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MPDSDARLASDLSLAVMRLARQLRFRNPSSPVSLSQLSALAMLANEGPMTPGALAVRERVRPPSMTRVIA SLAEMGLVDRTPHPVDGRQVLVSVSEAGAELVKANRRARQEWLAKRLVHAGRRRARNPAPRGRSDAGPGR RRPVNTDALDVRDVDDPDDPRLDDFRDLNSVDRRPDLPSGKGLVIAEGVLVVQRMLASRFRPHALLGTER RLAELRDDLAGVPVPYYRTSADVMARVVGFHLNRGVLAAARRVPEPGVAELLAGSRTVAVLEGVNDHENL GAIFRNAAGLGVDAVIFGSGCADPLYRRAVRVSMGHALLVPYARATDWPAELKTLKEKGFRLLAMTPQGS ACGLAEAMTAARGDRVAVLVGAEGPGLTPAALRLSDVRVRIPMSRGTDSLNVATAAALAFYERSRPVGGH RAAAGGGDGQSG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1009 | - | - | 100% (432) | SpoU rRNA methylase family protein |
| M. avium 104 | MAV_3123 | - | 1e-17 | 32.94% (170) | TsnR protein |
| M. avium 104 | MAV_4734 | - | 8e-17 | 39.13% (115) | MarR-family protein regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0905 | - | 1e-129 | 82.08% (279) | rRNA methyltransferase |
| M. gilvum PYR-GCK | Mflv_1715 | - | 1e-110 | 74.72% (265) | tRNA/rRNA methyltransferase (SpoU) |
| M. tuberculosis H37Rv | Rv0881 | - | 1e-128 | 81.72% (279) | rRNA methyltransferase |
| M. leprae Br4923 | MLBr_02140 | - | 3e-52 | 87.29% (118) | putative MarR-family protein |
| M. abscessus ATCC 19977 | MAB_0881 | - | 1e-111 | 76.60% (265) | putative tRNA/rRNA methyltransferase |
| M. marinum M | MMAR_4651 | - | 1e-124 | 83.52% (267) | rRNA methyltransferase |
| M. smegmatis MC2 155 | MSMEG_5687 | - | 1e-111 | 74.91% (271) | 23s ribosomal RNA methyltransferase |
| M. thermoresistible (build 8) | TH_1372 | - | 1e-114 | 75.72% (276) | POSSIBLE RRNA METHYLTRANSFERASE (RRNA METHYLASE) |
| M. ulcerans Agy99 | MUL_0269 | - | 1e-121 | 82.26% (265) | rRNA methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_5036 | - | 1e-112 | 76.40% (267) | tRNA/rRNA methyltransferase (SpoU) |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1715|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5036|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1372|M.thermoresistible__bu --------------------------------------------------
MSMEG_5687|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0881|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0905|M.bovis_AF2122/97 --------------------------------------------------
Rv0881|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4651|M.marinum_M --------------------------------------------------
MUL_0269|M.ulcerans_Agy99 --------------------------------------------------
MAV_1009|M.avium_104 MPDSDARLASDLSLAVMRLARQLRFRNPSSPVSLSQLSALAMLANEGPMT
MLBr_02140|M.leprae_Br4923 --------------------------------------------------
Mflv_1715|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5036|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1372|M.thermoresistible__bu --------------------------------------------------
MSMEG_5687|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0881|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0905|M.bovis_AF2122/97 --------------------------------------------------
Rv0881|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4651|M.marinum_M --------------------------------------------------
