For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv0284 (-)

annotation: POSSIBLE CONSERVED MEMBRANE PROTEIN
coordinates: 345635 - 349627
length: 1330

VSRLIFEARRRLAPPSSHQGTIIIEAPPELPRVIPPSLLRRALPYLIGILIVGMIVALVATGMRVISPQT
LFFPFVLLLAATALYRGNDKKMRTEEVDAERADYLRYLSVVRDNIRAQAAEQRASALWSHPDPTALASVP
GSRRQWERDPHDPDFLVLRAGRHTVPLATTLRVNDTADEIDLEPVSHSALRSLLDTQRSIGDVPTGIDLT
KVSPITVLGERAQVRAVLRAWIAQAVTWHDPTVLGVALAARDLEGRDWNWLKWLPHVDIPGRLDALGPAR
NLSTDPDELIALLGPVLADRPAFTGQPTDALRHLLIVVDDPDYDLGASPLAVGRAGVTVVHCSASAPHRE
QYSDPEKPILRVAHGAIERWQTGGWQPYIDAADQFSADEAAHLARRLSRWDSNPTHAGLRSAATRGASFT
TLLGIEDASRLDVPALWAPRRRDEELRVPIGVTGTGEPLMFDLKDEAEGGMGPHGLMIGMTGSGKSQTLM
SILLSLLTTHSAERLIVIYADFKGEAGADSFRDFPQVVAVISNMAEKKSLADRFADTLRGEVARREMLLR
EAGRKVQGSAFNSVLEYENAIAAGHSLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILF
ASQTLDVGKIKDIDKNTAYRIGLKVASPSVSRQIIGVEDAYHIESGKEHKGVGFLVPAPGATPIRFRSTY
VDGIYEPPQTAKAVVVQSVPEPKLFTAAAVEPDPGTVIADTDEQEPADPPRKLIATIGEQLARYGPRAPQ
LWLPPLDETIPLSAALARAGVGPRQWRWPLGEIDRPFEMRRDPLVFDARSSAGNMVIHGGPKSGKSTALQ
TFILSAASLHSPHEVSFYCLDYGGGQLRALQDLAHVGSVASALEPERIRRTFGELEQLLLSRQQREVFRD
RGANGSTPDDGFGEVFLVIDNLYGFGRDNTDQFNTRNPLLARVTELVNVGLAYGIHVIITTPSWLEVPLA
MRDGLGLRLELRLHDARDSNVRVVGALRRPADAVPHDQPGRGLTMAAEHFLFAAPELDAQTNPVAAINAR
YPGMAAPPVRLLPTNLAPHAVGELYRGPDQLVIGQREEDLAPVILDLAANPLLMVFGDARSGKTTLLRHI
IRTVREHSTADRVAFTVLDRRLHLVDEPLFPDNEYTANIDRIIPAMLGLANLIEARRPPAGMSAAELSRW
TFAGHTHYLIIDDVDQVPDSPAMTGPYIGQRPWTPLIGLLAQAGDLGLRVIVTGRATGSAHLLMTSPLLR
RFNDLQATTLMLAGNPADSGKIRGERFARLPAGRAILLTDSDSPTYVQLINPLVDAAAVSGETQQKGSQS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0284--100% (1330)POSSIBLE CONSERVED MEMBRANE PROTEIN
M. tuberculosis H37RvRv3447c-0.034.67% (1318) hypothetical protein Rv3447c
M. tuberculosis H37RvRv3894c-e-11927.63% (1408) hypothetical protein Rv3894c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0292-0.099.92% (1330) hypothetical protein Mb0292
M. gilvum PYR-GCKMflv_0327-0.074.38% (1327) cell divisionFtsK/SpoIIIE
M. leprae Br4923MLBr_02535-0.084.14% (1318) hypothetical protein MLBr_02535
M. abscessus ATCC 19977MAB_2232c-0.072.04% (1345) putative FtsK/SpoIIIE family protein
M. marinum MMMAR_0543-0.085.56% (1337) hypothetical protein MMAR_0543
M. avium 104MAV_4390-1e-17634.14% (1315) ftsk/SpoIIIE family protein
M. smegmatis MC2 155MSMEG_0617-0.074.66% (1330) ftsk/SpoIIIE family protein
M. thermoresistible (build 8)TH_3306-0.076.40% (750) PUTATIVE cell divisionFtsK/SpoIIIE
M. ulcerans Agy99MUL_1206-0.085.34% (1337) hypothetical protein MUL_1206
M. vanbaalenii PYR-1Mvan_0413-0.074.39% (1343) cell divisionFtsK/SpoIIIE

CLUSTAL 2.0.9 multiple sequence alignment


Rv0284|M.tuberculosis_H37Rv         MSRLIFEARRRLAPPSSHQGTIIIEAPPELPRVIPPSLLRRALPYLIGIL
Mb0292|M.bovis_AF2122/97            MSRLIFEARRRLAPPSSHQGTIIIEAPPELPRVIPPSLLRRALPYLIGIL
MMAR_0543|M.marinum_M               MSRLIFEARRRLAPPNTRKGTITIEAPPELPRVIPPSMLRRAMPVLIVIL
MUL_1206|M.ulcerans_Agy99           MSRLIFEARRRLAPPNTRKGTITIEAPPELPRVIPPSMLRRAMPVLIVIL
MLBr_02535|M.leprae_Br4923          MSRLIFEARRRLPPPSSRKGTILIEAPSELPRVIPPSLLRRAMPYMIVIL
MSMEG_0617|M.smegmatis_MC2_155      MSRLIFEHQRRLTPPTTRKGTITIEPPPQLPRVVPPSLLRRVLPFLIVIL
TH_3306|M.thermoresistible__bu      MSRLIFETHRRLPPPPVRKGTITIEPPPELPRLVPPSLLRRALPFLIVIL
Mflv_0327|M.gilvum_PYR-GCK          MSRLIFEHRKRLPAPVARKGTITIEPPPELPRVVPPSLLRRALPYLIVIL
Mvan_0413|M.vanbaalenii_PYR-1       MSRLIFEHRKRVPAPVVPKGTITIEPPPELPRVIPPSLLRRALPYLIVIL
MAB_2232c|M.abscessus_ATCC_199      MSRLIFEPHRRVAPPAVPDATVTVEAPPQLPRVVPPSFLRRAMPVVIVIL
MAV_4390|M.avium_104                ----------------MTQADIVVEAPPELPAPESTGLPARLLPVALSVA
                                                      .. : :*.*.:**   ...:  * :*  : : 

