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M. thermoresistible (build 8) TH_0153 (-)

annotation: virulence factor Mce family protein
coordinates: 327828 - 329042
length: 405

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0153 - - 100% (405) virulence factor Mce family protein
M. thermoresistible (build 8) TH_0154 - e-144 61.52% (395) virulence factor Mce family protein
M. thermoresistible (build 8) TH_2690 - 6e-63 38.27% (358) PUTATIVE virulence factor Mce family protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0604 mce2A 1e-142 62.97% (397) MCE-family protein MCE2A
M. gilvum PYR-GCK Mflv_0711 - 1e-136 57.29% (398) virulence factor Mce family protein
M. tuberculosis H37Rv Rv0589 mce2A 1e-143 62.97% (397) MCE-family protein MCE2A
M. leprae Br4923 MLBr_02589 mce1A 1e-132 53.36% (431) putative cell invasion protein
M. abscessus ATCC 19977 MAB_4153c - 5e-56 34.95% (392) MCE-family protein
M. marinum M MMAR_4883 mce2A 1e-137 59.00% (400) MCE-family protein Mce2A
M. avium 104 MAV_4551 - 1e-144 63.80% (395) virulence factor Mce family protein
M. smegmatis MC2 155 MSMEG_0134 - 1e-144 61.52% (395) virulence factor Mce family protein
M. ulcerans Agy99 MUL_0415 mce2A 1e-133 58.00% (400) MCE-family protein Mce2A
M. vanbaalenii PYR-1 Mvan_0134 - 1e-141 60.55% (398) virulence factor Mce family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0604|M.bovis_AF2122/97            MPTLVT-----RKNRRAWLYVEGVVLLLVGALVLVLVYKQFRGEFTPKTE
Rv0589|M.tuberculosis_H37Rv         MPTLVT-----RKNRRAWLYVEGVVLLLVGALVLVLVYKQFRGEFTPKTE
MAV_4551|M.avium_104                MATPVP-----QRGRRAWVYVEGVLLLLVCALVLALVYLQFRGDFTPKTK
TH_0153|M.thermoresistible__bu      LTILQE-----DQRRRPRYKMLGALLLILLAAAVALVWGQFRGAFTPVTP
Mflv_0711|M.gilvum_PYR-GCK          MTAP------MNTKRQPPYKIAGVVLALVTILILVLVYLQFRGDFLPRTQ
Mvan_0134|M.vanbaalenii_PYR-1       MTVPQA---ALNTRRQPPYKLAGLVLAILTVIAVTLVYLQFRGDFMARTQ
MSMEG_0134|M.smegmatis_MC2_155      MTEPPAPTAPLNKPKTPPYKLAGLILGLVGVLVLALTWMQFRGQFEDKVQ
MMAR_4883|M.marinum_M               ----------MDPRSRPPYKIIGLAALMVLVFFGAMLYWQFRGTFIPKTR
MUL_0415|M.ulcerans_Agy99           ----------MDPRSRPPCKIIGLAALMVLVFFGAMLYWQFRGTFIPKTR
MLBr_02589|M.leprae_Br4923          MTSSTK----INASRKPPYKLAGVGLLVVAVVIFGLVYGQFRGNFTPKSK
MAB_4153c|M.abscessus_ATCC_199      ---------MSDTSTRRAVRLAGTVLASVLVLLTVLTYLAYNDAFADTKP
                                                        : *     :      : :  :.. *     

Mb0604|M.bovis_AF2122/97            LTMVASRAGLVMEAGSKVTYNGVEIGRVGSISEIERDGRPAAKLVLDVNP
Rv0589|M.tuberculosis_H37Rv         LTMVAFRAGLVMEAGSKVTYNGVEIGRVGSISEIERDGRPAAKLVLDVNP
MAV_4551|M.avium_104                LTMVATRAGLVMETGSKVTYNGVAIGRVADISEIERDGAPAAKLVLDVDP
TH_0153|M.thermoresistible__bu      LTMLAARAGLVMEPGAKVTYNGVQIGRVAEIAAVDGNGDTLAEFRLDVEP
Mflv_0711|M.gilvum_PYR-GCK          LTMISARSGLSLDSGSKVTFNGVEIGKVSEVEETTVGGEPRAKILLEVNP
Mvan_0134|M.vanbaalenii_PYR-1       LTMISARSGLSMDPGAKVTYNGVEIGRVGNVEETSVDGEPRAKIILDVNP
MSMEG_0134|M.smegmatis_MC2_155      LTVLSGRAGLSMDPGSKVTFNGVPIGRLASIDVVEVDDNPEARLTLDVDP
MMAR_4883|M.marinum_M               LTMIAPRAGLVTDPGAKVTFNGVQIGRVSSITEVTHDGAPAARFALDVTP
MUL_0415|M.ulcerans_Agy99           LTMIAPRAGLVTDPGAKVTFNGVQIGRVSSITEVTHDGAPAARFALDVTP
MLBr_02589|M.leprae_Br4923          LTMLADRAGLVMDRGSKITYNGVKIGRVADISETVRNGRPVAEFTLDVYP
MAB_4153c|M.abscessus_ATCC_199      ITVVSPRAGLVMEEGGKVKFHGLQIGKVTSISYAN----DQAKLELAVNA
                                    :*::: *:**  : *.*:.::*: **:: .:          *.: * * .

