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TTRKFTPIIKRGPRLTPGEINVAPPEDLGVDIPPSGMQKALPWVMGGCMLGMIAILIFGGLRNFSPYMLM MPMMVVMGAVGMMASGGSGGKKVPEINADRKEYLRYLAGLRTRVTSSAAAQVSFFNYHAPHPDDLLSIVG THRQWSRAANHDFYAATRIGLGSEPAVDRLLKPAVGAELAGPAGAPQPHLEPVSHMWVTKFLRTHGLIHD CPKLLQLRTFPTIAVGGDTDGAVGLLTAMICHLAVFHPPDMLQMRVLTDNPEDPVWAWLKWLPHLQHQTD TDAAGATRMVFTRTDGLSDLAARGPHTADATPSGPYVVVIDLTGGRAGFPMDGRSGVTVLTLGNHRSTYR IRVDAGDGTADDKLPGASFRLVASEVDRMSPAQAERLARKLAGWSITGTIIDKGTRVQKKVATEWHEIVG AQSVEEVTPARWRMFTDTDRDRLRIPFGHELKTGDVMYLDIKEGAEFGAGPHGMLIGTTGSGKSEFLRTL ILSLAATHHPDQINLLLTDFKGGSTFLGMEKLPHTAAVVTNMEEEAELVSRMGEVLTGELDRRQSILRQA GIQVGAAGALSGVAEYEKHRERGADLPPLPTLFVVVDEFAELLQNHPDFIGLFDRICRVGRSLRVHLLLA TQSLNTGGTRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNKESGVGFLRVGMEDPVKFQSVYTG TPYVPVTVGAGDDDTPRAHADSGIRIHRFTTAPIADTRVTV*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0771 | - | - | 100% (742) | cell divisionFtsK/SpoIIIE |
M. gilvum PYR-GCK | Mflv_4959 | - | 3e-95 | 34.07% (675) | cell divisionFtsK/SpoIIIE |
M. gilvum PYR-GCK | Mflv_0327 | - | 2e-94 | 32.27% (719) | cell divisionFtsK/SpoIIIE |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3900 | - | 0.0 | 80.32% (747) | hypothetical protein Mb3900 |
M. tuberculosis H37Rv | Rv3870 | - | 0.0 | 80.32% (747) | transmembrane protein |
M. leprae Br4923 | MLBr_00053 | - | 0.0 | 78.12% (745) | hypothetical protein MLBr_00053 |
M. abscessus ATCC 19977 | MAB_3756c | - | 1e-133 | 39.08% (742) | putative FtsK/SpoIIIE family protein |
M. marinum M | MMAR_5445 | - | 0.0 | 78.02% (746) | hypothetical protein MMAR_5445 |
M. avium 104 | MAV_4390 | - | 1e-105 | 36.77% (699) | ftsk/SpoIIIE family protein |
M. smegmatis MC2 155 | MSMEG_0061 | - | 0.0 | 82.91% (743) | ftsk/SpoIIIE family protein |
M. thermoresistible (build 8) | TH_4195 | - | 0.0 | 85.98% (742) | PUTATIVE cell divisionFtsK/SpoIIIE |
M. ulcerans Agy99 | MUL_0860 | - | 1e-104 | 35.63% (727) | hypothetical protein MUL_0860 |
M. vanbaalenii PYR-1 | Mvan_0074 | - | 0.0 | 93.51% (740) | cell divisionFtsK/SpoIIIE |
CLUSTAL 2.0.9 multiple sequence alignment Mb3900|M.bovis_AF2122/97 MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAM Rv3870|M.tuberculosis_H37Rv MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAM MMAR_5445|M.marinum_M MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAM MLBr_00053|M.leprae_Br4923 MTTKKFTPTITRGPRLTPGEINITPPDDLGLEIPPSGIQKILPYVMVGCI Mflv_0771|M.gilvum_PYR-GCK MTTRKFTPIIKRGPRLTPGEINVAPPEDLGVDIPPSGMQKALPWVMGGCM Mvan_0074|M.vanbaalenii_PYR-1 MTTRKFTPIIKRGPRLTPGEINVTPPEDLGVDIPPSGMQKALPWVMGGCM MSMEG_0061|M.smegmatis_MC2_155 MTTKKFTPTIKRGPRLTPGEINVAPPDDLGIDIPPSGMQKALPWVMGGCM TH_4195|M.thermoresistible__bu MTTRKFTPTIKRGPRLTPGEINVTPPEDLGVEIPPSGVQKALPWVMGGCM MAV_4390|M.avium_104 ---------------MTQADIVVEAPPELPAPESTGLPARLLPVALSVAG MUL_0860|M.ulcerans_Agy99 ----------------MTEDLVVAAPPELAQTTSTGPLLRLVPLAMSIAT MAB_3756c|M.abscessus_ATCC_199 ---------------MPGGEVNVQPPPEIPRPVPSPIIAKIMPLVMVVAM :: : .