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M. vanbaalenii PYR-1 Mvan_0074 (-)

annotation: cell divisionFtsK/SpoIIIE
coordinates: 83922 - 86144
length: 740

MTTRKFTPIIKRGPRLTPGEINVTPPEDLGVDIPPSGMQKALPWVMGGCMLGMIAILIFGGMRNFSPYML
MMPMMVVMGAVGMMAGGGSGGKKVPEINADRKEYLRYLAGLRTRVTSSASAQVTFFNYHGPHPDDLLSII
GTHRQWSRPANHDFYAATRIGLGSEPAVDRLLKPAVGSELAGPAGAPQPHLEPVSHMWVTKFLRTHGLIH
DCPKLVQLKTFPTIAVGGDSAGSAALLAAMICHLAVFHPPDMLQMRVLTDDPEDPAWAWLKWLPHLQHET
DTDAAGTTRMVFTRPDALSDLAARGPHTADAAPSGPYVVVIDLTGGRAGFPMDGRSGVTVITLGNHRSAY
RIRVDADGTADDKLPGASFRLVASQVDGMTPRQAERVARKLAGWSITGTIIDKGTRVQKKVATEWHEIVG
AQSVEEVTPARWRMFTDTDRDRLRIPFGHELKTGDVMYLDIKEGAEFGAGPHGMLIGTTGSGKSEFLRTL
ILSLAATHHPDQINLLLTDFKGGSTFLGMEKLPHTAAVVTNMEEEAELVSRMGEVLTGELDRRQSILRQA
GMQVGAAGALSGVAEYEKHRERGADLAPLPTLFVVVDEFAELLQNHPDFIQLFDRICRVGRSLRVHLLLA
TQSLNTGGTRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNKESGVGFLRVGMEDPVKFQSVYTG
NPYVPTVGNAGDDEAPKAHADKNIRIHRFTTAPIMDARLG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_0074--100% (740)cell divisionFtsK/SpoIIIE
M. vanbaalenii PYR-1Mvan_0413-e-10134.41% (715) cell divisionFtsK/SpoIIIE
M. vanbaalenii PYR-1Mvan_2393-3e-1726.13% (287) cell divisionFtsK/SpoIIIE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3900-0.079.78% (742) hypothetical protein Mb3900
M. gilvum PYR-GCKMflv_0771-0.093.51% (740) cell divisionFtsK/SpoIIIE
M. tuberculosis H37RvRv3870-0.079.78% (742) transmembrane protein
M. leprae Br4923MLBr_00053-0.077.33% (741) hypothetical protein MLBr_00053
M. abscessus ATCC 19977MAB_3756c-1e-13438.55% (747) putative FtsK/SpoIIIE family protein
M. marinum MMMAR_5445-0.078.09% (744) hypothetical protein MMAR_5445
M. avium 104MAV_4390-1e-10336.29% (711) ftsk/SpoIIIE family protein
M. smegmatis MC2 155MSMEG_0061-0.083.47% (738) ftsk/SpoIIIE family protein
M. thermoresistible (build 8)TH_4195-0.086.33% (739) PUTATIVE cell divisionFtsK/SpoIIIE
M. ulcerans Agy99MUL_0860-1e-10636.78% (734) hypothetical protein MUL_0860

CLUSTAL 2.0.9 multiple sequence alignment


Mb3900|M.bovis_AF2122/97            MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAM
Rv3870|M.tuberculosis_H37Rv         MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAM
MMAR_5445|M.marinum_M               MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAM
MLBr_00053|M.leprae_Br4923          MTTKKFTPTITRGPRLTPGEINITPPDDLGLEIPPSGIQKILPYVMVGCI
Mvan_0074|M.vanbaalenii_PYR-1       MTTRKFTPIIKRGPRLTPGEINVTPPEDLGVDIPPSGMQKALPWVMGGCM
Mflv_0771|M.gilvum_PYR-GCK          MTTRKFTPIIKRGPRLTPGEINVAPPEDLGVDIPPSGMQKALPWVMGGCM
MSMEG_0061|M.smegmatis_MC2_155      MTTKKFTPTIKRGPRLTPGEINVAPPDDLGIDIPPSGMQKALPWVMGGCM
TH_4195|M.thermoresistible__bu      MTTRKFTPTIKRGPRLTPGEINVTPPEDLGVEIPPSGVQKALPWVMGGCM
MAV_4390|M.avium_104                ---------------MTQADIVVEAPPELPAPESTGLPARLLPVALSVAG
MUL_0860|M.ulcerans_Agy99           ----------------MTEDLVVAAPPELAQTTSTGPLLRLVPLAMSIAT
MAB_3756c|M.abscessus_ATCC_199      ---------------MPGGEVNVQPPPEIPRPVPSPIIAKIMPLVMVVAM
                                                       :: : .* ::    ..    : :* .:  . 

