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MFPGSVIRKLSHSEEVFAQYEVFTSMTIQLRGVIDVDALSDAFDALLETHPVLASHLEQSSDGGWNLVAD DLLHSGICVIDGTAATNGSPSGNAELRLDQSVSLLHLQLILREGGAELTLYLHHCMADGHHGAVLVDELF SRYTDAVTTGDPGPITPQPTPLSMEAVLAQRGIRKQGLSGAERFMSVMYAYEIPATETPAVLAHPGLPQA VPVTRLWLSKQQTSDLMAFGREHRLSLNAVVAAAILLTEWQLRNTPHVPIPYVYPVDLRFVLAPPVAPTE ATNLLGAASYLAEIGPNTDIVDLASDIVATLRADLANGVIQQSGLHFGTAFEGTPPGLPPLVFCTDATSF PTMRTPPGLEIEDIKGQFYCSISVPLDLYSCAVYAGQLIIEHHGHIAEPGKSLEAIRSLLCTVPSEYGWI ME
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2939 | papA5 | - | 100% (422) | acyltransferase PapA5 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2964 | papA5 | 0.0 | 100.00% (422) | acyltransferase PapA5 |
| M. gilvum PYR-GCK | Mflv_3386 | - | 1e-111 | 47.32% (410) | acyltransferase PapA5 |
| M. leprae Br4923 | MLBr_02349 | - | 0.0 | 83.80% (426) | acyltransferase PapA5 |
| M. abscessus ATCC 19977 | MAB_2035 | - | 9e-31 | 32.07% (368) | acyltransferase PapA5 |
| M. marinum M | MMAR_1768 | papA5 | 1e-132 | 54.48% (424) | polyketide synthase associated protein PapA5 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0400 | - | 7e-05 | 23.05% (243) | peptide synthetase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2011 | papA5 | 1e-132 | 54.25% (424) | acyltransferase PapA5 |
| M. vanbaalenii PYR-1 | Mvan_3119 | - | 1e-112 | 47.94% (413) | acyltransferase PapA5 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 MEPVDGALPLSRGQLDIWLSHESGLAGAEWQLGLLGKIDGVVDHGLLQQA
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 IRQALQEAEPARATFFEADGQVFQKPLDYSELEVPLYDVRDADDPEAKAR
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 EMAAEIQHTPLPLTGRLVKFALFQTRDEQFYLFGLGHHISVDGLGMALVS
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 RRISTIYTSLVTGKPVPEAYFGSLRDLVECEMSYESSADYQDDLAYWSEN
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 LPPDTGLDQGLAPTPHGKNAYTPSASVPMDPAIVGRIKELSKTLRIRRYS
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 VTTAACALLAQSWSSTGDQVALDFPVSRRVSPESKTLPAMLAGVAPLVLD
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 APPQLTVGEFCKHVDIRIRELLQHQRFPVHRLGDGGALRGPRQASNRLAV
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 NFIPSRLTLDFAGAEATASYTNHGPMGHFGLFFIGAGEELFLSTAGAGQP
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 FANFEVPELAERLGAIVAAMAADPAMPLAAVRLLAESESDRLATIGNHSA
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 LSESAPDAVSIPERFAARVAEAPDAAALTFEGRTLTYRELDEAANRFAHA
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 LLARGIGPGSRVALMSPRTDRSVIAILGAFKAGAAYVPVDPAVPAARVRF