Mb0604|M.bovis_AF2122/97            RYISLIPVNVVADIEAATLFGNKYVALSAPKIPQQQRISSHDVIDVGSVT
Rv0589|M.tuberculosis_H37Rv         RYISLIPVNVVADIEAATLFGNKYVALSAPKIPQQQRISSHDVIDVGSVT
MAV_4551|M.avium_104                RYVNLIPANVVATIEAATLFGNKYVSLSAPENPSRQRISPRDVIDARSVT
TH_0153|M.thermoresistible__bu      RFVELIPANVHAEIKATTVFGNKYVALTAPPQPAAARISPDRPIDATAVT
Mflv_0711|M.gilvum_PYR-GCK          KYLKLIPRNVNADISATTVFGNKYVSFTSPENPQSERISASDVIDVTSVT
Mvan_0134|M.vanbaalenii_PYR-1       KYLDLIPSNVNADISATTVFGNKYVSFTTPEDPRPERISASDVIDVTSVT
MSMEG_0134|M.smegmatis_MC2_155      KYLDLIPENANVELRATTVFGNKYISFLSPKNPSAERLSASTPIRAQGVT
MMAR_4883|M.marinum_M               KYIGSIPANVSATIKATTVFGNKYVSLTSPTDPAPQHITPASVIYATSVT
MUL_0415|M.ulcerans_Agy99           KYIGSIPANVSATIKATTVFGNKYVSLTSPTDPAPQHITPASVIYATSVT
MLBr_02589|M.leprae_Br4923          RYLSLIPANVNADIKATTVFGGKYVSLTTPEHPSQKRLTPQTVIDARSVT
MAB_4153c|M.abscessus_ATCC_199      KDLRLIPSNATVRIAGTTVFGAKSVEFLAPQKPSDSSLRPGATVTAEAVA
                                    : :  ** *. . : .:*:** * : : :*  *    : .   : . .*:

Mb0604|M.bovis_AF2122/97            TEFNTLFETITSIAEKVDPIELNATLSAVAQAPDGLGGKFGESIVNGNQI
Rv0589|M.tuberculosis_H37Rv         TEFNTLFETITSIAEKVDPIELNATLSAVAQALDGLGGKFGESIVNGNQI
MAV_4551|M.avium_104                TEFNTLFETVTSIAEKVSPIELNATLSALAQALDGLGGKFGESIVNGNQI
TH_0153|M.thermoresistible__bu      TEFNTLFETITSLSEKIDPVKLNATLTALADAFDGLGADFGRSLVDGNAI
Mflv_0711|M.gilvum_PYR-GCK          TEFNTLFETVVEIAEQVDPIKLNQTLTATAQALDGLGDRFGESIINGNQI
Mvan_0134|M.vanbaalenii_PYR-1       TEFNTLFETVVSLADQVDPIKLNQTLTATAQALDGLGDRFGESIINGNQI
MSMEG_0134|M.smegmatis_MC2_155      TEFNTLFETITAISEQVDPIKLNETLTAAAQALDGLGDKFGRSIVDGNAI
MMAR_4883|M.marinum_M               TEFNTLFENVTAISEKVDPVKLNLTLSAAAQALSGLGDRLGTALVNGNAI
MUL_0415|M.ulcerans_Agy99           TEFNTLFENVTAISEKVDPDKLNLTLNAAAQALSGLGDRLGTALVNGNAI
MLBr_02589|M.leprae_Br4923          TEINTLFQTITLIAEKVDPIKLNLTLSAAAQSLAGLGERFGQSIVNGNSV
MAB_4153c|M.abscessus_ATCC_199      LEVNTVFENLTRLLGKIDPVNLNATLTAVGEGLRGNGDNFGQGLVELDQY
                                     *.**:*:.:. :  ::.* :** **.* .:.  * *  :* .::: :  

