For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TTKKFTPTITRGPRLTPGEINITPPDDLGLEIPPSGIQKILPYVMVGCIVGMIAIMVLGGTKQLSPYMLM MPIMMVMMMAGGSGGGGGGKKVPEINADRKEYLRYLAGLRARVTSSAASQVAFFSYHAPHPQDLLSIVGT QRQWSRPANADFYAATRIGVGDQPAVDRLLKPAVGGELTASGAAPQPFLEPVSHMWVVKFLRTHGLVHDC PKLLQMRTFPTIAVGGDTAGAGGLLTAMICHLAVFHPPDLLQIRVLTEKPDDPNWSWLKWLPHIQHPTET DAAGAARMIFTRSDSLADLMSRGPHAPDSLPGGPYVILVDLTGGKAGFPPDGRAGVTVITLGNHRSSTYR IRVNKNGTADDRLPGQSFRQVTSTVDHLSKAEATRIARKLAGWSITGTILDKTSRVQKKVATEWHQLVGA NTVEEVLPSRWRMYTDNDRDRLKIPFGHEFKTGNIMYLDIKEGAEFGGGPHGMLIGTTGSGKSEFLRTLI LSLVAMTHPNQVNLLLTDFKGGSTFLGMEKLPHTAAVVTNMAEEAELVSRMGEVLTGELDRRQNILRQAG TLVGAAGALSGVAEYEKYRERGANLAPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHLLLAT QSLQTGGVRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNKESGVGFLRIGMEDPVKFSSLYTGI PFVPAIATETNGDSSPSSPWASRKKVHIYEFTAAPILESTTTS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00053 | - | - | 100% (744) | hypothetical protein MLBr_00053 |
| M. leprae Br4923 | MLBr_02535 | - | 7e-92 | 32.41% (725) | hypothetical protein MLBr_02535 |
| M. leprae Br4923 | MLBr_01543 | - | 6e-75 | 29.73% (693) | putative SpoIIIE-family membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3900 | - | 0.0 | 85.39% (746) | hypothetical protein Mb3900 |
| M. gilvum PYR-GCK | Mflv_0771 | - | 0.0 | 78.12% (745) | cell divisionFtsK/SpoIIIE |
| M. tuberculosis H37Rv | Rv3870 | - | 0.0 | 85.39% (746) | transmembrane protein |
| M. abscessus ATCC 19977 | MAB_3756c | - | 1e-133 | 40.28% (710) | putative FtsK/SpoIIIE family protein |
| M. marinum M | MMAR_5445 | - | 0.0 | 83.09% (745) | hypothetical protein MMAR_5445 |
| M. avium 104 | MAV_4390 | - | 1e-102 | 36.31% (705) | ftsk/SpoIIIE family protein |
| M. smegmatis MC2 155 | MSMEG_0061 | - | 0.0 | 76.61% (744) | ftsk/SpoIIIE family protein |
| M. thermoresistible (build 8) | TH_4195 | - | 0.0 | 79.89% (741) | PUTATIVE cell divisionFtsK/SpoIIIE |
| M. ulcerans Agy99 | MUL_0860 | - | 1e-108 | 35.98% (706) | hypothetical protein MUL_0860 |
| M. vanbaalenii PYR-1 | Mvan_0074 | - | 0.0 | 77.33% (741) | cell divisionFtsK/SpoIIIE |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3900|M.bovis_AF2122/97 MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAM
Rv3870|M.tuberculosis_H37Rv MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAM
MMAR_5445|M.marinum_M MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAM
MLBr_00053|M.leprae_Br4923 MTTKKFTPTITRGPRLTPGEINITPPDDLGLEIPPSGIQKILPYVMVGCI
MSMEG_0061|M.smegmatis_MC2_155 MTTKKFTPTIKRGPRLTPGEINVAPPDDLGIDIPPSGMQKALPWVMGGCM
TH_4195|M.thermoresistible__bu MTTRKFTPTIKRGPRLTPGEINVTPPEDLGVEIPPSGVQKALPWVMGGCM
Mflv_0771|M.gilvum_PYR-GCK MTTRKFTPIIKRGPRLTPGEINVAPPEDLGVDIPPSGMQKALPWVMGGCM
Mvan_0074|M.vanbaalenii_PYR-1 MTTRKFTPIIKRGPRLTPGEINVTPPEDLGVDIPPSGMQKALPWVMGGCM
MAV_4390|M.avium_104 ---------------MTQADIVVEAPPELPAPESTGLPARLLPVALSVAG
MUL_0860|M.ulcerans_Agy99 ----------------MTEDLVVAAPPELAQTTSTGPLLRLVPLAMSIAT
MAB_3756c|M.abscessus_ATCC_199 ---------------MPGGEVNVQPPPEIPRPVPSPIIAKIMPLVMVVAM
:: : .* :: .. : :* .: .
