For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MGPDAGRPDAGGRKIAALALPALGVLAAEPLYLLFDTAVIGRLGALALAGLAIGSLVLGLVGSQATFLSY GTTARSARHYGAGDRVAAVAEGVQATWLAVALGLLTILVVQIAAVPLVSVIAGARAGSGDIAGAALPWLW IAILGTPAILISLAGNGWMRGVQDTVRPLRYVVAGFGLSALLCPLLVYGWLGLPRMELAGSAVANLVGQW LAALLFGGALLAERVSLRPDRHILREQLVLARDLIVRTMAFQACFISAAAVAARFGAAALAAHQVVLQLW GFFALVLDSLAIAAQSLVGAALGAGDAAHAKWVAWRVTVFSLLAAGMLAAALALGAPVLPALFTDDAAVL AAITVPWWFLVAQLPFAGVVFALDGVLLGAGDAAFMRTATVVSALAGFLPLTWLSLVYGWGLAGIWSGLA TFIVLRLIFVGWRAMSGRWALTGTA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2125 | dinF | - | 100% (445) | DNA-damage-inducible protein F DinF |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2861c | dinF | 0.0 | 83.30% (437) | DNA-damage-inducible protein F |
| M. gilvum PYR-GCK | Mflv_4036 | - | 1e-177 | 71.26% (435) | MATE efflux family protein |
| M. tuberculosis H37Rv | Rv2836c | dinF | 0.0 | 83.52% (437) | DNA-damage-inducible protein F |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3128c | - | 1e-174 | 71.14% (440) | DNA-damage-inducible protein F |
| M. marinum M | MMAR_1897 | dinF | 0.0 | 99.33% (445) | DNA-damage-inducible protein F DinF |
| M. avium 104 | MAV_1387 | - | 3e-05 | 29.88% (164) | drug transporter |
| M. smegmatis MC2 155 | MSMEG_2631 | - | 0.0 | 73.27% (449) | MATE efflux family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2317 | - | 1e-177 | 71.72% (435) | MATE efflux family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2125|M.ulcerans_Agy99 --------MGPDAGRP--------------------------------DA
MMAR_1897|M.marinum_M --------MGPDAGRP--------------------------------DA
Mb2861c|M.bovis_AF2122/97 --------MSQVGHR----------------------------------A
Rv2836c|M.tuberculosis_H37Rv --------MSQVGHR----------------------------------A
Mflv_4036|M.gilvum_PYR-GCK --------MADP----------------------------------VAPA
Mvan_2317|M.vanbaalenii_PYR-1 --------MAEP----------------------------------VAPA
MSMEG_2631|M.smegmatis_MC2_155 --------MADAAGDLPGGPDDDAQGAA------------------LTQA
MAB_3128c|M.abscessus_ATCC_199 --------MTDATGIAG------------------------------MPG
MAV_1387|M.avium_104 MMIGFFMIMVDSTIVAIANPTIMADLHIGYDTVVWVTSAYLLGYAVVLLV
*
