For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
LLNAPTQALLGRPLVGNGANGAPGTGANGGDGGILFGSGGAGGSGAAGMAGGNGGAAGLFGNGGAGGAGG SATAGAAGAGGNGGAGGLLFGTAGAGGNGGLSLGLGVAGGAGGAGGSGGSDTAGHGGTGGAGGLLFGAGE DGTTPGGNGGAGGVAGLFGDGGNGGNAGVGTPAGNVGAGGTGGLLLGQDGMTGLT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3653 | PE_PGRS61 | - | 100% (195) | PE-PGRS FAMILY-RELATED PROTEIN |
| M. tuberculosis H37Rv | Rv1818c | PE_PGRS33 | 7e-68 | 56.57% (251) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv2741 | PE_PGRS47 | 1e-65 | 64.10% (195) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3677 | PE_PGRS61 | 1e-107 | 82.28% (237) | PE-PGRS family-related protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 9e-41 | 51.96% (179) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01556 | infB | 1e-07 | 39.53% (86) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 6e-25 | 42.94% (177) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_0478 | - | 9e-64 | 55.37% (242) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 9e-21 | 43.12% (160) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-41 | 52.02% (198) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_4332 | - | 2e-25 | 35.27% (275) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1339 | - | 8e-61 | 58.82% (221) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 3e-41 | 54.10% (183) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3653|M.tuberculosis_H37Rv --------------------------------------------------
Mb3677|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0478|M.marinum_M --------------------------------------------------
MUL_1339|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Rv3653|M.tuberculosis_H37Rv --------------------------------------------------
Mb3677|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0478|M.marinum_M --------------------------------------------------
MUL_1339|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Rv3653|M.tuberculosis_H37Rv --------------------------------------------------
Mb3677|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0478|M.marinum_M --------------------------------------------------
MUL_1339|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 -----------------------------------------MAGKARVHE
Rv3653|M.tuberculosis_H37Rv --------------------------------------------------
Mb3677|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0478|M.marinum_M ---------------------------------------MSFVSVIPEQL
MUL_1339|M.ulcerans_Agy99 ---------------------------------------MSYVIAAPEEF
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------MSIIDFILNLF
MAV_4827|M.avium_104 ---------------------------------------MNIVLGVSMAP
MLBr_01556|M.leprae_Br4923 LAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRESFGGIKPAAD
Rv3653|M.tuberculosis_H37Rv --------------------------------------------------
Mb3677|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0478|M.marinum_M T------------------------AAATN----------LAGVGSTIST
MUL_1339|M.ulcerans_Agy99 A------------------------SAARN----------LANIGVTINA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 R------------------------DPVEAASYVADPEAALANAGLSAVS
MAV_4827|M.avium_104 S--------------------------SIQMVVLEGEYADGATVEEDAID
MLBr_01556|M.leprae_Br4923 KG-----------------------AEQVATKAQAKRLGESLDQTLDRAL
Rv3653|M.tuberculosis_H37Rv --------------------------------------------------
Mb3677|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0478|M.marinum_M AN-------------ATAAGPTAAALAAGADDVSAAVSSFFGAYARDYQA