Rv0284|M.tuberculosis_H37Rv         IVGMIVALVATG-MRVISPQTLFFPFVLLLAATALYRGNDKKMRTEEVDA
Mb0292|M.bovis_AF2122/97            IVGMIVALVATG-MRVISPQTLFFPFVLLLAATALYRGNDKKMRTEEVDA
MMAR_0543|M.marinum_M               IVGMIIALVATG-MKMISPQTLFFPFVLLLAATALFRGNDKKMRTEEVDA
MUL_1206|M.ulcerans_Agy99           IVGMIIALVATG-MKMISPQTLFFPFVLLLAATALFRGNDKKMRTEEVDA
MLBr_02535|M.leprae_Br4923          IVGMIIAMVATG-MRIISPQTLFFPFVMLLAATALYRGNDNKMSTEEVDA
MSMEG_0617|M.smegmatis_MC2_155      IVGMIVALFATG-MRLISPTMLFFPFVLLLAATALYRGGDNKMRTEEVDA
TH_3306|M.thermoresistible__bu      IVGMIVALVATG-MRLISPQILFFPFVMLLAATALYRGTDNKLRTEEVDA
Mflv_0327|M.gilvum_PYR-GCK          IVGMIVALVATG-LRLISPTTLFFPFVLLLAATALYRGTDNKMRTEEVDA
Mvan_0413|M.vanbaalenii_PYR-1       IVGMIVALVATG-LRMISPTMLFFPFVLLLAATALYRGTDNKMRTEEVDA
MAB_2232c|M.abscessus_ATCC_199      IVGMVVALVASG-IRLISPQTLFFPFVLLLAATALYRGGGDKVRTEEVDA
MAV_4390|M.avium_104                GIGVMTVVFASGGAAARQPAFLAFPATMLVSTVAAALIGRSRRGGGGLDA
                                     :*:: .:.*:*     .*  * ** .:*:::.*      .:     :**

Rv0284|M.tuberculosis_H37Rv         ERADYLRYLSVVRDNIRAQAAEQRASALWSHPDPTALASVPGSRRQWERD
Mb0292|M.bovis_AF2122/97            ERADYLRYLSVVRDNIRAQAAEQRASALWSHPDPTALASVPGSRRQWERD
MMAR_0543|M.marinum_M               ERADYLRYLSVVRDNIRAQAAQQRAAAQWSHPDPDALAAVPGSRRQWERD
MUL_1206|M.ulcerans_Agy99           ERADYLRYLSVVRDNIRAQAAQQRAAAQWSHPDPDALAAVPGSRRQWERD
MLBr_02535|M.leprae_Br4923          ERADYLRYLSVVRDNIRNQAAEQRAAAQWSHPEPTALAGVPGSRRQWERD
MSMEG_0617|M.smegmatis_MC2_155      ERADYLRYLSVVRDNVRAHAAEQRAALEWSHPEPEVLATIPGTRRQWERD
TH_3306|M.thermoresistible__bu      ERADYLRYLSVVRDNVRAHAAEQRAALEWSHPDPELLANIPGTRRQWERD
Mflv_0327|M.gilvum_PYR-GCK          ERADYLRYLSVVRDNVRAHADEQRTALQWSHPEPAALNGIPGTRRQWERD
Mvan_0413|M.vanbaalenii_PYR-1       ERADYLRYLSVVRDNVRAYADQQRAALQWSHPEPAALVSIPGTRRQWERD
MAB_2232c|M.abscessus_ATCC_199      ERADYLRYLSVVRENLRTHAAAQRKALEWSHPDPEELTTVPGSRRQWERD
MAV_4390|M.avium_104                DRGRYLEYLNQLGRSVSEIAAAQCASALRDHPDPDTLWTLIGGPRMWRRR
                                    :*. **.**. :  .:   *  *  :   .**:*  *  : *  * *.* 

Rv0284|M.tuberculosis_H37Rv         PHDPDFLVLRAGRHTVPLATTLRVNDTADEIDLEPVSHSALRSLLDTQRS
Mb0292|M.bovis_AF2122/97            PHDPDFLVLRAGRHTVPLATTLRVNDTADEIDLEPVSHSALRSLLDTQRS
MMAR_0543|M.marinum_M               PHDPDFLVLRAGRHSVPLTTTLRVSDTADEIDLEPVSHSALRSLLDTQRT
MUL_1206|M.ulcerans_Agy99           PHDPDFLVLRAGRHSVPLTTTLRVSDTADEIDLEPVSHSALRSLLDTQRT
MLBr_02535|M.leprae_Br4923          PHDSDFLLVRVGRRQVPLDAALRVKDTADEIDLEPVSYSALRSLLDVHRI
MSMEG_0617|M.smegmatis_MC2_155      PRDRDFLVLRAGRHDVPLDAALKVKDTADEIDLEPVAHSALRGLLDVQRT
TH_3306|M.thermoresistible__bu      PHDADFLVLRAGLHDVPLNTTLRVKDTAEEIDLEPVSHTTLRGLLDVQRT
Mflv_0327|M.gilvum_PYR-GCK          PHDPDFLVLRAGLHDQPLDVTLRVKDTADEIDLEPVSHTTLRGLLDAQRT
Mvan_0413|M.vanbaalenii_PYR-1       PHDPDFLVLRAGLHDQPLATALRVKDTADEIDLEPVSHSTLRSLLDTQRT
MAB_2232c|M.abscessus_ATCC_199      PGDDDYLVVRAGRHDVPLASPVRVKDIADEIDLEPVSHSALRGLLDTQRT
MAV_4390|M.avium_104                PTGPDFCVVRVGMGVLPLARRVVAPPVPAEEVRDPVTATALRRFLHTHAT
                                    * . *: ::*.*    **   : .   . *   :**: ::** :*..:  

Rv0284|M.tuberculosis_H37Rv         IGDVPTGIDLTKVSPITVLGER----AQVRAVLRAWIAQAVTWHDPTVLG
Mb0292|M.bovis_AF2122/97            IGDVPTGIDLTKVSRITVLGER----AQVRAVLRAWIAQAVTWHDPTVLG
MMAR_0543|M.marinum_M               VRDVPTGIDLTKVSRVTLVGDR----AQVRDALRAWVAQAVTWHDPTVLG
MUL_1206|M.ulcerans_Agy99           VRDVPTGIDLTKVSRVTLVGDR----AQVRDALRAWVAQAVTWHDPTVLG
MLBr_02535|M.leprae_Br4923          VRDVPTGIDLSKVSRITVFIDTESSKDEARAALRAWIAQAVTWHDPALLG
MSMEG_0617|M.smegmatis_MC2_155      VRDAPTGLDVAKLARITVIGEA----DEARAAIRAWIAQAVTWHDPTMLG
TH_3306|M.thermoresistible__bu      VRAAPTGIDVGKMARITVCGDA----DDVRGVVRAWLAQAATWHDPAVLG
Mflv_0327|M.gilvum_PYR-GCK          LYDVPAGIALTRVSRITVLGDD----AEVTGALRAWVAQAMTWHDPSVLG
Mvan_0413|M.vanbaalenii_PYR-1       IHDAPAGVDLTKVARITVIGDR----AEVAGALRAWIAQAVTWHDPSVLG
MAB_2232c|M.abscessus_ATCC_199      VRSAPLGIDLNKVSRITVFGDD----DIARAAIRSWVAQAVTFHDPTLLT
MAV_4390|M.avium_104                VP-GPVTVDLGAGSPVTIDGDAG----AARAVLRAVVCQLAVLHAPDRVG
                                    :   *  : :   : :*:  :       .  .:*: :.*  . * *  : 

