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SQVGHRAGGRQIAQLALPALGVLAAEPLYLLFDIAVVGRLGAISLAGLAIGSLVLGLVGSQATFLSYGTT ARAARRYGAGNRVAAVTEGVQATWLALGLGALVVVVVEATATPLVSAIASGDGITAAALPWLRIAILGTP AILVSLAGNGWLRGVQDTVRPLRYVVAGFGSSALLCPLLVYGWLGLPRWGLTGSAVANLVGQWLAALLFA GALLAERVSLRPDRAVLGAQLMMARDLIVRTLAFQVCYVSAAAVAARFGAAALAAHQVVLQLWGLLALVL DSLAIAAQSLVGAALGAGDAGHAKAVAWRVTAFSLLAAGILAAALGLGSSVLPGLFTDDRSVLAAIGVPW WFMVVQLPFAGIVFAVDGVLLGAGDAAFMRTATVASALVGFLPLVWLSLAYGWGLAGIWSGLGTFIVLRL IFVGWRAYSGRWAVTGAA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2836c | dinF | - | 100% (439) | POSSIBLE DNA-DAMAGE-INDUCIBLE PROTEIN F DINF |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2861c | dinF | 0.0 | 99.77% (439) | DNA-damage-inducible protein F |
M. gilvum PYR-GCK | Mflv_4036 | - | 1e-180 | 72.56% (430) | MATE efflux family protein |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_3128c | - | 1e-172 | 71.90% (427) | DNA-damage-inducible protein F |
M. marinum M | MMAR_1897 | dinF | 0.0 | 83.75% (437) | DNA-damage-inducible protein F DinF |
M. avium 104 | MAV_5113 | - | 2e-05 | 25.44% (401) | NADH dehydrogenase subunit n |
M. smegmatis MC2 155 | MSMEG_2631 | - | 0.0 | 74.83% (433) | MATE efflux family protein |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_2125 | dinF | 0.0 | 83.52% (437) | DNA-damage-inducible protein F DinF |
M. vanbaalenii PYR-1 | Mvan_2317 | - | 1e-178 | 72.06% (433) | MATE efflux family protein |
CLUSTAL 2.0.9 multiple sequence alignment Rv2836c|M.tuberculosis_H37Rv ---MSQVGHR----------------AGGRQIAQLALPALGVLAAEPLYL Mb2861c|M.bovis_AF2122/97 ---MSQVGHR----------------AGGRQIAQLALPALGVLAAEPLYL MMAR_1897|M.marinum_M ---MGPDAGRP--------------DAGGRKIAALALPALGVLAAEPLYL MUL_2125|M.ulcerans_Agy99 ---MGPDAGRP--------------DAGGRKIAALALPALGVLAAEPLYL Mflv_4036|M.gilvum_PYR-GCK ---MADP----------------VAPATGRRIAGLAFPALGVLAAEPVYL Mvan_2317|M.vanbaalenii_PYR-1 ---MAEP----------------VAPASSRRIAALAFPALGVLAAEPIYL MSMEG_2631|M.smegmatis_MC2_155 ---MADAAGDLPGGPDDDAQGAALTQATGRRIAKLAFPALGVLAAEPIYL MAB_3128c|M.abscessus_ATCC_199 ---MTDATGIAG------------MPGLARRIISLALPALGVLAAEPLYL MAV_5113|M.avium_104 MCGIAAVFGVRQTVHVGWLLPLSGLQLDLDPVGGFFMALIGGVAVPVGFY : : : :. :* :*. : Rv2836c|M.tuberculosis_H37Rv LFDIAVVGRLGAISLAGLAIGSLVLGLVGSQATFLSYG------TTARAA Mb2861c|M.bovis_AF2122/97 LFDIAVVGRLGAISLAGLAIGSLVLGLVGSQATFLSYG------TTARAA MMAR_1897|M.marinum_M LFDTAVIGRLGALALAGLAIGSLVLGLVGSQATFLSYG------TTARSA MUL_2125|M.ulcerans_Agy99 LFDTAVIGRLGALALAGLAIGSLVLGLVGSQATFLSYG------TTARSA Mflv_4036|M.gilvum_PYR-GCK LFDLAIVGRLGALSLAGLAIGALIMGVLSSQLTFLSYG------TTARAA Mvan_2317|M.vanbaalenii_PYR-1 