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M. tuberculosis H37Rv Rv3870 (-)

annotation: POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN
coordinates: 4346481 - 4348724
length: 747

MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAMLGMIAIMVAGGTRQLSPYML
MMPLMMIVMMVGGLAGSTGGGGKKVPEINADRKEYLRYLAGLRTRVTSSATSQVAFFSYHAPHPEDLLSI
VGTQRQWSRPANADFYAATRIGIGDQPAVDRLLKPAVGGELAAASAAPQPFLEPVSHMWVVKFLRTHGLI
HDCPKLLQLRTFPTIAIGGDLAGAAGLMTAMICHLAVFHPPDLLQIRVLTEEPDDPDWSWLKWLPHVQHQ
TETDAAGSTRLIFTRQEGLSDLAARGPHAPDSLPGGPYVVVVDLTGGKAGFPPDGRAGVTVITLGNHRGS
AYRIRVHEDGTADDRLPNQSFRQVTSVTDRMSPQQASRIARKLAGWSITGTILDKTSRVQKKVATDWHQL
VGAQSVEEITPSRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGAGPHGMLIGTTGSGKSEFLR
TLILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAAVVTNMAEEAELVSRMGEVLTGELDRRQSILR
QAGMKVGAAGALSGVAEYEKYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHLL
LATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNKESGVGFLRVGMEDPVKFSTFY
ISGPYMPPAAGVETNGEAGGPGQQTTRQAARIHRFTAAPVLEEAPTP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3870--100% (747)POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN
M. tuberculosis H37RvRv3447c-e-11637.74% (742) hypothetical protein Rv3447c
M. tuberculosis H37RvRv0284-1e-9432.92% (720) hypothetical protein Rv0284

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3900-0.0100.00% (747) hypothetical protein Mb3900
M. gilvum PYR-GCKMflv_0771-0.080.32% (747) cell divisionFtsK/SpoIIIE
M. leprae Br4923MLBr_00053-0.085.39% (746) hypothetical protein MLBr_00053
M. abscessus ATCC 19977MAB_3756c-1e-13539.34% (755) putative FtsK/SpoIIIE family protein
M. marinum MMMAR_5445-0.089.56% (747) hypothetical protein MMAR_5445
M. avium 104MAV_4390-1e-10636.54% (739) ftsk/SpoIIIE family protein
M. smegmatis MC2 155MSMEG_0061-0.080.91% (744) ftsk/SpoIIIE family protein
M. thermoresistible (build 8)TH_4195-0.083.02% (742) PUTATIVE cell divisionFtsK/SpoIIIE
M. ulcerans Agy99MUL_0860-1e-10636.66% (731) hypothetical protein MUL_0860
M. vanbaalenii PYR-1Mvan_0074-0.079.78% (742) cell divisionFtsK/SpoIIIE

CLUSTAL 2.0.9 multiple sequence alignment


Rv3870|M.tuberculosis_H37Rv         MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAM
Mb3900|M.bovis_AF2122/97            MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAM
MMAR_5445|M.marinum_M               MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAM
MLBr_00053|M.leprae_Br4923          MTTKKFTPTITRGPRLTPGEINITPPDDLGLEIPPSGIQKILPYVMVGCI
MSMEG_0061|M.smegmatis_MC2_155      MTTKKFTPTIKRGPRLTPGEINVAPPDDLGIDIPPSGMQKALPWVMGGCM
TH_4195|M.thermoresistible__bu      MTTRKFTPTIKRGPRLTPGEINVTPPEDLGVEIPPSGVQKALPWVMGGCM
Mflv_0771|M.gilvum_PYR-GCK          MTTRKFTPIIKRGPRLTPGEINVAPPEDLGVDIPPSGMQKALPWVMGGCM
Mvan_0074|M.vanbaalenii_PYR-1       MTTRKFTPIIKRGPRLTPGEINVTPPEDLGVDIPPSGMQKALPWVMGGCM
MAV_4390|M.avium_104                ---------------MTQADIVVEAPPELPAPESTGLPARLLPVALSVAG
MUL_0860|M.ulcerans_Agy99           ----------------MTEDLVVAAPPELAQTTSTGPLLRLVPLAMSIAT
MAB_3756c|M.abscessus_ATCC_199      ---------------MPGGEVNVQPPPEIPRPVPSPIIAKIMPLVMVVAM
                                                       :: : .* ::    ..    : :* .:  . 

