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M. thermoresistible (build 8) TH_1507 (-)

annotation: flavoprotein
coordinates: 2843445 - 2845055
length: 537

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1507--100% (537)flavoprotein
M. thermoresistible (build 8)TH_3358-2e-2927.19% (445) PUTATIVE FAD linked oxidase domain protein
M. thermoresistible (build 8)TH_0754-3e-2125.86% (437) D-2-hydroxyglutarate dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2275-0.074.10% (529) flavoprotein
M. gilvum PYR-GCKMflv_2772-0.078.14% (526) alkylglycerone-phosphate synthase
M. tuberculosis H37RvRv2251-0.077.12% (424) flavoprotein
M. leprae Br4923MLBr_02631-1e-2525.05% (483) putative oxidoreductase
M. abscessus ATCC 19977MAB_3884-1e-17959.89% (526) flavoprotein
M. marinum MMMAR_3344-0.073.95% (526) flavoprotein
M. avium 104MAV_2186-0.075.05% (537) flavoprotein
M. smegmatis MC2 155MSMEG_4334-0.078.52% (526) flavoprotein
M. ulcerans Agy99MUL_1298-0.073.38% (526) flavoprotein
M. vanbaalenii PYR-1Mvan_3761-0.077.19% (526) alkylglycerone-phosphate synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2275|M.bovis_AF2122/97            -----------MKWDAWGDPAAAKPLSDGVRSLLKQVVGLADSEQPELDP
Rv2251|M.tuberculosis_H37Rv         -----------MRWRASSAPSISAPP------------------------
MMAR_3344|M.marinum_M               -----------MKWNAWGDPAAAKPLSDGIRALLKQVVGLEDSGEAELGA
MUL_1298|M.ulcerans_Agy99           -----------MKWNAWGDPAAAKPLSDGIRALLKQVVGLEDSDEAELGA
MAV_2186|M.avium_104                -MTHPERLLPPMKWNAWGDPAAAKPLSEGIRSLLQQAVGIEGSRAAEPRP
Mflv_2772|M.gilvum_PYR-GCK          ----------MMQWNAWGDPDAAKPLSPGIRSLLHQALGIDGTPLDEPTL
Mvan_3761|M.vanbaalenii_PYR-1       ----------MMQWNAWGDPAAAKPLSPAIRALLGQALGIDGADIDEPTL
MSMEG_4334|M.smegmatis_MC2_155      -----------MKWNAWGDPQAAKPLSDGIRALLQQALGVTDSP-AQISP
TH_1507|M.thermoresistible__bu      MSAPENHLSPPMKWNAWGDPAAARPLSDGIRSLLREALGVEGPPTPDLSP
MAB_3884|M.abscessus_ATCC_1997      ----------MMEWDAWGVAEKRQTLSPQVKALLASALGIPEREPVHRDE
MLBr_02631|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2275|M.bovis_AF2122/97            AQVQLRPSALSGADHDALARIVGTEYFRTADRDRLLHAGGKSTPDLLRRK
Rv2251|M.tuberculosis_H37Rv         ---------------------IATGCCTPAASPPQTCCGAKTPVSRMR--
MMAR_3344|M.marinum_M               DQVKLRPCALSQSDQDALAKIVGPEYMRTADRDRLLRAGGKSTPDMLRRK
MUL_1298|M.ulcerans_Agy99           DQVKLRPCALSQSDQDALAKIVGPEYMRTADRDRLLRAGGKSTPDMLRRK
MAV_2186|M.avium_104                EQVRLRPSTLSPADREALAAIVGPEYCRTADSDRLLHAGGKSTIDLLSRN
Mflv_2772|M.gilvum_PYR-GCK          DQVRLRPSALSPGDRDGLSAIIGAEHVTVDDRARLLRAGGKSTLDLLRRR
Mvan_3761|M.vanbaalenii_PYR-1       EQVRLRPSALSPADLDGLSAVVGAANVTTDDQARLLRAGGKSTLDLLRRR
MSMEG_4334|M.smegmatis_MC2_155      EDITLRPSALTAADRDALAAVVGEQYCRTDDTARLLHAGGKSTLDLLRRN
TH_1507|M.thermoresistible__bu      DQVRLRPSALSDADRDALAGVVGADFCRVDEHSRLLHAGGKSTLDLLRRR
MAB_3884|M.abscessus_ATCC_1997      SHVTLTPNSLTDAQRAALGGLLGAEHVSTDHGARLRHSGGKSTPDLLRRR
MLBr_02631|M.leprae_Br4923          -------------MLRSLAAVVGSSHVIADPDVLIAHSIDHTG-------
                                                         :.              .  ::        

