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M. tuberculosis H37Rv Rv3511 (PE_PGRS55)

annotation: PE-PGRS FAMILY PROTEIN
coordinates: 3939617 - 3941761
length: 714

VSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQVLAAGADEVSARIAALFGMYGLEYQAISAQVA
AYHQQFVQTLRTGAASYMLAEATNVEQNLLNLINAPTQTLLGRPLIGDGANATTPGGAGGDGGLLFGSGG
NGAPGAPGQAGGAGGSAGLLGNGGSGGAGGTGAPGGNGGNAGWLYGRGGVGGAGGIGGGTGGAGGHAWLF
GHGGTGGIGGGPGGNGGWLLGNGGHGGAGGIGGGSGGAGGNGGWLLGNGGIGGAGGTGGGAGGTGGNAAW
LLGGGGTGGAGGIGGGNGGHGGNGGWLLGNGGNGGLGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGA
GSTGTAGGGSGGTGGDGGTGGRGGLLMGAGAGGHGGTGGAGGAGVNGGGAGGAGGAGGNGGAGGQAALLF
GRGGTGGAGGYGGDGGGGGDGFDGTMAGLGGTGGSGGTGGDGGAPGNGGAGGAGQLLSHSGVAGASGKGG
AGGTGGNGGAGSAGADAPAGSGAMGSTGFAGGAGGDGGNGGGSGASQGNGGNGGNGGTGGKGGTGGAGMN
SLDPLLAAQDGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGG
AGGAGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAGAGGT
GFTPRRRRQRRQRR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3511PE_PGRS55-100% (714)PE-PGRS FAMILY PROTEIN
M. tuberculosis H37RvRv3508PE_PGRS540.059.21% (738) PE-PGRS family protein
M. tuberculosis H37RvRv3514PE_PGRS570.059.84% (732) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3541PE_PGRS550.099.43% (706) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-14249.43% (619) triple helix repeat-containing collagen
M. leprae Br4923MLBr_01183-1e-1135.87% (92) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-8e-4735.06% (445) hypothetical protein MAB_4284c
M. marinum MMMAR_4999-0.067.50% (760) PE-PGRS family protein
M. avium 104MAV_4827-1e-2441.80% (189) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-12040.72% (776) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-1e-4337.30% (370) PUTATIVE -
M. ulcerans Agy99MUL_4367-0.050.06% (781) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-14348.50% (633) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            --------------------------------------------------
MMAR_4999|M.marinum_M               --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         ---------------------------MSFVLISPEVVSAAAGDLANVGS
Mb3541|M.bovis_AF2122/97            ---------------------------MSFVLISPEVVSAAAGDLANVGS
MMAR_4999|M.marinum_M               ---------------------------MTYVVVSPEIVAAAAGTLTRISS
MUL_4367|M.ulcerans_Agy99           ---------------------------MSFVSVGPGLLEAAARDLAGLGA
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------MMFLAPPGGPGPISAAIQLTST
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------MSIIDFILNLFRDPVEAASYVADPEAAL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------------------MNIVLGVSMAPSSIQMVVLEGEY
                                                                                      

Rv3511|M.tuberculosis_H37Rv         TISAANKAAAAATTQVLAAGADEVSAR-----IAALFGMYGL--------
Mb3541|M.bovis_AF2122/97            TISAANKAAAAATTQVLAAGADEVSAR-----IAALFGMYGL--------
MMAR_4999|M.marinum_M               SVSAANAAAAASTTDLLAAGADEVSTR-----IAALFGVHGL--------
MUL_4367|M.ulcerans_Agy99           GLREANLAAAGATVGVLPAAGDEVSAA-----IAELFGGFGR--------
Mflv_5091|M.gilvum_PYR-GCK          ---------MVTFGGGATPTPTSLGAA-----AVDLSGTS----------
Mvan_1264|M.vanbaalenii_PYR-1       GSEATEPWYVVSFGGSGAPTPNNLAAS-----LVDLSGTS----------
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ANAGLSAVSAAQVGAVMPVVAESVASN-----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ADGATVEEDAIDVTGADDAATASAPDR-----------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         ---------------------EYQAISAQVAAYHQQFVQTLRTGAASYML
Mb3541|M.bovis_AF2122/97            ---------------------EYQAISAQVAAYHQQFVQTLRTGAASYML
MMAR_4999|M.marinum_M               ---------------------EYQHISAQAAAYHEQFIQAMQGGARSYAW
MUL_4367|M.ulcerans_Agy99           ---------------------EYQAMGARVALLHDDFVRALTAGGSAYGQ
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         AEATN---------------VEQNLLNLINAPTQTLLGRPLIGDGAN-AT
Mb3541|M.bovis_AF2122/97            AEATN---------------VEQNLLNLINAPTQTLLGRPLIGDGAN-AT
MMAR_4999|M.marinum_M               AEAAN---------------AEQNLLNLINSPTQAFFGRSLIGDGAN-AT
MUL_4367|M.ulcerans_Agy99           AEALNMWPLQ---------ELEQQALGVVNAPSMALFGRPSIGNGVDGVA
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------CGLICNGQD---
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------CGLICNGQD---
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGIN-GT
TH_3810|M.thermoresistible__bu      -----------------------------------------VD-------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------YGYQSQWVN---
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------------------------------VISAILGTREG---
                                                                                      