Mb3900|M.bovis_AF2122/97 LGMIAIMVAGG--------TRQLSPYMLMMPLMMIVMMVGGLAGSTGGGG
Rv3870|M.tuberculosis_H37Rv LGMIAIMVAGG--------TRQLSPYMLMMPLMMIVMMVGGLAGSTGGGG
MMAR_5445|M.marinum_M LGMIVIMVAGG--------TRQLSPYMLMMPLMMIVMMVGTLAGGSGGGS
MLBr_00053|M.leprae_Br4923 VGMIAIMVLGG--------TKQLSPYMLMMPIMMVMMMAGGSGG--GGGG
MSMEG_0061|M.smegmatis_MC2_155 LGMIAIMVFTG--------VRQLSPYMLMMPLMMIMGTVGFMAGG-GSGG
TH_4195|M.thermoresistible__bu LGMIAIMVFTG--------IRNLSPYMLMMPLMMVMATVGFMAGG-GPGG
Mflv_0771|M.gilvum_PYR-GCK LGMIAILIFGG--------LRNFSPYMLMMPMMVVMGAVGMMASG-GSGG
Mvan_0074|M.vanbaalenii_PYR-1 LGMIAILIFGG--------MRNFSPYMLMMPMMVVMGAVGMMAGG-GSGG
MAV_4390|M.avium_104 IGVMTVVFASG-------GAAARQPAFLAFPATMLVSTVAAALIG-RSR-
MUL_0860|M.ulcerans_Agy99 LIAMAATYVSG-------APSARNPTMLVLPATMSLSLMVMAVSA-RGR-
MAB_3756c|M.abscessus_ATCC_199 VGMIAFFVTSGSFGGGAGGGMMRSPMFMLFPIMMMVSMVSMVSNS-GGKG
: :. * .* :: :* : :
Mb3900|M.bovis_AF2122/97 KKVPEINADRKEYLRYLAGLRTRVTSSATSQVAFFSYHAPHPEDLLSIVG
Rv3870|M.tuberculosis_H37Rv KKVPEINADRKEYLRYLAGLRTRVTSSATSQVAFFSYHAPHPEDLLSIVG
MMAR_5445|M.marinum_M KKVPEINADRKEYLRYLAGLRGRVTTSATSQVSFFGYHAPHPDDLLSIVG
MLBr_00053|M.leprae_Br4923 KKVPEINADRKEYLRYLAGLRARVTSSAASQVAFFSYHAPHPQDLLSIVG
MSMEG_0061|M.smegmatis_MC2_155 KKVPEINADRKEYLRYLAGLRTRVTSSASAQVAFFAYHAPHPDDLLSIIG
TH_4195|M.thermoresistible__bu KRVPEINADRKEYLRYLAGLRNRVTSSAAAQVTFFAYHAPHPDDLLSIVG
Mflv_0771|M.gilvum_PYR-GCK KKVPEINADRKEYLRYLAGLRTRVTSSAAAQVSFFNYHAPHPDDLLSIVG
Mvan_0074|M.vanbaalenii_PYR-1 KKVPEINADRKEYLRYLAGLRTRVTSSASAQVTFFNYHGPHPDDLLSIIG
MAV_4390|M.avium_104 RGGGGLDADRGRYLEYLNQLGRSVSEIAAAQCASALRDHPDPDTLWTLIG
MUL_0860|M.ulcerans_Agy99 RRGAGLDQDRVGYLQYLSELRQRVTEIAAAQRISSNRTHPEPDTVWTLIG
MAB_3756c|M.abscessus_ATCC_199 AKTSEINEDRKDYLRYLEVVRKNVTDTGAAQRKALLWNNPDPSALWTLAG
:: ** **.** : *: .::* *.*. : :: *
Mb3900|M.bovis_AF2122/97 TQRQWSRPANADFYAATRIGIGDQPAVDRLLKPAVGGELAAASAAPQPFL
Rv3870|M.tuberculosis_H37Rv TQRQWSRPANADFYAATRIGIGDQPAVDRLLKPAVGGELAAASAAPQPFL
MMAR_5445|M.marinum_M TQRQWSRPANSDFYAAARIGIGDQPAVDRLLKPAVGGELAASSAAPQPYL
MLBr_00053|M.leprae_Br4923 TQRQWSRPANADFYAATRIGVGDQPAVDRLLKPAVGGELTASGAAPQPFL
MSMEG_0061|M.smegmatis_MC2_155 THRQWARQANSEFFAATRIGIGAEIAVDRLLKPNTSGELAGGQAAPAPHL
TH_4195|M.thermoresistible__bu THRQWSRQTNADFYAAVRIGIGSEPAVDRLLKPSVGAELVGPQGAPQPHL
Mflv_0771|M.gilvum_PYR-GCK THRQWSRAANHDFYAATRIGLGSEPAVDRLLKPAVGAELAGPAGAPQPHL
Mvan_0074|M.vanbaalenii_PYR-1 THRQWSRPANHDFYAATRIGLGSEPAVDRLLKPAVGSELAGPAGAPQPHL
MAV_4390|M.avium_104 GPRMWRRRPTGPDFCVVRVGMGVLPLARRVVAPPVP---------AEEVR
MUL_0860|M.ulcerans_Agy99 GSRMWERRPADADFCRIRIGLGTQPLATRLVAAPLP---------PPHRS
MAB_3756c|M.abscessus_ATCC_199 GRRMWERRPGDSDYCHVRVGTGDQRLAAQLVAPEIG---------PVEEL
* * * . :. *:* * . ::: . .