MUL_1339|M.ulcerans_Agy99 AN-------------ANAILATTEVIQPGADAVSAAITALINSHGLGYQS
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_4332|M.thermoresistible__bu ---------MPFITSGAAFVGGAAMLLAGPGGVSALEAAGSAPRTVEYEY
MAB_4284c|M.abscessus_ATCC_199 AAQVGAVMPVVAESVASNYGYQSQWVNTGN-PIHDLSGNLQNYYAAQPDG
MAV_4827|M.avium_104 VTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAAL
MLBr_01556|M.leprae_Br4923 DKAVAGNGATTAAPVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQ
Rv3653|M.tuberculosis_H37Rv ----------------------------------------------MLNA
Mb3677|M.bovis_AF2122/97 ----------------------------------------------MLNA
MMAR_0478|M.marinum_M FSVQVEALHDQFVRAVTSGAASYAG--AEATSVQQI-------LLDAINA
MUL_1339|M.ulcerans_Agy99 ISQQTTAFHDRFVQTVNAAAASYTTTDLTAASLLKS-------MPTAVNA
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_4332|M.thermoresistible__bu SLVACDSTLPLMCEAGDSVGGLGGASHDRSAFSASALGMASFGPDWNPGG
MAB_4284c|M.abscessus_ATCC_199 PSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGP
MAV_4827|M.avium_104 RDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLA
MLBr_01556|M.leprae_Br4923 PGVPLPGQQGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQ
Rv3653|M.tuberculosis_H37Rv PTQALLG------RPLVGNGANGAPGTGANGGDGG-------------IL
Mb3677|M.bovis_AF2122/97 PTQALLG------RPLVGNGANGAPGTGANGGDGG-------------IL
MMAR_0478|M.marinum_M PTQALLG------RPLIGNGANAAPGSGANGGDGG-------------IL
MUL_1339|M.ulcerans_Agy99 PAQALFG------RPLIGNGSNGTPGTGAPGGDGG-------------IL
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_4332|M.thermoresistible__bu AFLGLIGPG----GLLIGDGLNGTDAYIDENG-----------------V
MAB_4284c|M.abscessus_ATCC_199 LLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIAS-------------G
MAV_4827|M.avium_104 VVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAG--------------L
MLBr_01556|M.leprae_Br4923 SVARPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRP------------PR
Rv3653|M.tuberculosis_H37Rv FGSGGAGGS---------------GAAGMAGGNG------GAAG------
Mb3677|M.bovis_AF2122/97 FGSGGAGGS---------------GAAGMAGGNG------GAAG------
MMAR_0478|M.marinum_M YGNGGAGGS---------------GAAGGNGGAG------GAAG------
MUL_1339|M.ulcerans_Agy99 FGSGGAGGS---------------GAGGQDGGAG------GRAG------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_4332|M.thermoresistible__bu FHEATRGGN-----------------GGLLWGNG----------------
MAB_4284c|M.abscessus_ATCC_199 QGSTAVNGDVRDSNIIN-------ADHGSNVGVDQSQTRVGGDYTN----
MAV_4827|M.avium_104 EKLESLPGG--------------LLLVGSGVDVAPLKQVLQTTT------
MLBr_01556|M.leprae_Br4923 TGVPRPGGGRPGAPVGG----RSDAGGGNYRGGGVGALPGGGSGGFRGRP
* * .
Rv3653|M.tuberculosis_H37Rv -LFGNGGAGGAGGS-ATAG-------------------------------
Mb3677|M.bovis_AF2122/97 -LFGNGGAGGAGGS-ATAG-------------------------------
MMAR_0478|M.marinum_M -LVGNGGAGGAGGN-NAAGGSGGAGGLL---------YGNGGAGGIGGT-
MUL_1339|M.ulcerans_Agy99 -LFGNGGAGGAGGTGQTQGGAGGAGGLF---------FGNGGAGGPGGSG
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGG-TGTGANGGAGGVG-----GVGGTGAAGAAGGAGGL
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGG-TGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTA
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGST-TAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGH
TH_4332|M.thermoresistible__bu ---GKGGNGLDAGLYTVPDPDNPGSTIQ---------------------M
MAB_4284c|M.abscessus_ATCC_199 -VSGHGSADIDKSVTVVDDHSQRNTTNIN------DSFNTDRSTNIGSGN
MAV_4827|M.avium_104 --FLDVSVAEEPETALARGAALAAANAP-----------LFASSTAALAY
MLBr_01556|M.leprae_Br4923 GGGGHGGGGRPGQRGGAAGAFGRPGGAPR---------RGRKSKRQKRQE
. .