Mb3900|M.bovis_AF2122/97            LGMIAIMVAGG--------TRQLSPYMLMMPLMMIVMMVGGLAGSTGGGG
Rv3870|M.tuberculosis_H37Rv         LGMIAIMVAGG--------TRQLSPYMLMMPLMMIVMMVGGLAGSTGGGG
MMAR_5445|M.marinum_M               LGMIVIMVAGG--------TRQLSPYMLMMPLMMIVMMVGTLAGGSGGGS
MLBr_00053|M.leprae_Br4923          VGMIAIMVLGG--------TKQLSPYMLMMPIMMVMMMAGGSGG--GGGG
Mvan_0074|M.vanbaalenii_PYR-1       LGMIAILIFGG--------MRNFSPYMLMMPMMVVMGAVGMMAGG-GSGG
Mflv_0771|M.gilvum_PYR-GCK          LGMIAILIFGG--------LRNFSPYMLMMPMMVVMGAVGMMASG-GSGG
MSMEG_0061|M.smegmatis_MC2_155      LGMIAIMVFTG--------VRQLSPYMLMMPLMMIMGTVGFMAGG-GSGG
TH_4195|M.thermoresistible__bu      LGMIAIMVFTG--------IRNLSPYMLMMPLMMVMATVGFMAGG-GPGG
MAV_4390|M.avium_104                IGVMTVVFASG-------GAAARQPAFLAFPATMLVSTVAAALIG-RSR-
MUL_0860|M.ulcerans_Agy99           LIAMAATYVSG-------APSARNPTMLVLPATMSLSLMVMAVSA-RGR-
MAB_3756c|M.abscessus_ATCC_199      VGMIAFFVTSGSFGGGAGGGMMRSPMFMLFPIMMMVSMVSMVSNS-GGKG
                                    :  :.     *            .* :: :*  : :              

Mb3900|M.bovis_AF2122/97            KKVPEINADRKEYLRYLAGLRTRVTSSATSQVAFFSYHAPHPEDLLSIVG
Rv3870|M.tuberculosis_H37Rv         KKVPEINADRKEYLRYLAGLRTRVTSSATSQVAFFSYHAPHPEDLLSIVG
MMAR_5445|M.marinum_M               KKVPEINADRKEYLRYLAGLRGRVTTSATSQVSFFGYHAPHPDDLLSIVG
MLBr_00053|M.leprae_Br4923          KKVPEINADRKEYLRYLAGLRARVTSSAASQVAFFSYHAPHPQDLLSIVG
Mvan_0074|M.vanbaalenii_PYR-1       KKVPEINADRKEYLRYLAGLRTRVTSSASAQVTFFNYHGPHPDDLLSIIG
Mflv_0771|M.gilvum_PYR-GCK          KKVPEINADRKEYLRYLAGLRTRVTSSAAAQVSFFNYHAPHPDDLLSIVG
MSMEG_0061|M.smegmatis_MC2_155      KKVPEINADRKEYLRYLAGLRTRVTSSASAQVAFFAYHAPHPDDLLSIIG
TH_4195|M.thermoresistible__bu      KRVPEINADRKEYLRYLAGLRNRVTSSAAAQVTFFAYHAPHPDDLLSIVG
MAV_4390|M.avium_104                RGGGGLDADRGRYLEYLNQLGRSVSEIAAAQCASALRDHPDPDTLWTLIG
MUL_0860|M.ulcerans_Agy99           RRGAGLDQDRVGYLQYLSELRQRVTEIAAAQRISSNRTHPEPDTVWTLIG
MAB_3756c|M.abscessus_ATCC_199      AKTSEINEDRKDYLRYLEVVRKNVTDTGAAQRKALLWNNPDPSALWTLAG
                                         :: **  **.**  :   *:  .::*        *.*. : :: *

Mb3900|M.bovis_AF2122/97            TQRQWSRPANADFYAATRIGIGDQPAVDRLLKPAVGGELAAASAAPQPFL
Rv3870|M.tuberculosis_H37Rv         TQRQWSRPANADFYAATRIGIGDQPAVDRLLKPAVGGELAAASAAPQPFL
MMAR_5445|M.marinum_M               TQRQWSRPANSDFYAAARIGIGDQPAVDRLLKPAVGGELAASSAAPQPYL
MLBr_00053|M.leprae_Br4923          TQRQWSRPANADFYAATRIGVGDQPAVDRLLKPAVGGELTASGAAPQPFL
Mvan_0074|M.vanbaalenii_PYR-1       THRQWSRPANHDFYAATRIGLGSEPAVDRLLKPAVGSELAGPAGAPQPHL
Mflv_0771|M.gilvum_PYR-GCK          THRQWSRAANHDFYAATRIGLGSEPAVDRLLKPAVGAELAGPAGAPQPHL
MSMEG_0061|M.smegmatis_MC2_155      THRQWARQANSEFFAATRIGIGAEIAVDRLLKPNTSGELAGGQAAPAPHL
TH_4195|M.thermoresistible__bu      THRQWSRQTNADFYAAVRIGIGSEPAVDRLLKPSVGAELVGPQGAPQPHL
MAV_4390|M.avium_104                GPRMWRRRPTGPDFCVVRVGMGVLPLARRVVAPPVP---------AEEVR
MUL_0860|M.ulcerans_Agy99           GSRMWERRPADADFCRIRIGLGTQPLATRLVAAPLP---------PPHRS
MAB_3756c|M.abscessus_ATCC_199      GRRMWERRPGDSDYCHVRVGTGDQRLAAQLVAPEIG---------PVEEL
                                      * * * .    :.  *:* *    . ::: .            .    

