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MVTRLSASDASFYRLESSSTPMYVGSLQILRKPRNGLSYETLLATVEQRLPLIPRYRQKVREVSFGLARP VWVDDREFDITYHVRRSALPSPGSDAQLHDLVARLGSRPLDKSRPLWEMYLVEGLAKNRIAIYTKSHQAL VNGMTALEIGHVIADRTQKPPAFGEDIWIPGREPSDRQLLFGAFGEWITRPTAQAAALRSAVTDAVTTTG QLVELGRRATEVARTVARGAAPSSPLNTTVSRNRRFSVASGSLDEFRAVRARYDCDVNDVVLAVVAGALR NWLLSRGEPVRATTTVRAMAPMSVYPDTEIDSSSPGQAISEVVPFLVDLPVGEANPVVRLSQISHATETH PTAPSLVDARTIITLSGFAPPTLHAMGIRVATSFSARLFNLLITNAPGAQNQMYIAGTKLLETYAVPPLL HNQALAIGVTSYNGMLYFGINADRDAMSDVDMLPSLLRESLDELVEAAR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_1764 | - | - | 100% (469) | hypothetical protein Mvan_1764 |
M. vanbaalenii PYR-1 | Mvan_3601 | - | 2e-54 | 30.54% (478) | hypothetical protein Mvan_3601 |
M. vanbaalenii PYR-1 | Mvan_4104 | - | 2e-50 | 31.28% (470) | hypothetical protein Mvan_4104 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3262c | - | 0.0 | 77.40% (469) | hypothetical protein Mb3262c |
M. gilvum PYR-GCK | Mflv_4703 | - | 0.0 | 90.62% (469) | hypothetical protein Mflv_4703 |
M. tuberculosis H37Rv | Rv3234c | - | 1e-116 | 74.81% (266) | hypothetical protein Rv3234c |
M. leprae Br4923 | MLBr_01244 | - | 8e-27 | 24.16% (476) | hypothetical protein MLBr_01244 |
M. abscessus ATCC 19977 | MAB_3551c | - | 0.0 | 65.46% (469) | hypothetical protein MAB_3551c |
M. marinum M | MMAR_1311 | - | 0.0 | 74.15% (472) | hypothetical protein MMAR_1311 |
M. avium 104 | MAV_4196 | - | 0.0 | 75.64% (472) | acyltransferase, ws/dgat/mgat subfamily protein |
M. smegmatis MC2 155 | MSMEG_1882 | - | 0.0 | 81.02% (469) | acyltransferase, ws/dgat/mgat subfamily protein |
M. thermoresistible (build 8) | TH_2686 | - | 0.0 | 79.10% (469) | PUTATIVE Diacylglycerol O-acyltransferase |
M. ulcerans Agy99 | MUL_1313 | - | 1e-53 | 31.10% (492) | hypothetical protein MUL_1313 |
CLUSTAL 2.0.9 multiple sequence alignment Mb3262c|M.bovis_AF2122/97 -------MVTRLSASDASFYQLEN-TATPMYVGLLLILRRPRAG---LSY Rv3234c|M.tuberculosis_H37Rv -------MVTRLSASDASFYQLEN-TATPMYVGLLLILRRPRAG---LSY MMAR_1311|M.marinum_M -------MVTRLSNTDASFYRLEN-TATPMYVGSLMILRRPRAG---LSY MAV_4196|M.avium_104 -------MVSRLSPADASFYRLEN-TATPMYVGSLAILRRPRAG---LSY Mvan_1764|M.vanbaalenii_PYR-1 -------MVTRLSASDASFYRLES-SSTPMYVGSLQILRKPRNG---LSY Mflv_4703|M.gilvum_PYR-GCK -------MVTRLSASDASFYRLEN-SSTPMYVGSLQILRRPRSG---LSY MSMEG_1882|M.smegmatis_MC2_155 -------MVTRLSASDAAFYRLEN-TSTPMYVGSLSILRKPRAG---LSY TH_2686|M.thermoresistible__bu -------MVTRLSASDADFFHLED-TSTPMYVGSLAILRRPRGG---LSY MAB_3551c|M.abscessus_ATCC_199 MGKAARIVVSRLSALDASFYSSED-SATPMHVGSLAIIRRPRGG---FTY MUL_1313|M.ulcerans_Agy99 --------MRRLSSVDAQFFAMED-GRNHSHVCQLTIVEATTTDGLRLDG MLBr_01244|M.leprae_Br4923 -MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTT---PDW : :. .* : . . : :. Mb3262c|M.bovis_AF2122/97 EALLETVEQRLPQIPRYRQKVQEVKLGLARPVWIDDRDFDITYHVRRSAL Rv3234c|M.tuberculosis_H37Rv EALLETVEQRLPQIPRYRQKVQEVKLGLARPVWIDDRDFDITYHVRRSAL MMAR_1311|M.marinum_M EALLATVEQRLAQIPRYRQKVREVRIGMARPVWIDDPDFDITYHVRRSAL MAV_4196|M.avium_104 ETLLHTIEQRLPQIPRYRQKVREVPVGTARPVWIDDGDFDITYHVRRSAL Mvan_1764|M.vanbaalenii_PYR-1 ETLLATVEQRLPLIPRYRQKVREVSFGLARPVWVDDREFDITYHVRRSAL Mflv_4703|M.gilvum_PYR-GCK ETLLATVEQRLPQIPRYRQKVREVTLGLARPVWVDDRDFDITYHIRRSAL MSMEG_1882|M.smegmatis_MC2_155 ETLLETVEKRLPQIPRYRQKVREVTLGLARPVWIDDREFDITYHIRRSAL TH_2686|M.thermoresistible__bu ETLLATVEQRLPQIPRYRQKVRKAPIGLARPVWVDDPDFDITYHVRRSAL MAB_3551c|M.abscessus_ATCC_199 EELLALVESRLPQVPRYRQKVKEIGFGLARPVWLDDVDFDITYHIRRSAL MUL_1313|M.ulcerans_Agy99 QRIRGLLAQRIDLMPPLRWRVREVPFGIDYPVLVQDDTFDLDSHLWESAL MLBr_01244|M.leprae_Br4923 NRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRV : : : . : * :* . * : * *:: *: . : Mb3262c|M.bovis_AF2122/97 PSPGSDEQLHELIARLAARPLDKSRPLWEMYLVEGLEKNRIALYTKSHQA Rv3234c|M.tuberculosis_H37Rv PSPGSDEQLHELIARLAARPLDKSRPLWEMYLVEGLEKNRIALYTKSHQA MMAR_1311|M.marinum_M PSPGSDEQLHELIARLAARPLDKSRPLWEMYLIEGLEKGRVALYTKTHQA MAV_4196|M.avium_104 PSPGSDEQLHELIARLAARPLDKTRPLWEMYLVEGLSKNRLALYTKSHQA Mvan_1764|M.vanbaalenii_PYR-1 PSPGSDAQLHDLVARLGSRPLDKSRPLWEMYLVEGLAKNRIAIYTKSHQA Mflv_4703|M.gilvum_PYR-GCK PSPGSDTQLHDLVARLGSRPLDKTRPLWEMYLAEGLAKNRVAIYTKSHQA MSMEG_1882|M.smegmatis_MC2_155 PSPGSDAQLHDLVARLGSRPLDKTRPLWEMYLVEGLAGNRIAVYTKSHQA TH_2686|M.thermoresistible__bu PSPGSDAQLHELIARLASRPLDKTRPLWEMYLIEGLAKNRLALYTKSHQA MAB_3551c|M.abscessus_ATCC_199 PSPGSDGQLQDLVARLTSRPLDRSRPLWEMYLVEGLSKNRLAIYTKTHQA MUL_1313|M.ulcerans_Agy99 PAPGDDEQLGRAVADIASRPLDRARPLWELHVIHGLAGDRVALVTKLHHS MLBr_01244|M.leprae_Br4923 PDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHA * ** :: : *:* :**** : .