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M. tuberculosis H37Rv Rv2836c (dinF)

annotation: POSSIBLE DNA-DAMAGE-INDUCIBLE PROTEIN F DINF
coordinates: 3142309 - 3143628
length: 439

SQVGHRAGGRQIAQLALPALGVLAAEPLYLLFDIAVVGRLGAISLAGLAIGSLVLGLVGSQATFLSYGTT
ARAARRYGAGNRVAAVTEGVQATWLALGLGALVVVVVEATATPLVSAIASGDGITAAALPWLRIAILGTP
AILVSLAGNGWLRGVQDTVRPLRYVVAGFGSSALLCPLLVYGWLGLPRWGLTGSAVANLVGQWLAALLFA
GALLAERVSLRPDRAVLGAQLMMARDLIVRTLAFQVCYVSAAAVAARFGAAALAAHQVVLQLWGLLALVL
DSLAIAAQSLVGAALGAGDAGHAKAVAWRVTAFSLLAAGILAAALGLGSSVLPGLFTDDRSVLAAIGVPW
WFMVVQLPFAGIVFAVDGVLLGAGDAAFMRTATVASALVGFLPLVWLSLAYGWGLAGIWSGLGTFIVLRL
IFVGWRAYSGRWAVTGAA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2836cdinF-100% (439)POSSIBLE DNA-DAMAGE-INDUCIBLE PROTEIN F DINF

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2861cdinF0.099.77% (439) DNA-damage-inducible protein F
M. gilvum PYR-GCKMflv_4036-1e-18072.56% (430) MATE efflux family protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3128c-1e-17271.90% (427) DNA-damage-inducible protein F
M. marinum MMMAR_1897dinF0.083.75% (437) DNA-damage-inducible protein F DinF
M. avium 104MAV_5113-2e-0525.44% (401) NADH dehydrogenase subunit n
M. smegmatis MC2 155MSMEG_2631-0.074.83% (433) MATE efflux family protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_2125dinF0.083.52% (437) DNA-damage-inducible protein F DinF
M. vanbaalenii PYR-1Mvan_2317-1e-17872.06% (433) MATE efflux family protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv2836c|M.tuberculosis_H37Rv        ---MSQVGHR----------------AGGRQIAQLALPALGVLAAEPLYL
Mb2861c|M.bovis_AF2122/97           ---MSQVGHR----------------AGGRQIAQLALPALGVLAAEPLYL
MMAR_1897|M.marinum_M               ---MGPDAGRP--------------DAGGRKIAALALPALGVLAAEPLYL
MUL_2125|M.ulcerans_Agy99           ---MGPDAGRP--------------DAGGRKIAALALPALGVLAAEPLYL
Mflv_4036|M.gilvum_PYR-GCK          ---MADP----------------VAPATGRRIAGLAFPALGVLAAEPVYL
Mvan_2317|M.vanbaalenii_PYR-1       ---MAEP----------------VAPASSRRIAALAFPALGVLAAEPIYL
MSMEG_2631|M.smegmatis_MC2_155      ---MADAAGDLPGGPDDDAQGAALTQATGRRIAKLAFPALGVLAAEPIYL
MAB_3128c|M.abscessus_ATCC_199      ---MTDATGIAG------------MPGLARRIISLALPALGVLAAEPLYL
MAV_5113|M.avium_104                MCGIAAVFGVRQTVHVGWLLPLSGLQLDLDPVGGFFMALIGGVAVPVGFY
                                       :                           :  : :. :* :*.   : 