MUL_2125|M.ulcerans_Agy99 GGRK-----IAALALPALGVLAAEPLYLLFDTAVIGRLGALALAGLAIGS
MMAR_1897|M.marinum_M GGRK-----IAALALPALGVLAAEPLYLLFDTAVIGRLGALALAGLAIGS
Mb2861c|M.bovis_AF2122/97 GGRQ-----IAQLALPALGVLAAEPLYLLFDIAVVGRLGAISLAGLAIGS
Rv2836c|M.tuberculosis_H37Rv GGRQ-----IAQLALPALGVLAAEPLYLLFDIAVVGRLGAISLAGLAIGS
Mflv_4036|M.gilvum_PYR-GCK TGRR-----IAGLAFPALGVLAAEPVYLLFDLAIVGRLGALSLAGLAIGA
Mvan_2317|M.vanbaalenii_PYR-1 SSRR-----IAALAFPALGVLAAEPIYLLFDLAVIGRLGALNLAGLAIGA
MSMEG_2631|M.smegmatis_MC2_155 TGRR-----IAKLAFPALGVLAAEPIYLLFDLAIVGRLGAVSLAGLAIGG
MAB_3128c|M.abscessus_ATCC_199 LARR-----IISLALPALGVLAAEPLYLLFDIAMVGRLGAVPLAGLAVGG
MAV_1387|M.avium_104 AGRLGDRFGTKNLYLIGLAVFTVASVWCGLAGSAAMLIAARVVQGVGAGV
.* * : .*.*::. .:: : : :.* : *:. *
MUL_2125|M.ulcerans_Agy99 LVLGLVGSQATFLSYGTTARSARHYGAGDRVAAVAEGVQATWLAVALGLL
MMAR_1897|M.marinum_M LVLGLVGSQATFLSYGTTARSARHYGAGDRVAAVAEGVQATWLAVALGLL
Mb2861c|M.bovis_AF2122/97 LVLGLVGSQATFLSYGTTARAARRYGAGNRVAAVTEGVQATWLALGLGAL
Rv2836c|M.tuberculosis_H37Rv LVLGLVGSQATFLSYGTTARAARRYGAGNRVAAVTEGVQATWLALGLGAL
Mflv_4036|M.gilvum_PYR-GCK LIMGVLSSQLTFLSYGTTARAARFYGAGDRNAAVEEGVQATWLAVGIGTV
Mvan_2317|M.vanbaalenii_PYR-1 LIMGVLSSQLTFLSYGTTARAARFYGAGNRTAAVEEGVQATWLALGIGTT
MSMEG_2631|M.smegmatis_MC2_155 LVLGLVNSQGTFLSYGTTARSARFYGAGDRTSAVAEGVQATWLALGLGLL
MAB_3128c|M.abscessus_ATCC_199 LVLSLVGTQLTFLSYGTTARAARRFGSGDRPGAVHEGVQATWLALLIGAV
MAV_1387|M.avium_104 MTPQTLSTITRIFPAERRGVAVSVWSATAGAASLAGPLAGGVLVDGLGWQ
: :.: ::. . :. :.: .:: : . *. :*
MUL_2125|M.ulcerans_Agy99 TILVVQIAAVPLVSVIAGARAGSGDIAGAALPWLWIAILGTPAILISLAG
MMAR_1897|M.marinum_M TILVVQIAAVPLVSVIAGARAGSGDIAGAALPWLRIAILGTPAILISLAG
Mb2861c|M.bovis_AF2122/97 VVVVVEATATPLVSAIA---SGDG-ITAAALPWLRIAILGTPAILVSLAG
Rv2836c|M.tuberculosis_H37Rv VVVVVEATATPLVSAIA---SGDG-ITAAALPWLRIAILGTPAILVSLAG
Mflv_4036|M.gilvum_PYR-GCK IVAAVQVTAVPLVSALAAG----GEIAETALPWVRIASLAVPAILIAAAG
Mvan_2317|M.vanbaalenii_PYR-1 IVVAVQLTAVPLVSVLAGGAD-HGRIAETALPWVRIASLAVPAILIAAAG
MSMEG_2631|M.smegmatis_MC2_155 IIAVVEAVAVPMLSALAAG----GEIAHAALPWLRVAILAAPAILVSMAG
MAB_3128c|M.abscessus_ATCC_199 VVLVVHAVAGPVVRAIAAA----PDVAAQGLGWLRIAIFAAPAILVSLAG
MAV_1387|M.avium_104 WIFFVNVPIGVLGLVLAYWLVPVLPTQSHRFDLVGVGLSGVGMLLIVFGL
: *. : .:* : : :. .. :*: .