Mb2275|M.bovis_AF2122/97            DTGVQDAPDAVLLPGGPNGEDAVADILHYCSDHGIAVVPFGGGTSVVGGL
Rv2251|M.tuberculosis_H37Rv         -------PTRCCCPAAPTGEDAVADILHYCSDHGIAVVPFGGGTSVVGGL
MMAR_3344|M.marinum_M               DTGIQDAPDAVLLPG---DDQAVAEILRYCSDQGIAIVPFGGGTNVTGGL
MUL_1298|M.ulcerans_Agy99           DTGIQDAPDAVLLPG---DDQAVAEILRYCSDQGIAIVPFGGGTNVTGAL
MAV_2186|M.avium_104                GPGPQDAPDAVLLPG---DDESVAAILRYCSQHRIAVVPFGGGTSVVGGL
Mflv_2772|M.gilvum_PYR-GCK          DFGVQDAPDAVLLPG---GEDEIAEVLRYCAHRSIAVVPFGGGTSVVGGV
Mvan_3761|M.vanbaalenii_PYR-1       DFGVQDAPDAIVLPG---GDRDVAEVLRFCGERSIAVVPFGGGTSVVGGL
MSMEG_4334|M.smegmatis_MC2_155      TSGVQDAPDAILLPG---DEDAVAAILRYCTEHRIAIVPFGGGTSVVGGL
TH_1507|M.thermoresistible__bu      QPE-QDAPDAVVLPA---DEDQIAEILRICGSRRIAVVPFGGGTSVVGGL
MAB_3884|M.abscessus_ATCC_1997      STGVQNAPDAIVYPA---SHDEVSALLTLCEEQGIAVVPFGGGTSVVGGL
MLBr_02631|M.leprae_Br4923          --RYRGQARALVRPG---TAEQVTEVLRVCRDVGAHVTVQGGRTSLVAGT
                                           .     *.       :: :*  *      :.  ** *.:... 

Mb2275|M.bovis_AF2122/97            DPVRNDFRAVISLDMRRFDRLHRIDEVSGEAELEAGVTGPEAERLLGEHG
Rv2251|M.tuberculosis_H37Rv         DPVRNDFRAVISLDMRRFDRLHRIDEVSGEAELEAGVTGPEAERLLGEHG
MMAR_3344|M.marinum_M               DPNRGQFSAVISLDLRRFNELHSLDEVSGIAELGAGVTGPDAERLLGERG
MUL_1298|M.ulcerans_Agy99           DPNRGQFSAVISLDLRRFNELHSLDEVSGIADLGAGVTGPDAERLLGERG
MAV_2186|M.avium_104                TPERAGFGAAVAVDLRRFDQLISLDPVSGLAVLGAGVTGPDAEKLLGAHG
Mflv_2772|M.gilvum_PYR-GCK          DPLRGDFKAVVSLDLRRLDELHSLDDVSWEAELGAGLTGPEAERLLGERG
Mvan_3761|M.vanbaalenii_PYR-1       DPTRGDFKAVVSLDLRRLDELHSLDEVSWEAELGAGLTGPDAERLLGERG
MSMEG_4334|M.smegmatis_MC2_155      DPLRGEFGAVVSLDLRRLDALHHLDEISGEAELGAGVTGPQAEELLGAHG
TH_1507|M.thermoresistible__bu      DPIRGEFGSVVALDLRRLNRLIWLDEVSQLAELSAGMTGPAAEETLRARG
MAB_3884|M.abscessus_ATCC_1997      DPERGAFGAVIAIDLRRMSGLLSLDEVSGTAVLLPGTTGPEAEELLGAQG
MLBr_02631|M.leprae_Br4923          VPEHN----DVLLSTERLRSISEVDTVERRLRVGAGATLTAVQNAATAAG
                                     * :      : :. .*:  :  :* :.    : .* * . .:.     *