* :: .. : :* .: . Mb3900|M.bovis_AF2122/97 LGMIAIMVAGG--------TRQLSPYMLMMPLMMIVMMVGGLAGSTGGGG Rv3870|M.tuberculosis_H37Rv LGMIAIMVAGG--------TRQLSPYMLMMPLMMIVMMVGGLAGSTGGGG MMAR_5445|M.marinum_M LGMIVIMVAGG--------TRQLSPYMLMMPLMMIVMMVGTLAGGSGGGS MLBr_00053|M.leprae_Br4923 VGMIAIMVLGG--------TKQLSPYMLMMPIMMVMMMAGGSGG--GGGG Mflv_0771|M.gilvum_PYR-GCK LGMIAILIFGG--------LRNFSPYMLMMPMMVVMGAVGMMASG-GSGG Mvan_0074|M.vanbaalenii_PYR-1 LGMIAILIFGG--------MRNFSPYMLMMPMMVVMGAVGMMAGG-GSGG MSMEG_0061|M.smegmatis_MC2_155 LGMIAIMVFTG--------VRQLSPYMLMMPLMMIMGTVGFMAGG-GSGG TH_4195|M.thermoresistible__bu LGMIAIMVFTG--------IRNLSPYMLMMPLMMVMATVGFMAGG-GPGG MAV_4390|M.avium_104 IGVMTVVFASG-------GAAARQPAFLAFPATMLVSTVAAALIG-RSR- MUL_0860|M.ulcerans_Agy99 LIAMAATYVSG-------APSARNPTMLVLPATMSLSLMVMAVSA-RGR- MAB_3756c|M.abscessus_ATCC_199 VGMIAFFVTSGSFGGGAGGGMMRSPMFMLFPIMMMVSMVSMVSNS-GGKG : :. * .* :: :* : : Mb3900|M.bovis_AF2122/97 KKVPEINADRKEYLRYLAGLRTRVTSSATSQVAFFSYHAPHPEDLLSIVG Rv3870|M.tuberculosis_H37Rv KKVPEINADRKEYLRYLAGLRTRVTSSATSQVAFFSYHAPHPEDLLSIVG MMAR_5445|M.marinum_M KKVPEINADRKEYLRYLAGLRGRVTTSATSQVSFFGYHAPHPDDLLSIVG MLBr_00053|M.leprae_Br4923 KKVPEINADRKEYLRYLAGLRARVTSSAASQVAFFSYHAPHPQDLLSIVG Mflv_0771|M.gilvum_PYR-GCK KKVPEINADRKEYLRYLAGLRTRVTSSAAAQVSFFNYHAPHPDDLLSIVG Mvan_0074|M.vanbaalenii_PYR-1 KKVPEINADRKEYLRYLAGLRTRVTSSASAQVTFFNYHGPHPDDLLSIIG MSMEG_0061|M.smegmatis_MC2_155 KKVPEINADRKEYLRYLAGLRTRVTSSASAQVAFFAYHAPHPDDLLSIIG TH_4195|M.thermoresistible__bu KRVPEINADRKEYLRYLAGLRNRVTSSAAAQVTFFAYHAPHPDDLLSIVG MAV_4390|M.avium_104 RGGGGLDADRGRYLEYLNQLGRSVSEIAAAQCASALRDHPDPDTLWTLIG MUL_0860|M.ulcerans_Agy99 RRGAGLDQDRVGYLQYLSELRQRVTEIAAAQRISSNRTHPEPDTVWTLIG MAB_3756c|M.abscessus_ATCC_199 AKTSEINEDRKDYLRYLEVVRKNVTDTGAAQRKALLWNNPDPSALWTLAG :: ** **.** : *: .::* *.*. : :: * Mb3900|M.bovis_AF2122/97 TQRQWSRPANADFYAATRIGIGDQPAVDRLLKPAVGGELAAASAAPQPFL Rv3870|M.tuberculosis_H37Rv TQRQWSRPANADFYAATRIGIGDQPAVDRLLKPAVGGELAAASAAPQPFL MMAR_5445|M.marinum_M TQRQWSRPANSDFYAAARIGIGDQPAVDRLLKPAVGGELAASSAAPQPYL MLBr_00053|M.leprae_Br4923 TQRQWSRPANADFYAATRIGVGDQPAVDRLLKPAVGGELTASGAAPQPFL Mflv_0771|M.gilvum_PYR-GCK THRQWSRAANHDFYAATRIGLGSEPAVDRLLKPAVGAELAGPAGAPQPHL Mvan_0074|M.vanbaalenii_PYR-1 THRQWSRPANHDFYAATRIGLGSEPAVDRLLKPAVGSELAGPAGAPQPHL MSMEG_0061|M.smegmatis_MC2_155 THRQWARQANSEFFAATRIGIGAEIAVDRLLKPNTSGELAGGQAAPAPHL TH_4195|M.thermoresistible__bu THRQWSRQTNADFYAAVRIGIGSEPAVDRLLKPSVGAELVGPQGAPQPHL MAV_4390|M.avium_104 GPRMWRRRPTGPDFCVVRVGMGVLPLARRVVAPPVP---------AEEVR MUL_0860|M.ulcerans_Agy99 GSRMWERRPADADFCRIRIGLGTQPLATRLVAAPLP---------PPHRS MAB_3756c|M.abscessus_ATCC_199 GRRMWERRPGDSDYCHVRVGTGDQRLAAQLVAPEIG---------PVEEL * * * . :. *:* * . ::: . . Mb3900|M.bovis_AF2122/97 EPVSHMWVVKFLRTHGLIHDCPKLLQLRTFPTIAIGGDLAGAAGLMTAMI Rv3870|M.tuberculosis_H37Rv EPVSHMWVVKFLRTHGLIHDCPKLLQLRTFPTIAIGGDLAGAAGLMTAMI MMAR_5445|M.marinum_M EPVSHMWVVKFLRTHGLIHDCPKLVQLRSFPTIAIGGDRPGADRLLTAMI MLBr_00053|M.leprae_Br4923 EPVSHMWVVKFLRTHGLVHDCPKLLQMRTFPTIAVGGDTAGAGGLLTAMI Mflv_0771|M.gilvum_PYR-GCK EPVSHMWVTKFLRTHGLIHDCPKLLQLRTFPTIAVGGDTDGAVGLLTAMI Mvan_0074|M.vanbaalenii_PYR-1 EPVSHMWVTKFLRTHGLIHDCPKLVQLKTFPTIAVGGDSAGSAALLAAMI MSMEG_0061|M.smegmatis_MC2_155 EPVSHMWVTKFLRTHGLIHDCPKLVQLRTFPTVAVGGDPEAAEGLLTSMI TH_4195|M.thermoresistible__bu EPVSHMWVTKFLRTHGLIHDCPKLVQLRTFPTIAIGGDPEGAARLLTAMI MAV_4390|M.avium_104 DPVTATALRRFLHTHATVPG-PVTVDLGAGSPVTIDGDAGAARAVLRAVV MUL_0860|M.ulcerans_Agy99 DPVTVSALRRFLEAHARVTDVPIAIALHGAGVVTIGGDPARVRALLRAMV MAB_3756c|M.abscessus_ATCC_199 EPVASVALRRFVRTHSLVPELPIALNLRGFAAVTIDGSPEVARGMLRAMI :**: : :*:.:*. : * : : :::.