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SDPRPARAVVVGIDGSRAATHAALWAVDEAVNRDIPLRLVYVIDPSQLSAAGEGGGQSAARAALHDASRK VEATGQPVKIETEVLCGRPLTKLMQESRSAAMLCVGSVGLDHVRGRRGSVAATLAGSALCPVAVIHPSPA EPATTSQVSAVVAEVDNGVVLRHAFEEARLRGVPLRAVAVHAAETPDDVEQGSRLAHVHLSRRLAHWTRL YPEVRVDRAIAGGSACRHLAANAKPGQLFVADSHSAHELCGAYQPGCAVLTVRSANL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3134c | - | - | 100% (268) | hypothetical protein Rv3134c |
| M. tuberculosis H37Rv | Rv2028c | - | 1e-41 | 40.66% (273) | hypothetical protein Rv2028c |
| M. tuberculosis H37Rv | Rv2624c | - | 4e-33 | 36.16% (271) | hypothetical protein Rv2624c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3158c | - | 1e-151 | 100.00% (268) | hypothetical protein Mb3158c |
| M. gilvum PYR-GCK | Mflv_3846 | - | 4e-38 | 40.89% (247) | UspA domain-containing protein |
| M. leprae Br4923 | MLBr_01390 | - | 5e-06 | 30.34% (145) | hypothetical protein MLBr_01390 |
| M. abscessus ATCC 19977 | MAB_3904 | - | 1e-36 | 38.89% (270) | hypothetical protein MAB_3904 |
| M. marinum M | MMAR_1515 | - | 1e-93 | 67.56% (262) | hypothetical protein MMAR_1515 |
| M. avium 104 | MAV_4010 | - | 3e-68 | 53.90% (269) | hypothetical protein MAV_4010 |
| M. smegmatis MC2 155 | MSMEG_5245 | - | 3e-35 | 35.38% (277) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 7e-19 | 31.25% (272) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_2424 | - | 2e-93 | 67.18% (262) | hypothetical protein MUL_2424 |
| M. vanbaalenii PYR-1 | Mvan_2549 | - | 2e-39 | 41.49% (241) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3134c|M.tuberculosis_H37Rv -MSDPRPARAVVVGIDGSRAATHAALWAVDEA-VNRDIPLRLVYVIDPSQ
Mb3158c|M.bovis_AF2122/97 -MSDPRPARAVVVGIDGSRAATHAALWAVDEA-VNRDIPLRLVYVIDPSQ
MMAR_1515|M.marinum_M -MSN-QAAPAIVVGIDGSRASTHAAVWAVDEA-VSRDIPVRLVYIIDPAQ
MUL_2424|M.ulcerans_Agy99 -MSN-QAAPAIVVGIDGSRASTHAAVWAVDEA-VSRDIPVRLVYIIDPAQ
MAV_4010|M.avium_104 -MSTAYPAPAIVVGVDGSRAAMHAAVWAIDEA-VGRDIPLRLVYVIDPHG
Mflv_3846|M.gilvum_PYR-GCK MLDATFV-PCIVVGIDGSPAAVDAALWAVDQA-VDLDIPLRLVYVIDADN
Mvan_2549|M.vanbaalenii_PYR-1 MLEPS---ACIVVGIDGSPAGVDAALWAIEQA-VDHDMPLRLVYVVDAGE
MAB_3904|M.abscessus_ATCC_1997 MNEIRTPGPAVLVGIDGSRSAVRAALWAVDEA-LHRELPLRLVHVTPQTE
MSMEG_5245|M.smegmatis_MC2_155 MSIAR----PVIVGIDGSQPAVDAAIWAVKEA-LSRGVPLRLIYAVHPDD
TH_2494|M.thermoresistible__bu -VSSTAAYEGIVVGVDGSAASADAVRWAARSA-ALRNLQLTLVHVMTATS
MLBr_01390|M.leprae_Br4923 ----MGAYQTVVVGTDGSDSSLRAVDRAGKIAGSDAKLIIASAYLPQHDN
::** *** .. *. * * : : :
Rv3134c|M.tuberculosis_H37Rv LSAA-----------------GEGGGQSAARAALHDASRKVEATGQP---
Mb3158c|M.bovis_AF2122/97 LSAA-----------------GEGGGQSAARAALHDASRKVEATGQP---
MMAR_1515|M.marinum_M APAS-----------------DRDGRQSAARAALFDVQRAVEATGQP---
MUL_2424|M.ulcerans_Agy99 APAG-----------------DRDGRQSSARAALFDVQRAVEATGQP---
MAV_4010|M.avium_104 APGGH----------------GPDTRLAAARAALADAHRAVDAFAQP---
Mflv_3846|M.gilvum_PYR-GCK EDAVDPH--------------DQARQLATAEMAVRYALTALESTDQP---
Mvan_2549|M.vanbaalenii_PYR-1 HGTVDPH--------------DQARSIATAEVALRYALAAVESVERP---
MAB_3904|M.abscessus_ATCC_1997 FPEFS----------------DER---SPAGTAVRHAFRQIGATHKP---
MSMEG_5245|M.smegmatis_MC2_155 -NGADHE--------------NSARALATAEVAIRQACVAVESTEQP---
TH_2494|M.thermoresistible__bu IGAPLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGPA
MLBr_01390|M.leprae_Br4923 ARAFDILK-------------DESYKVTGTAPIYEILHDAKERAHAAG--
. .
