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VSRLIFEARRRLAPPSSHQGTIIIEAPPELPRVIPPSLLRRALPYLIGILIVGMIVALVATGMRVISPQT LFFPFVLLLAATALYRGNDKKMRTEEVDAERADYLRYLSVVRDNIRAQAAEQRASALWSHPDPTALASVP GSRRQWERDPHDPDFLVLRAGRHTVPLATTLRVNDTADEIDLEPVSHSALRSLLDTQRSIGDVPTGIDLT KVSPITVLGERAQVRAVLRAWIAQAVTWHDPTVLGVALAARDLEGRDWNWLKWLPHVDIPGRLDALGPAR NLSTDPDELIALLGPVLADRPAFTGQPTDALRHLLIVVDDPDYDLGASPLAVGRAGVTVVHCSASAPHRE QYSDPEKPILRVAHGAIERWQTGGWQPYIDAADQFSADEAAHLARRLSRWDSNPTHAGLRSAATRGASFT TLLGIEDASRLDVPALWAPRRRDEELRVPIGVTGTGEPLMFDLKDEAEGGMGPHGLMIGMTGSGKSQTLM SILLSLLTTHSAERLIVIYADFKGEAGADSFRDFPQVVAVISNMAEKKSLADRFADTLRGEVARREMLLR EAGRKVQGSAFNSVLEYENAIAAGHSLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILF ASQTLDVGKIKDIDKNTAYRIGLKVASPSVSRQIIGVEDAYHIESGKEHKGVGFLVPAPGATPIRFRSTY VDGIYEPPQTAKAVVVQSVPEPKLFTAAAVEPDPGTVIADTDEQEPADPPRKLIATIGEQLARYGPRAPQ LWLPPLDETIPLSAALARAGVGPRQWRWPLGEIDRPFEMRRDPLVFDARSSAGNMVIHGGPKSGKSTALQ TFILSAASLHSPHEVSFYCLDYGGGQLRALQDLAHVGSVASALEPERIRRTFGELEQLLLSRQQREVFRD RGANGSTPDDGFGEVFLVIDNLYGFGRDNTDQFNTRNPLLARVTELVNVGLAYGIHVIITTPSWLEVPLA MRDGLGLRLELRLHDARDSNVRVVGALRRPADAVPHDQPGRGLTMAAEHFLFAAPELDAQTNPVAAINAR YPGMAAPPVRLLPTNLAPHAVGELYRGPDQLVIGQREEDLAPVILDLAANPLLMVFGDARSGKTTLLRHI IRTVREHSTADRVAFTVLDRRLHLVDEPLFPDNEYTANIDRIIPAMLGLANLIEARRPPAGMSAAELSRW TFAGHTHYLIIDDVDQVPDSPAMTGPYIGQRPWTPLIGLLAQAGDLGLRVIVTGRATGSAHLLMTSPLLR RFNDLQATTLMLAGNPADSGKIRGERFARLPAGRAILLTDSDSPTYVQLINPLVDAAAVSGETQQKGSQS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0284 | - | - | 100% (1330) | POSSIBLE CONSERVED MEMBRANE PROTEIN |
M. tuberculosis H37Rv | Rv3447c | - | 0.0 | 34.67% (1318) | hypothetical protein Rv3447c |
M. tuberculosis H37Rv | Rv3894c | - | e-119 | 27.63% (1408) | hypothetical protein Rv3894c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0292 | - | 0.0 | 99.92% (1330) | hypothetical protein Mb0292 |
M. gilvum PYR-GCK | Mflv_0327 | - | 0.0 | 74.38% (1327) | cell divisionFtsK/SpoIIIE |
M. leprae Br4923 | MLBr_02535 | - | 0.0 | 84.14% (1318) | hypothetical protein MLBr_02535 |
M. abscessus ATCC 19977 | MAB_2232c | - | 0.0 | 72.04% (1345) | putative FtsK/SpoIIIE family protein |
M. marinum M | MMAR_0543 | - | 0.0 | 85.56% (1337) | hypothetical protein MMAR_0543 |
M. avium 104 | MAV_4390 | - | 1e-176 | 34.14% (1315) | ftsk/SpoIIIE family protein |
M. smegmatis MC2 155 | MSMEG_0617 | - | 0.0 | 74.66% (1330) | ftsk/SpoIIIE family protein |
M. thermoresistible (build 8) | TH_3306 | - | 0.0 | 76.40% (750) | PUTATIVE cell divisionFtsK/SpoIIIE |
M. ulcerans Agy99 | MUL_1206 | - | 0.0 | 85.34% (1337) | hypothetical protein MUL_1206 |
M. vanbaalenii PYR-1 | Mvan_0413 | - | 0.0 | 74.39% (1343) | cell divisionFtsK/SpoIIIE |
CLUSTAL 2.0.9 multiple sequence alignment Rv0284|M.tuberculosis_H37Rv MSRLIFEARRRLAPPSSHQGTIIIEAPPELPRVIPPSLLRRALPYLIGIL Mb0292|M.bovis_AF2122/97 MSRLIFEARRRLAPPSSHQGTIIIEAPPELPRVIPPSLLRRALPYLIGIL MMAR_0543|M.marinum_M MSRLIFEARRRLAPPNTRKGTITIEAPPELPRVIPPSMLRRAMPVLIVIL MUL_1206|M.ulcerans_Agy99 MSRLIFEARRRLAPPNTRKGTITIEAPPELPRVIPPSMLRRAMPVLIVIL MLBr_02535|M.leprae_Br4923 MSRLIFEARRRLPPPSSRKGTILIEAPSELPRVIPPSLLRRAMPYMIVIL MSMEG_0617|M.smegmatis_MC2_155 MSRLIFEHQRRLTPPTTRKGTITIEPPPQLPRVVPPSLLRRVLPFLIVIL TH_3306|M.thermoresistible__bu MSRLIFETHRRLPPPPVRKGTITIEPPPELPRLVPPSLLRRALPFLIVIL Mflv_0327|M.gilvum_PYR-GCK MSRLIFEHRKRLPAPVARKGTITIEPPPELPRVVPPSLLRRALPYLIVIL Mvan_0413|M.vanbaalenii_PYR-1 MSRLIFEHRKRVPAPVVPKGTITIEPPPELPRVIPPSLLRRALPYLIVIL MAB_2232c|M.abscessus_ATCC_199 MSRLIFEPHRRVAPPAVPDATVTVEAPPQLPRVVPPSFLRRAMPVVIVIL MAV_4390|M.avium_104 ----------------MTQADIVVEAPPELPAPESTGLPARLLPVALSVA .. : :*.