Rv3511|M.tuberculosis_H37Rv         TPGGAGGDGGLLFGSGGNGA-PGAPGQAGGAGGSAGLLGNGGSGGAGGTG
Mb3541|M.bovis_AF2122/97            TPGGAGGDGGLLFGSGGNGA-PGAPGQAGGAGGSAGLLGNGGSGGAGGTG
MMAR_4999|M.marinum_M               TPGGAGGDGGLLIGNGGNGA-AGAAGQAGGAGGSGGLLGNGGNGGAGGIG
MUL_4367|M.ulcerans_Agy99           GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGGVG
Mflv_5091|M.gilvum_PYR-GCK          ---GTGQNGGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLG
Mvan_1264|M.vanbaalenii_PYR-1       ---GTGQNGGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLG
MSMEG_0868|M.smegmatis_MC2_155      ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAG
TH_3810|M.thermoresistible__bu      -------------GDGGSGG----------RTGLFSKLSRGGDGGDGGLG
MAB_4284c|M.abscessus_ATCC_199      -------TGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHND
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----AADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAA
                                                                                      

Rv3511|M.tuberculosis_H37Rv         ------APGGNGGNAG--WLYGRGGVGGAGGIGGG------TGGAGGHAW
Mb3541|M.bovis_AF2122/97            ------APGGNGGNAG--WLYGRGGVGGAGGIGGG------TGGAGGHAW
MMAR_4999|M.marinum_M               G-----GAGGVGGNGG--WLYGRGGVGGAGGMGGG------TGGAGGHAW
MUL_4367|M.ulcerans_Agy99           AAGMTGGSGGAGGGGG--WLWGAGGSGGAAGAGG-------SGGSGG--W
Mflv_5091|M.gilvum_PYR-GCK          G-----GNGGNGGNAGAFALFGNGGNGGNGGVGVVG-----ATGAVGAPG
Mvan_1264|M.vanbaalenii_PYR-1       S-----GDGGNGGDAGLFSLFGRGGNGGNGGVGIAG-----ATGAVGAPG
MSMEG_0868|M.smegmatis_MC2_155      ------LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGG
TH_3810|M.thermoresistible__bu      ------GNGGHGGGTGIISLLSLAGNGGNGGNGYR---------------
MAB_4284c|M.abscessus_ATCC_199      T-----DFASHNPIASGNQVMSPSGNVDSFNRGPLL-------DLSFGDL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDG-------SIPDVYK
                                                                                      

Rv3511|M.tuberculosis_H37Rv         LFGHGGTGGIGGG-------PGGNGGWLLGNGGHGGAG------------
Mb3541|M.bovis_AF2122/97            LFGHGGTGGIGGG-------PGGNGGWLLGNGGHGGAG------------
MMAR_4999|M.marinum_M               LFGHGGTGGLGGGGGIGAGGAGGNGGLLYGHGGAGAAGGAGQAGGDGGSA
MUL_4367|M.ulcerans_Agy99           LWGNAGQTAGAG--------VGGAG----GAGGAGDAGDQ----------
Mflv_5091|M.gilvum_PYR-GCK          VAGATGATGVTSG------VVGGNGEDAVGYGATGAAG------------
Mvan_1264|M.vanbaalenii_PYR-1       VAGATGATGVTSN------VTGGNGADAVGYGATGAAG------------
MSMEG_0868|M.smegmatis_MC2_155      TGGGTGGTGGIGG------TGGGLFGLLGHSGSTGAAGAAG---------
TH_3810|M.thermoresistible__bu      ---TTDNNALDGG-------------------------------------
MAB_4284c|M.abscessus_ATCC_199      QFGNRDTTAIGDG-------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                QQIRAESYGDAAG-------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         ------------GIG----------------------GGSGGAGGNGGWL
Mb3541|M.bovis_AF2122/97            ------------GIG----------------------GGSGGAGGNGGWL
MMAR_4999|M.marinum_M               GLWGRGGAGGAAGVGGSTGGSGGNGGLLIGAGASGGAGTSGGAGGHGGWL
MUL_4367|M.ulcerans_Agy99           ---------GVS-------------------------GVAPGEAGAVGFA
Mflv_5091|M.gilvum_PYR-GCK          ---------------------------------------AAGAAGAAGAA
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------------------------AAGAAGAAGKA
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------------NGGDGGNGGFGYV
TH_3810|M.thermoresistible__bu      ---------------------------------------HGGNGGNVGFF
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------AVAVGGSNSGPIA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------------------------QLSAMVAGLEKLE
                                                                                      