Mb3900|M.bovis_AF2122/97 EPVSHMWVVKFLRTHGLIHDCPKLLQLRTFPTIAIGGDLAGAAGLMTAMI
Rv3870|M.tuberculosis_H37Rv EPVSHMWVVKFLRTHGLIHDCPKLLQLRTFPTIAIGGDLAGAAGLMTAMI
MMAR_5445|M.marinum_M EPVSHMWVVKFLRTHGLIHDCPKLVQLRSFPTIAIGGDRPGADRLLTAMI
MLBr_00053|M.leprae_Br4923 EPVSHMWVVKFLRTHGLVHDCPKLLQMRTFPTIAVGGDTAGAGGLLTAMI
MSMEG_0061|M.smegmatis_MC2_155 EPVSHMWVTKFLRTHGLIHDCPKLVQLRTFPTVAVGGDPEAAEGLLTSMI
TH_4195|M.thermoresistible__bu EPVSHMWVTKFLRTHGLIHDCPKLVQLRTFPTIAIGGDPEGAARLLTAMI
Mflv_0771|M.gilvum_PYR-GCK EPVSHMWVTKFLRTHGLIHDCPKLLQLRTFPTIAVGGDTDGAVGLLTAMI
Mvan_0074|M.vanbaalenii_PYR-1 EPVSHMWVTKFLRTHGLIHDCPKLVQLKTFPTIAVGGDSAGSAALLAAMI
MAV_4390|M.avium_104 DPVTATALRRFLHTHATVPG-PVTVDLGAGSPVTIDGDAGAARAVLRAVV
MUL_0860|M.ulcerans_Agy99 DPVTVSALRRFLEAHARVTDVPIAIALHGAGVVTIGGDPARVRALLRAMV
MAB_3756c|M.abscessus_ATCC_199 EPVASVALRRFVRTHSLVPELPIALNLRGFAAVTIDGSPEVARGMLRAMI
:**: : :*:.:*. : * : : :::.*. :: :::
Mb3900|M.bovis_AF2122/97 CHLAVFHPPDLLQIRVLTEEPDDPDWSWLKWLPHVQHQTETDAAGSTRLI
Rv3870|M.tuberculosis_H37Rv CHLAVFHPPDLLQIRVLTEEPDDPDWSWLKWLPHVQHQTETDAAGSTRLI
MMAR_5445|M.marinum_M CHLAVFHPPDLLQIRVLTEDPEDPDWSWLKWLPHVQHQTETDGAGPVRMI
MLBr_00053|M.leprae_Br4923 CHLAVFHPPDLLQIRVLTEKPDDPNWSWLKWLPHIQHPTETDAAGAARMI
MSMEG_0061|M.smegmatis_MC2_155 CHLAVFHPPDLVQIRVLTDNPEDPKWSWLKWLPHTQHQTDTDAAGPTRLV
TH_4195|M.thermoresistible__bu CHLAVFHPPDLLQIRVLTDNPEDPEWSWIKWLPHVQHPTDTDAAGPTRMV
Mflv_0771|M.gilvum_PYR-GCK CHLAVFHPPDMLQMRVLTDNPEDPVWAWLKWLPHLQHQTDTDAAGATRMV
Mvan_0074|M.vanbaalenii_PYR-1 CHLAVFHPPDMLQMRVLTDDPEDPAWAWLKWLPHLQHETDTDAAGTTRMV
MAV_4390|M.avium_104 CQLAVLHAPDRVGIAAVVGDGDRAHWDWLKWLPHNRHPTHDDALGPMRMV
MUL_0860|M.ulcerans_Agy99 CQMAVLHGPDQLLVAAVVSDRNRPGWEWLKWLPHNQHPSHHDEVGAERMV
MAB_3756c|M.abscessus_ATCC_199 CQLAMFHGPDQFLVAAVVNRHAAPHWDWLKWLPHSQHPSAFDGVGTSRLV
*::*::* ** . : .:. . * *:***** :* : * *. *::
Mb3900|M.bovis_AF2122/97 FTRQEGLSDLAARGPHAPDSLPGGPYVVVVDLTG-----------GKAGF
Rv3870|M.tuberculosis_H37Rv FTRQEGLSDLAARGPHAPDSLPGGPYVVVVDLTG-----------GKAGF
MMAR_5445|M.marinum_M STRPDGLADLAARGPHAPDTLPTGPYVVVLDLTG-----------GKAGF
MLBr_00053|M.leprae_Br4923 FTRSDSLADLMSRGPHAPDSLPGGPYVILVDLTG-----------GKAGF
MSMEG_0061|M.smegmatis_MC2_155 YTRPDGLSDLTARGPHTADAAPGGPYVVVVDLTG-----------GKAGF