LFDLAVIGRLGALNLAGLAIGALIMGVLSSQLTFLSYG------TTARAA MSMEG_2631|M.smegmatis_MC2_155 LFDLAIVGRLGAVSLAGLAIGGLVLGLVNSQGTFLSYG------TTARSA MAB_3128c|M.abscessus_ATCC_199 LFDIAMVGRLGAVPLAGLAVGGLVLSLVGTQLTFLSYG------TTARAA MAV_5113|M.avium_104 SIGYARREHLGRVSLAMLPLFVAAMMLVPAAGSVTTFLLAWELMATASLV :. * :** : ** *.: : :: : :. :: :** . Rv2836c|M.tuberculosis_H37Rv RRYGAGNRVAAVTEG------VQATWLALGLGALVVVVVEAT-------- Mb2861c|M.bovis_AF2122/97 RRYGAGNRVAAVTEG------VQATWLALGLGALVVVVVEAT-------- MMAR_1897|M.marinum_M RHYGAGDRVAAVAEG------VQATWLAVALGLLTILVVQIA-------- MUL_2125|M.ulcerans_Agy99 RHYGAGDRVAAVAEG------VQATWLAVALGLLTILVVQIA-------- Mflv_4036|M.gilvum_PYR-GCK RFYGAGDRNAAVEEG------VQATWLAVGIGTVIVAAVQVT-------- Mvan_2317|M.vanbaalenii_PYR-1 RFYGAGNRTAAVEEG------VQATWLALGIGTTIVVAVQLT-------- MSMEG_2631|M.smegmatis_MC2_155 RFYGAGDRTSAVAEG------VQATWLALGLGLLIIAVVEAV-------- MAB_3128c|M.abscessus_ATCC_199 RRFGSGDRPGAVHEG------VQATWLALLIGAVVVLVVHAV-------- MAV_5113|M.avium_104 LVLAQHTRPEVRSAGLFYAVMTQLGFVAILIGLMVLSAAGGADRFADLTR . * . * .* ::*: :* : .. . Rv2836c|M.tuberculosis_H37Rv ----ATPLVSAIA---SGDG-ITAAALPWLRIAILGTPAILVSLAGNGWL Mb2861c|M.bovis_AF2122/97 ----ATPLVSAIA---SGDG-ITAAALPWLRIAILGTPAILVSLAGNGWL MMAR_1897|M.marinum_M ----AVPLVSVIAGARAGSGDIAGAALPWLRIAILGTPAILISLAGNGWM MUL_2125|M.ulcerans_Agy99 ----AVPLVSVIAGARAGSGDIAGAALPWLWIAILGTPAILISLAGNGWM Mflv_4036|M.gilvum_PYR-GCK ----AVPLVSALAAG----GEIAETALPWVRIASLAVPAILIAAAGNGWM Mvan_2317|M.vanbaalenii_PYR-1 ----AVPLVSVLAGGAD-HGRIAETALPWVRIASLAVPAILIAAAGNGWM MSMEG_2631|M.smegmatis_MC2_155 ----AVPMLSALAAG----GEIAHAALPWLRVAILAAPAILVSMAGNGWM MAB_3128c|M.abscessus_ATCC_199 ----AGPVVRAIAAA----PDVAAQGLGWLRIAIFAAPAILVSLAGNGWM MAV_5113|M.avium_104 VSDGARTVVFVLTMAGFGSKAGLVPLHAWLPRAHPEAPSPVSALMSAAMV * .:: .:: *: * .*: : : . . : Rv2836c|M.tuberculosis_H37Rv RGVQDTVRPLRYVVAGFGSSALLCPLLVYG-----------WLGLPRWGL Mb2861c|M.bovis_AF2122/97 RGVQDTVRPLRYVVAGFGSSALLCPLLVYG-----------WLGLPRWGL MMAR_1897|M.marinum_M RGVQDTVRPLRYVVAGFGLSALLCPLLVYG-----------WLGLPRMEL MUL_2125|M.ulcerans_Agy99 RGVQDTVRPLRYVVAGFGLSALLCPLLVYG-----------WLGLPRMEL Mflv_4036|M.gilvum_PYR-GCK RGVQDTMRPLRYVVVGFGLSAVLCPLLVFG-----------WLGCPELGL Mvan_2317|M.vanbaalenii_PYR-1 RGVQDTMRPLRYVIFGFAVSAVLCPLLVYG-----------WLGAPELGL MSMEG_2631|M.smegmatis_MC2_155 RGVQDTVRPLRYVVLGFAVSAVLCPLLVYG-----------WLGFPRLEL MAB_3128c|M.abscessus_ATCC_199 RGVQNTVRPLRYVIAGFAVSAVLCPVLIYG-----------LAGVPRMGL MAV_5113|M.avium_104 NLGVYGIVRFDLQLLGPGPRWWAITLLVVGGVSAVYGVLQASVATDLKRL . : : : * . .:*: * . * Rv2836c|M.tuberculosis_H37Rv TGSAVANLVGQWLAALLFAGALLAERVSLRPDRAVLGAQLMMARDLIVRT Mb2861c|M.bovis_AF2122/97 TGSAVANLVGQWLAALLFAGALLAERVSLRPDRAVLGAQLMMARDLIVRT