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M. abscessus ATCC 19977 MAB_2035 (-)

annotation: acyltransferase PapA5
coordinates: 2034647 - 2035936
length: 429

VTDTRPHQDTVDAPGEPIRPLSRLETYFTFGFGHFGGQSMLISGDLDIEALNDTCIEMQLRHESLRSIIR
KNDQVPEFVATHRPPKSIRVFEGEDLGARSTGREAVFDQTQQLFYVDLLLGDGQARVTFFVHHSIADGRH
GSAILIEFWSLYVQRVEEGQFPPILTQKFPQSGEYFLNRTQYPGADPSVKADEVLRVPLWDEAALAQKLP
PPREPALAKQMTLEKLGRASLARLGNIESISINALVSAALIRAHVRAGDPVPLYFYPVDLRDCVTPPVAP
TEATNLLSNAWFGDVEIGPDLVTLARKIHVQFDRDLADGTIHRTRVRNEPTKLLADKSFGGAIHATQLGR
IRVPRLPGNLVVDDITSSHASALGPAIYTFLYGREVSVYTIDSLNQRLRVGFLAGSYEKSDELLAYIEDE
LTAAIDARI
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2035--100% (429)acyltransferase PapA5
M. abscessus ATCC 19977MAB_4931-1e-0624.70% (332) acyltransferase PapA5

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2964papA58e-3131.15% (366) acyltransferase PapA5
M. gilvum PYR-GCKMflv_3386-2e-2325.19% (405) acyltransferase PapA5
M. tuberculosis H37RvRv2939papA58e-3131.15% (366) acyltransferase PapA5
M. leprae Br4923MLBr_02349-2e-2729.23% (366) acyltransferase PapA5
M. marinum MMMAR_1768papA53e-2429.66% (327) polyketide synthase associated protein PapA5
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_2011papA52e-2429.66% (327) acyltransferase PapA5
M. vanbaalenii PYR-1Mvan_3119-2e-3026.40% (428) acyltransferase PapA5

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1768|M.marinum_M               -----------MFPGAVIRKLAFSEEIYAR-YQAFTSFTAHVRGPVDIDA
MUL_2011|M.ulcerans_Agy99           -----------MFPGAVIRKLAFSEEIYAR-YQAFTSFTAHVRGPVDIDA
Mb2964|M.bovis_AF2122/97            -----------MFPGSVIRKLSHSEEVFAQ-YEVFTSMTIQLRGVIDVDA
Rv2939|M.tuberculosis_H37Rv         -----------MFPGSVIRKLSHSEEVFAQ-YEVFTSMTIQLRGVIDVDA
MLBr_02349|M.leprae_Br4923          -----------MFAGSVIRKLSHSEEVFAR-YEVFTSMTIQLRGVLDIDA
Mflv_3386|M.gilvum_PYR-GCK          -----------MFPSSGIRKLARSEEMFAE-TQNFVGLAAHVRGTVDETA
Mvan_3119|M.vanbaalenii_PYR-1       -----------MFPSSGIRKLARSEEMFAE-THNFIGLAAHVKGSMDADA
MAB_2035|M.abscessus_ATCC_1997      MTDTRPHQDTVDAPGEPIRPLSRLETYFTFGFGHFGGQSMLISGDLDIEA
                                                 ..  ** *:  *  ::     * . :  : * :*  *

MMAR_1768|M.marinum_M               MSEAFDALLQAHPVFAAHLEEGPDGNHHIVANDLLHSGLVVIDG------
MUL_2011|M.ulcerans_Agy99           MSEAFDALLQAHPVFAAHLEEGPDGNHHIVANDLLHSGLVVIDG------
Mb2964|M.bovis_AF2122/97            LSDAFDALLETHPVLASHLEQSSDGGWNLVADDLLHSGICVIDG-TAATN
Rv2939|M.tuberculosis_H37Rv         LSDAFDALLETHPVLASHLEQSSDGGWNLVADDLLHSGICVIDG-TAATN
MLBr_02349|M.leprae_Br4923          LSEAFDALVQAHPVLASHLETSSDGGWNLVADDLLHPGICVVDANNGAQS
Mflv_3386|M.gilvum_PYR-GCK          LADAFDALLQAHPVLNGHLEQLPDGKWEIVLDDLMHEGLEVVEC------
Mvan_3119|M.vanbaalenii_PYR-1       LSDAFDLLLQAHPVLGGHLEQLPDGKWEIVLDDLMHPGIEVVEL------
MAB_2035|M.abscessus_ATCC_1997      LNDTCIEMQLRHESLRSIIRK-NDQVPEFVATHRPPKSIRVFEG---EDL
                                    : ::   :   *  : . :.   *   .:*  .    .: *.:       