Mb2275|M.bovis_AF2122/97            FSLGHFPQSFEFATIGGFAATRSSGQDSAGYGRFNDMILGLRMITPVGVL
Rv2251|M.tuberculosis_H37Rv         FSLGHFPQSFEFATIGGFAATRSSGQDSAGYGRFNDMILGLRMITPVGVL
MMAR_3344|M.marinum_M               FSLGHFPQSFEYATIGGFAATRSSGQDSAGYGRFNDMIIGLRMITPAGVL
MUL_1298|M.ulcerans_Agy99           FSLGHFPQSFEYATIGGFAATRSSGQDSAGYGRFNDMIIGLRMITPAGVL
MAV_2186|M.avium_104                FSLGHFPQSFEYATIGGFAATRSSGQDSAGYGRFNDMVRGLRVITPVGTM
Mflv_2772|M.gilvum_PYR-GCK          FSLGHYPQSFLFATIGGFAATRSSGQDSAGYGRFNDMVRGLRAVTPAGVL
Mvan_3761|M.vanbaalenii_PYR-1       FSLGHFPQSFCFATIGGFAATRSSGQDSAGYGRFDDMVRGLRAVTPAGVL
MSMEG_4334|M.smegmatis_MC2_155      FSLGHFPQSFQFATIGGFAATRSSGQNSAGYGRFDDMVRGLRAVTPAGVL
TH_1507|M.thermoresistible__bu      FSLGHFPQSFEFASIGGFAATRSSGQNSAGYGRFNDMVRGVRAITPTGVL
MAB_3884|M.abscessus_ATCC_1997      FSLGHFPQSFRFASIGGFAATRSSGQASSGYGRFDAMVDAVRIATPRGDL
MLBr_02631|M.leprae_Br4923          LVFGVDLCARATATVGGMASTNAGGLRTVRYGNMGEQVIGLEVALPDGSL
                                    : :*    :   *::**:*:*.:.*  :  **.:.  : .:.   * * :

Mb2275|M.bovis_AF2122/97            DLGRVPA--SAAGPDLRQLAIGSEGVFGVITRVRLRVHRIPESTRYEAWS
Rv2251|M.tuberculosis_H37Rv         DLGRVPA--SAAGPDLRQLAIGSEGVFGVITRVRLRVHRIPESTRYEAWS
MMAR_3344|M.marinum_M               DLGRVAA--SAAGPDLRQLAIGSEGVFGVITKVRLRVHPVPETTRYEAWS
MUL_1298|M.ulcerans_Agy99           DLGRVAA--SAAGPDLRQLAIGSEGVFGVITKVRLRVHPVPETTRYEAWS
MAV_2186|M.avium_104                DLGRGPE--SAAGPDLRQLLIGSEGTLGVITRVRLRVHRIPQAVRYEAWS
Mflv_2772|M.gilvum_PYR-GCK          DLGRAPE--SAAGPDLRQLLIGSEGAFGIITRVRVRVHPVPEVTRYEAWS
Mvan_3761|M.vanbaalenii_PYR-1       DLGRAPA--SAAGPDLRQLLLGSEGTFGIITRVRVRVHPVPEATRYEAWS
MSMEG_4334|M.smegmatis_MC2_155      DLGRAPA--SAAGPDLRQLLLGSEGVFGVITRVRVRVHPVPESTRYEAWS
TH_1507|M.thermoresistible__bu      DLGRAPE--SAAGPDLRHLLIGSEGVFGVITRVRVRVRPVPEAVRYEAWS
MAB_3884|M.abscessus_ATCC_1997      NLGRAPA--SAAGPDLRQLFLGSEGALGIITEVTLRVHRLPEETWYQGWS
MLBr_02631|M.leprae_Br4923          LCRHSLARFDNTGYNLPALFVGAEGTLGVITALDLRLHPAPAHRVTAVCG
                                       :     . :* :*  * :*:**.:*:** : :*::  *        .