** .* *: : :: Mb3262c|M.bovis_AF2122/97 LINGVTALAIGHVIADRTRRPPAFPEDIWVPE-----RDPGTTRLLLRAV Rv3234c|M.tuberculosis_H37Rv LINGVTALAIGHVIADRTRRPPAFPEDIWVPE-----RDPGTTRLLLRAV MMAR_1311|M.marinum_M LINGVTALSLGHVIADRTQRPPPFPEDIWIPE-----RDPGNTRLVMGAI MAV_4196|M.avium_104 LINGMTALEINHVIADRTKRPPAFPEDIWVPE-----RDPGNTRLVLGAI Mvan_1764|M.vanbaalenii_PYR-1 LVNGMTALEIGHVIADRTQKPPAFGEDIWIPG-----REPSDRQLLFGAF Mflv_4703|M.gilvum_PYR-GCK LVNGMAALEIGHVIADRTQKPPEFGEDIWIPG-----REPSDRQLLLGAV MSMEG_1882|M.smegmatis_MC2_155 LVNGMSALEVGHVIADRTQKPPEFGEDIWIPS-----REPTDRQLVLGAI TH_2686|M.thermoresistible__bu LVNGMTAPEIGHVIADRTQKPPQFGEDIWMPG-----REPGTAQLLIGAI MAB_3551c|M.abscessus_ATCC_199 LVDGNSALSLGQVIFDRTARTPDFGEDIWVPE-----HEPSTSELVAGAV MUL_1313|M.ulcerans_Agy99 VIDGVSGMELLGALLDTVSFPDAGPELEKPPTGTAIGNASSDAGLLARAL MLBr_01244|M.leprae_Br4923 ITDGVGSVEMFAEMYDLERDPPSRPRSPQPIP-----QDLSRNDLMLQGI : :* . : : * . . . *: .. Mb3262c|M.bovis_AF2122/97 GDWLVRPGAQLQAVGSAVAGLVTN--------SGQLVETGRKVLDIAR-- Rv3234c|M.tuberculosis_H37Rv GDWLVRPGAQLQAVGSAVAGLVTN--------SGQLVETGRKVLDIAR-- MMAR_1311|M.marinum_M GDWVVGPGAQLQAVGSAIAGLATN--------QSQLVNAGRRILDVAR-- MAV_4196|M.avium_104 GEWLVGPSAQLQAVGSAIGGLVTN--------YGELVDAGRRVFDFVR-- Mvan_1764|M.vanbaalenii_PYR-1 GEWITRPTAQAAALRSAVTDAVTT--------TGQLVELGRRATEVAR-- Mflv_4703|M.gilvum_PYR-GCK GEWITRPTQQAAAVRSAVTETVSS--------TAQIVDLGRRVADVAR-- MSMEG_1882|M.smegmatis_MC2_155 GEWIARPTSQVAALRDTVTEVATN--------AGELAAVGRRIADTVR-- TH_2686|M.thermoresistible__bu GDWLTRPGAQMIAVRDNVLGMATN--------AGELVDAGRRALSVAR-- MAB_3551c|M.abscessus_ATCC_199 SEWLARPGARLEAVRNTVADVASL--------TGEIGELGERMVKVVR-- MUL_1313|M.ulcerans_Agy99 ASLPVQPARMVRGLPPMLRHIDQLPTMRHLPGAAVIAKVADRAERLATRN MLBr_01244|M.leprae_Br4923 NHLPVALAGGVVGGLSGVASVAGR-------AILRPASTVSGVVGYVRSG . . : . Mb3262c|M.bovis_AF2122/97 ------TVARGTAPSSPLNATVSRNRRFTVARASLDDYRTVRARYD-CDV Rv3234c|M.tuberculosis_H37Rv ------TVARGTAPSSPLNATVSRNRRFTVARASLDDYRTVRARYD-CDS MMAR_1311|M.marinum_M ------NVARGTAPSSPLNAPVSRNRRLTVASGRLEDYRTVRARYD-CDV MAV_4196|M.avium_104 ------NVARGTAPSSPLNATVSRHRRFTVASGSLEDYRTVRARYD-CDV Mvan_1764|M.vanbaalenii_PYR-1 ------TVARGAAPSSPLNTTVSRNRRFSVASGSLDEFRAVRARYD-CDV Mflv_4703|M.gilvum_PYR-GCK ------TVARGTAPSSPLNTTVSRNRRFSVASGSLDEFRVVRARYD-CDV