Rv3653|M.tuberculosis_H37Rv --AAGAGGNGGAG----------------------GLLFGTAGAGGNGGL
Mb3677|M.bovis_AF2122/97 --AAGAGGNGGAG----------------------GLLFGTAGAGGNGGL
MMAR_0478|M.marinum_M --SAGSGGAGGAG----------------------GLLFGTGGAGGTGGF
MUL_1339|M.ulcerans_Agy99 GLNGGAGGAGGVG----------------------GLLFGAGGAGGAGGS
Mflv_5091|M.gilvum_PYR-GCK GETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGA
Mvan_1264|M.vanbaalenii_PYR-1 GETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGV
MSMEG_0868|M.smegmatis_MC2_155 STGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEI
TH_4332|M.thermoresistible__bu YFEASDGADGGRG----------------------GFLFGNGGDGGNGGN
MAB_4284c|M.abscessus_ATCC_199 TTNTEIGSHNQAN---------------------IGTSTSAGGSAAVGGN
MAV_4827|M.avium_104 AQDPGTGAVDQYS-------------------LPDYLYVPVDPEPGDDEL
MLBr_01556|M.leprae_Br4923 YDSMQAPVVGGVR-----------------LPHGNGETIRLARGASLSDF
. . .
Rv3653|M.tuberculosis_H37Rv S-------------------------------------------------
Mb3677|M.bovis_AF2122/97 S-------------------------------------------------
MMAR_0478|M.marinum_M G-------------------------------------------------
MUL_1339|M.ulcerans_Agy99 GT------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK G----------STGAVGG-------VGGKG----IQGGQG----------
Mvan_1264|M.vanbaalenii_PYR-1 G----------ATGGAGG-------VGGKG----IQGGQG----------
MSMEG_0868|M.smegmatis_MC2_155 YSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGT
TH_4332|M.thermoresistible__bu VG------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AG------------------------------------------------
MAV_4827|M.avium_104 AY------------------------------------------------
MLBr_01556|M.leprae_Br4923 AEKIDAN-------------------------------------PAALVQ
Rv3653|M.tuberculosis_H37Rv -----LGLGVAGGAG----------------------------------G
Mb3677|M.bovis_AF2122/97 -----LGLGVAGGAG----------------------------------G
MMAR_0478|M.marinum_M -----GGLMTSGGAGGTGGAGGLLF------------------------G
MUL_1339|M.ulcerans_Agy99 -----SGIGGLGGDGGSAGALSISAG-----------------------G
Mflv_5091|M.gilvum_PYR-GCK ---LQGGKGGDGGAGGKGGDADSMGS------------------AGATGG
Mvan_1264|M.vanbaalenii_PYR-1 ---LQGGQGGDGGTGGTGGDATSMGE------------------AGATGG
MSMEG_0868|M.smegmatis_MC2_155 AKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGA
TH_4332|M.thermoresistible__bu -----GKNGADPVTATVAADKSVAG------------------------G
MAB_4284c|M.abscessus_ATCC_199 ----LAGNAGLAGNAGLAGNAGLAGN----------------------AG
MAV_4827|M.avium_104 -----SAVGEEDAESPTVVIEKLFLP------------------------
MLBr_01556|M.leprae_Br4923 ALFNLGEMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLEPFDLT
Rv3653|M.tuberculosis_H37Rv AGGSGGSD-------------------------TAGHGGT----------
Mb3677|M.bovis_AF2122/97 AGGSGGSD-------------------------TAGHGGT----------
MMAR_0478|M.marinum_M TGGSGGAGGGS-------------------NAFTAGDGGA----------
MUL_1339|M.ulcerans_Agy99 AGGNGGTG-------------------------LSGFGGA----------
Mflv_5091|M.gilvum_PYR-GCK KGGNGGNGGRGGLFG---------------KGGNAGNGAD----------
Mvan_1264|M.vanbaalenii_PYR-1 KGGNGGNGGRGSLFG---------------RGGNAGNGGN----------
MSMEG_0868|M.smegmatis_MC2_155 VGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNG
TH_4332|M.thermoresistible__bu NGGNGGRGGLLFG--------------------LGGNGGN----------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAG------------------NAGLAGN----------
MAV_4827|M.avium_104 EDSEPRRRPVLLVG--------------------SGLAVVG---------
MLBr_01556|M.leprae_Br4923 YGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDTIRKANVR---------
. .
