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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_0188 | - | - | 100% (216) | serine/threonine-protein kinase PknD |
M. thermoresistible (build 8) | TH_1965 | - | 1e-12 | 36.28% (113) | hypothetical protein MSMEG_6601 |
M. thermoresistible (build 8) | TH_3554 | - | 6e-09 | 33.03% (109) | PUTATIVE - |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3909c | - | 8e-09 | 31.33% (150) | hypothetical protein Mb3909c |
M. gilvum PYR-GCK | Mflv_5210 | - | 1e-34 | 53.79% (132) | protein kinase |
M. tuberculosis H37Rv | Rv3879c | - | 8e-09 | 31.33% (150) | hypothetical protein Rv3879c |
M. leprae Br4923 | MLBr_00020 | - | 5e-08 | 35.37% (82) | hypothetical protein MLBr_00020 |
M. abscessus ATCC 19977 | MAB_4291 | - | 2e-09 | 41.33% (75) | hypothetical protein MAB_4291 |
M. marinum M | MMAR_0618 | - | 8e-13 | 34.51% (113) | hypothetical protein MMAR_0618 |
M. avium 104 | MAV_2158 | - | 2e-41 | 45.89% (207) | serine/threonine protein kinase |
M. smegmatis MC2 155 | MSMEG_4366 | - | 6e-40 | 40.47% (215) | serine/threonine-protein kinase PknD |
M. ulcerans Agy99 | MUL_0583 | - | 8e-12 | 33.33% (111) | hypothetical protein MUL_0583 |
M. vanbaalenii PYR-1 | Mvan_1066 | - | 2e-37 | 55.73% (131) | protein kinase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0618|M.marinum_M -------------------------------------------------- MUL_0583|M.ulcerans_Agy99 -------------------------------------------------- MAB_4291|M.abscessus_ATCC_1997 MANALGLSIGATQLVATPDDPQSQPVVRSSILTLHEDGPPEVGVPSQPGL Mflv_5210|M.gilvum_PYR-GCK -------MS--TPQGGARLGTRFGPYELHSVIGVGGMGEVYRAYDTARER Mvan_1066|M.vanbaalenii_PYR-1 -------MS--TPKGGSRLGTRFGPYELQSVIGVGGMGEVYRAYDTARER MSMEG_4366|M.smegmatis_MC2_155 -------MTPMASNGASRLGTRFGPYELRSLIGVGGMGEVYRAYDTVKGR MAV_2158|M.avium_104 -------MS--SSSRGSRLGTRLGPYELRSLIGTGTLGEVYRAYDTVKDR TH_0188|M.thermoresistible__bu -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 -----MSITRPTGSYARQMLDPGGWVEADEDTFYDRAQEYSQVLQRVTDV Rv3879c|M.tuberculosis_H37Rv -----MSITRPTGSYARQMLDPGGWVEADEDTFYDRAQEYSQVLQRVTDV MLBr_00020|M.leprae_Br4923 -MTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQL MMAR_0618|M.marinum_M -------------------------------------------------- MUL_0583|M.ulcerans_Agy99 -------------------------------------------------- MAB_4291|M.abscessus_ATCC_1997 TLTGFVGRVGDPVGIVAADGSVHRAEWALTEAMRVLIADAVSSANFTAPP Mflv_5210|M.gilvum_PYR-GCK