TH_4195|M.thermoresistible__bu FTRPDGLSDLAARGPHTADSAPSGPYVVVVDLTG-----------GKAGF
Mflv_0771|M.gilvum_PYR-GCK FTRTDGLSDLAARGPHTADATPSGPYVVVIDLTG-----------GRAGF
Mvan_0074|M.vanbaalenii_PYR-1 FTRPDALSDLAARGPHTADAAPSGPYVVVIDLTG-----------GRAGF
MAV_4390|M.avium_104 YSTAAQAQQALAG--LPVARLVLVAERAVAPI------------------
MUL_0860|M.ulcerans_Agy99 YPNITQASAAFDAVALPVMVIVDTDEHGKQLP------------------
MAB_3756c|M.abscessus_ATCC_199 YHSLGEVEESLASLITERERFSRTAQPSPDRPQILIVVDSGTLIGSERLI
Mb3900|M.bovis_AF2122/97 PPDGRAGVTVITLGNHRGSAYRIRVHE-DGTADDRLP-NQSFRQVTSVTD
Rv3870|M.tuberculosis_H37Rv PPDGRAGVTVITLGNHRGSAYRIRVHE-DGTADDRLP-NQSFRQVTSVTD
MMAR_5445|M.marinum_M PPDGRAGVTVITLGNHRGSAYRIRVAE-NGTADDRLP-GQQFRLVTAAAD
MLBr_00053|M.leprae_Br4923 PPDGRAGVTVITLGNHRSSTYRIRVNK-NGTADDRLP-GQSFRQVTSTVD
MSMEG_0061|M.smegmatis_MC2_155 PPDGRAGVTVITLGAQRQAAYKLKVEK-DGKAEDRLP-NQPWREVTRVAD
TH_4195|M.thermoresistible__bu PVDGRAGVTVLTLGNHRGSNYRIRVAA-DGTADDRLP-GQSFRLVTSVAD
Mflv_0771|M.gilvum_PYR-GCK PMDGRSGVTVLTLGNHR-STYRIRVDAGDGTADDKLP-GASFRLVASEVD
Mvan_0074|M.vanbaalenii_PYR-1 PMDGRSGVTVITLGNHR-SAYRIRVDA-DGTADDKLP-GASFRLVASQVD
MAV_4390|M.avium_104 -----AGATVIAIGAGDD------GAPVTIRT-------AAGTVSPSRPD
MUL_0860|M.ulcerans_Agy99 -----AGVTVLEVGRGPD------GTQVVVKR-------AGETTTLTRPD
MAB_3756c|M.abscessus_ATCC_199 VDHGIDSVTLVEIGTRVDPLAARRGMQLELTERGLGAKGNVGSEVFAHPD
..*:: :* *
Mb3900|M.bovis_AF2122/97 RMSPQQASRIARKLAGWSITGTILDKTSRVQKKVATDWHQLVGAQSVEEI
Rv3870|M.tuberculosis_H37Rv RMSPQQASRIARKLAGWSITGTILDKTSRVQKKVATDWHQLVGAQSVEEI
MMAR_5445|M.marinum_M SMTPQEATRLARKLAGWSITGTILDKTQRIQKKVATEFHQLVNAKSVEDI
MLBr_00053|M.leprae_Br4923 HLSKAEATRIARKLAGWSITGTILDKTSRVQKKVATEWHQLVGANTVEEV
MSMEG_0061|M.smegmatis_MC2_155 RMTPGQAGRIARKLAGWSITGTIIDKNVRVQKKVSNEWHHLVGAQSVEEV
TH_4195|M.thermoresistible__bu RMTPEQAGHVARKLAGWSITGTIIDKNVRVQKKVATEWHQLVGAQSVEEV
Mflv_0771|M.gilvum_PYR-GCK RMSPAQAERLARKLAGWSITGTIIDKGTRVQKKVATEWHEIVGAQSVEEV
Mvan_0074|M.vanbaalenii_PYR-1 GMTPRQAERVARKLAGWSITGTIIDKGTRVQKKVATEWHEIVGAQSVEEV
MAV_4390|M.avium_104 RMTAADALTCARRLAGQRV--TAGDG--------DGGWPGLVGLADVSGF
MUL_0860|M.ulcerans_Agy99 ELDQVSALVCARLLAPHRCGDRAGGH--------PGDWARMLGIGEIATY
MAB_3756c|M.abscessus_ATCC_199 HLTITEAMACARRLAPYRVLTGSGDEVQ-IQTEVSTRWSDIVGIGDPGLL
: .* ** ** . : ::.
