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FPSSGIRKLARSEEMFAETHNFIGLAAHVKGSMDADALSDAFDLLLQAHPVLGGHLEQLPDGKWEIVLDD LMHPGIEVVELTGDEPAPPLIFDQTVSLVHLRLTIRDGQAQPTLYIHHSLADGHHQFSLVEELFSTYTDL VTTGTTKPVEVHPAPEPLEVILANRGVEKRTRSGLERLLAAMFVYDLPPSRRAPSDVNPVLPQLVPMAYC TLSEQDTEKIIAFCRANKLGLNSLLSAAVLMAEWNVRRTPNIPVPYVYPVDLRYLLSPPVSATESTNPVG IATYLAEIEKGTDIAELARDINDTYKKDIAEGVIQQSFLHFSPQYVGNPPGLPDVVMFTDNGIVPPLRTP PDMEVAASHGEFYFAVGAGIEIYTSKIFNGQLMIEYHSHGPDREKSVAAIEEQLRAVVARQSGVG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3119 | - | - | 100% (416) | acyltransferase PapA5 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2964 | papA5 | 1e-112 | 47.94% (413) | acyltransferase PapA5 |
| M. gilvum PYR-GCK | Mflv_3386 | - | 0.0 | 79.66% (413) | acyltransferase PapA5 |
| M. tuberculosis H37Rv | Rv2939 | papA5 | 1e-112 | 47.94% (413) | acyltransferase PapA5 |
| M. leprae Br4923 | MLBr_02349 | - | 1e-109 | 47.10% (414) | acyltransferase PapA5 |
| M. abscessus ATCC 19977 | MAB_2035 | - | 1e-30 | 26.40% (428) | acyltransferase PapA5 |
| M. marinum M | MMAR_1768 | papA5 | 1e-100 | 46.08% (408) | polyketide synthase associated protein PapA5 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2011 | papA5 | 1e-100 | 45.83% (408) | acyltransferase PapA5 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3119|M.vanbaalenii_PYR-1 -----------MFPSSGIRKLARSEEMFAE-THNFIGLAAHVKGSMDADA
Mflv_3386|M.gilvum_PYR-GCK -----------MFPSSGIRKLARSEEMFAE-TQNFVGLAAHVRGTVDETA
MMAR_1768|M.marinum_M -----------MFPGAVIRKLAFSEEIYAR-YQAFTSFTAHVRGPVDIDA
MUL_2011|M.ulcerans_Agy99 -----------MFPGAVIRKLAFSEEIYAR-YQAFTSFTAHVRGPVDIDA
Mb2964|M.bovis_AF2122/97 -----------MFPGSVIRKLSHSEEVFAQ-YEVFTSMTIQLRGVIDVDA
Rv2939|M.tuberculosis_H37Rv -----------MFPGSVIRKLSHSEEVFAQ-YEVFTSMTIQLRGVIDVDA
MLBr_02349|M.leprae_Br4923 -----------MFAGSVIRKLSHSEEVFAR-YEVFTSMTIQLRGVLDIDA
MAB_2035|M.abscessus_ATCC_1997 MTDTRPHQDTVDAPGEPIRPLSRLETYFTFGFGHFGGQSMLISGDLDIEA
.. ** *: * :: * . : : * :* *
Mvan_3119|M.vanbaalenii_PYR-1 LSDAFDLLLQAHPVLGGHLEQLPDGKWEIVLDDLMHPGIEVVEL------
Mflv_3386|M.gilvum_PYR-GCK LADAFDALLQAHPVLNGHLEQLPDGKWEIVLDDLMHEGLEVVEC------
MMAR_1768|M.marinum_M MSEAFDALLQAHPVFAAHLEEGPDGNHHIVANDLLHSGLVVIDG------
MUL_2011|M.ulcerans_Agy99 MSEAFDALLQAHPVFAAHLEEGPDGNHHIVANDLLHSGLVVIDG------