*.:** ...: * :* : : Rv0284|M.tuberculosis_H37Rv IVGMIVALVATG-MRVISPQTLFFPFVLLLAATALYRGNDKKMRTEEVDA Mb0292|M.bovis_AF2122/97 IVGMIVALVATG-MRVISPQTLFFPFVLLLAATALYRGNDKKMRTEEVDA MMAR_0543|M.marinum_M IVGMIIALVATG-MKMISPQTLFFPFVLLLAATALFRGNDKKMRTEEVDA MUL_1206|M.ulcerans_Agy99 IVGMIIALVATG-MKMISPQTLFFPFVLLLAATALFRGNDKKMRTEEVDA MLBr_02535|M.leprae_Br4923 IVGMIIAMVATG-MRIISPQTLFFPFVMLLAATALYRGNDNKMSTEEVDA MSMEG_0617|M.smegmatis_MC2_155 IVGMIVALFATG-MRLISPTMLFFPFVLLLAATALYRGGDNKMRTEEVDA TH_3306|M.thermoresistible__bu IVGMIVALVATG-MRLISPQILFFPFVMLLAATALYRGTDNKLRTEEVDA Mflv_0327|M.gilvum_PYR-GCK IVGMIVALVATG-LRLISPTTLFFPFVLLLAATALYRGTDNKMRTEEVDA Mvan_0413|M.vanbaalenii_PYR-1 IVGMIVALVATG-LRMISPTMLFFPFVLLLAATALYRGTDNKMRTEEVDA MAB_2232c|M.abscessus_ATCC_199 IVGMVVALVASG-IRLISPQTLFFPFVLLLAATALYRGGGDKVRTEEVDA MAV_4390|M.avium_104 GIGVMTVVFASGGAAARQPAFLAFPATMLVSTVAAALIGRSRRGGGGLDA :*:: .:.*:* .* * ** .:*:::.* .: :** Rv0284|M.tuberculosis_H37Rv ERADYLRYLSVVRDNIRAQAAEQRASALWSHPDPTALASVPGSRRQWERD Mb0292|M.bovis_AF2122/97 ERADYLRYLSVVRDNIRAQAAEQRASALWSHPDPTALASVPGSRRQWERD MMAR_0543|M.marinum_M ERADYLRYLSVVRDNIRAQAAQQRAAAQWSHPDPDALAAVPGSRRQWERD MUL_1206|M.ulcerans_Agy99 ERADYLRYLSVVRDNIRAQAAQQRAAAQWSHPDPDALAAVPGSRRQWERD MLBr_02535|M.leprae_Br4923 ERADYLRYLSVVRDNIRNQAAEQRAAAQWSHPEPTALAGVPGSRRQWERD MSMEG_0617|M.smegmatis_MC2_155 ERADYLRYLSVVRDNVRAHAAEQRAALEWSHPEPEVLATIPGTRRQWERD TH_3306|M.thermoresistible__bu ERADYLRYLSVVRDNVRAHAAEQRAALEWSHPDPELLANIPGTRRQWERD Mflv_0327|M.gilvum_PYR-GCK ERADYLRYLSVVRDNVRAHADEQRTALQWSHPEPAALNGIPGTRRQWERD Mvan_0413|M.vanbaalenii_PYR-1 ERADYLRYLSVVRDNVRAYADQQRAALQWSHPEPAALVSIPGTRRQWERD MAB_2232c|M.abscessus_ATCC_199 ERADYLRYLSVVRENLRTHAAAQRKALEWSHPDPEELTTVPGSRRQWERD MAV_4390|M.avium_104 DRGRYLEYLNQLGRSVSEIAAAQCASALRDHPDPDTLWTLIGGPRMWRRR :*. **.**. : .: * * : .**:* * : * * *.* Rv0284|M.tuberculosis_H37Rv PHDPDFLVLRAGRHTVPLATTLRVNDTADEIDLEPVSHSALRSLLDTQRS Mb0292|M.bovis_AF2122/97 PHDPDFLVLRAGRHTVPLATTLRVNDTADEIDLEPVSHSALRSLLDTQRS MMAR_0543|M.marinum_M PHDPDFLVLRAGRHSVPLTTTLRVSDTADEIDLEPVSHSALRSLLDTQRT MUL_1206|M.ulcerans_Agy99 PHDPDFLVLRAGRHSVPLTTTLRVSDTADEIDLEPVSHSALRSLLDTQRT MLBr_02535|M.leprae_Br4923 PHDSDFLLVRVGRRQVPLDAALRVKDTADEIDLEPVSYSALRSLLDVHRI MSMEG_0617|M.smegmatis_MC2_155 PRDRDFLVLRAGRHDVPLDAALKVKDTADEIDLEPVAHSALRGLLDVQRT TH_3306|M.thermoresistible__bu PHDADFLVLRAGLHDVPLNTTLRVKDTAEEIDLEPVSHTTLRGLLDVQRT Mflv_0327|M.gilvum_PYR-GCK PHDPDFLVLRAGLHDQPLDVTLRVKDTADEIDLEPVSHTTLRGLLDAQRT Mvan_0413|M.vanbaalenii_PYR-1 PHDPDFLVLRAGLHDQPLATALRVKDTADEIDLEPVSHSTLRSLLDTQRT MAB_2232c|M.abscessus_ATCC_199 PGDDDYLVVRAGRHDVPLASPVRVKDIADEIDLEPVSHSALRGLLDTQRT MAV_4390|M.avium_104 PTGPDFCVVRVGMGVLPLARRVVAPPVPAEEVRDPVTATALRRFLHTHAT * . *: ::*.* ** : . . * :**: ::** :*..: Rv0284|M.tuberculosis_H37Rv IGDVPTGIDLTKVSPITVLGER----AQVRAVLRAWIAQAVTWHDPTVLG Mb0292|M.bovis_AF2122/97 IGDVPTGIDLTKVSRITVLGER----AQVRAVLRAWIAQAVTWHDPTVLG MMAR_0543|M.marinum_M VRDVPTGIDLTKVSRVTLVGDR----AQVRDALRAWVAQAVTWHDPTVLG MUL_1206|M.ulcerans_Agy99 VRDVPTGIDLTKVSRVTLVGDR----AQVRDALRAWVAQAVTWHDPTVLG MLBr_02535|M.leprae_Br4923 VRDVPTGIDLSKVSRITVFIDTESSKDEARAALRAWIAQAVTWHDPALLG MSMEG_0617|M.smegmatis_MC2_155 VRDAPTGLDVAKLARITVIGEA----DEARAAIRAWIAQAVTWHDPTMLG TH_3306|M.thermoresistible__bu VRAAPTGIDVGKMARITVCGDA----DDVRGVVRAWLAQAATWHDPAVLG Mflv_0327|M.gilvum_PYR-GCK LYDVPAGIALTRVSRITVLGDD----AEVTGALRAWVAQAMTWHDPSVLG Mvan_0413|M.vanbaalenii_PYR-1 IHDAPAGVDLTKVARITVIGDR----AEVAGALRAWIAQAVTWHDPSVLG MAB_2232c|M.abscessus_ATCC_199 VRSAPLGIDLNKVSRITVFGDD----DIARAAIRSWVAQAVTFHDPTLLT MAV_4390|M.avium_104 VP-GPVTVDLGAGSPVTIDGDAG----AARAVLRAVVCQLAVLHAPDRVG : * : : : :*: : . .:*: :.