*. :: ::: Mb3900|M.bovis_AF2122/97 CHLAVFHPPDLLQIRVLTEEPDDPDWSWLKWLPHVQHQTETDAAGSTRLI Rv3870|M.tuberculosis_H37Rv CHLAVFHPPDLLQIRVLTEEPDDPDWSWLKWLPHVQHQTETDAAGSTRLI MMAR_5445|M.marinum_M CHLAVFHPPDLLQIRVLTEDPEDPDWSWLKWLPHVQHQTETDGAGPVRMI MLBr_00053|M.leprae_Br4923 CHLAVFHPPDLLQIRVLTEKPDDPNWSWLKWLPHIQHPTETDAAGAARMI Mflv_0771|M.gilvum_PYR-GCK CHLAVFHPPDMLQMRVLTDNPEDPVWAWLKWLPHLQHQTDTDAAGATRMV Mvan_0074|M.vanbaalenii_PYR-1 CHLAVFHPPDMLQMRVLTDDPEDPAWAWLKWLPHLQHETDTDAAGTTRMV MSMEG_0061|M.smegmatis_MC2_155 CHLAVFHPPDLVQIRVLTDNPEDPKWSWLKWLPHTQHQTDTDAAGPTRLV TH_4195|M.thermoresistible__bu CHLAVFHPPDLLQIRVLTDNPEDPEWSWIKWLPHVQHPTDTDAAGPTRMV MAV_4390|M.avium_104 CQLAVLHAPDRVGIAAVVGDGDRAHWDWLKWLPHNRHPTHDDALGPMRMV MUL_0860|M.ulcerans_Agy99 CQMAVLHGPDQLLVAAVVSDRNRPGWEWLKWLPHNQHPSHHDEVGAERMV MAB_3756c|M.abscessus_ATCC_199 CQLAMFHGPDQFLVAAVVNRHAAPHWDWLKWLPHSQHPSAFDGVGTSRLV *::*::* ** . : .:. . * *:***** :* : * *. *:: Mb3900|M.bovis_AF2122/97 FTRQEGLSDLAARGPHAPDSLPGGPYVVVVDLTG-----------GKAGF Rv3870|M.tuberculosis_H37Rv FTRQEGLSDLAARGPHAPDSLPGGPYVVVVDLTG-----------GKAGF MMAR_5445|M.marinum_M STRPDGLADLAARGPHAPDTLPTGPYVVVLDLTG-----------GKAGF MLBr_00053|M.leprae_Br4923 FTRSDSLADLMSRGPHAPDSLPGGPYVILVDLTG-----------GKAGF Mflv_0771|M.gilvum_PYR-GCK FTRTDGLSDLAARGPHTADATPSGPYVVVIDLTG-----------GRAGF Mvan_0074|M.vanbaalenii_PYR-1 FTRPDALSDLAARGPHTADAAPSGPYVVVIDLTG-----------GRAGF MSMEG_0061|M.smegmatis_MC2_155 YTRPDGLSDLTARGPHTADAAPGGPYVVVVDLTG-----------GKAGF TH_4195|M.thermoresistible__bu FTRPDGLSDLAARGPHTADSAPSGPYVVVVDLTG-----------GKAGF MAV_4390|M.avium_104 YSTAAQAQQALAG--LPVARLVLVAERAVAPI------------------ MUL_0860|M.ulcerans_Agy99 YPNITQASAAFDAVALPVMVIVDTDEHGKQLP------------------ MAB_3756c|M.abscessus_ATCC_199 YHSLGEVEESLASLITERERFSRTAQPSPDRPQILIVVDSGTLIGSERLI Mb3900|M.bovis_AF2122/97 PPDGRAGVTVITLGNHRGSAYRIRVHE-DGTADDRLP-NQSFRQVTSVTD Rv3870|M.tuberculosis_H37Rv PPDGRAGVTVITLGNHRGSAYRIRVHE-DGTADDRLP-NQSFRQVTSVTD MMAR_5445|M.marinum_M PPDGRAGVTVITLGNHRGSAYRIRVAE-NGTADDRLP-GQQFRLVTAAAD MLBr_00053|M.leprae_Br4923 PPDGRAGVTVITLGNHRSSTYRIRVNK-NGTADDRLP-GQSFRQVTSTVD Mflv_0771|M.gilvum_PYR-GCK PMDGRSGVTVLTLGNHR-STYRIRVDAGDGTADDKLP-GASFRLVASEVD Mvan_0074|M.vanbaalenii_PYR-1 PMDGRSGVTVITLGNHR-SAYRIRVDA-DGTADDKLP-GASFRLVASQVD MSMEG_0061|M.smegmatis_MC2_155 PPDGRAGVTVITLGAQRQAAYKLKVEK-DGKAEDRLP-NQPWREVTRVAD TH_4195|M.thermoresistible__bu PVDGRAGVTVLTLGNHRGSNYRIRVAA-DGTADDRLP-GQSFRLVTSVAD MAV_4390|M.avium_104 -----AGATVIAIGAGDD------GAPVTIRT-------AAGTVSPSRPD MUL_0860|M.ulcerans_Agy99 -----AGVTVLEVGRGPD------GTQVVVKR-------AGETTTLTRPD MAB_3756c|M.abscessus_ATCC_199 VDHGIDSVTLVEIGTRVDPLAARRGMQLELTERGLGAKGNVGSEVFAHPD ..