Rv2836c|M.tuberculosis_H37Rv        LFDIAVVGRLGAISLAGLAIGSLVLGLVGSQATFLSYG------TTARAA
Mb2861c|M.bovis_AF2122/97           LFDIAVVGRLGAISLAGLAIGSLVLGLVGSQATFLSYG------TTARAA
MMAR_1897|M.marinum_M               LFDTAVIGRLGALALAGLAIGSLVLGLVGSQATFLSYG------TTARSA
MUL_2125|M.ulcerans_Agy99           LFDTAVIGRLGALALAGLAIGSLVLGLVGSQATFLSYG------TTARSA
Mflv_4036|M.gilvum_PYR-GCK          LFDLAIVGRLGALSLAGLAIGALIMGVLSSQLTFLSYG------TTARAA
Mvan_2317|M.vanbaalenii_PYR-1       LFDLAVIGRLGALNLAGLAIGALIMGVLSSQLTFLSYG------TTARAA
MSMEG_2631|M.smegmatis_MC2_155      LFDLAIVGRLGAVSLAGLAIGGLVLGLVNSQGTFLSYG------TTARSA
MAB_3128c|M.abscessus_ATCC_199      LFDIAMVGRLGAVPLAGLAVGGLVLSLVGTQLTFLSYG------TTARAA
MAV_5113|M.avium_104                SIGYARREHLGRVSLAMLPLFVAAMMLVPAAGSVTTFLLAWELMATASLV
                                     :. *   :** : ** *.:    : :: :  :. ::       :**  .

Rv2836c|M.tuberculosis_H37Rv        RRYGAGNRVAAVTEG------VQATWLALGLGALVVVVVEAT--------
Mb2861c|M.bovis_AF2122/97           RRYGAGNRVAAVTEG------VQATWLALGLGALVVVVVEAT--------
MMAR_1897|M.marinum_M               RHYGAGDRVAAVAEG------VQATWLAVALGLLTILVVQIA--------
MUL_2125|M.ulcerans_Agy99           RHYGAGDRVAAVAEG------VQATWLAVALGLLTILVVQIA--------
Mflv_4036|M.gilvum_PYR-GCK          RFYGAGDRNAAVEEG------VQATWLAVGIGTVIVAAVQVT--------
Mvan_2317|M.vanbaalenii_PYR-1       RFYGAGNRTAAVEEG------VQATWLALGIGTTIVVAVQLT--------
MSMEG_2631|M.smegmatis_MC2_155      RFYGAGDRTSAVAEG------VQATWLALGLGLLIIAVVEAV--------
MAB_3128c|M.abscessus_ATCC_199      RRFGSGDRPGAVHEG------VQATWLALLIGAVVVLVVHAV--------
MAV_5113|M.avium_104                LVLAQHTRPEVRSAGLFYAVMTQLGFVAILIGLMVLSAAGGADRFADLTR
                                       .   *  .   *      .*  ::*: :*   : ..  .        

Rv2836c|M.tuberculosis_H37Rv        ----ATPLVSAIA---SGDG-ITAAALPWLRIAILGTPAILVSLAGNGWL
Mb2861c|M.bovis_AF2122/97           ----ATPLVSAIA---SGDG-ITAAALPWLRIAILGTPAILVSLAGNGWL
MMAR_1897|M.marinum_M               ----AVPLVSVIAGARAGSGDIAGAALPWLRIAILGTPAILISLAGNGWM
MUL_2125|M.ulcerans_Agy99           ----AVPLVSVIAGARAGSGDIAGAALPWLWIAILGTPAILISLAGNGWM
Mflv_4036|M.gilvum_PYR-GCK          ----AVPLVSALAAG----GEIAETALPWVRIASLAVPAILIAAAGNGWM
Mvan_2317|M.vanbaalenii_PYR-1       ----AVPLVSVLAGGAD-HGRIAETALPWVRIASLAVPAILIAAAGNGWM
MSMEG_2631|M.smegmatis_MC2_155      ----AVPMLSALAAG----GEIAHAALPWLRVAILAAPAILVSMAGNGWM
MAB_3128c|M.abscessus_ATCC_199      ----AGPVVRAIAAA----PDVAAQGLGWLRIAIFAAPAILVSLAGNGWM
MAV_5113|M.avium_104                VSDGARTVVFVLTMAGFGSKAGLVPLHAWLPRAHPEAPSPVSALMSAAMV
                                        * .:: .::               *:  *   .*: : :  . . :