* . * * : Rv0284|M.tuberculosis_H37Rv VALAARDLEGRDWNWLKWLPHVDIPGRLDALGPARNLSTDPDELIALLGP Mb0292|M.bovis_AF2122/97 VALAARDLEGRDWNWLKWLPHVDIPGRLDALGPARNLSTDPDELIALLGP MMAR_0543|M.marinum_M VALATRDLESGQWSWLKWLPHVDIPGQADGVGPARYLAADPDDLVEMLAP MUL_1206|M.ulcerans_Agy99 VALATRDLESGLWSWLKWLPHVDIPGQADGVGPARYLAADPDDLVEMLAP MLBr_02535|M.leprae_Br4923 VALATRDLESSDWSWLKWLPHVDIPGQLDGVGSARYLSTDPDELVSLLGA MSMEG_0617|M.smegmatis_MC2_155 VALAAPDLESGDWSWLKWLPHVDVPNEADGVGPARYLTTSTAELRERLAP TH_3306|M.thermoresistible__bu IALAAPDVEGDDWSWLKWLPHTDIPGEIDGVGPARYLATNTAELGRLLAP Mflv_0327|M.gilvum_PYR-GCK IAFAGEALESEAWSWLKWLPHVDVPGRIDGVGPARYLAGDASDLRTLLAP Mvan_0413|M.vanbaalenii_PYR-1 VAFAGTRLESDAWSWLKWLPHTDVPGQNDGVGPARYLATEPAALHALLAP MAB_2232c|M.abscessus_ATCC_199 VAMAGPGVEDAEWSWLKWLPHVDISGEVDGVGPARYLRRTGAELFEALTP MAV_4390|M.avium_104 IAAVVGDGDRAHWDWLKWLPHNRHPTHDDALGPMRMVYSTAAQAQQALAG :* . : *.******* . . *.:*. * : * Rv0284|M.tuberculosis_H37Rv VLADRPAFTGQPTDALRHLLIVVDDPDYDLG---ASPLAVGRAGVTVVHC Mb0292|M.bovis_AF2122/97 VLADRPAFTGQPTDALRHLLIVVDDPDYDLG---ASPLAVGRAGVTVVHC MMAR_0543|M.marinum_M AILDRPAYAGSAADALRHLLIVVDDPDYDIN---ASMLAMGRAGVTVVHC MUL_1206|M.ulcerans_Agy99 AILDRPAYAGSAADALRHLLIVVDDPDYDIN---ASMLAMGRAGVTVVHC MLBr_02535|M.leprae_Br4923 ALTDRPAFTGMSVDALRHLMIVIDEPDYDLN---ASTLVMGRAGVTVVHC MSMEG_0617|M.smegmatis_MC2_155 ALADRPLFPAESGAALKHLLVVLDDPDADPD---DIARKPGLTGVTVIHR TH_3306|M.thermoresistible__bu ALDGRPAFGADT-APVRHLLVVLDDPEADPS---RLVGKAGLAGVTVVHR Mflv_0327|M.gilvum_PYR-GCK ALADRSGFTGDATGTTKHLLIVLDDPDADPS---EFIG-SGLAGVTVIHR Mvan_0413|M.vanbaalenii_PYR-1 ALAERAPFTGDGPTDAKHLLVVLDDPDADPG---QFIG-RGLAGVTVIHR MAB_2232c|M.abscessus_ATCC_199 VLTERELFGADS-GAHKHLLIILDDPAYDLNGVNSPIPATGLDGVTVIQR MAV_4390|M.avium_104 LPVARLVLVAERAVAPIAGATVIAIGAGDDG-----------APVTIRTA * . :: * . **: Rv0284|M.tuberculosis_H37Rv SA---SAPHREQYSDPEKPILRVA----HGAIERWQTGG-WQPYIDAADQ Mb0292|M.bovis_AF2122/97 SA---SAPHREQYSDPEKPILRVA----HGAIERWQTGG-WQPYIDAADQ MMAR_0543|M.marinum_M SS---TLPHREQYSDPEKPILRIE----DGAITRWQTGGGWQAYIDHADQ MUL_1206|M.ulcerans_Agy99 SS---TLPHREQYSDPEKPILRIE----DGAITRWQTGGGWQAYIDHADQ MLBr_02535|M.leprae_Br4923 ST---TPPHREQYSDPDQPILRIV----RGTIERWQTGG-WQPYIDTADR MSMEG_0617|M.smegmatis_MC2_155 TT---ELPNREQYPDPERPILRVA----DGRIERWQVGG-WQPCVDVADA TH_3306|M.thermoresistible__bu SS---AEPHREQYPDPERPILRVV----DGRLERWQSDG-WQPFVDAADR Mflv_0327|M.gilvum_PYR-GCK SA---TEPDRDQYSDPERPVLRIS----GGRIERWQNGT-WASNIDSADH Mvan_0413|M.vanbaalenii_PYR-1 TD---REPDRDQYPDPERPVLRVA----ARRIERWLNGS-WVPFVDAADR MAB_2232c|M.abscessus_ATCC_199 LDGADGTTKLPDYLNPERPVLQVNRNGVSARIARWNGND-WQPYIDEADQ MAV_4390|M.avium_104 AG---------------------------------------TVSPSRPDR . .