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VTRLSASDASFYQLENTATPMYVGLLLILRRPRAGLSYEALLETVEQRLPQIPRYRQKVQEVKLGLARPV WIDDRDFDITYHVRRSALPSPGSDEQLHELIARLAARPLDKSRPLWEMYLVEGLEKNRIALYTKSHQALI NGVTALAIGHVIADRTRRPPAFPEDIWVPERDPGTTRLLLRAVGDWLVRPGAQLQAVGSAVAGLVTNSGQ LVETGRKVLDIARTVARGTAPSSPLNATVSRNRRFTVARASLDDYRTVRARYDCDSTTWC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3234c | - | - | 100% (271) | hypothetical protein Rv3234c |
| M. tuberculosis H37Rv | Rv1425 | - | 1e-35 | 36.78% (261) | hypothetical protein Rv1425 |
| M. tuberculosis H37Rv | Rv3130c | tgs1 | 3e-29 | 31.70% (265) | triacylglycerol synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3262c | - | 1e-150 | 100.00% (266) | hypothetical protein Mb3262c |
| M. gilvum PYR-GCK | Mflv_4703 | - | 1e-117 | 74.81% (266) | hypothetical protein Mflv_4703 |
| M. leprae Br4923 | MLBr_01244 | - | 3e-20 | 31.55% (206) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_3551c | - | 1e-99 | 63.91% (266) | hypothetical protein MAB_3551c |
| M. marinum M | MMAR_1311 | - | 1e-130 | 83.08% (266) | hypothetical protein MMAR_1311 |
| M. avium 104 | MAV_4196 | - | 1e-129 | 83.46% (266) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_1882 | - | 1e-115 | 72.93% (266) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_2686 | - | 1e-120 | 76.69% (266) | PUTATIVE Diacylglycerol O-acyltransferase |
| M. ulcerans Agy99 | MUL_1818 | - | 5e-35 | 37.07% (259) | hypothetical protein MUL_1818 |
| M. vanbaalenii PYR-1 | Mvan_1764 | - | 1e-116 | 74.81% (266) | hypothetical protein Mvan_1764 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3234c|M.tuberculosis_H37Rv -------MVTRLSASDASFYQLENTATPMYVGLLLILRRPRA-GLSYEAL
Mb3262c|M.bovis_AF2122/97 -------MVTRLSASDASFYQLENTATPMYVGLLLILRRPRA-GLSYEAL
MMAR_1311|M.marinum_M -------MVTRLSNTDASFYRLENTATPMYVGSLMILRRPRA-GLSYEAL
MAV_4196|M.avium_104 -------MVSRLSPADASFYRLENTATPMYVGSLAILRRPRA-GLSYETL
Mflv_4703|M.gilvum_PYR-GCK -------MVTRLSASDASFYRLENSSTPMYVGSLQILRRPRS-GLSYETL
Mvan_1764|M.vanbaalenii_PYR-1 -------MVTRLSASDASFYRLESSSTPMYVGSLQILRKPRN-GLSYETL
MSMEG_1882|M.smegmatis_MC2_155 -------MVTRLSASDAAFYRLENTSTPMYVGSLSILRKPRA-GLSYETL
TH_2686|M.thermoresistible__bu -------MVTRLSASDADFFHLEDTSTPMYVGSLAILRRPRG-GLSYETL
MAB_3551c|M.abscessus_ATCC_199 MGKAARIVVSRLSALDASFYSSEDSATPMHVGSLAIIRRPRG-GFTYEEL