MSMEG_1882|M.smegmatis_MC2_155 ------TVARGTAPSSPLNTTVSRNRRFTVADHKLDDYRQVRVRYD-CDI TH_2686|M.thermoresistible__bu ------TVARGTAPSSPLNTRVSRNRRFTVARHRLDDYRKVRARYD-CDV MAB_3551c|M.abscessus_ATCC_199 ------TAARGAAPRGPLNQRVSRSRRFGVVSTKLADYRRVRAKYD-CDV MUL_1313|M.ulcerans_Agy99 KDGRNLQHPRAAAPKVSFGGRISAQRRFAFGSLPLDQIKAAKFAVPGATV MLBr_01244|M.leprae_Br4923 -----IRVLSQAAEPSPLLRQRSLATRTEAIEIQLSDLHKAAKAGD-GSI :* .: * * * : : . Mb3262c|M.bovis_AF2122/97 HDVVLTVIAGALGNWLMSRGEAVAPTATVRAMAPLSVYADDQLDSTGPGQ Rv3234c|M.tuberculosis_H37Rv TTWC---------------------------------------------- MMAR_1311|M.marinum_M HDVVLAVIAGALGNWLMSRGETVSQTATVRAMAPLSVYVEDQLDSSGPGQ MAV_4196|M.avium_104 NDVVLAVIAGALGSWLMSRGVAVSPTATVRAMAPLSVYADGDLDVSGPGQ Mvan_1764|M.vanbaalenii_PYR-1 NDVVLAVVAGALRNWLLSRGEPVRATTTVRAMAPMSVYPDTEIDSSSPGQ Mflv_4703|M.gilvum_PYR-GCK NDVVLAMVAGALRNWLLSRGEPVRATTTVRAMAPMSVYPDAEIDSTGPGQ MSMEG_1882|M.smegmatis_MC2_155 NDVVLAVISGALRNWLLSRGEPVTPSTTVRAMAPLSVYPDEELDSPGPGQ TH_2686|M.thermoresistible__bu NDVVLAVIAGALRNWLLSRGEQVSSTATVRAMAPLSVQSDAELDSTAPGQ MAB_3551c|M.abscessus_ATCC_199 NDVVLATIAGALRNWLMSRGEPVTTASTIRAMVPMSVYRDGDLDVGGEGA MUL_1313|M.ulcerans_Agy99 NDVVVAVCAGALRRRMIARGD--DVATPLVAMVPVSVR-------TGERQ MLBr_01244|M.leprae_Br4923 NDAYLAGLVGALRRYHEALGVSISTLPMAVPVN---------VRTEADVV Mb3262c|M.bovis_AF2122/97 AISQVTPFLVDLPVGEGNAVVRLSQIAHATESNPTAASLVDARTIVTLSG Rv3234c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1311|M.marinum_M QISQVTPFLIDLPVGERNAVVRLSQVAHATESNPTAASLVDARTIVTLSG MAV_4196|M.avium_104 AISQVMPFLVDLPVGEPNAVVRLSQIAHATESNPTAAHLVDARTIVTLSG Mvan_1764|M.vanbaalenii_PYR-1 AISEVVPFLVDLPVGEANPVVRLSQISHATETHPTAPSLVDARTIITLSG Mflv_4703|M.gilvum_PYR-GCK AISEVAPFLVDLPVGESNPVVRLSQISHATESHPTAPSLVDARTIVTLSG MSMEG_1882|M.smegmatis_MC2_155 AISEVSPFLVDLPVGEGNAVVRLSHITHANESNSWAVSLVDARTIVTLSG TH_2686|M.thermoresistible__bu AVSDVVPFLIDLPVGERNPVVRLSQISHATETHPTASSLVDARTIVTLTG MAB_3551c|M.abscessus_ATCC_199 ATTEVSPFLVDLPVGEGNTVVRLSQIAHATESHSAAFSLVDVPNMAALSG MUL_1313|M.ulcerans_Agy99 YGNQISSMIVPIPTDQADARARLISAHQVMRAAKERHRAIPAKLLTEANH MLBr_01244|M.leprae_Br4923 GSNRFVGVTLAAPLGTNDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMT Mb3262c|M.bovis_AF2122/97 LAPATLHAMGVRVAT-----SFSARLFNLLITNAPGTQSQMYIAGTKLLE Rv3234c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1311|M.marinum_M