* Rv0284|M.tuberculosis_H37Rv FSADEAAHLARRLSRWDSNPTHAGLRSAATRGASFTTLLGIEDASRLDVP Mb0292|M.bovis_AF2122/97 FSADEAAHLARRLSRWDSNPTHAGLRSAATRGASFTTLLGIEDASRLDVP MMAR_0543|M.marinum_M LGADEASHLARRLSRWDSNPTHAGLRSAATRGASFTTLLGIPDASQLDVQ MUL_1206|M.ulcerans_Agy99 LGADEASHLARRLSRWDSNPTHAGLRSAATRGASFTTLLGIPDASQLDVQ MLBr_02535|M.leprae_Br4923 LGAHEAAHLARQLSRWDSNPTHAGLRSAATRGASFTTLLGIPDASRLDVT MSMEG_0617|M.smegmatis_MC2_155 MSAAEAAHIARRLSRWDSNPGYI--RSTSTGSATFTTLLGIPDASALDVA TH_3306|M.thermoresistible__bu LSAAECRHLARRLARWDSNPMHA--RSTTTGGATFTTLLGIPDASALDVA Mflv_0327|M.gilvum_PYR-GCK LGAADARHIARRLARWDSNPDHA--RSATTGGAAFTTLLGIPDASALDVA Mvan_0413|M.vanbaalenii_PYR-1 MAPDDARHIARRLARWDSNPHHG--RSASAGGAAFTTLLGIPDASALDVA MAB_2232c|M.abscessus_ATCC_199 LTIGTASHVARRLSRWDSNPTHPGLRSAATGGATFTSLLGIEDASQLDVP MAV_4390|M.avium_104 MTAADALTCARRLAGQR--------VTAGDGDGGWPGLVGLADVSGFDPA : . **:*: :: .. :. *:*: *.* :* Rv0284|M.tuberculosis_H37Rv ALWAPRRRDEELRVPIGVTGTGEPLMFDLKDEAEGGMGPHGLMIGMTGSG Mb0292|M.bovis_AF2122/97 ALWAPRRRDEELRVPIGVTGTGEPLMFDLKDEAEGGMGPHGLMIGMTGSG MMAR_0543|M.marinum_M AIWGQRRRDDELRVPIGITASGEPLMFDLKDEAEGGMGPHGLMIGMTGSG MUL_1206|M.ulcerans_Agy99 AIWGQRRRDDELRVPIGITAGGEPLMFDLKDEAEGGMGPHGLMIGMTGSG MLBr_02535|M.leprae_Br4923 TLWAPRRRDDELRIPIGVTGTGEPLMFDLKDEAEGGMGPHGLMIGMTGSG MSMEG_0617|M.smegmatis_MC2_155 SLWAPRPRDEELRVPIGVTSTGEPLYFDLKDEAEGGMGPHGLMIGMTGSG TH_3306|M.thermoresistible__bu SLWAPRPREEELRVPIGVTATGEPLIFDLKDEAEGGMGPHGLMIGMTGSG Mflv_0327|M.gilvum_PYR-GCK ALWAPRNRDDELRVPIGVTATGEPLIFDLKDEAEGGMGPHGLMIGMTGSG Mvan_0413|M.vanbaalenii_PYR-1 ALWAPRNRDDELRVPIGVTATGEPLIFDLKDEAEGGMGPHGLMIGMTGSG MAB_2232c|M.abscessus_ATCC_199 ALWSPRSRDEELRVPIGVTSSGEPLMFDLKDEAEGGMGPHGLMIGMTGSG MAV_4390|M.avium_104 TLWGRQTGRDRLRAPLGVAADGTPVELDIKEPAEHGMGPHGLCVGATGSG ::*. : :.** *:*::. * *: :*:*: ** ******* :* **** Rv0284|M.tuberculosis_H37Rv KSQTLMSILLSLLTTHSAERLIVIYADFKGEAGADSFRDFPQVVAVISNM Mb0292|M.bovis_AF2122/97 KSQTLMSILLSLLTTHSAERLIVIYADFKGEAGADSFRDFPQVVAVISNM MMAR_0543|M.marinum_M KSQTLMSILLSLLTTHSAERLIVIYADFKGEAGADSFRNFPQVVAVISNM MUL_1206|M.ulcerans_Agy99 KSQTLMSILLSLLTTHSAERLIVIYADFKGEAGADSFRNFPQVVAVISNM MLBr_02535|M.leprae_Br4923 KSQTLMSILLSLLTTHSADRLIVIYADFKGEAGADSFRNFPQVVAVISNM MSMEG_0617|M.smegmatis_MC2_155 KSQTLMSILLSLLTTHPADRLIVIYADFKGEAGADIFRHFPQVVAVISNM TH_3306|M.thermoresistible__bu KSQTLMSILLSLLTTHPADRLIVIYADFKGEAGADIFRNFPQVVAVISNM Mflv_0327|M.gilvum_PYR-GCK KSQTLMSILLSLLTTHPADRLIVIYADFKGEAGADIFRNFPQVVAVISNM Mvan_0413|M.vanbaalenii_PYR-1 KSQTLMAILLSLLTTHPADRLIVIYADFKGEAGADIFRNFPQVVAVISNM MAB_2232c|M.abscessus_ATCC_199 KSQTLMSILLSLLATHSADRLIVIYADFKGEAGADIFRDFPQVVAVISNM MAV_4390|M.avium_104 KSELLRTIALGMMARNSPDVLNLLLVDFKGGATFLDYANAPHVAAVITNL **: * :* *.::: :..: * :: .**** * : . *:*.***:*: Rv0284|M.tuberculosis_H37Rv AEKKSLADRFADTLRGEVARREMLLREAGRKVQGSAFNSVLEYENAIA-- Mb0292|M.bovis_AF2122/97 AEKKSLADRFADTLRGEVARREMLLREAGRKVQGSAFNSVLEYENAIA-- MMAR_0543|M.marinum_M AEKKSLADRFADTLRGEVARRETLLREAGRKIQGSAFNSVLEYENARESA MUL_1206|M.ulcerans_Agy99 AEKKSLADRFADTLRGEVARRETLLREAGRKIQGSAFNSVLEYENARESA MLBr_02535|M.leprae_Br4923 AEKKSLAERFADTLRGEVARRETLLREAGRRVQGSAFNSVLEYENAIAAG MSMEG_0617|M.smegmatis_MC2_155 AEKRSLADRFADTLRGEVARREQILKEAGRRVQGSAFNSVAEYESAIA-- TH_3306|M.thermoresistible__bu AEKRSLAERFADTLRGEVARREQLLREAGRKVQGSAFNSVTEYEEAIE-- Mflv_0327|M.gilvum_PYR-GCK AEKRSLADRFADTLRGEVARREQLLKDSGRRVQGSAFNSVTEYENAVR-- Mvan_0413|M.vanbaalenii_PYR-1 AEKRSLADRFADTLRGEVARREQLLLEAGRRIQNSAFNSVTEYENAIA-- MAB_2232c|M.abscessus_ATCC_199 AEKRSLADRFADTLRGEVARRENLLKQAGRDVQGSAFNSVREYEEAIA-- MAV_4390|M.avium_104 ADDAPLVARMRAALAGEMNRRQEALRTAG-------CDSVAAYQHARR-- *:. .