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M. marinum M MMAR_1857 (hypD)

KFVDEFRDPAAARKLLTAIEHLAHQPGAGPEHFKFMEVCGGHTHTIYRHGIEHLLPDNVELVHGPGCPVC
VIPMGRIDDAMWLAGQPDVIFTCFGDMMRVPGSDGSLLDAKARGADVRFVYSPLDALKVAIDNPDKQVVF
FAIGFETTAPSTAVTLVRARDLELPNFSVFCNHVTIVPPIKAILESPDLRLSGFIGPGHVSTVVGNRPYR
FVPEVYHKPLVVAGFEPLDILASVTMLLRQIREGRCEVENQYKRVVPEEGNPAALALMGKVFALRPHFEW
RGLGFISQSALRLSDDFAEFDAELRFAMPGVRVADPKACQCGEVLKGVLKPWECKVFGTACTPETPIGTC
MVSPEGACAAYYNFGRLHRDAVKLVGQSGRA*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. marinum M	MMAR_1857	hypD	-	100% (382)	hydrogenase-forming protein, HypD

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	Mflv_3981	-	1e-106	51.63% (368)	hydrogenase expression/formation protein HypD
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	-	-	-	-	-
M. avium 104	-	-	-	-	-
M. smegmatis MC2 155	MSMEG_2702	hypD	0.0	82.45% (376)	hydrogenase expression/formation protein HypD
M. thermoresistible (build 8)	TH_0227	hypD	0.0	85.83% (381)	hydrogenase expression/formation protein HypD
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	Mvan_2405	-	1e-106	51.36% (368)	hydrogenase expression/formation protein HypD

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1857|M.marinum_M               MKFVDEFRDPAAARKLLTAIEHLAHQPGAGPEHFKFMEVCGGHTHTIYRH
TH_0227|M.thermoresistible__bu      MRFVDEFRDPAAARKLLAAIEVLAAG-GEDGAPFKFMEVCGGHTHTIYRH
MSMEG_2702|M.smegmatis_MC2_155      MKFVDEYRDPAAARALVRSITELAAG-----DEFKFMEVCGGHTHTIYRH
Mflv_3981|M.gilvum_PYR-GCK          MKYLDEFSNPELAHRLIEQIEAVATR------RWSIMEVCGGQTHSIIRH
Mvan_2405|M.vanbaalenii_PYR-1       MKYLDEFSNPELAARLIEQITSAATR------RWSIMEVCGGQTHSIIRH
                                    *:::**: :*  *  *:  *   *         :.:******:**:* **

MMAR_1857|M.marinum_M               GIEHLLPDNVELVHGPGCPVCVIPMGRIDDAMWLAGQPDVIFTCFGDMMR
TH_0227|M.thermoresistible__bu      GIEHLLPPTVELVHGPGCPVCVIPMGRIDDAMWLAAQPDVIFTSFGDMMR
MSMEG_2702|M.smegmatis_MC2_155      GIEHLLPESIELVHGPGCPVCVIPMGRVDDAMWLAEQPGVIFTTFGDMMR
Mflv_3981|M.gilvum_PYR-GCK          GIDQLLPDTVEMIHGPGCPVCVTPLEIIDKALDIASRPEVIFCSFGDMLR
Mvan_2405|M.vanbaalenii_PYR-1       GIDQLLPDTVEMIHGPGCPVCVTPLEIIDKALDIASRPDVVFCSFGDMLR
                                    **::*** .:*::********* *:  :*.*: :* :* *:*  ****:*

MMAR_1857|M.marinum_M               VPGSDGSLLDAKARGADVRFVYSPLDALKVAIDNPDKQVVFFAIGFETTA
TH_0227|M.thermoresistible__bu      VPGSNGSLLDAKARGADVRFVYSPLDALKIAVDNPDKRVVYFAIGFETTA
MSMEG_2702|M.smegmatis_MC2_155      VPGSAGNLIEAKARGADVRFVYSPLDALKIARDNPERHVVFFAVGFETTA
Mflv_3981|M.gilvum_PYR-GCK          VPGSEKDLFRVKSEGADVRVVYSPLDALTIARDNPDRQVVFFGIGFETTA
Mvan_2405|M.vanbaalenii_PYR-1       VPGSEKDLFRVKSEGGDVRVVYSPLDALTIAREHPDKQVVFFGIGFETTA
                                    ****  .*: .*:.*.***.********.:* ::*:::**:*.:******