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 ILDDASPVAVVTTAELRSRFDGHDLAVIDIDDPAIASLPATAVSDPRPDD
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 IAYVIYTSGTTGTPKGVAVTHKNLTHLIAVLEERLPKPGVWPLCHSLAFD
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 ASVWEISNALLRGGRLVVVPEAVAGSPEDFHDLLVAEQVTFLTQTPSAVA
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 MLSPDGLESMTLAVVGEACPPALVDRWATNRTMINAYGPTETTICVTSSS
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 PLEPGSVVVPIGSALPRTALFVLDPWLRPVPTGVAGELYVAGDGVTCGYI
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 GRSGLTASRFVPCPFGEPGARMYRTGDLVRWGRDGQLEYLGRADEQVKIR
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 GYRIELGEVQSALAALDGVESAAAIMREDRPGDRRLVGYITGTADPVDIR
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 AELADRLPPYMVPTAIVVLPALPLTSSNKLDTRALPAPEYANAEKNYRAP
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 SNPVEEVLADIYAQVLGVERIGVDDSFFDLGGDSILSMQVVARARAAGIQ
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 CRPRDVFVEQTVARLASVATVATEIGVVDDGTGSAAPTPIIHWLREAGGA
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 TDEFNQTLVVQAPTGVTEPDVVAVLQALLDRHATLRLRVQDSDGEWSLLV
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 PDAATVDARDCLSVVDTLSDDVVLAARAKLNPAAGAMVSALWVRQTSQLV
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 LIIHHLAVDGVSWRILLEDLNIAWAQHHSGQQVQLPAGGTSFLRWSKRLA
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 DHAHTAEVTAQADAWREILAKPAALPAVQPDTDTHASAGRFSATLDPETT
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 RQLLGEVPAAFHAGVQDILLVAFGLAWAEFLNRSGTPITVDVEGHGRHEE
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 LASDIDLSRTVGWFTTKYPVALTVADVPWAQVVAGEATLGAVVKDVKEQL
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 RAVPDGLTYGLLRYLNSEVELGGTEPTIGFNYLGRLGAGAGELSEELWRI
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 EQGSLALTDVVSAVPMPLAHTVELNAGTMDTDKGPSLQASWTWAPSVFDE
Mflv_3386|M.gilvum_PYR-GCK ------------------------------------------------MF
Mvan_3119|M.vanbaalenii_PYR-1 ------------------------------------------------MF
Rv2939|M.tuberculosis_H37Rv ------------------------------------------------MF
Mb2964|M.bovis_AF2122/97 ------------------------------------------------MF
MLBr_02349|M.leprae_Br4923 ------------------------------------------------MF
MMAR_1768|M.marinum_M ------------------------------------------------MF
MUL_2011|M.ulcerans_Agy99 ------------------------------------------------MF
MAB_2035|M.abscessus_ATCC_1997 -------------------------------------MTDTRPHQDTVDA
MSMEG_0400|M.smegmatis_MC2_155 DKAARLSQLWFEALAGICAHVQAGGGGLTPSDIAPARLTQREIDQLTTQF
