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MVETSPISPSRLSEAVNTNYPDFSNNPFSSGLIGPAMDMAGTVGPGQFKEGQDPSKMLESGMQVMQQVMQ QGLQAGSSLIGSFAGAAAQALGQFAGMAGQALSSMATRSGAMGANVGQASESTARATSLITEALQEFQHT SEALTPLLWVPGVAAELAEAASRCTARVAEHTAQLEGELAGQAGELTGMAGADMGNPATPASGSVQPAMS AMQGGLQAGTQAMSGVASGVTQTMSSMGQGLGQIPQALTGLLSGAGGGSGSASALAGGSGLNGIAAGALA NPFGAGGGHASSTAGGTSSGLGSANASAAKMLLDPRSMGKGVQLFLPDGSTSQAPNAAAAEAVRKALSQV GVPYEWGGTKPGVGLDCSGLTQWAYGQSGVDIPRLAQEQGVGVKVDQGSVMPGDLAVWDGHVAMVIGNGM MVEAGDPVQISPIRTTNAGQGFHGFYRPTS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3664 | - | - | 100% (450) | hypothetical protein MAB_3664 |
| M. abscessus ATCC 19977 | MAB_1974 | - | 2e-17 | 40.17% (117) | hypothetical protein MAB_1974 |
| M. abscessus ATCC 19977 | MAB_2727c | - | 4e-13 | 30.05% (203) | invasion protein Inv2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2213c | - | 1e-14 | 36.67% (120) | hypothetical protein Mb2213c |
| M. gilvum PYR-GCK | Mflv_4838 | - | 1e-68 | 39.14% (419) | NLP/P60 protein |
| M. tuberculosis H37Rv | Rv0024 | - | 7e-17 | 44.76% (105) | putative secreted protein P60-related protein |
| M. leprae Br4923 | MLBr_00885 | - | 8e-16 | 36.89% (122) | putative secreted protein |
| M. marinum M | MMAR_0043 | - | 6e-17 | 48.00% (100) | secreted protein P60-related protein |
| M. avium 104 | MAV_0042 | - | 3e-16 | 47.96% (98) | NLP/P60 family protein |
| M. smegmatis MC2 155 | MSMEG_1686 | - | 1e-67 | 38.42% (419) | NPL/P60-family protein secreted protein |
| M. thermoresistible (build 8) | TH_1643 | - | 9e-70 | 44.73% (351) | NPL/P60-family protein secreted protein |
| M. ulcerans Agy99 | MUL_3545 | - | 1e-16 | 27.24% (301) | hypothetical protein MUL_3545 |
| M. vanbaalenii PYR-1 | Mvan_1599 | - | 3e-71 | 39.34% (427) | NLP/P60 protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4838|M.gilvum_PYR-GCK -----------------------MPSATVEALAAPIRRVQGLVGPGWSGD
Mvan_1599|M.vanbaalenii_PYR-1 -----------------------MPSAIVTALAAPIRRVQALVGPGWSAD
MSMEG_1686|M.smegmatis_MC2_155 -----------------------MPGALVHALAAPLHDLRTLVGPGWVAT
TH_1643|M.thermoresistible__bu --------------------------------------VRRWVWP-----
MAB_3664|M.abscessus_ATCC_1997 MVETSPISPSRLSEAVNTNYPDFSNNPFSSGLIGPAMDMAGTVGPGQFKE
Rv0024|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0042|M.avium_104 --------------------------------------------------
MMAR_0043|M.marinum_M --------------------------------------------------
Mb2213c|M.bovis_AF2122/97 -------------------MRLDQRWLIARVIMRSAIGFFASFTVSSGVL
MUL_3545|M.ulcerans_Agy99 -------------------MRLDCRQLTARVIRRSAIGSLASFTALSGFV
MLBr_00885|M.leprae_Br4923 -------------------MRLGCKHPVVRLIAHFVVGTLVGFAVLSRFF