MUL_0269|M.ulcerans_Agy99 --------------------------------------------------
MAV_1009|M.avium_104 PGALAVRERVRPPSMTRVIASLAEMGLVDRTPHPVDGRQVLVSVSEAGAE
MLBr_02140|M.leprae_Br4923 --------------------------------------------------
Mflv_1715|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5036|M.vanbaalenii_PYR-1 -------------------------------------------MIANNVE
TH_1372|M.thermoresistible__bu ----------------------------VHTLSGPNPDDPDGPDVTDGPD
MSMEG_5687|M.smegmatis_MC2_155 ---------------------------------------------MSPLQ
MAB_0881|M.abscessus_ATCC_1997 ------------------------------------------------ML
Mb0905|M.bovis_AF2122/97 ------------------------------------MTEGRCAQHPDGLD
Rv0881|M.tuberculosis_H37Rv ------------------------------------MTEGRCAQHPDGLD
MMAR_4651|M.marinum_M ------------------------------------MTA---HSHVRDVD
MUL_0269|M.ulcerans_Agy99 --------------------------------------------------
MAV_1009|M.avium_104 LVKANRRARQEWLAKRLVHAGRRRARNPAPRGRSDAGPGRRRPVNTDALD
MLBr_02140|M.leprae_Br4923 --------------------------------------------------
Mflv_1715|M.gilvum_PYR-GCK MVDITDPADPRLDPFRDLNSVDRRPDLPSGKGLVIAEGVLVVQRMLASRF
Mvan_5036|M.vanbaalenii_PYR-1 VVDVTDPADPRLDDFRDLNSVDRRPDLPSGKGLVIAEGVLVVQRMLASRF
TH_1372|M.thermoresistible__bu VTDITDPADPRVDDFRDLNSVDRRPDLPGGKGLVIAEGVLVVQRMLASRF
MSMEG_5687|M.smegmatis_MC2_155 VIDIDDPADPRIDDFRDLNSVDRRPDLPTGKALVIAEGVLVVQRMLASRF
MAB_0881|M.abscessus_ATCC_1997 VIDVHDPADSRLDSFRDLNSVDRRPDLPSGKGLVIAEGVLVVQRMLASRF
Mb0905|M.bovis_AF2122/97 VQDVCDPDDPRLDDFRDLNSIDRRPDLPTGKALVIAEGVLVVQRMLASRF
Rv0881|M.tuberculosis_H37Rv VQDVCDPDDPRLDDFRDLNSIDRRPDLPTGKALVIAEGVLVVQRMLASRF
MMAR_4651|M.marinum_M VRDVSDPDDPCLDDFRDLNSIDRRPDLPSGKGLVIAEGVLVVQRMLASRF
MUL_0269|M.ulcerans_Agy99 MRDVSDPDDPCLDDFRDLNSIDRRPDLPSGKGLVIAEGVLVVQRMLASRF
MAV_1009|M.avium_104 VRDVDDPDDPRLDDFRDLNSVDRRPDLPSGKGLVIAEGVLVVQRMLASRF
MLBr_02140|M.leprae_Br4923 -------------------MLDSDARLASDLSLAVMR--LARQLRFRNPQ
:* . *. . .*.: . *. * : .
Mflv_1715|M.gilvum_PYR-GCK VPRALLGTDRRLTELGTDLDG----LAAPFYRATAEVMAEAIGFHLNRGV
Mvan_5036|M.vanbaalenii_PYR-1 VPRALLGTDRRLTELGTDLAG----LDAPFYRASAEVMADVVGFHLNRGV
TH_1372|M.thermoresistible__bu TPRAFLGTDRRLTELRADLAA----VDAPFYRADAEVMAEVVGFHLNRGV
MSMEG_5687|M.smegmatis_MC2_155 IPRALLGTDRRLGELAADLDRYPQYADVPFYRASAEVMAEAIGFHLNRGV
MAB_0881|M.abscessus_ATCC_1997 RPLALLGTDRRLSELAADLEP----VDVPYYRASAEVMAEVVGFHLNRGV
Mb0905|M.bovis_AF2122/97 TPLALFGTDRRLAELKDDLAG----VGAPYYRASADVMARVIGFHLNRGV
Rv0881|M.tuberculosis_H37Rv TPLALFGTDRRLAELKDDLAG----VGAPYYRASADVMARVIGFHLNRGV
MMAR_4651|M.marinum_M SPRALLGTDRRLLELKDDLAG----VGVPYYRVSPDVMAQVVGFHLNRGV
MUL_0269|M.ulcerans_Agy99 SPRALLGTDRRLLELKEDLAG----VGAPYYRVSPDVMAQVVGFHLNRGV
MAV_1009|M.avium_104 RPHALLGTERRLAELRDDLAG----VPVPYYRTSADVMARVVGFHLNRGV
MLBr_02140|M.leprae_Br4923 SPVSLS----QLSALTTLANEG----------------------AMTPGA
* :: :* * :. *.
Mflv_1715|M.gilvum_PYR-GCK LASASRAPELTVAEVLDGARTVAVLEGVNDHENLGSVFRNAAGLGVDAVI
Mvan_5036|M.vanbaalenii_PYR-1 LASASRAPELTVPHVLDGARTVAVLEGVNDHENLGSVFRNAAGLGVDGVI
TH_1372|M.thermoresistible__bu LASAARPTELTVPQVLDGARTVAVLEGVNDHENLGSIFRNAAGLGVDAVI