Mflv_3386|M.gilvum_PYR-GCK PSSGIRKLARSEE--MFAE-TQNFV---------------GLAAHVRGTV
Mvan_3119|M.vanbaalenii_PYR-1 PSSGIRKLARSEE--MFAE-THNFI---------------GLAAHVKGSM
Rv2939|M.tuberculosis_H37Rv PGSVIRKLSHSEE--VFAQ-YEVFT---------------SMTIQLRGVI
Mb2964|M.bovis_AF2122/97 PGSVIRKLSHSEE--VFAQ-YEVFT---------------SMTIQLRGVI
MLBr_02349|M.leprae_Br4923 AGSVIRKLSHSEE--VFAR-YEVFT---------------SMTIQLRGVL
MMAR_1768|M.marinum_M PGAVIRKLAFSEE--IYAR-YQAFT---------------SFTAHVRGPV
MUL_2011|M.ulcerans_Agy99 PGAVIRKLAFSEE--IYAR-YQAFT---------------SFTAHVRGPV
MAB_2035|M.abscessus_ATCC_1997 PGEPIRPLSRLET--YFTFGFGHFG---------------GQSMLISGDL
MSMEG_0400|M.smegmatis_MC2_155 EVADVLPLTPLQQGLLFQAGFAEAAGAEAAGVPSDDVYAVQLGITLSGSL
: *: : : : * :
Mflv_3386|M.gilvum_PYR-GCK DETALADAFDALLQAHPVLNG-HLEQLPDGKWEIVLDDLMHEGLEVVEC-
Mvan_3119|M.vanbaalenii_PYR-1 DADALSDAFDLLLQAHPVLGG-HLEQLPDGKWEIVLDDLMHPGIEVVEL-
Rv2939|M.tuberculosis_H37Rv DVDALSDAFDALLETHPVLAS-HLEQSSDGGWNLVADDLLHSGICVIDG-
Mb2964|M.bovis_AF2122/97 DVDALSDAFDALLETHPVLAS-HLEQSSDGGWNLVADDLLHSGICVIDG-
MLBr_02349|M.leprae_Br4923 DIDALSEAFDALVQAHPVLAS-HLETSSDGGWNLVADDLLHPGICVVDAN
MMAR_1768|M.marinum_M DIDAMSEAFDALLQAHPVFAA-HLEEGPDGNHHIVANDLLHSGLVVIDG-
MUL_2011|M.ulcerans_Agy99 DIDAMSEAFDALLQAHPVFAA-HLEEGPDGNHHIVANDLLHSGLVVIDG-
MAB_2035|M.abscessus_ATCC_1997 DIEALNDTCIEMQLRHESLRS-IIRK-NDQVPEFVATHRPPKSIRVFEG-
MSMEG_0400|M.smegmatis_MC2_155 DPQQLRDAVQAVIRRHPNLAARFVEQFGEPVQVLSVDPEIGWQFVEFDSG
* : :: : * : . :. : : : .:
Mflv_3386|M.gilvum_PYR-GCK -----------HGDQEPPPLLFDQTAALTHLRLTRRDDETHLTLYIHHSL
Mvan_3119|M.vanbaalenii_PYR-1 -----------TGDEPAPPLIFDQTVSLVHLRLTIRDGQAQPTLYIHHSL
Rv2939|M.tuberculosis_H37Rv ------TAATNGSPSGNAELRLDQSVSLLHLQLILREGGAELTLYLHHCM
Mb2964|M.bovis_AF2122/97 ------TAATNGSPSGNAELRLDQSVSLLHLQLILREGGAELTLYLHHCM
MLBr_02349|M.leprae_Br4923 ------NGAQSGCGGIQSETRLDQSVSLLNLRLTPREGGGELVLYIHHSM
MMAR_1768|M.marinum_M ------------RRAENPHVQLDQRDSLFRLQLTLGESENLVTAYVHHSL
MUL_2011|M.ulcerans_Agy99 ------------RRAENPHVQLDQRDSLFRLQLTLGESENLVTAYVHHSL
MAB_2035|M.abscessus_ATCC_1997 --------EDLGARSTGREAVFDQTQQLFYVDLLLGDGQARVTFFVHHSI
MSMEG_0400|M.smegmatis_MC2_155 DTGVDERVERLCAAERSAVCKLGEQPVFRAALIRTADNLHRFVLTIHHIV
:.: : : :. . :** :
Mflv_3386|M.gilvum_PYR-GCK ADGHHQFSLVEELFSTYTDLVT----------------------------
Mvan_3119|M.vanbaalenii_PYR-1 ADGHHQFSLVEELFSTYTDLVT----------------------------
Rv2939|M.tuberculosis_H37Rv ADGHHGAVLVDELFSRYTDAVT----------------------------
Mb2964|M.bovis_AF2122/97 ADGHHGAVLVDELFSRYTDAVT----------------------------