Mb3900|M.bovis_AF2122/97            EPVSHMWVVKFLRTHGLIHDCPKLLQLRTFPTIAIGGDLAGAAGLMTAMI
Rv3870|M.tuberculosis_H37Rv         EPVSHMWVVKFLRTHGLIHDCPKLLQLRTFPTIAIGGDLAGAAGLMTAMI
MMAR_5445|M.marinum_M               EPVSHMWVVKFLRTHGLIHDCPKLVQLRSFPTIAIGGDRPGADRLLTAMI
MLBr_00053|M.leprae_Br4923          EPVSHMWVVKFLRTHGLVHDCPKLLQMRTFPTIAVGGDTAGAGGLLTAMI
Mvan_0074|M.vanbaalenii_PYR-1       EPVSHMWVTKFLRTHGLIHDCPKLVQLKTFPTIAVGGDSAGSAALLAAMI
Mflv_0771|M.gilvum_PYR-GCK          EPVSHMWVTKFLRTHGLIHDCPKLLQLRTFPTIAVGGDTDGAVGLLTAMI
MSMEG_0061|M.smegmatis_MC2_155      EPVSHMWVTKFLRTHGLIHDCPKLVQLRTFPTVAVGGDPEAAEGLLTSMI
TH_4195|M.thermoresistible__bu      EPVSHMWVTKFLRTHGLIHDCPKLVQLRTFPTIAIGGDPEGAARLLTAMI
MAV_4390|M.avium_104                DPVTATALRRFLHTHATVPG-PVTVDLGAGSPVTIDGDAGAARAVLRAVV
MUL_0860|M.ulcerans_Agy99           DPVTVSALRRFLEAHARVTDVPIAIALHGAGVVTIGGDPARVRALLRAMV
MAB_3756c|M.abscessus_ATCC_199      EPVASVALRRFVRTHSLVPELPIALNLRGFAAVTIDGSPEVARGMLRAMI
                                    :**:   : :*:.:*. :   *  : :     :::.*.      :: :::

Mb3900|M.bovis_AF2122/97            CHLAVFHPPDLLQIRVLTEEPDDPDWSWLKWLPHVQHQTETDAAGSTRLI
Rv3870|M.tuberculosis_H37Rv         CHLAVFHPPDLLQIRVLTEEPDDPDWSWLKWLPHVQHQTETDAAGSTRLI
MMAR_5445|M.marinum_M               CHLAVFHPPDLLQIRVLTEDPEDPDWSWLKWLPHVQHQTETDGAGPVRMI
MLBr_00053|M.leprae_Br4923          CHLAVFHPPDLLQIRVLTEKPDDPNWSWLKWLPHIQHPTETDAAGAARMI
Mvan_0074|M.vanbaalenii_PYR-1       CHLAVFHPPDMLQMRVLTDDPEDPAWAWLKWLPHLQHETDTDAAGTTRMV
Mflv_0771|M.gilvum_PYR-GCK          CHLAVFHPPDMLQMRVLTDNPEDPVWAWLKWLPHLQHQTDTDAAGATRMV
MSMEG_0061|M.smegmatis_MC2_155      CHLAVFHPPDLVQIRVLTDNPEDPKWSWLKWLPHTQHQTDTDAAGPTRLV
TH_4195|M.thermoresistible__bu      CHLAVFHPPDLLQIRVLTDNPEDPEWSWIKWLPHVQHPTDTDAAGPTRMV
MAV_4390|M.avium_104                CQLAVLHAPDRVGIAAVVGDGDRAHWDWLKWLPHNRHPTHDDALGPMRMV
MUL_0860|M.ulcerans_Agy99           CQMAVLHGPDQLLVAAVVSDRNRPGWEWLKWLPHNQHPSHHDEVGAERMV
MAB_3756c|M.abscessus_ATCC_199      CQLAMFHGPDQFLVAAVVNRHAAPHWDWLKWLPHSQHPSAFDGVGTSRLV
                                    *::*::* ** . : .:.     . * *:***** :* :  *  *. *::