MMAR_1768|M.marinum_M               -RRAENPHVQLDQRDSLFRLQLTLGESENLVTAYVHHSLADAHHLGSLLD
MUL_2011|M.ulcerans_Agy99           -RRAENPHVQLDQRDSLFRLQLTLGESENLVTAYVHHSLADAHHLGSLLD
Mb2964|M.bovis_AF2122/97            GSPSGNAELRLDQSVSLLHLQLILREGGAELTLYLHHCMADGHHGAVLVD
Rv2939|M.tuberculosis_H37Rv         GSPSGNAELRLDQSVSLLHLQLILREGGAELTLYLHHCMADGHHGAVLVD
MLBr_02349|M.leprae_Br4923          GCGGIQSETRLDQSVSLLNLRLTPREGGGELVLYIHHSMADGHHGAVLVD
Mflv_3386|M.gilvum_PYR-GCK          HGDQEPPPLLFDQTAALTHLRLTRRDDETHLTLYIHHSLADGHHQFSLVE
Mvan_3119|M.vanbaalenii_PYR-1       TGDEPAPPLIFDQTVSLVHLRLTIRDGQAQPTLYIHHSLADGHHQFSLVE
MAB_2035|M.abscessus_ATCC_1997      GARSTGREAVFDQTQQLFYVDLLLGDGQARVTFFVHHSIADGRHGSAILI
                                              :**   *  : *   :.    . ::**.:**.:*   :: 

MMAR_1768|M.marinum_M               ELLSRYTDVVTTGDPGPITPEPAPQPAEDLLKRRGIKQSALTGFERFLPL
MUL_2011|M.ulcerans_Agy99           ELLSRYTDVVTTGDPGPITPEPAPQPAEDLLKRRGIKQSALTGFERFLPL
Mb2964|M.bovis_AF2122/97            ELFSRYTDAVTTGDPGPITPQPTPLSMEAVLAQRGIRKQGLSGAERFMSV
Rv2939|M.tuberculosis_H37Rv         ELFSRYTDAVTTGDPGPITPQPTPLSMEAVLAQRGIRKQGLSGAERFMSV
MLBr_02349|M.leprae_Br4923          ELFSRYTDVVTTGDPGPIIPQATPLSMEAVLQQRGVKKHALSGAERFMSV
Mflv_3386|M.gilvum_PYR-GCK          ELFSTYTDLVTTGTARQAPVAPAPAALETILSDRGVEKKLRSGLERLLAA
Mvan_3119|M.vanbaalenii_PYR-1       ELFSTYTDLVTTGTTKPVEVHPAPEPLEVILANRGVEKRTRSGLERLLAA
MAB_2035|M.abscessus_ATCC_1997      EFWSLYVQRVEEGQFPPILTQKFPQSGEYFLN-----RTQYPGADPSVKA
                                    *: * *.: *  *          * . * .*      :   .* :  :  

MMAR_1768|M.marinum_M               LFAYDLPP--IAEEMRKFEAP-EPVPVTRCRLTSQETADLVSFSRDNGLS
MUL_2011|M.ulcerans_Agy99           LFAYDLPP--IAEEMRKFEAP-EPVPVTRCRLTSQETADLVSFSRDNGLS
Mb2964|M.bovis_AF2122/97            MYAYEIPATETPAVLAHPGLP-QAVPVTRLWLSKQQTSDLMAFGREHRLS
Rv2939|M.tuberculosis_H37Rv         MYAYEIPATETPAVLAHPGLP-QAVPVTRLWLSKQQTSDLMAFGREHRLS
MLBr_02349|M.leprae_Br4923          MYAYDLPATGTPAVLAEPGLP-QAVPVTRLWLTKQETSDLAAFGREHRLS
Mflv_3386|M.gilvum_PYR-GCK          MFAYDVPPSRRAPAENNPVLP-QRVPMEFCKLSEAETENIIGFCRANKLG
Mvan_3119|M.vanbaalenii_PYR-1       MFVYDLPPSRRAPSDVNPVLP-QLVPMAYCTLSEQDTEKIIAFCRANKLG
MAB_2035|M.abscessus_ATCC_1997      DEVLRVPLWDEAALAQKLPPPREPALAKQMTLEKLGRASLARLGNIESIS
                                      .  :*    .    .   * : .      * .    .:  : . . :.

