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M. thermoresistible (build 8) TH_1643 (-)

annotation: NPL/P60-family protein secreted protein
coordinates: 3196859 - 3197833
length: 325

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1643--100% (325)NPL/P60-family protein secreted protein
M. thermoresistible (build 8)TH_3014-9e-1636.51% (126) PUTATIVE NLP/P60 family protein
M. thermoresistible (build 8)TH_0436-8e-1427.24% (312) Possible inv protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2213c-2e-1929.86% (278) hypothetical protein Mb2213c
M. gilvum PYR-GCKMflv_4838-9e-9360.96% (292) NLP/P60 protein
M. tuberculosis H37RvRv2190c-2e-1929.86% (278) hypothetical protein Rv2190c
M. leprae Br4923MLBr_00885-2e-1830.45% (266) putative secreted protein
M. abscessus ATCC 19977MAB_3664-6e-7043.59% (351) hypothetical protein MAB_3664
M. marinum MMMAR_3234-1e-1734.08% (179) hypothetical protein MMAR_3234
M. avium 104MAV_2304-4e-2230.63% (284) NLP/P60 family protein
M. smegmatis MC2 155MSMEG_1686-3e-9160.88% (294) NPL/P60-family protein secreted protein
M. ulcerans Agy99MUL_3545-9e-1932.52% (206) hypothetical protein MUL_3545
M. vanbaalenii PYR-1Mvan_1599-4e-9659.51% (326) NLP/P60 protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2213c|M.bovis_AF2122/97           -------------------MRLDQRWLIARVIMRSAIGFFASFTVSSGVL
Rv2190c|M.tuberculosis_H37Rv        -------------------MRLDQRWLIARVIMRSAIGFFASFTVSSGVL
MMAR_3234|M.marinum_M               -------------------MRLDCRQLTARVIRRSAIGSLASFTALSGFV
MUL_3545|M.ulcerans_Agy99           -------------------MRLDCRQLTARVIRRSAIGSLASFTALSGFV
MAV_2304|M.avium_104                --------------------------------------------------
MLBr_00885|M.leprae_Br4923          -------------------MRLGCKHPVVRLIAHFVVGTLVGFAVLSRFF
Mflv_4838|M.gilvum_PYR-GCK          -----------------------MPSATVEALAAPIRRVQGLVGPGWSGD
Mvan_1599|M.vanbaalenii_PYR-1       -----------------------MPSAIVTALAAPIRRVQALVGPGWSAD
MSMEG_1686|M.smegmatis_MC2_155      -----------------------MPGALVHALAAPLHDLRTLVGPGWVAT
TH_1643|M.thermoresistible__bu      --------------------------------------VRRWVWP-----
MAB_3664|M.abscessus_ATCC_1997      MVETSPISPSRLSEAVNTNYPDFSNNPFSSGLIGPAMDMAGTVGPGQFKE
                                                                                      

Mb2213c|M.bovis_AF2122/97           AANVLADPADDALAKLNELSRQAEQTTEALHSAQLDLNEKLAAQRAADQK
Rv2190c|M.tuberculosis_H37Rv        AANVLADPADDALAKLNELSRQAEQTTEALHSAQLDLNEKLAAQRAADQK
MMAR_3234|M.marinum_M               AAGAMADPAEDALAKLNELSRQAEQTTEAMHSAELDLGAKLAAQQAAENK
MUL_3545|M.ulcerans_Agy99           AAGAMADQAEDALAKLNELSRQAEQTTEAMHSAELELGAKLAAQQAAENK
MAV_2304|M.avium_104                ------------MAKLNELSRQAEQTTEAMHSAQLDLNEKLAAQRAAEKK
MLBr_00885|M.leprae_Br4923          VATAMADPAEDALAKLNELSRQAEQTTEAVHSAQLDLTEKLAAQRAADKK
Mflv_4838|M.gilvum_PYR-GCK          PAADPSGALAGVRQMLSDVAGSAGHAWRTVDDRWSGAGADAAASFASATT
Mvan_1599|M.vanbaalenii_PYR-1       PAADPAAALTGVRDTLTEVADAAGRAWRDAEAGWSGSGGDAAARFAAATS
MSMEG_1686|M.smegmatis_MC2_155      --DPPVAALSSVRSALTDLAAAAEASWARVSDGWAGTASDAAGEFSAVTA
TH_1643|M.thermoresistible__bu      -----------------------GIGSRPATDRRRRSSVXXXGRIAVA--
MAB_3664|M.abscessus_ATCC_1997      -GQDPSKMLESGMQVMQQVMQQGLQAGSSLIGSFAGAAAQALGQFAGMAG
                                                                              .  :    

