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VLTELRIESLGAISVATAEFDRGFTVLTGETGTGKTMVVTGLHLLGGARADATRVRSGADRAVVEGRFTT TDLDDATVAGLQAVLDSSGAERDEDGSVIALRSISRDGPSRAYLGGRGVPAKSLSGFTNELLTLHGQNDQ LRLMRPDEQRGALDRFAAAGEAVQRYRKLRDAWLTARRDLVDRRNRARELAQEADRLKFALNEIDTVDPQ PGEDVALVADIARLSELDTLREAATTARATLCGTPDADAFDRGAVDSLGRARAALQSSDDAALRGLAEQV GEALTVVVDAVAELGAYLDELPADASALDAKLARQAQLRTLTRKYAADIDGVLRWADEARARLAQLDVSE EGLAALERRTGELAHELGQAAVDLSTIRRKAAKRLAKEVSAELSALAMADAEFTIGVTTELADHGDPVAL ALASGELARAGADGVDAVEFGFVAHRGMTVLPLAKSASGGELSRVMLSLEVVLATSRKQAAGTTMVFDEI DAGVGGWAAVQIGRRLARLARTHQVIVVTHLPQVAAYADVHLMVQRTGRDGASGVRRLTSEDRVAELARM LAGLGDSDSGRAHARELLETAQNDELT
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv1696 | recN | - | 100% (587) | PROBABLE DNA REPAIR PROTEIN RECN (RECOMBINATION PROTEIN N) |
M. tuberculosis H37Rv | Rv2922c | smc | 1e-10 | 24.95% (469) | chromosome partition protein Smc |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1722 | recN | 0.0 | 100.00% (587) | DNA repair protein recN (recombination protein N) |
M. gilvum PYR-GCK | Mflv_3507 | - | 0.0 | 70.69% (597) | DNA repair protein RecN |
M. leprae Br4923 | MLBr_01360 | recN | 0.0 | 76.06% (589) | recombination and DNA repair |
M. abscessus ATCC 19977 | MAB_2361 | - | 0.0 | 67.75% (586) | DNA repair protein RecN |
M. marinum M | MMAR_2501 | recN | 0.0 | 80.00% (585) | DNA repair protein, RecN |
M. avium 104 | MAV_3075 | recN | 0.0 | 76.78% (590) | DNA repair protein RecN |
M. smegmatis MC2 155 | MSMEG_2423 | smc | 1e-09 | 24.09% (469) | chromosome segregation protein SMC |
M. thermoresistible (build 8) | TH_1548 | recN | 0.0 | 70.34% (590) | PROBABLE DNA REPAIR PROTEIN RECN (RECOMBINATION PROTEIN N) |
M. ulcerans Agy99 | MUL_1685 | recN | 0.0 | 80.17% (585) | DNA repair protein, RecN |
M. vanbaalenii PYR-1 | Mvan_3288 | - | 0.0 | 71.86% (590) | DNA repair protein RecN |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3507|M.gilvum_PYR-GCK -MLAEIRIEALGAIN-AATAEFDGGLTVLTGETGAGKTMVVTGLHLLGGA Mvan_3288|M.vanbaalenii_PYR-1 -MLAEIRIEALGAIS-AATAEFDGGLTVLTGETGAGKTMVVTGLHLLGGA TH_1548|M.thermoresistible__bu -VLSEIRIESLGAIS-SATAEFDRGLTVLTGETGTGKTMVVTGLHLLGGG Rv1696|M.tuberculosis_H37Rv -MLTELRIESLGAIS-VATAEFDRGFTVLTGETGTGKTMVVTGLHLLGGA Mb1722|M.bovis_AF2122/97 -MLTELRIESLGAIS-VATAEFDRGFTVLTGETGTGKTMVVTGLHLLGGA MMAR_2501|M.marinum_M -MLTEIRIESLGAIS-AATAEFDRGLTVLTGETGTGKTMVVTGLHLLGGA MUL_1685|M.ulcerans_Agy99 -MLTEIRIESLGAIS-AATAEFDRGLTVLTGETGTGKTMVVTGLHLLGGA MLBr_01360|M.leprae_Br4923 -MLTEIRIESLGAIS-VATAEFDRGLTVLTGETGTGKTMVVTGLHLLGGA MAV_3075|M.avium_104 -MLTEIRIESLGAIS-AAVGEFDRGLTVLTGETGTGKTMVVTGLHLLGGA MAB_2361|M.abscessus_ATCC_1997 -MLTEIRIESLGAIP-AATAEFDSGLTVLTGETGAGKTMVVTSLHLLGGA MSMEG_2423|M.smegmatis_MC2_155 MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE * .: ::.: :: :. .*: *:* :.* .*:**: ** .* : * Mflv_3507|M.gilvum_PYR-GCK RADATKVRSGSDRAVVEGRFTTTEVGDAVSARVDGILDSSGAERDDDGSV Mvan_3288|M.vanbaalenii_PYR-1 RADATKVRSGADRAVVEGRFTTAEVGDAVAAQVDGILDSSGAERDDDGSV TH_1548|M.thermoresistible__bu RADPTRVRSGAQRAVVEGRFSTAELLDEAAARVDDILAASGAERDEDGTV Rv1696|M.tuberculosis_H37Rv RADATRVRSGADRAVVEGRFTTTDLDDATVAGLQAVLDSSGAERDEDGSV Mb1722|M.bovis_AF2122/97 RADATRVRSGADRAVVEGRFTTTDLDDATVAGLQAVLDSSGAERDEDGSV MMAR_2501|M.marinum_M RADANRVRSGADRAIVEGRFTTVDLDQSATAHLDHMLDASGADRDEDGSV MUL_1685|M.ulcerans_Agy99 RADANRVRSGADRAIVEGRFTTVDLDQSATAHLDHMLDASGADRDEDGSV MLBr_01360|M.leprae_Br4923 RADASRVRSGANRAVVEGRFTTTDLDDVVVAQLDGILNASGSERDEDGSV MAV_3075|M.avium_104 RADATRVRSGADRAIVEGRFTTTDLDEALVVRLDEMLDASGAERDEDGSV MAB_2361|M.abscessus_ATCC_1997 RADANRVRAGADRAVVEGRFLTADPLGAEPAEVTEVLDSSGAQRDDDGSV MSMEG_2423|M.smegmatis_MC2_155 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVT--LTIDNSDNALPIEYSEV :. . . : .:. * . . : :..: : . * Mflv_3507|M.gilvum_PYR-GCK IAARSVSRDGPSRAYLGGRSVPAKSLSGFTN--------ELLTLHGQNDQ Mvan_3288|M.vanbaalenii_PYR-1 IAARSVSRDGPSRAYLGGRSVPAKSLSGFTN--------ELLTLHGQNDQ TH_1548|M.thermoresistible__bu IAARTVSRDGPSRAYLGGRSVPAKSLGNFTG--------ELLTVHGQNDQ Rv1696|M.tuberculosis_H37Rv IALRSISRDGPSRAYLGGRGVPAKSLSGFTN--------ELLTLHGQNDQ Mb1722|M.bovis_AF2122/97 IALRSISRDGPSRAYLGGRGVPAKSLSGFTN--------ELLTLHGQNDQ MMAR_2501|M.marinum_M IALRSVSSSGPSRAYLGGRSVPAKSLSNFTN--------ELLALHGQNDQ MUL_1685|M.ulcerans_Agy99 IALRSVSSSGPSRAYLGGRSVPAKSLSNFTN--------ELLALHGQNDQ MLBr_01360|M.leprae_Br4923 IVLRSVSRDGPSRSYLGGRSVPAKSLGSFTT--------ELLALHGQNDQ MAV_3075|M.avium_104 IALRSVNRDGPSRAYLGGRSVPAKSLGDFTA--------ELLTLHGQNDQ MAB_2361|M.abscessus_ATCC_1997 IAARSVTSDGRSRAYLGGRSVPAKSLASFTA--------GLLTVHGQNDQ MSMEG_2423|M.smegmatis_MC2_155 SITRRMFRDGAGEYEINGASCRLMDVQELLSDSGIGREMHVIVGQGKLSE * : .* .. :.