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NQSHKPPSIVVGIDGSKPAVQAALWAVDEAASRDIPLRLLYAIEPDDPGYAAHGAAARKLAAAENAVRYA FTAVEAADRPVKVEVEITQERPVTSLIRASAAAALVCVGAIGVHHFRPERVGSTAAALALSAQCPVAIVR PHRVPIGRDAAWIVVEADGSSDIGVLLGAVMAEARLRDSPVRVVTCRQSGVGDTGDDVRASLDRWLARWQ PRYPDVRVQSAAVHGELLDYLAGLGRSVHMVVLSASDQEHVEQLVGAPGNAVLQEAGCTLLVVGQQYL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2028c | - | - | 100% (279) | hypothetical protein Rv2028c |
| M. tuberculosis H37Rv | Rv3134c | - | 1e-41 | 40.66% (273) | hypothetical protein Rv3134c |
| M. tuberculosis H37Rv | Rv2624c | - | 2e-41 | 36.84% (266) | hypothetical protein Rv2624c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2053c | - | 1e-157 | 100.00% (279) | hypothetical protein Mb2053c |
| M. gilvum PYR-GCK | Mflv_3846 | - | 2e-58 | 46.24% (266) | UspA domain-containing protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3904 | - | 1e-43 | 38.36% (292) | hypothetical protein MAB_3904 |
| M. marinum M | MMAR_1515 | - | 9e-42 | 41.11% (270) | hypothetical protein MMAR_1515 |
| M. avium 104 | MAV_4010 | - | 2e-34 | 39.92% (248) | hypothetical protein MAV_4010 |
| M. smegmatis MC2 155 | MSMEG_5245 | - | 2e-48 | 39.93% (278) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 3e-16 | 27.91% (301) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_2424 | - | 3e-42 | 41.11% (270) | hypothetical protein MUL_2424 |
| M. vanbaalenii PYR-1 | Mvan_2549 | - | 9e-55 | 45.08% (264) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1515|M.marinum_M -MSN-QAAPAIVVGIDGSRASTHAAVWAVDEAVSRDIPVRLVYIIDPAQA
MUL_2424|M.ulcerans_Agy99 -MSN-QAAPAIVVGIDGSRASTHAAVWAVDEAVSRDIPVRLVYIIDPAQA
MAV_4010|M.avium_104 -MSTAYPAPAIVVGVDGSRAAMHAAVWAIDEAVGRDIPLRLVYVIDPHGA
Rv2028c|M.tuberculosis_H37Rv MNQSHKP-PSIVVGIDGSKPAVQAALWAVDEAASRDIPLRLLYAIEPDDP
Mb2053c|M.bovis_AF2122/97 MNQSHKP-PSIVVGIDGSKPAVQAALWAVDEAASRDIPLRLLYAIEPDDP
Mflv_3846|M.gilvum_PYR-GCK MLDATFV-PCIVVGIDGSPAAVDAALWAVDQAVDLDIPLRLVYVIDADNE
Mvan_2549|M.vanbaalenii_PYR-1 MLEPS---ACIVVGIDGSPAGVDAALWAIEQAVDHDMPLRLVYVVDAGEH
MAB_3904|M.abscessus_ATCC_1997 MNEIRTPGPAVLVGIDGSRSAVRAALWAVDEALHRELPLRLVH-VTPQTE
MSMEG_5245|M.smegmatis_MC2_155 MSIARP----VIVGIDGSQPAVDAAIWAVKEALSRGVPLRLIYAVHPDDN
TH_2494|M.thermoresistible__bu -VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRNLQLTLVHVMTATSI
::**:*** .. *. ** .* : : *:: : .