MUL_2125|M.ulcerans_Agy99 -NGWMRGVQDTVRPLRYVVAGFG----------LSALLCPLLVYG-----
MMAR_1897|M.marinum_M -NGWMRGVQDTVRPLRYVVAGFG----------LSALLCPLLVYG-----
Mb2861c|M.bovis_AF2122/97 -NGWLRGVQDTVRPLRYVVAGFG----------SSALLCPLLVYG-----
Rv2836c|M.tuberculosis_H37Rv -NGWLRGVQDTVRPLRYVVAGFG----------SSALLCPLLVYG-----
Mflv_4036|M.gilvum_PYR-GCK -NGWMRGVQDTMRPLRYVVVGFG----------LSAVLCPLLVFG-----
Mvan_2317|M.vanbaalenii_PYR-1 -NGWMRGVQDTMRPLRYVIFGFA----------VSAVLCPLLVYG-----
MSMEG_2631|M.smegmatis_MC2_155 -NGWMRGVQDTVRPLRYVVLGFA----------VSAVLCPLLVYG-----
MAB_3128c|M.abscessus_ATCC_199 -NGWMRGVQNTVRPLRYVIAGFA----------VSAVLCPVLIYG-----
MAV_1387|M.avium_104 QQGQAAHWQPWIWALIVAGVGFVTVFVFWQSVNVREPLIPLVIFSDRDFS
:* * : .* . ** * *::::.
MUL_2125|M.ulcerans_Agy99 --WLGLPRMELAGSAVAN---------------LVGQWLAALLFGGALLA
MMAR_1897|M.marinum_M --WLGLPRMELAGSAVAN---------------LVGQWLAALLFGGALLA
Mb2861c|M.bovis_AF2122/97 --WLGLPRWGLTGSAVAN---------------LVGQWLAALLFAGALLA
Rv2836c|M.tuberculosis_H37Rv --WLGLPRWGLTGSAVAN---------------LVGQWLAALLFAGALLA
Mflv_4036|M.gilvum_PYR-GCK --WLGCPELGLPGSAVAN---------------VAGQYLAAALFCRALFV
Mvan_2317|M.vanbaalenii_PYR-1 --WLGAPELGLPGSAVAN---------------VVGQYLAAALFCRALVV
MSMEG_2631|M.smegmatis_MC2_155 --WLGFPRLELAGSAVAN---------------VVGQWLAAGLFMRALLV
MAB_3128c|M.abscessus_ATCC_199 --LAGVPRMGLAGSAVAN---------------LVGQWLAAILFLRALHA
MAV_1387|M.avium_104 LCNIGVAIISFAATAMMLPLTFYAQAVCGLSPTRSALLIAPMAIANGVFA
* . :..:*: . :*. : .: .
MUL_2125|M.ulcerans_Agy99 ERVSLRPDRHILREQLVLARDLIVRTMAFQACFISAAAVAARFGAAALAA
MMAR_1897|M.marinum_M ERVSLRPDRHILREQLVLARDLIVRTMAFQACFISAAAVAARFGAAALAA
Mb2861c|M.bovis_AF2122/97 ERVSLRPDRAVLGAQLMMARDLIVRTLAFQVCYVSAAAVAARFGAAALAA
Rv2836c|M.tuberculosis_H37Rv ERVSLRPDRAVLGAQLMMARDLIVRTLAFQVCYVSAAAVAARFGAAALAA
Mflv_4036|M.gilvum_PYR-GCK EKVPLRVRPAVLRAQVVMGRDLILRTMAFQACFISAGAVAARFGAASVAA
Mvan_2317|M.vanbaalenii_PYR-1 EKVPLRLRPPVLRAQVVMGRDLVLRTMAFQACFISAGAVAARFGAAAVAA
MSMEG_2631|M.smegmatis_MC2_155 EKVPLRLRPDVLRVQLVMGRDLLLRSLAFQACFVSAGAVAARFGAAAVAA
MAB_3128c|M.abscessus_ATCC_199 EHAPLRTDRAVLRAQLVLARDLLVRSLAFQACFISAAAVAARFGAAALAA
