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M. gilvum PYR-GCK Mflv_3981 (-)

VKYLDEFSNPELAHRLIEQIEAVATRRWSIMEVCGGQTHSIIRHGIDQLLPDTVEMIHGPGCPVCVTPLE
IIDKALDIASRPEVIFCSFGDMLRVPGSEKDLFRVKSEGADVRVVYSPLDALTIARDNPDRQVVFFGIGF
ETTAPANAMTVYQAKKLGIENFSLLVSHVLVPPAIAAIMESPTCRVQAFLAAGHVCTVMGTDEYPPLCDK
YGTPIVVTGFEPLDILEGIRRTVIQLEAGRHELENAYPRAVQDTGNPAAKAMLLDVFDVTDRTWRGIGMI
ASSGWRLSPAYRHFDAEHRFAATDLHNEESAICRSGEVLQGLIKPHECTAFGTSCTPRNPLGATMVSSEG
ACAAYYLYRRLEVTHA

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. gilvum PYR-GCK	Mflv_3981	-	-	100% (366)	hydrogenase expression/formation protein HypD

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	-	-	-	-	-
M. marinum M	MMAR_1857	hypD	1e-106	51.63% (368)	hydrogenase-forming protein, HypD
M. avium 104	-	-	-	-	-
M. smegmatis MC2 155	MSMEG_2275	hypD	1e-150	70.44% (362)	hydrogenase expression/formation protein HypD
M. thermoresistible (build 8)	TH_0227	hypD	1e-105	50.95% (367)	hydrogenase expression/formation protein HypD
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	Mvan_2405	-	0.0	89.07% (366)	hydrogenase expression/formation protein HypD

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3981|M.gilvum_PYR-GCK          MKYLDEFSNPELAHRLIEQIEAVATR------RWSIMEVCGGQTHSIIRH
Mvan_2405|M.vanbaalenii_PYR-1       MKYLDEFSNPELAARLIEQITSAATR------RWSIMEVCGGQTHSIIRH
MSMEG_2275|M.smegmatis_MC2_155      MKYLDEFRDPVAARTLVDRINRAATR------TWTMMEVCGGQTHSIIRN
MMAR_1857|M.marinum_M               MKFVDEFRDPAAARKLLTAIEHLAHQPGAGPEHFKFMEVCGGHTHTIYRH
TH_0227|M.thermoresistible__bu      MRFVDEFRDPAAARKLLAAIEVLAAG-GEDGAPFKFMEVCGGHTHTIYRH
                                    *:::*** :*  *  *:  *   *         :.:******:**:* *:

Mflv_3981|M.gilvum_PYR-GCK          GIDQLLPDTVEMIHGPGCPVCVTPLEIIDKALDIASRPEVIFCSFGDMLR
Mvan_2405|M.vanbaalenii_PYR-1       GIDQLLPDTVEMIHGPGCPVCVTPLEIIDKALDIASRPDVVFCSFGDMLR
MSMEG_2275|M.smegmatis_MC2_155      GIDQLLEGSVEFVHGPGCPVCVTPLEVIDRALEIAARDDVIFCSFGDMLR
MMAR_1857|M.marinum_M               GIEHLLPDNVELVHGPGCPVCVIPMGRIDDAMWLAGQPDVIFTCFGDMMR
TH_0227|M.thermoresistible__bu      GIEHLLPPTVELVHGPGCPVCVIPMGRIDDAMWLAAQPDVIFTSFGDMMR
                                    **::**  .**::********* *:  ** *: :*.: :*:* .****:*

Mflv_3981|M.gilvum_PYR-GCK          VPGSEKDLFRVKSEGADVRVVYSPLDALTIARDNPDRQVVFFGIGFETTA
Mvan_2405|M.vanbaalenii_PYR-1       VPGSEKDLFRVKSEGGDVRVVYSPLDALTIAREHPDKQVVFFGIGFETTA
MSMEG_2275|M.smegmatis_MC2_155      VPGSHQDLFSVKARGGDVRIVYSPLDATRVAADNPDKQVVFFGVGFETTA
MMAR_1857|M.marinum_M               VPGSDGSLLDAKARGADVRFVYSPLDALKVAIDNPDKQVVFFAIGFETTA
TH_0227|M.thermoresistible__bu      VPGSNGSLLDAKARGADVRFVYSPLDALKIAVDNPDKRVVYFAIGFETTA
                                    ****. .*: .*:.*.***.*******  :* ::**::**:*.:******