Rv0284|M.tuberculosis_H37Rv         VALAARDLEGRDWNWLKWLPHVDIPGRLDALGPARNLSTDPDELIALLGP
Mb0292|M.bovis_AF2122/97            VALAARDLEGRDWNWLKWLPHVDIPGRLDALGPARNLSTDPDELIALLGP
MMAR_0543|M.marinum_M               VALATRDLESGQWSWLKWLPHVDIPGQADGVGPARYLAADPDDLVEMLAP
MUL_1206|M.ulcerans_Agy99           VALATRDLESGLWSWLKWLPHVDIPGQADGVGPARYLAADPDDLVEMLAP
MLBr_02535|M.leprae_Br4923          VALATRDLESSDWSWLKWLPHVDIPGQLDGVGSARYLSTDPDELVSLLGA
MSMEG_0617|M.smegmatis_MC2_155      VALAAPDLESGDWSWLKWLPHVDVPNEADGVGPARYLTTSTAELRERLAP
TH_3306|M.thermoresistible__bu      IALAAPDVEGDDWSWLKWLPHTDIPGEIDGVGPARYLATNTAELGRLLAP
Mflv_0327|M.gilvum_PYR-GCK          IAFAGEALESEAWSWLKWLPHVDVPGRIDGVGPARYLAGDASDLRTLLAP
Mvan_0413|M.vanbaalenii_PYR-1       VAFAGTRLESDAWSWLKWLPHTDVPGQNDGVGPARYLATEPAALHALLAP
MAB_2232c|M.abscessus_ATCC_199      VAMAGPGVEDAEWSWLKWLPHVDISGEVDGVGPARYLRRTGAELFEALTP
MAV_4390|M.avium_104                IAAVVGDGDRAHWDWLKWLPHNRHPTHDDALGPMRMVYSTAAQAQQALAG
                                    :* .    :   *.*******   . . *.:*. * :          *  

Rv0284|M.tuberculosis_H37Rv         VLADRPAFTGQPTDALRHLLIVVDDPDYDLG---ASPLAVGRAGVTVVHC
Mb0292|M.bovis_AF2122/97            VLADRPAFTGQPTDALRHLLIVVDDPDYDLG---ASPLAVGRAGVTVVHC
MMAR_0543|M.marinum_M               AILDRPAYAGSAADALRHLLIVVDDPDYDIN---ASMLAMGRAGVTVVHC
MUL_1206|M.ulcerans_Agy99           AILDRPAYAGSAADALRHLLIVVDDPDYDIN---ASMLAMGRAGVTVVHC
MLBr_02535|M.leprae_Br4923          ALTDRPAFTGMSVDALRHLMIVIDEPDYDLN---ASTLVMGRAGVTVVHC
MSMEG_0617|M.smegmatis_MC2_155      ALADRPLFPAESGAALKHLLVVLDDPDADPD---DIARKPGLTGVTVIHR
TH_3306|M.thermoresistible__bu      ALDGRPAFGADT-APVRHLLVVLDDPEADPS---RLVGKAGLAGVTVVHR
Mflv_0327|M.gilvum_PYR-GCK          ALADRSGFTGDATGTTKHLLIVLDDPDADPS---EFIG-SGLAGVTVIHR
Mvan_0413|M.vanbaalenii_PYR-1       ALAERAPFTGDGPTDAKHLLVVLDDPDADPG---QFIG-RGLAGVTVIHR
MAB_2232c|M.abscessus_ATCC_199      VLTERELFGADS-GAHKHLLIILDDPAYDLNGVNSPIPATGLDGVTVIQR
MAV_4390|M.avium_104                LPVARLVLVAERAVAPIAGATVIAIGAGDDG-----------APVTIRTA
                                        *    .           ::     * .             **:   

Rv0284|M.tuberculosis_H37Rv         SA---SAPHREQYSDPEKPILRVA----HGAIERWQTGG-WQPYIDAADQ
Mb0292|M.bovis_AF2122/97            SA---SAPHREQYSDPEKPILRVA----HGAIERWQTGG-WQPYIDAADQ
MMAR_0543|M.marinum_M               SS---TLPHREQYSDPEKPILRIE----DGAITRWQTGGGWQAYIDHADQ
MUL_1206|M.ulcerans_Agy99           SS---TLPHREQYSDPEKPILRIE----DGAITRWQTGGGWQAYIDHADQ
MLBr_02535|M.leprae_Br4923          ST---TPPHREQYSDPDQPILRIV----RGTIERWQTGG-WQPYIDTADR
MSMEG_0617|M.smegmatis_MC2_155      TT---ELPNREQYPDPERPILRVA----DGRIERWQVGG-WQPCVDVADA
TH_3306|M.thermoresistible__bu      SS---AEPHREQYPDPERPILRVV----DGRLERWQSDG-WQPFVDAADR
Mflv_0327|M.gilvum_PYR-GCK          SA---TEPDRDQYSDPERPVLRIS----GGRIERWQNGT-WASNIDSADH
Mvan_0413|M.vanbaalenii_PYR-1       TD---REPDRDQYPDPERPVLRVA----ARRIERWLNGS-WVPFVDAADR
MAB_2232c|M.abscessus_ATCC_199      LDGADGTTKLPDYLNPERPVLQVNRNGVSARIARWNGND-WQPYIDEADQ
MAV_4390|M.avium_104                AG---------------------------------------TVSPSRPDR
                                                                                 . .* 

Rv0284|M.tuberculosis_H37Rv         FSADEAAHLARRLSRWDSNPTHAGLRSAATRGASFTTLLGIEDASRLDVP
Mb0292|M.bovis_AF2122/97            FSADEAAHLARRLSRWDSNPTHAGLRSAATRGASFTTLLGIEDASRLDVP
MMAR_0543|M.marinum_M               LGADEASHLARRLSRWDSNPTHAGLRSAATRGASFTTLLGIPDASQLDVQ
MUL_1206|M.ulcerans_Agy99           LGADEASHLARRLSRWDSNPTHAGLRSAATRGASFTTLLGIPDASQLDVQ
MLBr_02535|M.leprae_Br4923          LGAHEAAHLARQLSRWDSNPTHAGLRSAATRGASFTTLLGIPDASRLDVT
MSMEG_0617|M.smegmatis_MC2_155      MSAAEAAHIARRLSRWDSNPGYI--RSTSTGSATFTTLLGIPDASALDVA
TH_3306|M.thermoresistible__bu      LSAAECRHLARRLARWDSNPMHA--RSTTTGGATFTTLLGIPDASALDVA
Mflv_0327|M.gilvum_PYR-GCK          LGAADARHIARRLARWDSNPDHA--RSATTGGAAFTTLLGIPDASALDVA
Mvan_0413|M.vanbaalenii_PYR-1       MAPDDARHIARRLARWDSNPHHG--RSASAGGAAFTTLLGIPDASALDVA
MAB_2232c|M.abscessus_ATCC_199      LTIGTASHVARRLSRWDSNPTHPGLRSAATGGATFTSLLGIEDASQLDVP
MAV_4390|M.avium_104                MTAADALTCARRLAGQR--------VTAGDGDGGWPGLVGLADVSGFDPA
                                    :    .   **:*:            ::   .. :. *:*: *.* :*  