MAV_1387|M.avium_104 PFVGKIVDRYHPRPVLGFGFSLLAIALTWLTFEMSPATPIWRLVLPFFAM
. : :. .*: :::: . :*..: *: . .*
MUL_2125|M.ulcerans_Agy99 HQVVLQLWGFFALVLDSLAIAAQSLVGAALG--AGDAAHAKWVAWRVTVF
MMAR_1897|M.marinum_M HQVVLQLWGFFALVLDSLAIAAQSLVGAALG--AGDAAHAKWVAWRVTVF
Mb2861c|M.bovis_AF2122/97 HQVVLQLWGLLALVLDSLAIAAQSLVGAALG--AGDAGHAKAVAWRVTAF
Rv2836c|M.tuberculosis_H37Rv HQVVLQLWGLLALVLDSLAIAAQSLVGAALG--AGDAGHAKAVAWRVTAF
Mflv_4036|M.gilvum_PYR-GCK HQVVLQLWSFLALVLDSLAIAAQSLVGAALG--AGQLTHAKAVAWRVTIF
Mvan_2317|M.vanbaalenii_PYR-1 HQVVLQLWNFLALVLDSLAIAAQSLVGAALG--AGQLTHAKAVAWRVTIF
MSMEG_2631|M.smegmatis_MC2_155 HQVVLQLWSFLALVLDSLAIAAQSLVGAALG--AGQLAHAKSVAWRVTLF
MAB_3128c|M.abscessus_ATCC_199 HQVVLQMWSFLALVLDSLAIAAQTLVGAALG--AGRVPEAKSVAWRVSIF
MAV_1387|M.avium_104 GVGMAFVWSPLTATATRNLSAQLAGAGSAVYNSVRQLGAVLGSAGMAAFM
: :*. :: . * : .*:*: . . * .: :
MUL_2125|M.ulcerans_Agy99 SLLAAGMLAAALALG-----APVLPALFTDDAAVLAAITVPWWFLVAQLP
MMAR_1897|M.marinum_M SLLAAGMLAAALALG-----APVLPALFTDDAAVLAAVTVPWWFLVAQLP
Mb2861c|M.bovis_AF2122/97 SLLAAGILAAALGLG-----SSVLPGLFTDDRSVLAAIGVLWWFMVVQLP
Rv2836c|M.tuberculosis_H37Rv SLLAAGILAAALGLG-----SSVLPGLFTDDRSVLAAIGVPWWFMVVQLP
Mflv_4036|M.gilvum_PYR-GCK SAVAGVVLAVVFALG-----SQLIPSAFTDDQSVLDRIGVPWWFLVAQLP
Mvan_2317|M.vanbaalenii_PYR-1 STVAGVVLATVFALG-----SSVFPAVFTDDRSVLDQIGVPWWFLVAQLP
MSMEG_2631|M.smegmatis_MC2_155 STLAGVVLAVVFAVG-----ASVFPPVFTDDESVLATIGVPWWFLVAQLP
MAB_3128c|M.abscessus_ATCC_199 SLGFAVLLAGILALG-----APVLPRLFTSDAAVLHEMRVPWWFLVCQLP
MAV_1387|M.avium_104 TWRIGAEMPGQPGGGGEDSAGPVLPEFLRGPFAAAMSQSVLLPAFIALFG
: . :. . * . ::* : . :. * :: :
MUL_2125|M.ulcerans_Agy99 FAGVVFALDG-----------------------------------VLLG-
MMAR_1897|M.marinum_M FAGIVFALDG-----------------------------------VLLG-
Mb2861c|M.bovis_AF2122/97 FAGIVFAVDG-----------------------------------VLLG-
Rv2836c|M.tuberculosis_H37Rv FAGIVFAVDG-----------------------------------VLLG-
Mflv_4036|M.gilvum_PYR-GCK VAGIVFAIDG-----------------------------------VLLG-
Mvan_2317|M.vanbaalenii_PYR-1 VAGIVFAIDG-----------------------------------VLLG-
MSMEG_2631|M.smegmatis_MC2_155 VAGIVFALDG-----------------------------------VLLG-
