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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_1234 | - | - | 100% (460) | metallo-beta-lactamase family protein |
| M. thermoresistible (build 8) | TH_1873 | - | 3e-14 | 29.22% (219) | POSSIBLE GLYOXALASE II (HYDROXYACYLGLUTATHIONE HYDROLASE) (GLX |
| M. thermoresistible (build 8) | TH_1580 | - | 8e-14 | 25.53% (188) | CONSERVED HYPOTHETICAL PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0651c | - | 7e-15 | 28.44% (218) | glyoxalase II |
| M. gilvum PYR-GCK | Mflv_0985 | - | 0.0 | 84.75% (459) | beta-lactamase domain-containing protein |
| M. tuberculosis H37Rv | Rv0634c | - | 7e-15 | 28.44% (218) | glyoxalase II |
| M. leprae Br4923 | MLBr_01912 | - | 4e-14 | 30.32% (221) | putative glyoxylase II |
| M. abscessus ATCC 19977 | MAB_0121 | - | 1e-13 | 49.37% (79) | rhodanese-like protein |
| M. marinum M | MMAR_2442 | - | 3e-16 | 27.13% (188) | hypothetical protein MMAR_2442 |
| M. avium 104 | MAV_4532 | - | 6e-16 | 29.86% (221) | metallo-beta-lactamase family protein |
| M. smegmatis MC2 155 | MSMEG_5385 | - | 0.0 | 84.25% (457) | metallo-beta-lactamase family protein |
| M. ulcerans Agy99 | MUL_1621 | - | 4e-16 | 27.72% (184) | hypothetical protein MUL_1621 |
| M. vanbaalenii PYR-1 | Mvan_4023 | - | 0.0 | 84.53% (459) | beta-lactamase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0651c|M.bovis_AF2122/97 --------------------------------------------------
Rv0634c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4532|M.avium_104 --------------------------------------------------
MLBr_01912|M.leprae_Br4923 --------------------------------------------------
Mflv_0985|M.gilvum_PYR-GCK MKFIQYYLDCLSHASYLIADETTGRAVVVDPQRDVAEYLSDAEEFGYTIE
Mvan_4023|M.vanbaalenii_PYR-1 MKFIQYYLDCLSHASYLIADETTGRAVVVDPQRDVAEYLADATEFGYTIE
MSMEG_5385|M.smegmatis_MC2_155 MKFTQYYLDCLSHASYLIADETTGRAVVVDPQRDVAGYLADAEEFGYTIE
TH_1234|M.thermoresistible__bu MKFIQYYLDCLSHASYLIADDKTGRAVVVDPQRDVAEYLSDAEKYGYTIE
MAB_0121|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2442|M.marinum_M --------------------------------------------------
MUL_1621|M.ulcerans_Agy99 --------------------------------------------------
Mb0651c|M.bovis_AF2122/97 --------------------------------------------------
Rv0634c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4532|M.avium_104 --------------------------------------------------
