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MLDATFVPCIVVGIDGSPAAVDAALWAVDQAVDLDIPLRLVYVIDADNEDAVDPHDQARQLATAEMAVRY ALTALESTDQPVKIEVEILRGRPVQTLLEAARSAVLLCLGARGLKHSTQGRIGSTAGAVSTSAHCPVAVV RAHRPHRRPDRAVVIEITDNAGGGAVLERGLDEARRRGAPVRVLTSARSQLDVTGRWERRLAEWRRRYPD LDISAVRARDGLFDYLAAHGDGLQLLVAGRNRPGGVAPLVGTPGNAALRDTDCSILVCEPPNAL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3846 | - | - | 100% (274) | UspA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_4995 | - | 1e-38 | 35.87% (276) | UspA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_4991 | - | 4e-34 | 34.75% (259) | UspA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2053c | - | 2e-58 | 46.24% (266) | hypothetical protein Mb2053c |
| M. tuberculosis H37Rv | Rv2028c | - | 2e-58 | 46.24% (266) | hypothetical protein Rv2028c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3904 | - | 5e-47 | 41.37% (278) | hypothetical protein MAB_3904 |
| M. marinum M | MMAR_2076 | - | 9e-45 | 37.16% (261) | hypothetical protein MMAR_2076 |
| M. avium 104 | MAV_4010 | - | 6e-36 | 40.85% (235) | hypothetical protein MAV_4010 |
| M. smegmatis MC2 155 | MSMEG_5245 | - | 3e-51 | 39.64% (280) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 1e-20 | 29.29% (297) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_2424 | - | 5e-39 | 41.00% (239) | hypothetical protein MUL_2424 |
| M. vanbaalenii PYR-1 | Mvan_2549 | - | 1e-106 | 72.22% (270) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3846|M.gilvum_PYR-GCK MLDATFV-PCIVVGIDGSPAAVDAALWAVDQAVDLDIPLRLVYVIDADNE
Mvan_2549|M.vanbaalenii_PYR-1 MLEPS---ACIVVGIDGSPAGVDAALWAIEQAVDHDMPLRLVYVVDAGEH
Mb2053c|M.bovis_AF2122/97 MNQSHKP-PSIVVGIDGSKPAVQAALWAVDEAASRDIPLRLLYAIEPDDP
Rv2028c|M.tuberculosis_H37Rv MNQSHKP-PSIVVGIDGSKPAVQAALWAVDEAASRDIPLRLLYAIEPDDP
MAB_3904|M.abscessus_ATCC_1997 MNEIRTPGPAVLVGIDGSRSAVRAALWAVDEALHRELPLRLVH-VTPQTE
MSMEG_5245|M.smegmatis_MC2_155 MSIARP----VIVGIDGSQPAVDAAIWAVKEALSRGVPLRLIYAVHPDDN
MAV_4010|M.avium_104 -MSTAYPAPAIVVGVDGSRAAMHAAVWAIDEAVGRDIPLRLVYVIDPHGA
MUL_2424|M.ulcerans_Agy99 -MSN-QAAPAIVVGIDGSRASTHAAVWAVDEAVSRDIPVRLVYIIDPAQA
MMAR_2076|M.marinum_M -------MKPVIVGIDGSPAGITAVLWATAEAVSAGVPLRLISVLKTAHS
TH_2494|M.thermoresistible__bu -VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRNLQLTLVHVMTATSI
::**:*** .. *. ** .* : : *: : .