MAB_3128c|M.abscessus_ATCC_199 ISGLVFALDG-----------------------------------VLLG-
MAV_1387|M.avium_104 IVAALFLVGFRPWAHRDGGTDAFGPDDYGGDYHDDYDDDDAYVELILVRE
. . :* :. :*:
MUL_2125|M.ulcerans_Agy99 -------------------AGDAAFMRTATVVS--ALAGFLPLTWLSLVY
MMAR_1897|M.marinum_M -------------------AGDAAFMRTATVVS--ALAGFLPLTWLSLVY
Mb2861c|M.bovis_AF2122/97 -------------------AGDAAFMRTATVAS--ALVGFLPLVWLSLAY
Rv2836c|M.tuberculosis_H37Rv -------------------AGDAAFMRTATVAS--ALVGFLPLVWLSLAY
Mflv_4036|M.gilvum_PYR-GCK -------------------AGDATFMRNATLAS--ALAGFLPLVWLSLAF
Mvan_2317|M.vanbaalenii_PYR-1 -------------------AGDATFMRNATLIS--ALVGFLPLIWLSLAF
MSMEG_2631|M.smegmatis_MC2_155 -------------------AGDAKFMRNATLAS--AMLGFLPLIWLSLAF
MAB_3128c|M.abscessus_ATCC_199 -------------------AADARFMRNATMIS--ALCGFLPSVWLALVF
MAV_1387|M.avium_104 PEPEAQQRAGQPRRPQPTPAPPADVRRRDPVESRRSVLDERPAQVQPIGF
* * . * .: * :: . * .: :
MUL_2125|M.ulcerans_Agy99 GWGLAGIWSG--LATFIVLRLIFVG-------------WRAMSGRWALTG
MMAR_1897|M.marinum_M GWGLAGIWSG--LATFIVLRLIFVG-------------WRAMSGRWALTG
Mb2861c|M.bovis_AF2122/97 GWGLAGIWSG--LGTFIVLRLIFVG-------------WRAYSGRWAVTG
Rv2836c|M.tuberculosis_H37Rv GWGLAGIWSG--LGTFIVLRLIFVG-------------WRAYSGRWAVTG
Mflv_4036|M.gilvum_PYR-GCK GWGLLGIWAG--LSTFMVLRLVFVG-------------WRALSGRWLVPG
Mvan_2317|M.vanbaalenii_PYR-1 GWGLLGIWAG--LSAFMVLRLVFVG-------------WRALSGRWLVPG
MSMEG_2631|M.smegmatis_MC2_155 GWGLFGIWSG--LSTFMVLRLVFVG-------------WRAFSGRWLVPG
MAB_3128c|M.abscessus_ATCC_199 GWGLAGIWCG--LTLFLVLRLVLVG-------------WRALSGGWAVPG
MAV_1387|M.avium_104 AHNGSHVDGGKRLRQVAVRRAPKPGPPADRFTRPPRRHHPGPAGHHLGEG
. . : * * . * * * . :* *
MUL_2125|M.ulcerans_Agy99 TA------------------------
MMAR_1897|M.marinum_M TA------------------------
Mb2861c|M.bovis_AF2122/97 AA------------------------
Rv2836c|M.tuberculosis_H37Rv AA------------------------
Mflv_4036|M.gilvum_PYR-GCK TR------------------------
Mvan_2317|M.vanbaalenii_PYR-1 TR------------------------
MSMEG_2631|M.smegmatis_MC2_155 TS------------------------
MAB_3128c|M.abscessus_ATCC_199 TGS-----------------------
MAV_1387|M.avium_104 ESLRGQHHRPDPDDDPTGYGRHSSGN