Mb3900|M.bovis_AF2122/97 TPSRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGAGPHGMLIG
Rv3870|M.tuberculosis_H37Rv TPSRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGAGPHGMLIG
MMAR_5445|M.marinum_M TPGRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGGGPHGMLIG
MLBr_00053|M.leprae_Br4923 LPSRWRMYTDNDRDRLKIPFGHEFKTGNIMYLDIKEGAEFGGGPHGMLIG
MSMEG_0061|M.smegmatis_MC2_155 TPARWRMYADTDRDRLKIPFGHELKTGEIMYLDIKEGAEFGAGPHGMLIG
TH_4195|M.thermoresistible__bu TPARWRMFADTDRDRLRIPFGHELKTGEIMYLDIKEGAEFGAGPHGMLIG
Mflv_0771|M.gilvum_PYR-GCK TPARWRMFTDTDRDRLRIPFGHELKTGDVMYLDIKEGAEFGAGPHGMLIG
Mvan_0074|M.vanbaalenii_PYR-1 TPARWRMFTDTDRDRLRIPFGHELKTGDVMYLDIKEGAEFGAGPHGMLIG
MAV_4390|M.avium_104 DPATLWGRQ-TGRDRLRAPLGVAAD-GTPVELDIKEPAEHGMGPHGLCVG
MUL_0860|M.ulcerans_Agy99 HPVSHWHKR-NQRERLCVPIGATAD-GSPVLLDIKEPAARGMGPHGLCIG
MAB_3756c|M.abscessus_ATCC_199 NPEVVWRNR-VGRDRLRVPIGIAVD-GTPMELDIKEAAENGMGPHGLCIG
* *:** *:* . * : ***** * * ****: :*
Mb3900|M.bovis_AF2122/97 TTGSGKSEFLRTLILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAA
Rv3870|M.tuberculosis_H37Rv TTGSGKSEFLRTLILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAA
MMAR_5445|M.marinum_M TTGSGKSEFLRTMILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAA
MLBr_00053|M.leprae_Br4923 TTGSGKSEFLRTLILSLVAMTHPNQVNLLLTDFKGGSTFLGMEKLPHTAA
MSMEG_0061|M.smegmatis_MC2_155 TTGSGKSEFLRTLILSLVATHHPDQINLLLTDFKGGSTFLGMEKLPHTAA
TH_4195|M.thermoresistible__bu TTGSGKSEFLRTLILSLAATHHPDQVNLLLTDFKGGSTFLGMEKLPHTAA
Mflv_0771|M.gilvum_PYR-GCK TTGSGKSEFLRTLILSLAATHHPDQINLLLTDFKGGSTFLGMEKLPHTAA
Mvan_0074|M.vanbaalenii_PYR-1 TTGSGKSEFLRTLILSLAATHHPDQINLLLTDFKGGSTFLGMEKLPHTAA
MAV_4390|M.avium_104 ATGSGKSELLRTIALGMMARNSPDVLNLLLVDFKGGATFLDYANAPHVAA
MUL_0860|M.ulcerans_Agy99 ATGSGKSELLRTVALGMMVGNSPEVLNLLLIDFKGGATFLDLEKAPHVAA
MAB_3756c|M.abscessus_ATCC_199 ATGSGKSEFLRTLTLGMIATHSPDALNLVLVDFKGGATFLGLDRAQHVAA
:*******:***: *.: . *: :**:* *****:***. . *.**
Mb3900|M.bovis_AF2122/97 VVTNMAEEAELVSRMGEVLTGELDRRQSILRQAGMKVGAAGALSGVAEYE
Rv3870|M.tuberculosis_H37Rv VVTNMAEEAELVSRMGEVLTGELDRRQSILRQAGMKVGAAGALSGVAEYE
MMAR_5445|M.marinum_M VITNMAEEAELVSRMGEVLTGELDRRQSILRQAGMKVGAAGALSGVAEYE
MLBr_00053|M.leprae_Br4923 VVTNMAEEAELVSRMGEVLTGELDRRQNILRQAGTLVGAAGALSGVAEYE
MSMEG_0061|M.smegmatis_MC2_155 VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGMQVGAAGALSGVAEYE
TH_4195|M.thermoresistible__bu VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGMQVGAAGALSGVAEYE
Mflv_0771|M.gilvum_PYR-GCK VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGIQVGAAGALSGVAEYE
Mvan_0074|M.vanbaalenii_PYR-1 VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGMQVGAAGALSGVAEYE
MAV_4390|M.avium_104 VITNLADDAPLVARMRAALAGEMNRRQEALR-------TAG-CDSVAAYQ
MUL_0860|M.ulcerans_Agy99 VITNLADQAPLVARMGEALAGEMNRRQHLLR-------TAGNFVSVAAYE
MAB_3756c|M.abscessus_ATCC_199 IITNLAEEANLVSRMKDALAGEMNRRQELLR-------AAGNFANVTEYE