Rv3870|M.tuberculosis_H37Rv         LGMIAIMVAGG--------TRQLSPYMLMMPLMMIVMMVGGLAGSTGGGG
Mb3900|M.bovis_AF2122/97            LGMIAIMVAGG--------TRQLSPYMLMMPLMMIVMMVGGLAGSTGGGG
MMAR_5445|M.marinum_M               LGMIVIMVAGG--------TRQLSPYMLMMPLMMIVMMVGTLAGGSGGGS
MLBr_00053|M.leprae_Br4923          VGMIAIMVLGG--------TKQLSPYMLMMPIMMVMMMAGGSGG--GGGG
MSMEG_0061|M.smegmatis_MC2_155      LGMIAIMVFTG--------VRQLSPYMLMMPLMMIMGTVGFMAGG-GSGG
TH_4195|M.thermoresistible__bu      LGMIAIMVFTG--------IRNLSPYMLMMPLMMVMATVGFMAGG-GPGG
Mflv_0771|M.gilvum_PYR-GCK          LGMIAILIFGG--------LRNFSPYMLMMPMMVVMGAVGMMASG-GSGG
Mvan_0074|M.vanbaalenii_PYR-1       LGMIAILIFGG--------MRNFSPYMLMMPMMVVMGAVGMMAGG-GSGG
MAV_4390|M.avium_104                IGVMTVVFASG-------GAAARQPAFLAFPATMLVSTVAAALIG-RSR-
MUL_0860|M.ulcerans_Agy99           LIAMAATYVSG-------APSARNPTMLVLPATMSLSLMVMAVSA-RGR-
MAB_3756c|M.abscessus_ATCC_199      VGMIAFFVTSGSFGGGAGGGMMRSPMFMLFPIMMMVSMVSMVSNS-GGKG
                                    :  :.     *            .* :: :*  : :              

Rv3870|M.tuberculosis_H37Rv         KKVPEINADRKEYLRYLAGLRTRVTSSATSQVAFFSYHAPHPEDLLSIVG
Mb3900|M.bovis_AF2122/97            KKVPEINADRKEYLRYLAGLRTRVTSSATSQVAFFSYHAPHPEDLLSIVG
MMAR_5445|M.marinum_M               KKVPEINADRKEYLRYLAGLRGRVTTSATSQVSFFGYHAPHPDDLLSIVG
MLBr_00053|M.leprae_Br4923          KKVPEINADRKEYLRYLAGLRARVTSSAASQVAFFSYHAPHPQDLLSIVG
MSMEG_0061|M.smegmatis_MC2_155      KKVPEINADRKEYLRYLAGLRTRVTSSASAQVAFFAYHAPHPDDLLSIIG
TH_4195|M.thermoresistible__bu      KRVPEINADRKEYLRYLAGLRNRVTSSAAAQVTFFAYHAPHPDDLLSIVG
Mflv_0771|M.gilvum_PYR-GCK          KKVPEINADRKEYLRYLAGLRTRVTSSAAAQVSFFNYHAPHPDDLLSIVG
Mvan_0074|M.vanbaalenii_PYR-1       KKVPEINADRKEYLRYLAGLRTRVTSSASAQVTFFNYHGPHPDDLLSIIG
MAV_4390|M.avium_104                RGGGGLDADRGRYLEYLNQLGRSVSEIAAAQCASALRDHPDPDTLWTLIG
MUL_0860|M.ulcerans_Agy99           RRGAGLDQDRVGYLQYLSELRQRVTEIAAAQRISSNRTHPEPDTVWTLIG
MAB_3756c|M.abscessus_ATCC_199      AKTSEINEDRKDYLRYLEVVRKNVTDTGAAQRKALLWNNPDPSALWTLAG
                                         :: **  **.**  :   *:  .::*        *.*. : :: *

Rv3870|M.tuberculosis_H37Rv         TQRQWSRPANADFYAATRIGIGDQPAVDRLLKPAVGGELAAASAAPQPFL
Mb3900|M.bovis_AF2122/97            TQRQWSRPANADFYAATRIGIGDQPAVDRLLKPAVGGELAAASAAPQPFL
MMAR_5445|M.marinum_M               TQRQWSRPANSDFYAAARIGIGDQPAVDRLLKPAVGGELAASSAAPQPYL
MLBr_00053|M.leprae_Br4923          TQRQWSRPANADFYAATRIGVGDQPAVDRLLKPAVGGELTASGAAPQPFL
MSMEG_0061|M.smegmatis_MC2_155      THRQWARQANSEFFAATRIGIGAEIAVDRLLKPNTSGELAGGQAAPAPHL
TH_4195|M.thermoresistible__bu      THRQWSRQTNADFYAAVRIGIGSEPAVDRLLKPSVGAELVGPQGAPQPHL
Mflv_0771|M.gilvum_PYR-GCK          THRQWSRAANHDFYAATRIGLGSEPAVDRLLKPAVGAELAGPAGAPQPHL
Mvan_0074|M.vanbaalenii_PYR-1       THRQWSRPANHDFYAATRIGLGSEPAVDRLLKPAVGSELAGPAGAPQPHL
MAV_4390|M.avium_104                GPRMWRRRPTGPDFCVVRVGMGVLPLARRVVAPPVP---------AEEVR
MUL_0860|M.ulcerans_Agy99           GSRMWERRPADADFCRIRIGLGTQPLATRLVAAPLP---------PPHRS
MAB_3756c|M.abscessus_ATCC_199      GRRMWERRPGDSDYCHVRVGTGDQRLAAQLVAPEIG---------PVEEL
                                      * * * .    :.  *:* *    . ::: .            .    