MLBr_02349|M.leprae_Br4923 ADGHHGAVLVDELFSRYTDVVT----------------------------
MMAR_1768|M.marinum_M ADAHHLGSLLDELLSRYTDVVT----------------------------
MUL_2011|M.ulcerans_Agy99 ADAHHLGSLLDELLSRYTDVVT----------------------------
MAB_2035|M.abscessus_ATCC_1997 ADGRHGSAILIEFWSLYVQRVE----------------------------
MSMEG_0400|M.smegmatis_MC2_155 IDGWSLPVLLQEIFAAYFDQSLPSAAPYRNFVTWLGAQDRDAAQAAWGSV
*. :: *: : * :
Mflv_3386|M.gilvum_PYR-GCK -TGTARQAPVAPAPAA----------------------------LETILS
Mvan_3119|M.vanbaalenii_PYR-1 -TGTTKPVEVHPAPEP----------------------------LEVILA
Rv2939|M.tuberculosis_H37Rv -TGDPGPITPQPTPLS----------------------------MEAVLA
Mb2964|M.bovis_AF2122/97 -TGDPGPITPQPTPLS----------------------------MEAVLA
MLBr_02349|M.leprae_Br4923 -TGDPGPIIPQATPLS----------------------------MEAVLQ
MMAR_1768|M.marinum_M -TGDPGPITPEPAPQP----------------------------AEDLLK
MUL_2011|M.ulcerans_Agy99 -TGDPGPITPEPAPQP----------------------------AEDLLK
MAB_2035|M.abscessus_ATCC_1997 -EGQFPPILTQKFPQS----------------------------GEYFLN
MSMEG_0400|M.smegmatis_MC2_155 LEGFETPTLVAPPAQAGPRGVESFRLSEATTRTLGELARSQHTTVNTVLQ
* . . : .*
Mflv_3386|M.gilvum_PYR-GCK DRGVEKKLRSGLERLLAAMFAYDVPPSRRAPAENNPVLP-QRVPMEFCKL
Mvan_3119|M.vanbaalenii_PYR-1 NRGVEKRTRSGLERLLAAMFVYDLPPSRRAPSDVNPVLP-QLVPMAYCTL
Rv2939|M.tuberculosis_H37Rv QRGIRKQGLSGAERFMSVMYAYEIPATETPAVLAHPGLP-QAVPVTRLWL
Mb2964|M.bovis_AF2122/97 QRGIRKQGLSGAERFMSVMYAYEIPATETPAVLAHPGLP-QAVPVTRLWL
MLBr_02349|M.leprae_Br4923 QRGVKKHALSGAERFMSVMYAYDLPATGTPAVLAEPGLP-QAVPVTRLWL
MMAR_1768|M.marinum_M RRGIKQSALTGFERFLPLLFAYDLPP--IAEEMRKFEAP-EPVPVTRCRL
MUL_2011|M.ulcerans_Agy99 RRGIKQSALTGFERFLPLLFAYDLPP--IAEEMRKFEAP-EPVPVTRCRL
MAB_2035|M.abscessus_ATCC_1997 -----RTQYPGADPSVKADEVLRVPLWDEAALAQKLPPPREPALAKQMTL
MSMEG_0400|M.smegmatis_MC2_155 AAWAQLLMWMTGQRDVVFGTAVSGRPVDLAGADSMVGLLINTVPVRATSG
: : . . : .
Mflv_3386|M.gilvum_PYR-GCK SEAETENIIGFCRANK-----------------LGLNSLLSASILMAEWQ
Mvan_3119|M.vanbaalenii_PYR-1 SEQDTEKIIAFCRANK-----------------LGLNSLLSAAVLMAEWN
Rv2939|M.tuberculosis_H37Rv SKQQTSDLMAFGREHR-----------------LSLNAVVAAAILLTEWQ
Mb2964|M.bovis_AF2122/97 SKQQTSDLMAFGREHR-----------------LSLNAVVAAAILLTEWQ
MLBr_02349|M.leprae_Br4923 TKQETSDLAAFGREHR-----------------LSINAVVAAAILMTEWR
MMAR_1768|M.marinum_M TSQETADLVSFSRDNG-----------------LSFNAVLAAAILLAEWR
MUL_2011|M.ulcerans_Agy99 TSQETADLVSFSRDNG-----------------LSFNAVLAAAILLAEWR
MAB_2035|M.abscessus_ATCC_1997 EKLGRASLARLGNIES-----------------ISINALVSAALIRAHVR
MSMEG_0400|M.smegmatis_MC2_155 VATTVTDLLGQLQRDHNDTVDHEHMALNEIHRLTGHDRLFDTLFVYENYP
.: . . . : :. : .: .