MVAIKLLR------------PEMAADHSFQERFRRESRVAAR-------- Mvan_1066|M.vanbaalenii_PYR-1 MVAIKLLR------------PEMAADHSFQERFRRESRVAAR-------- MSMEG_4366|M.smegmatis_MC2_155 EVAVKLLR------------AEFAADPRFQERFRRESRVAAR-------- MAV_2158|M.avium_104 LVALKLLR------------GELDAG--FRQRLWRECRAVTR-------- TH_0188|M.thermoresistible__bu -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 LDTCRQQKGHVFEGGLWSGGAANAANGALGANINQLMTLQDY-------- Rv3879c|M.tuberculosis_H37Rv LDTCRQQKGHVFEGGLWSGGAANAANGALGANINQLMTLQDY-------- MLBr_00020|M.leprae_Br4923 VIAALAHLD------------DDEPGGDLLGKLETAVRAG---------- MMAR_0618|M.marinum_M -------------------------------------------------- MUL_0583|M.ulcerans_Agy99 -------------------------------------------------- MAB_4291|M.abscessus_ATCC_1997 VLSASIPAHWSPQTVSTLRDAIDRVPAFAPGGRQLKLIPDARAALEALAA Mflv_5210|M.gilvum_PYR-GCK ---LQEPHVIPVHNFGEIDGVLYIDMRLV-EGASLKEVLRSDGPLQPARA Mvan_1066|M.vanbaalenii_PYR-1 ---LQEPHVIPVHDFGEIDGVLYIDMRLV-EGASLKDVLRAEGALPPARA MSMEG_4366|M.smegmatis_MC2_155 ---LQEPHVIPVHDFGDIDGVLYIDMRLV-EGASLKDILRTDGPLDPRRT MAV_2158|M.avium_104 ---LQEPHVLPLHDFGEIDGVPFIDMQLVDDGGSLKELLREQGGLEPSRA TH_0188|M.thermoresistible__bu -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 ---LATVITWHRHIAGLIEQAKSDIGNNVDGAQREIDILENDPSLDADER Rv3879c|M.tuberculosis_H37Rv ---LATVITWHRHIAGLIEQAKSDIGNNVDGAQREIDILENDPSLDADER MLBr_00020|M.leprae_Br4923 ----NLAIAAQVEMEPDFEGMGTTLTAILFAGNRLGLVHIGDSRGYLLRD MMAR_0618|M.marinum_M -------------------------------------------------- MUL_0583|M.ulcerans_Agy99 -------------------------------------------------- MAB_4291|M.abscessus_ATCC_1997 GPGTPDRGVVVVCDLGGSGSSITLADAARGFQQIGQTIRFADFSGQQIDQ Mflv_5210|M.gilvum_PYR-GCK VS-----------IIRQVAAALDDAHA--------NGLVHRDIKP----- Mvan_1066|M.vanbaalenii_PYR-1 VS-----------ILRQVAAALDAAHA--------NGLVHRDIKP----- MSMEG_4366|M.smegmatis_MC2_155 AS-----------IVAQVASALDAAHA--------DGLVHRDIKP----- MAV_2158|M.avium_104 AS-----------ITGQVARALDAAHA--------AGLMHLDVKP----- TH_0188|M.thermoresistible__bu -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 HT-----------AINSLVTATHGANVSLVAETAERVLESKNWKPPKNAL Rv3879c|M.tuberculosis_H37Rv HT-----------AINSLVTATHGANVSLVAETAERVLESKNWKPPKNAL MLBr_00020|M.leprae_Br4923 GE---------------LTQITKDDTFVQTLVDEGRITAEEAHSHPQRSL MMAR_0618|M.marinum_M -------------------------------------------------- MUL_0583|M.ulcerans_Agy99 -------------------------------------------------- MAB_4291|M.abscessus_ATCC_1997 MLLTQVLTDLNQDPEGTTSVGALTRLRDQCRLAKERLSGDTATSVPVQLP