MLBr_01912|M.leprae_Br4923 --------------------------------------------------
Mflv_0985|M.gilvum_PYR-GCK LVIETHFHADFLSGHLELAEATGAKIVYSSVAETEFESMGVADGERYSLG
Mvan_4023|M.vanbaalenii_PYR-1 LVIETHFHADFLSGHLELAKATGAKIVYSSVAETEFESMGVADGQIYSLG
MSMEG_5385|M.smegmatis_MC2_155 LVIETHFHADFLSGHLELAKATGAKIVYSSVAETEFESMGVADGERYSLG
TH_1234|M.thermoresistible__bu LVIETHFHADFLSGHLELAEATGAKIVYSSVAETEFESMGVADGERYSLG
MAB_0121|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2442|M.marinum_M --------------------------------------------------
MUL_1621|M.ulcerans_Agy99 --------------------------------------------------
Mb0651c|M.bovis_AF2122/97 ---------------------MSK-DRLYFRQLLSGRDFAVGDMFATQMR
Rv0634c|M.tuberculosis_H37Rv ---------------------MSK-DRLYFRQLLSGRDFAVGDMFATQMR
MAV_4532|M.avium_104 ---------------------MSD-DRLYFRQLLSGRDFAAGDMFATQMR
MLBr_01912|M.leprae_Br4923 ---------------------MSDSDRLYFRQLLSGRDFAVDDVVATQMR
Mflv_0985|M.gilvum_PYR-GCK DVTLEFRHTPGHTPESMSIVVYEHADDQVPYGVLTGDALFIGDVGRPDLL
Mvan_4023|M.vanbaalenii_PYR-1 EVTLKFLHTPGHTPESLSIVVYEHAGDEVPYGVLTGDALFIGDVGRPDLL
MSMEG_5385|M.smegmatis_MC2_155 EVTLEFRHTPGHTPESMSVVVYEHSNDDVPYGVLTGDALFIGDVGRPDLL
TH_1234|M.thermoresistible__bu DVTLEFLHTPGHTPESLSIVVYEHADDEIPYGVLTGDTLFIGDVGRPDLL
MAB_0121|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2442|M.marinum_M ---------------------MTVVDDNYTGHVDPGTVARRTLPGATILK
MUL_1621|M.ulcerans_Agy99 ---------------------MTVVDDNYTGHVDPGTVARRTLPGATILK
Mb0651c|M.bovis_AF2122/97 NFAYLIGDRTTG--------------DCVVVDPAYAAG------------
Rv0634c|M.tuberculosis_H37Rv NFAYLIGDRTTG--------------DCVVVDPAYAAG------------
MAV_4532|M.avium_104 NFAYLIGDRQTG--------------DCVVVDPAYAAS------------
MLBr_01912|M.leprae_Br4923 NFAYLIGDRQTG--------------DCVVVDPAYAAG------------
Mflv_0985|M.gilvum_PYR-GCK ASIGFTREELAEKLYDSLHNKLMTLPDATRVYPAHGAGSACGKNLSTDLW
Mvan_4023|M.vanbaalenii_PYR-1 ASIGFTREELADKLYDSLHTKLMTLPDATRVYPAHGAGSACGKNLSTDLW
MSMEG_5385|M.smegmatis_MC2_155 ASIGFTREELAEKLYDSLRNKLMTLPDATRVYPAHGAGSACGKNLSTERW
TH_1234|M.thermoresistible__bu ASIGYTREELADKLYDSLHHKLMTLPDATRVYPAHGAGSACGKNLSTELW
MAB_0121|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2442|M.marinum_M ASVGPMDN-------------------NAYLVTCSATG------------
MUL_1621|M.ulcerans_Agy99 ASVGPVDN-------------------NAYLVTCSATG------------
Mb0651c|M.bovis_AF2122/97 -------DLLDALESDDMQLSGVLVTHHHPDHVGGSMMGFQLPG-LAELL
Rv0634c|M.tuberculosis_H37Rv -------DLLDALESDDMQLSGVLVTHHHPDHVGGSMMGFQLPG-LAELL
MAV_4532|M.avium_104 -------DLLDTLEADGMHLSGVLVTHHHPDHVGGSMMGFTLAG-LAELV
MLBr_01912|M.leprae_Br4923 -------DLVDALEADGMRLSGVLVTHHHPDHVGGVMMGFQLKG-LTELL
Mflv_0985|M.gilvum_PYR-GCK STMGEQKETNYALRAPDKATFMALVTEGQPPAPSYFVYDAILNRKDRELL
Mvan_4023|M.vanbaalenii_PYR-1 STMGEQKATNYALRAPDKATFMELVTEGQPPAPSYFVYDAILNRKDRELL
MSMEG_5385|M.smegmatis_MC2_155 STIGEQKQTNYALRAPDLATFMALVTAGQPAAPSYFVYDAILNRKDRDLL
TH_1234|M.thermoresistible__bu STIGEQRETNYALRAPDKATFIELVTEGQPPAPGYFVYDAILNRKNRGLL
MAB_0121|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2442|M.marinum_M -------QTLLIDAANDAEVLIDLIRRYAP----KIALIVTSHQHFDHWQ
MUL_1621|M.ulcerans_Agy99 -------QTLLIDAANDAEVLIDLIRRYAP----KIALIVTSHQHFDHWQ
Mb0651c|M.bovis_AF2122/97 ERASVPVHVNTHEALWVSRVTGIPVGDLITHEHGDK--------------
Rv0634c|M.tuberculosis_H37Rv ERASVPVHVNTHEALWVSRVTGIPVGDLITHEHGDK--------------
MAV_4532|M.avium_104 ERAPVPVHVNSHEALWVSRVTGISASDLTAHENHDK--------------
MLBr_01912|M.leprae_Br4923 ERVTVPVHVNTHEALWISRVTGIDIGHLTTHEHRDK--------------
Mflv_0985|M.gilvum_PYR-GCK DQTKMPAAMTYEQVRDAMAAGAILVDGRGPEEFATGHLRGAVNIGLAGRY
Mvan_4023|M.vanbaalenii_PYR-1 DETKMPEAMSYEQVRDAVKAGAVLVDGRNPEEFALGHLRGAVNIGLEGRY
MSMEG_5385|M.smegmatis_MC2_155 DETEIPAAMRYEQVNQALRDGAILVDGRSPEEFATGHLRQAINIGLQGRY
TH_1234|M.thermoresistible__bu DETALPPVLSYDEMLAAVERGAVLVDGRSPEEFAQGHLRGAINIGLDGRY
MAB_0121|M.abscessus_ATCC_1997 ------------------------------MSFPTG--------------
MMAR_2442|M.marinum_M ALQAVAEATGAPTAAHEIDAEPLPVKPDRLLANGDR--------------
MUL_1621|M.ulcerans_Agy99 ALQAVAEATGAPTAAHEIDAEPLPVKPDRLLANGDR--------------
Mb0651c|M.bovis_AF2122/97 ---------------------------VSVGDIDIELLHTP---------
Rv0634c|M.tuberculosis_H37Rv ---------------------------VSVGDIDIELLHTP---------
MAV_4532|M.avium_104 ---------------------------VSIGDIEIELLHTP---------
MLBr_01912|M.leprae_Br4923 ---------------------------LSVGDIEIELLHTP---------
Mflv_0985|M.gilvum_PYR-GCK AEFAGSVVPTDVDIVLFTEPGQELEGKNRLARIGFDRVVGYLDRPFEVMF
Mvan_4023|M.vanbaalenii_PYR-1 AEFAGSVVPTDVDIVLFTEPGQELEGKTRLARIGFDRVIGYLERPFEAML
MSMEG_5385|M.smegmatis_MC2_155 AEFAGSVVPADVDIVLFTEPGEELEAKNRLARIGFDRVIGHLDRPFEVML
TH_1234|M.thermoresistible__bu AEFAGSVLPADVDIVLFTEPGDELEAKNRLARIGFDRVIGHLDRPFEVMM
MAB_0121|M.abscessus_ATCC_1997 ---------------------------DDVPQVGIDEIS-----------
MMAR_2442|M.marinum_M ---------------------------VQIGELSFDVIHLR---------
MUL_1621|M.ulcerans_Agy99 ---------------------------VQIGELSFDVIHLR---------
: : :: :
Mb0651c|M.bovis_AF2122/97 ------------------GHTPGSQCFLLDGRLVAGDTLFLEGCGRTDFP
Rv0634c|M.tuberculosis_H37Rv ------------------GHTPGSQCFLLDGRLVAGDTLFLEGCGRTDFP
MAV_4532|M.avium_104 ------------------GHTPGSQCFLLDGRLVAGDTLFLEGCGRTDFP
MLBr_01912|M.leprae_Br4923 ------------------GHTPGSQCFLLDGLLVAGDTLFLEGCGRTDFP
Mflv_0985|M.gilvum_PYR-GCK THPGDVQMASRLTAKAFDQRAAEVADLQIVDVRNPGEVAAGTIPNAITIP
Mvan_4023|M.vanbaalenii_PYR-1 DHQDEVQVASRLTAKAFDARAAELADLQIVDVRNPGEVAAGMIPDAVSIP
MSMEG_5385|M.smegmatis_MC2_155 AHPDDVQMASRLTATAFDQRTAEVADLQIVDVRNPGEVADGAIPHAITIP
TH_1234|M.thermoresistible__bu AHPDRVQVASRLTVKAFDQRAAELPDLQIVDVRNPGEVALGAIPGAIAIP
MAB_0121|M.abscessus_ATCC_1997 --------------------AALSLGVKLLDVREDDEWAAGHIEGAQHIP
MMAR_2442|M.marinum_M ------------------GHTPGSIALALDGAATGG--VTQLFTGDCLFP
MUL_1621|M.ulcerans_Agy99 ------------------GHTPGSIALALDGAATGG--VTQLFTGDCLFP
:. . : . . :*
Mb0651c|M.bovis_AF2122/97 GGDSDEMYRSLRQLAELPGDPTVFPGHWYSAEPSASLSEVKRSNYVYRPA
Rv0634c|M.tuberculosis_H37Rv GGDSDEMYRSLRQLAELPGDPTVFPGHWYSAEPSASLSEVKRSNYVYRPA
MAV_4532|M.avium_104 GGDSDEMYRSLQRLAKLPGDPTVFPGHWYSAEPSASLSEVKRSNYVYRAS
MLBr_01912|M.leprae_Br4923 GGNSDEMYRSLQQLAQLPGNPTVFPGHWYSTAPSATLSMVKCSNYVYRAA
Mflv_0985|M.gilvum_PYR-GCK VG---QLPARLGELDPAKPTVVYCAGGYRSSVAASLLRGNGFTDVSDILG
Mvan_4023|M.vanbaalenii_PYR-1 VG---QLPARLGELDPAKPTVVYCAGGYRSSVAASLLRAHGFADVSDILG
MSMEG_5385|M.smegmatis_MC2_155 VG---QLPARLGELDPAKPTVVYCAGGYRSSVAASVLRRNGFADVSDILG
TH_1234|M.thermoresistible__bu VG---QLPDRLTELDPTRPTVVYCAGGYRSSVAASLLRRSGFTDVSDILG
MAB_0121|M.abscessus_ATCC_1997 LG---DVPSRMDELDPDAPLWVICHAGGRSQRAAAYLNRNGF-DVSNVSG
MMAR_2442|M.marinum_M GG--VGKTWQPGDFTQLVEDVSSRVFDVYPDSTVVYPGHGDDTVLGVERP
MUL_1621|M.ulcerans_Agy99 GG--VGKTWQPGDFTQLVEDVSSRVFNVYPDSTVVYPGHGDDTALGFERP
* : . .
Mb0651c|M.bovis_AF2122/97 SLDQWRMLMGG---
Rv0634c|M.tuberculosis_H37Rv SLDQWRMLMGG---
MAV_4532|M.avium_104 DLDQWRMLMGG---
MLBr_01912|M.leprae_Br4923 DLNQWRMLMDS---
Mflv_0985|M.gilvum_PYR-GCK GFGAWEETHQNA--
Mvan_4023|M.vanbaalenii_PYR-1 GYGAWDEAHQNA--
MSMEG_5385|M.smegmatis_MC2_155 GYGAWRDARQGV--
TH_1234|M.thermoresistible__bu GYGAWVDARQVA--
MAB_0121|M.abscessus_ATCC_1997 GMLAWVQAGKPTIS
MMAR_2442|M.marinum_M HLDEWRERGW----
MUL_1621|M.ulcerans_Agy99 HLDEWRERGW----
*