Mb2964|M.bovis_AF2122/97 LSDAFDALLETHPVLASHLEQSSDGGWNLVADDLLHSGICVIDG-TAATN
Rv2939|M.tuberculosis_H37Rv LSDAFDALLETHPVLASHLEQSSDGGWNLVADDLLHSGICVIDG-TAATN
MLBr_02349|M.leprae_Br4923 LSEAFDALVQAHPVLASHLETSSDGGWNLVADDLLHPGICVVDANNGAQS
MAB_2035|M.abscessus_ATCC_1997 LNDTCIEMQLRHESLRSIIRK-NDQVPEFVATHRPPKSIRVFEG---EDL
: :: : * : . :. * .:* . .: *.:
Mvan_3119|M.vanbaalenii_PYR-1 TGDEPAPPLIFDQTVSLVHLRLTIRDGQAQPTLYIHHSLADGHHQFSLVE
Mflv_3386|M.gilvum_PYR-GCK HGDQEPPPLLFDQTAALTHLRLTRRDDETHLTLYIHHSLADGHHQFSLVE
MMAR_1768|M.marinum_M -RRAENPHVQLDQRDSLFRLQLTLGESENLVTAYVHHSLADAHHLGSLLD
MUL_2011|M.ulcerans_Agy99 -RRAENPHVQLDQRDSLFRLQLTLGESENLVTAYVHHSLADAHHLGSLLD
Mb2964|M.bovis_AF2122/97 GSPSGNAELRLDQSVSLLHLQLILREGGAELTLYLHHCMADGHHGAVLVD
Rv2939|M.tuberculosis_H37Rv GSPSGNAELRLDQSVSLLHLQLILREGGAELTLYLHHCMADGHHGAVLVD
MLBr_02349|M.leprae_Br4923 GCGGIQSETRLDQSVSLLNLRLTPREGGGELVLYIHHSMADGHHGAVLVD
MAB_2035|M.abscessus_ATCC_1997 GARSTGREAVFDQTQQLFYVDLLLGDGQARVTFFVHHSIADGRHGSAILI
:** * : * :. . ::**.:**.:* ::
Mvan_3119|M.vanbaalenii_PYR-1 ELFSTYTDLVTTGTTKPVEVHPAPEPLEVILANRGVEKRTRSGLERLLAA
Mflv_3386|M.gilvum_PYR-GCK ELFSTYTDLVTTGTARQAPVAPAPAALETILSDRGVEKKLRSGLERLLAA
MMAR_1768|M.marinum_M ELLSRYTDVVTTGDPGPITPEPAPQPAEDLLKRRGIKQSALTGFERFLPL
MUL_2011|M.ulcerans_Agy99 ELLSRYTDVVTTGDPGPITPEPAPQPAEDLLKRRGIKQSALTGFERFLPL
Mb2964|M.bovis_AF2122/97 ELFSRYTDAVTTGDPGPITPQPTPLSMEAVLAQRGIRKQGLSGAERFMSV
Rv2939|M.tuberculosis_H37Rv ELFSRYTDAVTTGDPGPITPQPTPLSMEAVLAQRGIRKQGLSGAERFMSV
MLBr_02349|M.leprae_Br4923 ELFSRYTDVVTTGDPGPIIPQATPLSMEAVLQQRGVKKHALSGAERFMSV
MAB_2035|M.abscessus_ATCC_1997 EFWSLYVQRVEEGQFPPILTQKFPQSGEYFLN-----RTQYPGADPSVKA
*: * *.: * * * . * .* : .* : :
Mvan_3119|M.vanbaalenii_PYR-1 MFVYDLPPSRRAPSDVNPVLP-QLVPMAYCTLSEQDTEKIIAFCRANKLG
Mflv_3386|M.gilvum_PYR-GCK MFAYDVPPSRRAPAENNPVLP-QRVPMEFCKLSEAETENIIGFCRANKLG
MMAR_1768|M.marinum_M LFAYDLPP--IAEEMRKFEAP-EPVPVTRCRLTSQETADLVSFSRDNGLS
MUL_2011|M.ulcerans_Agy99 LFAYDLPP--IAEEMRKFEAP-EPVPVTRCRLTSQETADLVSFSRDNGLS
Mb2964|M.bovis_AF2122/97 MYAYEIPATETPAVLAHPGLP-QAVPVTRLWLSKQQTSDLMAFGREHRLS
Rv2939|M.tuberculosis_H37Rv MYAYEIPATETPAVLAHPGLP-QAVPVTRLWLSKQQTSDLMAFGREHRLS
MLBr_02349|M.leprae_Br4923 MYAYDLPATGTPAVLAEPGLP-QAVPVTRLWLTKQETSDLAAFGREHRLS
MAB_2035|M.abscessus_ATCC_1997 DEVLRVPLWDEAALAQKLPPPREPALAKQMTLEKLGRASLARLGNIESIS
. :* . . * : . * . .: : . . :.