Mflv_3386|M.gilvum_PYR-GCK LRETPNIPVPYVYPVDLR----YLLSPPVSATECTNPVGIATYLAEISPD
Mvan_3119|M.vanbaalenii_PYR-1 VRRTPNIPVPYVYPVDLR----YLLSPPVSATESTNPVGIATYLAEIEKG
Rv2939|M.tuberculosis_H37Rv LRNTPHVPIPYVYPVDLR----FVLAPPVAPTEATNLLGAASYLAEIGPN
Mb2964|M.bovis_AF2122/97 LRNTPHVPIPYVYPVDLR----FVLAPPVAPTEATNLLGAASYLAEIGPN
MLBr_02349|M.leprae_Br4923 LRETPHVPIPYVYPVDLR----YVLAPPVAPTESTNLLGAAGYLAEIGQD
MMAR_1768|M.marinum_M LRETPHVPIPYCYAVDLR----FLLSPPVGATESTNPVGLATYLAEIGPD
MUL_2011|M.ulcerans_Agy99 LRETPHVPIPYCYAVDLR----FLLSPPVGATESTNPVGLATYLAEIGPD
MAB_2035|M.abscessus_ATCC_1997 AGDP--VPL-YFYPVDLR----DCVTPPVAPTEATNLLSNA-WFGDVEIG
MSMEG_0400|M.smegmatis_MC2_155 IDANALLSVQDLAVTDFASREYNHYPLSMVATPGHEVVLRVEFDTEIFDA
:.: .*: . .: .* : : . : ::
Mflv_3386|M.gilvum_PYR-GCK TDVVDLARDINDTFKADIADGVIQQSFLHFS-------------------
Mvan_3119|M.vanbaalenii_PYR-1 TDIAELARDINDTYKKDIAEGVIQQSFLHFS-------------------
Rv2939|M.tuberculosis_H37Rv TDIVDLASDIVATLRADLANGVIQQSGLHFG-------------------
Mb2964|M.bovis_AF2122/97 TDIVDLASDIVATLRADLANGVIQQSGLHFG-------------------
MLBr_02349|M.leprae_Br4923 TDIVDLATDIVATLRADLANGVVQQSGLHFG-------------------
MMAR_1768|M.marinum_M TDITELAADIVATFRADLSDGMIHQSALRSG-------------------
MUL_2011|M.ulcerans_Agy99 TDITELAADIVATFRADLSDGMIHQSALRSG-------------------
MAB_2035|M.abscessus_ATCC_1997 PDLVTLARKIHVQFDRDLADGTIHRTRVRNE-------------------
MSMEG_0400|M.smegmatis_MC2_155 ASIEALVDRLRRVLDAMATDPGRRLSTIDLLDPQEHDRLDEWGNRAVLTR
..: *. : :: : : :
Mflv_3386|M.gilvum_PYR-GCK --PQYVGNPPGLPD------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --PQYVGNPPGLPD------------------------------------
Rv2939|M.tuberculosis_H37Rv --TAFEGTPPGLPP------------------------------------
Mb2964|M.bovis_AF2122/97 --TAFEGTPPGLPP------------------------------------
MLBr_02349|M.leprae_Br4923 --TAFEGTPPGLPP------------------------------------
MMAR_1768|M.marinum_M --RILEGTPPGLPP------------------------------------
MUL_2011|M.ulcerans_Agy99 --RILEGTPPGLPP------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --PTKLLADKSFGG------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 PAPALESIPASFAESVRRVPDAVALSCGDRSWTYRELDEASNRMAHLLAG
.:
Mflv_3386|M.gilvum_PYR-GCK ------------------------VVMFTDNGIVPPMRMPPDMELAASHG
Mvan_3119|M.vanbaalenii_PYR-1 ------------------------VVMFTDNGIVPPLRTPPDMEVAASHG
Rv2939|M.tuberculosis_H37Rv ------------------------LVFCTDATSFPTMRTPPGLEIEDIKG
Mb2964|M.bovis_AF2122/97 ------------------------LVFCTDATSFPTMRTPPGLEIEDIKG
MLBr_02349|M.leprae_Br4923 ------------------------LVFCTDATAFPTMRTPPDLAIEDIQG
MMAR_1768|M.marinum_M ------------------------FVLCTNVSTLPPIRTPEDVELVDFHS
MUL_2011|M.ulcerans_Agy99 ------------------------FILCTNVSTLPPIRTPEDVELVDFHS
MAB_2035|M.abscessus_ATCC_1997 ------------------------AIHATQLGRIRVPRLPGNLVVDDITS
MSMEG_0400|M.smegmatis_MC2_155 RGAKPGERVAMLLPRTGEAVVTILAILKTGAAYLPIDPAHPDARIEFVLK
: * . . :
Mflv_3386|M.gilvum_PYR-GCK ELYFAVGAGIEIYTSKIFAG----------------------------RL
Mvan_3119|M.vanbaalenii_PYR-1 EFYFAVGAGIEIYTSKIFNG----------------------------QL
Rv2939|M.tuberculosis_H37Rv QFYCSISVPLDLYSCAVYAG----------------------------QL
Mb2964|M.bovis_AF2122/97 QFYCSISVPLDLYSCAVYAG----------------------------QL
MLBr_02349|M.leprae_Br4923 RFYCSISVPLDLYSCGVYEG----------------------------QL
MMAR_1768|M.marinum_M RIHCAMDVPFGFYACSIATD----------------------------RL
MUL_2011|M.ulcerans_Agy99 RIHCAMDVPFGFYACSIATD----------------------------RL
MAB_2035|M.abscessus_ATCC_1997 SHASALGPAIYTFLYGREVS----------------------------VY
MSMEG_0400|M.smegmatis_MC2_155 DAAPVAAVSSADLCTRLIASGVPVIEVDDPAIGAEASTSLPVPAVDDIAY
.