Rv3870|M.tuberculosis_H37Rv         EPVSHMWVVKFLRTHGLIHDCPKLLQLRTFPTIAIGGDLAGAAGLMTAMI
Mb3900|M.bovis_AF2122/97            EPVSHMWVVKFLRTHGLIHDCPKLLQLRTFPTIAIGGDLAGAAGLMTAMI
MMAR_5445|M.marinum_M               EPVSHMWVVKFLRTHGLIHDCPKLVQLRSFPTIAIGGDRPGADRLLTAMI
MLBr_00053|M.leprae_Br4923          EPVSHMWVVKFLRTHGLVHDCPKLLQMRTFPTIAVGGDTAGAGGLLTAMI
MSMEG_0061|M.smegmatis_MC2_155      EPVSHMWVTKFLRTHGLIHDCPKLVQLRTFPTVAVGGDPEAAEGLLTSMI
TH_4195|M.thermoresistible__bu      EPVSHMWVTKFLRTHGLIHDCPKLVQLRTFPTIAIGGDPEGAARLLTAMI
Mflv_0771|M.gilvum_PYR-GCK          EPVSHMWVTKFLRTHGLIHDCPKLLQLRTFPTIAVGGDTDGAVGLLTAMI
Mvan_0074|M.vanbaalenii_PYR-1       EPVSHMWVTKFLRTHGLIHDCPKLVQLKTFPTIAVGGDSAGSAALLAAMI
MAV_4390|M.avium_104                DPVTATALRRFLHTHATVPG-PVTVDLGAGSPVTIDGDAGAARAVLRAVV
MUL_0860|M.ulcerans_Agy99           DPVTVSALRRFLEAHARVTDVPIAIALHGAGVVTIGGDPARVRALLRAMV
MAB_3756c|M.abscessus_ATCC_199      EPVASVALRRFVRTHSLVPELPIALNLRGFAAVTIDGSPEVARGMLRAMI
                                    :**:   : :*:.:*. :   *  : :     :::.*.      :: :::

Rv3870|M.tuberculosis_H37Rv         CHLAVFHPPDLLQIRVLTEEPDDPDWSWLKWLPHVQHQTETDAAGSTRLI
Mb3900|M.bovis_AF2122/97            CHLAVFHPPDLLQIRVLTEEPDDPDWSWLKWLPHVQHQTETDAAGSTRLI
MMAR_5445|M.marinum_M               CHLAVFHPPDLLQIRVLTEDPEDPDWSWLKWLPHVQHQTETDGAGPVRMI
MLBr_00053|M.leprae_Br4923          CHLAVFHPPDLLQIRVLTEKPDDPNWSWLKWLPHIQHPTETDAAGAARMI
MSMEG_0061|M.smegmatis_MC2_155      CHLAVFHPPDLVQIRVLTDNPEDPKWSWLKWLPHTQHQTDTDAAGPTRLV
TH_4195|M.thermoresistible__bu      CHLAVFHPPDLLQIRVLTDNPEDPEWSWIKWLPHVQHPTDTDAAGPTRMV
Mflv_0771|M.gilvum_PYR-GCK          CHLAVFHPPDMLQMRVLTDNPEDPVWAWLKWLPHLQHQTDTDAAGATRMV
Mvan_0074|M.vanbaalenii_PYR-1       CHLAVFHPPDMLQMRVLTDDPEDPAWAWLKWLPHLQHETDTDAAGTTRMV
MAV_4390|M.avium_104                CQLAVLHAPDRVGIAAVVGDGDRAHWDWLKWLPHNRHPTHDDALGPMRMV
MUL_0860|M.ulcerans_Agy99           CQMAVLHGPDQLLVAAVVSDRNRPGWEWLKWLPHNQHPSHHDEVGAERMV
MAB_3756c|M.abscessus_ATCC_199      CQLAMFHGPDQFLVAAVVNRHAAPHWDWLKWLPHSQHPSAFDGVGTSRLV
                                    *::*::* ** . : .:.     . * *:***** :* :  *  *. *::