Rv0284|M.tuberculosis_H37Rv         ALWAPRRRDEELRVPIGVTGTGEPLMFDLKDEAEGGMGPHGLMIGMTGSG
Mb0292|M.bovis_AF2122/97            ALWAPRRRDEELRVPIGVTGTGEPLMFDLKDEAEGGMGPHGLMIGMTGSG
MMAR_0543|M.marinum_M               AIWGQRRRDDELRVPIGITASGEPLMFDLKDEAEGGMGPHGLMIGMTGSG
MUL_1206|M.ulcerans_Agy99           AIWGQRRRDDELRVPIGITAGGEPLMFDLKDEAEGGMGPHGLMIGMTGSG
MLBr_02535|M.leprae_Br4923          TLWAPRRRDDELRIPIGVTGTGEPLMFDLKDEAEGGMGPHGLMIGMTGSG
MSMEG_0617|M.smegmatis_MC2_155      SLWAPRPRDEELRVPIGVTSTGEPLYFDLKDEAEGGMGPHGLMIGMTGSG
TH_3306|M.thermoresistible__bu      SLWAPRPREEELRVPIGVTATGEPLIFDLKDEAEGGMGPHGLMIGMTGSG
Mflv_0327|M.gilvum_PYR-GCK          ALWAPRNRDDELRVPIGVTATGEPLIFDLKDEAEGGMGPHGLMIGMTGSG
Mvan_0413|M.vanbaalenii_PYR-1       ALWAPRNRDDELRVPIGVTATGEPLIFDLKDEAEGGMGPHGLMIGMTGSG
MAB_2232c|M.abscessus_ATCC_199      ALWSPRSRDEELRVPIGVTSSGEPLMFDLKDEAEGGMGPHGLMIGMTGSG
MAV_4390|M.avium_104                TLWGRQTGRDRLRAPLGVAADGTPVELDIKEPAEHGMGPHGLCVGATGSG
                                    ::*. :   :.** *:*::. * *: :*:*: ** ******* :* ****

Rv0284|M.tuberculosis_H37Rv         KSQTLMSILLSLLTTHSAERLIVIYADFKGEAGADSFRDFPQVVAVISNM
Mb0292|M.bovis_AF2122/97            KSQTLMSILLSLLTTHSAERLIVIYADFKGEAGADSFRDFPQVVAVISNM
MMAR_0543|M.marinum_M               KSQTLMSILLSLLTTHSAERLIVIYADFKGEAGADSFRNFPQVVAVISNM
MUL_1206|M.ulcerans_Agy99           KSQTLMSILLSLLTTHSAERLIVIYADFKGEAGADSFRNFPQVVAVISNM
MLBr_02535|M.leprae_Br4923          KSQTLMSILLSLLTTHSADRLIVIYADFKGEAGADSFRNFPQVVAVISNM
MSMEG_0617|M.smegmatis_MC2_155      KSQTLMSILLSLLTTHPADRLIVIYADFKGEAGADIFRHFPQVVAVISNM
TH_3306|M.thermoresistible__bu      KSQTLMSILLSLLTTHPADRLIVIYADFKGEAGADIFRNFPQVVAVISNM
Mflv_0327|M.gilvum_PYR-GCK          KSQTLMSILLSLLTTHPADRLIVIYADFKGEAGADIFRNFPQVVAVISNM
Mvan_0413|M.vanbaalenii_PYR-1       KSQTLMAILLSLLTTHPADRLIVIYADFKGEAGADIFRNFPQVVAVISNM
MAB_2232c|M.abscessus_ATCC_199      KSQTLMSILLSLLATHSADRLIVIYADFKGEAGADIFRDFPQVVAVISNM
MAV_4390|M.avium_104                KSELLRTIALGMMARNSPDVLNLLLVDFKGGATFLDYANAPHVAAVITNL
                                    **: * :* *.::: :..: * :: .**** *    : . *:*.***:*:

Rv0284|M.tuberculosis_H37Rv         AEKKSLADRFADTLRGEVARREMLLREAGRKVQGSAFNSVLEYENAIA--
Mb0292|M.bovis_AF2122/97            AEKKSLADRFADTLRGEVARREMLLREAGRKVQGSAFNSVLEYENAIA--
MMAR_0543|M.marinum_M               AEKKSLADRFADTLRGEVARRETLLREAGRKIQGSAFNSVLEYENARESA
MUL_1206|M.ulcerans_Agy99           AEKKSLADRFADTLRGEVARRETLLREAGRKIQGSAFNSVLEYENARESA
MLBr_02535|M.leprae_Br4923          AEKKSLAERFADTLRGEVARRETLLREAGRRVQGSAFNSVLEYENAIAAG
MSMEG_0617|M.smegmatis_MC2_155      AEKRSLADRFADTLRGEVARREQILKEAGRRVQGSAFNSVAEYESAIA--
TH_3306|M.thermoresistible__bu      AEKRSLAERFADTLRGEVARREQLLREAGRKVQGSAFNSVTEYEEAIE--
Mflv_0327|M.gilvum_PYR-GCK          AEKRSLADRFADTLRGEVARREQLLKDSGRRVQGSAFNSVTEYENAVR--
Mvan_0413|M.vanbaalenii_PYR-1       AEKRSLADRFADTLRGEVARREQLLLEAGRRIQNSAFNSVTEYENAIA--
MAB_2232c|M.abscessus_ATCC_199      AEKRSLADRFADTLRGEVARRENLLKQAGRDVQGSAFNSVREYEEAIA--
MAV_4390|M.avium_104                ADDAPLVARMRAALAGEMNRRQEALRTAG-------CDSVAAYQHARR--
                                    *:. .*. *:  :* **: **:  *  :*        :**  *: *    