Mb2213c|M.bovis_AF2122/97           LADNRTALDAARARLATFQTAVNKVAAATYMGGRTHGMDAILTAESPQLL
Rv2190c|M.tuberculosis_H37Rv        LADNRTALDAARARLATFQTAVNKVAAATYMGGRTHGMDAILTAESPQLL
MMAR_3234|M.marinum_M               LTDDQAALDAAKGQLASFQTAVNKVAAAAYMGGRANGMDTILTAPSPQLL
MUL_3545|M.ulcerans_Agy99           LTDDQAALDATKGQLASFQTAVNKVAAAAYMGGRANGMDTILTAPSPQLL
MAV_2304|M.avium_104                HDDDQAAVDAAKAHLASYQNAVNNLAAATYMGGRVDGMEAILTAGSPQGL
MLBr_00885|M.leprae_Br4923          YTDDQAALADAQVRLATFQAAVNKLAAATYMSGRINGMTALLTAYSPQQL
Mflv_4838|M.gilvum_PYR-GCK          AAIDDAADRAGRLGVAAEDAAAAVGHAHRRLQQIVDEFESKARALEQRLD
Mvan_1599|M.vanbaalenii_PYR-1       AAIDGAAARAGQLGVTAGDAAAAVAGAHRRLQSIVDEFEARAGALEPHLD
MSMEG_1686|M.smegmatis_MC2_155      ATARALADRAGMLSGVAREAGTAVARAQARLDAVIEAFEQRAAALEPRLD
TH_1643|M.thermoresistible__bu      -----LADAAARLAATTDTAAVAISDAAARLRVIIERFEARAGALEAHLD
MAB_3664|M.abscessus_ATCC_1997      QALSSMATRSGAMGANVGQASESTARATSLITEALQEFQHTSEALTPLLW
                                          *             .     *   :    . :     *      

Mb2213c|M.bovis_AF2122/97           IDRLSVQRVMAHQMSTQMARFKAAGEQAVKAEQAAAKSAADARSAAEQAA
Rv2190c|M.tuberculosis_H37Rv        IDRLSVQRVMAHQMSTQMARFKAAGEQAVKAEQAAAKSAADARSAAEQAA
MMAR_3234|M.marinum_M               IDGLSMQRVMAHQMATQMSGFRTAREQAAKAEQASEKSAADAKSAAEQAA
MUL_3545|M.ulcerans_Agy99           IDGLSMQRVMVHQMATQMSGFRTAREQTAKAEQASEKSAADAKSAAEQAA
MAV_2304|M.avium_104                IDKLAVQRLMATQMASQMKSYRIAGEQAAKAERESAKSAADAKSAAEQAA
MLBr_00885|M.leprae_Br4923          INKLALQRVLGVQMATQMAGYRDAGEQAVKAEQTSAKSAADAKHAADQAA
Mflv_4838|M.gilvum_PYR-GCK          DPGVARELLTAARDALGEAIAVVEELQTELDRQARIVDSAAPAGS-----
Mvan_1599|M.vanbaalenii_PYR-1       SPGVARELLAEARDALRRAVAVVEELLAELDGHTAAAGAVAPAGS-----
MSMEG_1686|M.smegmatis_MC2_155      EPGVAEELVAEAQRALREALAVIEELRAELDGHAGTVTSAPVA-------
TH_1643|M.thermoresistible__bu      EPGVAAELIAEARQALAEALGVVDDLHTDLARHATALTDPAGTPP-----
MAB_3664|M.abscessus_ATCC_1997      VPGVAAELAEAASRCTARVAEHTAQLEGELAGQAGELTGMAGADMGNPAT
                                       :: :       .                 :                 