Rv3870|M.tuberculosis_H37Rv         FTRQEGLSDLAARGPHAPDSLPGGPYVVVVDLTG-----------GKAGF
Mb3900|M.bovis_AF2122/97            FTRQEGLSDLAARGPHAPDSLPGGPYVVVVDLTG-----------GKAGF
MMAR_5445|M.marinum_M               STRPDGLADLAARGPHAPDTLPTGPYVVVLDLTG-----------GKAGF
MLBr_00053|M.leprae_Br4923          FTRSDSLADLMSRGPHAPDSLPGGPYVILVDLTG-----------GKAGF
MSMEG_0061|M.smegmatis_MC2_155      YTRPDGLSDLTARGPHTADAAPGGPYVVVVDLTG-----------GKAGF
TH_4195|M.thermoresistible__bu      FTRPDGLSDLAARGPHTADSAPSGPYVVVVDLTG-----------GKAGF
Mflv_0771|M.gilvum_PYR-GCK          FTRTDGLSDLAARGPHTADATPSGPYVVVIDLTG-----------GRAGF
Mvan_0074|M.vanbaalenii_PYR-1       FTRPDALSDLAARGPHTADAAPSGPYVVVIDLTG-----------GRAGF
MAV_4390|M.avium_104                YSTAAQAQQALAG--LPVARLVLVAERAVAPI------------------
MUL_0860|M.ulcerans_Agy99           YPNITQASAAFDAVALPVMVIVDTDEHGKQLP------------------
MAB_3756c|M.abscessus_ATCC_199      YHSLGEVEESLASLITERERFSRTAQPSPDRPQILIVVDSGTLIGSERLI
                                                                                      

Rv3870|M.tuberculosis_H37Rv         PPDGRAGVTVITLGNHRGSAYRIRVHE-DGTADDRLP-NQSFRQVTSVTD
Mb3900|M.bovis_AF2122/97            PPDGRAGVTVITLGNHRGSAYRIRVHE-DGTADDRLP-NQSFRQVTSVTD
MMAR_5445|M.marinum_M               PPDGRAGVTVITLGNHRGSAYRIRVAE-NGTADDRLP-GQQFRLVTAAAD
MLBr_00053|M.leprae_Br4923          PPDGRAGVTVITLGNHRSSTYRIRVNK-NGTADDRLP-GQSFRQVTSTVD
MSMEG_0061|M.smegmatis_MC2_155      PPDGRAGVTVITLGAQRQAAYKLKVEK-DGKAEDRLP-NQPWREVTRVAD
TH_4195|M.thermoresistible__bu      PVDGRAGVTVLTLGNHRGSNYRIRVAA-DGTADDRLP-GQSFRLVTSVAD
Mflv_0771|M.gilvum_PYR-GCK          PMDGRSGVTVLTLGNHR-STYRIRVDAGDGTADDKLP-GASFRLVASEVD
Mvan_0074|M.vanbaalenii_PYR-1       PMDGRSGVTVITLGNHR-SAYRIRVDA-DGTADDKLP-GASFRLVASQVD
MAV_4390|M.avium_104                -----AGATVIAIGAGDD------GAPVTIRT-------AAGTVSPSRPD
MUL_0860|M.ulcerans_Agy99           -----AGVTVLEVGRGPD------GTQVVVKR-------AGETTTLTRPD
MAB_3756c|M.abscessus_ATCC_199      VDHGIDSVTLVEIGTRVDPLAARRGMQLELTERGLGAKGNVGSEVFAHPD
                                          ..*:: :*                                   *

Rv3870|M.tuberculosis_H37Rv         RMSPQQASRIARKLAGWSITGTILDKTSRVQKKVATDWHQLVGAQSVEEI
Mb3900|M.bovis_AF2122/97            RMSPQQASRIARKLAGWSITGTILDKTSRVQKKVATDWHQLVGAQSVEEI
MMAR_5445|M.marinum_M               SMTPQEATRLARKLAGWSITGTILDKTQRIQKKVATEFHQLVNAKSVEDI
MLBr_00053|M.leprae_Br4923          HLSKAEATRIARKLAGWSITGTILDKTSRVQKKVATEWHQLVGANTVEEV
MSMEG_0061|M.smegmatis_MC2_155      RMTPGQAGRIARKLAGWSITGTIIDKNVRVQKKVSNEWHHLVGAQSVEEV
TH_4195|M.thermoresistible__bu      RMTPEQAGHVARKLAGWSITGTIIDKNVRVQKKVATEWHQLVGAQSVEEV
Mflv_0771|M.gilvum_PYR-GCK          RMSPAQAERLARKLAGWSITGTIIDKGTRVQKKVATEWHEIVGAQSVEEV
Mvan_0074|M.vanbaalenii_PYR-1       GMTPRQAERVARKLAGWSITGTIIDKGTRVQKKVATEWHEIVGAQSVEEV
MAV_4390|M.avium_104                RMTAADALTCARRLAGQRV--TAGDG--------DGGWPGLVGLADVSGF
MUL_0860|M.ulcerans_Agy99           ELDQVSALVCARLLAPHRCGDRAGGH--------PGDWARMLGIGEIATY
MAB_3756c|M.abscessus_ATCC_199      HLTITEAMACARRLAPYRVLTGSGDEVQ-IQTEVSTRWSDIVGIGDPGLL
                                     :   .*   ** **         .            :  ::.       