MMAR_1768|M.marinum_M               FNAVLAAAILLAEWRLRETPHVPIPYCYAVDLRFLLSPPVGATESTNPVG
MUL_2011|M.ulcerans_Agy99           FNAVLAAAILLAEWRLRETPHVPIPYCYAVDLRFLLSPPVGATESTNPVG
Mb2964|M.bovis_AF2122/97            LNAVVAAAILLTEWQLRNTPHVPIPYVYPVDLRFVLAPPVAPTEATNLLG
Rv2939|M.tuberculosis_H37Rv         LNAVVAAAILLTEWQLRNTPHVPIPYVYPVDLRFVLAPPVAPTEATNLLG
MLBr_02349|M.leprae_Br4923          INAVVAAAILMTEWRLRETPHVPIPYVYPVDLRYVLAPPVAPTESTNLLG
Mflv_3386|M.gilvum_PYR-GCK          LNSLLSASILMAEWQLRETPNIPVPYVYPVDLRYLLSPPVSATECTNPVG
Mvan_3119|M.vanbaalenii_PYR-1       LNSLLSAAVLMAEWNVRRTPNIPVPYVYPVDLRYLLSPPVSATESTNPVG
MAB_2035|M.abscessus_ATCC_1997      INALVSAALIRAHVRAGDP--VPL-YFYPVDLRDCVTPPVAPTEATNLLS
                                    :*::::*::: :. .   .  :*: * *.****  ::***..**.** :.

MMAR_1768|M.marinum_M               LATYLAEIGPDTDITELAADIVATFRADLSDGMIHQSALRSGRILEGTPP
MUL_2011|M.ulcerans_Agy99           LATYLAEIGPDTDITELAADIVATFRADLSDGMIHQSALRSGRILEGTPP
Mb2964|M.bovis_AF2122/97            AASYLAEIGPNTDIVDLASDIVATLRADLANGVIQQSGLHFGTAFEGTPP
Rv2939|M.tuberculosis_H37Rv         AASYLAEIGPNTDIVDLASDIVATLRADLANGVIQQSGLHFGTAFEGTPP
MLBr_02349|M.leprae_Br4923          AAGYLAEIGQDTDIVDLATDIVATLRADLANGVVQQSGLHFGTAFEGTPP
Mflv_3386|M.gilvum_PYR-GCK          IATYLAEISPDTDVVDLARDINDTFKADIADGVIQQSFLHFSPQYVGNPP
Mvan_3119|M.vanbaalenii_PYR-1       IATYLAEIEKGTDIAELARDINDTYKKDIAEGVIQQSFLHFSPQYVGNPP
MAB_2035|M.abscessus_ATCC_1997      NA-WFGDVEIGPDLVTLARKIHVQFDRDLADGTIHRTRVRNEPTKLLADK
                                     * ::.::  ..*:. ** .*      *:::* :::: ::          

MMAR_1768|M.marinum_M               GLPPFVLCTNVSTLPPIRTPEDVELVDFHSRIHCAMDVPFGFYACSIATD
MUL_2011|M.ulcerans_Agy99           GLPPFILCTNVSTLPPIRTPEDVELVDFHSRIHCAMDVPFGFYACSIATD
Mb2964|M.bovis_AF2122/97            GLPPLVFCTDATSFPTMRTPPGLEIEDIKGQFYCSISVPLDLYSCAVYAG
Rv2939|M.tuberculosis_H37Rv         GLPPLVFCTDATSFPTMRTPPGLEIEDIKGQFYCSISVPLDLYSCAVYAG
MLBr_02349|M.leprae_Br4923          GLPPLVFCTDATAFPTMRTPPDLAIEDIQGRFYCSISVPLDLYSCGVYEG
Mflv_3386|M.gilvum_PYR-GCK          GLPDVVMFTDNGIVPPMRMPPDMELAASHGELYFAVGAGIEIYTSKIFAG
Mvan_3119|M.vanbaalenii_PYR-1       GLPDVVMFTDNGIVPPLRTPPDMEVAASHGEFYFAVGAGIEIYTSKIFNG
MAB_2035|M.abscessus_ATCC_1997      SFGGAIHATQLGRIRVPRLPGNLVVDDITSSHASALGPAIYTFLYGREVS
                                    .:   :  *:   .   * * .: :    .    ::.  :  :      .

MMAR_1768|M.marinum_M               RLSIELHGSIPAP---QLLLDAIRDILCSVPSEYGLFME---
MUL_2011|M.ulcerans_Agy99           RLSIELHGSIPAP---QLLLDAIRDILCSVPSEYGLFME---
Mb2964|M.bovis_AF2122/97            QLIIEHHGHIAEP---GKSLEAIRSLLCTVPSEYGWIME---
Rv2939|M.tuberculosis_H37Rv         QLIIEHHGHIAEP---GKSLEAIRSLLCTVPSEYGWIME---
MLBr_02349|M.leprae_Br4923          QLIIEHHGHIEEP---AKALEAIRSLLCTVPSEYGWIME---
Mflv_3386|M.gilvum_PYR-GCK          RLMIEYHSHGPAP---EKSVQTIETLLRGIAARQAAARVS--
Mvan_3119|M.vanbaalenii_PYR-1       QLMIEYHSHGPDR---EKSVAAIEEQLRAVVARQSGVG----
MAB_2035|M.abscessus_ATCC_1997      VYTIDSLNQRLRVGFLAGSYEKSDELLAYIEDELTAAIDARI
                                       *:  .                  *  :  .