Rv2836c|M.tuberculosis_H37Rv        RGVQDTVRPLRYVVAGFGSSALLCPLLVYG-----------WLGLPRWGL
Mb2861c|M.bovis_AF2122/97           RGVQDTVRPLRYVVAGFGSSALLCPLLVYG-----------WLGLPRWGL
MMAR_1897|M.marinum_M               RGVQDTVRPLRYVVAGFGLSALLCPLLVYG-----------WLGLPRMEL
MUL_2125|M.ulcerans_Agy99           RGVQDTVRPLRYVVAGFGLSALLCPLLVYG-----------WLGLPRMEL
Mflv_4036|M.gilvum_PYR-GCK          RGVQDTMRPLRYVVVGFGLSAVLCPLLVFG-----------WLGCPELGL
Mvan_2317|M.vanbaalenii_PYR-1       RGVQDTMRPLRYVIFGFAVSAVLCPLLVYG-----------WLGAPELGL
MSMEG_2631|M.smegmatis_MC2_155      RGVQDTVRPLRYVVLGFAVSAVLCPLLVYG-----------WLGFPRLEL
MAB_3128c|M.abscessus_ATCC_199      RGVQNTVRPLRYVIAGFAVSAVLCPVLIYG-----------LAGVPRMGL
MAV_5113|M.avium_104                NLGVYGIVRFDLQLLGPGPRWWAITLLVVGGVSAVYGVLQASVATDLKRL
                                    .     :  :   : * .      .:*: *             .     *

Rv2836c|M.tuberculosis_H37Rv        TGSAVANLVGQWLAALLFAGALLAERVSLRPDRAVLGAQLMMARDLIVRT
Mb2861c|M.bovis_AF2122/97           TGSAVANLVGQWLAALLFAGALLAERVSLRPDRAVLGAQLMMARDLIVRT
MMAR_1897|M.marinum_M               AGSAVANLVGQWLAALLFGGALLAERVSLRPDRHILREQLVLARDLIVRT
MUL_2125|M.ulcerans_Agy99           AGSAVANLVGQWLAALLFGGALLAERVSLRPDRHILREQLVLARDLIVRT
Mflv_4036|M.gilvum_PYR-GCK          PGSAVANVAGQYLAAALFCRALFVEKVPLRVRPAVLRAQVVMGRDLILRT
Mvan_2317|M.vanbaalenii_PYR-1       PGSAVANVVGQYLAAALFCRALVVEKVPLRLRPPVLRAQVVMGRDLVLRT
MSMEG_2631|M.smegmatis_MC2_155      AGSAVANVVGQWLAAGLFMRALLVEKVPLRLRPDVLRVQLVMGRDLLLRS
MAB_3128c|M.abscessus_ATCC_199      AGSAVANLVGQWLAAILFLRALHAEHAPLRTDRAVLRAQLVLARDLLVRS
MAV_5113|M.avium_104                LAYSTTENMGLITLALGAATLLADSGAHSAATIAMAAALLHLIGHAAFKS
                                     . :.::  *    *      *  . .       :    : :  .  .::

