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STAYPAPAIVVGVDGSRAAMHAAVWAIDEAVGRDIPLRLVYVIDPHGAPGGHGPDTRLAAARAALADAHR AVDAFAQPVKVETEILWGNTAFKLLEQSRSAVMLCVGQIGLNHACHGGPAIATSLVRSALCPVAVVQQAP SLPAAARVSGVVAEVDNGTVLRHAFEEARLRGVGLCAVGNPSARVELERRLARWMRLYPDVQAESAVLTG GVEQHLRADHRAGRLLVTDAYRAEALCHAGHSVLAVRCGNL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4010 | - | - | 100% (252) | hypothetical protein MAV_4010 |
| M. avium 104 | MAV_2506 | - | 3e-13 | 28.12% (256) | universal stress protein family protein |
| M. avium 104 | MAV_2507 | - | 5e-13 | 28.12% (256) | universal stress protein family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3158c | - | 2e-68 | 53.90% (269) | hypothetical protein Mb3158c |
| M. gilvum PYR-GCK | Mflv_3846 | - | 6e-36 | 40.85% (235) | UspA domain-containing protein |
| M. tuberculosis H37Rv | Rv3134c | - | 3e-68 | 53.90% (269) | hypothetical protein Rv3134c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3904 | - | 1e-31 | 38.80% (250) | hypothetical protein MAB_3904 |
| M. marinum M | MMAR_1515 | - | 4e-73 | 57.31% (260) | hypothetical protein MMAR_1515 |
| M. smegmatis MC2 155 | MSMEG_5245 | - | 3e-29 | 33.07% (257) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 4e-13 | 29.59% (267) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_2424 | - | 1e-73 | 57.31% (260) | hypothetical protein MUL_2424 |
| M. vanbaalenii PYR-1 | Mvan_2549 | - | 4e-36 | 44.50% (209) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3158c|M.bovis_AF2122/97 -MSDPRPARAVVVGIDGSRAATHAALWAVDEAVNRDIPLRLVYVIDPSQL
Rv3134c|M.tuberculosis_H37Rv -MSDPRPARAVVVGIDGSRAATHAALWAVDEAVNRDIPLRLVYVIDPSQL
MMAR_1515|M.marinum_M -MSN-QAAPAIVVGIDGSRASTHAAVWAVDEAVSRDIPVRLVYIIDPAQA
MUL_2424|M.ulcerans_Agy99 -MSN-QAAPAIVVGIDGSRASTHAAVWAVDEAVSRDIPVRLVYIIDPAQA
MAV_4010|M.avium_104 -MSTAYPAPAIVVGVDGSRAAMHAAVWAIDEAVGRDIPLRLVYVIDPHGA
MAB_3904|M.abscessus_ATCC_1997 MNEIRTPGPAVLVGIDGSRSAVRAALWAVDEALHRELPLRLVH-VTPQTE
MSMEG_5245|M.smegmatis_MC2_155 MSIARP----VIVGIDGSQPAVDAAIWAVKEALSRGVPLRLIYAVHPDDN
Mflv_3846|M.gilvum_PYR-GCK -MLDATFVPCIVVGIDGSPAAVDAALWAVDQAVDLDIPLRLVYVIDADNE
Mvan_2549|M.vanbaalenii_PYR-1 -MLEPS--ACIVVGIDGSPAGVDAALWAIEQAVDHDMPLRLVYVVDAGEH
TH_2494|M.thermoresistible__bu -VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRNLQLTLVHVMTATSI
::**:*** .. *. ** .* : : *:: : .