Rv3653|M.tuberculosis_H37Rv ------------GGAGG--LLFGAG-------------------------
Mb3677|M.bovis_AF2122/97 ------------GGAGG--LLFGAGG-AGGAGGLG---------------
MMAR_0478|M.marinum_M ------------GGAGG--LLFGTGG-SGGDGGLAP--------------
MUL_1339|M.ulcerans_Agy99 ------------GGAGGNAGLYGHGG-GGGAGGTGT--------------
Mflv_5091|M.gilvum_PYR-GCK ------------GGTGGAGGAGGTGG-TGGAGGTGG--------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------GGTGGNGGNGGTGG-TGGNGGTGG--------------
MSMEG_0868|M.smegmatis_MC2_155 PAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTG
TH_4332|M.thermoresistible__bu ------------GGWSTTSYLDARGG-NGGNGGLGG--------------
MAB_4284c|M.abscessus_ATCC_199 ------------AGLAGNAGLAGNAGLAGNAGLAGN--------------
MAV_4827|M.avium_104 -----------ISAVLALEIALAIGIRTTGTVALQP--------------
MLBr_01556|M.leprae_Br4923 --------EAEAGGITQHIGAYQVGVDLDGSERLITFIDTPG--------
.. .
Rv3653|M.tuberculosis_H37Rv --------------------------------------------------
Mb3677|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0478|M.marinum_M -------------GAMFGNGGHGGTGGAGGT---LSGIGGHGGAGGLGQ-
MUL_1339|M.ulcerans_Agy99 -------------GMGVDNDGIGGAGGAGGAGGWLIGTGGTGGTGGFGD-
Mflv_5091|M.gilvum_PYR-GCK ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
Mvan_1264|M.vanbaalenii_PYR-1 ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
MSMEG_0868|M.smegmatis_MC2_155 QTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGR
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------AGLAGNAGLAGNAGLAGN----AGLAGNAGLAGNAGL
MAV_4827|M.avium_104 ----------------TPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPV
MLBr_01556|M.leprae_Br4923 ---HEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIV
Rv3653|M.tuberculosis_H37Rv --------------------------------------------------
Mb3677|M.bovis_AF2122/97 ----------------------------GFRG----------AGGTGGAG
MMAR_0478|M.marinum_M -VSGGAGGDGGNGGVFFGGGGDGGIGGHGITG----------SGGSGGSG
MUL_1339|M.ulcerans_Agy99 -GPLGGQGGDGGNAGLFGVGGDGGLGGTGFFG----------AGGAGGAA
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNG
TH_4332|M.thermoresistible__bu -----VLRPGGLLSLLLPSGAASEPGGLFTGG----------NGGNGGLA
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAG----------NAAVAGNA
MAV_4827|M.avium_104 AAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIP---------AAPPVVPVP
MLBr_01556|M.leprae_Br4923 VAVNKIDKEGADPAKIRGQLTEYGLVAEDFGG------DTMFIDISAKVG
Rv3653|M.tuberculosis_H37Rv --------------------------------------------------
Mb3677|M.bovis_AF2122/97 GDG----------------------------GNAGLFGDGG---------
MMAR_0478|M.marinum_M GSGGFLP---------------------GGAGVAGLIGDGG---------
MUL_1339|M.ulcerans_Agy99 GNAGLISGTGDVGGQGGVGGFGEGGAG-GDGGGAGLIGNGG---------
Mflv_5091|M.gilvum_PYR-GCK GAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------
Mvan_1264|M.vanbaalenii_PYR-1 GAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---------
MSMEG_0868|M.smegmatis_MC2_155 GAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVI
TH_4332|M.thermoresistible__bu IAN----------------------------HWVGITDGVP---------
MAB_4284c|M.abscessus_ATCC_199 AVGGVLN-----------------------TGVSGAIGGSS---------
MAV_4827|M.avium_104 VVVPPVP-----------------VPVPVRIPVPDPVSPPQ---------