MUL_1818|M.ulcerans_Agy99 --------MRRLSSVDAAFWSAETAGWHMHVGALAICDPTDAPDYSFQRL
MLBr_01244|M.leprae_Br4923 -MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWNRF
: :. .* : . . : :: :
Rv3234c|M.tuberculosis_H37Rv LETVEQRLPQIPRYRQKVQEVKLGLARPVWIDDRDFDITYHVRRSALPSP
Mb3262c|M.bovis_AF2122/97 LETVEQRLPQIPRYRQKVQEVKLGLARPVWIDDRDFDITYHVRRSALPSP
MMAR_1311|M.marinum_M LATVEQRLAQIPRYRQKVREVRIGMARPVWIDDPDFDITYHVRRSALPSP
MAV_4196|M.avium_104 LHTIEQRLPQIPRYRQKVREVPVGTARPVWIDDGDFDITYHVRRSALPSP
Mflv_4703|M.gilvum_PYR-GCK LATVEQRLPQIPRYRQKVREVTLGLARPVWVDDRDFDITYHIRRSALPSP
Mvan_1764|M.vanbaalenii_PYR-1 LATVEQRLPLIPRYRQKVREVSFGLARPVWVDDREFDITYHVRRSALPSP
MSMEG_1882|M.smegmatis_MC2_155 LETVEKRLPQIPRYRQKVREVTLGLARPVWIDDREFDITYHIRRSALPSP
TH_2686|M.thermoresistible__bu LATVEQRLPQIPRYRQKVRKAPIGLARPVWVDDPDFDITYHVRRSALPSP
MAB_3551c|M.abscessus_ATCC_199 LALVESRLPQVPRYRQKVKEIGFGLARPVWLDDVDFDITYHIRRSALPSP
MUL_1818|M.ulcerans_Agy99 RELLIERLPEIPQLRWRVTGAPLGLDRPWFVEDQDLDVDFHVRRIGVPAP
MLBr_01244|M.leprae_Br4923 RSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRVPDP
: . : : * :* . * :: * :::: :*:** :* *
Rv3234c|M.tuberculosis_H37Rv GSDEQLHELIARLAARPLDKSRPLWEMYLVEGLEKNRIALYTKSHQALIN
Mb3262c|M.bovis_AF2122/97 GSDEQLHELIARLAARPLDKSRPLWEMYLVEGLEKNRIALYTKSHQALIN
MMAR_1311|M.marinum_M GSDEQLHELIARLAARPLDKSRPLWEMYLIEGLEKGRVALYTKTHQALIN
MAV_4196|M.avium_104 GSDEQLHELIARLAARPLDKTRPLWEMYLVEGLSKNRLALYTKSHQALIN
Mflv_4703|M.gilvum_PYR-GCK GSDTQLHDLVARLGSRPLDKTRPLWEMYLAEGLAKNRVAIYTKSHQALVN
Mvan_1764|M.vanbaalenii_PYR-1 GSDAQLHDLVARLGSRPLDKSRPLWEMYLVEGLAKNRIAIYTKSHQALVN
MSMEG_1882|M.smegmatis_MC2_155 GSDAQLHDLVARLGSRPLDKTRPLWEMYLVEGLAGNRIAVYTKSHQALVN
TH_2686|M.thermoresistible__bu GSDAQLHELIARLASRPLDKTRPLWEMYLIEGLAKNRLALYTKSHQALVN
MAB_3551c|M.abscessus_ATCC_199 GSDGQLQDLVARLTSRPLDRSRPLWEMYLVEGLSKNRLAIYTKTHQALVD
MUL_1818|M.ulcerans_Agy99 GGRRELEELVGRLMSYKLDRSRPLWELWVIEGVEGGRIATLTKMHHAIVD
MLBr_01244|M.leprae_Br4923 GTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHAITD
* :: :* : :* :**** : **: .* * : :*: :
Rv3234c|M.tuberculosis_H37Rv GVTALAIGHVIADRTRRPPAFPEDIWVPERDPGTTRLLLRAVGDWLVRPG
Mb3262c|M.bovis_AF2122/97 GVTALAIGHVIADRTRRPPAFPEDIWVPERDPGTTRLLLRAVGDWLVRPG
MMAR_1311|M.marinum_M GVTALSLGHVIADRTQRPPPFPEDIWIPERDPGNTRLVMGAIGDWVVGPG
MAV_4196|M.avium_104 GMTALEINHVIADRTKRPPAFPEDIWVPERDPGNTRLVLGAIGEWLVGPS