Mb3158c|M.bovis_AF2122/97 SAA----------------GEGGG--QSAARAALHDASRKVEATG-----
Rv3134c|M.tuberculosis_H37Rv SAA----------------GEGGG--QSAARAALHDASRKVEATG-----
MMAR_1515|M.marinum_M PAS----------------DRDGR--QSAARAALFDVQRAVEATG-----
MUL_2424|M.ulcerans_Agy99 PAG----------------DRDGR--QSSARAALFDVQRAVEATG-----
MAV_4010|M.avium_104 PGGH---------------GPDTR--LAAARAALADAHRAVDAFA-----
MAB_3904|M.abscessus_ATCC_1997 -FPE---------------FSDER---SPAGTAVRHAFRQIGATH-----
MSMEG_5245|M.smegmatis_MC2_155 -GAD---------------HENSARALATAEVAIRQACVAVESTE-----
Mflv_3846|M.gilvum_PYR-GCK DAVD---------------PHDQARQLATAEMAVRYALTALESTD-----
Mvan_2549|M.vanbaalenii_PYR-1 GTVD---------------PHDQARSIATAEVALRYALAAVESVE-----
TH_2494|M.thermoresistible__bu GAPLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGPAG
: : . :
Mb3158c|M.bovis_AF2122/97 -QPVKIETEVLCGRPLTKLMQESRSAAMLCVGSVGLDHVRGR-RGSVAAT
Rv3134c|M.tuberculosis_H37Rv -QPVKIETEVLCGRPLTKLMQESRSAAMLCVGSVGLDHVRGR-RGSVAAT
MMAR_1515|M.marinum_M -QPVKIETEILWGRPLTKLLEESRTAVMVCVGSIGLNHARRG-EGSVAGT
MUL_2424|M.ulcerans_Agy99 -QPVKIETEILWGRPLTKLLEESRTAVMVCVGSIGLNHARRG-EGSVAGT
MAV_4010|M.avium_104 -QPVKVETEILWGNTAFKLLEQSRSAVMLCVGQIGLNHACHG-GPAIATS
MAB_3904|M.abscessus_ATCC_1997 -KPVKVEAEIRHGRVADVLLDASRSAVMLCVGAIGISGADTRKVGSTAAE
MSMEG_5245|M.smegmatis_MC2_155 -QPVQIELEVVQDKPIEALIAASQNTPLLCVGASGLTQAGRGGIGSVASA
Mflv_3846|M.gilvum_PYR-GCK -QPVKIEVEILRGRPVQTLLEAARSAVLLCLGARGLKHSTQGRIGSTAGA
Mvan_2549|M.vanbaalenii_PYR-1 -RPVKIEVEILQGRPVQTLLEAARSAAMLCIGARGLKHSTQGRIGSTAVA
TH_2494|M.thermoresistible__bu DDAVRVVTGVVRAAPVPTLVDASKQAKLVAVGSRGQGPLRRVLLGSVSSG
.*:: : *: :: : ::.:* * : :
Mb3158c|M.bovis_AF2122/97 LAGSALCPVAVIHP-SPAEPATTS--QVSAVVAEVDNGVVLRHAFEEARL
Rv3134c|M.tuberculosis_H37Rv LAGSALCPVAVIHP-SPAEPATTS--QVSAVVAEVDNGVVLRHAFEEARL
MMAR_1515|M.marinum_M LAGSALCPVAVIQ--SPAGAAGAP--KVGEVVAEVDNGSVLRHAFEEARL
MUL_2424|M.ulcerans_Agy99 LAGSALCPVAVIQ--SPAGAAGAP--KVGEVVAEVDNGSVLRHAFEEARL
MAV_4010|M.avium_104 LVRSALCPVAVVQQ-APSLPA-AA--RVSGVVAEVDNGTVLRHAFEEARL
MAB_3904|M.abscessus_ATCC_1997 VLRSVRCPVAVIRDDPSSLRGTSA--VVVEIDESHESVTPLELAAHEARL
MSMEG_5245|M.smegmatis_MC2_155 VLRSAQCPVAVVATPGKGRR------ILVEFDGRPSASTALQTGVDEARL
Mflv_3846|M.gilvum_PYR-GCK VSTSAHCPVAVVRAHRPHRRPDRA--VVIEITDNAGGGAVLERGLDEARR