Rv0284|M.tuberculosis_H37Rv         --AGHSLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILF
Mb0292|M.bovis_AF2122/97            --AGHSLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILF
MMAR_0543|M.marinum_M               GVAGLDLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILF
MUL_1206|M.ulcerans_Agy99           GVAGLDLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILF
MLBr_02535|M.leprae_Br4923          ---AVDLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILF
MSMEG_0617|M.smegmatis_MC2_155      --AGHDLPPMPTLFVVADEFTLMLAEHPEYADLFDYVARKGRSFRIHLLF
TH_3306|M.thermoresistible__bu      --AGHDLPPLPTLFVVADEFTLMLADYPEYADLFDYVARKGRSFRIHLLF
Mflv_0327|M.gilvum_PYR-GCK          --EGHDLPPIPTLLVVADEFTLMLADHPEYADLFDYVARKGRSFRIHLLF
Mvan_0413|M.vanbaalenii_PYR-1       --EGHDLPPLPTLFVVADEFTLMLAEHPEYADLFDYVARKGRSFRIHLLF
MAB_2232c|M.abscessus_ATCC_199      --AGHDLPPIPTLFVVADEFTLMLQDHPEYAELFDYVARKGRSFRIHILF
MAV_4390|M.avium_104                --SAAALPALPTLFVIVDEFSELLSQQPDFADTFVAIGRLGRSLGIHLLL
                                       .  **.:***:*:.***: :* : *::*: *  :.* ***: **:*:

Rv0284|M.tuberculosis_H37Rv         ASQTLDVGKIKDIDKNTAYRIGLKVASPSVSRQIIGVEDAYHIESGKEHK
Mb0292|M.bovis_AF2122/97            ASQTLDVGKIKDIDKNTAYRIGLKVASPSVSRQIIGVEDAYHIESGKEHK
MMAR_0543|M.marinum_M               ASQTLDVGKIKDIDKNTSYRIGLKVASASVSRQIIGVEDAYHIEAGKEHK
MUL_1206|M.ulcerans_Agy99           ASQTLDVGKIKDIDKNTSYRIGLKVASASVSRQIIGVEDAYHIEAGKEHK
MLBr_02535|M.leprae_Br4923          ASQTLDFGKIKDIDKNTSYRIGLKVANASVSRQIIGVEDAYHIESGKEHK
MSMEG_0617|M.smegmatis_MC2_155      ASQTLDVGRIKDIDKNTSYRIGLKVASPSISRQIIGVEDAYHIESGREHK
TH_3306|M.thermoresistible__bu      ASQTLDVGRIKDIDKNTSYRIGLKVASPSISRQIIGVEDAYHIESGREHK
Mflv_0327|M.gilvum_PYR-GCK          ASQTLDVGRIKDIDKNTSYRIGLKVASPSVSRQIIGVEDAYHIESGREHK
Mvan_0413|M.vanbaalenii_PYR-1       ASQTLDVGRIKDIDKNTSYRIGLKVASPAVSRQIIGVEDAYHIESGREHK
MAB_2232c|M.abscessus_ATCC_199      ASQTLDVGKIKDIDKNTSYRIGLKVASPSASRQIIGTEDAYHIESGKDHK
MAV_4390|M.avium_104                ASQRLDEGRLRGLDAHLSYRLCLKTLSEAESRAVLGNLDAYHLPTDP---
                                    *** ** *:::.:* : :**: **. . : ** ::*  ****: :.    

Rv0284|M.tuberculosis_H37Rv         GVGFLVPAPGATPIRFRSTYVDGIYEPPQTAKAVVVQSVPEPKLFTAAAV
Mb0292|M.bovis_AF2122/97            GVGFLVPAPGATPIRFRSTYVDGIYEPPQTAKAVVVQSVPEPKLFTAAAV
MMAR_0543|M.marinum_M               GVGFLVPAPGAAPIRFRSTYVDGIYEPPQQTKTRVVHNIPEPKLFTATAV
MUL_1206|M.ulcerans_Agy99           GVGFLVPAPGAAPIRFRSTYVDGIYEPPQQTKTRVVHNIPEPKLFTATAV
MLBr_02535|M.leprae_Br4923          GMGFLVPSPGAAPIKFRSTYVDGIYEPPRSTKVRVVEVTPEPKLFTAGVV
MSMEG_0617|M.smegmatis_MC2_155      GEGFLVPAPGAVPIKFRSTYVDGIYDPPRAEKSIVVHALPQPQVFTAGRV
TH_3306|M.thermoresistible__bu      GVGFLVPAPGAVPIKFRSTYVDGIYEPPVREKAIAVHADPRPKLFSATRV
Mflv_0327|M.gilvum_PYR-GCK          GVGFLVPAPGALPVKFRSTYVDGIYEPPRVDRSIVVHAIPKPQLFSAGWV
Mvan_0413|M.vanbaalenii_PYR-1       GEGFLVPAPGALPIKFRSTYVDGIYEPPRVDRSIVVHAIPKPQLFSAGWV
MAB_2232c|M.abscessus_ATCC_199      GVGFLVPAPGAVPIKFRSTYVDGIYEPPSTTTTVEIRATPQPKQFTALPV
MAV_4390|M.avium_104                GAGYLRVG-AGAPIRFQAALVSGPLRPDTAPRPPAMVRVFGTRVVGPVSR
                                    * *:*  . .. *::*::: *.*   *        :     .: . .   

Rv0284|M.tuberculosis_H37Rv         EPDPGTVIADTDEQEPADPPRKLIATIGEQLARYGPRAPQLWLPPLDETI
Mb0292|M.bovis_AF2122/97            EPDPGTVIADTDEQEPADPPRKLIATIGEQLARYGPRAPQLWLPPLDETI
MMAR_0543|M.marinum_M               EPDPDTVISEVEEEHPVGPPRKLIATIGEQLARYGPQAPRLWLPPLDEPI
MUL_1206|M.ulcerans_Agy99           EPDPDTVISEVEEEHPVGPPRKLIATIGEQLARYGPQAPRLWLPPLDEPI
MLBr_02535|M.leprae_Br4923          EPDHPIVISSEDEDESVAPPRKLIATIGEQLARYEPRAPKLWLPPLDESI
MSMEG_0617|M.smegmatis_MC2_155      EPEPDTVIATGDVEVHTAPPRKLIATIGDQLAAYGPKAPQLWLPPLDEPI
TH_3306|M.thermoresistible__bu      EPDPGTVVEVAE--------------------------------------
Mflv_0327|M.gilvum_PYR-GCK          DPEPDTVIVDDGADVEVLPPRKLIATIGEQLVHYGPRAPQLWLPPLEEAI
Mvan_0413|M.vanbaalenii_PYR-1       DPEPDTVIVDDGADVEVLPPRKLITTIGEQLAQYGPRAPQLWLPPLDEPI
MAB_2232c|M.abscessus_ATCC_199      AADPTTVIVKGGSDRPAQPARKLISTVGDQLAKVGPRAPQLWLPPLDTAI
MAV_4390|M.avium_104                PVEAAHPS-----------GRSISAAVLDRLAGHGPAAHRVWLPPLGRPP
                                      :                                               