*:: :* * Mb3900|M.bovis_AF2122/97 RMSPQQASRIARKLAGWSITGTILDKTSRVQKKVATDWHQLVGAQSVEEI Rv3870|M.tuberculosis_H37Rv RMSPQQASRIARKLAGWSITGTILDKTSRVQKKVATDWHQLVGAQSVEEI MMAR_5445|M.marinum_M SMTPQEATRLARKLAGWSITGTILDKTQRIQKKVATEFHQLVNAKSVEDI MLBr_00053|M.leprae_Br4923 HLSKAEATRIARKLAGWSITGTILDKTSRVQKKVATEWHQLVGANTVEEV Mflv_0771|M.gilvum_PYR-GCK RMSPAQAERLARKLAGWSITGTIIDKGTRVQKKVATEWHEIVGAQSVEEV Mvan_0074|M.vanbaalenii_PYR-1 GMTPRQAERVARKLAGWSITGTIIDKGTRVQKKVATEWHEIVGAQSVEEV MSMEG_0061|M.smegmatis_MC2_155 RMTPGQAGRIARKLAGWSITGTIIDKNVRVQKKVSNEWHHLVGAQSVEEV TH_4195|M.thermoresistible__bu RMTPEQAGHVARKLAGWSITGTIIDKNVRVQKKVATEWHQLVGAQSVEEV MAV_4390|M.avium_104 RMTAADALTCARRLAGQRV--TAGDG--------DGGWPGLVGLADVSGF MUL_0860|M.ulcerans_Agy99 ELDQVSALVCARLLAPHRCGDRAGGH--------PGDWARMLGIGEIATY MAB_3756c|M.abscessus_ATCC_199 HLTITEAMACARRLAPYRVLTGSGDEVQ-IQTEVSTRWSDIVGIGDPGLL : .* ** ** . : ::. Mb3900|M.bovis_AF2122/97 TPSRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGAGPHGMLIG Rv3870|M.tuberculosis_H37Rv TPSRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGAGPHGMLIG MMAR_5445|M.marinum_M TPGRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGGGPHGMLIG MLBr_00053|M.leprae_Br4923 LPSRWRMYTDNDRDRLKIPFGHEFKTGNIMYLDIKEGAEFGGGPHGMLIG Mflv_0771|M.gilvum_PYR-GCK TPARWRMFTDTDRDRLRIPFGHELKTGDVMYLDIKEGAEFGAGPHGMLIG Mvan_0074|M.vanbaalenii_PYR-1 TPARWRMFTDTDRDRLRIPFGHELKTGDVMYLDIKEGAEFGAGPHGMLIG MSMEG_0061|M.smegmatis_MC2_155 TPARWRMYADTDRDRLKIPFGHELKTGEIMYLDIKEGAEFGAGPHGMLIG TH_4195|M.thermoresistible__bu TPARWRMFADTDRDRLRIPFGHELKTGEIMYLDIKEGAEFGAGPHGMLIG MAV_4390|M.avium_104 DPATLWGRQ-TGRDRLRAPLGVAAD-GTPVELDIKEPAEHGMGPHGLCVG MUL_0860|M.ulcerans_Agy99 HPVSHWHKR-NQRERLCVPIGATAD-GSPVLLDIKEPAARGMGPHGLCIG MAB_3756c|M.abscessus_ATCC_199 NPEVVWRNR-VGRDRLRVPIGIAVD-GTPMELDIKEAAENGMGPHGLCIG * *:** *:* . * : ***** * * ****: :* Mb3900|M.bovis_AF2122/97 TTGSGKSEFLRTLILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAA Rv3870|M.tuberculosis_H37Rv TTGSGKSEFLRTLILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAA MMAR_5445|M.marinum_M TTGSGKSEFLRTMILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAA MLBr_00053|M.leprae_Br4923 TTGSGKSEFLRTLILSLVAMTHPNQVNLLLTDFKGGSTFLGMEKLPHTAA Mflv_0771|M.gilvum_PYR-GCK TTGSGKSEFLRTLILSLAATHHPDQINLLLTDFKGGSTFLGMEKLPHTAA Mvan_0074|M.vanbaalenii_PYR-1 TTGSGKSEFLRTLILSLAATHHPDQINLLLTDFKGGSTFLGMEKLPHTAA MSMEG_0061|M.smegmatis_MC2_155 TTGSGKSEFLRTLILSLVATHHPDQINLLLTDFKGGSTFLGMEKLPHTAA TH_4195|M.thermoresistible__bu TTGSGKSEFLRTLILSLAATHHPDQVNLLLTDFKGGSTFLGMEKLPHTAA MAV_4390|M.avium_104 ATGSGKSELLRTIALGMMARNSPDVLNLLLVDFKGGATFLDYANAPHVAA MUL_0860|M.ulcerans_Agy99 ATGSGKSELLRTVALGMMVGNSPEVLNLLLIDFKGGATFLDLEKAPHVAA MAB_3756c|M.abscessus_ATCC_199 ATGSGKSEFLRTLTLGMIATHSPDALNLVLVDFKGGATFLGLDRAQHVAA :*******:***: *.: . *: :**:* *****:***. . *.** Mb3900|M.bovis_AF2122/97 VVTNMAEEAELVSRMGEVLTGELDRRQSILRQAGMKVGAAGALSGVAEYE Rv3870|M.tuberculosis_H37Rv VVTNMAEEAELVSRMGEVLTGELDRRQSILRQAGMKVGAAGALSGVAEYE MMAR_5445|M.marinum_M VITNMAEEAELVSRMGEVLTGELDRRQSILRQAGMKVGAAGALSGVAEYE MLBr_00053|M.leprae_Br4923 VVTNMAEEAELVSRMGEVLTGELDRRQNILRQAGTLVGAAGALSGVAEYE Mflv_0771|M.gilvum_PYR-GCK VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGIQVGAAGALSGVAEYE Mvan_0074|M.vanbaalenii_PYR-1 VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGMQVGAAGALSGVAEYE MSMEG_0061|M.smegmatis_MC2_155 VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGMQVGAAGALSGVAEYE TH_4195|M.thermoresistible__bu VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGMQVGAAGALSGVAEYE MAV_4390|M.avium_104 VITNLADDAPLVARMRAALAGEMNRRQEALR-------TAG-CDSVAAYQ MUL_0860|M.ulcerans_Agy99 VITNLADQAPLVARMGEALAGEMNRRQHLLR-------TAGNFVSVAAYE MAB_3756c|M.abscessus_ATCC_199 IITNLAEEANLVSRMKDALAGEMNRRQELLR-------AAGNFANVTEYE ::**: ::* **:** .