Mb3900|M.bovis_AF2122/97            FTRQEGLSDLAARGPHAPDSLPGGPYVVVVDLTG-----------GKAGF
Rv3870|M.tuberculosis_H37Rv         FTRQEGLSDLAARGPHAPDSLPGGPYVVVVDLTG-----------GKAGF
MMAR_5445|M.marinum_M               STRPDGLADLAARGPHAPDTLPTGPYVVVLDLTG-----------GKAGF
MLBr_00053|M.leprae_Br4923          FTRSDSLADLMSRGPHAPDSLPGGPYVILVDLTG-----------GKAGF
Mvan_0074|M.vanbaalenii_PYR-1       FTRPDALSDLAARGPHTADAAPSGPYVVVIDLTG-----------GRAGF
Mflv_0771|M.gilvum_PYR-GCK          FTRTDGLSDLAARGPHTADATPSGPYVVVIDLTG-----------GRAGF
MSMEG_0061|M.smegmatis_MC2_155      YTRPDGLSDLTARGPHTADAAPGGPYVVVVDLTG-----------GKAGF
TH_4195|M.thermoresistible__bu      FTRPDGLSDLAARGPHTADSAPSGPYVVVVDLTG-----------GKAGF
MAV_4390|M.avium_104                YSTAAQAQQALAG--LPVARLVLVAERAVAPI------------------
MUL_0860|M.ulcerans_Agy99           YPNITQASAAFDAVALPVMVIVDTDEHGKQLP------------------
MAB_3756c|M.abscessus_ATCC_199      YHSLGEVEESLASLITERERFSRTAQPSPDRPQILIVVDSGTLIGSERLI
                                                                                      

Mb3900|M.bovis_AF2122/97            PPDGRAGVTVITLGNHRGSAYRIRVHE-DGTADDRLP-NQSFRQVTSVTD
Rv3870|M.tuberculosis_H37Rv         PPDGRAGVTVITLGNHRGSAYRIRVHE-DGTADDRLP-NQSFRQVTSVTD
MMAR_5445|M.marinum_M               PPDGRAGVTVITLGNHRGSAYRIRVAE-NGTADDRLP-GQQFRLVTAAAD
MLBr_00053|M.leprae_Br4923          PPDGRAGVTVITLGNHRSSTYRIRVNK-NGTADDRLP-GQSFRQVTSTVD
Mvan_0074|M.vanbaalenii_PYR-1       PMDGRSGVTVITLGNHR-SAYRIRVDA-DGTADDKLP-GASFRLVASQVD
Mflv_0771|M.gilvum_PYR-GCK          PMDGRSGVTVLTLGNHR-STYRIRVDAGDGTADDKLP-GASFRLVASEVD
MSMEG_0061|M.smegmatis_MC2_155      PPDGRAGVTVITLGAQRQAAYKLKVEK-DGKAEDRLP-NQPWREVTRVAD
TH_4195|M.thermoresistible__bu      PVDGRAGVTVLTLGNHRGSNYRIRVAA-DGTADDRLP-GQSFRLVTSVAD
MAV_4390|M.avium_104                -----AGATVIAIGAGDD------GAPVTIRT-------AAGTVSPSRPD
MUL_0860|M.ulcerans_Agy99           -----AGVTVLEVGRGPD------GTQVVVKR-------AGETTTLTRPD
MAB_3756c|M.abscessus_ATCC_199      VDHGIDSVTLVEIGTRVDPLAARRGMQLELTERGLGAKGNVGSEVFAHPD
                                          ..*:: :*                                   *

Mb3900|M.bovis_AF2122/97            RMSPQQASRIARKLAGWSITGTILDKTSRVQKKVATDWHQLVGAQSVEEI
Rv3870|M.tuberculosis_H37Rv         RMSPQQASRIARKLAGWSITGTILDKTSRVQKKVATDWHQLVGAQSVEEI
MMAR_5445|M.marinum_M               SMTPQEATRLARKLAGWSITGTILDKTQRIQKKVATEFHQLVNAKSVEDI
MLBr_00053|M.leprae_Br4923          HLSKAEATRIARKLAGWSITGTILDKTSRVQKKVATEWHQLVGANTVEEV
Mvan_0074|M.vanbaalenii_PYR-1       GMTPRQAERVARKLAGWSITGTIIDKGTRVQKKVATEWHEIVGAQSVEEV
Mflv_0771|M.gilvum_PYR-GCK          RMSPAQAERLARKLAGWSITGTIIDKGTRVQKKVATEWHEIVGAQSVEEV
MSMEG_0061|M.smegmatis_MC2_155      RMTPGQAGRIARKLAGWSITGTIIDKNVRVQKKVSNEWHHLVGAQSVEEV
TH_4195|M.thermoresistible__bu      RMTPEQAGHVARKLAGWSITGTIIDKNVRVQKKVATEWHQLVGAQSVEEV
MAV_4390|M.avium_104                RMTAADALTCARRLAGQRV--TAGDG--------DGGWPGLVGLADVSGF
MUL_0860|M.ulcerans_Agy99           ELDQVSALVCARLLAPHRCGDRAGGH--------PGDWARMLGIGEIATY
MAB_3756c|M.abscessus_ATCC_199      HLTITEAMACARRLAPYRVLTGSGDEVQ-IQTEVSTRWSDIVGIGDPGLL
                                     :   .*   ** **         .            :  ::.       