MMAR_1897|M.marinum_M AGSAVANLVGQWLAALLFGGALLAERVSLRPDRHILREQLVLARDLIVRT MUL_2125|M.ulcerans_Agy99 AGSAVANLVGQWLAALLFGGALLAERVSLRPDRHILREQLVLARDLIVRT Mflv_4036|M.gilvum_PYR-GCK PGSAVANVAGQYLAAALFCRALFVEKVPLRVRPAVLRAQVVMGRDLILRT Mvan_2317|M.vanbaalenii_PYR-1 PGSAVANVVGQYLAAALFCRALVVEKVPLRLRPPVLRAQVVMGRDLVLRT MSMEG_2631|M.smegmatis_MC2_155 AGSAVANVVGQWLAAGLFMRALLVEKVPLRLRPDVLRVQLVMGRDLLLRS MAB_3128c|M.abscessus_ATCC_199 AGSAVANLVGQWLAAILFLRALHAEHAPLRTDRAVLRAQLVLARDLLVRS MAV_5113|M.avium_104 LAYSTTENMGLITLALGAATLLADSGAHSAATIAMAAALLHLIGHAAFKS . :.:: * * * . . : : : . .:: Rv2836c|M.tuberculosis_H37Rv LAFQVCYVSAAAVAAR---FGAAALAAHQVVLQLWGLLALVLDSLAIAAQ Mb2861c|M.bovis_AF2122/97 LAFQVCYVSAAAVAAR---FGAAALAAHQVVLQLWGLLALVLDSLAIAAQ MMAR_1897|M.marinum_M MAFQACFISAAAVAAR---FGAAALAAHQVVLQLWGFFALVLDSLAIAAQ MUL_2125|M.ulcerans_Agy99 MAFQACFISAAAVAAR---FGAAALAAHQVVLQLWGFFALVLDSLAIAAQ Mflv_4036|M.gilvum_PYR-GCK MAFQACFISAGAVAAR---FGAASVAAHQVVLQLWSFLALVLDSLAIAAQ Mvan_2317|M.vanbaalenii_PYR-1 MAFQACFISAGAVAAR---FGAAAVAAHQVVLQLWNFLALVLDSLAIAAQ MSMEG_2631|M.smegmatis_MC2_155 LAFQACFVSAGAVAAR---FGAAAVAAHQVVLQLWSFLALVLDSLAIAAQ MAB_3128c|M.abscessus_ATCC_199 LAFQACFISAAAVAAR---FGAAALAAHQVVLQMWSFLALVLDSLAIAAQ MAV_5113|M.avium_104 LGFLAAGSVLAATGLRDLDLLGGLARRMPATTALFGVAALGASGLPLGAG :.* .. .*.. * : .. .. ::.. ** ..*.:.* Rv2836c|M.tuberculosis_H37Rv SLVGAALGAGDAGHAKAVAWRVTAFSLLAAGILAAALGLGSSVLPGLFTD Mb2861c|M.bovis_AF2122/97 SLVGAALGAGDAGHAKAVAWRVTAFSLLAAGILAAALGLGSSVLPGLFTD MMAR_1897|M.marinum_M SLVGAALGAGDAAHAKWVAWRVTVFSLLAAGMLAAALALGAPVLPALFTD MUL_2125|M.ulcerans_Agy99 SLVGAALGAGDAAHAKWVAWRVTVFSLLAAGMLAAALALGAPVLPALFTD Mflv_4036|M.gilvum_PYR-GCK SLVGAALGAGQLTHAKAVAWRVTIFSAVAGVVLAVVFALGSQLIPSAFTD Mvan_2317|M.vanbaalenii_PYR-1 SLVGAALGAGQLTHAKAVAWRVTIFSTVAGVVLATVFALGSSVFPAVFTD MSMEG_2631|M.smegmatis_MC2_155 SLVGAALGAGQLAHAKSVAWRVTLFSTLAGVVLAVVFAVGASVFPPVFTD MAB_3128c|M.abscessus_ATCC_199 TLVGAALGAGRVPEAKSVAWRVSIFSLGFAVLLAGILALGAPVLPRLFTS MAV_5113|M.avium_104 FVSEWLLVQSLIHAAPQHNTVVALAAPLAVGAVALTTGLGVAAMVKAFGI : * . * *: : :* .:* : * Rv2836c|M.tuberculosis_H37Rv -------DRSVLAAIGVPWWFMVVQLPFAG--IVFAVDGVLLG--AGDAA Mb2861c|M.bovis_AF2122/97 -------DRSVLAAIGVLWWFMVVQLPFAG--IVFAVDGVLLG--AGDAA MMAR_1897|M.marinum_M -------DAAVLAAVTVPWWFLVAQLPFAG--IVFALDGVLLG--AGDAA MUL_2125|M.ulcerans_Agy99 -------DAAVLAAITVPWWFLVAQLPFAG--VVFALDGVLLG--AGDAA Mflv_4036|M.gilvum_PYR-GCK -------DQSVLDRIGVPWWFLVAQLPVAG--IVFAIDGVLLG--AGDAT Mvan_2317|M.vanbaalenii_PYR-1 -------DRSVLDQIGVPWWFLVAQLPVAG--IVFAIDGVLLG--AGDAT MSMEG_2631|M.smegmatis_MC2_155 -------DESVLATIGVPWWFLVAQLPVAG--IVFALDGVLLG--AGDAK MAB_3128c|M.abscessus_ATCC_199 -------DAAVLHEMRVPWWFLVCQLPISG--LVFALDGVLLG--AADAR MAV_5113|M.avium_104 GFLARPRSQPAADAREVPAVMVAGMALAATGCVVVAVAPLVVGSMLGRVL . .. * ::. : :*.