Mflv_4838|M.gilvum_PYR-GCK PAADPSGALAGVRQMLSDVAGSAGHAWRTVDDRWSGAGADAAASFASATT
Mvan_1599|M.vanbaalenii_PYR-1 PAADPAAALTGVRDTLTEVADAAGRAWRDAEAGWSGSGGDAAARFAAATS
MSMEG_1686|M.smegmatis_MC2_155 --DPPVAALSSVRSALTDLAAAAEASWARVSDGWAGTASDAAGEFSAVTA
TH_1643|M.thermoresistible__bu -----------------------GIGSRPATDRRRRSSVXXXGRIAVA--
MAB_3664|M.abscessus_ATCC_1997 -GQDPSKMLESGMQVMQQVMQQGLQAGSSLIGSFAGAAAQALGQFAGMAG
Rv0024|M.tuberculosis_H37Rv ------------------MNYSEVELLSRAHQLFAGDSRRPGLDAGTTPY
MAV_0042|M.avium_104 ------------------MSHSELEALSRAHQLFAGGTRPASLDTGSGHY
MMAR_0043|M.marinum_M ------------------MIPTEVDALLRAHQMFVGTGDHRMPDVRPQPG
Mb2213c|M.bovis_AF2122/97 AANVLADPADDALAKLNELSRQAEQTTEALHSAQLDLNEKLAAQRAADQK
MUL_3545|M.ulcerans_Agy99 AAGAMADQAEDALAKLNELSRQAEQTTEAMHSAELELGAKLAAQQAAENK
MLBr_00885|M.leprae_Br4923 VATAMADPAEDALAKLNELSRQAEQTTEAVHSAQLDLTEKLAAQRAADKK
Mflv_4838|M.gilvum_PYR-GCK AAIDDAADRAGRLGVAAEDAAAAVGHAHRRLQQIVDEFESKARALEQRLD
Mvan_1599|M.vanbaalenii_PYR-1 AAIDGAAARAGQLGVTAGDAAAAVAGAHRRLQSIVDEFEARAGALEPHLD
MSMEG_1686|M.smegmatis_MC2_155 ATARALADRAGMLSGVAREAGTAVARAQARLDAVIEAFEQRAAALEPRLD
TH_1643|M.thermoresistible__bu -----LADAAARLAATTDTAAVAISDAAARLRVIIERFEARAGALEAHLD
MAB_3664|M.abscessus_ATCC_1997 QALSSMATRSGAMGANVGQASESTARATSLITEALQEFQHTSEALTPLLW
Rv0024|M.tuberculosis_H37Rv ---GDLLSRAADLNVGAGQRRYQLAVDHSRA------------ALLSAAR
MAV_0042|M.avium_104 ---RDLLGRAARLSDGFAHGGYRLAVQHSRQ------------RLASTSD
MMAR_0043|M.marinum_M ---AEPLRRATLPNPATDQPRYGFRAARGRE------------VLAAATR
Mb2213c|M.bovis_AF2122/97 LADNRTALDAARARLATFQTAVNKVAAATYMGGRTHGMDAILTAESPQLL
MUL_3545|M.ulcerans_Agy99 LTDDQAALDATKGQLASFQTAVNKVAAAAYMGGRANGMDTILTAPSPQLL
MLBr_00885|M.leprae_Br4923 YTDDQAALADAQVRLATFQAAVNKLAAATYMSGRINGMTALLTAYSPQQL
Mflv_4838|M.gilvum_PYR-GCK DPGVARELLTAARDALGEAIAVVEELQTELDRQARIVDSAAPAGS-----
Mvan_1599|M.vanbaalenii_PYR-1 SPGVARELLAEARDALRRAVAVVEELLAELDGHTAAAGAVAPAGS-----
MSMEG_1686|M.smegmatis_MC2_155 EPGVAEELVAEAQRALREALAVIEELRAELDGHAGTVTSAPVA-------
TH_1643|M.thermoresistible__bu EPGVAAELIAEARQALAEALGVVDDLHTDLARHATALTDPAGTPP-----
MAB_3664|M.abscessus_ATCC_1997 VPGVAAELAEAASRCTARVAEHTAQLEGELAGQAGELTGMAGADMGNPAT
Rv0024|M.tuberculosis_H37Rv TDAAAGAVITGAQRDRAWARRSTGTVLDEARSDTTVTAVMPIAQR-----
MAV_0042|M.avium_104 TDAAVTDLLAGAHRDRAQARELTGAVLDAGRADAAANPTTPLAQR-----
MMAR_0043|M.marinum_M TDAAVAAVIADAHRDREQARELTGNVVNQARADGVAPPVTPLAQR-----
Mb2213c|M.bovis_AF2122/97 IDRLSVQRVMAHQMSTQMARFKAAGEQAVKAEQAAAKSAADARSAAEQ--
MUL_3545|M.ulcerans_Agy99 IDGLSMQRVMVHQMATQMSGFRTAREQTAKAEQASEKSAADAKSAAEQ--
MLBr_00885|M.leprae_Br4923 INKLALQRVLGVQMATQMAGYRDAGEQAVKAEQTSAKSAADAKHAADQ--
.