Mb3900|M.bovis_AF2122/97            TPSRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGAGPHGMLIG
Rv3870|M.tuberculosis_H37Rv         TPSRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGAGPHGMLIG
MMAR_5445|M.marinum_M               TPGRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGGGPHGMLIG
MLBr_00053|M.leprae_Br4923          LPSRWRMYTDNDRDRLKIPFGHEFKTGNIMYLDIKEGAEFGGGPHGMLIG
Mvan_0074|M.vanbaalenii_PYR-1       TPARWRMFTDTDRDRLRIPFGHELKTGDVMYLDIKEGAEFGAGPHGMLIG
Mflv_0771|M.gilvum_PYR-GCK          TPARWRMFTDTDRDRLRIPFGHELKTGDVMYLDIKEGAEFGAGPHGMLIG
MSMEG_0061|M.smegmatis_MC2_155      TPARWRMYADTDRDRLKIPFGHELKTGEIMYLDIKEGAEFGAGPHGMLIG
TH_4195|M.thermoresistible__bu      TPARWRMFADTDRDRLRIPFGHELKTGEIMYLDIKEGAEFGAGPHGMLIG
MAV_4390|M.avium_104                DPATLWGRQ-TGRDRLRAPLGVAAD-GTPVELDIKEPAEHGMGPHGLCVG
MUL_0860|M.ulcerans_Agy99           HPVSHWHKR-NQRERLCVPIGATAD-GSPVLLDIKEPAARGMGPHGLCIG
MAB_3756c|M.abscessus_ATCC_199      NPEVVWRNR-VGRDRLRVPIGIAVD-GTPMELDIKEAAENGMGPHGLCIG
                                     *          *:**  *:*   . *  : ***** *  * ****: :*

Mb3900|M.bovis_AF2122/97            TTGSGKSEFLRTLILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAA
Rv3870|M.tuberculosis_H37Rv         TTGSGKSEFLRTLILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAA
MMAR_5445|M.marinum_M               TTGSGKSEFLRTMILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAA
MLBr_00053|M.leprae_Br4923          TTGSGKSEFLRTLILSLVAMTHPNQVNLLLTDFKGGSTFLGMEKLPHTAA
Mvan_0074|M.vanbaalenii_PYR-1       TTGSGKSEFLRTLILSLAATHHPDQINLLLTDFKGGSTFLGMEKLPHTAA
Mflv_0771|M.gilvum_PYR-GCK          TTGSGKSEFLRTLILSLAATHHPDQINLLLTDFKGGSTFLGMEKLPHTAA
MSMEG_0061|M.smegmatis_MC2_155      TTGSGKSEFLRTLILSLVATHHPDQINLLLTDFKGGSTFLGMEKLPHTAA
TH_4195|M.thermoresistible__bu      TTGSGKSEFLRTLILSLAATHHPDQVNLLLTDFKGGSTFLGMEKLPHTAA
MAV_4390|M.avium_104                ATGSGKSELLRTIALGMMARNSPDVLNLLLVDFKGGATFLDYANAPHVAA
MUL_0860|M.ulcerans_Agy99           ATGSGKSELLRTVALGMMVGNSPEVLNLLLIDFKGGATFLDLEKAPHVAA
MAB_3756c|M.abscessus_ATCC_199      ATGSGKSEFLRTLTLGMIATHSPDALNLVLVDFKGGATFLGLDRAQHVAA
                                    :*******:***: *.: .   *: :**:* *****:***.  .  *.**

Mb3900|M.bovis_AF2122/97            VVTNMAEEAELVSRMGEVLTGELDRRQSILRQAGMKVGAAGALSGVAEYE
Rv3870|M.tuberculosis_H37Rv         VVTNMAEEAELVSRMGEVLTGELDRRQSILRQAGMKVGAAGALSGVAEYE
MMAR_5445|M.marinum_M               VITNMAEEAELVSRMGEVLTGELDRRQSILRQAGMKVGAAGALSGVAEYE
MLBr_00053|M.leprae_Br4923          VVTNMAEEAELVSRMGEVLTGELDRRQNILRQAGTLVGAAGALSGVAEYE
Mvan_0074|M.vanbaalenii_PYR-1       VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGMQVGAAGALSGVAEYE
Mflv_0771|M.gilvum_PYR-GCK          VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGIQVGAAGALSGVAEYE
MSMEG_0061|M.smegmatis_MC2_155      VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGMQVGAAGALSGVAEYE
TH_4195|M.thermoresistible__bu      VVTNMEEEAELVSRMGEVLTGELDRRQSILRQAGMQVGAAGALSGVAEYE
MAV_4390|M.avium_104                VITNLADDAPLVARMRAALAGEMNRRQEALR-------TAG-CDSVAAYQ
MUL_0860|M.ulcerans_Agy99           VITNLADQAPLVARMGEALAGEMNRRQHLLR-------TAGNFVSVAAYE
MAB_3756c|M.abscessus_ATCC_199      IITNLAEEANLVSRMKDALAGEMNRRQELLR-------AAGNFANVTEYE
                                    ::**: ::* **:**  .*:**::***  **       :**   .*: *:

Mb3900|M.bovis_AF2122/97            KYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL
Rv3870|M.tuberculosis_H37Rv         KYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL
MMAR_5445|M.marinum_M               KYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL
MLBr_00053|M.leprae_Br4923          KYRERGANLAPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHL
Mvan_0074|M.vanbaalenii_PYR-1       KHRERGADLAPLPTLFVVVDEFAELLQNHPDFIQLFDRICRVGRSLRVHL
Mflv_0771|M.gilvum_PYR-GCK          KHRERGADLPPLPTLFVVVDEFAELLQNHPDFIGLFDRICRVGRSLRVHL
MSMEG_0061|M.smegmatis_MC2_155      KHRERGADLPPLPTLFVVVDEFAELLQNHPDFINLFDRICRVGRSLRVHL
TH_4195|M.thermoresistible__bu      KYRERGADLPPLPTLFVVVDEFAELLQNHPDFINLFDRICRVGRSLRVHL
MAV_4390|M.avium_104                HARRSAAALPALPTLFVIVDEFSELLSQQPDFADTFVAIGRLGRSLGIHL
MUL_0860|M.ulcerans_Agy99           DARRRGAGLAALPTLFIIVDEFAELLSQHPDFAEVFVAIGRLGRSLGMHL
MAB_3756c|M.abscessus_ATCC_199      RARAAGASLSPLPALFIIVDEFSELLSQHPDFAELFVAIGRLGRSLHVHL
                                      *  .* *..**:**::****:***..:***   *  * *:**** :**

Mb3900|M.bovis_AF2122/97            LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNK
Rv3870|M.tuberculosis_H37Rv         LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNK
MMAR_5445|M.marinum_M               LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNK
MLBr_00053|M.leprae_Br4923          LLATQSLQTGGVRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK
Mvan_0074|M.vanbaalenii_PYR-1       LLATQSLNTGGTRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK
Mflv_0771|M.gilvum_PYR-GCK          LLATQSLNTGGTRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK
MSMEG_0061|M.smegmatis_MC2_155      LLATQSLNTGGVRIDKLEPNLTYRIALRTTSSAESKAVIGTPEAQYITNK
TH_4195|M.thermoresistible__bu      LLATQSLNTGGVRIDKLEPNLTYRIALRTTSSTESKAVIGTPEAQYITNK
MAV_4390|M.avium_104                LLASQRLDEG--RLRGLDAHLSYRLCLKTLSEAESRAVLGNLDAYHLPT-
MUL_0860|M.ulcerans_Agy99           LLASQRLEEG--RLRGLEAHLSYRVCLKTLSAIESRTALGTLDAFELPN-
MAB_3756c|M.abscessus_ATCC_199      LLASQRLDEG--RLRGLESHLSYRLCLKTFSANESRAAIGVPDAYHLPN-
                                    ***:* *: *  *:  *:.:*:**:.*:* *  **::.:*  :*  :.. 

Mb3900|M.bovis_AF2122/97            ESGVGFLRVGMEDPVKFSTFYISGPYMP----------------------
Rv3870|M.tuberculosis_H37Rv         ESGVGFLRVGMEDPVKFSTFYISGPYMP----------------------
MMAR_5445|M.marinum_M               ESGVGFLRVGMEDPIKFSTLYISGPYVP----------------------
MLBr_00053|M.leprae_Br4923          ESGVGFLRIGMEDPVKFSSLYTGIPFVP----------------------
Mvan_0074|M.vanbaalenii_PYR-1       ESGVGFLRVGMEDPVKFQSVYTGNPYVP----------------------
Mflv_0771|M.gilvum_PYR-GCK          ESGVGFLRVGMEDPVKFQSVYTGTPYVP----------------------
MSMEG_0061|M.smegmatis_MC2_155      ESGVGFLRVGMEDPVKFRSVYTGNNYVP----------------------
TH_4195|M.thermoresistible__bu      ESGVGFLRVGMEDPVKFRTVYTGNPYVP----------------------
MAV_4390|M.avium_104                DPGAGYLRVGAGAPIRFQAALVSGPLRPDTAPRP-------PAMVRVFGT
MUL_0860|M.ulcerans_Agy99           TPGSGLLSSPTAELTRFETAFVSGPVPAGPPDADSVAL---PAAVRPFTS
MAB_3756c|M.abscessus_ATCC_199      TPGSCYLKDDSGELTRFQTSYVSGPYVPYGPARRTVSSGGGGAAPRLFTA
                                     .*   *        :* :   .    .                      