Mflv_3846|M.gilvum_PYR-GCK DA---------------VDPHDQARQLATAEMAVRYALTALEST------
Mvan_2549|M.vanbaalenii_PYR-1 GT---------------VDPHDQARSIATAEVALRYALAAVESV------
Mb2053c|M.bovis_AF2122/97 GY---------------AAHGAAARKLAAAENAVRYAFTAVEAA------
Rv2028c|M.tuberculosis_H37Rv GY---------------AAHGAAARKLAAAENAVRYAFTAVEAA------
MAB_3904|M.abscessus_ATCC_1997 -F---------------PEFSDER---SPAGTAVRHAFRQIGAT------
MSMEG_5245|M.smegmatis_MC2_155 -G---------------ADHENSARALATAEVAIRQACVAVEST------
MAV_4010|M.avium_104 PG---------------GHGPDTRL--AAARAALADAHRAVDAF------
MUL_2424|M.ulcerans_Agy99 PA---------------GD-RDGRQ--SSARAALFDVQRAVEAT------
MMAR_2076|M.marinum_M ------------------SPEEYEHDLAHAETSLRAAQSAIEAT------
TH_2494|M.thermoresistible__bu GAPLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGPAG
: : . :
Mflv_3846|M.gilvum_PYR-GCK DQPVKIEVEILRGRPVQTLLEAARSAVLLCLGARGLKHSTQGRIGSTAGA
Mvan_2549|M.vanbaalenii_PYR-1 ERPVKIEVEILQGRPVQTLLEAARSAAMLCIGARGLKHSTQGRIGSTAVA
Mb2053c|M.bovis_AF2122/97 DRPVKVEVEITQERPVTSLIRASAAAALVCVGAIGVHHFRPERVGSTAAA
Rv2028c|M.tuberculosis_H37Rv DRPVKVEVEITQERPVTSLIRASAAAALVCVGAIGVHHFRPERVGSTAAA
MAB_3904|M.abscessus_ATCC_1997 HKPVKVEAEIRHGRVADVLLDASRSAVMLCVGAIGISGADTRKVGSTAAE
MSMEG_5245|M.smegmatis_MC2_155 EQPVQIELEVVQDKPIEALIAASQNTPLLCVGASGLTQAGRGGIGSVASA
MAV_4010|M.avium_104 AQPVKVETEILWGNTAFKLLEQSRSAVMLCVGQIGLNHACHG-GPAIATS
MUL_2424|M.ulcerans_Agy99 GQPVKIETEILWGRPLTKLLEESRTAVMVCVGSIGLNHARRG-EGSVAGT
MMAR_2076|M.marinum_M AAPVKVETDTPRGPAGAVLVEASRDAELVCVGSVGIGRYARAILGSTATE
TH_2494|M.thermoresistible__bu DDAVRVVTGVVRAAPVPTLVDASKQAKLVAVGSRGQGPLRRVLLGSVSSG
.*:: *: : : ::.:* * : :
Mflv_3846|M.gilvum_PYR-GCK VSTSAHCPVAVVR-AHR-PHRRPDRAVVIEITDNAGGGAVLERGLDEARR
Mvan_2549|M.vanbaalenii_PYR-1 LATSALCPVAIVR-SHR-PHRR-DRAVVIEFTD----GAVMQRGLAEAKR
Mb2053c|M.bovis_AF2122/97 LALSAQCPVAIVR-PHRVPIGRDAAWIVVEADGSSDIGVLLGAVMAEARL
Rv2028c|M.tuberculosis_H37Rv LALSAQCPVAIVR-PHRVPIGRDAAWIVVEADGSSDIGVLLGAVMAEARL
MAB_3904|M.abscessus_ATCC_1997 VLRSVRCPVAVIR-DDP-SSLRGTSAVVVEIDESHESVTPLELAAHEARL
MSMEG_5245|M.smegmatis_MC2_155 VLRSAQCPVAVVA-TPG-KGRR----ILVEFDGRPSASTALQTGVDEARL
MAV_4010|M.avium_104 LVRSALCPVAVVQQAPSLPAAARVSGVVAEVDN----GTVLRHAFEEARL
MUL_2424|M.ulcerans_Agy99 LAGSALCPVAVIQSPAGAAGAPKVGEVVAEVDN----GSVLRHAFEEARL