Mflv_5210|M.gilvum_PYR-GCK ENVLLTGDDFAYLVDFGIAHGGGEASVTSTGLVVGSSAYMAPERFSGERG Mvan_1066|M.vanbaalenii_PYR-1 ENVLLTPDDFAYLVDFGIAHGGGEASVTSTGLVVGSSAYMAPERFSGERG MSMEG_4366|M.smegmatis_MC2_155 ENVLLTGDDFAYLVDFGIAHVGGEASVTMTGMLIGSSAYMAPERFSGETV MAV_2158|M.avium_104 ENILLTHDHFTYLADFGLAQAAGDEKLSRT--------YMAPERFTTGSL TH_0188|M.thermoresistible__bu --VVVA----AVIVLFGVAAG----------------------------- Mb3909c|M.bovis_AF2122/97 EDLLQQKSPPPPDVPTLVVPSPGTPGTPGTPGTPITPGTPITPGTPITPG Rv3879c|M.tuberculosis_H37Rv EDLLQQKSPPPPDVPTLVVPSPGTPGTPGTP---------------ITPG MLBr_00020|M.leprae_Br4923 IMRALTGHEVDPTLTMREARAGDRYLLCSDG-----LSDPVSDETILEAL MMAR_0618|M.marinum_M -------------------------------------------------- MUL_0583|M.ulcerans_Agy99 -------------------------------------------------- MAB_4291|M.abscessus_ATCC_1997 GITTDVRLTRAELEGHLRGPLSNLINAIQDTVERNGIHPANITAVASVGG Mflv_5210|M.gilvum_PYR-GCK GPASDIYSLACLLYESLTGRAPFEAADVRQVWSAHMFAAPPRPSIMRRGV Mvan_1066|M.vanbaalenii_PYR-1 GPASDVYSLACLLYESLTGRAPFEAADVRQVWSAHMFAPPPRPSIMRRGV MSMEG_4366|M.smegmatis_MC2_155 GPPADIYALACLVYESLIGRPPYEAGDLRQLMSAHMFSAPPRPSIMRRGV MAV_2158|M.avium_104 GPQTDIYSLACVLYECLTGQPPFEGADPGELRSAHLLSPAPRPSIMRRGV TH_0188|M.thermoresistible__bu --------LAAVLVSDRDGPAP-----------SSQLAVPPAQTTEPTGT Mb3909c|M.bovis_AF2122/97 TPITPGTPITPIPGAPVTPITPTPGTPVTPVTPGKPVTPVTPVKPGTPGE Rv3879c|M.tuberculosis_H37Rv TPITPGTPITPIPGAPVTPITPTPGTPVTPVTPGKPVTPVTPVKPGTPGE MLBr_00020|M.leprae_Br4923 QIPDVAESAYRLIELALRGGGPDNVTVVVADVIDYDYGQTQPILAGAVSG MMAR_0618|M.marinum_M ----------------------------------------------MARH MUL_0583|M.ulcerans_Agy99 ----------------------------------------------MARH MAB_4291|M.abscessus_ATCC_1997 GASIPLVTQQLSERMRVPVITAPQPQLAAARGVALLATRPDLPPQDATAM Mflv_5210|M.gilvum_PYR-GCK SRAFDDVIARGMAKNPTERYATAGELARAAAAAAS----------AAPVA Mvan_1066|M.vanbaalenii_PYR-1 SRTFDDVVARGMAKQPHDRYPTAGELARAASAAAE----------GAPAA MSMEG_4366|M.smegmatis_MC2_155 PRAFDEVIATAMAKDPAARYATAGELARAVSAAAAG---------EAPPS MAV_2158|M.avium_104 GRAFDDIITRGMAKQRSARFASAGELARAASEAVFA--------AYEPVS TH_0188|M.thermoresistible__bu T--------------------------------------------AAPTT Mb3909c|M.bovis_AF2122/97 PTPITPVTPPVAPATPATPATPVTPAPAPHPQPAPAP-------APSPGP Rv3879c|M.tuberculosis_H37Rv PTPITPVTPPVAPATPATPATPVTPAPAPHPQPAPAP-------APSPGP MLBr_00020|M.leprae_Br4923 EESQQMALPNTAASRASAIVPRKEIAKSMAPQVDKVHQQRWSQRQTGITL MMAR_0618|M.marinum_M DPPDYGAGDPTAYGNYGYGD------------------------------ MUL_0583|M.ulcerans_Agy99 DPPDYGAGDPTAYGNYGYGD------------------------------ MAB_4291|M.abscessus_ATCC_1997 RPVEQPPGDATMMRPVPTGTGTFAAPVAAAANEEPELAWSQDDSAPDLAP Mflv_5210|M.gilvum_PYR-GCK EPVPPVTP----PSTRQFSGVHP---------------------AMTP-P Mvan_1066|M.vanbaalenii_PYR-1 ETVAPVTP----PSTRQFSTVYP---------------------TPPPMP MSMEG_4366|M.smegmatis_MC2_155 KPTPPQVPGRPPTPTRQFSELYPNPEHTGFTPYPPAYPSVPAPPRRTPTP MAV_2158|M.avium_104 AAAGLGGPRPLPAPPAQFDDPDD-----------------------TLGP TH_0188|M.thermoresistible__bu GPTRSSTP---TTPTTRTTPTT------------------------TTSP Mb3909c|M.bovis_AF2122/97 QPVTPATPGPSGPATPGTPGGEPAPHVKPAALAEQPGVPGQHAGGGTQSG Rv3879c|M.tuberculosis_H37Rv QPVTPATPGPSGPATPGTPGGEPAPHVKPAALAEQPGVPGQHAGGGTQSG MLBr_00020|M.leprae_Br4923 TLLVLLVLAGVAIGRWVIRDNYYIAEYSG------------------KVS MMAR_0618|M.marinum_M -QGGGYGQ----------QPPPEPTPGWRKPLALAG-------------- MUL_0583|M.ulcerans_Agy99 -QRGGYGQ----------QPPPEPTPGWRKPLALAG-------------- MAB_4291|M.abscessus_ATCC_1997 LQETGYQSGYTVDLDDEYQGPTEATTARPELRFSHGPYADEDDYDDYPPL Mflv_5210|M.gilvum_PYR-GCK PAPAPIAA-------ARRPGRGQGALVAGIVVMFVAAAVLA--------- Mvan_1066|M.vanbaalenii_PYR-1 PMPAVAPP-------ARRFSRGQVGLVAATVVMFTAALVLA--------- MSMEG_4366|M.smegmatis_MC2_155 PAPAAVAAPAVRTPGKKRFTRTQMMLVVATVVLFGIAAVLA--------- MAV_2158|M.avium_104 PPVGERPP-------RGPAGRLPVVVTAVAVLMLIAGVVLS--------- TH_0188|M.thermoresistible__bu ERTSPVPS------------------------------------------ Mb3909c|M.bovis_AF2122/97 PAHADESAASVTPAAASGVPGARAAAAAPSGTAVGAGARSS--------- Rv3879c|M.tuberculosis_H37Rv PAHADESAASVTPAAASGVPGARAAAAAPSGTAVGAGARSS--------- MLBr_00020|M.leprae_Br4923 IVRGIQGSLLGMPLHEPYLVGCLNTRNELSLISYGQSGGHLN-------- MMAR_0618|M.marinum_M --------WGVLIAVLIGLIIFGIIQLAHGRPTPASVTKTVTATMTTTTP MUL_0583|M.ulcerans_Agy99 --------WGVLIAVLIGLIIFGIIQLAHGRPTPASVTKTVTATMTTTTP MAB_4291|M.abscessus_ATCC_1997 PWYRRPLVWFIAAAAVAGIAFTGMMVSLTSSESPAPATTTPSVNVVPSTG Mflv_5210|M.gilvum_PYR-GCK --LVLVFTGGSDPQP-PRIAAP----PSSSSDTSTPPSTSAVEGVSGTDS Mvan_1066|M.vanbaalenii_PYR-1 --AVLVFSGGDTGSPSPRIAAP----PSSSSEAPSTSSASAVEGVSGTDS MSMEG_4366|M.smegmatis_MC2_155 --TMLVGGDDNASTGNTGITPPEGATSTSESTTTTTSNRSATANVSGTDE MAV_2158|M.avium_104 --VKTVVGTHHNNSAPPPAPTTRALAPPPPTTPPPPLTPTLSRPVTGADG TH_0188|M.thermoresistible__bu -----------ASPATPPATPP-------TSPTSPVASPVTPAAVPGADR Mb3909c|M.bovis_AF2122/97 --VGTAAASGAGSHAATGRAPVATSDKAAAPSTRAASARTAPPARPPSTD Rv3879c|M.tuberculosis_H37Rv --VGTAAASGAGSHAATGRAPVATSDKAAAPSTRAASARTAPPARPPSTD MLBr_00020|M.leprae_Br4923 ----------CQVMTLRDLRPSGGAQVQAGLPGGNLDQAESQLRKLLADS : MMAR_0618|M.marinum_M TTTTTAPTKTTTTTTTTTTTTTTTTTT-------------TTTTTTTTTT MUL_0583|M.ulcerans_Agy99 -TTTTAPTKTTTTTTTTTTTTTTTTTT-------------TTTTT----- MAB_4291|M.abscessus_ATCC_1997 DAPAEPPPSPEPPPPPQTHTVTQSVQPPPPSPEPPPPPPPTTTTTTTPPT Mflv_5210|M.gilvum_PYR-GCK QGFVGHTARCDSGDTPAALIRTSLS---------LAIICDRGDGDYYYRG Mvan_1066|M.vanbaalenii_PYR-1 QGFVGHTARCDSGSTPAALIRTSLS---------LAIICETSDGDYYYRG MSMEG_4366|M.smegmatis_MC2_155 QGFVGHTARCDSDATPAALIRTATS---------LAIICERDSGGYYYRG MAV_2158|M.avium_104 LGFIGETARCDPGNPPAAVVRTAKS---------LAVVCQNLSGSYYYRG TH_0188|M.thermoresistible__bu QGFIGHAARCDSGSTPAAMVRTDNS---------LAVVCETRSGDYYYRG Mb3909c|M.bovis_AF2122/97 HIDKPDRSESADDGTPVSMIPVSAARAARDAATAAASARQRGRGDALRLA Rv3879c|M.tuberculosis_H37Rv HIDKPDRSESADDGTPVSMIPVSAARAARDAATAAASARQRGRGDALRLA MLBr_00020|M.leprae_Br4923 LLPTCPPPRATSPPGPFTMPTDSGT----------------PQPTNTASP . . : MMAR_0618|M.marinum_M TTTTTPTTTTTTTTAPTTTTTTTTNPMSPGAMPTFPSQLTPSIP------ MUL_0583|M.ulcerans_Agy99 -TTTTPTTTTTTTTAPTTTTTTTTNPMSPGAMPTFPSQLTPSIP------ MAB_4291|M.abscessus_ATCC_1997 TTTTTTTTTTTTTTTTTTPTTTTTQPTTTTTQPTSTSRPAITIP------ Mflv_5210|M.gilvum_PYR-GCK ERLRDGANREIDGARRSGDGFTVTG-SDGARYDVQPDQLTISSG------ Mvan_1066|M.vanbaalenii_PYR-1 ERLRDGANREIQGAQRSGDGFVVTG-SDGARYDVQPDQLTISSN------ MSMEG_4366|M.smegmatis_MC2_155 ERLRDGANLKIDDAQRSGDGYVAVNPADGARYEVSPEGLTIMSN------ MAV_2158|M.avium_104 ERIRDGAHIELSNAERVEDGFDVTNPVDGVVYEVRPNRLRIISF------ TH_0188|M.thermoresistible__bu ERLSDGASIELRNARPAGDGFDAVNPADGTRYEVRPDRLTIISN------ Mb3909c|M.bovis_AF2122/97 RRIAAALNASDNNAGDYGFFWITAVTTDGSIVVANSYGLAYIPDGMELPN Rv3879c|M.tuberculosis_H37Rv RRIAAALNASDNNAGDYGFFWITAVTTDGSIVVANSYGLAYIPDGMELPN MLBr_00020|M.leprae_Br4923 TSTTPPTITSSSGTAPTNISPTSSPASTAPTTPVGTSQTVTILP------ : . . MMAR_0618|M.marinum_M ---------TVINLPPGL-------------------------------- MUL_0583|M.ulcerans_Agy99 ---------TVINLPPGL-------------------------------- MAB_4291|M.abscessus_ATCC_1997 ---------GLPPIPIGPRN------------------------------ Mflv_5210|M.gilvum_PYR-GCK ----GSVDSAEPALEYGSAQ------------------------------ Mvan_1066|M.vanbaalenii_PYR-1 ----GSVDSAEPALEYGSAQ------------------------------ MSMEG_4366|M.smegmatis_MC2_155 ----GHVDSSEPPEEYGSK------------------------------- MAV_2158|M.avium_104 ----GHVDSSEPVLQYATAS------------------------------ TH_0188|M.thermoresistible__bu ----GRIDANEPVQQYAGR------------------------------- Mb3909c|M.bovis_AF2122/97 