MMAR_1857|M.marinum_M               PSTAVTLVRARDLELPNFSVFCNHVTIVPPIKAILESPDLRLSGFIGPGH
TH_0227|M.thermoresistible__bu      PSTAVTLLRATELGLRNFSVFCNHVTIVPPIKAILESPDLRLSGFLGPGH
MSMEG_2702|M.smegmatis_MC2_155      PSTAVTLVGARALGVRNFSVFCNHVTIVPPIKAILESPDLRLSGFLGPGH
Mflv_3981|M.gilvum_PYR-GCK          PANAMTVYQAKKLGIENFSLLVSHVLVPPAIAAIMESPTCRVQAFLAAGH
Mvan_2405|M.vanbaalenii_PYR-1       PANAMTVYQARRLGIDNFSLLVSHVLVPPAISAIMESPTCRVQAFLAAGH
                                    *:.*:*:  *  * : ***:: .** : *.* **:***  *:..*:..**

MMAR_1857|M.marinum_M               VSTVVGNRPYRFVPEVYHKPLVVAGFEPLDILASVTMLLRQIREGRCEVE
TH_0227|M.thermoresistible__bu      VSTVVGIRPYRFVPEVYRKPLVVAGFEPLDILAAVAMLLRQIREGRCEVE
MSMEG_2702|M.smegmatis_MC2_155      VSTVVGLRPYRFVPGVYGKPIVVAGFEPLDILASVHMLLQQIRDGRCEVE
Mflv_3981|M.gilvum_PYR-GCK          VCTVMGTDEYPPLCDKYGTPIVVTGFEPLDILEGIRRTVIQLEAGRHELE
Mvan_2405|M.vanbaalenii_PYR-1       VCAVMGTDEYPPLCDKYGIPIVVTGFEPLDILEGIRRTVVQLESGRHELE
                                    *.:*:*   *  :   *  *:**:******** .:   : *:. ** *:*

MMAR_1857|M.marinum_M               NQYKRVVPEEGNPAALALMGKVFALRPHFEWRGLGFISQSALRLSDDFAE
TH_0227|M.thermoresistible__bu      NQYSRIVAPQGNPAALGMLARVFELRPHFEWRGLGFISQSALKLRDEFAD
MSMEG_2702|M.smegmatis_MC2_155      NQYTRVVRPEGNVAALKLMAETFELRPHFEWRGLGFISQSALKIHPDYAG
Mflv_3981|M.gilvum_PYR-GCK          NAYPRAVQDTGNPAAKAMLLDVFDVTDR-TWRGIGMIASSGWRLSPAYRH
Mvan_2405|M.vanbaalenii_PYR-1       NAYPRAVREAGNPAAKAMLLDVFELTDR-AWRGIGVIPGSGWRLSHAYRD
                                    * * * *   ** **  ::  .* :  :  ***:*.*. *. ::   :  

MMAR_1857|M.marinum_M               FDAELRFAMPGVRVADPKACQCGEVLKGVLKPWECKVFGTACTPETPIGT
TH_0227|M.thermoresistible__bu      YDAERLFDMPGVRVADPKACQCGEVLKGVLRPWECKVFGTACTPETPIGT
MSMEG_2702|M.smegmatis_MC2_155      YDAELIFDMPGVRVADPKACQCGEVLKGVIKPWECKVFGTACTPETPIGT
Mflv_3981|M.gilvum_PYR-GCK          FDAEHRFAATDLHNEESAICRSGEVLQGLIKPHECTAFGTSCTPRNPLGA
Mvan_2405|M.vanbaalenii_PYR-1       YDAEQRFAVSDIHTEESAVCRSGEVLQGLIKPHECAAFGTVCTPRNPLGA
                                    :***  *  ..::  :.  *:.****:*:::* ** .*** ***..*:*:

MMAR_1857|M.marinum_M               CMVSPEGACAAYYNFGRLHRDAVKLVGQSGRA
TH_0227|M.thermoresistible__bu      CMVSSEGACAAYYNFGRLHRDAATLVGQAGRG
MSMEG_2702|M.smegmatis_MC2_155      CMVSPEGACAAYYNFGRLHRDTAQLLLRR---
Mflv_3981|M.gilvum_PYR-GCK          TMVSSEGACAAYYLYRRLEVTHA---------
Mvan_2405|M.vanbaalenii_PYR-1       TMVSSEGACAAYYLYRRLEVTNA---------
                                     ***.******** : **.   .