Mflv_3386|M.gilvum_PYR-GCK MIEYHSHGPAP---EKSVQTIETLLRGIAARQAAARVS------------
Mvan_3119|M.vanbaalenii_PYR-1 MIEYHSHGPDR---EKSVAAIEEQLRAVVARQSGVG--------------
Rv2939|M.tuberculosis_H37Rv IIEHHGHIAEP---GKSLEAIRSLLCTVPSEYGWIME-------------
Mb2964|M.bovis_AF2122/97 IIEHHGHIAEP---GKSLEAIRSLLCTVPSEYGWIME-------------
MLBr_02349|M.leprae_Br4923 IIEHHGHIEEP---AKALEAIRSLLCTVPSEYGWIME-------------
MMAR_1768|M.marinum_M SIELHGSIPAP---QLLLDAIRDILCSVPSEYGLFME-------------
MUL_2011|M.ulcerans_Agy99 SIELHGSIPAP---QLLLDAIRDILCSVPSEYGLFME-------------
MAB_2035|M.abscessus_ATCC_1997 TIDSLNQRLRVGFLAGSYEKSDELLAYIEDELTAAIDARI----------
MSMEG_0400|M.smegmatis_MC2_155 IIYTSGTTGTPKGVAVTHRNVAQLLDTLGAQLELGQTWTQCHSLAFDYSV
* . * : .
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 WEIWGPLLNGGRLLMVPDAVVRSPEDLHAMLVAEQVSMLSQTPSAFYALQ
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 TADALYPERGEQLKLQTVVFGGEALEPHRLSGWMHAHPGMPRMINMYGIT
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 ETTVHASFREIGEADLANSTSPIGVPLEHLSFFVLDGWLRQVPVGVVGEL
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 YVAGEGLACGYISRSDLTSTRFVACPFGAPGARMYRTGDLVRWGADGQLQ
Mflv_3386|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3119|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2939|M.tuberculosis_H37Rv --------------------------------------------------
Mb2964|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02349|M.leprae_Br4923 --------------------------------------------------
MMAR_1768|M.marinum_M --------------------------------------------------
MUL_2011|M.ulcerans_Agy99 --------------------------------------------------
MAB_2035|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0400|M.smegmatis_MC2_155 YVGRADEQVKIRGYRIELGEVHAALVGLDGVEQAAVIAREDRPATSGWSV
Mflv_3386|M.gilvum_PYR-GCK -----------------------------
Mvan_3119|M.vanbaalenii_PYR-1 -----------------------------
Rv2939|M.tuberculosis_H37Rv -----------------------------
Mb2964|M.bovis_AF2122/97 -----------------------------
MLBr_02349|M.leprae_Br4923 -----------------------------
MMAR_1768|M.marinum_M -----------------------------
MUL_2011|M.ulcerans_Agy99 -----------------------------
MAB_2035|M.abscessus_ATCC_1997 -----------------------------
MSMEG_0400|M.smegmatis_MC2_155 MSPARSTRSRPGPRSPSGSPRTWCPRRSW