*:**::*** ** :** .*: *: Mb3900|M.bovis_AF2122/97 KYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL Rv3870|M.tuberculosis_H37Rv KYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL MMAR_5445|M.marinum_M KYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL MLBr_00053|M.leprae_Br4923 KYRERGANLAPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL Mflv_0771|M.gilvum_PYR-GCK KHRERGADLPPLPTLFVVVDEFAELLQNHPDFIGLFDRICRVGRSLRVHL Mvan_0074|M.vanbaalenii_PYR-1 KHRERGADLAPLPTLFVVVDEFAELLQNHPDFIQLFDRICRVGRSLRVHL MSMEG_0061|M.smegmatis_MC2_155 KHRERGADLPPLPTLFVVVDEFAELLQNHPDFINLFDRICRVGRSLRVHL TH_4195|M.thermoresistible__bu KYRERGADLPPLPTLFVVVDEFAELLQNHPDFINLFDRICRVGRSLRVHL MAV_4390|M.avium_104 HARRSAAALPALPTLFVIVDEFSELLSQQPDFADTFVAIGRLGRSLGIHL MUL_0860|M.ulcerans_Agy99 DARRRGAGLAALPTLFIIVDEFAELLSQHPDFAEVFVAIGRLGRSLGMHL MAB_3756c|M.abscessus_ATCC_199 RARAAGASLSPLPALFIIVDEFSELLSQHPDFAELFVAIGRLGRSLHVHL * .* *..**:**::****:***..:*** * * *:**** :** Mb3900|M.bovis_AF2122/97 LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNK Rv3870|M.tuberculosis_H37Rv LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNK MMAR_5445|M.marinum_M LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNK MLBr_00053|M.leprae_Br4923 LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK Mflv_0771|M.gilvum_PYR-GCK LLATQSLNTGGTRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK Mvan_0074|M.vanbaalenii_PYR-1 LLATQSLNTGGTRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK MSMEG_0061|M.smegmatis_MC2_155 LLATQSLNTGGVRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK TH_4195|M.thermoresistible__bu LLATQSLNTGGVRIDKLEPNLTYRIALRTTSSTESKAVIGTPEAQYITNK MAV_4390|M.avium_104 LLASQRLDEG--RLRGLDAHLSYRLCLKTLSEAESRAVLGNLDAYHLPT- MUL_0860|M.ulcerans_Agy99 LLASQRLEEG--RLRGLEAHLSYRVCLKTLSAIESRTALGTLDAFELPN- MAB_3756c|M.abscessus_ATCC_199 LLASQRLDEG--RLRGLESHLSYRLCLKTFSANESRAAIGVPDAYHLPN- ***:* *: * *: *:.:*:**:.*:* * **::.:* :* :.. Mb3900|M.bovis_AF2122/97 ESGVGFLRVGMEDPVKFSTFYISGPYMP---------------------- Rv3870|M.tuberculosis_H37Rv ESGVGFLRVGMEDPVKFSTFYISGPYMP---------------------- MMAR_5445|M.marinum_M ESGVGFLRVGMEDPIKFSTLYISGPYVP---------------------- MLBr_00053|M.leprae_Br4923 ESGVGFLRIGMEDPVKFSSLYTGIPFVP---------------------- Mflv_0771|M.gilvum_PYR-GCK ESGVGFLRVGMEDPVKFQSVYTGTPYVP---------------------- Mvan_0074|M.vanbaalenii_PYR-1 ESGVGFLRVGMEDPVKFQSVYTGNPYVP---------------------- MSMEG_0061|M.smegmatis_MC2_155 ESGVGFLRVGMEDPVKFRSVYTGNNYVP---------------------- TH_4195|M.thermoresistible__bu ESGVGFLRVGMEDPVKFRTVYTGNPYVP---------------------- MAV_4390|M.avium_104 DPGAGYLRVGAGAPIRFQAALVSGPLRPDTAPRP-------PAMVRVFGT MUL_0860|M.ulcerans_Agy99 TPGSGLLSSPTAELTRFETAFVSGPVPAGPPDADSVAL---PAAVRPFTS MAB_3756c|M.abscessus_ATCC_199 TPGSCYLKDDSGELTRFQTSYVSGPYVPYGPARRTVSSGGGGAAPRLFTA .