Mflv_4703|M.gilvum_PYR-GCK GMAALEIGHVIADRTQKPPEFGEDIWIPGREPSDRQLLLGAVGEWITRPT
Mvan_1764|M.vanbaalenii_PYR-1 GMTALEIGHVIADRTQKPPAFGEDIWIPGREPSDRQLLFGAFGEWITRPT
MSMEG_1882|M.smegmatis_MC2_155 GMSALEVGHVIADRTQKPPEFGEDIWIPSREPTDRQLVLGAIGEWIARPT
TH_2686|M.thermoresistible__bu GMTAPEIGHVIADRTQKPPQFGEDIWMPGREPGTAQLLIGAIGDWLTRPG
MAB_3551c|M.abscessus_ATCC_199 GNSALSLGQVIFDRTARTPDFGEDIWVPEHEPSTSELVAGAVSEWLARPG
MUL_1818|M.ulcerans_Agy99 GVSGAGLGEILLDVTPE-PRPPQEETVGFVGFQIPRLERRAVGALIN--V
MLBr_01244|M.leprae_Br4923 GVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQGINHLPVALA
* . : : * * .. * ...
Rv3234c|M.tuberculosis_H37Rv AQLQAVGSAVAGLVT-----NSGQLVETGRKVLDIARTVARGTAPSSPLN
Mb3262c|M.bovis_AF2122/97 AQLQAVGSAVAGLVT-----NSGQLVETGRKVLDIARTVARGTAPSSPLN
MMAR_1311|M.marinum_M AQLQAVGSAIAGLAT-----NQSQLVNAGRRILDVARNVARGTAPSSPLN
MAV_4196|M.avium_104 AQLQAVGSAIGGLVT-----NYGELVDAGRRVFDFVRNVARGTAPSSPLN
Mflv_4703|M.gilvum_PYR-GCK QQAAAVRSAVTETVS-----STAQIVDLGRRVADVARTVARGTAPSSPLN
Mvan_1764|M.vanbaalenii_PYR-1 AQAAALRSAVTDAVT-----TTGQLVELGRRATEVARTVARGAAPSSPLN
MSMEG_1882|M.smegmatis_MC2_155 SQVAALRDTVTEVAT-----NAGELAAVGRRIADTVRTVARGTAPSSPLN
TH_2686|M.thermoresistible__bu AQMIAVRDNVLGMAT-----NAGELVDAGRRALSVARTVARGTAPSSPLN
MAB_3551c|M.abscessus_ATCC_199 ARLEAVRNTVADVAS-----LTGEIGELGERMVKVVRTAARGAAPRGPLN
MUL_1818|M.ulcerans_Agy99 GIMTPFRIARLVEQT-----VRQQIAALG----VSARPPRYFDAPKTRFN
MLBr_01244|M.leprae_Br4923 GGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQAAEP-SPLL
: * * :
Rv3234c|M.tuberculosis_H37Rv ATVSRNRRFTVARASLDDYRTVRARYDCDSTTWC----------------
Mb3262c|M.bovis_AF2122/97 ATVSRNRRFTVARASLDDYRTVRARYDCDVHDVVLTVIAGALGNWLMSRG
MMAR_1311|M.marinum_M APVSRNRRLTVASGRLEDYRTVRARYDCDVHDVVLAVIAGALGNWLMSRG
MAV_4196|M.avium_104 ATVSRHRRFTVASGSLEDYRTVRARYDCDVNDVVLAVIAGALGSWLMSRG
Mflv_4703|M.gilvum_PYR-GCK TTVSRNRRFSVASGSLDEFRVVRARYDCDVNDVVLAMVAGALRNWLLSRG
Mvan_1764|M.vanbaalenii_PYR-1 TTVSRNRRFSVASGSLDEFRAVRARYDCDVNDVVLAVVAGALRNWLLSRG
MSMEG_1882|M.smegmatis_MC2_155 TTVSRNRRFTVADHKLDDYRQVRVRYDCDINDVVLAVISGALRNWLLSRG
TH_2686|M.thermoresistible__bu TRVSRNRRFTVARHRLDDYRKVRARYDCDVNDVVLAVIAGALRNWLLSRG
MAB_3551c|M.abscessus_ATCC_199 QRVSRSRRFGVVSTKLADYRRVRAKYDCDVNDVVLATIAGALRNWLMSRG
MUL_1818|M.ulcerans_Agy99 AHVSPHRRVSGCRIELARAKAVKDAFGVKLNDVVLATVAGAAREYLKKRD
MLBr_01244|M.leprae_Br4923 RQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYHEALG
* * * : . . .