Rv3511|M.tuberculosis_H37Rv         LGNGGIGGAGGT----GGGAGGTGGNAAWLL----GGGGTGGAGGIGGGN
Mb3541|M.bovis_AF2122/97            LGNGGIGGAGGT----GGGAGGTGGNAAWLL----GGGGTGGAGGIGGGN
MMAR_4999|M.marinum_M               IGDGGPGGTGGD----GGGSGGSGGDAAWLF----GNGGAGGAGGIGGGT
MUL_4367|M.ulcerans_Agy99           GGAGGAGGAGGNGV--GGGVNGAGG-AGGAG----GVGGGGGAGASGVGA
Mflv_5091|M.gilvum_PYR-GCK          GAVGSAGAAGEA------GETGTWGNAGLPG----KAGDAGGAGAVG---
Mvan_1264|M.vanbaalenii_PYR-1       GAVGSAGTAGSA------GAPGVWGNAGLPG----AAGAAGGAGAIG---
MSMEG_0868|M.smegmatis_MC2_155      LIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGA
TH_3810|M.thermoresistible__bu      SLFN--------------------------------LGGAGG--------
MAB_4284c|M.abscessus_ATCC_199      SGQGSTAVNGDVR------DSNIINADHGSN-----VGVDQSQTRVG---
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                SLPGGLLLVGSG------------------------VDVAPLKQVLQTTT
                                                                                      

Rv3511|M.tuberculosis_H37Rv         GGHGGNGGWLLGNGGNGGLGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGN
Mb3541|M.bovis_AF2122/97            GGHGGNGGWLLGNGGNGGLGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGN
MMAR_4999|M.marinum_M               GGQGGDGGFLIGNAGSGGIGGIGATGTPGGHGGDGGNPGWLLGAAGTGGL
MUL_4367|M.ulcerans_Agy99           GVAGGDG----GTGGAGGAAGVGGAAGTGGTGGAAGVAG-TGGDGGDGGA
Mflv_5091|M.gilvum_PYR-GCK          ------------AAGAAGTVGTAGATGGTGTGANG-------GAGGVGGV
Mvan_1264|M.vanbaalenii_PYR-1       ------------TAGVAGAAGTAGATGGTGVGGNG-------GAGQAGGI
MSMEG_0868|M.smegmatis_MC2_155      NGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTA
TH_3810|M.thermoresistible__bu      -------------WGGSGVDGVDVVGGN-----------------PDGGT
MAB_4284c|M.abscessus_ATCC_199      -------------GDYTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------FLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQD
                                                                                      

Rv3511|M.tuberculosis_H37Rv         GGAGSTGTAGGGSGGTGGDGGTGGRG--GLLMGAGAGGHGGTGGAGGAGV
Mb3541|M.bovis_AF2122/97            GGAGSTGTAGGGSGGTGGDGGTGGRG--GLLMGAGAGGHGGTGGAGGAGV
MMAR_4999|M.marinum_M               GGAGGAAASTGTAGGVGGDGGAGGRG--GLFMHGGAGGNGGTGGAGAGGT
MUL_4367|M.ulcerans_Agy99           GGAGSDASLAGQAGFAGGSGGAGGVG--GSAGAGGVNGSGGDGGAGAAGG
Mflv_5091|M.gilvum_PYR-GCK          GGTG-AAGAAGGAGGLGETGTTGGAG--GVGGQGTAGGTGGVGGIGGAGS
Mvan_1264|M.vanbaalenii_PYR-1       GGTG-AAGAAGQAGTAGETGVTGGVG--GIGGQGTEGGTGGVGGVGGVGA
MSMEG_0868|M.smegmatis_MC2_155      TGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGG
TH_3810|M.thermoresistible__bu      PGAHGESHTPGVYTDRQGEDGEDGTG-------TGIGGRGGNGGSSS---
MAB_4284c|M.abscessus_ATCC_199      TDRSTNIGSGNTTNTEIGSHNQANIG-----TSTSAGGSAAVGGNAGLAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PGTGAVDQYSLPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFL
                                                                                      