MLBr_01556|M.leprae_Br4923 TNIEALLEAVLLTADAALDLRANSGMEAQGVAIEAHLDRGR---------
Rv3653|M.tuberculosis_H37Rv --------------------------------------------------
Mb3677|M.bovis_AF2122/97 --------AG----------------------------------------
MMAR_0478|M.marinum_M --------AGGHGG---SGGSGGGTGG----------------------S
MUL_1339|M.ulcerans_Agy99 --------SGGTGGNAVGNSGVGGHGG----------------------A
Mflv_5091|M.gilvum_PYR-GCK --------TGGTGGQGG-LGGGGGTG-----------------------G
Mvan_1264|M.vanbaalenii_PYR-1 --------TGGTGGQGG-LGGVGGTG-----------------------G
MSMEG_0868|M.smegmatis_MC2_155 GSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDG
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------------------------L
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Rv3653|M.tuberculosis_H37Rv --------------------------------------------------
Mb3677|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0478|M.marinum_M GGSAGTLLGNGGAGGGGGSGSTT--------AGG-----GGSGGDAGALF
MUL_1339|M.ulcerans_Agy99 GGRGGRLYGNGGVGGNGGFSGPI--------TAGGAGGTGGTGGSAGLPG
Mflv_5091|M.gilvum_PYR-GCK QGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
MSMEG_0868|M.smegmatis_MC2_155 HGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGG
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HVGGAINESLGGSGSVGGSTAVG-------------------GGAHTGVG
MAV_4827|M.avium_104 LAPPRLSVPQPVQPPVRVPQPPS---------------PPQVGGTVPQSP
MLBr_01556|M.leprae_Br4923 -GPVATVLVQRGTLRIGDSVVAG----------------DAYGRVRRMVD
Rv3653|M.tuberculosis_H37Rv --------------------------------------------------
Mb3677|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0478|M.marinum_M GNGGAGGAGGSGAATGGSGGTGGSSALLFGTGGVGGVGGSGGDSGGTGGA
MUL_1339|M.ulcerans_Agy99 DGGAGGAGGASGFAGGGTGGIGGTGGLPFGAAGDGGNGGFGAGGRGGSGG
Mflv_5091|M.gilvum_PYR-GCK SGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGK
Mvan_1264|M.vanbaalenii_PYR-1 VGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGT
MSMEG_0868|M.smegmatis_MC2_155 DGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGST
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVG
MAV_4827|M.avium_104 PQHQTPPGEGTPPKPDGPGNYGGGHVPTPGAGGSGGSGGGHVPTPGAGGS
MLBr_01556|M.leprae_Br4923 EHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARK
Rv3653|M.tuberculosis_H37Rv ------------------EDGTTPGG------NGGAG-------------
Mb3677|M.bovis_AF2122/97 -----------GAGG-AGEDGTTPGG------NGGAG-------------
MMAR_0478|M.marinum_M GGQGGAMFGNGGAGG-GGGDGINVGG------KGGAGGAAATLFGSGGTG
MUL_1339|M.ulcerans_Agy99 AGGDAWLFGSGGSGGSGGAGAINDGG------SGGAVGNGGRLFGDAGAG
Mflv_5091|M.gilvum_PYR-GCK AGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGAT
Mvan_1264|M.vanbaalenii_PYR-1 AGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSA
MSMEG_0868|M.smegmatis_MC2_155 LGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDG
TH_4332|M.thermoresistible__bu -GPDDDAVSSSAYGGHGGHGAGPGSG------------------------
MAB_4284c|M.abscessus_ATCC_199 VGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVNTGVGVGSHVGGG
MAV_4827|M.avium_104 GGSGGGHVPTPGTGGPGGTGGSGGGHVP----TPGAGTPGGSGGGHLPFP
MLBr_01556|M.leprae_Br4923 RNALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQ
Rv3653|M.tuberculosis_H37Rv --------------------------------------------------