Rv3234c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3262c|M.bovis_AF2122/97 EAVAPTATVRAMAPLSVYADDQLDSTGPGQAISQVTPFLVDLPVGEGNAV
MMAR_1311|M.marinum_M ETVSQTATVRAMAPLSVYVEDQLDSSGPGQQISQVTPFLIDLPVGERNAV
MAV_4196|M.avium_104 VAVSPTATVRAMAPLSVYADGDLDVSGPGQAISQVMPFLVDLPVGEPNAV
Mflv_4703|M.gilvum_PYR-GCK EPVRATTTVRAMAPMSVYPDAEIDSTGPGQAISEVAPFLVDLPVGESNPV
Mvan_1764|M.vanbaalenii_PYR-1 EPVRATTTVRAMAPMSVYPDTEIDSSSPGQAISEVVPFLVDLPVGEANPV
MSMEG_1882|M.smegmatis_MC2_155 EPVTPSTTVRAMAPLSVYPDEELDSPGPGQAISEVSPFLVDLPVGEGNAV
TH_2686|M.thermoresistible__bu EQVSSTATVRAMAPLSVQSDAELDSTAPGQAVSDVVPFLIDLPVGERNPV
MAB_3551c|M.abscessus_ATCC_199 EPVTTASTIRAMVPMSVYRDGDLDVGGEGAATTEVSPFLVDLPVGEGNTV
MUL_1818|M.ulcerans_Agy99 E--LPAKPLIAQIPVSTRTDQTKEDVG-----NQISSMTASLATHINDPA
MLBr_01244|M.leprae_Br4923 VSISTLP---MAVPVNVRTEADVVGSN------RFVGVTLAAPLGTNDPA
Rv3234c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3262c|M.bovis_AF2122/97 VRLSQIAHATESNPTAASLVDARTIVTLSGLAPATLHAMGVRVAT----S
MMAR_1311|M.marinum_M VRLSQVAHATESNPTAASLVDARTIVTLSGFAPPTLHAMGIRVATSF-PS
MAV_4196|M.avium_104 VRLSQIAHATESNPTAAHLVDARTIVTLSGFAPPTLHAMGIRVATSF-PS
Mflv_4703|M.gilvum_PYR-GCK VRLSQISHATESHPTAPSLVDARTIVTLSGFAPPTLHAMGIRVAT----S
Mvan_1764|M.vanbaalenii_PYR-1 VRLSQISHATETHPTAPSLVDARTIITLSGFAPPTLHAMGIRVAT----S
MSMEG_1882|M.smegmatis_MC2_155 VRLSHITHANESNSWAVSLVDARTIVTLSGFAPPTLHAMGIRVAT----G
TH_2686|M.thermoresistible__bu VRLSQISHATETHPTASSLVDARTIVTLTGFAPATLHAMGVRVAT----N
MAB_3551c|M.abscessus_ATCC_199 VRLSQIAHATESHSAAFSLVDVPNMAALSGFVPPTLHALAARVAS----T
MUL_1818|M.ulcerans_Agy99 ERLKAIHESTQNAKEMAKALSAHQIMGLTETTPPGLLHLAARAYTATGLS
MLBr_01244|M.leprae_Br4923 ARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVDSVASS---
Rv3234c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3262c|M.bovis_AF2122/97 FSARLFNLLITNAPGTQSQMYIAGTKLLETYSVPPLLHNQALAISVTSYN
MMAR_1311|M.marinum_M FSKRTFNLLITNAPGAQSQMYVAGAKLLEAYAVPPLLHNQALAISVTSYN