* . .: : ::. :*: .: Mflv_3507|M.gilvum_PYR-GCK LRLMRPDEQRNALDRYA--------------DVTRRLDRYRSARDAWLEA Mvan_3288|M.vanbaalenii_PYR-1 LRLMRPDEQRAALDRYA--------------DVATQLHRYRTARDSWLEA TH_1548|M.thermoresistible__bu LRLMRPDEQRAALDRFA--------------DLGGRLQRYQLLHQQWLDA Rv1696|M.tuberculosis_H37Rv LRLMRPDEQRGALDRFA--------------AAGEAVQRYRKLRDAWLTA Mb1722|M.bovis_AF2122/97 LRLMRPDEQRGALDRFA--------------AAGEAVQRYRKLRDAWLTA MMAR_2501|M.marinum_M LRLMRPEEQRGALDRFA--------------TSASALQRYRKLRDTWLSA MUL_1685|M.ulcerans_Agy99 LRLMRPEEQRGALDRFA--------------TSASALQRYRKLRDTWLSA MLBr_01360|M.leprae_Br4923 LRLVRPEEQRAALDRYA--------------AAGPSCERYRELRDAWLLA MAV_3075|M.avium_104 LRLMRPEEQCGALDRFA--------------KAGPALERYTKLRDAWLSA MAB_2361|M.abscessus_ATCC_1997 LRLMRPEQQLAALDKFASD------------SIEALLTTYRKLREEWLAA MSMEG_2423|M.smegmatis_MC2_155 ILESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMAANLARLTDLTTEL : **::: ::. * : Mflv_3507|M.gilvum_PYR-GCK RRDLE--------DRRRRTRELAQEADRLHFALNEIDVVDPKPGEDEALV Mvan_3288|M.vanbaalenii_PYR-1 KRDLD--------DRRRRAREMAQEADRLQFALNEIDVIDPHSGEDDALV TH_1548|M.thermoresistible__bu RRDLA--------DRRERARELAQEADRLTFALNEIDAVAPQPGEDDALA Rv1696|M.tuberculosis_H37Rv RRDLV--------DRRNRARELAQEADRLKFALNEIDTVDPQPGEDVALV Mb1722|M.bovis_AF2122/97 RRDLV--------DRRNRARELAQEADRLKFALNEIDTVDPQPGEDVALV MMAR_2501|M.marinum_M RRDLL--------DRRNRARELAQEADRLQFALDEIDTVDPQPGEDDALV MUL_1685|M.ulcerans_Agy99 RRDLL--------DRRNRARELAQEADRLQFALDEIDTVDPQPGEDDALV MLBr_01360|M.leprae_Br4923 RSDLI--------DRRNRIRELVQEADRLKFALSEIDSVDPQPGEDNALV MAV_3075|M.avium_104 RRDLA--------DRRNRMRELALEADRLTFALGEIDAVDPQPGEDDALV MAB_2361|M.abscessus_ATCC_1997 RRDLI--------DRTNRVRELAQEADRLGFALNEIDTVDPKPGEDDQLT MSMEG_2423|M.smegmatis_MC2_155 RRQLKPLGRQAEMARRAATIQADLRDARLRLAADDLVRRQVEFQNTNQAE : :* * : . ** :* .:: . : Mflv_3507|M.gilvum_PYR-GCK ADIRRLSELDALRDAVQTARAALAGD-GDDSAHDGFSAAGAVGQARSALE Mvan_3288|M.vanbaalenii_PYR-1 AEIRRLSELDALREAVQTARAALSGE-SDD----GFSAAHAVGQARSALE TH_1548|M.thermoresistible__bu ENIRRLSELDALREAARTARARLSGALDDDAAVDATSALDQVGQAKAALE Rv1696|M.tuberculosis_H37Rv ADIARLSELDTLREAATTARATLCG--TPDADAFDRGAVDSLGRARAALQ Mb1722|M.bovis_AF2122/97 ADIARLSELDTLREAATTARATLCG--TPDADAFDRGAVDSLGRARAALQ MMAR_2501|M.marinum_M ADIARLSELDTLREAASAARAALSG---ASEEAFGTGAAECLGRARAALE MUL_1685|M.ulcerans_Agy99 ADIARLSELDTLREAASAARAALSG---ASEEAFGTGAAECLGRARAALE MLBr_01360|M.leprae_Br4923 ADIVRLSELDMLREVAVNARAALSGA-LDDMDVSGSNAVACMGQAKAALE MAV_3075|M.avium_104 AEIMRLSELDTLREAAAAARAALS---ADDADGSGLSAVDTLGKARAALE MAB_2361|M.abscessus_ATCC_1997 ADIHRLSELDALRDAAASAREALAGADADGDAHDSHSAIDRIARAKALVE MSMEG_2423|M.smegmatis_MC2_155 