Mflv_4838|M.gilvum_PYR-GCK PP---------TTPAEWQSASGTGG-------------------------
Mvan_1599|M.vanbaalenii_PYR-1 PAVAPAGSPAVTAPAGWSGAGGAGP-------------------------
MSMEG_1686|M.smegmatis_MC2_155 ------------VPAGFSGAVPAMR-------------------------
TH_1643|M.thermoresistible__bu SAR--------TVPSGFTGGSPPLGGMGSGLGGLPS--------------
MAB_3664|M.abscessus_ATCC_1997 PASGSVQPAMSAMQGGLQAGTQAMSGVASGVTQTMSSMGQGLGQIPQALT
Rv0024|M.tuberculosis_H37Rv --------------EAIRRRVARLR-------------------------
MAV_0042|M.avium_104 --------------EAMRRRVMRLR-------------------------
MMAR_0043|M.marinum_M --------------EAIRRRVGRLR-------------------------
Mb2213c|M.bovis_AF2122/97 ---------AAAVRANLQHKQSQLQVQ-----------------------
MUL_3545|M.ulcerans_Agy99 ---------AAAVRANLQHKQSQLQVQ-----------------------
MLBr_00885|M.leprae_Br4923 ---------AAVVRAGLQSKQSKLQLQ-----------------------
Mflv_4838|M.gilvum_PYR-GCK ----GPGGGFAPGSGGFGNSGATGEMA-AFTRPDGT--------------
Mvan_1599|M.vanbaalenii_PYR-1 ----GPGGAPAGWAGPGAVNGGFGELA-GFTPVEAT--------------
MSMEG_1686|M.smegmatis_MC2_155 ----ASG---FSGLGPNLGSGSPSAFAPAFSAPEAAPG------------
TH_1643|M.thermoresistible__bu ---VSPGGAAGSGLGGGAARGLAELVGLATDRPDSAA-------------
MAB_3664|M.abscessus_ATCC_1997 GLLSGAGGGSGSASALAGGSGLNGIAAGALANPFGAGGGHASSTAGGTSS
Rv0024|M.tuberculosis_H37Rv -----AQRAHVLTARRRARRHLAALRALRYRVAHGPG-------------
MAV_0042|M.avium_104 -----TQHAHVVSAAARARHHHARLLALRYRLRHG---------------
MMAR_0043|M.marinum_M -----AQRAHVLWAHRRARRRLAALRLLRYRMLHH---------------
Mb2213c|M.bovis_AF2122/97 ---IAVVKSQYVALTPEERTALADPGPVPAVAAIAPGAPPAALPPG----
MUL_3545|M.ulcerans_Agy99 ---IAVVKSQYLALTPDQRTALVDPGQVPAGLPGAPGPAPEGTPPGG---
MLBr_00885|M.leprae_Br4923 ---IAVVKSHYLSLSPRQRTTLAEPGPVPAVAT-LPGAASAGVSPP----
Mflv_4838|M.gilvum_PYR-GCK -----------DTPDAAEFGEGVAVRLPDGTVVVAPNAVAANAVRHALTQ
Mvan_1599|M.vanbaalenii_PYR-1 -----------GTPDAATFGDGVAVRLPDGTVVMAPNAVAASAVRHALTQ
MSMEG_1686|M.smegmatis_MC2_155 --------GLLDTPDAAMFGDGVAVRLPDGSTTMAPNAVAASAVRHALTQ
TH_1643|M.thermoresistible__bu -----------RPADPAAFGVGVAVRLPDGSTVTAPNAVAADAVRHALTQ
MAB_3664|M.abscessus_ATCC_1997 GLGSANASAAKMLLDPRSMGKGVQLFLPDGSTSQAPNAAAAEAVRKALSQ
Rv0024|M.tuberculosis_H37Rv -------------------------VALAKLRLPSPSGRAGIAVHAALSR
MAV_0042|M.avium_104 -------------------------VGLAGLRGPG-SDRAALAVRAALSR
MMAR_0043|M.marinum_M --------------------------HGSRQRLSPISGRAGIAVRAALSR