Mb3900|M.bovis_AF2122/97            --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
MAV_4390|M.avium_104                RVVG------PVSR--PVEAAHPSGRSISAAVLDRLAGHGPAAHRVWLPP
MUL_0860|M.ulcerans_Agy99           EATG------DVRTGGADGADTATGPTVLQTVLDRIAGHGPRAHQVWLPP
MAB_3756c|M.abscessus_ATCC_199      APVALQMRPAEVVEDDSPAVSEATGRSVIDTILDRVEGHGNPAHEVWLPP
                                                                                      

Mb3900|M.bovis_AF2122/97            -------------------------------------------PAAGVET
Rv3870|M.tuberculosis_H37Rv         -------------------------------------------PAAGVET
MMAR_5445|M.marinum_M               -------------------------------------------PAT-AET
MLBr_00053|M.leprae_Br4923          -------------------------------------------AIA-TET
Mvan_0074|M.vanbaalenii_PYR-1       -------------------------------------------TVG---N
Mflv_0771|M.gilvum_PYR-GCK          -------------------------------------------VTV---G
MSMEG_0061|M.smegmatis_MC2_155      -------------------------------------------AAP---E
TH_4195|M.thermoresistible__bu      -------------------------------------------HSS---A
MAV_4390|M.avium_104                LGRPPELRTLLGG--------AADLTVPVGLVDRPFEQCRTPLIVDLSGA
MUL_0860|M.ulcerans_Agy99           LDRAPALASLLSDGAAE----HAELAVPIGVVDRPFDQSRTPLTIDLTAA
MAB_3756c|M.abscessus_ATCC_199      LDDSPTLGDLIPRHGRAGFDAVGSLTVPIGIVDRPYEQRRDPYIVDLSAA
                                                                                      

Mb3900|M.bovis_AF2122/97            NGEAGGPGQQTTRQAARIHRFTAAPVLEEAPTP-----------------
Rv3870|M.tuberculosis_H37Rv         NGEAGGPGQQTTRQAARIHRFTAAPVLEEAPTP-----------------
MMAR_5445|M.marinum_M               NGDGSGPSTQFAKRALQIREFTAAPVLEEALTP-----------------
MLBr_00053|M.leprae_Br4923          NGDSSPSSPWASRKKVHIYEFTAAPILESTTTS-----------------
Mvan_0074|M.vanbaalenii_PYR-1       AGD-DEAPKAHADKNIRIHRFTTAPIMDARLG------------------
Mflv_0771|M.gilvum_PYR-GCK          AGD-DDTPRAHADSGIRIHRFTTAPIADTRVTV-----------------
MSMEG_0061|M.smegmatis_MC2_155      SSDREAKPKAQRQSQVRIHQFTTTPIFDTAVS------------------
TH_4195|M.thermoresistible__bu      SENGEARPRVPERQRVRIREFTCAPIPEAMVN------------------
MAV_4390|M.avium_104                AGNVAVVGAPRSGKSTALRTLITALAATHDPARVQFYCLDFGGGALSSLH
MUL_0860|M.ulcerans_Agy99           AGNVAVVGAPQSGKSTTLSTLITALAATHDPDLVQFYCLDFGGGALAAVR
MAB_3756c|M.abscessus_ATCC_199      AGNVAIVGAPQSGKSMAVRTLVTSLAVTHSPAQVQFYCLDFGGGTLTSLA
                                      :              :  :  :                          

Mb3900|M.bovis_AF2122/97            --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
MAV_4390|M.avium_104                TLPHVGAVAGRAEPRRVGRIVAECEAVVGRREAFFGEHAIASIADYRQRR
MUL_0860|M.ulcerans_Agy99           DLPHVGAVAGRGEPDLIRGIVAELESCLRTRESLFGEQGIDSIAAYRRLR
MAB_3756c|M.abscessus_ATCC_199      QLPHVGSVASRLESDLIRRTFAEMLTIVRSRENAFRAYGIDSMAEYRRRK
                                                                                      

Mb3900|M.bovis_AF2122/97            --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
MAV_4390|M.avium_104                ----PGS--DPFGDVFLVIDGWAVLRRDFETLEASIIALAGQGLSFGVHL
MUL_0860|M.ulcerans_Agy99           ----ADSGAQRLADLFVVIDGWATLCHEFEELQEPITALAGQGLSYGLHV
MAB_3756c|M.abscessus_ATCC_199      GAGDPQLANDPFGDVFFIIDGWSTVRQEFEALEPQVTALAAQGLGFGVHT
                                                                                      