Rv3134c|M.tuberculosis_H37Rv ----VKIETEVLCGRPLTKLMQESR--SAAMLCVGSVGLDHVRGR-RGSV
Mb3158c|M.bovis_AF2122/97 ----VKIETEVLCGRPLTKLMQESR--SAAMLCVGSVGLDHVRGR-RGSV
MMAR_1515|M.marinum_M ----VKIETEILWGRPLTKLLEESR--TAVMVCVGSIGLNHARRG-EGSV
MUL_2424|M.ulcerans_Agy99 ----VKIETEILWGRPLTKLLEESR--TAVMVCVGSIGLNHARRG-EGSV
MAV_4010|M.avium_104 ----VKVETEILWGNTAFKLLEQSR--SAVMLCVGQIGLNHACHG-GPAI
Mflv_3846|M.gilvum_PYR-GCK ----VKIEVEILRGRPVQTLLEAAR--SAVLLCLGARGLKHSTQGRIGST
Mvan_2549|M.vanbaalenii_PYR-1 ----VKIEVEILQGRPVQTLLEAAR--SAAMLCIGARGLKHSTQGRIGST
MAB_3904|M.abscessus_ATCC_1997 ----VKVEAEIRHGRVADVLLDASR--SAVMLCVGAIGISGADTRKVGST
MSMEG_5245|M.smegmatis_MC2_155 ----VQIELEVVQDKPIEALIAASQ--NTPLLCVGASGLTQAGRGGIGSV
TH_2494|M.thermoresistible__bu GDDAVRVVTGVVRAAPVPTLVDASK--QAKLVAVGSRGQGPLRRVLLGSV
MLBr_01390|M.leprae_Br4923 ---AKNVEERPVVGAPVDALVNLAEKTNADLLVVGNVGLSTIAGRLLGSV
.: *: :. : :: :* * :
Rv3134c|M.tuberculosis_H37Rv AATLAGSALCPVAVIHP-SPAEPATTS--QVSAVVAEVDNGVVLRHAFEE
Mb3158c|M.bovis_AF2122/97 AATLAGSALCPVAVIHP-SPAEPATTS--QVSAVVAEVDNGVVLRHAFEE
MMAR_1515|M.marinum_M AGTLAGSALCPVAVIQ--SPAGAAGAP--KVGEVVAEVDNGSVLRHAFEE
MUL_2424|M.ulcerans_Agy99 AGTLAGSALCPVAVIQ--SPAGAAGAP--KVGEVVAEVDNGSVLRHAFEE
MAV_4010|M.avium_104 ATSLVRSALCPVAVVQQ-APSLPA-AA--RVSGVVAEVDNGTVLRHAFEE
Mflv_3846|M.gilvum_PYR-GCK AGAVSTSAHCPVAVVRAHRPHRRPDRA--VVIEITDNAGGGAVLERGLDE
Mvan_2549|M.vanbaalenii_PYR-1 AVALATSALCPVAIVRSHRPHRR-DRA--VVIEFTD----GAVMQRGLAE
MAB_3904|M.abscessus_ATCC_1997 AAEVLRSVRCPVAVIRDDPSSLRGTSA--VVVEIDESHESVTPLELAAHE
MSMEG_5245|M.smegmatis_MC2_155 ASAVLRSAQCPVAVVATPGKGRR------ILVEFDGRPSASTALQTGVDE
TH_2494|M.thermoresistible__bu SSGLVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEE
MLBr_01390|M.leprae_Br4923 PANVSRRAKIDVLIVHTTH-------------------------------
. : . * ::
Rv3134c|M.tuberculosis_H37Rv ARLRGVPLRAVAVHAAETP-------DDVEQGSRLAHVHLSRRLAHWTRL
Mb3158c|M.bovis_AF2122/97 ARLRGVPLRAVAVHAAETP-------DDVEQGSRLAHVHLSRRLAHWTRL
MMAR_1515|M.marinum_M ARLRNVPLRAISSRVATG--------HGSEDGNRLATAQLTRRLTRWTRL