* * :* : . . Mb3900|M.bovis_AF2122/97 -------------------------------------------------- Rv3870|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5445|M.marinum_M -------------------------------------------------- MLBr_00053|M.leprae_Br4923 -------------------------------------------------- Mflv_0771|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0074|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0061|M.smegmatis_MC2_155 -------------------------------------------------- TH_4195|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 RVVG------PVSR--PVEAAHPSGRSISAAVLDRLAGHGPAAHRVWLPP MUL_0860|M.ulcerans_Agy99 EATG------DVRTGGADGADTATGPTVLQTVLDRIAGHGPRAHQVWLPP MAB_3756c|M.abscessus_ATCC_199 APVALQMRPAEVVEDDSPAVSEATGRSVIDTILDRVEGHGNPAHEVWLPP Mb3900|M.bovis_AF2122/97 -------------------------------------------PAAGVET Rv3870|M.tuberculosis_H37Rv -------------------------------------------PAAGVET MMAR_5445|M.marinum_M -------------------------------------------PAT-AET MLBr_00053|M.leprae_Br4923 -------------------------------------------AIA-TET Mflv_0771|M.gilvum_PYR-GCK -------------------------------------------VTV---G Mvan_0074|M.vanbaalenii_PYR-1 -------------------------------------------TVG---N MSMEG_0061|M.smegmatis_MC2_155 -------------------------------------------AAP---E TH_4195|M.thermoresistible__bu -------------------------------------------HSS---A MAV_4390|M.avium_104 LGRPPELRTLLGG--------AADLTVPVGLVDRPFEQCRTPLIVDLSGA MUL_0860|M.ulcerans_Agy99 LDRAPALASLLSDGAAE----HAELAVPIGVVDRPFDQSRTPLTIDLTAA MAB_3756c|M.abscessus_ATCC_199 LDDSPTLGDLIPRHGRAGFDAVGSLTVPIGIVDRPYEQRRDPYIVDLSAA Mb3900|M.bovis_AF2122/97 NGEAGGPGQQTTRQAARIHRFTAAPVLEEAPTP----------------- Rv3870|M.tuberculosis_H37Rv NGEAGGPGQQTTRQAARIHRFTAAPVLEEAPTP----------------- MMAR_5445|M.marinum_M NGDGSGPSTQFAKRALQIREFTAAPVLEEALTP----------------- MLBr_00053|M.leprae_Br4923 NGDSSPSSPWASRKKVHIYEFTAAPILESTTTS----------------- Mflv_0771|M.gilvum_PYR-GCK AGD-DDTPRAHADSGIRIHRFTTAPIADTRVTV----------------- Mvan_0074|M.vanbaalenii_PYR-1 AGD-DEAPKAHADKNIRIHRFTTAPIMDARLG------------------ MSMEG_0061|M.smegmatis_MC2_155 SSDREAKPKAQRQSQVRIHQFTTTPIFDTAVS------------------ TH_4195|M.thermoresistible__bu SENGEARPRVPERQRVRIREFTCAPIPEAMVN------------------ MAV_4390|M.avium_104 AGNVAVVGAPRSGKSTALRTLITALAATHDPARVQFYCLDFGGGALSSLH MUL_0860|M.ulcerans_Agy99 AGNVAVVGAPQSGKSTTLSTLITALAATHDPDLVQFYCLDFGGGALAAVR MAB_3756c|M.abscessus_ATCC_199 AGNVAIVGAPQSGKSMAVRTLVTSLAVTHSPAQVQFYCLDFGGGTLTSLA : : : : Mb3900|M.bovis_AF2122/97 -------------------------------------------------- Rv3870|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5445|M.marinum_M -------------------------------------------------- MLBr_00053|M.leprae_Br4923 -------------------------------------------------- Mflv_0771|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0074|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0061|M.smegmatis_MC2_155 -------------------------------------------------- TH_4195|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 TLPHVGAVAGRAEPRRVGRIVAECEAVVGRREAFFGEHAIASIADYRQRR