For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_0227 (hypD)

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0227	hypD	-	100% (382)	hydrogenase expression/formation protein HypD
M. thermoresistible (build 8)	TH_1942	hypD	0.0	84.35% (377)	hydrogenase expression/formation protein HypD

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	Mflv_3981	-	1e-105	50.95% (367)	hydrogenase expression/formation protein HypD
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	-	-	-	-	-
M. marinum M	MMAR_1857	hypD	0.0	85.83% (381)	hydrogenase-forming protein, HypD
M. avium 104	-	-	-	-	-
M. smegmatis MC2 155	MSMEG_2702	hypD	0.0	82.13% (375)	hydrogenase expression/formation protein HypD
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	Mvan_2361	-	1e-106	52.02% (371)	hydrogenase expression/formation protein HypD

CLUSTAL 2.0.9 multiple sequence alignment


TH_0227|M.thermoresistible__bu      MRFVDEFRDPAAARKLLAAIEVLAAG-GEDGAPFKFMEVCGGHTHTIYRH
MMAR_1857|M.marinum_M               MKFVDEFRDPAAARKLLTAIEHLAHQPGAGPEHFKFMEVCGGHTHTIYRH
MSMEG_2702|M.smegmatis_MC2_155      MKFVDEYRDPAAARALVRSITELAAG-----DEFKFMEVCGGHTHTIYRH
Mflv_3981|M.gilvum_PYR-GCK          MKYLDEFSNPELAHRLIEQIEAVATR------RWSIMEVCGGQTHSIIRH
Mvan_2361|M.vanbaalenii_PYR-1       MRYLDEFRDPAAAAVLVDAIRRRATK------PWTVMEVCGGQTHSIIRN
                                    *:::**: :*  *  *:  *   *         :..******:**:* *:

TH_0227|M.thermoresistible__bu      GIEHLLPPTVELVHGPGCPVCVIPMGRIDDAMWLAAQPDVIFTSFGDMMR
MMAR_1857|M.marinum_M               GIEHLLPDNVELVHGPGCPVCVIPMGRIDDAMWLAGQPDVIFTCFGDMMR
MSMEG_2702|M.smegmatis_MC2_155      GIEHLLPESIELVHGPGCPVCVIPMGRVDDAMWLAEQPGVIFTTFGDMMR
Mflv_3981|M.gilvum_PYR-GCK          GIDQLLPDTVEMIHGPGCPVCVTPLEIIDKALDIASRPEVIFCSFGDMLR
Mvan_2361|M.vanbaalenii_PYR-1       GIDQLLAGAVEFIHGPGCPVCVTPLEMIDRALAIAARPDVIFCSFGDMLR
                                    **::**.  :*::********* *:  :* *: :* :* ***  ****:*

TH_0227|M.thermoresistible__bu      VPGSNGSLLDAKARGADVRFVYSPLDALKIAVDNPDKRVVYFAIGFETTA
MMAR_1857|M.marinum_M               VPGSDGSLLDAKARGADVRFVYSPLDALKVAIDNPDKQVVFFAIGFETTA
MSMEG_2702|M.smegmatis_MC2_155      VPGSAGNLIEAKARGADVRFVYSPLDALKIARDNPERHVVFFAVGFETTA
Mflv_3981|M.gilvum_PYR-GCK          VPGSEKDLFRVKSEGADVRVVYSPLDALTIARDNPDRQVVFFGIGFETTA
Mvan_2361|M.vanbaalenii_PYR-1       VPGSSQDLFGVRARGGDVRIVYSPLDATRIAADNPDKQVVFFGVGFETTA
                                    ****  .*: .::.*.***.*******  :* ***:::**:*.:******