TALRKEHEELTVRLQSATVELQAHEAAVAELTRRAEAAQQTWFRASALAE : : * :* .. * :* : : Mflv_3507|M.gilvum_PYR-GCK --------NTDDVALKSLAEQLG-----AALTVVVDVSAELG-HFLAELP Mvan_3288|M.vanbaalenii_PYR-1 --------GTDDAPLKALAEQLG-----SALTVLVDVSAELG-GYLDELP TH_1548|M.thermoresistible__bu --------STDDTALRALGARLD-----EALLLIGDVADELG-GYLEGLP Rv1696|M.tuberculosis_H37Rv --------SSDDAALRGLAEQVG-----EALTVVVDAVAELG-AYLDELP Mb1722|M.bovis_AF2122/97 --------SSDDAALRGLAEQVG-----EALTVVVDAVAELG-AYLDELP MMAR_2501|M.marinum_M --------SSDDATLQALAKQVS-----DALAVVSDAAGELG-SYVDALP MUL_1685|M.ulcerans_Agy99 --------SSDDATLQALAKQVS-----DALAVVSDAAGELG-SYVDALP MLBr_01360|M.leprae_Br4923 --------STDDATLRAFADQVG-----EVLTVVVEVGRELG-EYLEELP MAV_3075|M.avium_104 --------STDDPKLLALAGQIG-----EVLTVVVDAAGELA-GFLEELP MAB_2361|M.abscessus_ATCC_1997 --------ATDDATLRALAPQLA-----EALAVVSDVSRELT-AFTDELP MSMEG_2423|M.smegmatis_MC2_155 RVGATVRIATDRAQMLDSEPEMSSGRDPDALEAEAEEVAELEAQLLDELS :* : .: .* : ** *. Mflv_3507|M.gilvum_PYR-GCK SDASTLETKLARQAELRTLTRKYAADIDGVLAWAVEARERLS----ALDV Mvan_3288|M.vanbaalenii_PYR-1 TDTSSLETKLARQAELRTLTRKYAADVDGVLAWAGEARDRLA----ALDV TH_1548|M.thermoresistible__bu TDASTLETSLARQSELRTLTRKYAADIDGVLQWAQQARDRLA----QLDV Rv1696|M.tuberculosis_H37Rv ADASALDAKLARQAQLRTLTRKYAADIDGVLRWADEARARLA----QLDV Mb1722|M.bovis_AF2122/97 ADASALDAKLARQAQLRTLTRKYAADIDGVLRWADEARARLA----QLDV MMAR_2501|M.marinum_M ADASALDTKLARQAQLRTLTRKYAADIDGVLAWAQDSRARLA----ALDV MUL_1685|M.ulcerans_Agy99 ADASALDTKLARQAQLRTLTRKYAADIDGVLAWAQDSRARLA----ALDV MLBr_01360|M.leprae_Br4923 VDASALESKLVRQAELCTLTRKYAADIDGVLQWARESRERLE----QLDV MAV_3075|M.avium_104 VDASALEAKLARQSELRGLTRKYAADIDGVLAWARESRERLA----QLDV MAB_2361|M.abscessus_ATCC_1997 SDASTLEEKLARQGQLRTLTRKYAADLNGVIAWAKEARTRLA----EVDT MSMEG_2423|M.smegmatis_MC2_155 EARIALETARAELAEREQIAADAERAHMAAARAEADRREGLARLAGQVDT :*: .. .: :: . .. : * * :*. Mflv_3507|M.gilvum_PYR-GCK SEETLTGLQRRVDELQSAVVAAAQDVTKVRSKAAKGLSKAVTAELAGLAM Mvan_3288|M.vanbaalenii_PYR-1 SEETLAGLERRVEELQATVVAAAQDLTKVRVKAAKGLSKAVTAELSGLAM TH_1548|M.thermoresistible__bu SEEALGELERRVDELQAQVVSAAMDLTKARTRAAGRLAKAVTAELAGLAM Rv1696|M.tuberculosis_H37Rv SEEGLAALERRTGELAHELGQAAVDLSTIRRKAAKRLAKEVSAELSALAM Mb1722|M.bovis_AF2122/97 SEEGLAALERRTGELAHELGQAAVDLSTIRRKAAKRLAKEVSAELSALAM MMAR_2501|M.marinum_M SEEGLAALQRRAGELEHEVAQAAAELSKTRARAAKRLAKEVTAELSALAM MUL_1685|M.ulcerans_Agy99 SEEGLAALQRRAGELEHEVAQAAAELSKTRAKAAKRLAKEVTAELSALAM MLBr_01360|M.leprae_Br4923 SYERLAGVESRVDELERQLSQAAVDLSKLRRDAANRLAKEVTAELSALAM MAV_3075|M.avium_104 SEEGLSALAARVEELGRELAGAAADLSTIRRKAAKRLAKEVTAELSGLAM MAB_2361|M.abscessus_ATCC_1997 SEETLNAIAARVDRLGAELATAATGLSKARAKAAKALSKAVTAELAGLAM MSMEG_2423|M.smegmatis_MC2_155 MRTRVESIDEGVLRLSVSIEEAAAKAEHAQAEFEDVQSRVGELDAGEVGL : : . .