Rv2836c|M.tuberculosis_H37Rv        LAFQVCYVSAAAVAAR---FGAAALAAHQVVLQLWGLLALVLDSLAIAAQ
Mb2861c|M.bovis_AF2122/97           LAFQVCYVSAAAVAAR---FGAAALAAHQVVLQLWGLLALVLDSLAIAAQ
MMAR_1897|M.marinum_M               MAFQACFISAAAVAAR---FGAAALAAHQVVLQLWGFFALVLDSLAIAAQ
MUL_2125|M.ulcerans_Agy99           MAFQACFISAAAVAAR---FGAAALAAHQVVLQLWGFFALVLDSLAIAAQ
Mflv_4036|M.gilvum_PYR-GCK          MAFQACFISAGAVAAR---FGAASVAAHQVVLQLWSFLALVLDSLAIAAQ
Mvan_2317|M.vanbaalenii_PYR-1       MAFQACFISAGAVAAR---FGAAAVAAHQVVLQLWNFLALVLDSLAIAAQ
MSMEG_2631|M.smegmatis_MC2_155      LAFQACFVSAGAVAAR---FGAAAVAAHQVVLQLWSFLALVLDSLAIAAQ
MAB_3128c|M.abscessus_ATCC_199      LAFQACFISAAAVAAR---FGAAALAAHQVVLQMWSFLALVLDSLAIAAQ
MAV_5113|M.avium_104                LGFLAAGSVLAATGLRDLDLLGGLARRMPATTALFGVAALGASGLPLGAG
                                    :.* ..    .*.. *   : ..      ..  ::.. **  ..*.:.* 

Rv2836c|M.tuberculosis_H37Rv        SLVGAALGAGDAGHAKAVAWRVTAFSLLAAGILAAALGLGSSVLPGLFTD
Mb2861c|M.bovis_AF2122/97           SLVGAALGAGDAGHAKAVAWRVTAFSLLAAGILAAALGLGSSVLPGLFTD
MMAR_1897|M.marinum_M               SLVGAALGAGDAAHAKWVAWRVTVFSLLAAGMLAAALALGAPVLPALFTD
MUL_2125|M.ulcerans_Agy99           SLVGAALGAGDAAHAKWVAWRVTVFSLLAAGMLAAALALGAPVLPALFTD
Mflv_4036|M.gilvum_PYR-GCK          SLVGAALGAGQLTHAKAVAWRVTIFSAVAGVVLAVVFALGSQLIPSAFTD
Mvan_2317|M.vanbaalenii_PYR-1       SLVGAALGAGQLTHAKAVAWRVTIFSTVAGVVLATVFALGSSVFPAVFTD
MSMEG_2631|M.smegmatis_MC2_155      SLVGAALGAGQLAHAKSVAWRVTLFSTLAGVVLAVVFAVGASVFPPVFTD
MAB_3128c|M.abscessus_ATCC_199      TLVGAALGAGRVPEAKSVAWRVSIFSLGFAVLLAGILALGAPVLPRLFTS
MAV_5113|M.avium_104                FVSEWLLVQSLIHAAPQHNTVVALAAPLAVGAVALTTGLGVAAMVKAFGI
                                     :    *  .    *      *:  :      :*   .:*   :   *  

Rv2836c|M.tuberculosis_H37Rv        -------DRSVLAAIGVPWWFMVVQLPFAG--IVFAVDGVLLG--AGDAA
Mb2861c|M.bovis_AF2122/97           -------DRSVLAAIGVLWWFMVVQLPFAG--IVFAVDGVLLG--AGDAA
MMAR_1897|M.marinum_M               -------DAAVLAAVTVPWWFLVAQLPFAG--IVFALDGVLLG--AGDAA
MUL_2125|M.ulcerans_Agy99           -------DAAVLAAITVPWWFLVAQLPFAG--VVFALDGVLLG--AGDAA
Mflv_4036|M.gilvum_PYR-GCK          -------DQSVLDRIGVPWWFLVAQLPVAG--IVFAIDGVLLG--AGDAT
Mvan_2317|M.vanbaalenii_PYR-1       -------DRSVLDQIGVPWWFLVAQLPVAG--IVFAIDGVLLG--AGDAT
MSMEG_2631|M.smegmatis_MC2_155      -------DESVLATIGVPWWFLVAQLPVAG--IVFALDGVLLG--AGDAK
MAB_3128c|M.abscessus_ATCC_199      -------DAAVLHEMRVPWWFLVCQLPISG--LVFALDGVLLG--AADAR
MAV_5113|M.avium_104                GFLARPRSQPAADAREVPAVMVAGMALAATGCVVVAVAPLVVGSMLGRVL
                                           . ..     *   ::.     :   :*.*:  :::*   . . 

