDNVVRVTKITGSPLYRMPEEQVRTNAAEIYDRSFYPLGVSRQFS
*: : : :. .: ::: : : *
Mflv_1464|M.gilvum_PYR-GCK G-----ADFELGMMWRDVYKLRQRVLLIWGREDRVNPLDGALVALKQIPR
Mvan_5307|M.vanbaalenii_PYR-1 G-----ADFELGMMWRDVYKLRQRVLLIWGREDRVNPLDGALVALKQIPR
TH_1741|M.thermoresistible__bu G-----PDFELGMMWRDAYKLRQRVLLIWGREDRVNPLDGALVALKQIPR
MSMEG_6037|M.smegmatis_MC2_155 G-----ADFELGMMWREVYKLRQPVLLIWGREDRVNPLDGALVAVKQIPR
Mb3600c|M.bovis_AF2122/97 G-----ADFEAGMMWREVYRLRQPVLLIWGREDRVNPLDGALVALKTIPR
Rv3569c|M.tuberculosis_H37Rv G-----ADFEAGMMWREVYRLRQPVLLIWGREDRVNPLDGALVALKTIPR
MMAR_5064|M.marinum_M A-----ADFELGMMWREVYKLRQPVLLIWGREDRVNPLDGALVALKTIPR
MUL_4140|M.ulcerans_Agy99 A-----ADFELGMMWREVYKLRQPVLLIWGREDRVNPLDGALVALKTIPR
MAV_0592|M.avium_104 G-----ADFELGMMWREVHRLRQPVLLIWGREDRVNPLDGALVALKTIAR
MAB_3810|M.abscessus_ATCC_1997 MQQQFLANADIPPYWAMMHKIKCPTLLTWGRDDRVSPPDMAIVPMRLIPN
MLBr_01899|M.leprae_Br4923 A------ILGSGSLLHYNQRIIAPTVVIHGRADKLVRPSSGRAVARAITG
:: .:: ** *:: . . . : *.
Mflv_1464|M.gilvum_PYR-GCK VQLHVFGQCGHWAQLEKFDEFNKLTIDFLTN-------
Mvan_5307|M.vanbaalenii_PYR-1 VQLHVFGQCGHWAQLEKFDEFNKLTIDFLGGG------
TH_1741|M.thermoresistible__bu VQLHVFGQCGHWAQVEKFDEFNRLTIDFLEDGAKEAKS
MSMEG_6037|M.smegmatis_MC2_155 VQLHVFGQCGHWAQVEKFDEFNKLTIDFLGG-------
Mb3600c|M.bovis_AF2122/97 AQLHVFGQCGHWVQVEKFDEFNKLTIEFLGGGR-----
Rv3569c|M.tuberculosis_H37Rv AQLHVFGQCGHWVQVEKFDEFNKLTIEFLGGGR-----
MMAR_5064|M.marinum_M AQLHVFGQCGHWAQVEKFDEFNRLTIDFLGGAR-----
MUL_4140|M.ulcerans_Agy99 AQLHVFGQCGHWAQVEKFDEFNRLTIDFLGGAR-----
MAV_0592|M.avium_104 AQLHVFGQCGHWAQVEKFDEFNKLTIDFLGGA------
MAB_3810|M.abscessus_ATCC_1997 AELHIFPNSGHWVMIEAKQAFEQTVVDFLRR-------
MLBr_01899|M.leprae_Br4923 ARLVLFDGMGHDLPQQLWDQAVGVLMSNFAKAS-----
..* :* ** : : :. :