Rv3511|M.tuberculosis_H37Rv         NGGGAG---GAGGAGGNGGAGGQAALLFGRGGTGGAGGYGGDGGGGGDGF
Mb3541|M.bovis_AF2122/97            DGGGAG---GAGGAGGNGGAGGQAALLFGRGGTGGAGGYGGDGGGGGDGF
MMAR_4999|M.marinum_M               DGGGSG---GAGGAGGNGGAGGRAPLLFGRGGTGGYGGSGGSGGHGGTGL
MUL_4367|M.ulcerans_Agy99           AGGASATVAGSGGVGGDGGAGGAAGGGVGAASLGGDGGHAGAGGAGGEGL
Mflv_5091|M.gilvum_PYR-GCK          TG-------AVGGVGGKGIQG-------GQGLQGGKGGDGGAGGKGGD--
Mvan_1264|M.vanbaalenii_PYR-1       TG-------GAGGVGGKGIQG-------GQGLQGGQGGDGGTGGTGGD--
MSMEG_0868|M.smegmatis_MC2_155      AGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTT
TH_3810|M.thermoresistible__bu      ----------------------------GTHPMAEDGEHVKALD------
MAB_4284c|M.abscessus_ATCC_199      NAG-----------------------LAGNAGLAGNAGLAGNAGLAGN--
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PEDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTPN
                                                                                      

Rv3511|M.tuberculosis_H37Rv         DG-----TMAGLGGTGGSGGTGGD----GGAPGNGGAGGAGQLLSHSGVA
Mb3541|M.bovis_AF2122/97            DG-----TMAGLGGTGGSGGTGGD----GGAPGNGGAGGAGQLLSHSGVA
MMAR_4999|M.marinum_M               DG-----NLAGLGGDGGGGGTGGD----GGAPGTGGAGGARHLFSHNGRS
MUL_4367|M.ulcerans_Agy99           SGGFNTGAAGGIGGAGGAGGTGGDSGGVGGVNGDGGAGGGGGRGGDGGSS
Mflv_5091|M.gilvum_PYR-GCK          --------ADSMGSAGATGGKGGN----------GGNGGRGGLFGKGGNA
Mvan_1264|M.vanbaalenii_PYR-1       --------ATSMGEAGATGGKGGN----------GGNGGRGSLFGRGGNA
MSMEG_0868|M.smegmatis_MC2_155      GGKASGTAKAGHGGKASDGGKGGN----GGDALVMAAGATGVATGNTAIG
TH_3810|M.thermoresistible__bu      ------------GRPGLDGGNGSH--------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------AGLAGNAGLAGN----------AGLAGNAGLAGNAGLA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                QHLIVPTEQAPAPPPVQASAPQPK------ISVPEPVAAPKPLSPPVAAP
                                                                                      

Rv3511|M.tuberculosis_H37Rv         GAS-GKGGAGGTGGNGGAGSAGADAPAGSGAMGSTGFAGGAGGDGGNGGG
Mb3541|M.bovis_AF2122/97            GAS-GKGGAGGTGGNGGAGSAGADAPAGSGAMGSTGFAGGAGGDGGNGGG
MMAR_4999|M.marinum_M               GST-GIGGAGGSGGRGGDGAAGTDAAANSGAIGGTGFSGGAGGAGGVGGG
MUL_4367|M.ulcerans_Agy99           TSTSGVGGAGGAGGNGGNAGFGVSAGG----------TGGSAGDGGAGGG
Mflv_5091|M.gilvum_PYR-GCK          GNG-ADGGTGGAGGAGGTGG-----------------TGGAGGTGGTGG-
Mvan_1264|M.vanbaalenii_PYR-1       GNG-GNGGTGGNGGNGGTGG-----------------TGGNGGTGGTGG-
MSMEG_0868|M.smegmatis_MC2_155      GNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGG
TH_3810|M.thermoresistible__bu      ------GGNGGHGGRGGFLG-----------------IGGSGGWGGHGGN
MAB_4284c|M.abscessus_ATCC_199      GNA-GLAGNAGLAGNAGLAG-----------------NAGLAGNAGLAGN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                LPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSP
                                                                                      