*. *: :* **: **: * :* :** *: * Rv0284|M.tuberculosis_H37Rv --AGHSLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILF Mb0292|M.bovis_AF2122/97 --AGHSLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILF MMAR_0543|M.marinum_M GVAGLDLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILF MUL_1206|M.ulcerans_Agy99 GVAGLDLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILF MLBr_02535|M.leprae_Br4923 ---AVDLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILF MSMEG_0617|M.smegmatis_MC2_155 --AGHDLPPMPTLFVVADEFTLMLAEHPEYADLFDYVARKGRSFRIHLLF TH_3306|M.thermoresistible__bu --AGHDLPPLPTLFVVADEFTLMLADYPEYADLFDYVARKGRSFRIHLLF Mflv_0327|M.gilvum_PYR-GCK --EGHDLPPIPTLLVVADEFTLMLADHPEYADLFDYVARKGRSFRIHLLF Mvan_0413|M.vanbaalenii_PYR-1 --EGHDLPPLPTLFVVADEFTLMLAEHPEYADLFDYVARKGRSFRIHLLF MAB_2232c|M.abscessus_ATCC_199 --AGHDLPPIPTLFVVADEFTLMLQDHPEYAELFDYVARKGRSFRIHILF MAV_4390|M.avium_104 --SAAALPALPTLFVIVDEFSELLSQQPDFADTFVAIGRLGRSLGIHLLL . **.:***:*:.***: :* : *::*: * :.* ***: **:*: Rv0284|M.tuberculosis_H37Rv ASQTLDVGKIKDIDKNTAYRIGLKVASPSVSRQIIGVEDAYHIESGKEHK Mb0292|M.bovis_AF2122/97 ASQTLDVGKIKDIDKNTAYRIGLKVASPSVSRQIIGVEDAYHIESGKEHK MMAR_0543|M.marinum_M ASQTLDVGKIKDIDKNTSYRIGLKVASASVSRQIIGVEDAYHIEAGKEHK MUL_1206|M.ulcerans_Agy99 ASQTLDVGKIKDIDKNTSYRIGLKVASASVSRQIIGVEDAYHIEAGKEHK MLBr_02535|M.leprae_Br4923 ASQTLDFGKIKDIDKNTSYRIGLKVANASVSRQIIGVEDAYHIESGKEHK MSMEG_0617|M.smegmatis_MC2_155 ASQTLDVGRIKDIDKNTSYRIGLKVASPSISRQIIGVEDAYHIESGREHK TH_3306|M.thermoresistible__bu ASQTLDVGRIKDIDKNTSYRIGLKVASPSISRQIIGVEDAYHIESGREHK Mflv_0327|M.gilvum_PYR-GCK ASQTLDVGRIKDIDKNTSYRIGLKVASPSVSRQIIGVEDAYHIESGREHK Mvan_0413|M.vanbaalenii_PYR-1 ASQTLDVGRIKDIDKNTSYRIGLKVASPAVSRQIIGVEDAYHIESGREHK MAB_2232c|M.abscessus_ATCC_199 ASQTLDVGKIKDIDKNTSYRIGLKVASPSASRQIIGTEDAYHIESGKDHK MAV_4390|M.avium_104 ASQRLDEGRLRGLDAHLSYRLCLKTLSEAESRAVLGNLDAYHLPTDP--- *** ** *:::.:* : :**: **. . : ** ::* ****: :. Rv0284|M.tuberculosis_H37Rv GVGFLVPAPGATPIRFRSTYVDGIYEPPQTAKAVVVQSVPEPKLFTAAAV Mb0292|M.bovis_AF2122/97 GVGFLVPAPGATPIRFRSTYVDGIYEPPQTAKAVVVQSVPEPKLFTAAAV MMAR_0543|M.marinum_M GVGFLVPAPGAAPIRFRSTYVDGIYEPPQQTKTRVVHNIPEPKLFTATAV MUL_1206|M.ulcerans_Agy99 GVGFLVPAPGAAPIRFRSTYVDGIYEPPQQTKTRVVHNIPEPKLFTATAV MLBr_02535|M.leprae_Br4923 GMGFLVPSPGAAPIKFRSTYVDGIYEPPRSTKVRVVEVTPEPKLFTAGVV MSMEG_0617|M.smegmatis_MC2_155 GEGFLVPAPGAVPIKFRSTYVDGIYDPPRAEKSIVVHALPQPQVFTAGRV TH_3306|M.thermoresistible__bu GVGFLVPAPGAVPIKFRSTYVDGIYEPPVREKAIAVHADPRPKLFSATRV Mflv_0327|M.gilvum_PYR-GCK GVGFLVPAPGALPVKFRSTYVDGIYEPPRVDRSIVVHAIPKPQLFSAGWV Mvan_0413|M.vanbaalenii_PYR-1 GEGFLVPAPGALPIKFRSTYVDGIYEPPRVDRSIVVHAIPKPQLFSAGWV MAB_2232c|M.abscessus_ATCC_199 GVGFLVPAPGAVPIKFRSTYVDGIYEPPSTTTTVEIRATPQPKQFTALPV MAV_4390|M.avium_104 GAGYLRVG-AGAPIRFQAALVSGPLRPDTAPRPPAMVRVFGTRVVGPVSR * *:* . .. *::*::: *.* * : .: . . Rv0284|M.tuberculosis_H37Rv EPDPGTVIADTDEQEPADPPRKLIATIGEQLARYGPRAPQLWLPPLDETI Mb0292|M.bovis_AF2122/97 EPDPGTVIADTDEQEPADPPRKLIATIGEQLARYGPRAPQLWLPPLDETI MMAR_0543|M.marinum_M EPDPDTVISEVEEEHPVGPPRKLIATIGEQLARYGPQAPRLWLPPLDEPI MUL_1206|M.ulcerans_Agy99 EPDPDTVISEVEEEHPVGPPRKLIATIGEQLARYGPQAPRLWLPPLDEPI MLBr_02535|M.leprae_Br4923 EPDHPIVISSEDEDESVAPPRKLIATIGEQLARYEPRAPKLWLPPLDESI MSMEG_0617|M.smegmatis_MC2_155 EPEPDTVIATGDVEVHTAPPRKLIATIGDQLAAYGPKAPQLWLPPLDEPI TH_3306|M.thermoresistible__bu EPDPGTVVEVAE-------------------------------------- Mflv_0327|M.gilvum_PYR-GCK DPEPDTVIVDDGADVEVLPPRKLIATIGEQLVHYGPRAPQLWLPPLEEAI Mvan_0413|M.vanbaalenii_PYR-1 DPEPDTVIVDDGADVEVLPPRKLITTIGEQLAQYGPRAPQLWLPPLDEPI MAB_2232c|M.abscessus_ATCC_199 AADPTTVIVKGGSDRPAQPARKLISTVGDQLAKVGPRAPQLWLPPLDTAI MAV_4390|M.avium_104 