MMAR_2076|M.marinum_M LAEKAHCPVAVIR-SNSDQPPPDINWIVVRVTDAPDNDAVIEYAAHEARL
TH_2494|M.thermoresistible__bu LVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEEASF
: . ****:: :: **
Mflv_3846|M.gilvum_PYR-GCK RGAPVRVLTSARS-QLDV----------------TGRWERRLAEWRRRYP
Mvan_2549|M.vanbaalenii_PYR-1 RRVPARVLIPART-HPDARSH------------ASAAWERRLAEWQRSYP
Mb2053c|M.bovis_AF2122/97 RDSPVRVVTCRQSGVGDTGDD------------VRASLDRWLARWQPRYP
Rv2028c|M.tuberculosis_H37Rv RDSPVRVVTCRQSGVGDTGDD------------VRASLDRWLARWQPRYP
MAB_3904|M.abscessus_ATCC_1997 RAAPLRVL--LRHRPISLSGQRVATLTRVDRRVAAVHVERRLAPLRVRYP
MSMEG_5245|M.smegmatis_MC2_155 RDAPLSVMTTWQHRHRELYEEKVAEER---NRLAQSQLDRRMTRYRKRYP
MAV_4010|M.avium_104 RGVGLCAV------------GNPS---------ARVELERRLARWMRLYP
MUL_2424|M.ulcerans_Agy99 RNVPLRAISSRVATDHGSEDGNRL---------ATAQLTRRLTRWTRLYP
MMAR_2076|M.marinum_M RQAPILALGGRPEELTDAADG---------------EFERRVQQWGQHHT
TH_2494|M.thermoresistible__bu RGVDLIALHAWSDADIADIPTLELS---AVQQSAERVLSERLAGFRERYP
* .: . : :.
Mflv_3846|M.gilvum_PYR-GCK DLDISAVRARDGLFDYLAAHGDGLQLLVAGRNRPGGVAPLVGTPGNAALR
Mvan_2549|M.vanbaalenii_PYR-1 DVEIVPVSERIDTLDYLAAHGDDVQLVVAGRNRPGGVAALVGPPGNAALR
Mb2053c|M.bovis_AF2122/97 DVRVQSAAVHGELLDYLAGLGRSVHMVVLSASDQEHVEQLVGAPGNAVLQ
Rv2028c|M.tuberculosis_H37Rv DVRVQSAAVHGELLDYLAGLGRSVHMVVLSASDQEHVEQLVGAPGNAVLQ
MAB_3904|M.abscessus_ATCC_1997 DLDIRALDPVGGTLDYLERHGHTVQLVVVGAGDAAHVQELVGPNGCGVLG
MSMEG_5245|M.smegmatis_MC2_155 ELDLELITDHGNTADYVAANPQTVQLIVVGAERFNRAGDVTDPAALGALV
MAV_4010|M.avium_104 DVQAESAVLTGGVEQHLRADHRAGRLLVTDAYR----------AEA--LC
MUL_2424|M.ulcerans_Agy99 DVRVESAIIAGHACRYMAANAKPDELYVTDSHA----------AQVCSVY
MMAR_2076|M.marinum_M DVHVYPITTQAGIARFLADHDERVQLAVIGADEADQVARLVGPSGHPIFR
TH_2494|M.thermoresistible__bu DVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTGMLLGSVSRAVV
:: .: .: * . .
Mflv_3846|M.gilvum_PYR-GCK DTDCSILVCEPPNAL
Mvan_2549|M.vanbaalenii_PYR-1 DTDCSILVCEPHNVL
Mb2053c|M.bovis_AF2122/97 EAGCTLLVVGQQYL-
Rv2028c|M.tuberculosis_H37Rv EAGCTLLVVGQQYL-
MAB_3904|M.abscessus_ATCC_1997 RTHCSVLIAERQRLL
MSMEG_5245|M.smegmatis_MC2_155 DAGCSLLTCDRQQRL
MAV_4010|M.avium_104 HAGHSVLAVRCGNL-
MUL_2424|M.ulcerans_Agy99 GAGCSVLTVRSGNL-
MMAR_2076|M.marinum_M HAECSVLVVRG----
TH_2494|M.thermoresistible__bu NAVTTPVIVAR----
: : :