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M. thermoresistible (build 8) TH_2952 (-)

annotation: Alcohol dehydrogenase, zinc-binding domain protein
coordinates: 3477710 - 3478678
length: 323

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2952--100% (323)Alcohol dehydrogenase, zinc-binding domain protein
M. thermoresistible (build 8)TH_3116-2e-7149.21% (315) PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein
M. thermoresistible (build 8)TH_3212-7e-4035.81% (296) PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0154-1e-11364.40% (323) putative quinone oxidoreductase (NADPH:quinone oxidoreductase)
M. gilvum PYR-GCKMflv_0740-1e-12066.77% (322) alcohol dehydrogenase
M. tuberculosis H37RvRv0149-1e-11364.40% (323) quinone oxidoreductase
M. leprae Br4923MLBr_00118-2e-2727.56% (312) putative oxidireductase
M. abscessus ATCC 19977MAB_4603c-1e-11462.73% (322) oxidoreductase
M. marinum MMMAR_0361-1e-11667.18% (323) quinone oxidoreductase
M. avium 104MAV_4021-8e-7248.77% (324) oxidoreductase, zinc-binding dehydrogenase family protein
M. smegmatis MC2 155MSMEG_0097-1e-12971.74% (322) oxidoreductase, zinc-binding dehydrogenase family protein
M. ulcerans Agy99MUL_4758-1e-11666.56% (323) quinone oxidoreductase
M. vanbaalenii PYR-1Mvan_0107-1e-11968.63% (322) alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0740|M.gilvum_PYR-GCK          MKALVAQELTGPAGLAYTEVDEPN-GADAVVIDVGAAGVCFPDLLMLRGE
Mvan_0107|M.vanbaalenii_PYR-1       MKALVAQELTGPAGLAYTDVEDVH-GGDAVVLDVGAAGVCFPDLLMLRGE
MSMEG_0097|M.smegmatis_MC2_155      MKALVAQALTGTSGLAYADVDEPV-SGDAVIIDVGAAGVCFPDLLLLRGE
TH_2952|M.thermoresistible__bu      VKALVAQELSGPSGLVYTDWEDPSENDDVVVIDVRAAGLSFPDLLLIRGE
Mb0154|M.bovis_AF2122/97            MKACVVKELSGPSGMVYTDIDEVSGDGGKVVIDVRAAGVCFPDLLLTKGE
Rv0149|M.tuberculosis_H37Rv         MKACVVKELSGPSGMVYTDIDEVSGDGGKVVIDVRAAGVCFPDLLLTKGE
MMAR_0361|M.marinum_M               MKACVVQELSGPSGLVYTEVDDVSDGGGNVVIDVRAAGVCFPDLLLTKGE
MUL_4758|M.ulcerans_Agy99           MKACVVQELSGPSGLVYTEVDDVSDGGGNVVIDVRAAGVCLPDLLLTKGE
MAB_4603c|M.abscessus_ATCC_199      MKAIQAQSLSGPEGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGE
MAV_4021|M.avium_104                MRAARVTRLDGPDAIEVTDVDEPT--GDGVVVDVHAAGVAFPDALLTRGL
MLBr_00118|M.leprae_Br4923          MHAIVAESAN---QMVWREVPDVTAGPGEVLIEVAASGVNRADVLQVAGK
                                    ::*  .        :   :        . *:::* *:*:  .* *   * 

Mflv_0740|M.gilvum_PYR-GCK          YQMKVPAPFVPGLEVAGTVRSAPD-GSGFAAGQRVSGFSLLG-AWAERVA
Mvan_0107|M.vanbaalenii_PYR-1       YQMKVPAPFVPGLEVAGTVRSAPA-ESGFVAGQRVSAFSLLG-AWAEQVA
MSMEG_0097|M.smegmatis_MC2_155      YQMRLDPPFIPGMEVAGTVRSAPE-SSGFAPGQRVSAFTMIG-GYAEQVA
TH_2952|M.thermoresistible__bu      YQLRLDPPFIPGMEIAGEVRSAPQ-GSGFRPGQRVSAFSMMG-GFAERVA
Mb0154|M.bovis_AF2122/97            YQLKLTPPFVPGMETAGVVRSAPS-DAGFHVGERVSAFGVLG-GYAEQIA
Rv0149|M.tuberculosis_H37Rv         YQLKLTPPFVPGMETAGVVRSAPS-DAGFHVGERVSAFGVLG-GYAEQIA
MMAR_0361|M.marinum_M               YQLKLPPPFVPGLETAGVVRSAPA-RSGFRVGERVSAFGVLG-GYAEQVA
MUL_4758|M.ulcerans_Agy99           YQLKLPPPFVPGLETAGVVRSAPA-RSGFRVGERVSAFGVLG-GYAEQVA
MAB_4603c|M.abscessus_ATCC_199      YQLKMEPPFVPGIETAGVVRSAPE-GSGIKPGDRVMAFNFIG-GYAERVA
MAV_4021|M.avium_104                YQYRPELPFVLGAEIAGVVRSAPE-GAHVRSGDRVVGLTMLSGGMAEVAV
MLBr_00118|M.leprae_Br4923          YPHPPGASAIIGMEVAGVVAAVSSGVTEWSVGQEVCALLAGG-GYAEYVA
                                    *      . : * * ** * :..   :    *:.* .:   . . **  .

Mflv_0740|M.gilvum_PYR-GCK          LPVGSVVPTNAALDDGEAVCLLGNYYTMYFALHRRGALQPGETVLVLGSG
Mvan_0107|M.vanbaalenii_PYR-1       VPVGSVVPTNDALDDGSAVCLLGNYYTMHFALQRRGALQAGETVLVLGSG
MSMEG_0097|M.smegmatis_MC2_155      ALPDNVIPTPENLDDASAAALLGNYYTTQFALARRGALVPGETVLVLGSA
TH_2952|M.thermoresistible__bu      VAPQNVIPTADGIDDASAAALLGNYYTMYFALARRAALRPGETVLVFGSA
Mb0154|M.bovis_AF2122/97            VPVANVVRSPVELDDAGAVSLLVNYNTMYFALARRAALRPGDTVLVLGAA
Rv0149|M.tuberculosis_H37Rv         VPVANVVRSPVELDDAGAVSLLVNYNTMYFALARRAALRPGDTVLVLGAA
MMAR_0361|M.marinum_M               VPVSNVVRSPAELDDAEAVSLLVNYNTMYFALARRAAMRPGETVLVLGGA
MUL_4758|M.ulcerans_Agy99           VPVSNVVRSPAELDDAEAVSLLVNYNTMYFALARRAAMRPGETVLVLGGA
MAB_4603c|M.abscessus_ATCC_199      VAPSNILPTPPQLDDAEAVALIANYHTMYFAYARRGQLRAGETVLVLGAA
MAV_4021|M.avium_104                LAPDRVFKLPDNVSFEAGAGLLFNDLTVYFALTVRGRLQRGETVLVHGAA
MLBr_00118|M.leprae_Br4923          VPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLLLHGGT
                                         :.     :.   .. :     *        . :  *: :*: *. 

Mflv_0740|M.gilvum_PYR-GCK          GGIGTASIQIAKALGA-KVIAMVHRSSATDFVRSLGADVVLPLTDGWLDA
Mvan_0107|M.vanbaalenii_PYR-1       GGVGTASVQIAKALGA-RVIAMVHRPSAIEFVESLGADVVLPLTEGWLDA
MSMEG_0097|M.smegmatis_MC2_155      GGIGTASIQLAKAHGA-GVIAMVHRAGAEDFVSGLGADVVLPLTDGWRDA
TH_2952|M.thermoresistible__bu      GGVGTAAIQIAKAMGA-RVIAMVRRARGTEYVESLGPDVVLPLTEGWPQA
Mb0154|M.bovis_AF2122/97            GGVGTAAVQIAKAMQAGKVIAMVHREGAIDYVASLGADVVLPLTEGWAQQ
Rv0149|M.tuberculosis_H37Rv         GGVGTAAVQIAKAMQAGKVIAMVHREGAIDYVASLGADVVLPLTEGWAQQ
MMAR_0361|M.marinum_M               GGVGTAAIQIAKAMGAGQVIAVVHREGAIDYVASVGADVVLPLTEGWVDE
MUL_4758|M.ulcerans_Agy99           GGVGTAAIQIAKAMGAGQVIAVVHREGAIDYVASVGADVVLPLTEGWVEE
MAB_4603c|M.abscessus_ATCC_199      GGIGTAAIQIAKGMGA-KVIAVVNRTAATEFVKSVGADIVLPLEEGWAKA
MAV_4021|M.avium_104                GGIGTSALRLAPALGAARTIAVVSTTDKADIATAAGATDVV-LADGFKDA
MLBr_00118|M.leprae_Br4923          SGIGSHGIQVARALGA-KVAVTAGSEEKLEFCRALGAQITINYRDEDFVA
                                    .*:*: .:::* .  *  . . .      :   . *.  .:   :     

Mflv_0740|M.gilvum_PYR-GCK          VKAETGGRGVDLVVDPIGGPAFDDAVRALATEGRLLVIGFAAG-GIPTVK
Mvan_0107|M.vanbaalenii_PYR-1       VKAETGGRGVDLVVDPIGGPAFDDAIRALATEGRLLVIGFAAG-GIPTVK
MSMEG_0097|M.smegmatis_MC2_155      VLAATDGRGVDLVVDPIGGPAFDDAVRVLAPEGRLLVIGFAAGAGIPTVK
TH_2952|M.thermoresistible__bu      VRDATDGRGVDVVVDPVGGDVFDDAIRVLATEGRLLVLGFAAGQGIPTVK
Mb0154|M.bovis_AF2122/97            VRDHTYGQGVDIVVDPIGGPTFDDALGVLAIDGKLLLIGFAAG-AVPTLK
Rv0149|M.tuberculosis_H37Rv         VRDHTYGQGVDIVVDPIGGPTFDDALGVLAIDGKLLLIGFAAG-AVPTLK
MMAR_0361|M.marinum_M               VHKHTHGRGVDIVVDPIGGPVFDDAIRALAIDGKLLAIGFAAG-SIPTLA
MUL_4758|M.ulcerans_Agy99           VHKHTHGRGVDIVVDPIGGPVFDDAIHALAVDGKLLAIGFAAG-SIPTLA
MAB_4603c|M.abscessus_ATCC_199      VREATGGAGVDMVVDPIGGPAFDDAVRTLASEGRLLVVGFAAG-GIPTIK
MAV_4021|M.avium_104                VKELTHGRGVDIVVDPVGGDRFTDSLRSLAPGGRLLVVGFTGG-EIPTVK
MLBr_00118|M.leprae_Br4923          RLQQQNG-GADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGG-VKGELN
                                          * *.*:::* :*.  :   :  **  *:*: :*: .*     : 

Mflv_0740|M.gilvum_PYR-GCK          VNRLLLRNVSVVGVGWGEFVNRTPG----AQAEVGAALADLVDRG-LKPP
Mvan_0107|M.vanbaalenii_PYR-1       VNRLLLRNVSVVGVGWGEFVNRTPG----AQAQVGAALATLVDQG-LRPP
MSMEG_0097|M.smegmatis_MC2_155      VNRLLLRNVSVVGVGWGEFVRRNPG----AQAAVGAELGKLVADG-LRPP
TH_2952|M.thermoresistible__bu      VNRLLLRNVGVIGVGYGEFVARNPG----AQQLFGSGLRHLVEGG-LRPP
Mb0154|M.bovis_AF2122/97            VNRLLVRNISVVGVGWGEYLNAVPG----SAALFAWGLNQLVFLG-LRPP
Rv0149|M.tuberculosis_H37Rv         VNRLLVRNISVVGVGWGEYLNAVPG----SAALFAWGLNQLVFLG-LRPP
MMAR_0361|M.marinum_M               VNRLLRRNVGVLGVAWGEYLNRVPG----SVYLFSWGLNHLVSLG-LRPP
MUL_4758|M.ulcerans_Agy99           VNRLLRRNVGVLGVAWGEYLNRVPG----SVYLFSWGLNHLVSLG-LRPP
MAB_4603c|M.abscessus_ATCC_199      VNRLLLRNASLIGVAWGEFLRTHAD----YLYETQAGLEKLVAEG-MRPP
MAV_4021|M.avium_104                VNRLLLNNIDVVGVGWGAWTGTHPG----ALAEQWAGLERLLTSGELAPP
MLBr_00118|M.leprae_Br4923          LGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMIADGSVRPI
                                    :.::* ..  ::*          ..            :  ::  * : * 

Mflv_0740|M.gilvum_PYR-GCK          APVRYPLSDGVAALQAFADGAVNGKLVLEP-------------
Mvan_0107|M.vanbaalenii_PYR-1       EPVRFSLSDGVAALQAFADRAVNGKLVLEPDR-----------
MSMEG_0097|M.smegmatis_MC2_155      PPVRYRLADGAAALDAMAAGEVRGKLVLEP-------------
TH_2952|M.thermoresistible__bu      PPVRFPLSEGRAAFEALAAGEVLGKAVLEP-------------
Mb0154|M.bovis_AF2122/97            PPQRYPLSEAQAALQSLDDGGVLGKVVLEP-------------
Rv0149|M.tuberculosis_H37Rv         PPQRYPLSEAQAALQSLDDGGVLGKVVLEP-------------
MMAR_0361|M.marinum_M               PPQRFPLSEAQAALQSLADGAVLGKIVLEP-------------
MUL_4758|M.ulcerans_Agy99           PPQRFPLSEAQAALQSLAGGAVLGKIVLEP-------------
MAB_4603c|M.abscessus_ATCC_199      VSARIPLSEGRQALQDFADGKVYGKMVLVP-------------
MAV_4021|M.avium_104                EPVVYPLDEAAAAVASLENRTAKGKVVLRVRG-----------
MLBr_00118|M.leprae_Br4923          IGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH
                                          : :.  *   :    . ** **