::**: ::* **:** .*:**::*** ** :** .*: *:
Mb3900|M.bovis_AF2122/97 KYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL
Rv3870|M.tuberculosis_H37Rv KYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL
MMAR_5445|M.marinum_M KYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL
MLBr_00053|M.leprae_Br4923 KYRERGANLAPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL
MSMEG_0061|M.smegmatis_MC2_155 KHRERGADLPPLPTLFVVVDEFAELLQNHPDFINLFDRICRVGRSLRVHL
TH_4195|M.thermoresistible__bu KYRERGADLPPLPTLFVVVDEFAELLQNHPDFINLFDRICRVGRSLRVHL
Mflv_0771|M.gilvum_PYR-GCK KHRERGADLPPLPTLFVVVDEFAELLQNHPDFIGLFDRICRVGRSLRVHL
Mvan_0074|M.vanbaalenii_PYR-1 KHRERGADLAPLPTLFVVVDEFAELLQNHPDFIQLFDRICRVGRSLRVHL
MAV_4390|M.avium_104 HARRSAAALPALPTLFVIVDEFSELLSQQPDFADTFVAIGRLGRSLGIHL
MUL_0860|M.ulcerans_Agy99 DARRRGAGLAALPTLFIIVDEFAELLSQHPDFAEVFVAIGRLGRSLGMHL
MAB_3756c|M.abscessus_ATCC_199 RARAAGASLSPLPALFIIVDEFSELLSQHPDFAELFVAIGRLGRSLHVHL
* .* *..**:**::****:***..:*** * * *:**** :**
Mb3900|M.bovis_AF2122/97 LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNK
Rv3870|M.tuberculosis_H37Rv LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNK
MMAR_5445|M.marinum_M LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNK
MLBr_00053|M.leprae_Br4923 LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK
MSMEG_0061|M.smegmatis_MC2_155 LLATQSLNTGGVRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK
TH_4195|M.thermoresistible__bu LLATQSLNTGGVRIDKLEPNLTYRIALRTTSSTESKAVIGTPEAQYITNK
Mflv_0771|M.gilvum_PYR-GCK LLATQSLNTGGTRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK
Mvan_0074|M.vanbaalenii_PYR-1 LLATQSLNTGGTRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK
MAV_4390|M.avium_104 LLASQRLDEG--RLRGLDAHLSYRLCLKTLSEAESRAVLGNLDAYHLPT-
MUL_0860|M.ulcerans_Agy99 LLASQRLEEG--RLRGLEAHLSYRVCLKTLSAIESRTALGTLDAFELPN-
MAB_3756c|M.abscessus_ATCC_199 LLASQRLDEG--RLRGLESHLSYRLCLKTFSANESRAAIGVPDAYHLPN-
***:* *: * *: *:.:*:**:.*:* * **::.:* :* :..
Mb3900|M.bovis_AF2122/97 ESGVGFLRVGMEDPVKFSTFYISGPYMP----------------------
Rv3870|M.tuberculosis_H37Rv ESGVGFLRVGMEDPVKFSTFYISGPYMP----------------------
MMAR_5445|M.marinum_M ESGVGFLRVGMEDPIKFSTLYISGPYVP----------------------
MLBr_00053|M.leprae_Br4923 ESGVGFLRIGMEDPVKFSSLYTGIPFVP----------------------
MSMEG_0061|M.smegmatis_MC2_155 ESGVGFLRVGMEDPVKFRSVYTGNNYVP----------------------
TH_4195|M.thermoresistible__bu ESGVGFLRVGMEDPVKFRTVYTGNPYVP----------------------
Mflv_0771|M.gilvum_PYR-GCK ESGVGFLRVGMEDPVKFQSVYTGTPYVP----------------------
Mvan_0074|M.vanbaalenii_PYR-1 ESGVGFLRVGMEDPVKFQSVYTGNPYVP----------------------
MAV_4390|M.avium_104 DPGAGYLRVGAGAPIRFQAALVSGPLRPDTAPRP-------PAMVRVFGT
MUL_0860|M.ulcerans_Agy99 TPGSGLLSSPTAELTRFETAFVSGPVPAGPPDADSVAL---PAAVRPFTS
MAB_3756c|M.abscessus_ATCC_199 TPGSCYLKDDSGELTRFQTSYVSGPYVPYGPARRTVSSGGGGAAPRLFTA
.* * :* : . .