Mb2213c|M.bovis_AF2122/97 -----APPGDGPAPGVAPPP--GGMPGLPFVQPDGAGGDRTAVVQAALTQ
MUL_3545|M.ulcerans_Agy99 -----PPPAGAPVPGEAPPPGAGGVSAMPFTPPDGAGGDRAAVVQAALTQ
MLBr_00885|M.leprae_Br4923 -------------PDAAPPGGLLGVAPAPFAG----GGDRAAVVQAALTQ
. .*: **::
Mflv_4838|M.gilvum_PYR-GCK LGVPYQWGGTTPGVGLDCSGLTQWAYREAGLDIPRLAQEQD-IGGAVSGG
Mvan_1599|M.vanbaalenii_PYR-1 LGVPYQWGGTTPGVGLDCSGLTQWAYREAGLSLPRLAQEQD-LGAAVGAG
MSMEG_1686|M.smegmatis_MC2_155 LGVPYHWGGTTPGVGLDCSGLTQWAYREAGLNIPRLAQEQD-IGAAVAAN
TH_1643|M.thermoresistible__bu LGVPYQWGGTTPGVGLDCSGLTQWAYQQAGLQLPRLAQEQD-VGAAVDAG
MAB_3664|M.abscessus_ATCC_1997 VGVPYEWGGTKPGVGLDCSGLTQWAYGQSGVDIPRLAQEQG-VGVKVDQG
Rv0024|M.tuberculosis_H37Rv LGRPYVWGATGPNQ-FDCSGLVQWAYAQAGVHLDRTTYQQINEGIPVPRS
MAV_0042|M.avium_104 LGRPYVWGATGPDQ-FDCSGLVQWSYAQAGIHLDRTTYQQINEGIPVPRS
MMAR_0043|M.marinum_M LGRPYVWGATGPDR-FDCSGLVQWAYAQAGVHLDRTTYQQINDGIVVSRS
Mb2213c|M.bovis_AF2122/97 VGAPYAWGGAAPGG-FDCSGLVMWAFQQAGIALPHSSQALAHGGQPVALS
MUL_3545|M.ulcerans_Agy99 VGTPYAWGGAAPGG-FDCSGLVMWAFQQAGIALPHSSQALAHEGQPVSLS
MLBr_00885|M.leprae_Br4923 IGSPYAWGGAAPGG-FDCSGLVMWAYQQAGIALPHSSQALARGGQPVSLS
:* ** **.: *. :*****. *:: ::*: : : : * * .
Mflv_4838|M.gilvum_PYR-GCK SLLPGDLAV---WDGHVAMVVGDGLMVEAGDPVQLSPIRTANAGQGFQGF
Mvan_1599|M.vanbaalenii_PYR-1 SLLPGDLAV---WDGHVAMIVGDGTMIEAGDPVKLSPIRTANAGQGFQGF
MSMEG_1686|M.smegmatis_MC2_155 ALRPGDLAV---WDGHVAMIVGPNTMIEAGDPVQLSPIRTTNAGQGFQGF
TH_1643|M.thermoresistible__bu ALLPGDLAV---WDGHVAMVVGNGMMIEAGDPVKLSPIRTTNAGQGFQGF
MAB_3664|M.abscessus_ATCC_1997 SVMPGDLAV---WDGHVAMVIGNGMMVEAGDPVQISPIRTTNAGQGFHGF
Rv0024|M.tuberculosis_H37Rv QVRPGDLVFP--HPGHVQLAIGNNLVVEA--PHAGASVRVSSLGNNVQ-I
MAV_0042|M.avium_104 QVRPGDLVFP--HAGHVQLAIGNNLVVEA--PYSGASVRISRLGNNVA-I
MMAR_0043|M.marinum_M HIRPGDLVFP--HPGHVQLAIGNNLVVEA--PHAGASVRISPLGNHVQ-I
Mb2213c|M.bovis_AF2122/97 DLQPGDVLTFYSDASHAGIYIGDGLMVHS--STYGVPVRVVPMDSSGPIY
MUL_3545|M.ulcerans_Agy99 DLQPGDVLTFYSDASHAGIYIGDGLMVHS--STYGVPVRVVPMNSSGPIY
MLBr_00885|M.leprae_Br4923 ELQPGDVLTFYSDASHAGIYVGDGMMIHS--STYGVPVRVVPMNSSGPIY
: ***: .*. : :* . ::.: . .:* ..
Mflv_4838|M.gilvum_PYR-GCK WRPTV--
Mvan_1599|M.vanbaalenii_PYR-1 WRPTA--
MSMEG_1686|M.smegmatis_MC2_155 WRPTA--
TH_1643|M.thermoresistible__bu WRPTG--
MAB_3664|M.abscessus_ATCC_1997 YRPTS--
Rv0024|M.tuberculosis_H37Rv RRPLSGR
MAV_0042|M.avium_104 RRPI---
MMAR_0043|M.marinum_M RRPL---
Mb2213c|M.bovis_AF2122/97 DARRY--
MUL_3545|M.ulcerans_Agy99 DARRY--
MLBr_00885|M.leprae_Br4923 DARRY--