Rv0284|M.tuberculosis_H37Rv         PLSAALARAGVGPRQWRWPLGEIDRPFEMRRDPLVFDARSSAGNMVIHGG
Mb0292|M.bovis_AF2122/97            PLSAALARAGVGPRQWRWPLGEIDRPFEMRRDPLVFDARSSAGNMVIHGG
MMAR_0543|M.marinum_M               PLSTLLATAGVAQRQWRWPLGEIDKPFEMRRDPLVFDATSSAGNLVIHGG
MUL_1206|M.ulcerans_Agy99           PLSTLLATAGVAQRQWRWPLGEIDKPFEMRRDPLVFDATSSAGNLVIHGG
MLBr_02535|M.leprae_Br4923          QLTAILASAEVPQRQWRWPLGEIDKPFEMRRDLLMFDANSSAGNMVIHGG
MSMEG_0617|M.smegmatis_MC2_155      ALADVLAGADVEPGQLRWPLGEIDKPFEMRRDVLVYDAHTAAANVLIHGG
TH_3306|M.thermoresistible__bu      -----------PPGXX-------------------------------XGG
Mflv_0327|M.gilvum_PYR-GCK          PLQGLLERSGIGAGQWRWPLGEIDRPFDMRRDPLVFDATSAAANMVIHGG
Mvan_0413|M.vanbaalenii_PYR-1       PLRDVLERAGVGARQWRWPLGEIDRPFEMRRDPLIFDATSAAANMVIHGG
MAB_2232c|M.abscessus_ATCC_199      PLASVLDETGLPARQLRWPLGEIDKPFQMRRDPLIFDATSAAGNVIIHGG
MAV_4390|M.avium_104                ELRTLLG----GAADLTVPVGLVDRPFEQCRTPLIVDLSGAAGNVAVVGA
                                                                                    *.

Rv0284|M.tuberculosis_H37Rv         PKSGKSTALQTFILSAASLHSPHEVSFYCLDYGGGQLRALQDLAHVGSVA
Mb0292|M.bovis_AF2122/97            PKSGKSTALQTFILSAASLHSPHEVSFYCLDYGGGQLRALQDLAHVGSVA
MMAR_0543|M.marinum_M               PKSGKSTALQSFMLSAASLHSPSEVTFYCLDYGGGQLRALQDLAHVGSVA
MUL_1206|M.ulcerans_Agy99           PKSGKSTALQSFMLSAASLHSPSEVTFYCLDYGG-QLRALQDLAHVGSVA
MLBr_02535|M.leprae_Br4923          PKSGKSTALQTFILSAASLHSPRDVTFYCLDYGGGQLRAIQDLLHIGSVA
MSMEG_0617|M.smegmatis_MC2_155      PRSGKSTALQAFVLSAAALHSPRAITFYCLDYGGGKLADLADLAHVGSVA
TH_3306|M.thermoresistible__bu      GRNDR-----------------------RRDRGG----------------
Mflv_0327|M.gilvum_PYR-GCK          PKSGKSTALQTFVLSAAALHAPGDVSFYCLDYGGGQLRVLDGLAHVGSVA
Mvan_0413|M.vanbaalenii_PYR-1       PKSGKSSALQTFVLSAAALHAPGDVSFYCLDYGGGQLRALENLAHVGSVA
MAB_2232c|M.abscessus_ATCC_199      PKSGKSTALQTFMLSAAALHSPRDVTFYCIDYGGGQLHALDGLAHVGSVA
MAV_4390|M.avium_104                PRSGKSTALRTLITALAATHDPARVQFYCLDFGGGALSSLHTLPHVGAVA
                                     :..:                         * **                

Rv0284|M.tuberculosis_H37Rv         SALEPERIRRTFGELEQLLLSRQ-----QREVFRDRGANG----STPDDG
Mb0292|M.bovis_AF2122/97            SALEPERIRRTFGELEQLLLSRQ-----QREVFRDRGANG----STPDDG
MMAR_0543|M.marinum_M               SALEPERIRRTFGELEQLLLARQ-----QREVFRDRGGNGQAHGSVPDDG
MUL_1206|M.ulcerans_Agy99           SALEPERIRRTFGELEQLLLARQ-----QREVFRDRGGNGQVHGSVPDDG
MLBr_02535|M.leprae_Br4923          SALEPERIRRTFGELEQLLLSRQ-----QREVFRDKRASG----SAPDDC
MSMEG_0617|M.smegmatis_MC2_155      TPLEPERIRRTFGELEQLLRARQ-----RQGAVNRT--------GSYTDG
TH_3306|M.thermoresistible__bu      ---------RRFGAADHHHHDQD-----DQEHHQRH--------RRRGD-
Mflv_0327|M.gilvum_PYR-GCK          SPLESERIRRTFGELEQLLQARQ-----RHGAAVNN--------GGYRDG
Mvan_0413|M.vanbaalenii_PYR-1       SPLEPERIRRTFGELEHLLRARQ-----QHGAAAAD--------GQYRDG
MAB_2232c|M.abscessus_ATCC_199      SALEPERIRRTFGELEQLLAYRQRLFRDRGIASVSQLRALRDSDRTLDDG
MAV_4390|M.avium_104                GRAEPRRVGRIVAECEAVVGRREAFFGEHAIASIADYRQR----RPGSDP
                                             * ..  :     ::                         * 

Rv0284|M.tuberculosis_H37Rv         FGEVFLVIDNLYGFGRDNTDQFNTRNPLLARVTELVNVGLAYGIHVIITT
Mb0292|M.bovis_AF2122/97            FGEVFLVIDNLYGFGRDNTDQFNTRNPLLARVTELVNVGLAYGIHVIITT
MMAR_0543|M.marinum_M               FGEVFLVIDNLYAFSRDNTDQFNTRNPLLARVTELVNVGMAYGIHVIITT
MUL_1206|M.ulcerans_Agy99           FGEVFLVIDNLYAFSRDNTDQFNTRNPLLARVTELVNVGMAYGIHVIITT
MLBr_02535|M.leprae_Br4923          FGDVFLVIDNLYAFGRDNTDQFNTRNPLLAKVTELVNVGLAYGIHVIITT
MSMEG_0617|M.smegmatis_MC2_155      YGEVFLVIDNLYAFSRDNTDTFNTRNPLLAKVTELANSGLAYGIHVVITT
TH_3306|M.thermoresistible__bu      --------------HREYAAPFTS--------------------------
Mflv_0327|M.gilvum_PYR-GCK          YGEVFLLIDNLYAFSRDNTDTFNTRNPLLAKVTELVNTGLAYGIHVVITT
Mvan_0413|M.vanbaalenii_PYR-1       YGEVFLLIDNLYAFSRDNTDTFNARNPLLARVTELVNTGLSYGIHVVVTT
MAB_2232c|M.abscessus_ATCC_199      YGETFLIVDNLYAFSRDNTDQFNTRNPLLARLTELANAGLSYGIHVVITT
MAV_4390|M.avium_104                FGDVFLVIDGWAVLRRDFET-------LEASIIALAGQGLSFGVHLVLSA
                                                   *:                                 