FAPPTLHAMGIRVATSFP--SFSKRTFNLLITNAPGAQSQMYVAGAKLLE MAV_4196|M.avium_104 FAPPTLHAMGIRVATSFP--SFSKRTFNLLITNAPGAQSQMYVAGTKLLE Mvan_1764|M.vanbaalenii_PYR-1 FAPPTLHAMGIRVAT-----SFSARLFNLLITNAPGAQNQMYIAGTKLLE Mflv_4703|M.gilvum_PYR-GCK FAPPTLHAMGIRVAT-----SFSARQFNLLITNVPGAQSQMYIAGTKLLE MSMEG_1882|M.smegmatis_MC2_155 FAPPTLHAMGIRVAT-----GFSARLFNLLITNVPGPQKQMYVAGTKLLE TH_2686|M.thermoresistible__bu FAPATLHAMGVRVAT-----NFSARQFNLLITNVPGAQKQMYIAGTKMLE MAB_3551c|M.abscessus_ATCC_199 FVPPTLHALAARVAS-----TLPNRLFNLLVTNVPGPQAPMYLGGARLAE MUL_1313|M.ulcerans_Agy99 TVPPALLTRAARVISMTTGSGWIRPPFNVTISNIPGSPDPLYCAGARVVS MLBr_01244|M.leprae_Br4923 VLPASVLDFIVDSVAS----------SDVNASNIPAYPGDTYFAGAKILR Mb3262c|M.bovis_AF2122/97 TYSVPPLLHNQALAISVTSYNGMLYFGINADRDAMSDVDLLPGLLSQALD Rv3234c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1311|M.marinum_M AYAVPPLLHNQALAISVTSYNGMLYFGINADRDAMSDVELLPALLAQSLE MAV_4196|M.avium_104 TYSVPPLLHNQALAIGVTSYNGMLYYGINADREAMSDVDLLPALLNQALE Mvan_1764|M.vanbaalenii_PYR-1 TYAVPPLLHNQALAIGVTSYNGMLYFGINADRDAMSDVDMLPSLLRESLD Mflv_4703|M.gilvum_PYR-GCK TYSVPPLLHNQTLAIGVTSYNGMLYFGINADRDAMSDVDMLPSLLREALD MSMEG_1882|M.smegmatis_MC2_155 TYAVPPLLHNQVLAIGVTSYNGRLYFGINADRDAMSDVDVFRSLLDESLE TH_2686|M.thermoresistible__bu SYSVPPLLRNQVLAVAVTSYHGMLYYGVNADRDAMSDVEVLPSLLSESLD MAB_3551c|M.abscessus_ATCC_199 IYPVPPLLRNQVLSIGLTSYNGTVYYGINADREAMPDADMLPLLITEALD MUL_1313|M.ulcerans_Agy99 QHPVNVLLDGMGLSITLLSYQDRLDFGLTADRELLPDVWHLADELAAELS MLBr_01244|M.leprae_Br4923 QYGIGPRPG-VAMMAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFD Mb3262c|M.bovis_AF2122/97 ELLEASR--------------------------- Rv3234c|M.tuberculosis_H37Rv ---------------------------------- MMAR_1311|M.marinum_M ELLEASR--------------------------- MAV_4196|M.avium_104 ELVEAARS-------------------------- Mvan_1764|M.vanbaalenii_PYR-1 ELVEAAR--------------------------- Mflv_4703|M.gilvum_PYR-GCK ELVEAAR--------------------------- MSMEG_1882|M.smegmatis_MC2_155 ELIDAAK--------------------------- TH_2686|M.thermoresistible__bu ELLEAAQ--------------------------- MAB_3551c|M.abscessus_ATCC_199 ELLEAAQ--------------------------- MUL_1313|M.ulcerans_Agy99 ALAAEVGAPRNPVADGAPTSTTGRPTAKPGAIPR MLBr_01244|M.leprae_Br4923 EVLALAGDPTPHAVPASFAARSSGSPAGWLSSS-