Rv3511|M.tuberculosis_H37Rv         SGASQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGN
Mb3541|M.bovis_AF2122/97            SGASQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGN
MMAR_4999|M.marinum_M               AGANQGAGGQGGDGGTGGTGGDGGDGAAGTDPLLAAQAGGQGGDGGTGGT
MUL_4367|M.ulcerans_Agy99           AGGVDGVGGASGNGGAAGAGGAGGSGIG------AGIDGGAGGAGGTGGA
Mflv_5091|M.gilvum_PYR-GCK          TGGIGGAGSTGGTGGTGGTGGTGG-------------TGGTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       TGGIGGAGSTGGTGGTGGTGGTGG-------------TGGTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155      NGWVQAYDPNGPAGTTIDKGKAAGGNGG---------DGGFNGTGGATGG
TH_3810|M.thermoresistible__bu      GGDTDADGGNGGDGGN----------------------GGSAGRGGTGGL
MAB_4284c|M.abscessus_ATCC_199      AGLAGNAGLAGNAGLAGNAGLAGN--------------AGLAGNAGLAGN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PQLLAPPRLSVPQPVQPPVRVPQP--------------PSPPQVGGTVPQ
                                                                                      

Rv3511|M.tuberculosis_H37Rv         AGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAG
Mb3541|M.bovis_AF2122/97            AGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAG
MMAR_4999|M.marinum_M               AGTGGTGSTMGTDGTAGDGGTGGAGGHGGTGADNTTVVGAGAMGAAGGQG
MUL_4367|M.ulcerans_Agy99           AGFPGGGGTTGAWGTGGAGGAGGAGGAGDHGGVGVNPGDSGTAGWAGGAG
Mflv_5091|M.gilvum_PYR-GCK          GGTGGKGGTGGTGGAGGTGGDGGTGGTGGTGGTGGTGGTGGTGGAGDGTG
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGKGGTGGTGGDGGTGGTGGTGGTGGTGGTGGTGGTGGTGGAGDGLG
MSMEG_0868|M.smegmatis_MC2_155      RGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNG-GAG
TH_3810|M.thermoresistible__bu      RG------VFGINGGNGRAGLGGRGXXXXGGGVGAAVRSG--NGVFSGGG
MAB_4284c|M.abscessus_ATCC_199      AAVAGNAAVAGNAAVAGNAAVGGVLNTGVSGAIGGSSHVGGAINESLGGS
MLBr_01183|M.leprae_Br4923          -------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPP
MAV_4827|M.avium_104                SPPQHQTPPGEGTPPKPDGPGNYGGGHVPTPGAGGSGGSGGGHVPTPGAG
                                                                   .       .       .  

Rv3511|M.tuberculosis_H37Rv         GAGGTG---GAAGTGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLA
Mb3541|M.bovis_AF2122/97            GAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLA
MMAR_4999|M.marinum_M               GAGGTGGTGGAAGTGGGGLQGAGGQGGDGGTGGTGGDGGDGAAGTDPLLA
MUL_4367|M.ulcerans_Agy99           GAGGAG--------GSAAFNGVNGAGGAGGNGGAGGGGGAGASGIGAGVA
Mflv_5091|M.gilvum_PYR-GCK          GTGGTG--------GTGGQGGQGGQGGTGGTGGQGGLGG----------G
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTG--------GTGGFGGQGGQGGTGGTGGQGGLGG----------V
MSMEG_0868|M.smegmatis_MC2_155      GAGGVS-------EGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGK
TH_3810|M.thermoresistible__bu      GTPSAG---------FGVPTTIQFPAGSCTSRAVS---------------
MAB_4284c|M.abscessus_ATCC_199      GSVGGS-------TAVGGGAHTGVGGGVSTGVGVGSHVG----------G
MLBr_01183|M.leprae_Br4923          AADDVS------------ILLAHFFSGHGR--------------------
MAV_4827|M.avium_104                GSGGSG----------GGHVPTPGTGGPGGTGGSGGGHVP---------T
                                    .: . .                   .*                       