MAV_4196|M.avium_104 FSKRTFNLLITNAPGAQSQMYVAGTKLLETYSVPPLLHNQALAIGVTSYN
Mflv_4703|M.gilvum_PYR-GCK FSARQFNLLITNVPGAQSQMYIAGTKLLETYSVPPLLHNQTLAIGVTSYN
Mvan_1764|M.vanbaalenii_PYR-1 FSARLFNLLITNAPGAQNQMYIAGTKLLETYAVPPLLHNQALAIGVTSYN
MSMEG_1882|M.smegmatis_MC2_155 FSARLFNLLITNVPGPQKQMYVAGTKLLETYAVPPLLHNQVLAIGVTSYN
TH_2686|M.thermoresistible__bu FSARQFNLLITNVPGAQKQMYIAGTKMLESYSVPPLLRNQVLAVAVTSYH
MAB_3551c|M.abscessus_ATCC_199 LPNRLFNLLVTNVPGPQAPMYLGGARLAEIYPVPPLLRNQVLSIGLTSYN
MUL_1818|M.ulcerans_Agy99 HNLAPINLVVSNVPGPQFPLYMAGARLDSLVPLGPPVMDVALNITCFSYQ
MLBr_01244|M.leprae_Br4923 ------DVNASNIPAYPGDTYFAGAKILRQYGIGPRPG-VAMMAVLMSRG
Rv3234c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3262c|M.bovis_AF2122/97 GMLYFGINADRDAMSDVDLLPGLLSQALDELLEASR--------------
MMAR_1311|M.marinum_M GMLYFGINADRDAMSDVELLPALLAQSLEELLEASR--------------
MAV_4196|M.avium_104 GMLYYGINADREAMSDVDLLPALLNQALEELVEAARS-------------
Mflv_4703|M.gilvum_PYR-GCK GMLYFGINADRDAMSDVDMLPSLLREALDELVEAAR--------------
Mvan_1764|M.vanbaalenii_PYR-1 GMLYFGINADRDAMSDVDMLPSLLRESLDELVEAAR--------------
MSMEG_1882|M.smegmatis_MC2_155 GRLYFGINADRDAMSDVDVFRSLLDESLEELIDAAK--------------
TH_2686|M.thermoresistible__bu GMLYYGVNADRDAMSDVEVLPSLLSESLDELLEAAQ--------------
MAB_3551c|M.abscessus_ATCC_199 GTVYYGINADREAMPDADMLPLLITEALDELLEAAQ--------------
MUL_1818|M.ulcerans_Agy99 EHLDFGFVTTPEVANDIDEMADLIEPALAELERAAGL-------------
MLBr_01244|M.leprae_Br4923 GFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAAR
Rv3234c|M.tuberculosis_H37Rv ------------
Mb3262c|M.bovis_AF2122/97 ------------
MMAR_1311|M.marinum_M ------------
MAV_4196|M.avium_104 ------------
Mflv_4703|M.gilvum_PYR-GCK ------------
Mvan_1764|M.vanbaalenii_PYR-1 ------------
MSMEG_1882|M.smegmatis_MC2_155 ------------
TH_2686|M.thermoresistible__bu ------------
MAB_3551c|M.abscessus_ATCC_199 ------------
MUL_1818|M.ulcerans_Agy99 ------------
MLBr_01244|M.leprae_Br4923 SSGSPAGWLSSS