Rv3870|M.tuberculosis_H37Rv         TPSRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGAGPHGMLIG
Mb3900|M.bovis_AF2122/97            TPSRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGAGPHGMLIG
MMAR_5445|M.marinum_M               TPGRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGGGPHGMLIG
MLBr_00053|M.leprae_Br4923          LPSRWRMYTDNDRDRLKIPFGHEFKTGNIMYLDIKEGAEFGGGPHGMLIG
MSMEG_0061|M.smegmatis_MC2_155      TPARWRMYADTDRDRLKIPFGHELKTGEIMYLDIKEGAEFGAGPHGMLIG
TH_4195|M.thermoresistible__bu      TPARWRMFADTDRDRLRIPFGHELKTGEIMYLDIKEGAEFGAGPHGMLIG
Mflv_0771|M.gilvum_PYR-GCK          TPARWRMFTDTDRDRLRIPFGHELKTGDVMYLDIKEGAEFGAGPHGMLIG
Mvan_0074|M.vanbaalenii_PYR-1       TPARWRMFTDTDRDRLRIPFGHELKTGDVMYLDIKEGAEFGAGPHGMLIG
MAV_4390|M.avium_104                DPATLWGRQ-TGRDRLRAPLGVAAD-GTPVELDIKEPAEHGMGPHGLCVG
MUL_0860|M.ulcerans_Agy99           HPVSHWHKR-NQRERLCVPIGATAD-GSPVLLDIKEPAARGMGPHGLCIG
MAB_3756c|M.abscessus_ATCC_199      NPEVVWRNR-VGRDRLRVPIGIAVD-GTPMELDIKEAAENGMGPHGLCIG
                                     *          *:**  *:*   . *  : ***** *  * ****: :*

Rv3870|M.tuberculosis_H37Rv         TTGSGKSEFLRTLILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAA
Mb3900|M.bovis_AF2122/97            TTGSGKSEFLRTLILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAA
MMAR_5445|M.marinum_M               TTGSGKSEFLRTMILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAA
MLBr_00053|M.leprae_Br4923          TTGSGKSEFLRTLILSLVAMTHPNQVNLLLTDFKGGSTFLGMEKLPHTAA
MSMEG_0061|M.smegmatis_MC2_155      TTGSGKSEFLRTLILSLVATHHPDQINLLLTDFKGGSTFLGMEKLPHTAA
TH_4195|M.thermoresistible__bu      TTGSGKSEFLRTLILSLAATHHPDQVNLLLTDFKGGSTFLGMEKLPHTAA
Mflv_0771|M.gilvum_PYR-GCK          TTGSGKSEFLRTLILSLAATHHPDQINLLLTDFKGGSTFLGMEKLPHTAA
Mvan_0074|M.vanbaalenii_PYR-1       TTGSGKSEFLRTLILSLAATHHPDQINLLLTDFKGGSTFLGMEKLPHTAA
MAV_4390|M.avium_104                ATGSGKSELLRTIALGMMARNSPDVLNLLLVDFKGGATFLDYANAPHVAA
MUL_0860|M.ulcerans_Agy99           ATGSGKSELLRTVALGMMVGNSPEVLNLLLIDFKGGATFLDLEKAPHVAA
MAB_3756c|M.abscessus_ATCC_199      ATGSGKSEFLRTLTLGMIATHSPDALNLVLVDFKGGATFLGLDRAQHVAA
                                    :*******:***: *.: .   *: :**:* *****:***.  .  *.**