PVEAAHPS-----------GRSISAAVLDRLAGHGPAAHRVWLPPLGRPP : Rv0284|M.tuberculosis_H37Rv PLSAALARAGVGPRQWRWPLGEIDRPFEMRRDPLVFDARSSAGNMVIHGG Mb0292|M.bovis_AF2122/97 PLSAALARAGVGPRQWRWPLGEIDRPFEMRRDPLVFDARSSAGNMVIHGG MMAR_0543|M.marinum_M PLSTLLATAGVAQRQWRWPLGEIDKPFEMRRDPLVFDATSSAGNLVIHGG MUL_1206|M.ulcerans_Agy99 PLSTLLATAGVAQRQWRWPLGEIDKPFEMRRDPLVFDATSSAGNLVIHGG MLBr_02535|M.leprae_Br4923 QLTAILASAEVPQRQWRWPLGEIDKPFEMRRDLLMFDANSSAGNMVIHGG MSMEG_0617|M.smegmatis_MC2_155 ALADVLAGADVEPGQLRWPLGEIDKPFEMRRDVLVYDAHTAAANVLIHGG TH_3306|M.thermoresistible__bu -----------PPGXX-------------------------------XGG Mflv_0327|M.gilvum_PYR-GCK PLQGLLERSGIGAGQWRWPLGEIDRPFDMRRDPLVFDATSAAANMVIHGG Mvan_0413|M.vanbaalenii_PYR-1 PLRDVLERAGVGARQWRWPLGEIDRPFEMRRDPLIFDATSAAANMVIHGG MAB_2232c|M.abscessus_ATCC_199 PLASVLDETGLPARQLRWPLGEIDKPFQMRRDPLIFDATSAAGNVIIHGG MAV_4390|M.avium_104 ELRTLLG----GAADLTVPVGLVDRPFEQCRTPLIVDLSGAAGNVAVVGA *. Rv0284|M.tuberculosis_H37Rv PKSGKSTALQTFILSAASLHSPHEVSFYCLDYGGGQLRALQDLAHVGSVA Mb0292|M.bovis_AF2122/97 PKSGKSTALQTFILSAASLHSPHEVSFYCLDYGGGQLRALQDLAHVGSVA MMAR_0543|M.marinum_M PKSGKSTALQSFMLSAASLHSPSEVTFYCLDYGGGQLRALQDLAHVGSVA MUL_1206|M.ulcerans_Agy99 PKSGKSTALQSFMLSAASLHSPSEVTFYCLDYGG-QLRALQDLAHVGSVA MLBr_02535|M.leprae_Br4923 PKSGKSTALQTFILSAASLHSPRDVTFYCLDYGGGQLRAIQDLLHIGSVA MSMEG_0617|M.smegmatis_MC2_155 PRSGKSTALQAFVLSAAALHSPRAITFYCLDYGGGKLADLADLAHVGSVA TH_3306|M.thermoresistible__bu GRNDR-----------------------RRDRGG---------------- Mflv_0327|M.gilvum_PYR-GCK PKSGKSTALQTFVLSAAALHAPGDVSFYCLDYGGGQLRVLDGLAHVGSVA Mvan_0413|M.vanbaalenii_PYR-1 PKSGKSSALQTFVLSAAALHAPGDVSFYCLDYGGGQLRALENLAHVGSVA MAB_2232c|M.abscessus_ATCC_199 PKSGKSTALQTFMLSAAALHSPRDVTFYCIDYGGGQLHALDGLAHVGSVA MAV_4390|M.avium_104 PRSGKSTALRTLITALAATHDPARVQFYCLDFGGGALSSLHTLPHVGAVA :..: * ** Rv0284|M.tuberculosis_H37Rv SALEPERIRRTFGELEQLLLSRQ-----QREVFRDRGANG----STPDDG Mb0292|M.bovis_AF2122/97 SALEPERIRRTFGELEQLLLSRQ-----QREVFRDRGANG----STPDDG MMAR_0543|M.marinum_M SALEPERIRRTFGELEQLLLARQ-----QREVFRDRGGNGQAHGSVPDDG MUL_1206|M.ulcerans_Agy99 SALEPERIRRTFGELEQLLLARQ-----QREVFRDRGGNGQVHGSVPDDG MLBr_02535|M.leprae_Br4923 SALEPERIRRTFGELEQLLLSRQ-----QREVFRDKRASG----SAPDDC MSMEG_0617|M.smegmatis_MC2_155 TPLEPERIRRTFGELEQLLRARQ-----RQGAVNRT--------GSYTDG TH_3306|M.thermoresistible__bu ---------RRFGAADHHHHDQD-----DQEHHQRH--------RRRGD- Mflv_0327|M.gilvum_PYR-GCK SPLESERIRRTFGELEQLLQARQ-----RHGAAVNN--------GGYRDG Mvan_0413|M.vanbaalenii_PYR-1 SPLEPERIRRTFGELEHLLRARQ-----QHGAAAAD--------GQYRDG MAB_2232c|M.abscessus_ATCC_199 SALEPERIRRTFGELEQLLAYRQRLFRDRGIASVSQLRALRDSDRTLDDG MAV_4390|M.avium_104 GRAEPRRVGRIVAECEAVVGRREAFFGEHAIASIADYRQR----RPGSDP * .. : :: * Rv0284|M.tuberculosis_H37Rv FGEVFLVIDNLYGFGRDNTDQFNTRNPLLARVTELVNVGLAYGIHVIITT Mb0292|M.bovis_AF2122/97 FGEVFLVIDNLYGFGRDNTDQFNTRNPLLARVTELVNVGLAYGIHVIITT MMAR_0543|M.marinum_M FGEVFLVIDNLYAFSRDNTDQFNTRNPLLARVTELVNVGMAYGIHVIITT MUL_1206|M.ulcerans_Agy99 FGEVFLVIDNLYAFSRDNTDQFNTRNPLLARVTELVNVGMAYGIHVIITT MLBr_02535|M.leprae_Br4923 FGDVFLVIDNLYAFGRDNTDQFNTRNPLLAKVTELVNVGLAYGIHVIITT MSMEG_0617|M.smegmatis_MC2_155 YGEVFLVIDNLYAFSRDNTDTFNTRNPLLAKVTELANSGLAYGIHVVITT TH_3306|M.thermoresistible__bu --------------HREYAAPFTS-------------------------- Mflv_0327|M.gilvum_PYR-GCK YGEVFLLIDNLYAFSRDNTDTFNTRNPLLAKVTELVNTGLAYGIHVVITT Mvan_0413|M.vanbaalenii_PYR-1 YGEVFLLIDNLYAFSRDNTDTFNARNPLLARVTELVNTGLSYGIHVVVTT MAB_2232c|M.abscessus_ATCC_199 