Mb2275|M.bovis_AF2122/97            FPDFATGVAALRTITQTGTGPTVVRLSDEAETGVNLATTEAIGETQITGG
Rv2251|M.tuberculosis_H37Rv         FPDFATGVAALRTITQTGTGPTVVRLSDEAETGVNLATTEAIGETQITGG
MMAR_3344|M.marinum_M               FPDFSTGVAALRAITQTGTGPTVVRLSDEAETGINLATHESIGENQVTGG
MUL_1298|M.ulcerans_Agy99           FPDFSTGVAALRAITQTGTGPTVVRLSDEAETGINLATHESIGENQVTGG
MAV_2186|M.avium_104                FPDFETGAAALRAVTQNGTGPTVIRLSDEAETGVNLATTEAIGESRITGG
Mflv_2772|M.gilvum_PYR-GCK          FPDFATGADALRAVVQTGTGPTVIRLSDEAETGVNLATTENIGEQKITGG
Mvan_3761|M.vanbaalenii_PYR-1       FPDFATGADALRAVAQTGTGPTVIRLSDEAETGVNLATTESIGEQQVTGG
MSMEG_4334|M.smegmatis_MC2_155      FPDFATGADALRAVVQTGTGPTVIRLSDEAETGVNLATTDNIGEQSITGG
TH_1507|M.thermoresistible__bu      FPDFATGTAALRAVTQIGTGPTVIRLSDEAETGVNLATTDNIGDQSITGG
MAB_3884|M.abscessus_ATCC_1997      FPSFEAGAQALRTLVQSDAAPTVLRLSDEAESGLNLALAKDIGGKNPAAG
MLBr_02631|M.leprae_Br4923          FSDLGALVDASRAFRDVYGIAALELIDGRASS----LIREHLGVSSPVDG
                                    *..: : . * *:. :    .::  :...*.:       . :*    . *

Mb2275|M.bovis_AF2122/97            CLGITVFEGTQEHTESRHAETRALLAARGGTSLGEGPARAWERGRFAAPY
Rv2251|M.tuberculosis_H37Rv         CLGITVFEGTQEHTESRHAETRALLAARGGTSLGEGPARAWERGRFAAPY
MMAR_3344|M.marinum_M               CLGLTLFEGTKEHTESRHAETRASLEAHGGKSLGEGPAQSWEHGRFSAPY
MUL_1298|M.ulcerans_Agy99           CLGLTLFEGTKEHTESRHAETRASLEAHGGKSLGEGPAQGWEHGRFSAPY
MAV_2186|M.avium_104                CLCITMFEGTEQHVDSRHAETRALLAAQGGTSLGDGPARAWERGRFGAPY
Mflv_2772|M.gilvum_PYR-GCK          CLAITAFEGTEAHVASRHAETRDLLAAKGGTSLGEAPAKAWEHGRFNAPY
Mvan_3761|M.vanbaalenii_PYR-1       CLAITAFEGTEAHVASRHAETRDLLAASGGTSLGEGPARAWEHGRFNAPY
MSMEG_4334|M.smegmatis_MC2_155      CLAVTVFEGSPEHTASRHAETRALLERLGGTSLGEVPARAWEHGRFGAPY
TH_1507|M.thermoresistible__bu      CLAITVFEGTAAHAESRHAETAAVLAAHGGTSLGEEPARAWEHGRFSAPY
MAB_3884|M.abscessus_ATCC_1997      VLAITTVEGTHGHVAARSAEVAAVLSAAGGTALGDEPAKAWDHGRFDAPY
MLBr_02631|M.leprae_Br4923          DWLLLVELAADHDQTNRLAELSMAVQMCGVPAVG--VDAGAQQRLWRVRE
                                       :    .:  .   * **    :   *  ::*     . ::  : .  

Mb2275|M.bovis_AF2122/97            LRDSLLAAGALCETLETATVWSNTPVLKAAVTEALTTSLAASGTPALVMC
Rv2251|M.tuberculosis_H37Rv         LRDSLLAAGALCETLETATVWSNTPVLKAAVTEALTTSLAASGTPALVMC
MMAR_3344|M.marinum_M               LRDSLLAAGALCETLETATDWSNIAAVKAAVTEALTTSLAESGTPALVMC
MUL_1298|M.ulcerans_Agy99           LRDSLLAASALCETLETATDWSNIAAVKAAVTEALTTSLAESGTPALVMC
MAV_2186|M.avium_104                LRDSLLAAGALCETLETATDWSNISALKAAVTQALTTALAQTGTPALVMC
Mflv_2772|M.gilvum_PYR-GCK          LRDALLSAGALCETLETATNWSNVAALKAAVTEALTRSLEDSGTPALVLC
Mvan_3761|M.vanbaalenii_PYR-1       LRDALLSAGALCETLETATNWSNVAALKAAVTEALTGSLAESGTPALVLC
MSMEG_4334|M.smegmatis_MC2_155      LRDSLLAAGALCETLETATNWSNVAALKTAVTEALTATLAESGTQALVLC
TH_1507|M.thermoresistible__bu      LRDSLLSAGALCETLETATTWSNIPTLKAAVTDALTSTLGESGTSALVMC
MAB_3884|M.abscessus_ATCC_1997      LRDALIDAGAVVETLETATSWQNLANLRTAVTTALAETLGAQGTPPLVLC
MLBr_02631|M.leprae_Br4923          SLAEVLGVYGPPLKFDVSLPLSAISGFAKEAATLIDAQVSDVQEALPVLF
                                        :: . .   .::.:   .  . .   .:  :   :        *: 