Rv2836c|M.tuberculosis_H37Rv        FMRTATVASALVGFLPLVWLSLAYG-WGLAGIWSGLGTFIVLRLIFVGWR
Mb2861c|M.bovis_AF2122/97           FMRTATVASALVGFLPLVWLSLAYG-WGLAGIWSGLGTFIVLRLIFVGWR
MMAR_1897|M.marinum_M               FMRTATVVSALAGFLPLTWLSLVYG-WGLAGIWSGLATFIVLRLIFVGWR
MUL_2125|M.ulcerans_Agy99           FMRTATVVSALAGFLPLTWLSLVYG-WGLAGIWSGLATFIVLRLIFVGWR
Mflv_4036|M.gilvum_PYR-GCK          FMRNATLASALAGFLPLVWLSLAFG-WGLLGIWAGLSTFMVLRLVFVGWR
Mvan_2317|M.vanbaalenii_PYR-1       FMRNATLISALVGFLPLIWLSLAFG-WGLLGIWAGLSAFMVLRLVFVGWR
MSMEG_2631|M.smegmatis_MC2_155      FMRNATLASAMLGFLPLIWLSLAFG-WGLFGIWSGLSTFMVLRLVFVGWR
MAB_3128c|M.abscessus_ATCC_199      FMRNATMISALCGFLPSVWLALVFG-WGLAGIWCGLTLFLVLRLVLVGWR
MAV_5113|M.avium_104                TELPASRAVAFTDFGAVLRLPGLHGSIAPGAIAAALAAAVLAAVGLACWR
                                        *:   *: .* .   *.  .*  .  .* ..*   ::  : :. **

Rv2836c|M.tuberculosis_H37Rv        AYSGR-------WAVTGAA-------------------------------
Mb2861c|M.bovis_AF2122/97           AYSGR-------WAVTGAA-------------------------------
MMAR_1897|M.marinum_M               AMSGR-------WALTGTA-------------------------------
MUL_2125|M.ulcerans_Agy99           AMSGR-------WALTGTA-------------------------------
Mflv_4036|M.gilvum_PYR-GCK          ALSGR-------WLVPGTR-------------------------------
Mvan_2317|M.vanbaalenii_PYR-1       ALSGR-------WLVPGTR-------------------------------
MSMEG_2631|M.smegmatis_MC2_155      AFSGR-------WLVPGTS-------------------------------
MAB_3128c|M.abscessus_ATCC_199      ALSGG-------WAVPGTGS------------------------------
MAV_5113|M.avium_104                SRRRSDPVTLPLWACGADELTPRMQYTATSFAEPLQRVFDDVLRPDTDIE
                                    :           *   .                                 

Rv2836c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2861c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1897|M.marinum_M               --------------------------------------------------
MUL_2125|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4036|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2317|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2631|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3128c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_5113|M.avium_104                ITHLTESRYLAEAVTYRTRIADAIEERLYAPVIGAVAAAAQLVRRAHTGS
                                                                                      

Rv2836c|M.tuberculosis_H37Rv        --------------------
Mb2861c|M.bovis_AF2122/97           --------------------
MMAR_1897|M.marinum_M               --------------------
MUL_2125|M.ulcerans_Agy99           --------------------
Mflv_4036|M.gilvum_PYR-GCK          --------------------
Mvan_2317|M.vanbaalenii_PYR-1       --------------------
MSMEG_2631|M.smegmatis_MC2_155      --------------------
MAB_3128c|M.abscessus_ATCC_199      --------------------
MAV_5113|M.avium_104                VHLYLAYGMLGVLIVLVVAR