KVYLASADHAIPVDEIARCATYPVLAVQAWAAFHDMTLRAVIGTAEQLAS Rv3879c|M.tuberculosis_H37Rv KVYLASADHAIPVDEIARCATYPVLAVQAWAAFHDMTLRAVIGTAEQLAS MLBr_00020|M.leprae_Br4923 ------PPPPQPGIDCRAVA------------------------------ MMAR_0618|M.marinum_M -------------------------------------------------- MUL_0583|M.ulcerans_Agy99 -------------------------------------------------- MAB_4291|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_5210|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1066|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_4366|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2158|M.avium_104 -------------------------------------------------- TH_0188|M.thermoresistible__bu -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 SDPGVAKIVLEPDDIPESGKMTGRSRLEVVDPSAAAQLADTTDQRLLDLL Rv3879c|M.tuberculosis_H37Rv SDPGVAKIVLEPDDIPESGKMTGRSRLEVVDPSAAAQLADTTDQRLLDLL MLBr_00020|M.leprae_Br4923 -------------------------------------------------- MMAR_0618|M.marinum_M -------------------------------------------------- MUL_0583|M.ulcerans_Agy99 -------------------------------------------------- MAB_4291|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_5210|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1066|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_4366|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2158|M.avium_104 -------------------------------------------------- TH_0188|M.thermoresistible__bu -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 PPAPVDVNPPGDERHMLWFELMKPMTSTATGREAAHLRAFRAYAAHSQEI Rv3879c|M.tuberculosis_H37Rv PPAPVDVNPPGDERHMLWFELMKPMTSTATGREAAHLRAFRAYAAHSQEI MLBr_00020|M.leprae_Br4923 -------------------------------------------------- MMAR_0618|M.marinum_M --------------------------------------- MUL_0583|M.ulcerans_Agy99 --------------------------------------- MAB_4291|M.abscessus_ATCC_1997 --------------------------------------- Mflv_5210|M.gilvum_PYR-GCK --------------------------------------- Mvan_1066|M.vanbaalenii_PYR-1 --------------------------------------- MSMEG_4366|M.smegmatis_MC2_155 --------------------------------------- MAV_2158|M.avium_104 --------------------------------------- TH_0188|M.thermoresistible__bu --------------------------------------- Mb3909c|M.bovis_AF2122/97 ALHQAHTATDAAVQRVAVADWLYWQYVTGLLDRALAAAS Rv3879c|M.tuberculosis_H37Rv ALHQAHTATDAAVQRVAVADWLYWQYVTGLLDRALAAAC MLBr_00020|M.leprae_Br4923 ---------------------------------------