MMAR_1515|M.marinum_M P---------------ASD-RDGRQ--SAARAALFDVQRAVEAT------
MUL_2424|M.ulcerans_Agy99 P---------------AGD-RDGRQ--SSARAALFDVQRAVEAT------
MAV_4010|M.avium_104 P---------------GGHGPDTRL--AAARAALADAHRAVDAF------
Rv2028c|M.tuberculosis_H37Rv G---------------YAAHGAAARKLAAAENAVRYAFTAVEAA------
Mb2053c|M.bovis_AF2122/97 G---------------YAAHGAAARKLAAAENAVRYAFTAVEAA------
Mflv_3846|M.gilvum_PYR-GCK D---------------AVDPHDQARQLATAEMAVRYALTALEST------
Mvan_2549|M.vanbaalenii_PYR-1 G---------------TVDPHDQARSIATAEVALRYALAAVESV------
MAB_3904|M.abscessus_ATCC_1997 ----------------FPEFSDER---SPAGTAVRHAFRQIGAT------
MSMEG_5245|M.smegmatis_MC2_155 ----------------GADHENSARALATAEVAIRQACVAVEST------
TH_2494|M.thermoresistible__bu GAPLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGPAG
: : . :
MMAR_1515|M.marinum_M GQPVKIETEILWGRPLTKLLEESRTAVMVCVGSIGLNHARRG-EGSVAGT
MUL_2424|M.ulcerans_Agy99 GQPVKIETEILWGRPLTKLLEESRTAVMVCVGSIGLNHARRG-EGSVAGT
MAV_4010|M.avium_104 AQPVKVETEILWGNTAFKLLEQSRSAVMLCVGQIGLNHACHG-GPAIATS
Rv2028c|M.tuberculosis_H37Rv DRPVKVEVEITQERPVTSLIRASAAAALVCVGAIGVHHFRPERVGSTAAA
Mb2053c|M.bovis_AF2122/97 DRPVKVEVEITQERPVTSLIRASAAAALVCVGAIGVHHFRPERVGSTAAA
Mflv_3846|M.gilvum_PYR-GCK DQPVKIEVEILRGRPVQTLLEAARSAVLLCLGARGLKHSTQGRIGSTAGA
Mvan_2549|M.vanbaalenii_PYR-1 ERPVKIEVEILQGRPVQTLLEAARSAAMLCIGARGLKHSTQGRIGSTAVA
MAB_3904|M.abscessus_ATCC_1997 HKPVKVEAEIRHGRVADVLLDASRSAVMLCVGAIGISGADTRKVGSTAAE
MSMEG_5245|M.smegmatis_MC2_155 EQPVQIELEVVQDKPIEALIAASQNTPLLCVGASGLTQAGRGGIGSVASA
TH_2494|M.thermoresistible__bu DDAVRVVTGVVRAAPVPTLVDASKQAKLVAVGSRGQGPLRRVLLGSVSSG
.*:: : *: : : ::.:* * : :
MMAR_1515|M.marinum_M LAGSALCPVAVIQSPAGAAGAPKVGEVVAEVDN----GSVLRHAFEEARL
MUL_2424|M.ulcerans_Agy99 LAGSALCPVAVIQSPAGAAGAPKVGEVVAEVDN----GSVLRHAFEEARL
MAV_4010|M.avium_104 LVRSALCPVAVVQQAPSLPAAARVSGVVAEVDN----GTVLRHAFEEARL
Rv2028c|M.tuberculosis_H37Rv LALSAQCPVAIVR-PHRVPIGRDAAWIVVEADGSSDIGVLLGAVMAEARL
Mb2053c|M.bovis_AF2122/97 LALSAQCPVAIVR-PHRVPIGRDAAWIVVEADGSSDIGVLLGAVMAEARL
Mflv_3846|M.gilvum_PYR-GCK VSTSAHCPVAVVR-AHR-PHRRPDRAVVIEITDNAGGGAVLERGLDEARR
Mvan_2549|M.vanbaalenii_PYR-1 LATSALCPVAIVR-SHR-PHRR-DRAVVIEFTD----GAVMQRGLAEAKR
MAB_3904|M.abscessus_ATCC_1997 VLRSVRCPVAVIR-DDP-SSLRGTSAVVVEIDESHESVTPLELAAHEARL