* : ** : :: : . :.: Mflv_3507|M.gilvum_PYR-GCK SGAQFAITVAPLAARA----DDSAPLELPSGVTVHAGRDGVDAVEFGFAA Mvan_3288|M.vanbaalenii_PYR-1 AGADFAISVTPLPARA----DDSAPLALPSGVTVHAGHDGVDAVEFGFAA TH_1548|M.thermoresistible__bu ADAEFTVTVGPLTARP----DDTAPLTMPDGQTVHAGRHGVDGVEFGFTA Rv1696|M.tuberculosis_H37Rv ADAEFTIGVTTELADH----GDPVALALASGELARAGADGVDAVEFGFVA Mb1722|M.bovis_AF2122/97 ADAEFTIGVTTELADH----GDPVALALASGELARAGADGVDAVEFGFVA MMAR_2501|M.marinum_M ADAEFTIAVGVEVADE----DDAAALTLPTGERVRAGGDGVDLVEFGFAA MUL_1685|M.ulcerans_Agy99 ADAEFTIVVGVEVADE----DDAAALTLPTGERVRAGGDGVDLVEFGFAA MLBr_01360|M.leprae_Br4923 VDAEFTISVTTDLIPL-TDYKRSAAVTLPSGGVARAGADGVDQVEFGFAA MAV_3075|M.avium_104 ADAQFSIDVSTDVVPAGSGSDDAAVLTLPSGERVRAGADGIDQVEFGFAA MAB_2361|M.abscessus_ATCC_1997 DRAAFSIGVEPIAARP----DDSAPLTLPSGQTVHAGSSGTDVVEFGFAA MSMEG_2423|M.smegmatis_MC2_155 DEHHDRTVAALRLADER--VAELQAAERAAERQVASLRARIEALSVGLDR . . . : : :..*: Mflv_3507|M.gilvum_PYR-GCK HGGSDLLPLNKSASG-----GELSRVMLALEVVLSAS------------T Mvan_3288|M.vanbaalenii_PYR-1 HGGSDLLPLNKSASG-----GELSRVMLALEVVLSAS------------T TH_1548|M.thermoresistible__bu HRGTDVLPLAKSASG-----GELSRVMLALEVVLAAS------------A Rv1696|M.tuberculosis_H37Rv HRGMTVLPLAKSASG-----GELSRVMLSLEVVLATSR---------KQA Mb1722|M.bovis_AF2122/97 HRGMTVLPLAKSASG-----GELSRVMLSLEVVLATSR---------KQA MMAR_2501|M.marinum_M HRGMTVLPLAKSASG-----GELSRVMLALEVVLAAS------------A MUL_1685|M.ulcerans_Agy99 HRGMTVLPLAKSASG-----GELSRVMLALEVVLAAS------------A MLBr_01360|M.leprae_Br4923 HRGMTVLPLAKSASG-----GELSRVMLALEVVLATS------------A MAV_3075|M.avium_104 HRGMDRLPLAKSASG-----GELSRVMLALEVVLAASR---------KET MAB_2361|M.abscessus_ATCC_1997 HRDNPMLPLAKSASG-----GELSRVMLALEVVLAAS------------T MSMEG_2423|M.smegmatis_MC2_155 RDGAAWLQKNHSGGGLFGSIGDFLRVQPGYEVAVAAVLGAAADALAAENF : . * :*..