TH_0227|M.thermoresistible__bu      PSTAVTLLRATELGLRNFSVFCNHVTIVPPIKAILESPDLRLSGFLGPGH
MMAR_1857|M.marinum_M               PSTAVTLVRARDLELPNFSVFCNHVTIVPPIKAILESPDLRLSGFIGPGH
MSMEG_2702|M.smegmatis_MC2_155      PSTAVTLVGARALGVRNFSVFCNHVTIVPPIKAILESPDLRLSGFLGPGH
Mflv_3981|M.gilvum_PYR-GCK          PANAMTVYQAKKLGIENFSLLVSHVLVPPAIAAIMESPTCRVQAFLAAGH
Mvan_2361|M.vanbaalenii_PYR-1       PANAMAVLHAQRLGLTNFSMLVSHVLVPPAMTAILSSPTNRVQGFLAAGH
                                    *:.*:::  *  * : ***:: .** : *.: **:.**  *:..*:..**

TH_0227|M.thermoresistible__bu      VSTVVGIRPYRFVPEVYRKPLVVAGFEPLDILAAVAMLLRQIREGRCEVE
MMAR_1857|M.marinum_M               VSTVVGNRPYRFVPEVYHKPLVVAGFEPLDILASVTMLLRQIREGRCEVE
MSMEG_2702|M.smegmatis_MC2_155      VSTVVGLRPYRFVPGVYGKPIVVAGFEPLDILASVHMLLQQIRDGRCEVE
Mflv_3981|M.gilvum_PYR-GCK          VCTVMGTDEYPPLCDKYGTPIVVTGFEPLDILEGIRRTVIQLEAGRHELE
Mvan_2361|M.vanbaalenii_PYR-1       VCSVMGTSEYEPLVTEFGVPIVVTGFEPLDLLEGVRQVVELLEEGTPALR
                                    *.:*:*   *  :   :  *:**:******:* .:   :  :. *   :.

TH_0227|M.thermoresistible__bu      NQYSRIVAPQGNPAALGMLARVFELRPHFEWRGLGFISQSALKLRDEFAD
MMAR_1857|M.marinum_M               NQYKRVVPEEGNPAALALMGKVFALRPHFEWRGLGFISQSALRLSDDFAE
MSMEG_2702|M.smegmatis_MC2_155      NQYTRVVRPEGNVAALKLMAETFELRPHFEWRGLGFISQSALKIHPDYAG
Mflv_3981|M.gilvum_PYR-GCK          NAYPRAVQDTGNPAAKAMLLDVFDVTDR-TWRGIGMIASSGWRLSPAYRH
Mvan_2361|M.vanbaalenii_PYR-1       NAYPRAVSAEGNLVAQKTLAEVFAVTDR-QWRGIGMIPRSGWTLSPRYAE
                                    * * * *   ** .*   :  .* :  :  ***:*:*. *.  :   :  

TH_0227|M.thermoresistible__bu      YDAERLFDMPGVRVADPKACQCGEVLKGVLRPWECKVFGTACTPETPIGT
MMAR_1857|M.marinum_M               FDAELRFAMPGVRVADPKACQCGEVLKGVLKPWECKVFGTACTPETPIGT
MSMEG_2702|M.smegmatis_MC2_155      YDAELIFDMPGVRVADPKACQCGEVLKGVIKPWECKVFGTACTPETPIGT
Mflv_3981|M.gilvum_PYR-GCK          FDAEHRFAATDLHNEESAICRSGEVLQGLIKPHECTAFGTSCTPRNPLGA
Mvan_2361|M.vanbaalenii_PYR-1       FDAERRFGVGHLQVAESSDCRSGEVLQGLLKPNECPAFGRTCTPRTPLGA
                                    :***  *    ::  :.  *:.****:*:::* ** .** :***..*:*:

TH_0227|M.thermoresistible__bu      CMVSSEGACAAYYNFGRLHRDAATLVGQAGRG
MMAR_1857|M.marinum_M               CMVSPEGACAAYYNFGRLHRDAVKLVGQSGRA
MSMEG_2702|M.smegmatis_MC2_155      CMVSPEGACAAYYNFGRLHRDTAQLLLRR---
Mflv_3981|M.gilvum_PYR-GCK          TMVSSEGACAAYYLYRRLEVT-HA--------
Mvan_2361|M.vanbaalenii_PYR-1       TMVSSEGACAAYYQFRRLETAAHA--------
                                     ***.******** : **.