Mvan_2549|M.vanbaalenii_PYR-1 LATSALCPVAIVRSHRPHRR-DRA--VVIEFTD----GAVMQRGLAEAKR
TH_2494|M.thermoresistible__bu LVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEEASF
: . ****:: : . . **
Mb3158c|M.bovis_AF2122/97 RGVPLRAVAVHAAETPDDVEQ--------GSRLAHVHLSRRLAHWTRLYP
Rv3134c|M.tuberculosis_H37Rv RGVPLRAVAVHAAETPDDVEQ--------GSRLAHVHLSRRLAHWTRLYP
MMAR_1515|M.marinum_M RNVPLRAISSRVATG-HGSED--------GNRLATAQLTRRLTRWTRLYP
MUL_2424|M.ulcerans_Agy99 RNVPLRAISSRVATD-HGSED--------GNRLATAQLTRRLTRWTRLYP
MAV_4010|M.avium_104 RGVGLCAV---------------------GNPSARVELERRLARWMRLYP
MAB_3904|M.abscessus_ATCC_1997 RAAPLRVL--LRHRPISLSGQRVATLTRVDRRVAAVHVERRLAPLRVRYP
MSMEG_5245|M.smegmatis_MC2_155 RDAPLSVMTTWQHRHRELYEEKVAEER---NRLAQSQLDRRMTRYRKRYP
Mflv_3846|M.gilvum_PYR-GCK RGAPVRVLTSARSQLDV-----------------TGRWERRLAEWRRRYP
Mvan_2549|M.vanbaalenii_PYR-1 RRVPARVLIPARTHPDARSH-------------ASAAWERRLAEWQRSYP
TH_2494|M.thermoresistible__bu RGVDLIALHAWSDADIADIPTLELS---AVQQSAERVLSERLAGFRERYP
* . .: .*:: **
Mb3158c|M.bovis_AF2122/97 EVRVDRAIAGGSACRHLAANAKPGQLFVADSHS---------AHELCGAY
Rv3134c|M.tuberculosis_H37Rv EVRVDRAIAGGSACRHLAANAKPGQLFVADSHS---------AHELCGAY
MMAR_1515|M.marinum_M DVRVESAIIAGHACRYMAANAKPDELYVTDSH----------AAQVCSVY
MUL_2424|M.ulcerans_Agy99 DVRVESAIIAGHACRYMAANAKPDELYVTDSH----------AAQVCSVY
MAV_4010|M.avium_104 DVQAESAVLTGGVEQHLRADHRAGRLLVTDAYR---------AEALC---
MAB_3904|M.abscessus_ATCC_1997 DLDIRALDPVGGTLDYLERHGHTVQLVVVGAGDAAHVQELVGPNGCGVLG
MSMEG_5245|M.smegmatis_MC2_155 ELDLELITDHGNTADYVAANPQTVQLIVVGAERFNRAGDVTDPAALGALV
Mflv_3846|M.gilvum_PYR-GCK DLDISAVRARDGLFDYLAAHGDGLQLLVAGRNRPGGVAPLVGTPGNAALR
Mvan_2549|M.vanbaalenii_PYR-1 DVEIVPVSERIDTLDYLAAHGDDVQLVVAGRNRPGGVAALVGPPGNAALR
TH_2494|M.thermoresistible__bu DVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTGMLLGSVSRAVV
:: :: .* *..
Mb3158c|M.bovis_AF2122/97 QPGCAVLTVRSANL-
Rv3134c|M.tuberculosis_H37Rv QPGCAVLTVRSANL-
MMAR_1515|M.marinum_M GAGCSVLTVRSGNL-
MUL_2424|M.ulcerans_Agy99 GAGCSVLTVRSGNL-
MAV_4010|M.avium_104 HAGHSVLAVRCGNL-
MAB_3904|M.abscessus_ATCC_1997 RTHCSVLIAERQRLL
MSMEG_5245|M.smegmatis_MC2_155 DAGCSLLTCDRQQRL
Mflv_3846|M.gilvum_PYR-GCK DTDCSILVCEPPNAL
Mvan_2549|M.vanbaalenii_PYR-1 DTDCSILVCEPHNVL
TH_2494|M.thermoresistible__bu NAVTTPVIVAR----
. : :