Rv3870|M.tuberculosis_H37Rv         VVTNMAEEAELVSRMGEVLTGELDRRQSILRQAGMKVGAAGALSGVAEYE
Mb3900|M.bovis_AF2122/97            VVTNMAEEAELVSRMGEVLTGELDRRQSILRQAGMKVGAAGALSGVAEYE
MMAR_5445|M.marinum_M               VITNMAEEAELVSRMGEVLTGELDRRQSILRQAGMKVGAAGALSGVAEYE
MLBr_00053|M.leprae_Br4923          VVTNMAEEAELVSRMGEVLTGELDRRQNILRQAGTLVGAAGALSGVAEYE
MSMEG_0061|M.smegmatis_MC2_155      VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGMQVGAAGALSGVAEYE
TH_4195|M.thermoresistible__bu      VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGMQVGAAGALSGVAEYE
Mflv_0771|M.gilvum_PYR-GCK          VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGIQVGAAGALSGVAEYE
Mvan_0074|M.vanbaalenii_PYR-1       VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGMQVGAAGALSGVAEYE
MAV_4390|M.avium_104                VITNLADDAPLVARMRAALAGEMNRRQEALR-------TAG-CDSVAAYQ
MUL_0860|M.ulcerans_Agy99           VITNLADQAPLVARMGEALAGEMNRRQHLLR-------TAGNFVSVAAYE
MAB_3756c|M.abscessus_ATCC_199      IITNLAEEANLVSRMKDALAGEMNRRQELLR-------AAGNFANVTEYE
                                    ::**: ::* **:**  .*:**::***  **       :**   .*: *:

Rv3870|M.tuberculosis_H37Rv         KYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL
Mb3900|M.bovis_AF2122/97            KYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL
MMAR_5445|M.marinum_M               KYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL
MLBr_00053|M.leprae_Br4923          KYRERGANLAPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL
MSMEG_0061|M.smegmatis_MC2_155      KHRERGADLPPLPTLFVVVDEFAELLQNHPDFINLFDRICRVGRSLRVHL
TH_4195|M.thermoresistible__bu      KYRERGADLPPLPTLFVVVDEFAELLQNHPDFINLFDRICRVGRSLRVHL
Mflv_0771|M.gilvum_PYR-GCK          KHRERGADLPPLPTLFVVVDEFAELLQNHPDFIGLFDRICRVGRSLRVHL
Mvan_0074|M.vanbaalenii_PYR-1       KHRERGADLAPLPTLFVVVDEFAELLQNHPDFIQLFDRICRVGRSLRVHL
MAV_4390|M.avium_104                HARRSAAALPALPTLFVIVDEFSELLSQQPDFADTFVAIGRLGRSLGIHL
MUL_0860|M.ulcerans_Agy99           DARRRGAGLAALPTLFIIVDEFAELLSQHPDFAEVFVAIGRLGRSLGMHL
MAB_3756c|M.abscessus_ATCC_199      RARAAGASLSPLPALFIIVDEFSELLSQHPDFAELFVAIGRLGRSLHVHL
                                      *  .* *..**:**::****:***..:***   *  * *:**** :**

Rv3870|M.tuberculosis_H37Rv         LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNK
Mb3900|M.bovis_AF2122/97            LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNK
MMAR_5445|M.marinum_M               LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNK
MLBr_00053|M.leprae_Br4923          LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK
MSMEG_0061|M.smegmatis_MC2_155      LLATQSLNTGGVRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK
TH_4195|M.thermoresistible__bu      LLATQSLNTGGVRIDKLEPNLTYRIALRTTSSTESKAVIGTPEAQYITNK
Mflv_0771|M.gilvum_PYR-GCK          LLATQSLNTGGTRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK
Mvan_0074|M.vanbaalenii_PYR-1       LLATQSLNTGGTRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK
MAV_4390|M.avium_104                LLASQRLDEG--RLRGLDAHLSYRLCLKTLSEAESRAVLGNLDAYHLPT-
MUL_0860|M.ulcerans_Agy99           LLASQRLEEG--RLRGLEAHLSYRVCLKTLSAIESRTALGTLDAFELPN-
MAB_3756c|M.abscessus_ATCC_199      LLASQRLDEG--RLRGLESHLSYRLCLKTFSANESRAAIGVPDAYHLPN-
                                    ***:* *: *  *:  *:.:*:**:.*:* *  **::.:*  :*  :.. 