Mvan_3119|M.vanbaalenii_PYR-1 LNSLLSAAVLMAEWNVRRTPNIPVPYVYPVDLRYLLSPPVSATESTNPVG
Mflv_3386|M.gilvum_PYR-GCK LNSLLSASILMAEWQLRETPNIPVPYVYPVDLRYLLSPPVSATECTNPVG
MMAR_1768|M.marinum_M FNAVLAAAILLAEWRLRETPHVPIPYCYAVDLRFLLSPPVGATESTNPVG
MUL_2011|M.ulcerans_Agy99 FNAVLAAAILLAEWRLRETPHVPIPYCYAVDLRFLLSPPVGATESTNPVG
Mb2964|M.bovis_AF2122/97 LNAVVAAAILLTEWQLRNTPHVPIPYVYPVDLRFVLAPPVAPTEATNLLG
Rv2939|M.tuberculosis_H37Rv LNAVVAAAILLTEWQLRNTPHVPIPYVYPVDLRFVLAPPVAPTEATNLLG
MLBr_02349|M.leprae_Br4923 INAVVAAAILMTEWRLRETPHVPIPYVYPVDLRYVLAPPVAPTESTNLLG
MAB_2035|M.abscessus_ATCC_1997 INALVSAALIRAHVRAGDP--VPL-YFYPVDLRDCVTPPVAPTEATNLLS
:*::::*::: :. . . :*: * *.**** ::***..**.** :.
Mvan_3119|M.vanbaalenii_PYR-1 IATYLAEIEKGTDIAELARDINDTYKKDIAEGVIQQSFLHFSPQYVGNPP
Mflv_3386|M.gilvum_PYR-GCK IATYLAEISPDTDVVDLARDINDTFKADIADGVIQQSFLHFSPQYVGNPP
MMAR_1768|M.marinum_M LATYLAEIGPDTDITELAADIVATFRADLSDGMIHQSALRSGRILEGTPP
MUL_2011|M.ulcerans_Agy99 LATYLAEIGPDTDITELAADIVATFRADLSDGMIHQSALRSGRILEGTPP
Mb2964|M.bovis_AF2122/97 AASYLAEIGPNTDIVDLASDIVATLRADLANGVIQQSGLHFGTAFEGTPP
Rv2939|M.tuberculosis_H37Rv AASYLAEIGPNTDIVDLASDIVATLRADLANGVIQQSGLHFGTAFEGTPP
MLBr_02349|M.leprae_Br4923 AAGYLAEIGQDTDIVDLATDIVATLRADLANGVVQQSGLHFGTAFEGTPP
MAB_2035|M.abscessus_ATCC_1997 NA-WFGDVEIGPDLVTLARKIHVQFDRDLADGTIHRTRVRNEPTKLLADK
* ::.:: ..*:. ** .* *:::* :::: ::
Mvan_3119|M.vanbaalenii_PYR-1 GLPDVVMFTDNGIVPPLRTPPDMEVAASHGEFYFAVGAGIEIYTSKIFNG
Mflv_3386|M.gilvum_PYR-GCK GLPDVVMFTDNGIVPPMRMPPDMELAASHGELYFAVGAGIEIYTSKIFAG
MMAR_1768|M.marinum_M GLPPFVLCTNVSTLPPIRTPEDVELVDFHSRIHCAMDVPFGFYACSIATD
MUL_2011|M.ulcerans_Agy99 GLPPFILCTNVSTLPPIRTPEDVELVDFHSRIHCAMDVPFGFYACSIATD
Mb2964|M.bovis_AF2122/97 GLPPLVFCTDATSFPTMRTPPGLEIEDIKGQFYCSISVPLDLYSCAVYAG
Rv2939|M.tuberculosis_H37Rv GLPPLVFCTDATSFPTMRTPPGLEIEDIKGQFYCSISVPLDLYSCAVYAG
MLBr_02349|M.leprae_Br4923 GLPPLVFCTDATAFPTMRTPPDLAIEDIQGRFYCSISVPLDLYSCGVYEG
MAB_2035|M.abscessus_ATCC_1997 SFGGAIHATQLGRIRVPRLPGNLVVDDITSSHASALGPAIYTFLYGREVS
.: : *: . * * .: : . ::. : : .
Mvan_3119|M.vanbaalenii_PYR-1 QLMIEYHSHGPDR---EKSVAAIEEQLRAVVARQSGVG----
Mflv_3386|M.gilvum_PYR-GCK RLMIEYHSHGPAP---EKSVQTIETLLRGIAARQAAARVS--
MMAR_1768|M.marinum_M RLSIELHGSIPAP---QLLLDAIRDILCSVPSEYGLFME---
MUL_2011|M.ulcerans_Agy99 RLSIELHGSIPAP---QLLLDAIRDILCSVPSEYGLFME---
Mb2964|M.bovis_AF2122/97 QLIIEHHGHIAEP---GKSLEAIRSLLCTVPSEYGWIME---
Rv2939|M.tuberculosis_H37Rv QLIIEHHGHIAEP---GKSLEAIRSLLCTVPSEYGWIME---
MLBr_02349|M.leprae_Br4923 QLIIEHHGHIEEP---AKALEAIRSLLCTVPSEYGWIME---
MAB_2035|M.abscessus_ATCC_1997 VYTIDSLNQRLRVGFLAGSYEKSDELLAYIEDELTAAIDARI
*: . * : .