Rv0284|M.tuberculosis_H37Rv         PSWLEVPLAMRDGLGLRLELRLHDARDSNVRVVG---ALRRPADAVPHDQ
Mb0292|M.bovis_AF2122/97            PSWLEVPLAMRDGLGLRLELRLHDARDSNVRVVG---ALRRPADAVPHDQ
MMAR_0543|M.marinum_M               PSWLEVPLAMRDGLGMRLELRLHDARDSNVRVVG---ALRRPAESVPHDQ
MUL_1206|M.ulcerans_Agy99           PSWLEVPLAMRDGLGMRLELRLHDARDSNVRVVG---ALRRPAESVPHDH
MLBr_02535|M.leprae_Br4923          SSWLEVPLVMRDGFGLRLELKLPDARDSNVRVVG---ALRRPADAVPHDQ
MSMEG_0617|M.smegmatis_MC2_155      PNWLEVPLAMRDGLGLRLELKLHDSHDSIVRVAG---ALRRPADSVPADQ
TH_3306|M.thermoresistible__bu      --------------------------------------------------
Mflv_0327|M.gilvum_PYR-GCK          PNWLEVPLAMRDGLGLRLELRLHDAHDSNVRVVG---ALRRPAEGVPADQ
Mvan_0413|M.vanbaalenii_PYR-1       PNWLEVPLTMRDGLGLRLELRLHDPRDSNVRVVSKDAALRRPAESVPADQ
MAB_2232c|M.abscessus_ATCC_199      PNWIEVPLAMRDSLGLRLELKLHDSADSNVRVPG---ALRRPAESVPHDQ
MAV_4390|M.avium_104                SRWADIRPALRDQIGTRIELRLGDPADSEID--------RRAAAHVPRDS
                                                                                      

Rv0284|M.tuberculosis_H37Rv         PGRGLTMAAEHFLFAAPELDAQTNPVAAINARYPGMAAPPVRLLPTNLAP
Mb0292|M.bovis_AF2122/97            PGRGLTMAAEHFLFAAPELDAQTNPVAAINARYPGMAAPPVRLLPTNLAP
MMAR_0543|M.marinum_M               PGRGLTMAAEHFLFAAPELDQVP----AINARYPGMAAPPVRLLPIDLAP
MUL_1206|M.ulcerans_Agy99           PGRGLTMAAEHFLFAAPELDQVP----AINARYPGMAAPPVRLLPIDLAP
MLBr_02535|M.leprae_Br4923          PGRGLTMAAEHFLFAAPQLDQVA----VINARHAGVAAPPVRLLPANLAP
MSMEG_0617|M.smegmatis_MC2_155      PGRGLTMAAEHFLFAEPALSDIA----VINARYPGVSAPPVRLLPTDLSP
TH_3306|M.thermoresistible__bu      --------------------------------------------------
Mflv_0327|M.gilvum_PYR-GCK          PGRGLTMAAEHFLFARPAPETIP----ALNARFPGQSAPEVRLLPTRLSP
Mvan_0413|M.vanbaalenii_PYR-1       PGRGLTMAVEHFLFAAPATESIP----ALNARYPGRSAPPVRLLPTDLSP
MAB_2232c|M.abscessus_ATCC_199      PGRGLTMQAEHFLFAASDAKTVD----SVNANYPGAKAPAVRLLPADLAP
MAV_4390|M.avium_104                PGRGLSHDGLHMVIASPVADVAAG----------ESVAPPIPLLPARVDL
                                                                                      

Rv0284|M.tuberculosis_H37Rv         HAV--GELYRGPDQLVIGQREEDLAPVILDLAANPLLMVFGDARSGKTTL
Mb0292|M.bovis_AF2122/97            HAV--GELYRGPDQLVIGQREEDLAPVILDLAANPLLMVFGDARSGKTTL
MMAR_0543|M.marinum_M               DAV--GNLYRGPDQIVIGQREEDLAPVVLNLAENPLLMVFGDSKSGKTTL
MUL_1206|M.ulcerans_Agy99           DAV--GNLYRGPDQIVIGQREEDLAPVVLNLAENPLLMVFGDSKSGKTTL
MLBr_02535|M.leprae_Br4923          DAV--GALYRGPEQVVIGQREEDLAPVVVDFANNPLLMVFGDSKSGKTTL
MSMEG_0617|M.smegmatis_MC2_155      DAL--APLYPAPETVVIGQREEDLAPVAVDFANHPLLMVFGDSKSGKTTL
TH_3306|M.thermoresistible__bu      --------------AVLGHRR------------------------SRSSP
Mflv_0327|M.gilvum_PYR-GCK          RAF--ASLYPAPERVVIGQREEDLAAVSVDFADNPLLMVFGDTKTGKTTL
Mvan_0413|M.vanbaalenii_PYR-1       SAF--PTLYPAPERVVVGQREEDLAAVTVDFGDNPLMMVFGDAKTGKTTL
MAB_2232c|M.abscessus_ATCC_199      GAI--GPLYPGREQVVIGQREQDLAPVALDFSHNPLLMVLGDTGSGKTTL
MAV_4390|M.avium_104                DAVRRGSGDEFAGRPLLGLQERQLQPLAIDFARESHLLILGANGCGKTAA
                                                   ::* :.                        .::: 

Rv0284|M.tuberculosis_H37Rv         LRHIIRTVREHSTADRVAFTVLDRRLHLVDEPLFPDNE-YTANIDRIIPA
Mb0292|M.bovis_AF2122/97            LRHIIRTVREHSTADRVAFTVLDRRLHLVDEPLFPDNE-YTANIDRIIPA
MMAR_0543|M.marinum_M               LRHIIRTVREHSTEDQVAFTVLDRRLHLVDEPLFPENE-YTANIDRIVPA
MUL_1206|M.ulcerans_Agy99           LRHIIRTVREHSTEDQVAFTVLDRRLHLVDEPLFPENE-YTANIDRIVPA
MLBr_02535|M.leprae_Br4923          LRHIIRTIREHSSPDQVAFIVLDRRLHLVDEPLFPDNE-YTANIDRIIPA
MSMEG_0617|M.smegmatis_MC2_155      LRHIIRTVRENSTPDQVAFTVIDRRLHLVDEPLFPDNE-YTANIDRVLPA
TH_3306|M.thermoresistible__bu      FRYFLGPSRTCATP------------------------------------
Mflv_0327|M.gilvum_PYR-GCK          LRHLIRTLRENSRADQVAFTVIDRRLQLVDEPIFPDNE-YTPNIDRILPA
Mvan_0413|M.vanbaalenii_PYR-1       LRHLIRTIRENSRPDQVAFTVIDRRLQLVDEPIFPDNE-YTPNIDRITPA
MAB_2232c|M.abscessus_ATCC_199      LRHIIRTVREHSTPDQVAFTVLDRRLHLVDEPLFPENE-YTPNIDRITPA
MAV_4390|M.avium_104                LRTLCRELVRTNTAAQAQLVIVDFRRALLGIVESEQLRGYAMSPAALTAL
                                    :* :                                              