MUL_2424|M.ulcerans_Agy99 ARLRNVPLRAISSRVATD--------HGSEDGNRLATAQLTRRLTRWTRL
MAV_4010|M.avium_104 ARLRGVGLCAV--------------------GNPSARVELERRLARWMRL
Mflv_3846|M.gilvum_PYR-GCK ARRRGAPVRVLTSAR------------SQLDV----TGRWERRLAEWRRR
Mvan_2549|M.vanbaalenii_PYR-1 AKRRRVPARVLIPAR------------THPDARSHASAAWERRLAEWQRS
MAB_3904|M.abscessus_ATCC_1997 ARLRAAPLRVLLRHRPISLSGQRVATLTRVDRR-VAAVHVERRLAPLRVR
MSMEG_5245|M.smegmatis_MC2_155 ARLRDAPLSVMTTWQHR--HRELYEEKVAEERNRLAQSQLDRRMTRYRKR
TH_2494|M.thermoresistible__bu ASFRGVDLIALHAWSDADIADIP--TLELSAVQQSAERVLSERLAGFRER
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Rv3134c|M.tuberculosis_H37Rv YPEVRVDRAIAGGSACRHLAANAKPGQLFVADSHS---------AHELCG
Mb3158c|M.bovis_AF2122/97 YPEVRVDRAIAGGSACRHLAANAKPGQLFVADSHS---------AHELCG
MMAR_1515|M.marinum_M YPDVRVESAIIAGHACRYMAANAKPDELYVTDSH----------AAQVCS
MUL_2424|M.ulcerans_Agy99 YPDVRVESAIIAGHACRYMAANAKPDELYVTDSH----------AAQVCS
MAV_4010|M.avium_104 YPDVQAESAVLTGGVEQHLRADHRAGRLLVTDAYR---------AEALC-
Mflv_3846|M.gilvum_PYR-GCK YPDLDISAVRARDGLFDYLAAHGDGLQLLVAGRNRPGGVAPLVGTPGNAA
Mvan_2549|M.vanbaalenii_PYR-1 YPDVEIVPVSERIDTLDYLAAHGDDVQLVVAGRNRPGGVAALVGPPGNAA
MAB_3904|M.abscessus_ATCC_1997 YPDLDIRALDPVGGTLDYLERHGHTVQLVVVGAGDAAHVQELVGPNGCGV
MSMEG_5245|M.smegmatis_MC2_155 YPELDLELITDHGNTADYVAANPQTVQLIVVGAERFNRAGDVTDPAALGA
TH_2494|M.thermoresistible__bu YPDVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTGMLLGSVSRA
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Rv3134c|M.tuberculosis_H37Rv AYQPGCAVLTVRSANL-
Mb3158c|M.bovis_AF2122/97 AYQPGCAVLTVRSANL-
MMAR_1515|M.marinum_M VYGAGCSVLTVRSGNL-
MUL_2424|M.ulcerans_Agy99 VYGAGCSVLTVRSGNL-
MAV_4010|M.avium_104 --HAGHSVLAVRCGNL-
Mflv_3846|M.gilvum_PYR-GCK LRDTDCSILVCEPPNAL
Mvan_2549|M.vanbaalenii_PYR-1 LRDTDCSILVCEPHNVL
MAB_3904|M.abscessus_ATCC_1997 LGRTHCSVLIAERQRLL
MSMEG_5245|M.smegmatis_MC2_155 LVDAGCSLLTCDRQQRL
TH_2494|M.thermoresistible__bu VVNAVTTPVIVAR----
MLBr_01390|M.leprae_Br4923 -----------------