Mb0604|M.bovis_AF2122/97            LAQLNPRLPQLGYDVRRLADLGEVYVDASPDLWSFLQNALTTARTLTSQQ
Rv0589|M.tuberculosis_H37Rv         LAQLNPRLPQLGYDVRRLADLGEVYVDASPDLWSFLQNALTTARTLTSQQ
MAV_4551|M.avium_104                LAQLNPRMPQIRYDVRRLADLAVAYTKAAPDLLDFLSNAVTTARTLTRQQ
TH_0153|M.thermoresistible__bu      LADLNARMPQIRHDVVALADLADIYVAASPNLWSFLDDAATTAQTVFRQR
Mflv_0711|M.gilvum_PYR-GCK          LAEINPQMPQIRRDNQLLADFGEVYSNAAPDLFDGLQNAVTTARTLNEQQ
Mvan_0134|M.vanbaalenii_PYR-1       LSEINPQMPQIRRDNQLLADLGDVYADAAPDLFDGLQNAVTTARTLNEQQ
MSMEG_0134|M.smegmatis_MC2_155      LADVNPRMPQIRRDITGLANLGEVYADASPDLFDGLDNAVTTARTLNEQR
MMAR_4883|M.marinum_M               LDDVNPLMPQVHRDITGLAALGDIYADASTDLWDAVNSTVTVARTVNQRR
MUL_0415|M.ulcerans_Agy99           LDDVNPLMPQVHRDIRGLAALGDIYADASADLWDAVNSTVTVARTVNQRR
MLBr_02589|M.leprae_Br4923          LDDVNSQLPQARHDIQQLASLGDTYANSASDFFDFLNNSIVTSRTINQQQ
MAB_4153c|M.abscessus_ATCC_199      LDQLNPKLPALQQDFRQAGQVGQIYGDAAPDIVRILDNLPALSRTVVDQQ
                                    * ::*. :*    *    . ..  *  ::.::   :..  . ::*:  ::

Mb0604|M.bovis_AF2122/97            RDLDAALLAATGAGNTGEDVFARGGPYLARAAADLVPTATLLDTYSPELF
Rv0589|M.tuberculosis_H37Rv         RDLDAALLAATGAGNTGEDVFARGGPYLARAAADLVPTATLLDTYSPELF
MAV_4551|M.avium_104                GDLDAALLAAVGVGHEGEDIFARGGPYLARGAADLVPTAELLDTYSPELF
TH_0153|M.thermoresistible__bu      DDLDNALTAAIGFGDTGADVFERGAPYLIRGAADLTVSARLLDRHSPALF
Mflv_0711|M.gilvum_PYR-GCK          GDVDQALMAAVGFGNTGGDIFERGGPYLVRGARDLVPTSALLDKYSPSFF
Mvan_0134|M.vanbaalenii_PYR-1       GDVDQALMAAVGFGNTGGDVFERGGPYLARGAEDLVPTTALLDKYSPSFF
MSMEG_0134|M.smegmatis_MC2_155      GNLDQALVAAVGFGNTGGDIFERGGPYLVRGAQDLLPTSALLDEYSPALF
MMAR_4883|M.marinum_M               SDLDAALLASVGLANNGSEVFERGGPYLTRGAADLVPTGQLLDEYSPEIF
MUL_0415|M.ulcerans_Agy99           SDLDAALLASVGLANNGSEVFERGGPYLTRGAADLVPTGQLLDEYSPEIF
MLBr_02589|M.leprae_Br4923          KDLDQVLLAAVGFGNTGADIFSRSGPYLARGAADLVPTAQLLDTYSPAIF
MAB_4153c|M.abscessus_ATCC_199      QDLKATLLAAIGLGNNGYETLAPAEKDLTAALQRLRAPATLLGRYSPEIP
                                     ::. .* *: * .. * : :  .   *  .   *  .  **. :** : 

Mb0604|M.bovis_AF2122/97            CMIRNFHDAAPKVADAVGGNGYSLA-------------------------
Rv0589|M.tuberculosis_H37Rv         CMIRNFHDAAPKVADAVGGNGYSLA-------------------------
MAV_4551|M.avium_104                CMIRNFHDAAPEVAKAAGGNGYSLA-------------------------
TH_0153|M.thermoresistible__bu      CGVRNIARAAPAVRSALGDNGYSLA-------------------------
Mflv_0711|M.gilvum_PYR-GCK          CMMRNYHDVEPKIADALGGNGYSLK-------------------------
Mvan_0134|M.vanbaalenii_PYR-1       CMIRNYHDVEPKIADALGGNGYSLK-------------------------
MSMEG_0134|M.smegmatis_MC2_155      CTIRNYHDAAPKLAGALGGNGYSLL-------------------------
MMAR_4883|M.marinum_M               CTIRNYDEVAPRIRNALGFNGYSLG-------------------------
MUL_0415|M.ulcerans_Agy99           RTIRNYDEVAPRIRNALGFNGYSLG-------------------------
MLBr_02589|M.leprae_Br4923          CTLRNYHDIEPKVTSFLGGNGYSINDHVELLSGLGFLLNPTSAISIIGAG
MAB_4153c|M.abscessus_ATCC_199      CTLQAISKALVTFTPLIGGVRPGLF-------------------------
                                      ::        .    *    .:                          