* *:: ** . **.::: Mflv_3507|M.gilvum_PYR-GCK EGTTMVFDEVDAGVGGRAAVQIGRR--------------------LARLA Mvan_3288|M.vanbaalenii_PYR-1 EGTTMVFDEVDAGVGGRAAVQIGRR--------------------LARLA TH_1548|M.thermoresistible__bu EGTTMVFDEVDAGVGGRAAVQIGRR--------------------LARLA Rv1696|M.tuberculosis_H37Rv AGTTMVFDEIDAGVGGWAAVQIGRR--------------------LARLA Mb1722|M.bovis_AF2122/97 AGTTMVFDEIDAGVGGWAAVQIGRR--------------------LARLA MMAR_2501|M.marinum_M AGTTMVFDEVDAGVGGWAAVQIGRR--------------------LARLA MUL_1685|M.ulcerans_Agy99 AGTTMVFDEVDAGVGGWAAVQIGRR--------------------LARLA MLBr_01360|M.leprae_Br4923 AGTTMVFDEVDVGVGGRAAVQIGRR--------------------LARLA MAV_3075|M.avium_104 VGTTMVFDEVDAGVGGRAAVQIGRR--------------------LARLA MAB_2361|M.abscessus_ATCC_1997 AGTTMVFDEVDAGVGGRAAVQIGRR--------------------LAKLA MSMEG_2423|M.smegmatis_MC2_155 GAAAAAVAALKESDGGRAAIVLGDWNAIGSSPQAALPPGATWATDLVSVP .:: .. :. . ** **: :* *. :. Mflv_3507|M.gilvum_PYR-GCK RTHQVIVVTHLPQVAAYADVHLVVEGVGN--------------------- Mvan_3288|M.vanbaalenii_PYR-1 RTHQVIVVTHLPQVAAYADVHLVVEGV----------------------- TH_1548|M.thermoresistible__bu RTHQVIVVTHLPQVAAYADIHLVVDSG----------------------- Rv1696|M.tuberculosis_H37Rv RTHQVIVVTHLPQVAAYADVHLMVQRTG---------------------- Mb1722|M.bovis_AF2122/97 RTHQVIVVTHLPQVAAYADVHLMVQRTG---------------------- MMAR_2501|M.marinum_M RTHQVIVVTHLPQVAAYADVHLMVHGT----------------------- MUL_1685|M.ulcerans_Agy99 RTHQVIVVTHLPQVAAYADVHLMVHGT----------------------- MLBr_01360|M.leprae_Br4923 RTHQVIVVTHLPQVAAYADVHLVVHSAG---------------------- MAV_3075|M.avium_104 RTHQVIVVTHLPQVAAYADVHLVVHGAG---------------------- MAB_2361|M.abscessus_ATCC_1997 HTHQVIVVTHLPQVAAFADIHLTVDRVN---------------------- MSMEG_2423|M.smegmatis_MC2_155 DRLRGAVTAMLTGVAVVPDMAAGLALVSSRPELRAVTTEGDLVGPGWVSG : *.: *. **. .*: : Mflv_3507|M.gilvum_PYR-GCK --DGAGSGDGKKARAKSSGVRRLDDDDRVAELARMLAGLGESDSGRAHAR Mvan_3288|M.vanbaalenii_PYR-1 ----AGRDDGRKARAKSSGVRRLDDDDRVAELARMLAGLGESDSGRAHAR TH_1548|M.thermoresistible__bu -----GRDADNRG---ASRVQRLDEEGRVAELARMLAGLGETDSGRAHAR Rv1696|M.tuberculosis_H37Rv -------------RDGASGVRRLTSEDRVAELARMLAGLGDSDSGRAHAR Mb1722|M.bovis_AF2122/97 -------------RDGASGVRRLTSEDRVAELARMLAGLGDSDSGRAHAR MMAR_2501|M.marinum_M -------------KGGASEVRRLSDDERVGELARMLAGLGESDSGRAHAR MUL_1685|M.ulcerans_Agy99 -------------KGGASEVRRLSDDERVGELARMLAGLGESDSGRAHAR MLBr_01360|M.leprae_Br4923 -------------LDGASDVRRLAGDDRVAELARMLAGLGESDSGRAHAR MAV_3075|M.avium_104 -------------PRGTSVVRRVTGDERVAELARMLAGLGESDSGRAHAR MAB_2361|M.abscessus_ATCC_1997 --------------SKGSGVRRLDDEDRVAELARMLAGLGDSDTGRAHAR MSMEG_2423|M.smegmatis_MC2_155 GSDRKPSTLEIASEIDKARAELEQAERQTSELGAALSGALAEQSARQDAA : .. : :..**. *:* ::.* .