Mb3900|M.bovis_AF2122/97 --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5445|M.marinum_M --------------------------------------------------
MLBr_00053|M.leprae_Br4923 --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155 --------------------------------------------------
TH_4195|M.thermoresistible__bu --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 RVVG------PVSR--PVEAAHPSGRSISAAVLDRLAGHGPAAHRVWLPP
MUL_0860|M.ulcerans_Agy99 EATG------DVRTGGADGADTATGPTVLQTVLDRIAGHGPRAHQVWLPP
MAB_3756c|M.abscessus_ATCC_199 APVALQMRPAEVVEDDSPAVSEATGRSVIDTILDRVEGHGNPAHEVWLPP
Mb3900|M.bovis_AF2122/97 -------------------------------------------PAAGVET
Rv3870|M.tuberculosis_H37Rv -------------------------------------------PAAGVET
MMAR_5445|M.marinum_M -------------------------------------------PAT-AET
MLBr_00053|M.leprae_Br4923 -------------------------------------------AIA-TET
MSMEG_0061|M.smegmatis_MC2_155 -------------------------------------------AAP---E
TH_4195|M.thermoresistible__bu -------------------------------------------HSS---A
Mflv_0771|M.gilvum_PYR-GCK -------------------------------------------VTV---G
Mvan_0074|M.vanbaalenii_PYR-1 -------------------------------------------TVG---N
MAV_4390|M.avium_104 LGRPPELRTLLGG--------AADLTVPVGLVDRPFEQCRTPLIVDLSGA
MUL_0860|M.ulcerans_Agy99 LDRAPALASLLSDGAAE----HAELAVPIGVVDRPFDQSRTPLTIDLTAA
MAB_3756c|M.abscessus_ATCC_199 LDDSPTLGDLIPRHGRAGFDAVGSLTVPIGIVDRPYEQRRDPYIVDLSAA
Mb3900|M.bovis_AF2122/97 NGEAGGPGQQTTRQAARIHRFTAAPVLEEAPTP-----------------
Rv3870|M.tuberculosis_H37Rv NGEAGGPGQQTTRQAARIHRFTAAPVLEEAPTP-----------------
MMAR_5445|M.marinum_M NGDGSGPSTQFAKRALQIREFTAAPVLEEALTP-----------------
MLBr_00053|M.leprae_Br4923 NGDSSPSSPWASRKKVHIYEFTAAPILESTTTS-----------------
MSMEG_0061|M.smegmatis_MC2_155 SSDREAKPKAQRQSQVRIHQFTTTPIFDTAVS------------------
TH_4195|M.thermoresistible__bu SENGEARPRVPERQRVRIREFTCAPIPEAMVN------------------
Mflv_0771|M.gilvum_PYR-GCK AGD-DDTPRAHADSGIRIHRFTTAPIADTRVTV-----------------
Mvan_0074|M.vanbaalenii_PYR-1 AGD-DEAPKAHADKNIRIHRFTTAPIMDARLG------------------
MAV_4390|M.avium_104 AGNVAVVGAPRSGKSTALRTLITALAATHDPARVQFYCLDFGGGALSSLH
MUL_0860|M.ulcerans_Agy99 AGNVAVVGAPQSGKSTTLSTLITALAATHDPDLVQFYCLDFGGGALAAVR
MAB_3756c|M.abscessus_ATCC_199 AGNVAIVGAPQSGKSMAVRTLVTSLAVTHSPAQVQFYCLDFGGGTLTSLA
: : : :
Mb3900|M.bovis_AF2122/97 --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5445|M.marinum_M --------------------------------------------------
MLBr_00053|M.leprae_Br4923 --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155 --------------------------------------------------
TH_4195|M.thermoresistible__bu --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 TLPHVGAVAGRAEPRRVGRIVAECEAVVGRREAFFGEHAIASIADYRQRR
MUL_0860|M.ulcerans_Agy99 DLPHVGAVAGRGEPDLIRGIVAELESCLRTRESLFGEQGIDSIAAYRRLR
MAB_3756c|M.abscessus_ATCC_199 QLPHVGSVASRLESDLIRRTFAEMLTIVRSRENAFRAYGIDSMAEYRRRK
Mb3900|M.bovis_AF2122/97 --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5445|M.marinum_M --------------------------------------------------
MLBr_00053|M.leprae_Br4923 --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155 --------------------------------------------------
TH_4195|M.thermoresistible__bu --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 ----PGS--DPFGDVFLVIDGWAVLRRDFETLEASIIALAGQGLSFGVHL
MUL_0860|M.ulcerans_Agy99 ----ADSGAQRLADLFVVIDGWATLCHEFEELQEPITALAGQGLSYGLHV
MAB_3756c|M.abscessus_ATCC_199 GAGDPQLANDPFGDVFFIIDGWSTVRQEFEALEPQVTALAAQGLGFGVHT
Mb3900|M.bovis_AF2122/97 --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5445|M.marinum_M --------------------------------------------------
MLBr_00053|M.leprae_Br4923 --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155 --------------------------------------------------
TH_4195|M.thermoresistible__bu --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 VLSASRWADIRPALRDQIGTRIELRLGDPADSEIDRRAAAHVPRDSPGRG
