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M. tuberculosis H37Rv Rv3652 (PE_PGRS60)

annotation: PE-PGRS FAMILY-RELATED PROTEIN
coordinates: 4093632 - 4093946
length: 104

MSYVIAAPEALVAAATDLATLGSTIGAANAAAAGSTTALLTAGADEVSAAIAAYSECTARPIRHSVRGRR
RSMSGSCRPWPQVGAPMRPPRPPASRRCRARSIC
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3652PE_PGRS60-100% (104)PE-PGRS FAMILY-RELATED PROTEIN
M. tuberculosis H37RvRv0742PE_PGRS82e-1777.36% (53) PE-PGRS family protein
M. tuberculosis H37RvRv0278cPE_PGRS36e-1777.36% (53) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3676PE_PGRS601e-55100.00% (104) PE-PGRS family-related protein
M. gilvum PYR-GCK-----
M. leprae Br4923MLBr_01183-3e-0542.31% (52) hypothetical protein MLBr_01183
M. abscessus ATCC 19977-----
M. marinum MMMAR_0608-1e-1781.13% (53) PE-PGRS family protein
M. avium 104MAV_1346-3e-0956.60% (53) PE family protein
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0570-7e-1881.13% (53) PE_PGRS family protein
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_01183|M.leprae_Br4923       MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSI
MAV_1346|M.avium_104             MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAPAAADEVSA
Rv3652|M.tuberculosis_H37Rv      MS-YVIAAPEALVAAATDLATLGSTIGAANAAAAGSTTALLTAGADEVSA
Mb3676|M.bovis_AF2122/97         MS-YVIAAPEALVAAATDLATLGSTIGAANAAAAGSTTALLTAGADEVSA
MMAR_0608|M.marinum_M            MS-FVITAPEALTAAATDLASLGSTIGAANAAAVAPTTAVLAAGADEVSA
MUL_0570|M.ulcerans_Agy99        MS-FVITAPEALTAAATDLASLGSTIGAANAAAVAPTTAVLAAGADEVSA
                                 *. :: : *:** *.*. *  *.::  * ****.  ** : ...**:** 

MLBr_01183|M.leprae_Br4923       LLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETAN-----
MAV_1346|M.avium_104             LQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAANRVNTS
Rv3652|M.tuberculosis_H37Rv      AIAAYSECTARPIR-HSVRGR------RRSMSGSCRPWPQVGAPMRPP--
Mb3676|M.bovis_AF2122/97         AIAAYSECTARPIR-HSVRGR------RRSMSGSCRPWPQVGAPMRPP--
MMAR_0608|M.marinum_M            AVAALFDAQGQAYQLLSARAATFHEQFLQALSGGGASYAAAEAAAVSPLL
MUL_0570|M.ulcerans_Agy99        AVAAMFDAQGQAYQLLSARAAAFHEQFLQALSGGGASYAAGEAAAVSPLL
                                   *   .  .   :  : :.        : :  .  .:    :.      

MLBr_01183|M.leprae_Br4923       -------------------------------------------------H
MAV_1346|M.avium_104             AAALQGLAPNVIPNAAPAADP------------------------PPAGT
Rv3652|M.tuberculosis_H37Rv      ------------RP---------------------------------PAS
Mb3676|M.bovis_AF2122/97         ------------RP---------------------------------PAS
MMAR_0608|M.marinum_M            DAINAPVLAATGRPLIGNGANGAPGTGADGGAAGWLIGNGGAGGSGTPGT
MUL_0570|M.ulcerans_Agy99        DAINAPVLADTGRPLIGNGAN--------GGAAGWLIGNGGAGGSGTPGT
                                                                                   

MLBr_01183|M.leprae_Br4923       DSL-----------------------------------------------
MAV_1346|M.avium_104             TSLG-------------TSIGWAQNVGAAASDFITLGEGQFAPVPGAAGI
Rv3652|M.tuberculosis_H37Rv      RRCR-------------------------ARSIC----------------
Mb3676|M.bovis_AF2122/97         RRCR-------------------------ARSIC----------------
MMAR_0608|M.marinum_M            ASVAGGNGGNGGAGGLLFGTGGAGGAGGTASSLVGAIPGGNGGYGGDGGL
MUL_0570|M.ulcerans_Agy99        ASVAGGNGGNGGAGGLLFGTGGAGGAGGTASSLVGAIPGGNGGYGGDGGL
                                                                                   

MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             PNFNPGLTAATTAGPPAPAAPAAAAGAPVLASMGRGPSIG----------
Rv3652|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3676|M.bovis_AF2122/97         --------------------------------------------------
MMAR_0608|M.marinum_M            LFGRGGAGGAGGFGNNTTGGIGGLGGAGGLFGAGGDGGVGGFGTFAGNGG
MUL_0570|M.ulcerans_Agy99        LFGRGGAGGAGGFGNNTTGGIGGLGGAGGLFGAGGDGGVGGFGTFAGNGG
                                                                                   

MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
Rv3652|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3676|M.bovis_AF2122/97         --------------------------------------------------
MMAR_0608|M.marinum_M            DGGTGLFAAGGDGGAGGSGLTQGGDGGIGGAALGLFGAGGAGGTGGEGGL
MUL_0570|M.ulcerans_Agy99        DGGTGLFAAGGDSGAGG---------------------------------
                                                                                   

MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
Rv3652|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3676|M.bovis_AF2122/97         --------------------------------------------------
MMAR_0608|M.marinum_M            FGGAGGMGGSAGMLFGNGGDGGAGAAATIGNAAGNGGAGGNAGMLIGAGG
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
                                                                                   

MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             ------------------------------------GLSVPPSWAPGGVA
Rv3652|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3676|M.bovis_AF2122/97         --------------------------------------------------
MMAR_0608|M.marinum_M            AGGNGGFGFSASDGGAGGAGGNAGFLYGAGGAGGAGGDSVGGADGGDGGN
MUL_0570|M.ulcerans_Agy99        -------------------------------------DSVGGADGGDGGN
                                                                                   

MLBr_01183|M.leprae_Br4923       --------------------------------------------------
MAV_1346|M.avium_104             PAANATPAQLVGAGFTSAAPDTAPVTAVPGGVPSMATAGRGGYGLGAPRY
Rv3652|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3676|M.bovis_AF2122/97         --------------------------------------------------
MMAR_0608|M.marinum_M            GGKAGLVGQGGDGGAGGNNNSGFGTGGSGGKGGDAVLIGNGGNGGNAGSG
MUL_0570|M.ulcerans_Agy99        GGKAGLVGQGGDGGAGGNNNSGFGTGGSGGKGGDAVLIGNGGNGGNAGSG
                                                                                   

MLBr_01183|M.leprae_Br4923       ---------------------------
MAV_1346|M.avium_104             GVKPTVMPKPAI---------------
Rv3652|M.tuberculosis_H37Rv      ---------------------------
Mb3676|M.bovis_AF2122/97         ---------------------------
MMAR_0608|M.marinum_M            GVGPGIAGAAGIGGLLIGEDGMAGLTP
MUL_0570|M.ulcerans_Agy99        GVGPGIAGAAGIGGLLIGEDGMAGLTP