Mb2275|M.bovis_AF2122/97            HVSHVYPTGASLYFTVVAGQRGDPIEQWLAAKKAASDAIMATGGTITHHH
Rv2251|M.tuberculosis_H37Rv         HVSHVYPTGASLYFTVVAGQRGDPIEQWLAAKKAASDAIMATGGTITHHH
MMAR_3344|M.marinum_M               HVSHVYPTGASLYFTVVAGQRGNPIEQWMAAKKAASDAMMATGATITHHH
MUL_1298|M.ulcerans_Agy99           HVSHVYPTGASLYFTVVAGQRGNPIEQWMAAKKAASDAMMATGATITHHH
MAV_2186|M.avium_104                HISHVYPTGASLYFTVVAGQRGDPIEQWKTAKKAASDAIMATGGTITHHH
Mflv_2772|M.gilvum_PYR-GCK          HISHVYPTGASLYFTVVAAQRGNPIEQWRKAKAAASDAMVRTGATITHHH
Mvan_3761|M.vanbaalenii_PYR-1       HISHVYPTGASLYFTVVAAQRGNPIEQWRNAKAAASEAMLRSGATITHHH
MSMEG_4334|M.smegmatis_MC2_155      HISHVYPTGASLYFTVVAAQRGDAAEQWRKAKTAASEAMVRNGATITHHH
TH_1507|M.thermoresistible__bu      HISHVYPTGASLYFTVVAAQRGNPIEQWRTAKAAASDAMMRHGGTITHHH
MAB_3884|M.abscessus_ATCC_1997      HISHTYRTGASLYFTVVCAAAEDALTQWGRAKQAAGDAIVAAGGTITHHH
MLBr_02631|M.leprae_Br4923          G----HVGEGNLHLNVLR----CPPDREKTLTAAMMELIAQAGGNVSSEH
                                         :   ..*::.*:      .  :    . *  : :   *..:: .*

Mb2275|M.bovis_AF2122/97            AVGSDHRPWMRAEVGDLGVTLLRTIKATLDPAGILNPGKLIP---
Rv2251|M.tuberculosis_H37Rv         AVGSDHRPWMRAEVGDLGVTLLRTIKATLDPAGILNPGKLIP---
MMAR_3344|M.marinum_M               AVGADHRPWMRDEVGDLGVQLLRAVKATLDPAGILNPGKLIP---
MUL_1298|M.ulcerans_Agy99           AVGADHRPWMRDEVGDLGVQLLRAVKATLDPAGILNPGKLIP---
MAV_2186|M.avium_104                AVGTDHRPWMPEEIGELGVQVLRAVKDTLDPAGILNPGKLIP---
Mflv_2772|M.gilvum_PYR-GCK          AVGADHRPWMTDEVGGLGVSVLRAVKSVLDPAGILNPGKLIP---
Mvan_3761|M.vanbaalenii_PYR-1       AVGADHRPWMRDEIGDLGVTVLRAVKEALDPAGILNPGKLIP---
MSMEG_4334|M.smegmatis_MC2_155      AVGADHRPWMTEEVGDLGVAVLRAVKATLDPAGILNPGKLIP---
TH_1507|M.thermoresistible__bu      AVGADHRPWMRDEVGGLGVDILRAVKATLDPAGILNPGKLIP---
MAB_3884|M.abscessus_ATCC_1997      AVGRDHQPWLADEVGELGIEILQAVKRTVDPRGILNPGKLIPVQG
MLBr_02631|M.leprae_Br4923          GVGSNKRAYLRMSRDPADIAAMRTIKAALDPTGYLNAAVLFD---
                                    .** :::.::  . .  .:  ::::* .:** * **.. *: