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M. thermoresistible (build 8) TH_0899 (-)

annotation: hydrolase, alpha/beta fold family protein, putative
coordinates: 1807588 - 1808439
length: 284

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0899--100% (284)hydrolase, alpha/beta fold family protein, putative
M. thermoresistible (build 8)TH_2963-2e-1936.44% (247) PUTATIVE putative 3-oxoadipate enol-lactonase
M. thermoresistible (build 8)TH_4528-7e-1727.99% (293) PUTATIVE alpha/beta hydrolase fold

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3600cbphD2e-1428.83% (281) 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD
M. gilvum PYR-GCKMflv_2414-1e-12177.70% (269) alpha/beta hydrolase fold
M. tuberculosis H37RvRv3569cbphD2e-1428.83% (281) 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD
M. leprae Br4923MLBr_02269-5e-1126.88% (279) putative hydrolase
M. abscessus ATCC 19977MAB_3810-1e-1727.76% (299) putative hydrolase, alpha/beta fold
M. marinum MMMAR_4771-1e-10667.16% (271) hypothetical protein MMAR_4771
M. avium 104MAV_0884-1e-11976.87% (268) hydrolase, alpha/beta fold family protein, putative
M. smegmatis MC2 155MSMEG_4860-1e-12077.90% (276) hydrolase, alpha/beta fold family protein, putative
M. ulcerans Agy99MUL_0342-1e-10667.53% (271) hypothetical protein MUL_0342
M. vanbaalenii PYR-1Mvan_4238-1e-11674.72% (269) alpha/beta hydrolase fold

CLUSTAL 2.0.9 multiple sequence alignment


TH_0899|M.thermoresistible__bu      ------VTFDRRT----IVVDG-LATSYLEAGS---GDPLVLLHGGEFGA
MSMEG_4860|M.smegmatis_MC2_155      ------MDFERKT----IVVDG-LTTAYLEAGDPA-RDAVVLLHGGEFGV
Mflv_2414|M.gilvum_PYR-GCK          ----MGVTFERNT----VLVEG-LTTSYLEAGQ---GDPIVLLHGGEFGA
Mvan_4238|M.vanbaalenii_PYR-1       ------MALEPKS----VLVDG-LRTSYLEAGH---GEPVVLLHGGEFGA
MMAR_4771|M.marinum_M               ------MRVHRRA----VAVDG-LPTSYLEAGD---GDPVVLLHGGEFGA
MUL_0342|M.ulcerans_Agy99           ------MRIHRRA----VAVDG-LATSYLEAGD---GDPVVLLHGGEFGA
MAV_0884|M.avium_104                ------MEIHRKT----MSVDG-LVTSYLEAGE---GDPVVLLHGGEFGA
Mb3600c|M.bovis_AF2122/97           MTATEELTFESTSRFAEVDVDGPLKLHYHEAG-VGNDQTVVLLHGGGPGA
Rv3569c|M.tuberculosis_H37Rv        MTATEELTFESTSRFAEVDVDGPLKLHYHEAG-VGNDQTVVLLHGGGPGA
MAB_3810|M.abscessus_ATCC_1997      ----MDVTYEGTKRELATDEG---TLRYHEAGTAGEGEPLILLHGSGPGV
MLBr_02269|M.leprae_Br4923          ----------------------MINLAYEDRGT---GEPVVFIAGRG-GA
                                                               * : *     :.:::: *   *.

TH_0899|M.thermoresistible__bu      SAELGWERNIDALAGYYRVIAPDMLGFGHSAKVIDFVDGRGMRIRHIARL
MSMEG_4860|M.smegmatis_MC2_155      SAELGWERTIGALATDHHVLAPDMLGFGGSAKVVDFTDGRGMRIRHIARF
Mflv_2414|M.gilvum_PYR-GCK          DAALGWEATIDALASRYRVLAPDMLGFGGSAKVVDFTDGRGMRIRHIARF
Mvan_4238|M.vanbaalenii_PYR-1       SARIGWEHTIAPLAQRYRVLAPDMLGFGDSAKVVDFTDGRGMRIRHIARF
MMAR_4771|M.marinum_M               NAEIAWEHNIGVLGGRFRVLAPDLLGFGQSAKVVDFVDGRGMRIRHVARF
MUL_0342|M.ulcerans_Agy99           NAEIAWEHNIGVLGGRFRVLAPDLLGFGQSAKVVDFVDGRGMRIRHVARF
MAV_0884|M.avium_104                SAELGWERNIAALAARYRVLAPDQLGFGGSAKVIDFVDGRGMRIRHVARF
Mb3600c|M.bovis_AF2122/97           ASWTNFSRNIAVLARHFHVLAVDQPGYGHSDKRAEHGQFNRYAAMALKGL
Rv3569c|M.tuberculosis_H37Rv        ASWTNFSRNIAVLARHFHVLAVDQPGYGHSDKRAEHGQFNRYAAMALKGL
MAB_3810|M.abscessus_ATCC_1997      TGWRNYRGNLGVFAKHFHTYVLEFPGFGVSDAVPGHPVLT--AGASVIRF
MLBr_02269|M.leprae_Br4923          GRTWQPHQVPAFLAAGYRVITFDNRGIGATENTEGFTTQT--MVADTAVL
                                                :.  .:. . :  * * :     .             :

TH_0899|M.thermoresistible__bu      CALLGIESAHFVGNSMG---AINLLVDATSPAPRLPMRSLVAICG---GG
MSMEG_4860|M.smegmatis_MC2_155      CAQMGVKSAHFVGNSMG---AINLLVDTTSDAPLLPVRSLVAICG---GG
Mflv_2414|M.gilvum_PYR-GCK          CDVMGIAAAHFVGNSMG---AINLLVDATSDTPVLPMRSLVAVCG---GG
Mvan_4238|M.vanbaalenii_PYR-1       CEVMDVEAAHFVGNSMG---AINLLVDVTSDAAVLPVRSLVLICG---GG
MMAR_4771|M.marinum_M               CDVLGVDSAHFVGNSMG---AIMLLTDTTSDAPMLPVQTMALICG---GG
MUL_0342|M.ulcerans_Agy99           CDVLGVGSAHFVGNSMG---AIMLLTDTTSDAPMLPVRTMALICG---GG
MAV_0884|M.avium_104                CELLGVESAHFVGNSMG---AINLLTDATSDSPLWPVRSAVIICG---GG
Mb3600c|M.bovis_AF2122/97           FDQLGLGRVPLVGNSLGGGTAVRFALDYPARAGRLVLMGPGGLSINLFAP
Rv3569c|M.tuberculosis_H37Rv        FDQLGLGRVPLVGNSLGGGTAVRFALDYPARAGRLVLMGPGGLSINLFAP
MAB_3810|M.abscessus_ATCC_1997      MDGLGISSAAVVGNSMGGVVGINLAIKHPDRITKLVTIG--GVGPNIFSP
MLBr_02269|M.leprae_Br4923          IESLGAVPARIVGVSMG-----SFIAQELMVARPELVRAAVLMAT---RG
                                       :.   . .** *:*      :  .               :       

TH_0899|M.thermoresistible__bu      EIQRNEHMAALYDYDATEPAMRRIVTALFFDPAFPADDAYVRRRYESSIL
MSMEG_4860|M.smegmatis_MC2_155      EIQRNEHMAALYDYDATLEGMRRIVAALFADPSYPADEDYVRRRYESSIA
Mflv_2414|M.gilvum_PYR-GCK          DIQRNEHVSALYDYDATLEGMRRIVTALFADPSYPADDEYVRRRYESSIA
Mvan_4238|M.vanbaalenii_PYR-1       EIQRNEHVDALYDYDATFEGMRRIVAALFADPAYPTDDEYVRRRYESSIA
MMAR_4771|M.marinum_M               QIQQNSHFDALQSYDATLPAMRRIVAALFHDARYPADMDYVQRRYDSSIA
MUL_0342|M.ulcerans_Agy99           QIQQNSHFDALQSYDATLPAMRRIVAALFHDARYPADMDYVQRRYDSSIA
MAV_0884|M.avium_104                EIQQNEYFEALQNYDATLPAMRRIVEALFFDPAYPADDDYVRRRHESSTA
Mb3600c|M.bovis_AF2122/97           DPTEGVKRLSKFSVAPTRENLEAFLRVMVYDKNLITP-ELVDQRFALAST
Rv3569c|M.tuberculosis_H37Rv        DPTEGVKRLSKFSVAPTRENLEAFLRVMVYDKNLITP-ELVDQRFALAST
MAB_3810|M.abscessus_ATCC_1997      SPSEGLRLLQEFTDNPDRDKLIRWLNSMVWDPAVVTD-ELIEERWEAAIN
MLBr_02269|M.leprae_Br4923          RLDRTRQFFHAAEAEFHDSGIQLPSG---YNAKVRLLENLSRKTLNDDVA
                                       .                :         :           .       

TH_0899|M.thermoresistible__bu      PGAWETLAAARFRRPGLE------PPAAPSAARAYHRIGVPTLIVEGAGD
MSMEG_4860|M.smegmatis_MC2_155      PGAWEALAAARFRRPGLE------PPAAPSSARAYERIGVPVLIVEGERD
Mflv_2414|M.gilvum_PYR-GCK          PGAWESLAAARFRRPGLE------PPPTPSSSRAYERITVPTLVVEGGAD
Mvan_4238|M.vanbaalenii_PYR-1       PGAWESLAAARFRRPGLD------PPATPSSARAYDRITVPTLVLEGRDD
MMAR_4771|M.marinum_M               PGAWEAVAAARFRRPGAP------PSATPSSSRRYDRITVPTMLVEGRND
MUL_0342|M.ulcerans_Agy99           PGAWEAVAAARFRRPGAP------PSATPSSSRRYDRITVPTMLVEGRND
MAV_0884|M.avium_104                PGAWEAIAAARFRRPGAT------PSPTPSSARAYERIGVPTLVVEGRGD
Mb3600c|M.bovis_AF2122/97           PESLTATRAMG--KSFAG-----ADFEAGMMWREVYRLRQPVLLIWGRED
Rv3569c|M.tuberculosis_H37Rv        PESLTATRAMG--KSFAG-----ADFEAGMMWREVYRLRQPVLLIWGRED
MAB_3810|M.abscessus_ATCC_1997      PDAHKTAQLMYGSKAFAMQQQFLANADIPPYWAMMHKIKCPTLLTWGRDD
MLBr_02269|M.leprae_Br4923          VADWIAMFNMWPIKSTPGLRCQTDVAPQNNRLPAYRSIAAPVLVIGFAED
                                         :       :.                      :  *.::     *

TH_0899|M.thermoresistible__bu      KLLPPGWAADIAAQIPDARSAVIADAGHCPQIEQPAAVNELLLDFLTTVN
MSMEG_4860|M.smegmatis_MC2_155      KLLPSGWAAQIAAQISGATSTVVADAGHCPQIEQPDTVNRLLSDFLKEVS
Mflv_2414|M.gilvum_PYR-GCK          KLLPRGWAAEIAGQIAGARSAVIDEAGHCPQIEQPEAVIGLLLTFFEEQR
Mvan_4238|M.vanbaalenii_PYR-1       KLLPTGWAAEIAGQIRHGRSAVIDDAGHCPQIEQPAAVNQELLDFFEEQT
MMAR_4771|M.marinum_M               KLLPSGWGEQIAGQIRNGHSQVVDRAGHCPQIEQAGTVNELMLDFLTR--
MUL_0342|M.ulcerans_Agy99           KLLPSGWGEQIAGQIRNGHSQVVDRAGHCPQIEQAGTVNELMLDFLSR--
MAV_0884|M.avium_104                KLLPAGWSAQIAKQIDGARSVVVDDAGHCPQIEQPSVVNQLLMDFLATA-
Mb3600c|M.bovis_AF2122/97           RVNPLDGALVALKTIPRAQLHVFGQCGHWVQVEKFDEFNKLTIEFLGGGR
Rv3569c|M.tuberculosis_H37Rv        RVNPLDGALVALKTIPRAQLHVFGQCGHWVQVEKFDEFNKLTIEFLGGGR
MAB_3810|M.abscessus_ATCC_1997      RVSPPDMAIVPMRLIPNAELHIFPNSGHWVMIEAKQAFEQTVVDFLRR--
MLBr_02269|M.leprae_Br4923          VVTPPSLGREVADVLPNGRYLQIPDAGHLGFFERPEAVNAAALQFFAGVK
                                     : * . .      :  .    .  .**   .*    .      *:    

TH_0899|M.thermoresistible__bu      TRDREVATR
MSMEG_4860|M.smegmatis_MC2_155      ---------
Mflv_2414|M.gilvum_PYR-GCK          ---------
Mvan_4238|M.vanbaalenii_PYR-1       ---------
MMAR_4771|M.marinum_M               ---------
MUL_0342|M.ulcerans_Agy99           ---------
MAV_0884|M.avium_104                ---------
Mb3600c|M.bovis_AF2122/97           ---------
Rv3569c|M.tuberculosis_H37Rv        ---------
MAB_3810|M.abscessus_ATCC_1997      ---------
MLBr_02269|M.leprae_Br4923          GEWP-----