Rv3511|M.tuberculosis_H37Rv         AQDGGQGGTG---------GTGGNAGAGGTGFTPRRRRQRRQRR------
Mb3541|M.bovis_AF2122/97            AQDGGQGGTG---------GTGGNAGAGGTGFTQGADGNAGNGGDGGVGG
MMAR_4999|M.marinum_M               AQAGGQGGDG---------GTGGTAGTGGTGSTMGTDGTAGDGGTGGAGG
MUL_4367|M.ulcerans_Agy99           GGDGGTGGTG---------GAAGTGGAAGTGGTGGAAGAAGSAGDGGAGG
Mflv_5091|M.gilvum_PYR-GCK          GGTGGQGGTG---------GTGGQGGTGGTGGTGGTGGTGGAGGDGGLGG
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTGGTG---------GTGGQGGTGGTGGTGGTGGTGGAGGDGGLGG
MSMEG_0868|M.smegmatis_MC2_155      GGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGG
TH_3810|M.thermoresistible__bu      -REGIMPSSR---------AASARAGAACASSTSRSRRSFCCSRA-----
MAB_4284c|M.abscessus_ATCC_199      GISESLGGSG---------SVGGSTAVGGGAHTGVGGGVSTGVGVGSHVG
MLBr_01183|M.leprae_Br4923          -QYQAHASQG------------ATNHQDLIQSLLTSSSAYAGTETANHDS
MAV_4827|M.avium_104                PGAGTPGGSG-----------GGHLPFPGAGSTPGGSGGGHLPTPGAG--
                                           .              .                           