Rv0284|M.tuberculosis_H37Rv         MLGLANLIEARRPPAGMSAAELSRWTFAG-------HTHYLIIDDVDQVP
Mb0292|M.bovis_AF2122/97            MLGLANLIEARRPPAGMSAAELSRWTFAG-------HTHYLIIDDVDQVP
MMAR_0543|M.marinum_M               MLGLANLIDSRRPPAGMSAAELARWTYQG-------HTHYLIIDDVDQIP
MUL_1206|M.ulcerans_Agy99           MLGLANLIDSRRPPTGMSAAELARWTYQG-------HTHYLIIDDVDQIP
MLBr_02535|M.leprae_Br4923          MLGLANLIEARRPPVGLSAAELSRWAFAG-------HIHYLLIDDVDQVP
MSMEG_0617|M.smegmatis_MC2_155      MLGLSALIEKRRPPAGLSAQELSRWTYTG-------HTHYLIVDDVDQIP
TH_3306|M.thermoresistible__bu      --------------------------------------------------
Mflv_0327|M.gilvum_PYR-GCK          MLGLAGLLEKRRPPAGLSPQELRGWDFRSSANGSGSHLHYLIIDDVDQIP
Mvan_0413|M.vanbaalenii_PYR-1       MLGLSALLEKRRPPAGLSPQELSRWDFRAGANGSGRHLHYLIIDDVDQIP
MAB_2232c|M.abscessus_ATCC_199      MLGLGALLEKRRPPAGLSPEELHSWVSRG----VTAQRHYLIIDDVDQIP
MAV_4390|M.avium_104                LPGLLDLLSGRMPPPDASQAQLRAGSWWS------GPDVYVVVDDYDLVA
                                                                                      

Rv0284|M.tuberculosis_H37Rv         DSPAMTGPYIGQRPWTPLIGLLAQAGDLGLRVIVTGRATGSAHLLMTSPL
Mb0292|M.bovis_AF2122/97            DSPAMTGPYIGQRPWTPLIGLLAQAGDLGLRVIVTGRATGSAHLLMTSPL
MMAR_0543|M.marinum_M               DTAAMSGPFAGQRPWTPLIGLLAQAADLGLRVIVTARASGSAHALMTSPL
MUL_1206|M.ulcerans_Agy99           DTAAMSGPFAGQRPWTPLIGLLAQAADLGLRVIVTARASGSAHALMTSPL
MLBr_02535|M.leprae_Br4923          DSPAMSGPYIGQRPWTNLIGLLGQAGDLGLRVIVTGRATGSGHALMTNQL
MSMEG_0617|M.smegmatis_MC2_155      DTPAVSGPFVGQRPWTNIVGLLAEAADLGLRVIVTARATGSAHAVMTAPL
TH_3306|M.thermoresistible__bu      ----------APRPRR------------ARRTRVCASRAVRTRSECTRPS
Mflv_0327|M.gilvum_PYR-GCK          DGPAVSGPYAGQRPWTPVIGLLSQASELGLRVIVTARAAGSAHAVMTAPL
Mvan_0413|M.vanbaalenii_PYR-1       DGPAISGPFAGQRPWTALIGLLAQASDLGLRVIVTARAAGSAHAVMTAPL
MAB_2232c|M.abscessus_ATCC_199      DAPAVSGPYIGQRPWNPITGLLAEARELGLRVIITARATGSGHILMTNPM
MAV_4390|M.avium_104                SP--------SGNLLAPLVEFLPYASELGLHLIIARRSGG-AERAMFEPL
                                              . .               . :  :        .       

Rv0284|M.tuberculosis_H37Rv         LRRFNDLQATTLMLAGNPADSGKIRGERFARLPAGRAILLTD---SDSPT
Mb0292|M.bovis_AF2122/97            LRRFNDLQATTLMLAGNPADSGKIRGERFARLPAGRAILLTD---SDSPT
MMAR_0543|M.marinum_M               LRRFNDLQATTLMLAGNPQDSGKIRGQRFSRLPAGRAMLLGD---SDDPT
MUL_1206|M.ulcerans_Agy99           LRRFNDLQATTLMLAGNPQDSGKIRGQRFSRLPAGRAMLLGD---SDDPT
MLBr_02535|M.leprae_Br4923          LRRLNDLQATTLMLAGNPADSGKIRGQRFSRLPAGRAILLSD---SNSPT
MSMEG_0617|M.smegmatis_MC2_155      LRRLNDLQATTLMLSGNPTDSGKIRGHRFARFPAGRGLLLTD---TDTPD
TH_3306|M.thermoresistible__bu      PR------------------------------------------------
Mflv_0327|M.gilvum_PYR-GCK          LRRLNELQATTLLLSGNPQDSGKIRGHRFSRLPAGRGLLLDDSNLSDTPT
Mvan_0413|M.vanbaalenii_PYR-1       LRRLNDLQATTFLLSGNPADSGKIRGHRFARLPVGRAMLLDDRNSSGSPT
MAB_2232c|M.abscessus_ATCC_199      LRRFHELQANTLMLSGSPQDGGRIRGHRFERLPAGRGILLSD---NDVPT
MAV_4390|M.avium_104                LAGLRDLGCMSLTMSEAAPFAAAPP------LPPGRGVLTTR---AGADE
                                                                                      

Rv0284|M.tuberculosis_H37Rv         YVQLINPLVDAAAVSGETQQKGSQS-----
Mb0292|M.bovis_AF2122/97            YVQLINPLVDAAAVSGETQQKGSQS-----
MMAR_0543|M.marinum_M               YVQLVNPLVGEAATVTETQQKGN-------
MUL_1206|M.ulcerans_Agy99           YVQLVNPLVGEAATVTETQQKDSY------
MLBr_02535|M.leprae_Br4923          YVQLVNPLAGESVP--ERVNDGGFL-----
MSMEG_0617|M.smegmatis_MC2_155      HIQLVNPLGDAALSGNIGNNGNHNRGGEYR
TH_3306|M.thermoresistible__bu      ------------------------------
Mflv_0327|M.gilvum_PYR-GCK          YVQLVDPLADDATAPAGHLGKEYS------
Mvan_0413|M.vanbaalenii_PYR-1       FVQLVNPLAERTAARSGHSGKEYS------
MAB_2232c|M.abscessus_ATCC_199      YVQTVNPLVSEHAAQGREYPR---------
MAV_4390|M.avium_104                LVQVAWSPP---------------------