MSMEG_5687|M.smegmatis_MC2_155 LASAPRAAELTVDDVIADARTIAVLEGVNDHENLGSIFRNAAGLAVDAVI
MAB_0881|M.abscessus_ATCC_1997 LAASRRPEELPAADLLQTARTVAVLEGVNDHENLGSIFRNAAGMGVDAVL
Mb0905|M.bovis_AF2122/97 LAAARRVPEPSVAQVVAGARTVAVLEGVNDHENLGSIFRNAAGLSVDAVV
Rv0881|M.tuberculosis_H37Rv LAAAGRVPEPSVAQVVAGARTVAVLEGVNDHENLGSIFRNAAGLSVDAVV
MMAR_4651|M.marinum_M LAAASRVVEPSVGQVVDGARTIAVLEGVNDHENLGSIFRNAAGLGVDAVI
MUL_0269|M.ulcerans_Agy99 LAAASRVVEPSVGQVVDGARTIAVLEGVNDHENLSSIFRNAAGLGVHAVI
MAV_1009|M.avium_104 LAAARRVPEPGVAELLAGSRTVAVLEGVNDHENLGAIFRNAAGLGVDAVI
MLBr_02140|M.leprae_Br4923 LAIRERVRPPSMTRVIASLADMGFVDRE----------------------
** * :: :..::
Mflv_1715|M.gilvum_PYR-GCK FGSGCADPLYRRAVRVSMGHALLVPFARAANWPADLNILRDNDFRLLAMT
Mvan_5036|M.vanbaalenii_PYR-1 FGSGCADPLYRRAVRVSMGHALLVPFAKAANWPGDLELLRDQGFRLLAMT
TH_1372|M.thermoresistible__bu FGSGCADPLYRRAVRVSMGHALLVPYARARHWPADLRLLRDNGFQLLAMT
MSMEG_5687|M.smegmatis_MC2_155 FGAGCADPLYRRAVRVSMGHALLVPFARASSWPTDLELLRDKGFRLLAMT
MAB_0881|M.abscessus_ATCC_1997 FGSGCADPLYRRAVRVSMGHALLVPFARLPEWPKSLYRLRDSGFRLLAMT
Mb0905|M.bovis_AF2122/97 FGTGCADPLYRRAVRVSMGHALLVPYARAADWPTELMTLKESGFRLLAMT
Rv0881|M.tuberculosis_H37Rv FGTGCADPLYRRAVRVSMGHALLVPYARAADWPTELMTLKESGFRLLAMT
MMAR_4651|M.marinum_M FGSGCADPLYRRAVRVSMGHALLVPYARATDWPAELVALKERGFRLLALT
MUL_0269|M.ulcerans_Agy99 FGSGCADPLYRRAVRVSMGHALLVPYARATDWPAELVALKERGFRLLALT
MAV_1009|M.avium_104 FGSGCADPLYRRAVRVSMGHALLVPYARATDWPAELKTLKEKGFRLLAMT
MLBr_02140|M.leprae_Br4923 -----PHPVDGRQVLVSVS---------------------QSGAELVKAA
..*: * * **:. : . .*: :
Mflv_1715|M.gilvum_PYR-GCK PDPTVPTLADAVSGLTEERIAILVGAEGPGLKEHTMRSADVRVRIPMARG
Mvan_5036|M.vanbaalenii_PYR-1 PDPTVQTLAQAMSGLAEQRVAILVGAEGPGLKEHTMRASDVRVRIPMSRG
TH_1372|M.thermoresistible__bu PNPKAETLAAVMPRLAAQKVAVLVGAEGPGLAESTMRAADVRVRIPMSRG
MSMEG_5687|M.smegmatis_MC2_155 PDPSAATLSDAMVQLEGDRVAILVGAEGPGLTERTMRASDVRVRIPMSRG
MAB_0881|M.abscessus_ATCC_1997 PAGDSKALADAIPPLRAEKVALMVGAEGPGLTDVALRASDLRVRIPMANG
Mb0905|M.bovis_AF2122/97 PHGNACKLPEAIAAVSHERIALLVGAEGPGLTAAALRISDVRVRIPMSRG
Rv0881|M.tuberculosis_H37Rv PHGNACKLPEAIAAVSHERIALLVGAEGPGLTAAALRISDVRVRIPMSRG
MMAR_4651|M.marinum_M PKGDARALPEAMDAVGDQPVALLVGAEGPGLTAAALRISDLRVRIPMSRG
MUL_0269|M.ulcerans_Agy99 PKGDARALPEAMDAVGDQPVALLVGAEGPGLTAAALRISDLRVRIPMSRG
MAV_1009|M.avium_104 PQGSACGLAEAMTAARGDRVAVLVGAEGPGLTPAALRLSDVRVRIPMSRG
MLBr_02140|M.leprae_Br4923 RRARQEWLVERLMTLNSDKRDILRNAADLILELIDESP------------
* : : :: .* . *
Mflv_1715|M.gilvum_PYR-GCK TDSLNVATAAALAFYERDRSHR--------------
Mvan_5036|M.vanbaalenii_PYR-1 TDSLNVATAAALAFYERDRLGR--------------
TH_1372|M.thermoresistible__bu TDSLNVATAAALAFYERSRPSG--------------
MSMEG_5687|M.smegmatis_MC2_155 TDSLNVATAAALAFYERARLSH--------------
MAB_0881|M.abscessus_ATCC_1997 TDSLNVATAAALAFYERARLAP--------------
Mb0905|M.bovis_AF2122/97 TDSLNVATAAALAFYERTRSGHHIGPGT--------
Rv0881|M.tuberculosis_H37Rv TDSLNVATAAALAFYERTRSGHHIGPGT--------
MMAR_4651|M.marinum_M TDSLNVATAAALAFYERARLGQ--------------
MUL_0269|M.ulcerans_Agy99 TDSLNVATAAALAFYERARLGQ--------------
MAV_1009|M.avium_104 TDSLNVATAAALAFYERSRPVGGHRAAAGGGDGQSG
MLBr_02140|M.leprae_Br4923 ------------------------------------