Mb2213c|M.bovis_AF2122/97           AVRANLQHKQSQLQVQIAVVKSQYVALTPEERTALAD-------------
Rv2190c|M.tuberculosis_H37Rv        AVRANLQHKQSQLQVQIAVVKSQYVALTPEERTALAD-------------
MMAR_3234|M.marinum_M               AVRANLQHKQSQLQVQIAVVKSQYLALTPDQRTALAD-------------
MUL_3545|M.ulcerans_Agy99           AVRANLQHKQSQLQVQIAVVKSQYLALTPDQRTALVD-------------
MAV_2304|M.avium_104                AVRASLQSKQSQLQVQIAVVKSQYMSLTADQRTALAN-------------
MLBr_00885|M.leprae_Br4923          VVRAGLQSKQSKLQLQIAVVKSHYLSLSPRQRTTLAE-------------
Mflv_4838|M.gilvum_PYR-GCK          PP---------TTPAEWQSASGTGG-------------------------
Mvan_1599|M.vanbaalenii_PYR-1       PAVAPAGSPAVTAPAGWSGAGGAGP-------------------------
MSMEG_1686|M.smegmatis_MC2_155      ------------VPAGFSGAVPAMR-------------------------
TH_1643|M.thermoresistible__bu      SAR--------TVPSGFTGGSPPLGGMGSGLGGLPS--------------
MAB_3664|M.abscessus_ATCC_1997      PASGSVQPAMSAMQGGLQAGTQAMSGVASGVTQTMSSMGQGLGQIPQALT
                                                                                      

Mb2213c|M.bovis_AF2122/97           -----PGPVPAVAAIAPG-APPAALPPG-APPGDGPAP------------
Rv2190c|M.tuberculosis_H37Rv        -----PGPVPAVAAIAPG-APPAALPPG-APPGDGPAP------------
MMAR_3234|M.marinum_M               -----PGQVPAGLPGAPG-PAPEGTPPGGPPPAGAPVP------------
MUL_3545|M.ulcerans_Agy99           -----PGQVPAGLPGAPG-PAPEGTPPGGPPPAGAPVP------------
MAV_2304|M.avium_104                -----PGPAVPAAATAPGAPAPEAAPPG--TPPGGPGP------------
MLBr_00885|M.leprae_Br4923          -----PGPVPAVAT-LPG-----AASAGVSPPPD----------------
Mflv_4838|M.gilvum_PYR-GCK          ----GPGGGFAPGSGGFGNSGATGEMA-AFTRPDGT--------------
Mvan_1599|M.vanbaalenii_PYR-1       ----GPGGAPAGWAGPGAVNGGFGELA-GFTPVEAT--------------
MSMEG_1686|M.smegmatis_MC2_155      ----ASG---FSGLGPNLGSGSPSAFAPAFSAPEAAPG------------
TH_1643|M.thermoresistible__bu      ---VSPGGAAGSGLGGGAARGLAELVGLATDRPDSAA-------------
MAB_3664|M.abscessus_ATCC_1997      GLLSGAGGGSGSASALAGGSGLNGIAAGALANPFGAGGGHASSTAGGTSS
                                         .*                                           

Mb2213c|M.bovis_AF2122/97           -----------GVAPPP--GGMPGLPFVQPDGAGGD---RTAVVQAALTQ
Rv2190c|M.tuberculosis_H37Rv        -----------GVAPPP--GGMPGLPFVQPDGAGGD---RTAVVQAALTQ
MMAR_3234|M.marinum_M               -----------GEAPPP--GGVSAMPFTPPDGAGGD---RAAVVQAALTQ
MUL_3545|M.ulcerans_Agy99           -----------GEAPPPGAGGVSAMPFTPPDGAGGD---RAAVVQAALTQ
MAV_2304|M.avium_104                -----------GEAPPP--GGAPGMAPGGGGVGGGD---RATVVQAALTQ
MLBr_00885|M.leprae_Br4923          -------------AAPP--GGLLGVAP-APFAGGGD---RAAVVQAALTQ
Mflv_4838|M.gilvum_PYR-GCK          -----------DTPDAAEFGEGVAVRLPDGTVVVAPNAVAANAVRHALTQ
Mvan_1599|M.vanbaalenii_PYR-1       -----------GTPDAATFGDGVAVRLPDGTVVMAPNAVAASAVRHALTQ
MSMEG_1686|M.smegmatis_MC2_155      --------GLLDTPDAAMFGDGVAVRLPDGSTTMAPNAVAASAVRHALTQ
TH_1643|M.thermoresistible__bu      -----------RPADPAAFGVGVAVRLPDGSTVTAPNAVAADAVRHALTQ
MAB_3664|M.abscessus_ATCC_1997      GLGSANASAAKMLLDPRSMGKGVQLFLPDGSTSQAPNAAAAEAVRKALSQ
                                                   .   *    :         .     : .*: **:*