MUL_0860|M.ulcerans_Agy99 DLPHVGAVAGRGEPDLIRGIVAELESCLRTRESLFGEQGIDSIAAYRRLR MAB_3756c|M.abscessus_ATCC_199 QLPHVGSVASRLESDLIRRTFAEMLTIVRSRENAFRAYGIDSMAEYRRRK Mb3900|M.bovis_AF2122/97 -------------------------------------------------- Rv3870|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5445|M.marinum_M -------------------------------------------------- MLBr_00053|M.leprae_Br4923 -------------------------------------------------- Mflv_0771|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0074|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0061|M.smegmatis_MC2_155 -------------------------------------------------- TH_4195|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 ----PGS--DPFGDVFLVIDGWAVLRRDFETLEASIIALAGQGLSFGVHL MUL_0860|M.ulcerans_Agy99 ----ADSGAQRLADLFVVIDGWATLCHEFEELQEPITALAGQGLSYGLHV MAB_3756c|M.abscessus_ATCC_199 GAGDPQLANDPFGDVFFIIDGWSTVRQEFEALEPQVTALAAQGLGFGVHT Mb3900|M.bovis_AF2122/97 -------------------------------------------------- Rv3870|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5445|M.marinum_M -------------------------------------------------- MLBr_00053|M.leprae_Br4923 -------------------------------------------------- Mflv_0771|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0074|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0061|M.smegmatis_MC2_155 -------------------------------------------------- TH_4195|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 VLSASRWADIRPALRDQIGTRIELRLGDPADSEIDRRAAAHVPRDSPGRG MUL_0860|M.ulcerans_Agy99 VVSATRWAHLRGSLKDQLGTRIELRLGDPADSEVDRRGARQVPRDRPGRG MAB_3756c|M.abscessus_ATCC_199 VVTASRWAEIRPALKDQIGTRVELRLGDPLDSDFDRKLAQLVPDGRPGRG Mb3900|M.bovis_AF2122/97 -------------------------------------------------- Rv3870|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5445|M.marinum_M -------------------------------------------------- MLBr_00053|M.leprae_Br4923 -------------------------------------------------- Mflv_0771|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0074|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0061|M.smegmatis_MC2_155 -------------------------------------------------- TH_4195|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 LSHDGLHMVIASP-VADVAAG------------------ESVAPPIPLLP MUL_0860|M.ulcerans_Agy99 LCDDGMHMMIALPNVAEVVVSQ--------------QHAGSGAPAVPLLP MAB_3756c|M.abscessus_ATCC_199 ITRDRRHMLIGLPRVDSISSNQDLGEAIAAAAASMRQRSSVEAPQVRMLP Mb3900|M.bovis_AF2122/97 -------------------------------------------------- Rv3870|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5445|M.marinum_M -------------------------------------------------- MLBr_00053|M.leprae_Br4923 -------------------------------------------------- Mflv_0771|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0074|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0061|M.smegmatis_MC2_155 -------------------------------------------------- TH_4195|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 ARVDLDAVRRGS--GDEFAGRPLLGLQERQLQPLAIDFARESHLLILGAN MUL_0860|M.ulcerans_Agy99 QRVEHRDVVEAA--GAALSGRILLGLQQRRLQPVAVDFEHHAHLLILGDN MAB_3756c|M.abscessus_ATCC_199 