*: :::* . . Rv2836c|M.tuberculosis_H37Rv FMRTATVASALVGFLPLVWLSLAYG-WGLAGIWSGLGTFIVLRLIFVGWR Mb2861c|M.bovis_AF2122/97 FMRTATVASALVGFLPLVWLSLAYG-WGLAGIWSGLGTFIVLRLIFVGWR MMAR_1897|M.marinum_M FMRTATVVSALAGFLPLTWLSLVYG-WGLAGIWSGLATFIVLRLIFVGWR MUL_2125|M.ulcerans_Agy99 FMRTATVVSALAGFLPLTWLSLVYG-WGLAGIWSGLATFIVLRLIFVGWR Mflv_4036|M.gilvum_PYR-GCK FMRNATLASALAGFLPLVWLSLAFG-WGLLGIWAGLSTFMVLRLVFVGWR Mvan_2317|M.vanbaalenii_PYR-1 FMRNATLISALVGFLPLIWLSLAFG-WGLLGIWAGLSAFMVLRLVFVGWR MSMEG_2631|M.smegmatis_MC2_155 FMRNATLASAMLGFLPLIWLSLAFG-WGLFGIWSGLSTFMVLRLVFVGWR MAB_3128c|M.abscessus_ATCC_199 FMRNATMISALCGFLPSVWLALVFG-WGLAGIWCGLTLFLVLRLVLVGWR MAV_5113|M.avium_104 TELPASRAVAFTDFGAVLRLPGLHGSIAPGAIAAALAAAVLAAVGLACWR *: *: .* . *. .* . .* ..* :: : :. ** Rv2836c|M.tuberculosis_H37Rv AYSGR-------WAVTGAA------------------------------- Mb2861c|M.bovis_AF2122/97 AYSGR-------WAVTGAA------------------------------- MMAR_1897|M.marinum_M AMSGR-------WALTGTA------------------------------- MUL_2125|M.ulcerans_Agy99 AMSGR-------WALTGTA------------------------------- Mflv_4036|M.gilvum_PYR-GCK ALSGR-------WLVPGTR------------------------------- Mvan_2317|M.vanbaalenii_PYR-1 ALSGR-------WLVPGTR------------------------------- MSMEG_2631|M.smegmatis_MC2_155 AFSGR-------WLVPGTS------------------------------- MAB_3128c|M.abscessus_ATCC_199 ALSGG-------WAVPGTGS------------------------------ MAV_5113|M.avium_104 SRRRSDPVTLPLWACGADELTPRMQYTATSFAEPLQRVFDDVLRPDTDIE : * . Rv2836c|M.tuberculosis_H37Rv -------------------------------------------------- Mb2861c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1897|M.marinum_M -------------------------------------------------- MUL_2125|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4036|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2317|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2631|M.smegmatis_MC2_155 -------------------------------------------------- MAB_3128c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5113|M.avium_104 ITHLTESRYLAEAVTYRTRIADAIEERLYAPVIGAVAAAAQLVRRAHTGS Rv2836c|M.tuberculosis_H37Rv -------------------- Mb2861c|M.bovis_AF2122/97 -------------------- MMAR_1897|M.marinum_M -------------------- MUL_2125|M.ulcerans_Agy99 -------------------- Mflv_4036|M.gilvum_PYR-GCK -------------------- Mvan_2317|M.vanbaalenii_PYR-1 -------------------- MSMEG_2631|M.smegmatis_MC2_155 -------------------- MAB_3128c|M.abscessus_ATCC_199 -------------------- MAV_5113|M.avium_104 VHLYLAYGMLGVLIVLVVAR