Mb3900|M.bovis_AF2122/97            --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
MAV_4390|M.avium_104                VLSASRWADIRPALRDQIGTRIELRLGDPADSEIDRRAAAHVPRDSPGRG
MUL_0860|M.ulcerans_Agy99           VVSATRWAHLRGSLKDQLGTRIELRLGDPADSEVDRRGARQVPRDRPGRG
MAB_3756c|M.abscessus_ATCC_199      VVTASRWAEIRPALKDQIGTRVELRLGDPLDSDFDRKLAQLVPDGRPGRG
                                                                                      

Mb3900|M.bovis_AF2122/97            --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
MAV_4390|M.avium_104                LSHDGLHMVIASP-VADVAAG------------------ESVAPPIPLLP
MUL_0860|M.ulcerans_Agy99           LCDDGMHMMIALPNVAEVVVSQ--------------QHAGSGAPAVPLLP
MAB_3756c|M.abscessus_ATCC_199      ITRDRRHMLIGLPRVDSISSNQDLGEAIAAAAASMRQRSSVEAPQVRMLP
                                                                                      

Mb3900|M.bovis_AF2122/97            --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
MAV_4390|M.avium_104                ARVDLDAVRRGS--GDEFAGRPLLGLQERQLQPLAIDFARESHLLILGAN
MUL_0860|M.ulcerans_Agy99           QRVEHRDVVEAA--GAALSGRILLGLQQRRLQPVAVDFEHHAHLLILGDN
MAB_3756c|M.abscessus_ATCC_199      HKIDYAALVPQAPQNDQPNLRILVGINESELAPTFLEFGEQPHMMIFGDS
                                                                                      

Mb3900|M.bovis_AF2122/97            --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
MAV_4390|M.avium_104                GCGKTAALRTLCRELVRTNTAAQAQLVIVDFRRALLGIVESEQLRGYAMS
MUL_0860|M.ulcerans_Agy99           ACGKSSALRTLCREITRTKTAAQARLFLVDFRRELLGLSESEYLGGHAIA
MAB_3756c|M.abscessus_ATCC_199      ECGKTALLRTMCREIVRTTTPQQAQLFIVDYRRTLLGVVETEHLAKYAMS
                                                                                      

Mb3900|M.bovis_AF2122/97            --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
MAV_4390|M.avium_104                PAALTALLPGLLDLLSGRMPPPDASQAQLRAGSWWSGPDVYVVVDDYDLV
MUL_0860|M.ulcerans_Agy99           AGGLGAFLPGLVELLRARMPAPHLSQARLRDRSWWSGPGIYLMVDDYDLE
MAB_3756c|M.abscessus_ATCC_199      SNTLVDEVPALIELLKSRMPGPDVTQQELRDRSWWSGPEIYILVDDYDLV
                                                                                      

Mb3900|M.bovis_AF2122/97            --------------------------------------------------
Rv3870|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_5445|M.marinum_M               --------------------------------------------------
MLBr_00053|M.leprae_Br4923          --------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      --------------------------------------------------
TH_4195|M.thermoresistible__bu      --------------------------------------------------
MAV_4390|M.avium_104                ASPSGNLLAPLVEFLPYASELGLHLIIARRSGGAERAMFEPLLAGLRDLG
MUL_0860|M.ulcerans_Agy99           CTSASNPLLALLEYLPYATDLGLHLIVASRSGGATRALFEPLLAALRDFG
MAB_3756c|M.abscessus_ATCC_199      ALASGNPLLPLAEYLPHSKDIGLHVVIARRTSGASRAMFEPMMARMKDLS
                                                                                      

Mb3900|M.bovis_AF2122/97            -------------------------------------------------
Rv3870|M.tuberculosis_H37Rv         -------------------------------------------------
MMAR_5445|M.marinum_M               -------------------------------------------------
MLBr_00053|M.leprae_Br4923          -------------------------------------------------
Mvan_0074|M.vanbaalenii_PYR-1       -------------------------------------------------
Mflv_0771|M.gilvum_PYR-GCK          -------------------------------------------------
MSMEG_0061|M.smegmatis_MC2_155      -------------------------------------------------
TH_4195|M.thermoresistible__bu      -------------------------------------------------
MAV_4390|M.avium_104                CMSLTMS----EAAPFAAAP--PLPPGRGVLTTRAGADELVQVAWSPP-
MUL_0860|M.ulcerans_Agy99           CMALMMSGRCDEGPLFGSGRPMPLPPGRAVLVTWAGDERLVQVAWTEPG
MAB_3756c|M.abscessus_ATCC_199      CIGLQMSGNKDEGVLLGTVRPSEQPPGRGTLVMRSGGQQLIQVAWSEPQ