Mb0604|M.bovis_AF2122/97            -----------AAGTILGAP--NPYVYPDNLPRVNAHGGPGGR--PGCWQ
Rv0589|M.tuberculosis_H37Rv         -----------AAGTILGAP--NPYVYPDNLPRVNAHGGPGGR--PGCWQ
MAV_4551|M.avium_104                -----------AAGSIVGAP--NPYVYPDNLPRVNAHGGPGGR--PGCWQ
TH_0153|M.thermoresistible__bu      -----------TNSSLLGAE--NRYLYPDNLPRVNAKGGPGGR--PGCWQ
Mflv_0711|M.gilvum_PYR-GCK          -----------THSQVLGLGAGNAYVYPDNLPRVNAKGGPGGR--PGCWQ
Mvan_0134|M.vanbaalenii_PYR-1       -----------THSEVLGLGAGNAYVYPDNLPRVNAKGGPGGR--PGCWQ
MSMEG_0134|M.smegmatis_MC2_155      -----------TNSLVVGVG--NPYVYPDNLPRVNAKGGPEGR--PGCWQ
MMAR_4883|M.marinum_M               ---------AASSGAISGAP--NPYIYPENLPRVNARGGPGGR--PGCWQ
MUL_0415|M.ulcerans_Agy99           ---------AAPSGAISGAP--NPYIYPENLPRVNARGGPGGR--PGCWQ
MLBr_02589|M.leprae_Br4923          VLSQGLLAPLGLAGVVNGAA--NPYIYPENLPRVNARGGPGGA--PGCWQ
MAB_4153c|M.abscessus_ATCC_199      ----------LTNSFPLGAP---VYTYPDSLPIVNASGGPNCRGLPNIPT
                                                 .   *      * **:.** *** ***     *.   

Mb0604|M.bovis_AF2122/97            TITRELWP-APYLVMDTG-ASLAPYNHVELGQPMFTEYVWGRQYGENTIN
Rv0589|M.tuberculosis_H37Rv         TITRELWP-APYLVMDTG-ASLAPYNHVELGQPMFTEYVWGRQYGENTIN
MAV_4551|M.avium_104                KITRDLWP-APYLVMDTG-ASLAPYNHLEIGQPLATEFVWGRQYGENTIN
TH_0153|M.thermoresistible__bu      EITRELWP-APWLVMDTG-ASIAPYNHFELGRPIVAEYVWGRQGGEDTIN
Mflv_0711|M.gilvum_PYR-GCK          PITRDLWP-APFLVLDTG-ASVAPYNHMELGQPLFTEYVWGRQVGEHTIN
Mvan_0134|M.vanbaalenii_PYR-1       PITRDLWP-APFLVLDTG-ASIAPYNHMELGQPLLTEYVWGRQVGEHTIN
MSMEG_0134|M.smegmatis_MC2_155      PITRDLWP-FPYLVMDTG-ASIAPYNHFELGQPMFAEYVWGRQVGENTIN
MMAR_4883|M.marinum_M               TITRDLWP-APYLVMDVG-ANMAPYNHLEIGQPLLNEYVWGRQFGENTIN
MUL_0415|M.ulcerans_Agy99           TITRDLWP-APYLVMNVG-ANMAPYNHLEIGQPLLNEYVWGRQFGENTIN
MLBr_02589|M.leprae_Br4923          HITRDLWP-TPELVMDTG-NSIAPYNHLDSGSPYAIEYVWGRQVGDNTIN
MAB_4153c|M.abscessus_ATCC_199      KMQNGSWFRSPFLVTDNAYIPYKPLEELQVNAPDTLQYLYNGAFAKRSEF
                                     : .  *   * ** : .     * :..: . *   ::::.   .. :  

Mb0604|M.bovis_AF2122/97            P
Rv0589|M.tuberculosis_H37Rv         P
MAV_4551|M.avium_104                P
TH_0153|M.thermoresistible__bu      P
Mflv_0711|M.gilvum_PYR-GCK          P
Mvan_0134|M.vanbaalenii_PYR-1       P
MSMEG_0134|M.smegmatis_MC2_155      P
MMAR_4883|M.marinum_M               P
MUL_0415|M.ulcerans_Agy99           P
MLBr_02589|M.leprae_Br4923          P
MAB_4153c|M.abscessus_ATCC_199      -

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0153	-	-	100% (405)	virulence factor Mce family protein
M. thermoresistible (build 8)	TH_0154	-	e-144	61.52% (395)	virulence factor Mce family protein
M. thermoresistible (build 8)	TH_2690	-	6e-63	38.27% (358)	PUTATIVE virulence factor Mce family protein