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            NGGNGADNTTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTGGQQGNGGNG
MMAR_4999|M.marinum_M               HGGTGADNTTVVGAGAMGAAGGQGGAGGTGGTGGAAGTGGGGLQGAGGQG
MUL_4367|M.ulcerans_Agy99           AGGAGDDGSAGVVSGDPGTAGKAGGAGGAGGVGGNG--VAGGVNGSGGAG
Mflv_5091|M.gilvum_PYR-GCK          LGG----------FGGSGGTGGQGGLGGPGGS-------------TGGAG
Mvan_1264|M.vanbaalenii_PYR-1       LGG----------FGGVGGTGGQGGQGGPGGS-------------TGGAG
MSMEG_0868|M.smegmatis_MC2_155      NGGNG---------DADGHRGGKGGDGGEALIRATVIGSNASGTATGGDG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGIS----------ESLGGSGSVGGSTAVGG---------------GAHT
MLBr_01183|M.leprae_Br4923          L-------------------------------------------------
MAV_4827|M.avium_104                --------------TPGGGLGGFGGGHAPAPG--------------GGLG
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GNGGTGGKG-GTGGAGMNSLDPLLAAQDGGQG----GTGGTGGNAGAGGT
MMAR_4999|M.marinum_M               GDGGTGGTG-GDGGDGAAGTDPLLAAQAGGQG----GDGGTGGTAGTGGT
MUL_4367|M.ulcerans_Agy99           GAGGAGGTG-GAGASGVP------ASVDGGDG----GAGGAGGAAGTGGS
Mflv_5091|M.gilvum_PYR-GCK          GAGGQAGTA-GKGG------------LFGGSG----SAGKAGATGAAGAS
Mvan_1264|M.vanbaalenii_PYR-1       GAGGQAGVA-GKGG------------LFGGSG----SAGTAGVTGASGAS
MSMEG_0868|M.smegmatis_MC2_155      GNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GVGGGVNTGVGVGS-----------------------HVGGGISESLGGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GGGGHAPAPGGGLG----------------------GFGGGHSGGGLGGL
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGAGGTG
MMAR_4999|M.marinum_M               GSTMGTDGTAGDGGTGGAGGHGGTGADNTTVVGAGAMGAAGGQGGAGGTG
MUL_4367|M.ulcerans_Agy99           GGSAGNTG-------------------------------AGGAGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK          GGKG-----------------------------------AQGATGAQGAT
Mvan_1264|M.vanbaalenii_PYR-1       GGKG-----------------------------------AQGATGAQGAT
MSMEG_0868|M.smegmatis_MC2_155      GGQGTIEANGPS--------------------------AVASGIGAGGNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GSVGG----------------------------------STAVGGGAHTS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GGGHK---------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGDGALAGSSGGAGGKGGN
MMAR_4999|M.marinum_M               GTGGAAGTGGGGLQGAGGQGGDGGTGGTGGDGGDG-IDNSTDMTGKAGGD
MUL_4367|M.ulcerans_Agy99           GSAASTG-------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GAQGATG-------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GAQGATG-------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GDGIDGG-------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AINDALG-------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GGDAGKAGTGSAPGTAGTGGDGGKGGNGGIGAAGTTGPVGTGASGGTGGS
MMAR_4999|M.marinum_M               GGQGGDGGTGGTAGTGGTG--------------STMGATGTGGTGGVGGS
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GGAGGTGGDGGAANGGTAGAGGAGGNGGKGGDGGAGVTSSTAGNSGGAGG
MMAR_4999|M.marinum_M               GGTGGHGGHGPLNSD-----------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            SGGKGGDAGAGGAGATPGANGIAGNGGDGGDGAAGAVGISGATGAGDGGH
MMAR_4999|M.marinum_M               -------------------------------------------------P
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GGTGGAGGNGGTGGAGGSGIDGVGGGTGGTGGNGGNGAIGGAGGDAGGSG
MMAR_4999|M.marinum_M               GGAGGKGGDGGTGGTGGAGIGTSGGGTGGDGGAAGDGGTGGDGGEVGGTG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            NSGGNGGTGGKGGNAGAGGAAGSNGGTVGANGTGGDGGNGGAAGAATAGS
MMAR_4999|M.marinum_M               GVGGAAGTGGDGGDGGTG--------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            NGGAGTGSAGGNGGTGGRGGSGGAGGDGIGGVGGGKGGNGADGEVGGAGG
MMAR_4999|M.marinum_M               ------GGDGGKGGTGGTGGTGGIGDPRVG--------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            AGGSGPNTSPGGNGGQGGQGGSGGAGGAAGAGGAGGGANGTAGNGGQGGA
MMAR_4999|M.marinum_M               --------GSGGDGGAGGIGGVAGAGGQGGNAGAGG--NGTGGDGGNGGI
MUL_4367|M.ulcerans_Agy99           ----------------------------------------VNGDGGAGGA
Mflv_5091|M.gilvum_PYR-GCK          ------------------------------------------ATGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------------ATGASGAQ
MSMEG_0868|M.smegmatis_MC2_155      ----------------------------------------LGGNGGDGVV
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------------GSGSVGGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GGTGGAGAASSATNGGSGGAGGTGGAGGTGGAGGDGVGGAGGGNGGHGGD
MMAR_4999|M.marinum_M               GGTGGVGGDAEPGAGGNGGAGGHGGTGGAAGAGGSGSGSGADGSSGMG--
MUL_4367|M.ulcerans_Agy99           GGVGGLGGDSAATAGG-GGAGGDGGKGGAGGAG-----------------
Mflv_5091|M.gilvum_PYR-GCK          GATGAAGAAGAAGSAGTTGAQGSAGTNGANGAN-----------------
Mvan_1264|M.vanbaalenii_PYR-1       GSAGSAGSAGVAGSAGTTGAQGSAGTNGANGAN-----------------
MSMEG_0868|M.smegmatis_MC2_155      NTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLG--
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      TAVGGGAHTSAINESMNSSINASHSSSMNESFG-----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            AGDGGNGANGNNRSSGSFLAAGGTGGAAGDGGQGGQGGAGGGAGGQGGAG