MSMEG_5245|M.smegmatis_MC2_155 VLRSAQCPVAVVA-TPG-KGRR----ILVEFDGRPSASTALQTGVDEARL
TH_2494|M.thermoresistible__bu LVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEEASF
: . ****:: :: **
MMAR_1515|M.marinum_M RNVPLRAISSRVATGHGSEDGNRL---------ATAQLTRRLTRWTRLYP
MUL_2424|M.ulcerans_Agy99 RNVPLRAISSRVATDHGSEDGNRL---------ATAQLTRRLTRWTRLYP
MAV_4010|M.avium_104 RGVGLCAV------------GNPS---------ARVELERRLARWMRLYP
Rv2028c|M.tuberculosis_H37Rv RDSPVRVVTCRQSGVGDTGDD------------VRASLDRWLARWQPRYP
Mb2053c|M.bovis_AF2122/97 RDSPVRVVTCRQSGVGDTGDD------------VRASLDRWLARWQPRYP
Mflv_3846|M.gilvum_PYR-GCK RGAPVRVLTSARS-QLDV----------------TGRWERRLAEWRRRYP
Mvan_2549|M.vanbaalenii_PYR-1 RRVPARVLIPART-HPDARSH------------ASAAWERRLAEWQRSYP
MAB_3904|M.abscessus_ATCC_1997 RAAPLRVL--LRHRPISLSGQRVATLTRVDRRVAAVHVERRLAPLRVRYP
MSMEG_5245|M.smegmatis_MC2_155 RDAPLSVMTTWQHRHRELYEEKVAEER---NRLAQSQLDRRMTRYRKRYP
TH_2494|M.thermoresistible__bu RGVDLIALHAWSDADIADIPTLELS---AVQQSAERVLSERLAGFRERYP
* .: . :: **
MMAR_1515|M.marinum_M DVRVESAIIAGHACRYMAANAKPDELYVTDSHA----------AQVCSVY
MUL_2424|M.ulcerans_Agy99 DVRVESAIIAGHACRYMAANAKPDELYVTDSHA----------AQVCSVY
MAV_4010|M.avium_104 DVQAESAVLTGGVEQHLRADHRAGRLLVTDAYR----------AEA--LC
Rv2028c|M.tuberculosis_H37Rv DVRVQSAAVHGELLDYLAGLGRSVHMVVLSASDQEHVEQLVGAPGNAVLQ
Mb2053c|M.bovis_AF2122/97 DVRVQSAAVHGELLDYLAGLGRSVHMVVLSASDQEHVEQLVGAPGNAVLQ
Mflv_3846|M.gilvum_PYR-GCK DLDISAVRARDGLFDYLAAHGDGLQLLVAGRNRPGGVAPLVGTPGNAALR
Mvan_2549|M.vanbaalenii_PYR-1 DVEIVPVSERIDTLDYLAAHGDDVQLVVAGRNRPGGVAALVGPPGNAALR
MAB_3904|M.abscessus_ATCC_1997 DLDIRALDPVGGTLDYLERHGHTVQLVVVGAGDAAHVQELVGPNGCGVLG
MSMEG_5245|M.smegmatis_MC2_155 ELDLELITDHGNTADYVAANPQTVQLIVVGAERFNRAGDVTDPAALGALV
TH_2494|M.thermoresistible__bu DVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTGMLLGSVSRAVV
:: :: .: * . :
MMAR_1515|M.marinum_M GAGCSVLTVRSGNL-
MUL_2424|M.ulcerans_Agy99 GAGCSVLTVRSGNL-
MAV_4010|M.avium_104 HAGHSVLAVRCGNL-
Rv2028c|M.tuberculosis_H37Rv EAGCTLLVVGQQYL-
Mb2053c|M.bovis_AF2122/97 EAGCTLLVVGQQYL-
Mflv_3846|M.gilvum_PYR-GCK DTDCSILVCEPPNAL
Mvan_2549|M.vanbaalenii_PYR-1 DTDCSILVCEPHNVL
MAB_3904|M.abscessus_ATCC_1997 RTHCSVLIAERQRLL
MSMEG_5245|M.smegmatis_MC2_155 DAGCSLLTCDRQQRL
TH_2494|M.thermoresistible__bu NAVTTPVIVAR----
: : :