MUL_0860|M.ulcerans_Agy99 VVSATRWAHLRGSLKDQLGTRIELRLGDPADSEVDRRGARQVPRDRPGRG
MAB_3756c|M.abscessus_ATCC_199 VVTASRWAEIRPALKDQIGTRVELRLGDPLDSDFDRKLAQLVPDGRPGRG
Mb3900|M.bovis_AF2122/97 --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5445|M.marinum_M --------------------------------------------------
MLBr_00053|M.leprae_Br4923 --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155 --------------------------------------------------
TH_4195|M.thermoresistible__bu --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 LSHDGLHMVIASP-VADVAAG------------------ESVAPPIPLLP
MUL_0860|M.ulcerans_Agy99 LCDDGMHMMIALPNVAEVVVSQ--------------QHAGSGAPAVPLLP
MAB_3756c|M.abscessus_ATCC_199 ITRDRRHMLIGLPRVDSISSNQDLGEAIAAAAASMRQRSSVEAPQVRMLP
Mb3900|M.bovis_AF2122/97 --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5445|M.marinum_M --------------------------------------------------
MLBr_00053|M.leprae_Br4923 --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155 --------------------------------------------------
TH_4195|M.thermoresistible__bu --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 ARVDLDAVRRGS--GDEFAGRPLLGLQERQLQPLAIDFARESHLLILGAN
MUL_0860|M.ulcerans_Agy99 QRVEHRDVVEAA--GAALSGRILLGLQQRRLQPVAVDFEHHAHLLILGDN
MAB_3756c|M.abscessus_ATCC_199 HKIDYAALVPQAPQNDQPNLRILVGINESELAPTFLEFGEQPHMMIFGDS
Mb3900|M.bovis_AF2122/97 --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5445|M.marinum_M --------------------------------------------------
MLBr_00053|M.leprae_Br4923 --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155 --------------------------------------------------
TH_4195|M.thermoresistible__bu --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 GCGKTAALRTLCRELVRTNTAAQAQLVIVDFRRALLGIVESEQLRGYAMS
MUL_0860|M.ulcerans_Agy99 ACGKSSALRTLCREITRTKTAAQARLFLVDFRRELLGLSESEYLGGHAIA
MAB_3756c|M.abscessus_ATCC_199 ECGKTALLRTMCREIVRTTTPQQAQLFIVDYRRTLLGVVETEHLAKYAMS
Mb3900|M.bovis_AF2122/97 --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5445|M.marinum_M --------------------------------------------------
MLBr_00053|M.leprae_Br4923 --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155 --------------------------------------------------
TH_4195|M.thermoresistible__bu --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 PAALTALLPGLLDLLSGRMPPPDASQAQLRAGSWWSGPDVYVVVDDYDLV
MUL_0860|M.ulcerans_Agy99 AGGLGAFLPGLVELLRARMPAPHLSQARLRDRSWWSGPGIYLMVDDYDLE
MAB_3756c|M.abscessus_ATCC_199 SNTLVDEVPALIELLKSRMPGPDVTQQELRDRSWWSGPEIYILVDDYDLV
Mb3900|M.bovis_AF2122/97 --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5445|M.marinum_M --------------------------------------------------
MLBr_00053|M.leprae_Br4923 --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155 --------------------------------------------------
TH_4195|M.thermoresistible__bu --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 ASPSGNLLAPLVEFLPYASELGLHLIIARRSGGAERAMFEPLLAGLRDLG
MUL_0860|M.ulcerans_Agy99 CTSASNPLLALLEYLPYATDLGLHLIVASRSGGATRALFEPLLAALRDFG
MAB_3756c|M.abscessus_ATCC_199 ALASGNPLLPLAEYLPHSKDIGLHVVIARRTSGASRAMFEPMMARMKDLS
Mb3900|M.bovis_AF2122/97 -------------------------------------------------
Rv3870|M.tuberculosis_H37Rv -------------------------------------------------
MMAR_5445|M.marinum_M -------------------------------------------------
MLBr_00053|M.leprae_Br4923 -------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155 -------------------------------------------------
TH_4195|M.thermoresistible__bu -------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK -------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1 -------------------------------------------------
MAV_4390|M.avium_104 CMSLTMS----EAAPFAAAP--PLPPGRGVLTTRAGADELVQVAWSPP-
MUL_0860|M.ulcerans_Agy99 CMALMMSGRCDEGPLFGSGRPMPLPPGRAVLVTWAGDERLVQVAWTEPG
MAB_3756c|M.abscessus_ATCC_199 CIGLQMSGNKDEGVLLGTVRPSEQPPGRGTLVMRSGGQQLIQVAWSEPQ