Mflv_3981|M.gilvum_PYR-GCK          PANAMTVYQAKKLGIENFSLLVSHVLVPPAIAAIMESPTCRVQAFLAAGH
Mvan_2405|M.vanbaalenii_PYR-1       PANAMTVYQARRLGIDNFSLLVSHVLVPPAISAIMESPTCRVQAFLAAGH
MSMEG_2275|M.smegmatis_MC2_155      PANAMAVVHAKRLGLKNFSMLVSHVLVPPAMTAILSSPSNRVQGFLAAGH
MMAR_1857|M.marinum_M               PSTAVTLVRARDLELPNFSVFCNHVTIVPPIKAILESPDLRLSGFIGPGH
TH_0227|M.thermoresistible__bu      PSTAVTLLRATELGLRNFSVFCNHVTIVPPIKAILESPDLRLSGFLGPGH
                                    *:.*::: :*  * : ***:: .** : *.: **:.**  *:..*:..**

Mflv_3981|M.gilvum_PYR-GCK          VCTVMGTDEYPPLCDKYGTPIVVTGFEPLDILEGIRRTVIQLEAGRHELE
Mvan_2405|M.vanbaalenii_PYR-1       VCAVMGTDEYPPLCDKYGIPIVVTGFEPLDILEGIRRTVVQLESGRHELE
MSMEG_2275|M.smegmatis_MC2_155      VCSVMGTSEYGPLVEKFDVPIVVTGFEPLDLLEGVRQLVDLLEAGTPELR
MMAR_1857|M.marinum_M               VSTVVGNRPYRFVPEVYHKPLVVAGFEPLDILASVTMLLRQIREGRCEVE
TH_0227|M.thermoresistible__bu      VSTVVGIRPYRFVPEVYRKPLVVAGFEPLDILAAVAMLLRQIREGRCEVE
                                    *.:*:*   *  : : :  *:**:******:* .:   :  :. *  *:.

Mflv_3981|M.gilvum_PYR-GCK          NAYPRAVQDTGNPAAKAMLLDVFDVTDR-TWRGIGMIASSGWRLSPAYRH
Mvan_2405|M.vanbaalenii_PYR-1       NAYPRAVREAGNPAAKAMLLDVFELTDR-AWRGIGVIPGSGWRLSHAYRD
MSMEG_2275|M.smegmatis_MC2_155      NAYSRAVTAEGNVFAQQTLSEVFTVTDR-QWRGIGMIPRSGWTLSPQYAE
MMAR_1857|M.marinum_M               NQYKRVVPEEGNPAALALMGKVFALRPHFEWRGLGFISQSALRLSDDFAE
TH_0227|M.thermoresistible__bu      NQYSRIVAPQGNPAALGMLARVFELRPHFEWRGLGFISQSALKLRDEFAD
                                    * * * *   **  *   :  ** :  :  ***:*.*. *.  *   : .

Mflv_3981|M.gilvum_PYR-GCK          FDAEHRFAATDLHNEESAICRSGEVLQGLIKPHECTAFGTSCTPRNPLGA
Mvan_2405|M.vanbaalenii_PYR-1       YDAEQRFAVSDIHTEESAVCRSGEVLQGLIKPHECAAFGTVCTPRNPLGA
MSMEG_2275|M.smegmatis_MC2_155      FDAELRFGVGHLQVAESAECRSGEVLQGLLKPNECPAFGKTCTPRNPLGA
MMAR_1857|M.marinum_M               FDAELRFAMPGVRVADPKACQCGEVLKGVLKPWECKVFGTACTPETPIGT
TH_0227|M.thermoresistible__bu      YDAERLFDMPGVRVADPKACQCGEVLKGVLRPWECKVFGTACTPETPIGT
                                    :***  *    ::  :.  *:.****:*:::* ** .**. ***..*:*:

Mflv_3981|M.gilvum_PYR-GCK          TMVSSEGACAAYYLYRRLEVTHA---------
Mvan_2405|M.vanbaalenii_PYR-1       TMVSSEGACAAYYLYRRLEVTNA---------
MSMEG_2275|M.smegmatis_MC2_155      TMVSSEGACAAYYQFRRLEAAAHV--------
MMAR_1857|M.marinum_M               CMVSPEGACAAYYNFGRLHRDAVKLVGQSGRA
TH_0227|M.thermoresistible__bu      CMVSSEGACAAYYNFGRLHRDAATLVGQAGRG
                                     ***.******** : **.