Mb3677|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0478|M.marinum_M GDGGNAGAGVTFGGAGGEGGAAALLGGNGGSGGHGGIG------------
MUL_1339|M.ulcerans_Agy99 GSGGAGGTSFLDTVIVSSNGGAAGNGGSAGLVGNGGAGGAGGQGGLIVSA
Mflv_5091|M.gilvum_PYR-GCK GAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
Mvan_1264|M.vanbaalenii_PYR-1 GSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
MSMEG_0868|M.smegmatis_MC2_155 GAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGW
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ISESLGGSGSVGG-------------------------------------
MAV_4827|M.avium_104 GAGSTPG-------------------------------------------
MLBr_01556|M.leprae_Br4923 VDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRAEGKATELASRE
Rv3653|M.tuberculosis_H37Rv ----------------------------------------GVAG------
Mb3677|M.bovis_AF2122/97 ----------------------------------------GVAG------
MMAR_0478|M.marinum_M --NVGGKGGAGAAGAMLLGNGGDGGDGGNSLAS-LAGA-GGAAGNAGLIG
MUL_1339|M.ulcerans_Agy99 DDNNGGAGGDGGGAGLLLGAGGAGGQGGLGGNT-VDGGNGGNGGNAALIG
Mflv_5091|M.gilvum_PYR-GCK AGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG------
Mvan_1264|M.vanbaalenii_PYR-1 AGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG------
MSMEG_0868|M.smegmatis_MC2_155 VQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWK
TH_4332|M.thermoresistible__bu ---------------------GNGGSAVANSLGNAIAGNGGDAG------
MAB_4284c|M.abscessus_ATCC_199 -------------------STAVGGGAHTSAINDALGGSGSVGGSTAVGG
MAV_4827|M.avium_104 --------------------GSGGGHLPTPGAGTPGGGLGGFGGG-----
MLBr_01556|M.leprae_Br4923 GVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRSSKVGI
.
Rv3653|M.tuberculosis_H37Rv -------------------------------LFGDGGNGGNAGVGTPAGN
Mb3677|M.bovis_AF2122/97 -------------------------------LFGDGGNGGNAGVGTPAGN
MMAR_0478|M.marinum_M SGGTGGAGGQSFSGTGGKGGDGGSAL-----LIGDGGNGGNGGTGATAGV
MUL_1339|M.ulcerans_Agy99 DGGSGGAGGDGGSGDAGDGGAGGDAR-----LVGSGGNGGNGGFSATPAA
Mflv_5091|M.gilvum_PYR-GCK -----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 -----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG
MSMEG_0868|M.smegmatis_MC2_155 SGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSG
TH_4332|M.thermoresistible__bu ----------------------------RFVLIGPGGNGGNGGTGLXXXP
MAB_4284c|M.abscessus_ATCC_199 GAHTSAINESMNSSINASHSSSMNES-----FGSSMGSHGAAGTGFEAQG
MAV_4827|M.avium_104 ------------------------------HAPAPGGGLGGGGGHAPAPG
MLBr_01556|M.leprae_Br4923 IAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFE
. .
Rv3653|M.tuberculosis_H37Rv ----VGAGGTGG--LLLGQDGMTGLT----
Mb3677|M.bovis_AF2122/97 ----VGAGGTGG--LLLGQDGMTGLT----
MMAR_0478|M.marinum_M ----GGTAGTGG--FLFGLDGMNGSP----
MUL_1339|M.ulcerans_Agy99 ----GGTGDAGG--AVFGSDGVAGLP----
Mflv_5091|M.gilvum_PYR-GCK --GAGGSGGSGGSGGSGGSGGAAGDSDD--
Mvan_1264|M.vanbaalenii_PYR-1 --GAGGSGGSGGSGGAGGSGGAAGDSD---
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGGNGGADGTPGTAGTTGANNP--
TH_4332|M.thermoresistible__bu ----RPRRRRNHRRTRRRPNGRRPRPPPGR
MAB_4284c|M.abscessus_ATCC_199 -----HAQGHASETAHTTLPGAEHH-----
MAV_4827|M.avium_104 ----GGLGGFGGGHSGGGLGGLGGGHK---
MLBr_01556|M.leprae_Br4923 CGMTLGYSDIKEGDVIESYELVEKQRA---