YGETFLIVDNLYAFSRDNTDQFNTRNPLLARLTELANAGLSYGIHVVITT MAV_4390|M.avium_104 FGDVFLVIDGWAVLRRDFET-------LEASIIALAGQGLSFGVHLVLSA *: Rv0284|M.tuberculosis_H37Rv PSWLEVPLAMRDGLGLRLELRLHDARDSNVRVVG---ALRRPADAVPHDQ Mb0292|M.bovis_AF2122/97 PSWLEVPLAMRDGLGLRLELRLHDARDSNVRVVG---ALRRPADAVPHDQ MMAR_0543|M.marinum_M PSWLEVPLAMRDGLGMRLELRLHDARDSNVRVVG---ALRRPAESVPHDQ MUL_1206|M.ulcerans_Agy99 PSWLEVPLAMRDGLGMRLELRLHDARDSNVRVVG---ALRRPAESVPHDH MLBr_02535|M.leprae_Br4923 SSWLEVPLVMRDGFGLRLELKLPDARDSNVRVVG---ALRRPADAVPHDQ MSMEG_0617|M.smegmatis_MC2_155 PNWLEVPLAMRDGLGLRLELKLHDSHDSIVRVAG---ALRRPADSVPADQ TH_3306|M.thermoresistible__bu -------------------------------------------------- Mflv_0327|M.gilvum_PYR-GCK PNWLEVPLAMRDGLGLRLELRLHDAHDSNVRVVG---ALRRPAEGVPADQ Mvan_0413|M.vanbaalenii_PYR-1 PNWLEVPLTMRDGLGLRLELRLHDPRDSNVRVVSKDAALRRPAESVPADQ MAB_2232c|M.abscessus_ATCC_199 PNWIEVPLAMRDSLGLRLELKLHDSADSNVRVPG---ALRRPAESVPHDQ MAV_4390|M.avium_104 SRWADIRPALRDQIGTRIELRLGDPADSEID--------RRAAAHVPRDS Rv0284|M.tuberculosis_H37Rv PGRGLTMAAEHFLFAAPELDAQTNPVAAINARYPGMAAPPVRLLPTNLAP Mb0292|M.bovis_AF2122/97 PGRGLTMAAEHFLFAAPELDAQTNPVAAINARYPGMAAPPVRLLPTNLAP MMAR_0543|M.marinum_M PGRGLTMAAEHFLFAAPELDQVP----AINARYPGMAAPPVRLLPIDLAP MUL_1206|M.ulcerans_Agy99 PGRGLTMAAEHFLFAAPELDQVP----AINARYPGMAAPPVRLLPIDLAP MLBr_02535|M.leprae_Br4923 PGRGLTMAAEHFLFAAPQLDQVA----VINARHAGVAAPPVRLLPANLAP MSMEG_0617|M.smegmatis_MC2_155 PGRGLTMAAEHFLFAEPALSDIA----VINARYPGVSAPPVRLLPTDLSP TH_3306|M.thermoresistible__bu -------------------------------------------------- Mflv_0327|M.gilvum_PYR-GCK PGRGLTMAAEHFLFARPAPETIP----ALNARFPGQSAPEVRLLPTRLSP Mvan_0413|M.vanbaalenii_PYR-1 PGRGLTMAVEHFLFAAPATESIP----ALNARYPGRSAPPVRLLPTDLSP MAB_2232c|M.abscessus_ATCC_199 PGRGLTMQAEHFLFAASDAKTVD----SVNANYPGAKAPAVRLLPADLAP MAV_4390|M.avium_104 PGRGLSHDGLHMVIASPVADVAAG----------ESVAPPIPLLPARVDL Rv0284|M.tuberculosis_H37Rv HAV--GELYRGPDQLVIGQREEDLAPVILDLAANPLLMVFGDARSGKTTL Mb0292|M.bovis_AF2122/97 HAV--GELYRGPDQLVIGQREEDLAPVILDLAANPLLMVFGDARSGKTTL MMAR_0543|M.marinum_M DAV--GNLYRGPDQIVIGQREEDLAPVVLNLAENPLLMVFGDSKSGKTTL MUL_1206|M.ulcerans_Agy99 DAV--GNLYRGPDQIVIGQREEDLAPVVLNLAENPLLMVFGDSKSGKTTL MLBr_02535|M.leprae_Br4923 DAV--GALYRGPEQVVIGQREEDLAPVVVDFANNPLLMVFGDSKSGKTTL MSMEG_0617|M.smegmatis_MC2_155 DAL--APLYPAPETVVIGQREEDLAPVAVDFANHPLLMVFGDSKSGKTTL TH_3306|M.thermoresistible__bu --------------AVLGHRR------------------------SRSSP Mflv_0327|M.gilvum_PYR-GCK RAF--ASLYPAPERVVIGQREEDLAAVSVDFADNPLLMVFGDTKTGKTTL Mvan_0413|M.vanbaalenii_PYR-1 SAF--PTLYPAPERVVVGQREEDLAAVTVDFGDNPLMMVFGDAKTGKTTL MAB_2232c|M.abscessus_ATCC_199 GAI--GPLYPGREQVVIGQREQDLAPVALDFSHNPLLMVLGDTGSGKTTL MAV_4390|M.avium_104 DAVRRGSGDEFAGRPLLGLQERQLQPLAIDFARESHLLILGANGCGKTAA ::* :. .::: Rv0284|M.tuberculosis_H37Rv LRHIIRTVREHSTADRVAFTVLDRRLHLVDEPLFPDNE-YTANIDRIIPA Mb0292|M.bovis_AF2122/97 LRHIIRTVREHSTADRVAFTVLDRRLHLVDEPLFPDNE-YTANIDRIIPA MMAR_0543|M.marinum_M LRHIIRTVREHSTEDQVAFTVLDRRLHLVDEPLFPENE-YTANIDRIVPA MUL_1206|M.ulcerans_Agy99 LRHIIRTVREHSTEDQVAFTVLDRRLHLVDEPLFPENE-YTANIDRIVPA MLBr_02535|M.leprae_Br4923 LRHIIRTIREHSSPDQVAFIVLDRRLHLVDEPLFPDNE-YTANIDRIIPA MSMEG_0617|M.smegmatis_MC2_155 LRHIIRTVRENSTPDQVAFTVIDRRLHLVDEPLFPDNE-YTANIDRVLPA TH_3306|M.thermoresistible__bu FRYFLGPSRTCATP------------------------------------ Mflv_0327|M.gilvum_PYR-GCK LRHLIRTLRENSRADQVAFTVIDRRLQLVDEPIFPDNE-YTPNIDRILPA Mvan_0413|M.vanbaalenii_PYR-1 LRHLIRTIRENSRPDQVAFTVIDRRLQLVDEPIFPDNE-YTPNIDRITPA