* Mflv_3507|M.gilvum_PYR-GCK DLLDAARKDRAAE------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 ELLDAARAERAAAD------------------------------------ TH_1548|M.thermoresistible__bu ELLEAAQRERAEVSV----------------------------------- Rv1696|M.tuberculosis_H37Rv ELLETAQNDELT-------------------------------------- Mb1722|M.bovis_AF2122/97 ELLETAQNDELT-------------------------------------- MMAR_2501|M.marinum_M ELLDTARNDKD--------------------------------------- MUL_1685|M.ulcerans_Agy99 ELLDTARNDKD--------------------------------------- MLBr_01360|M.leprae_Br4923 ELLDAARKDKS--------------------------------------- MAV_3075|M.avium_104 ELLDAAQKDEI--------------------------------------- MAB_2361|M.abscessus_ATCC_1997 ELLDAARAERT--------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 EQALAALNESDAAISAIYEQLARLGQEARGAHQEWQRLIKQRDELEAGRT : :* : Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 KTVEELRELESRLSNAEQTPMFDIEPVDRQETVAAAEAARAVEVEARLAV Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 RTAEERANAVRGRADSLRRAAAAEREARVRAQRAREAREYAARVAAAVSE Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 CGRQIAGKLSAVVAAAARSRDELATERQLRVNALGEIREEVTALNNRINT Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 LTDALHRDEMAKAQAQLRIEQLEAQVLEQFGMSAGDLVAEYGPQVALPPS Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 ELEMAEYEQAKERGEQVTAPAPMPFDRATQERRAKRAERELAELGRVNPL Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 ALEEFAALEERYNFLSTQLEDVKAARADLLDVIADVDNRILQVFTEAYAD Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 VEREFEQVFATLFPGGEGRLLLTDPSDMLTTGIEVEARPPGKKIKRLSLL Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 SGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLISLFEQLR Mflv_3507|M.gilvum_PYR-GCK ------------------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 ------------------------------------------------- TH_1548|M.thermoresistible__bu ------------------------------------------------- Rv1696|M.tuberculosis_H37Rv ------------------------------------------------- Mb1722|M.bovis_AF2122/97 ------------------------------------------------- MMAR_2501|M.marinum_M ------------------------------------------------- MUL_1685|M.ulcerans_Agy99 ------------------------------------------------- MLBr_01360|M.leprae_Br4923 ------------------------------------------------- MAV_3075|M.avium_104 ------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 ------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 EKSQLIVITHQKPTMEIADALYGVTMRGDGITTVISQRMRGQELVSNPS