Mb2213c|M.bovis_AF2122/97           VGAPYAWGGAAPG-GFDCSGLVMWAFQQAGIALPHSSQALAHGGQPVALS
Rv2190c|M.tuberculosis_H37Rv        VGAPYAWGGAAPG-GFDCSGLVMWAFQQAGIALPHSSQALAHGGQPVALS
MMAR_3234|M.marinum_M               VGTPYAWGGAAPG-GFDCSGLVMWAFQQAGIALPHSSQALAHGGQPVSLS
MUL_3545|M.ulcerans_Agy99           VGTPYAWGGAAPG-GFDCSGLVMWAFQQAGIALPHSSQALAHEGQPVSLS
MAV_2304|M.avium_104                VGSPYVWGGAAPG-GFDCSGLVMWAFQQAGISLPHSSQALAHGGQPVSLS
MLBr_00885|M.leprae_Br4923          IGSPYAWGGAAPG-GFDCSGLVMWAYQQAGIALPHSSQALARGGQPVSLS
Mflv_4838|M.gilvum_PYR-GCK          LGVPYQWGGTTPGVGLDCSGLTQWAYREAGLDIPRLAQEQDIG-GAVSGG
Mvan_1599|M.vanbaalenii_PYR-1       LGVPYQWGGTTPGVGLDCSGLTQWAYREAGLSLPRLAQEQDLG-AAVGAG
MSMEG_1686|M.smegmatis_MC2_155      LGVPYHWGGTTPGVGLDCSGLTQWAYREAGLNIPRLAQEQDIG-AAVAAN
TH_1643|M.thermoresistible__bu      LGVPYQWGGTTPGVGLDCSGLTQWAYQQAGLQLPRLAQEQDVG-AAVDAG
MAB_3664|M.abscessus_ATCC_1997      VGVPYEWGGTKPGVGLDCSGLTQWAYGQSGVDIPRLAQEQGVG-VKVDQG
                                    :* ** ***: ** *:*****. **: ::*: :*: :*        *  .

Mb2213c|M.bovis_AF2122/97           DLQPGDVLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMDSSGPIYDA
Rv2190c|M.tuberculosis_H37Rv        DLQPGDVLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMDSSGPIYDA
MMAR_3234|M.marinum_M               DLQPGDVLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMNSSGPIYDA
MUL_3545|M.ulcerans_Agy99           DLQPGDVLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMNSSGPIYDA
MAV_2304|M.avium_104                DLQPGDVLTFYSDASHAGIYIGDGMMIHSSTYGVPVRVVPMNSSGPIYDA
MLBr_00885|M.leprae_Br4923          ELQPGDVLTFYSDASHAGIYVGDGMMIHSSTYGVPVRVVPMNSSGPIYDA
Mflv_4838|M.gilvum_PYR-GCK          SLLPGDLAVWDG---HVAMVVGDGLMVEA---GDPVQLSPIRTANAGQGF
Mvan_1599|M.vanbaalenii_PYR-1       SLLPGDLAVWDG---HVAMIVGDGTMIEA---GDPVKLSPIRTANAGQGF
MSMEG_1686|M.smegmatis_MC2_155      ALRPGDLAVWDG---HVAMIVGPNTMIEA---GDPVQLSPIRTTNAGQGF
TH_1643|M.thermoresistible__bu      ALLPGDLAVWDG---HVAMVVGNGMMIEA---GDPVKLSPIRTTNAGQGF
MAB_3664|M.abscessus_ATCC_1997      SVMPGDLAVWDG---HVAMVIGNGMMVEA---GDPVQISPIRTTNAGQGF
                                     : ***: .: .   *..: :* . *:.:   * **:: *: ::..  . 

Mb2213c|M.bovis_AF2122/97           RRY-----
Rv2190c|M.tuberculosis_H37Rv        RRY-----
MMAR_3234|M.marinum_M               RRY-----
MUL_3545|M.ulcerans_Agy99           RRY-----
MAV_2304|M.avium_104                RRY-----
MLBr_00885|M.leprae_Br4923          RRY-----
Mflv_4838|M.gilvum_PYR-GCK          QGFWRPTV
Mvan_1599|M.vanbaalenii_PYR-1       QGFWRPTA
MSMEG_1686|M.smegmatis_MC2_155      QGFWRPTA
TH_1643|M.thermoresistible__bu      QGFWRPTG
MAB_3664|M.abscessus_ATCC_1997      HGFYRPTS
                                    : :