HKIDYAALVPQAPQNDQPNLRILVGINESELAPTFLEFGEQPHMMIFGDS Mb3900|M.bovis_AF2122/97 -------------------------------------------------- Rv3870|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5445|M.marinum_M -------------------------------------------------- MLBr_00053|M.leprae_Br4923 -------------------------------------------------- Mflv_0771|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0074|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0061|M.smegmatis_MC2_155 -------------------------------------------------- TH_4195|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 GCGKTAALRTLCRELVRTNTAAQAQLVIVDFRRALLGIVESEQLRGYAMS MUL_0860|M.ulcerans_Agy99 ACGKSSALRTLCREITRTKTAAQARLFLVDFRRELLGLSESEYLGGHAIA MAB_3756c|M.abscessus_ATCC_199 ECGKTALLRTMCREIVRTTTPQQAQLFIVDYRRTLLGVVETEHLAKYAMS Mb3900|M.bovis_AF2122/97 -------------------------------------------------- Rv3870|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5445|M.marinum_M -------------------------------------------------- MLBr_00053|M.leprae_Br4923 -------------------------------------------------- Mflv_0771|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0074|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0061|M.smegmatis_MC2_155 -------------------------------------------------- TH_4195|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 PAALTALLPGLLDLLSGRMPPPDASQAQLRAGSWWSGPDVYVVVDDYDLV MUL_0860|M.ulcerans_Agy99 AGGLGAFLPGLVELLRARMPAPHLSQARLRDRSWWSGPGIYLMVDDYDLE MAB_3756c|M.abscessus_ATCC_199 SNTLVDEVPALIELLKSRMPGPDVTQQELRDRSWWSGPEIYILVDDYDLV Mb3900|M.bovis_AF2122/97 -------------------------------------------------- Rv3870|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5445|M.marinum_M -------------------------------------------------- MLBr_00053|M.leprae_Br4923 -------------------------------------------------- Mflv_0771|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0074|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0061|M.smegmatis_MC2_155 -------------------------------------------------- TH_4195|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 ASPSGNLLAPLVEFLPYASELGLHLIIARRSGGAERAMFEPLLAGLRDLG MUL_0860|M.ulcerans_Agy99 CTSASNPLLALLEYLPYATDLGLHLIVASRSGGATRALFEPLLAALRDFG MAB_3756c|M.abscessus_ATCC_199 ALASGNPLLPLAEYLPHSKDIGLHVVIARRTSGASRAMFEPMMARMKDLS Mb3900|M.bovis_AF2122/97 ------------------------------------------------- Rv3870|M.tuberculosis_H37Rv ------------------------------------------------- MMAR_5445|M.marinum_M ------------------------------------------------- MLBr_00053|M.leprae_Br4923 ------------------------------------------------- Mflv_0771|M.gilvum_PYR-GCK ------------------------------------------------- Mvan_0074|M.vanbaalenii_PYR-1 ------------------------------------------------- MSMEG_0061|M.smegmatis_MC2_155 ------------------------------------------------- TH_4195|M.thermoresistible__bu ------------------------------------------------- MAV_4390|M.avium_104 CMSLTMS----EAAPFAAAP--PLPPGRGVLTTRAGADELVQVAWSPP- MUL_0860|M.ulcerans_Agy99 CMALMMSGRCDEGPLFGSGRPMPLPPGRAVLVTWAGDERLVQVAWTEPG MAB_3756c|M.abscessus_ATCC_199 CIGLQMSGNKDEGVLLGTVRPSEQPPGRGTLVMRSGGQQLIQVAWSEPQ