MAB_2232c|M.abscessus_ATCC_199 LRHIIRTVREHSTPDQVAFTVLDRRLHLVDEPLFPENE-YTPNIDRITPA MAV_4390|M.avium_104 LRTLCRELVRTNTAAQAQLVIVDFRRALLGIVESEQLRGYAMSPAALTAL :* : Rv0284|M.tuberculosis_H37Rv MLGLANLIEARRPPAGMSAAELSRWTFAG-------HTHYLIIDDVDQVP Mb0292|M.bovis_AF2122/97 MLGLANLIEARRPPAGMSAAELSRWTFAG-------HTHYLIIDDVDQVP MMAR_0543|M.marinum_M MLGLANLIDSRRPPAGMSAAELARWTYQG-------HTHYLIIDDVDQIP MUL_1206|M.ulcerans_Agy99 MLGLANLIDSRRPPTGMSAAELARWTYQG-------HTHYLIIDDVDQIP MLBr_02535|M.leprae_Br4923 MLGLANLIEARRPPVGLSAAELSRWAFAG-------HIHYLLIDDVDQVP MSMEG_0617|M.smegmatis_MC2_155 MLGLSALIEKRRPPAGLSAQELSRWTYTG-------HTHYLIVDDVDQIP TH_3306|M.thermoresistible__bu -------------------------------------------------- Mflv_0327|M.gilvum_PYR-GCK MLGLAGLLEKRRPPAGLSPQELRGWDFRSSANGSGSHLHYLIIDDVDQIP Mvan_0413|M.vanbaalenii_PYR-1 MLGLSALLEKRRPPAGLSPQELSRWDFRAGANGSGRHLHYLIIDDVDQIP MAB_2232c|M.abscessus_ATCC_199 MLGLGALLEKRRPPAGLSPEELHSWVSRG----VTAQRHYLIIDDVDQIP MAV_4390|M.avium_104 LPGLLDLLSGRMPPPDASQAQLRAGSWWS------GPDVYVVVDDYDLVA Rv0284|M.tuberculosis_H37Rv DSPAMTGPYIGQRPWTPLIGLLAQAGDLGLRVIVTGRATGSAHLLMTSPL Mb0292|M.bovis_AF2122/97 DSPAMTGPYIGQRPWTPLIGLLAQAGDLGLRVIVTGRATGSAHLLMTSPL MMAR_0543|M.marinum_M DTAAMSGPFAGQRPWTPLIGLLAQAADLGLRVIVTARASGSAHALMTSPL MUL_1206|M.ulcerans_Agy99 DTAAMSGPFAGQRPWTPLIGLLAQAADLGLRVIVTARASGSAHALMTSPL MLBr_02535|M.leprae_Br4923 DSPAMSGPYIGQRPWTNLIGLLGQAGDLGLRVIVTGRATGSGHALMTNQL MSMEG_0617|M.smegmatis_MC2_155 DTPAVSGPFVGQRPWTNIVGLLAEAADLGLRVIVTARATGSAHAVMTAPL TH_3306|M.thermoresistible__bu ----------APRPRR------------ARRTRVCASRAVRTRSECTRPS Mflv_0327|M.gilvum_PYR-GCK DGPAVSGPYAGQRPWTPVIGLLSQASELGLRVIVTARAAGSAHAVMTAPL Mvan_0413|M.vanbaalenii_PYR-1 DGPAISGPFAGQRPWTALIGLLAQASDLGLRVIVTARAAGSAHAVMTAPL MAB_2232c|M.abscessus_ATCC_199 DAPAVSGPYIGQRPWNPITGLLAEARELGLRVIITARATGSGHILMTNPM MAV_4390|M.avium_104 SP--------SGNLLAPLVEFLPYASELGLHLIIARRSGG-AERAMFEPL . . . : : . Rv0284|M.tuberculosis_H37Rv LRRFNDLQATTLMLAGNPADSGKIRGERFARLPAGRAILLTD---SDSPT Mb0292|M.bovis_AF2122/97 LRRFNDLQATTLMLAGNPADSGKIRGERFARLPAGRAILLTD---SDSPT MMAR_0543|M.marinum_M LRRFNDLQATTLMLAGNPQDSGKIRGQRFSRLPAGRAMLLGD---SDDPT MUL_1206|M.ulcerans_Agy99 LRRFNDLQATTLMLAGNPQDSGKIRGQRFSRLPAGRAMLLGD---SDDPT MLBr_02535|M.leprae_Br4923 LRRLNDLQATTLMLAGNPADSGKIRGQRFSRLPAGRAILLSD---SNSPT MSMEG_0617|M.smegmatis_MC2_155 LRRLNDLQATTLMLSGNPTDSGKIRGHRFARFPAGRGLLLTD---TDTPD TH_3306|M.thermoresistible__bu PR------------------------------------------------ Mflv_0327|M.gilvum_PYR-GCK LRRLNELQATTLLLSGNPQDSGKIRGHRFSRLPAGRGLLLDDSNLSDTPT Mvan_0413|M.vanbaalenii_PYR-1 LRRLNDLQATTFLLSGNPADSGKIRGHRFARLPVGRAMLLDDRNSSGSPT MAB_2232c|M.abscessus_ATCC_199 LRRFHELQANTLMLSGSPQDGGRIRGHRFERLPAGRGILLSD---NDVPT MAV_4390|M.avium_104 LAGLRDLGCMSLTMSEAAPFAAAPP------LPPGRGVLTTR---AGADE Rv0284|M.tuberculosis_H37Rv YVQLINPLVDAAAVSGETQQKGSQS----- Mb0292|M.bovis_AF2122/97 YVQLINPLVDAAAVSGETQQKGSQS----- MMAR_0543|M.marinum_M YVQLVNPLVGEAATVTETQQKGN------- MUL_1206|M.ulcerans_Agy99 YVQLVNPLVGEAATVTETQQKDSY------ MLBr_02535|M.leprae_Br4923 YVQLVNPLAGESVP--ERVNDGGFL----- MSMEG_0617|M.smegmatis_MC2_155 HIQLVNPLGDAALSGNIGNNGNHNRGGEYR TH_3306|M.thermoresistible__bu ------------------------------ Mflv_0327|M.gilvum_PYR-GCK YVQLVDPLADDATAPAGHLGKEYS------ Mvan_0413|M.vanbaalenii_PYR-1 FVQLVNPLAERTAARSGHSGKEYS------ MAB_2232c|M.abscessus_ATCC_199 YVQTVNPLVSEHAAQGREYPR--------- MAV_4390|M.avium_104 LVQVAWSPP---------------------