MMAR_4999|M.marinum_M               -----------------------------------------GTGGQGGDG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GAGGTGGNGGNITGGTAGTAGAAGNGGAAGKGGAGGQGGTGGGTGGQGGA
MMAR_4999|M.marinum_M               GAGSTGANAANGSGATG----------------------KAGFAGGKGGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GGDGGAGGTGGDRTVGGGTVPAGSGGQGGNAGGGGAGGQGGADGGSGGDG
MMAR_4999|M.marinum_M               GGDGGAG----------------------------IGGVGGGDGGNGGSG
MUL_4367|M.ulcerans_Agy99           -----------------------------------VNGVGGGDGGKGG--
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      -----------------------------------GNATGTATAGKGG--
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GDAGTGGNGGNGGNRNSGNGTGGAGGNGGGGANGGAGGAGGSGGGTGGNG
MMAR_4999|M.marinum_M               GLGGDGGNGGSGG----TNQTGGKGGAGGTGGDGGAAGAGGAGGGANGSG
MUL_4367|M.ulcerans_Agy99           --------------------TGGAGGAGGAGSDGIIPSNGGLGG------
Mflv_5091|M.gilvum_PYR-GCK          ---------------------GSQGAAGKAGATG----------------
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------GSQGAAGKAGATG----------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------EASNGGVAGNGGNALVMAAGTTGVATG---
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------SSMGSHGAAG----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GAGGDAGDAGNGGNGNGTGNGGNGGNGGIAGMGGNGGAGTGSGNGGNGGS
MMAR_4999|M.marinum_M               GTG---------------------------------------GTGGTGGD
MUL_4367|M.ulcerans_Agy99           ----------------------------------------------NGGN
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ----------------------------------------------NTAT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GGNGGNAGMGGNSGTGSGDGGAGGNGGAAGTGGTGGDGGLTGTGGTGGSG
MMAR_4999|M.marinum_M               GGKGGTVTGNGKAGTTGGAGGAGGAGGAGGDG-IGSTGG--GTGGVGGNA
MUL_4367|M.ulcerans_Agy99           GGNGGQAFGDG----VGGAGGIGGKGGNAAIGTIVINGGVGGAGGSGGLG
Mflv_5091|M.gilvum_PYR-GCK          ---------------TTGATGAAGEDGDAGSGGSGINGGAGGAGGAGG--
Mvan_1264|M.vanbaalenii_PYR-1       ---------------TTGATGAAGDAGDPGSEAVDINGGAGGAGGAGG--
MSMEG_0868|M.smegmatis_MC2_155      GGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------TGFEAQGHAQGHASETAHTTLPGAEHH-------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GTGGDGGNGGNGGNGADNTANMTAQAGGDGGNGGDGGFGGGAGAGGGGLT
MMAR_4999|M.marinum_M               GDGGDGGNGSNGGNGNSD--------------------------------
MUL_4367|M.ulcerans_Agy99           GATEDG--------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ADGWVQAYDPAGPVG-----------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            AGANGTGGQGGAGGDGGNGAIGGHGPLTDDPGGNGGTGGNGGTGGTGGAG
MMAR_4999|M.marinum_M               --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            IGSLGGGTGGDGGNGGTGGNGGTGGEGGEVGGAGGTGGAAGNGGDGGTGG
MMAR_4999|M.marinum_M               ------------------------------GGTGGTGGAAGAGGTGGVGG
MUL_4367|M.ulcerans_Agy99           --------------------------------VGGVGCAGGAGGNGGRGD
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------EGGEGGDGGKGGAG----
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------EGGEGGAGGAGGDG----
MSMEG_0868|M.smegmatis_MC2_155      ------------------------------SKIANSSAVAGNGGDGGVNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            TGGGDGGAGGTGGTGGTGGLGDPRVGGSGGDGGTGGSGGAAGNGGNGGNA
MMAR_4999|M.marinum_M               SGGGDGGAAGAGGTGGNGGKGGNARLNGNGDGGMGGQGGAAGTGGIGGAA
MUL_4367|M.ulcerans_Agy99           MLFTVGGSGGTGGDGGGGG-------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ---AEGGAGGGGG-------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---SEGGAGGSGG-------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TGGASGGDGGNGGNTSVWK-------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GAGGNGNGGTGGAGGIGGTGGNGGDAEPGVPPGAGGAGGAGTTGGKGGTG
MMAR_4999|M.marinum_M               GAGGNGNGGAGGTGGVGGGGGDGGTGGSSGKGGDGGTGGTGAVGGMGGAG
MUL_4367|M.ulcerans_Agy99           SASGSGTGGSGGTGGVGGIGGDGKLGGFGGDGGDGGDGGFGVIGGQGGGG
Mflv_5091|M.gilvum_PYR-GCK          -AGGSGAGGAGGAGGSGGSGGSGGSGGSGGAAGDSDD-------------
Mvan_1264|M.vanbaalenii_PYR-1       -AGGSGTGGAGGAGGSGGSGGSGGAGGSGGAAGDSD--------------
MSMEG_0868|M.smegmatis_MC2_155      -SGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GNGSGTGSGGTGGDGGTGGGGGNGGTGWNGGKGDTGSG-GGAGDGGKAPA
MMAR_4999|M.marinum_M               GSGTGTGTGGTGGDGGDGGDGGDGGGGDGGAIPGTGGGDGGSGDTGNLPV
MUL_4367|M.ulcerans_Agy99           GFG---GLGGTGAGGAPSDKGINGEPGNPG--------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGGNGGNGGADGTPGTAGTTGANNP---------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3511|M.tuberculosis_H37Rv         ----------------------
Mb3541|M.bovis_AF2122/97            GGTGGAGGDGGAGGKGGSGGV-
MMAR_4999|M.marinum_M               GVTGGTGGTGGTAGTAGAGGLT
MUL_4367|M.ulcerans_Agy99           ----------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------
MSMEG_0868|M.smegmatis_MC2_155      ----------------------
TH_3810|M.thermoresistible__bu      ----------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------
MLBr_01183|M.leprae_Br4923          ----------------------
MAV_4827|M.avium_104                ----------------------