Rv3870|M.tuberculosis_H37Rv         ESGVGFLRVGMEDPVKFSTFYISGPYMP----------------------
Mb3900|M.bovis_AF2122/97            ESGVGFLRVGMEDPVKFSTFYISGPYMP----------------------
MMAR_5445|M.marinum_M               ESGVGFLRVGMEDPIKFSTLYISGPYVP----------------------
MLBr_00053|M.leprae_Br4923          ESGVGFLRIGMEDPVKFSSLYTGIPFVP----------------------
MSMEG_0061|M.smegmatis_MC2_155      ESGVGFLRVGMEDPVKFRSVYTGNNYVP----------------------
TH_4195|M.thermoresistible__bu      ESGVGFLRVGMEDPVKFRTVYTGNPYVP----------------------
Mflv_0771|M.gilvum_PYR-GCK          ESGVGFLRVGMEDPVKFQSVYTGTPYVP----------------------
Mvan_0074|M.vanbaalenii_PYR-1       ESGVGFLRVGMEDPVKFQSVYTGNPYVP----------------------
MAV_4390|M.avium_104                DPGAGYLRVGAGAPIRFQAALVSGPLRPDTAPRP-------PAMVRVFGT
MUL_0860|M.ulcerans_Agy99           TPGSGLLSSPTAELTRFETAFVSGPVPAGPPDADSVAL---PAAVRPFTS
MAB_3756c|M.abscessus_ATCC_199      TPGSCYLKDDSGELTRFQTSYVSGPYVPYGPARRTVSSGGGGAAPRLFTA
                                     .*   *        :* :   .    .                      

Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3900|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4390|M.avium_104                RVVG------PVSR--PVEAAHPSGRSISAAVLDRLAGHGPAAHRVWLPP
MUL_0860|M.ulcerans_Agy99           EATG------DVRTGGADGADTATGPTVLQTVLDRIAGHGPRAHQVWLPP
MAB_3756c|M.abscessus_ATCC_199      APVALQMRPAEVVEDDSPAVSEATGRSVIDTILDRVEGHGNPAHEVWLPP
                                                                                      

Rv3870|M.tuberculosis_H37Rv         -------------------------------------------PAAGVET
Mb3900|M.bovis_AF2122/97            -------------------------------------------PAAGVET
MMAR_5445|M.marinum_M               -------------------------------------------PAT-AET
MLBr_00053|M.leprae_Br4923          -------------------------------------------AIA-TET
MSMEG_0061|M.smegmatis_MC2_155      -------------------------------------------AAP---E
TH_4195|M.thermoresistible__bu      -------------------------------------------HSS---A
Mflv_0771|M.gilvum_PYR-GCK          -------------------------------------------VTV---G
Mvan_0074|M.vanbaalenii_PYR-1       -------------------------------------------TVG---N
MAV_4390|M.avium_104                LGRPPELRTLLGG--------AADLTVPVGLVDRPFEQCRTPLIVDLSGA
MUL_0860|M.ulcerans_Agy99           LDRAPALASLLSDGAAE----HAELAVPIGVVDRPFDQSRTPLTIDLTAA
MAB_3756c|M.abscessus_ATCC_199      LDDSPTLGDLIPRHGRAGFDAVGSLTVPIGIVDRPYEQRRDPYIVDLSAA
                                                                                      

Rv3870|M.tuberculosis_H37Rv         NGEAGGPGQQTTRQAARIHRFTAAPVLEEAPTP-----------------
Mb3900|M.bovis_AF2122/97            NGEAGGPGQQTTRQAARIHRFTAAPVLEEAPTP-----------------
MMAR_5445|M.marinum_M               NGDGSGPSTQFAKRALQIREFTAAPVLEEALTP-----------------
MLBr_00053|M.leprae_Br4923          NGDSSPSSPWASRKKVHIYEFTAAPILESTTTS-----------------
MSMEG_0061|M.smegmatis_MC2_155      SSDREAKPKAQRQSQVRIHQFTTTPIFDTAVS------------------
TH_4195|M.thermoresistible__bu      SENGEARPRVPERQRVRIREFTCAPIPEAMVN------------------
Mflv_0771|M.gilvum_PYR-GCK          AGD-DDTPRAHADSGIRIHRFTTAPIADTRVTV-----------------
Mvan_0074|M.vanbaalenii_PYR-1       AGD-DEAPKAHADKNIRIHRFTTAPIMDARLG------------------
MAV_4390|M.avium_104                AGNVAVVGAPRSGKSTALRTLITALAATHDPARVQFYCLDFGGGALSSLH
MUL_0860|M.ulcerans_Agy99           AGNVAVVGAPQSGKSTTLSTLITALAATHDPDLVQFYCLDFGGGALAAVR
MAB_3756c|M.abscessus_ATCC_199      AGNVAIVGAPQSGKSMAVRTLVTSLAVTHSPAQVQFYCLDFGGGTLTSLA
                                      :              :  :  :                          

Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3900|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4390|M.avium_104                TLPHVGAVAGRAEPRRVGRIVAECEAVVGRREAFFGEHAIASIADYRQRR
MUL_0860|M.ulcerans_Agy99           DLPHVGAVAGRGEPDLIRGIVAELESCLRTRESLFGEQGIDSIAAYRRLR
MAB_3756c|M.abscessus_ATCC_199      QLPHVGSVASRLESDLIRRTFAEMLTIVRSRENAFRAYGIDSMAEYRRRK
                                                                                      

Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3900|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4390|M.avium_104                ----PGS--DPFGDVFLVIDGWAVLRRDFETLEASIIALAGQGLSFGVHL
MUL_0860|M.ulcerans_Agy99           ----ADSGAQRLADLFVVIDGWATLCHEFEELQEPITALAGQGLSYGLHV
MAB_3756c|M.abscessus_ATCC_199      GAGDPQLANDPFGDVFFIIDGWSTVRQEFEALEPQVTALAAQGLGFGVHT
                                                                                      

Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3900|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4390|M.avium_104                VLSASRWADIRPALRDQIGTRIELRLGDPADSEIDRRAAAHVPRDSPGRG
MUL_0860|M.ulcerans_Agy99           VVSATRWAHLRGSLKDQLGTRIELRLGDPADSEVDRRGARQVPRDRPGRG
MAB_3756c|M.abscessus_ATCC_199      VVTASRWAEIRPALKDQIGTRVELRLGDPLDSDFDRKLAQLVPDGRPGRG
                                                                                      

Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3900|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4390|M.avium_104                LSHDGLHMVIASP-VADVAAG------------------ESVAPPIPLLP
MUL_0860|M.ulcerans_Agy99           LCDDGMHMMIALPNVAEVVVSQ--------------QHAGSGAPAVPLLP
MAB_3756c|M.abscessus_ATCC_199      ITRDRRHMLIGLPRVDSISSNQDLGEAIAAAAASMRQRSSVEAPQVRMLP
                                                                                      

Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3900|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4390|M.avium_104                ARVDLDAVRRGS--GDEFAGRPLLGLQERQLQPLAIDFARESHLLILGAN
MUL_0860|M.ulcerans_Agy99           QRVEHRDVVEAA--GAALSGRILLGLQQRRLQPVAVDFEHHAHLLILGDN
MAB_3756c|M.abscessus_ATCC_199      HKIDYAALVPQAPQNDQPNLRILVGINESELAPTFLEFGEQPHMMIFGDS
                                                                                      

Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3900|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4390|M.avium_104                GCGKTAALRTLCRELVRTNTAAQAQLVIVDFRRALLGIVESEQLRGYAMS
MUL_0860|M.ulcerans_Agy99           ACGKSSALRTLCREITRTKTAAQARLFLVDFRRELLGLSESEYLGGHAIA
MAB_3756c|M.abscessus_ATCC_199      ECGKTALLRTMCREIVRTTTPQQAQLFIVDYRRTLLGVVETEHLAKYAMS
                                                                                      

Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3900|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4390|M.avium_104                PAALTALLPGLLDLLSGRMPPPDASQAQLRAGSWWSGPDVYVVVDDYDLV
MUL_0860|M.ulcerans_Agy99           AGGLGAFLPGLVELLRARMPAPHLSQARLRDRSWWSGPGIYLMVDDYDLE
MAB_3756c|M.abscessus_ATCC_199      SNTLVDEVPALIELLKSRMPGPDVTQQELRDRSWWSGPEIYILVDDYDLV
                                                                                      

Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3900|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4390|M.avium_104                ASPSGNLLAPLVEFLPYASELGLHLIIARRSGGAERAMFEPLLAGLRDLG
MUL_0860|M.ulcerans_Agy99           CTSASNPLLALLEYLPYATDLGLHLIVASRSGGATRALFEPLLAALRDFG
MAB_3756c|M.abscessus_ATCC_199      ALASGNPLLPLAEYLPHSKDIGLHVVIARRTSGASRAMFEPMMARMKDLS
                                                                                      

Rv3870|M.tuberculosis_H37Rv         -------------------------------------------------
Mb3900|M.bovis_AF2122/97            -------------------------------------------------
MMAR_5445|M.marinum_M               -------------------------------------------------
MLBr_00053|M.leprae_Br4923          -------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      -------------------------------------------------
TH_4195|M.thermoresistible__bu      -------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          -------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       -------------------------------------------------
MAV_4390|M.avium_104                CMSLTMS----EAAPFAAAP--PLPPGRGVLTTRAGADELVQVAWSPP-
MUL_0860|M.ulcerans_Agy99           CMALMMSGRCDEGPLFGSGRPMPLPPGRAVLVTWAGDERLVQVAWTEPG
MAB_3756c|M.abscessus_ATCC_199      CIGLQMSGNKDEGVLLGTVRPSEQPPGRGTLVMRSGGQQLIQVAWSEPQ